Vertex Pharmaceuticals, Inc.. (VRTX) NASDAQ
$349.65 (2.04) (-0.58%)
Market Cap: $90.24B
As of 09/27/23 04:00 PM EDT. Market closed.
Vertex Pharmaceuticals, Inc.. (VRTX)
NASDAQ
$349.65
(2.04) (-0.58%)
Market Cap: $90.24B
As of 09/27/23 04:00 PM EDT. Market closed.
Vertex Pharmaceuticals is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial ... read more
Vertex Pharmaceuticals is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. read less
COMPANY PROFILE
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
Reshma Kewalramani
Full Time Employees
4,800
CEO Compensation (Base)
$1.30M
CEO Compensation (Total)
$18.80M
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
Reshma Kewalramani
Full Time Employees
4,800
CEO Compensation (Base)
$1.30M
CEO Compensation (Total)
$18.80M
URL
Address
50 Northern Ave, Massachusetts, Boston, 02210-1862.
PRICE CHART FOR VERTEX PHARMACEUTICALS, INC.
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NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
$344.74
Previous Close
$351.69
Days Range
$347.52 - $352.91
52 week range
$282.21 - $367
Volume
468,952
Avg. Volume (30 days)
911,419
Market Cap
$90.24B
Dividend Yield
-
P/E
26.82
Shares Outstanding
258,094,815
Open
$344.74
Previous Close
$351.69
Days Range
$347.52 - $352.91
52 week range
$282.21 - $367
Volume
468,952
Avg. Volume (30 days)
911,419
Market Cap
$90.24B
Dividend Yield
-
P/E
26.82
Shares Outstanding
258,094,815
FINANCIAL STATEMENTS FOR VERTEX PHARMACEUTICALS, INC.
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INSIDER TRANSACTIONS FOR VERTEX PHARMACEUTICALS, INC.
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| Bozic Carmen | EVP and CMO | Sep 19, 2023 | Sale | $351.00 | 5,651 | 1,983,501 | 51,905 | Sep 21, 2023, 04:15 PM |
| Bozic Carmen | EVP and CMO | Sep 05, 2023 | Sale | $352.66 | 5,651 | 1,992,882 | 57,556 | Sep 07, 2023, 04:29 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Aug 23, 2023 | Sale | $355.00 | 2,500 | 887,500 | 48,637 | Aug 25, 2023, 04:14 PM |
| Kearney Terrence C | Director | Aug 10, 2023 | Option Exercise | $127.54 | 10,000 | 1,275,400 | 16,536 | Aug 14, 2023, 04:09 PM |
| Kearney Terrence C | Director | Aug 10, 2023 | Sale | $350.00 | 10,000 | 3,500,000 | 6,536 | Aug 14, 2023, 04:09 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Aug 10, 2023 | Sale | $345.79 | 5,750 | 1,988,293 | 51,137 | Aug 14, 2023, 04:08 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Aug 10, 2023 | Sale | $350.00 | 10,031 | 3,510,850 | 58,814 | Aug 14, 2023, 04:05 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 09, 2023 | Sale | $345.51 | 63 | 21,767 | 32,038 | Aug 11, 2023, 04:05 PM |
| Bhatia Sangeeta N. | Director | Aug 09, 2023 | Sale | $345.51 | 242 | 83,613 | 4,386 | Aug 11, 2023, 04:05 PM |
| SACHS BRUCE I | Director | Jul 17, 2023 | Option Exercise | $127.54 | 11,250 | 1,434,825 | 51,250 | Jul 18, 2023, 04:17 PM |
| SACHS BRUCE I | Director | Jul 17, 2023 | Sale | $356.75 | 11,250 | 4,013,459 | 49,553 | Jul 18, 2023, 04:17 PM |
| Kewalramani Reshma | CEO & President | Jul 17, 2023 | Sale | $355.00 | 7,828 | 2,778,940 | 118,906 | Jul 18, 2023, 04:13 PM |
| Arbuckle Stuart A | EVP, COO | Jun 15, 2023 | Option Exercise | $187.53 | 8,603 | 1,613,321 | 65,159 | Jun 20, 2023, 04:07 PM |
| Arbuckle Stuart A | EVP, COO | Jun 15, 2023 | Sale | $349.00 | 8,603 | 3,002,447 | 56,556 | Jun 20, 2023, 04:07 PM |
| Arbuckle Stuart A | EVP, COO | May 30, 2023 | Sale | $329.82 | 82 | 27,045 | 56,556 | Jun 01, 2023, 04:16 PM |
| Ambrose Kristen | SVP & Chief Accounting Officer | May 30, 2023 | Sale | $329.82 | 289 | 95,318 | 6,838 | Jun 01, 2023, 04:12 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | May 05, 2023 | Sale | $350.03 | 422 | 147,713 | 34,888 | May 09, 2023, 04:15 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | May 08, 2023 | Sale | $350.00 | 2,850 | 997,500 | 32,038 | May 09, 2023, 04:15 PM |
| LEIDEN JEFFREY M | Executive Chairman | May 08, 2023 | Sale | $349.00 | 1,125 | 392,625 | 35,387 | May 09, 2023, 04:10 PM |
| LEIDEN JEFFREY M | Executive Chairman | May 05, 2023 | Sale | $349.56 | 879 | 307,262 | 36,683 | May 09, 2023, 04:10 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | May 03, 2023 | Sale | $350.74 | 2,781 | 975,418 | 36,038 | May 04, 2023, 04:51 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | May 02, 2023 | Sale | $350.66 | 1,622 | 568,768 | 38,302 | May 04, 2023, 04:51 PM |
| LEIDEN JEFFREY M | Executive Chairman | May 03, 2023 | Sale | $350.11 | 4,508 | 1,578,301 | 39,891 | May 04, 2023, 04:50 PM |
| LEIDEN JEFFREY M | Executive Chairman | May 02, 2023 | Sale | $349.89 | 6,450 | 2,256,761 | 43,704 | May 04, 2023, 04:50 PM |
| Bhatia Sangeeta N. | Director | May 02, 2023 | Sale | $348.28 | 580 | 202,004 | 5,146 | May 03, 2023, 04:44 PM |
| Kewalramani Reshma | CEO & President | Apr 27, 2023 | Sale | $339.08 | 3,317 | 1,124,726 | 128,358 | May 01, 2023, 04:26 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Apr 12, 2023 | Sale | $326.70 | 7,567 | 2,472,164 | 46,406 | Apr 14, 2023, 04:19 PM |
| SACHS BRUCE I | Director | Apr 12, 2023 | Option Exercise | $72.14 | 21,300 | 1,536,582 | 62,510 | Apr 14, 2023, 04:14 PM |
| SACHS BRUCE I | Director | Apr 12, 2023 | Sale | $326.73 | 21,300 | 6,959,422 | 59,593 | Apr 14, 2023, 04:14 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Apr 04, 2023 | Sale | $315.81 | 522 | 164,854 | 47,591 | Apr 06, 2023, 04:23 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Mar 24, 2023 | Sale | $305.38 | 1,768 | 539,912 | 49,611 | Mar 28, 2023, 04:13 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Mar 17, 2023 | Sale | $296.39 | 2,000 | 592,786 | 53,019 | Mar 21, 2023, 04:21 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Mar 16, 2023 | Sale | $300.59 | 2,746 | 825,423 | 49,532 | Mar 20, 2023, 04:26 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Mar 13, 2023 | Sale | $293.83 | 2,666 | 783,346 | 56,021 | Mar 14, 2023, 04:22 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Mar 10, 2023 | Sale | $289.61 | 2,088 | 604,709 | 57,772 | Mar 14, 2023, 04:22 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Feb 24, 2023 | Option Exercise | $289.12 | 3,308 | 956,409 | 58,133 | Feb 28, 2023, 05:14 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 24, 2023 | Option Exercise | $289.12 | 3,308 | 956,409 | 57,159 | Feb 28, 2023, 05:11 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 27, 2023 | Sale | $287.48 | 354 | 101,768 | 56,876 | Feb 28, 2023, 05:11 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 24, 2023 | Option Exercise | $289.12 | 3,970 | 1,147,806 | 52,014 | Feb 28, 2023, 05:09 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 24, 2023 | Option Exercise | $289.12 | 2,468 | 713,548 | 66,518 | Feb 28, 2023, 05:02 PM |
| LEIDEN JEFFREY M | Executive Chairman | Feb 24, 2023 | Option Exercise | $289.12 | 13,730 | 3,969,618 | 48,349 | Feb 28, 2023, 04:57 PM |
| Kewalramani Reshma | CEO & President | Feb 24, 2023 | Option Exercise | $289.12 | 9,386 | 2,713,680 | 129,969 | Feb 28, 2023, 04:53 PM |
| Bozic Carmen | EVP and CMO | Feb 24, 2023 | Option Exercise | $289.12 | 3,308 | 956,409 | 63,207 | Feb 28, 2023, 04:50 PM |
| Arbuckle Stuart A | EVP, COO | Feb 24, 2023 | Option Exercise | $289.12 | 4,714 | 1,362,912 | 61,590 | Feb 28, 2023, 04:47 PM |
| Arbuckle Stuart A | EVP, COO | Feb 27, 2023 | Sale | $287.47 | 5,034 | 1,447,143 | 57,756 | Feb 28, 2023, 04:47 PM |
| Ambrose Kristen | SVP & Chief Accounting Officer | Feb 24, 2023 | Option Exercise | $289.12 | 502 | 145,138 | 8,510 | Feb 28, 2023, 04:44 PM |
| Ambrose Kristen | SVP & Chief Accounting Officer | Feb 27, 2023 | Sale | $287.55 | 1,207 | 347,072 | 7,528 | Feb 28, 2023, 04:44 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 24, 2023 | Option Exercise | $289.12 | 3,970 | 1,147,806 | 36,276 | Feb 28, 2023, 04:40 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 27, 2023 | Sale | $287.51 | 4,238 | 1,218,450 | 32,640 | Feb 28, 2023, 04:40 PM |
| Arbuckle Stuart A | EVP, COO | Feb 22, 2023 | Sale | $294.33 | 2,401 | 706,679 | 68,576 | Feb 24, 2023, 04:06 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Feb 17, 2023 | Option Exercise | $292.85 | 3,750 | 1,098,188 | 61,441 | Feb 22, 2023, 04:50 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 17, 2023 | Option Exercise | $292.85 | 4,498 | 1,317,239 | 60,947 | Feb 22, 2023, 04:48 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 21, 2023 | Sale | $293.75 | 480 | 141,002 | 60,943 | Feb 22, 2023, 04:48 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 17, 2023 | Option Exercise | $292.85 | 3,750 | 1,098,188 | 55,984 | Feb 22, 2023, 04:46 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 17, 2023 | Option Exercise | $292.85 | 3,498 | 1,024,389 | 68,986 | Feb 22, 2023, 04:43 PM |
| Kewalramani Reshma | CEO & President | Feb 17, 2023 | Option Exercise | $292.85 | 9,359 | 2,740,783 | 139,355 | Feb 22, 2023, 04:35 PM |
| Bozic Carmen | EVP and CMO | Feb 17, 2023 | Option Exercise | $292.85 | 3,750 | 1,098,188 | 66,515 | Feb 22, 2023, 04:32 PM |
| Arbuckle Stuart A | EVP, COO | Feb 17, 2023 | Option Exercise | $292.85 | 4,498 | 1,317,239 | 71,107 | Feb 22, 2023, 04:30 PM |
| Arbuckle Stuart A | EVP, COO | Feb 21, 2023 | Sale | $293.75 | 2,402 | 705,596 | 71,086 | Feb 22, 2023, 04:30 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 17, 2023 | Option Exercise | $292.85 | 3,750 | 1,098,188 | 44,248 | Feb 22, 2023, 04:25 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 21, 2023 | Sale | $293.77 | 4,002 | 1,175,676 | 44,212 | Feb 22, 2023, 04:25 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 14, 2023 | Sale | $298.52 | 320 | 95,527 | 65,694 | Feb 16, 2023, 04:18 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 14, 2023 | Sale | $300.39 | 2,181 | 655,161 | 60,013 | Feb 16, 2023, 04:16 PM |
| Arbuckle Stuart A | EVP, COO | Feb 14, 2023 | Sale | $298.68 | 6,398 | 1,910,962 | 81,203 | Feb 16, 2023, 04:14 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 14, 2023 | Sale | $298.70 | 6,398 | 1,911,108 | 53,596 | Feb 16, 2023, 04:11 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Feb 13, 2023 | Option Exercise | $298.26 | 4,992 | 1,488,914 | 65,191 | Feb 14, 2023, 05:15 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Feb 10, 2023 | Option Exercise | $294.33 | 2,707 | 796,751 | 70,183 | Feb 14, 2023, 05:15 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 13, 2023 | Option Exercise | $298.26 | 2,995 | 893,289 | 66,040 | Feb 14, 2023, 05:12 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 10, 2023 | Option Exercise | $294.33 | 1,377 | 405,292 | 69,035 | Feb 14, 2023, 05:12 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 13, 2023 | Sale | $298.99 | 275 | 82,223 | 66,038 | Feb 14, 2023, 05:12 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 13, 2023 | Option Exercise | $298.26 | 4,340 | 1,294,448 | 62,028 | Feb 14, 2023, 05:08 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 10, 2023 | Option Exercise | $294.33 | 902 | 265,486 | 66,368 | Feb 14, 2023, 05:08 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 13, 2023 | Sale | $300.39 | 113 | 33,944 | 61,915 | Feb 14, 2023, 05:08 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 13, 2023 | Option Exercise | $298.26 | 4,657 | 1,388,997 | 72,484 | Feb 14, 2023, 05:06 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 10, 2023 | Option Exercise | $294.33 | 2,611 | 768,496 | 77,141 | Feb 14, 2023, 05:06 PM |
| LEIDEN JEFFREY M | Executive Chairman | Feb 13, 2023 | Option Exercise | $298.26 | 13,344 | 3,979,982 | 62,079 | Feb 14, 2023, 05:01 PM |
| Kewalramani Reshma | CEO & President | Feb 13, 2023 | Option Exercise | $298.26 | 5,990 | 1,786,577 | 148,714 | Feb 14, 2023, 04:58 PM |
| Kewalramani Reshma | CEO & President | Feb 10, 2023 | Option Exercise | $294.33 | 3,372 | 992,481 | 154,704 | Feb 14, 2023, 04:58 PM |
| Bozic Carmen | EVP and CMO | Feb 13, 2023 | Option Exercise | $298.26 | 4,992 | 1,488,914 | 70,265 | Feb 14, 2023, 04:55 PM |
| Bozic Carmen | EVP and CMO | Feb 10, 2023 | Option Exercise | $294.33 | 2,707 | 796,751 | 75,257 | Feb 14, 2023, 04:55 PM |
| Arbuckle Stuart A | EVP, COO | Feb 13, 2023 | Option Exercise | $298.26 | 5,990 | 1,786,577 | 86,890 | Feb 14, 2023, 04:53 PM |
| Arbuckle Stuart A | EVP, COO | Feb 10, 2023 | Option Exercise | $294.33 | 3,372 | 992,481 | 92,880 | Feb 14, 2023, 04:53 PM |
| Arbuckle Stuart A | EVP, COO | Feb 13, 2023 | Sale | $298.92 | 4,887 | 1,460,816 | 86,645 | Feb 14, 2023, 04:53 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 13, 2023 | Option Exercise | $298.26 | 5,990 | 1,786,577 | 59,194 | Feb 14, 2023, 04:49 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 10, 2023 | Option Exercise | $294.33 | 3,461 | 1,018,676 | 65,184 | Feb 14, 2023, 04:49 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 13, 2023 | Sale | $298.90 | 4,798 | 1,434,126 | 58,949 | Feb 14, 2023, 04:49 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 06, 2023 | Option Exercise | $187.53 | 1,304 | 244,539 | 69,949 | Feb 08, 2023, 04:53 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 06, 2023 | Sale | $306.00 | 1,304 | 399,022 | 69,937 | Feb 08, 2023, 04:53 PM |
| LEIDEN JEFFREY M | Executive Chairman | Feb 02, 2023 | Option Exercise | $317.83 | 3,578 | 1,137,196 | 75,423 | Feb 03, 2023, 04:53 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Jan 31, 2023 | Sale | $325.00 | 106 | 34,450 | 37,998 | Feb 02, 2023, 04:18 PM |
| SACHS BRUCE I | Director | Jan 31, 2023 | Option Exercise | $72.14 | 1,200 | 86,568 | 42,410 | Feb 02, 2023, 04:14 PM |
| SACHS BRUCE I | Director | Jan 31, 2023 | Sale | $325.01 | 1,200 | 390,012 | 41,210 | Feb 02, 2023, 04:14 PM |
| CARNEY LLOYD | Director | Jan 30, 2023 | Sale | $320.52 | 2,700 | 865,406 | 5,474 | Jan 31, 2023, 04:45 PM |
| Lee Yuchun | Director | Jan 27, 2023 | Option Exercise | $72.14 | 1,429 | 103,088 | 3,304 | Jan 31, 2023, 04:42 PM |
| Lee Yuchun | Director | Jan 27, 2023 | Sale | $322.03 | 1,429 | 460,177 | 2,925 | Jan 31, 2023, 04:42 PM |
| Lee Yuchun | Director | Jan 26, 2023 | Option Exercise | $72.14 | 4,000 | 288,560 | 5,875 | Jan 27, 2023, 04:18 PM |
| Lee Yuchun | Director | Jan 25, 2023 | Option Exercise | $72.14 | 4,000 | 288,560 | 5,875 | Jan 27, 2023, 04:18 PM |
| Lee Yuchun | Director | Jan 26, 2023 | Sale | $318.33 | 4,000 | 1,273,322 | 5,573 | Jan 27, 2023, 04:18 PM |
| Lee Yuchun | Director | Jan 25, 2023 | Sale | $313.96 | 4,000 | 1,255,852 | 5,075 | Jan 27, 2023, 04:18 PM |
| Kewalramani Reshma | CEO & President | Jan 25, 2023 | Sale | $315.05 | 10,000 | 3,150,500 | 89,598 | Jan 27, 2023, 04:13 PM |
| Lee Yuchun | Director | Jan 23, 2023 | Option Exercise | $72.14 | 2,129 | 153,586 | 4,004 | Jan 25, 2023, 04:08 PM |
| Lee Yuchun | Director | Jan 24, 2023 | Option Exercise | $72.14 | 4,000 | 288,560 | 5,875 | Jan 25, 2023, 04:08 PM |
| Lee Yuchun | Director | Jan 24, 2023 | Sale | $312.69 | 4,000 | 1,250,753 | 3,364 | Jan 25, 2023, 04:08 PM |
| Lee Yuchun | Director | Jan 23, 2023 | Sale | $312.02 | 2,129 | 664,291 | 1,875 | Jan 25, 2023, 04:08 PM |
| Lee Yuchun | Director | Jan 18, 2023 | Option Exercise | $72.14 | 442 | 31,886 | 2,317 | Jan 19, 2023, 04:07 PM |
| Lee Yuchun | Director | Jan 17, 2023 | Option Exercise | $72.14 | 4,000 | 288,560 | 5,875 | Jan 19, 2023, 04:07 PM |
| Lee Yuchun | Director | Jan 18, 2023 | Sale | $312.17 | 442 | 137,979 | 1,875 | Jan 19, 2023, 04:07 PM |
| Lee Yuchun | Director | Jan 17, 2023 | Sale | $312.03 | 4,000 | 1,248,120 | 1,875 | Jan 19, 2023, 04:07 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 15, 2022 | Sale | $308.61 | 34 | 10,493 | 36,077 | Nov 17, 2022, 04:08 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 07, 2022 | Option Exercise | $187.53 | 1,303 | 244,352 | 37,380 | Nov 09, 2022, 04:40 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 07, 2022 | Sale | $303.04 | 1,303 | 394,859 | 37,240 | Nov 09, 2022, 04:40 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Nov 01, 2022 | Option Exercise | $312.84 | 768 | 240,261 | 38,424 | Nov 03, 2022, 04:05 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Nov 02, 2022 | Sale | $312.64 | 320 | 100,045 | 38,368 | Nov 03, 2022, 04:05 PM |
| Bhatia Sangeeta N. | Director | Oct 24, 2022 | Sale | $310.00 | 621 | 192,510 | 4,040 | Oct 26, 2022, 04:05 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Oct 18, 2022 | Sale | $300.31 | 1,791 | 537,860 | 39,480 | Oct 20, 2022, 04:11 PM |
| Kewalramani Reshma | CEO & President | Aug 15, 2022 | Sale | $305.06 | 11,689 | 3,565,846 | 99,598 | Aug 17, 2022, 05:40 PM |
| Arbuckle Stuart A | EVP, COO | Aug 15, 2022 | Option Exercise | $155.57 | 6,571 | 1,022,251 | 67,451 | Aug 17, 2022, 05:39 PM |
| Arbuckle Stuart A | EVP, COO | Aug 15, 2022 | Sale | $303.93 | 22,173 | 6,738,991 | 66,197 | Aug 17, 2022, 05:39 PM |
| Liu Joy | SVP, General Counsel | Aug 15, 2022 | Sale | $303.90 | 3,747 | 1,138,723 | 13,146 | Aug 17, 2022, 05:36 PM |
| Arbuckle Stuart A | EVP, COO | Aug 10, 2022 | Option Exercise | $155.57 | 64 | 9,956 | 61,060 | Aug 12, 2022, 04:05 PM |
| Arbuckle Stuart A | EVP, COO | Aug 10, 2022 | Sale | $300.40 | 180 | 54,073 | 60,889 | Aug 12, 2022, 04:05 PM |
| Liu Joy | SVP, General Counsel | Aug 10, 2022 | Sale | $300.32 | 36 | 10,812 | 13,352 | Aug 12, 2022, 04:05 PM |
| Bhatia Sangeeta N. | Director | Aug 08, 2022 | Sale | $293.03 | 621 | 181,972 | 5,237 | Aug 10, 2022, 04:07 PM |
| Liu Joy | SVP, General Counsel | Aug 09, 2022 | Sale | $300.00 | 946 | 283,800 | 13,388 | Aug 10, 2022, 04:06 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Aug 09, 2022 | Sale | $298.97 | 1,400 | 418,557 | 47,198 | Aug 10, 2022, 04:06 PM |
| Arbuckle Stuart A | EVP, COO | Aug 09, 2022 | Option Exercise | $155.57 | 1,926 | 299,628 | 66,686 | Aug 10, 2022, 04:06 PM |
| Arbuckle Stuart A | EVP, COO | Aug 09, 2022 | Sale | $300.67 | 5,690 | 1,710,817 | 61,896 | Aug 10, 2022, 04:06 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 08, 2022 | Option Exercise | $187.53 | 1,304 | 244,539 | 37,381 | Aug 10, 2022, 04:06 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 08, 2022 | Sale | $292.54 | 1,304 | 381,469 | 37,159 | Aug 10, 2022, 04:06 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Aug 01, 2022 | Option Exercise | $276.62 | 766 | 211,891 | 40,983 | Aug 03, 2022, 04:05 PM |
| Bhatia Sangeeta N. | Director | Jul 29, 2022 | Sale | $278.77 | 621 | 173,116 | 5,804 | Aug 02, 2022, 04:16 PM |
| LEIDEN JEFFREY M | Executive Chairman | Jul 25, 2022 | Option Exercise | $91.05 | 60,342 | 5,494,139 | 134,502 | Jul 27, 2022, 04:17 PM |
| LEIDEN JEFFREY M | Executive Chairman | Jul 25, 2022 | Sale | $281.38 | 132,079 | 37,164,480 | 120,633 | Jul 27, 2022, 04:17 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jul 19, 2022 | Option Exercise | $174.33 | 17,765 | 3,096,948 | 53,942 | Jul 21, 2022, 04:48 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jul 19, 2022 | Sale | $288.65 | 17,865 | 5,156,730 | 52,979 | Jul 21, 2022, 04:48 PM |
| Kewalramani Reshma | CEO & President | Jun 24, 2022 | Sale | $291.30 | 11,689 | 3,405,006 | 111,153 | Jun 28, 2022, 04:05 PM |
| Bozic Carmen | EVP and CMO | May 31, 2022 | Option Exercise | $271.24 | 311 | 84,356 | 49,512 | Jun 02, 2022, 04:06 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | May 16, 2022 | Sale | $252.83 | 45 | 11,377 | 41,787 | May 18, 2022, 04:22 PM |
| Arbuckle Stuart A | EVP, COO | May 16, 2022 | Sale | $251.19 | 133 | 33,408 | 64,882 | May 18, 2022, 04:21 PM |
| Liu Joy | SVP, General Counsel | May 16, 2022 | Sale | $252.88 | 133 | 33,633 | 14,442 | May 18, 2022, 04:18 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | May 04, 2022 | Sale | $275.09 | 36 | 9,903 | 41,660 | May 06, 2022, 04:05 PM |
| Arbuckle Stuart A | EVP, COO | May 02, 2022 | Sale | $263.98 | 306 | 80,778 | 64,760 | May 04, 2022, 05:21 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | May 02, 2022 | Sale | $259.16 | 320 | 82,930 | 41,996 | May 04, 2022, 05:10 PM |
| Bhatia Sangeeta N. | Director | May 02, 2022 | Sale | $258.94 | 737 | 190,842 | 6,600 | May 04, 2022, 05:09 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | May 02, 2022 | Sale | $258.83 | 343 | 88,778 | 43,053 | May 04, 2022, 05:07 PM |
| Liu Joy | SVP, General Counsel | Apr 29, 2022 | Sale | $275.41 | 120 | 33,049 | 14,437 | May 03, 2022, 04:28 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Apr 29, 2022 | Option Exercise | $276.17 | 547 | 151,065 | 43,073 | May 03, 2022, 04:27 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Apr 29, 2022 | Option Exercise | $276.17 | 766 | 211,546 | 42,016 | May 03, 2022, 04:26 PM |
| Ambrose Kristen | SVP & Chief Accounting Officer | Apr 25, 2022 | Sale | $269.55 | 327 | 88,143 | 3,763 | Apr 27, 2022, 04:05 PM |
| Lee Yuchun | Director | Apr 18, 2022 | Option Exercise | $81.54 | 2,000 | 163,080 | 3,875 | Apr 20, 2022, 04:05 PM |
| Lee Yuchun | Director | Apr 18, 2022 | Sale | $284.23 | 2,000 | 568,467 | 3,493 | Apr 20, 2022, 04:05 PM |
| Lee Yuchun | Director | Apr 14, 2022 | Option Exercise | $81.54 | 2,000 | 163,080 | 3,875 | Apr 18, 2022, 04:05 PM |
| Lee Yuchun | Director | Apr 14, 2022 | Sale | $289.06 | 2,000 | 578,117 | 2,927 | Apr 18, 2022, 04:05 PM |
| LEIDEN JEFFREY M | Executive Chairman | Apr 13, 2022 | Sale | $289.04 | 15,789 | 4,563,653 | 74,160 | Apr 14, 2022, 04:35 PM |
| Lee Yuchun | Director | Apr 13, 2022 | Option Exercise | $81.54 | 2,000 | 163,080 | 3,875 | Apr 14, 2022, 04:35 PM |
| Lee Yuchun | Director | Apr 12, 2022 | Option Exercise | $81.54 | 2,000 | 163,080 | 3,875 | Apr 14, 2022, 04:35 PM |
| Lee Yuchun | Director | Apr 13, 2022 | Sale | $287.50 | 2,000 | 575,009 | 3,857 | Apr 14, 2022, 04:35 PM |
| Lee Yuchun | Director | Apr 12, 2022 | Sale | $281.03 | 2,000 | 562,051 | 3,675 | Apr 14, 2022, 04:35 PM |
| Lee Yuchun | Director | Apr 08, 2022 | Option Exercise | $81.54 | 2,000 | 163,080 | 3,875 | Apr 12, 2022, 04:07 PM |
| Lee Yuchun | Director | Apr 11, 2022 | Option Exercise | $81.54 | 2,000 | 163,080 | 3,875 | Apr 12, 2022, 04:07 PM |
| Lee Yuchun | Director | Apr 08, 2022 | Sale | $278.57 | 2,000 | 557,141 | 3,457 | Apr 12, 2022, 04:07 PM |
| Lee Yuchun | Director | Apr 11, 2022 | Sale | $280.30 | 2,000 | 560,599 | 2,953 | Apr 12, 2022, 04:07 PM |
| Bhatia Sangeeta N. | Director | Apr 08, 2022 | Option Exercise | $125.71 | 1,907 | 239,729 | 7,098 | Apr 12, 2022, 04:05 PM |
| Bhatia Sangeeta N. | Director | Apr 08, 2022 | Sale | $280.20 | 1,907 | 534,341 | 5,191 | Apr 12, 2022, 04:05 PM |
| MCGLYNN MARGARET G | Director | Apr 08, 2022 | Option Exercise | $127.54 | 5,000 | 637,700 | 6,099 | Apr 12, 2022, 04:05 PM |
| MCGLYNN MARGARET G | Director | Apr 08, 2022 | Sale | $280.22 | 5,000 | 1,401,080 | 1,199 | Apr 12, 2022, 04:05 PM |
| Lee Yuchun | Director | Apr 07, 2022 | Option Exercise | $81.54 | 2,000 | 163,080 | 3,875 | Apr 08, 2022, 05:57 PM |
| Lee Yuchun | Director | Apr 06, 2022 | Option Exercise | $81.54 | 2,000 | 163,080 | 3,875 | Apr 08, 2022, 05:57 PM |
| Lee Yuchun | Director | Apr 07, 2022 | Sale | $274.86 | 2,000 | 549,720 | 3,458 | Apr 08, 2022, 05:57 PM |
| Lee Yuchun | Director | Apr 06, 2022 | Sale | $271.62 | 2,000 | 543,243 | 3,858 | Apr 08, 2022, 05:57 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Apr 07, 2022 | Sale | $276.18 | 561 | 154,935 | 43,139 | Apr 08, 2022, 04:34 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Apr 04, 2022 | Sale | $267.71 | 562 | 150,452 | 46,763 | Apr 06, 2022, 05:02 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Apr 05, 2022 | Sale | $275.23 | 3,163 | 870,553 | 43,343 | Apr 06, 2022, 05:02 PM |
| Lee Yuchun | Director | Apr 05, 2022 | Option Exercise | $81.54 | 2,000 | 163,080 | 3,875 | Apr 06, 2022, 04:59 PM |
| Lee Yuchun | Director | Apr 04, 2022 | Option Exercise | $81.54 | 2,000 | 163,080 | 3,875 | Apr 06, 2022, 04:59 PM |
| Lee Yuchun | Director | Apr 05, 2022 | Sale | $272.50 | 2,000 | 544,993 | 3,858 | Apr 06, 2022, 04:59 PM |
| Lee Yuchun | Director | Apr 04, 2022 | Sale | $267.72 | 2,000 | 535,431 | 3,775 | Apr 06, 2022, 04:59 PM |
| Ambrose Kristen | SVP & Chief Accounting Officer | Apr 01, 2022 | Option Exercise | $263.09 | 137 | 36,043 | 3,823 | Apr 05, 2022, 04:06 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Apr 01, 2022 | Sale | $264.76 | 2,582 | 683,602 | 45,902 | Apr 05, 2022, 04:06 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Apr 01, 2022 | Option Exercise | $263.09 | 1,344 | 353,593 | 47,068 | Apr 05, 2022, 04:05 PM |
| MCGLYNN MARGARET G | Director | Mar 31, 2022 | Option Exercise | $127.54 | 5,000 | 637,700 | 6,099 | Apr 04, 2022, 04:05 PM |
| MCGLYNN MARGARET G | Director | Mar 31, 2022 | Sale | $262.27 | 5,000 | 1,311,346 | 5,080 | Apr 04, 2022, 04:05 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Mar 17, 2022 | Sale | $250.11 | 2,833 | 708,572 | 47,390 | Mar 21, 2022, 04:15 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Mar 17, 2022 | Sale | $250.15 | 3,171 | 793,218 | 46,263 | Mar 21, 2022, 04:12 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Mar 17, 2022 | Sale | $250.06 | 2,122 | 530,627 | 48,412 | Mar 21, 2022, 04:10 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Feb 24, 2022 | Option Exercise | $227.86 | 2,189 | 498,786 | 49,373 | Feb 28, 2022, 05:29 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 24, 2022 | Option Exercise | $227.86 | 2,590 | 590,157 | 50,514 | Feb 28, 2022, 05:27 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 25, 2022 | Sale | $230.95 | 325 | 75,058 | 50,486 | Feb 28, 2022, 05:27 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 24, 2022 | Option Exercise | $227.86 | 7,368 | 1,678,872 | 48,210 | Feb 28, 2022, 05:25 PM |
| Liu Joy | SVP, General Counsel | Feb 24, 2022 | Option Exercise | $227.86 | 1,554 | 354,094 | 14,454 | Feb 28, 2022, 05:24 PM |
| LEIDEN JEFFREY M | Executive Chairman | Feb 24, 2022 | Option Exercise | $227.86 | 12,141 | 2,766,448 | 89,949 | Feb 28, 2022, 05:23 PM |
| Kewalramani Reshma | CEO & President | Feb 24, 2022 | Option Exercise | $227.86 | 7,246 | 1,651,074 | 122,842 | Feb 28, 2022, 05:21 PM |
| Bozic Carmen | EVP and CMO | Feb 24, 2022 | Option Exercise | $227.86 | 1,242 | 283,002 | 49,823 | Feb 28, 2022, 05:20 PM |
| Arbuckle Stuart A | EVP, COO | Feb 24, 2022 | Option Exercise | $227.86 | 7,246 | 1,651,074 | 65,066 | Feb 28, 2022, 05:19 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 24, 2022 | Option Exercise | $227.86 | 6,038 | 1,375,819 | 43,649 | Feb 28, 2022, 05:18 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 25, 2022 | Sale | $230.98 | 7,572 | 1,748,990 | 42,609 | Feb 28, 2022, 05:18 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Feb 17, 2022 | Option Exercise | $232.51 | 3,439 | 799,602 | 51,562 | Feb 22, 2022, 05:04 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 17, 2022 | Option Exercise | $232.51 | 4,114 | 956,546 | 53,623 | Feb 22, 2022, 05:03 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 18, 2022 | Sale | $231.00 | 519 | 119,889 | 53,405 | Feb 22, 2022, 05:03 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 17, 2022 | Option Exercise | $232.51 | 3,439 | 799,602 | 50,534 | Feb 22, 2022, 05:02 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 17, 2022 | Option Exercise | $232.51 | 3,497 | 813,087 | 55,578 | Feb 22, 2022, 05:01 PM |
| Liu Joy | SVP, General Counsel | Feb 17, 2022 | Option Exercise | $232.51 | 712 | 165,547 | 16,008 | Feb 22, 2022, 04:59 PM |
| LEIDEN JEFFREY M | Executive Chairman | Feb 17, 2022 | Option Exercise | $232.51 | 8,236 | 1,914,952 | 102,090 | Feb 22, 2022, 04:57 PM |
| Kewalramani Reshma | CEO & President | Feb 17, 2022 | Option Exercise | $232.51 | 8,584 | 1,995,866 | 130,088 | Feb 22, 2022, 04:56 PM |
| Bozic Carmen | EVP and CMO | Feb 17, 2022 | Option Exercise | $232.51 | 3,439 | 799,602 | 51,065 | Feb 22, 2022, 04:55 PM |
| Arbuckle Stuart A | EVP, COO | Feb 17, 2022 | Option Exercise | $232.51 | 4,126 | 959,336 | 72,312 | Feb 22, 2022, 04:54 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 17, 2022 | Option Exercise | $232.51 | 3,439 | 799,602 | 53,999 | Feb 22, 2022, 04:51 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 18, 2022 | Sale | $230.97 | 4,312 | 995,949 | 53,013 | Feb 22, 2022, 04:51 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 14, 2022 | Sale | $232.02 | 2,444 | 567,057 | 57,438 | Feb 16, 2022, 04:05 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 10, 2022 | Option Exercise | $237.74 | 2,491 | 592,210 | 59,075 | Feb 14, 2022, 04:20 PM |
| Liu Joy | SVP, General Counsel | Feb 10, 2022 | Option Exercise | $237.74 | 474 | 112,689 | 16,720 | Feb 14, 2022, 04:18 PM |
| Kewalramani Reshma | CEO & President | Feb 10, 2022 | Option Exercise | $237.74 | 3,031 | 720,590 | 138,672 | Feb 14, 2022, 04:16 PM |
| Bozic Carmen | EVP and CMO | Feb 10, 2022 | Option Exercise | $237.74 | 2,437 | 579,372 | 54,504 | Feb 14, 2022, 04:14 PM |
| Arbuckle Stuart A | EVP, COO | Feb 10, 2022 | Option Exercise | $237.74 | 3,040 | 722,730 | 76,438 | Feb 14, 2022, 04:13 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Feb 02, 2022 | Sale | $250.07 | 2,944 | 736,206 | 57,435 | Feb 03, 2022, 04:29 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 01, 2022 | Option Exercise | $243.64 | 526 | 128,155 | 55,992 | Feb 03, 2022, 04:26 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 02, 2022 | Sale | $250.98 | 1,040 | 261,017 | 55,322 | Feb 03, 2022, 04:26 PM |
| LEIDEN JEFFREY M | Executive Chairman | Feb 02, 2022 | Option Exercise | $243.63 | 6,279 | 1,529,753 | 110,326 | Feb 03, 2022, 04:19 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 02, 2022 | Option Exercise | $86.52 | 4,660 | 403,183 | 70,357 | Feb 03, 2022, 04:06 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 02, 2022 | Sale | $251.47 | 4,660 | 1,171,842 | 69,857 | Feb 03, 2022, 04:06 PM |
| MCGLYNN MARGARET G | Director | Jan 28, 2022 | Option Exercise | $127.54 | 5,000 | 637,700 | 6,099 | Feb 01, 2022, 04:09 PM |
| MCGLYNN MARGARET G | Director | Jan 28, 2022 | Sale | $241.79 | 5,000 | 1,208,960 | 4,198 | Feb 01, 2022, 04:09 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Nov 15, 2021 | Sale | $187.19 | 51 | 9,547 | 31,958 | Nov 16, 2021, 04:07 PM |
| Arbuckle Stuart A | EVP, COO | Nov 15, 2021 | Sale | $187.26 | 3 | 562 | 41,104 | Nov 16, 2021, 04:05 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 15, 2021 | Sale | $187.22 | 34 | 6,365 | 33,609 | Nov 16, 2021, 04:04 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Nov 01, 2021 | Option Exercise | $185.07 | 766 | 141,764 | 32,576 | Nov 03, 2021, 04:09 PM |
| Kewalramani Reshma | CEO & President | Aug 19, 2021 | Buy | $195.65 | 10,000 | 1,956,492 | 73,754 | Aug 23, 2021, 08:30 AM |
| SACHS BRUCE I | Director | Aug 02, 2021 | Buy | $197.91 | 15,000 | 2,968,650 | 41,210 | Aug 04, 2021, 04:05 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Jul 30, 2021 | Option Exercise | $200.39 | 766 | 153,499 | 33,342 | Aug 03, 2021, 04:10 PM |
| Bhatia Sangeeta N. | Director | Jun 02, 2021 | Sale | $209.69 | 559 | 117,216 | 5,465 | Jun 04, 2021, 04:03 PM |
| Sachdev Amit | EVP, Chief Patient Officer | May 17, 2021 | Sale | $216.35 | 45 | 9,736 | 40,170 | May 19, 2021, 04:08 PM |
| Liu Joy | SVP, General Counsel | May 17, 2021 | Sale | $216.34 | 112 | 24,230 | 8,300 | May 19, 2021, 04:06 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 17, 2021 | Sale | $216.36 | 79 | 17,093 | 33,660 | May 19, 2021, 04:02 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Apr 27, 2021 | Option Exercise | $86.52 | 3,884 | 336,044 | 44,017 | Apr 29, 2021, 04:03 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Apr 27, 2021 | Sale | $216.06 | 3,884 | 839,193 | 41,671 | Apr 29, 2021, 04:03 PM |
| Liu Joy | SVP, General Counsel | Mar 05, 2021 | Sale | $209.69 | 5,141 | 1,078,018 | 12,043 | Mar 08, 2021, 04:10 PM |
| Silva Paul M | SVP & Chief Accounting Officer | Feb 26, 2021 | Option Exercise | $212.42 | 2,218 | 471,148 | 12,666 | Mar 02, 2021, 04:07 PM |
| Silva Paul M | SVP & Chief Accounting Officer | Mar 01, 2021 | Sale | $211.45 | 2,782 | 588,255 | 11,640 | Mar 02, 2021, 04:07 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Feb 24, 2021 | Option Exercise | $217.57 | 547 | 119,011 | 35,226 | Feb 26, 2021, 04:29 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 24, 2021 | Option Exercise | $217.57 | 1,036 | 225,403 | 31,432 | Feb 26, 2021, 04:26 PM |
| Silva Paul M | SVP & Chief Accounting Officer | Feb 24, 2021 | Option Exercise | $217.57 | 864 | 187,980 | 15,964 | Feb 26, 2021, 04:23 PM |
| Silva Paul M | SVP & Chief Accounting Officer | Feb 25, 2021 | Sale | $213.47 | 1,080 | 230,552 | 15,720 | Feb 26, 2021, 04:23 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 24, 2021 | Option Exercise | $217.57 | 2,946 | 640,961 | 43,719 | Feb 26, 2021, 04:20 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 25, 2021 | Sale | $213.42 | 3,586 | 765,307 | 42,797 | Feb 26, 2021, 04:20 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Feb 24, 2021 | Option Exercise | $217.57 | 2,416 | 525,649 | 33,865 | Feb 26, 2021, 04:18 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Feb 25, 2021 | Sale | $213.38 | 3,028 | 646,125 | 33,219 | Feb 26, 2021, 04:18 PM |
| Kewalramani Reshma | CEO & President | Feb 24, 2021 | Option Exercise | $217.57 | 2,898 | 630,518 | 63,643 | Feb 26, 2021, 04:15 PM |
| Bozic Carmen | EVP and CMO | Feb 24, 2021 | Option Exercise | $217.57 | 311 | 67,664 | 33,264 | Feb 26, 2021, 04:12 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 24, 2021 | Option Exercise | $217.57 | 2,898 | 630,518 | 44,737 | Feb 26, 2021, 04:07 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 25, 2021 | Sale | $213.54 | 3,634 | 775,989 | 44,357 | Feb 26, 2021, 04:07 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 24, 2021 | Option Exercise | $217.57 | 2,416 | 525,649 | 36,617 | Feb 26, 2021, 04:03 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 25, 2021 | Sale | $213.39 | 3,028 | 646,139 | 35,971 | Feb 26, 2021, 04:03 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 17, 2021 | Option Exercise | $211.75 | 2,000 | 423,500 | 32,468 | Feb 19, 2021, 04:24 PM |
| Silva Paul M | SVP & Chief Accounting Officer | Feb 17, 2021 | Option Exercise | $211.75 | 2,740 | 580,195 | 21,123 | Feb 19, 2021, 04:21 PM |
| Silva Paul M | SVP & Chief Accounting Officer | Feb 18, 2021 | Sale | $211.83 | 4,295 | 909,828 | 20,539 | Feb 19, 2021, 04:21 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 17, 2021 | Option Exercise | $211.75 | 7,613 | 1,612,053 | 55,929 | Feb 19, 2021, 04:20 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 18, 2021 | Sale | $211.83 | 9,264 | 1,962,366 | 54,765 | Feb 19, 2021, 04:20 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Feb 17, 2021 | Option Exercise | $211.75 | 6,240 | 1,321,320 | 44,106 | Feb 19, 2021, 04:18 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Feb 18, 2021 | Sale | $211.83 | 7,825 | 1,657,556 | 43,099 | Feb 19, 2021, 04:18 PM |
| LEIDEN JEFFREY M | Executive Chairman | Feb 17, 2021 | Option Exercise | $211.75 | 13,970 | 2,958,148 | 49,676 | Feb 19, 2021, 04:15 PM |
| Kewalramani Reshma | CEO & President | Feb 17, 2021 | Option Exercise | $211.75 | 2,080 | 440,440 | 66,541 | Feb 19, 2021, 04:12 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 17, 2021 | Option Exercise | $211.75 | 6,240 | 1,321,320 | 55,460 | Feb 19, 2021, 04:08 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 18, 2021 | Sale | $211.82 | 7,825 | 1,657,481 | 54,438 | Feb 19, 2021, 04:08 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 17, 2021 | Option Exercise | $211.75 | 6,240 | 1,321,320 | 46,858 | Feb 19, 2021, 04:05 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 18, 2021 | Sale | $211.83 | 7,825 | 1,657,590 | 45,779 | Feb 19, 2021, 04:05 PM |
| Silva Paul M | SVP & Chief Accounting Officer | Feb 11, 2021 | Sale | $210.57 | 1,498 | 315,437 | 24,073 | Feb 16, 2021, 04:24 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 11, 2021 | Sale | $210.56 | 1,686 | 355,012 | 39,081 | Feb 16, 2021, 04:22 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 11, 2021 | Sale | $210.55 | 4,460 | 939,068 | 64,142 | Feb 16, 2021, 04:20 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 11, 2021 | Sale | $210.55 | 5,156 | 1,085,593 | 62,500 | Feb 16, 2021, 04:07 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 11, 2021 | Sale | $210.54 | 5,283 | 1,112,274 | 53,598 | Feb 16, 2021, 04:02 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Feb 11, 2021 | Sale | $210.56 | 4,318 | 909,179 | 50,846 | Feb 16, 2021, 12:00 AM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Feb 10, 2021 | Option Exercise | $214.16 | 2,365 | 506,488 | 35,773 | Feb 12, 2021, 04:19 PM |
| Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Feb 10, 2021 | Option Exercise | $214.16 | 1,230 | 263,417 | 34,468 | Feb 12, 2021, 04:17 PM |
| Silva Paul M | SVP & Chief Accounting Officer | Feb 10, 2021 | Option Exercise | $214.16 | 651 | 139,418 | 25,361 | Feb 12, 2021, 04:16 PM |
| Sanna Bastiano | EVP, Cell & Genetic Therapies | Feb 10, 2021 | Option Exercise | $214.16 | 1,344 | 287,831 | 40,550 | Feb 12, 2021, 04:14 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 10, 2021 | Option Exercise | $214.16 | 2,421 | 518,481 | 68,002 | Feb 12, 2021, 04:13 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Feb 10, 2021 | Option Exercise | $214.16 | 2,563 | 548,892 | 54,664 | Feb 12, 2021, 04:12 PM |
| LEIDEN JEFFREY M | Executive Chairman | Feb 10, 2021 | Option Exercise | $214.16 | 13,954 | 2,988,389 | 63,646 | Feb 12, 2021, 04:10 PM |
| Kewalramani Reshma | CEO & President | Feb 10, 2021 | Option Exercise | $214.16 | 2,962 | 634,342 | 68,621 | Feb 12, 2021, 04:07 PM |
| Bozic Carmen | EVP and CMO | Feb 10, 2021 | Option Exercise | $214.16 | 2,367 | 506,917 | 33,575 | Feb 12, 2021, 04:06 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 10, 2021 | Option Exercise | $214.16 | 3,101 | 664,110 | 66,856 | Feb 12, 2021, 04:04 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 10, 2021 | Option Exercise | $214.16 | 2,974 | 636,912 | 58,381 | Feb 12, 2021, 04:02 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Feb 05, 2021 | Option Exercise | $86.52 | 1,930 | 166,984 | 59,157 | Feb 09, 2021, 07:44 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Feb 05, 2021 | Sale | $215.00 | 1,930 | 414,950 | 57,227 | Feb 09, 2021, 07:44 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Feb 03, 2021 | Option Exercise | $86.52 | 400 | 34,608 | 57,627 | Feb 05, 2021, 04:52 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Feb 03, 2021 | Sale | $216.56 | 400 | 86,624 | 57,427 | Feb 05, 2021, 04:52 PM |
| LEIDEN JEFFREY M | Executive Chairman | Feb 03, 2021 | Option Exercise | $215.03 | 8,599 | 1,849,043 | 77,600 | Feb 05, 2021, 04:50 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 03, 2021 | Option Exercise | $86.52 | 1,554 | 134,452 | 71,511 | Feb 05, 2021, 04:43 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 03, 2021 | Sale | $213.74 | 1,554 | 332,146 | 71,363 | Feb 05, 2021, 04:43 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Nov 16, 2020 | Sale | $223.53 | 42 | 9,388 | 35,133 | Nov 18, 2020, 04:16 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Nov 16, 2020 | Sale | $223.53 | 91 | 20,341 | 26,903 | Nov 18, 2020, 04:12 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Nov 16, 2020 | Sale | $223.64 | 7 | 1,565 | 35,184 | Nov 18, 2020, 04:11 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 16, 2020 | Sale | $223.47 | 38 | 8,492 | 28,930 | Nov 18, 2020, 04:10 PM |
| SACHS BRUCE I | Director | Nov 10, 2020 | Buy | $217.36 | 15,000 | 3,260,465 | 26,210 | Nov 12, 2020, 08:18 AM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Nov 04, 2020 | Option Exercise | $86.52 | 2,330 | 201,592 | 29,168 | Nov 06, 2020, 04:09 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Nov 04, 2020 | Sale | $217.74 | 2,330 | 507,329 | 28,538 | Nov 06, 2020, 04:09 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Nov 03, 2020 | Option Exercise | $86.52 | 1,553 | 134,366 | 36,732 | Nov 05, 2020, 04:16 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Nov 03, 2020 | Sale | $211.92 | 1,553 | 329,115 | 36,245 | Nov 05, 2020, 04:16 PM |
| Bhatia Sangeeta N. | Director | Oct 05, 2020 | Option Exercise | $126.68 | 8,729 | 1,105,790 | 14,424 | Oct 07, 2020, 04:11 PM |
| Bhatia Sangeeta N. | Director | Oct 05, 2020 | Sale | $266.79 | 10,516 | 2,805,518 | 14,133 | Oct 07, 2020, 04:11 PM |
| Silva Paul M | SVP & Controller | Aug 06, 2020 | Option Exercise | $169.39 | 1,078 | 182,598 | 16,010 | Aug 10, 2020, 04:24 PM |
| Silva Paul M | SVP & Controller | Aug 06, 2020 | Sale | $271.17 | 1,078 | 292,319 | 15,590 | Aug 10, 2020, 04:24 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Aug 06, 2020 | Option Exercise | $155.57 | 1,223 | 190,262 | 28,061 | Aug 10, 2020, 04:22 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Aug 06, 2020 | Sale | $271.20 | 1,223 | 331,672 | 27,571 | Aug 10, 2020, 04:22 PM |
| Kewalramani Reshma | CEO & President | Aug 06, 2020 | Option Exercise | $179.68 | 2,073 | 372,482 | 28,699 | Aug 10, 2020, 04:19 PM |
| Kewalramani Reshma | CEO & President | Aug 06, 2020 | Sale | $271.20 | 2,073 | 562,205 | 28,547 | Aug 10, 2020, 04:19 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 06, 2020 | Option Exercise | $155.57 | 1,223 | 190,262 | 30,125 | Aug 10, 2020, 04:13 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 06, 2020 | Sale | $271.19 | 1,223 | 331,663 | 29,635 | Aug 10, 2020, 04:13 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Aug 03, 2020 | Option Exercise | $86.52 | 1,941 | 167,935 | 37,044 | Aug 05, 2020, 04:51 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Aug 03, 2020 | Sale | $278.28 | 1,941 | 540,137 | 36,544 | Aug 05, 2020, 04:51 PM |
| Silva Paul M | SVP & Controller | Aug 03, 2020 | Option Exercise | $86.52 | 809 | 69,995 | 15,741 | Aug 05, 2020, 04:24 PM |
| Silva Paul M | SVP & Controller | Aug 03, 2020 | Sale | $278.30 | 809 | 225,142 | 15,690 | Aug 05, 2020, 04:24 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Aug 03, 2020 | Option Exercise | $86.52 | 2,330 | 201,592 | 29,168 | Aug 05, 2020, 04:20 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Aug 03, 2020 | Sale | $278.28 | 2,330 | 648,402 | 28,668 | Aug 05, 2020, 04:20 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Aug 03, 2020 | Option Exercise | $86.52 | 1,553 | 134,366 | 36,732 | Aug 05, 2020, 04:17 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Aug 03, 2020 | Sale | $278.39 | 1,553 | 432,337 | 36,561 | Aug 05, 2020, 04:17 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 03, 2020 | Option Exercise | $86.52 | 2,330 | 201,592 | 31,232 | Aug 05, 2020, 04:14 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 03, 2020 | Sale | $278.24 | 2,330 | 648,290 | 30,774 | Aug 05, 2020, 04:14 PM |
| Silva Paul M | SVP & Controller | Jul 13, 2020 | Option Exercise | $90.29 | 860 | 77,649 | 15,792 | Jul 15, 2020, 04:51 PM |
| Silva Paul M | SVP & Controller | Jul 13, 2020 | Sale | $292.03 | 860 | 251,145 | 15,692 | Jul 15, 2020, 04:51 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Jul 13, 2020 | Option Exercise | $90.29 | 2,125 | 191,866 | 28,963 | Jul 15, 2020, 04:41 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Jul 13, 2020 | Sale | $292.05 | 2,125 | 620,610 | 28,863 | Jul 15, 2020, 04:41 PM |
| WAGNER CHARLES F JR | EVP & Chief Financial Officer | Jul 10, 2020 | Sale | $293.15 | 700 | 205,206 | 16,786 | Jul 14, 2020, 04:16 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Jul 07, 2020 | Option Exercise | $173.51 | 2,786 | 483,403 | 37,965 | Jul 09, 2020, 04:13 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Jul 07, 2020 | Sale | $300.00 | 2,786 | 835,800 | 35,179 | Jul 09, 2020, 04:13 PM |
| LEIDEN JEFFREY M | Executive Chairman | Jun 30, 2020 | Sale | $286.15 | 32,792 | 9,383,304 | 29,252 | Jul 02, 2020, 04:15 PM |
| Bhatia Sangeeta N. | Director | Jun 02, 2020 | Sale | $282.88 | 952 | 269,298 | 6,597 | Jun 03, 2020, 04:22 PM |
| Bozic Carmen | EVP and CMO | May 29, 2020 | Option Exercise | $282.74 | 311 | 87,932 | 13,991 | Jun 02, 2020, 04:14 PM |
| Kewalramani Reshma | CEO & President | May 15, 2020 | Sale | $284.17 | 99 | 28,132 | 26,723 | May 19, 2020, 04:35 PM |
| Tatsis Ourania | EVP, Chief Regulatory Officer | May 15, 2020 | Sale | $284.00 | 120 | 34,080 | 12,848 | May 19, 2020, 04:33 PM |
| Silva Paul M | SVP & Controller | May 15, 2020 | Sale | $284.00 | 151 | 42,885 | 15,073 | May 19, 2020, 04:31 PM |
| Sachdev Amit | EVP, Chief Patient Officer | May 15, 2020 | Sale | $284.41 | 58 | 16,496 | 35,160 | May 19, 2020, 04:29 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | May 15, 2020 | Sale | $284.40 | 68 | 19,339 | 26,905 | May 19, 2020, 04:28 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | May 15, 2020 | Sale | $283.98 | 113 | 32,089 | 35,282 | May 19, 2020, 04:22 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 15, 2020 | Sale | $284.37 | 82 | 23,318 | 28,982 | May 19, 2020, 04:21 PM |
| LEIDEN JEFFREY M | Executive Chairman | May 12, 2020 | Option Exercise | $137.52 | 88,532 | 12,174,639 | 129,353 | May 14, 2020, 04:19 PM |
| LEIDEN JEFFREY M | Executive Chairman | May 12, 2020 | Sale | $283.47 | 94,370 | 26,751,440 | 120,338 | May 14, 2020, 04:19 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 12, 2020 | Option Exercise | $187.53 | 1,304 | 244,539 | 30,206 | May 14, 2020, 04:17 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 12, 2020 | Sale | $287.33 | 1,304 | 374,678 | 28,902 | May 14, 2020, 04:17 PM |
| Sachdev Amit | EVP, Chief Patient Officer | May 11, 2020 | Option Exercise | $131.89 | 10,665 | 1,406,607 | 45,768 | May 13, 2020, 04:20 PM |
| Sachdev Amit | EVP, Chief Patient Officer | May 11, 2020 | Sale | $282.61 | 10,665 | 3,014,014 | 44,968 | May 13, 2020, 04:20 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | May 11, 2020 | Option Exercise | $187.53 | 1,304 | 244,539 | 28,142 | May 13, 2020, 04:18 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | May 11, 2020 | Sale | $286.00 | 1,304 | 372,944 | 26,838 | May 13, 2020, 04:18 PM |
| Tatsis Ourania | EVP, Chief Regulatory Officer | May 06, 2020 | Option Exercise | $174.06 | 966 | 168,146 | 13,704 | May 08, 2020, 04:28 PM |
| Tatsis Ourania | EVP, Chief Regulatory Officer | May 06, 2020 | Sale | $272.70 | 966 | 263,431 | 13,661 | May 08, 2020, 04:28 PM |
| Silva Paul M | SVP & Controller | May 06, 2020 | Option Exercise | $169.38 | 1,076 | 182,255 | 16,008 | May 08, 2020, 04:26 PM |
| Silva Paul M | SVP & Controller | May 06, 2020 | Sale | $272.74 | 1,076 | 293,472 | 15,929 | May 08, 2020, 04:26 PM |
| SACHS BRUCE I | Director | May 07, 2020 | Option Exercise | $70.55 | 45,000 | 3,174,525 | 56,210 | May 08, 2020, 04:24 PM |
| SACHS BRUCE I | Director | May 07, 2020 | Sale | $269.80 | 45,000 | 12,140,805 | 53,610 | May 08, 2020, 04:24 PM |
| Sachdev Amit | EVP, Chief Patient Officer | May 06, 2020 | Option Exercise | $131.89 | 669 | 88,234 | 35,772 | May 08, 2020, 04:23 PM |
| Sachdev Amit | EVP, Chief Patient Officer | May 06, 2020 | Sale | $275.28 | 669 | 184,162 | 35,103 | May 08, 2020, 04:23 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | May 06, 2020 | Option Exercise | $155.57 | 1,222 | 190,107 | 28,060 | May 08, 2020, 04:22 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | May 06, 2020 | Sale | $272.64 | 1,222 | 333,165 | 27,787 | May 08, 2020, 04:22 PM |
| LEIDEN JEFFREY M | Executive Chairman | May 07, 2020 | Option Exercise | $137.52 | 88,534 | 12,174,982 | 135,190 | May 08, 2020, 04:20 PM |
| LEIDEN JEFFREY M | Executive Chairman | May 07, 2020 | Sale | $269.78 | 94,369 | 25,459,013 | 129,298 | May 08, 2020, 04:20 PM |
| Kewalramani Reshma | CEO & President | May 06, 2020 | Option Exercise | $179.67 | 2,074 | 372,638 | 28,700 | May 08, 2020, 04:19 PM |
| Kewalramani Reshma | CEO & President | May 06, 2020 | Sale | $272.85 | 2,074 | 565,882 | 28,284 | May 08, 2020, 04:19 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 06, 2020 | Option Exercise | $155.57 | 1,222 | 190,107 | 30,124 | May 08, 2020, 04:17 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 06, 2020 | Sale | $272.66 | 1,222 | 333,195 | 29,853 | May 08, 2020, 04:17 PM |
| LEIDEN JEFFREY M | Executive Chairman | May 05, 2020 | Option Exercise | $137.52 | 88,537 | 12,175,273 | 141,028 | May 07, 2020, 04:24 PM |
| LEIDEN JEFFREY M | Executive Chairman | May 05, 2020 | Sale | $269.94 | 94,372 | 25,475,036 | 136,808 | May 07, 2020, 04:24 PM |
| Sachdev Amit | EVP, Chief Patient Officer | May 05, 2020 | Option Exercise | $131.89 | 13,356 | 1,761,523 | 48,459 | May 06, 2020, 04:43 PM |
| Sachdev Amit | EVP, Chief Patient Officer | May 04, 2020 | Option Exercise | $112.98 | 43,752 | 4,942,968 | 78,855 | May 06, 2020, 04:43 PM |
| Sachdev Amit | EVP, Chief Patient Officer | May 04, 2020 | Sale | $262.28 | 43,752 | 11,475,180 | 77,455 | May 06, 2020, 04:43 PM |
| Sachdev Amit | EVP, Chief Patient Officer | May 05, 2020 | Sale | $270.01 | 13,356 | 3,606,232 | 48,359 | May 06, 2020, 04:43 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | May 04, 2020 | Option Exercise | $86.52 | 1,553 | 134,366 | 36,732 | May 06, 2020, 04:38 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | May 04, 2020 | Sale | $260.76 | 1,553 | 404,957 | 36,092 | May 06, 2020, 04:38 PM |
| Silva Paul M | SVP & Controller | May 04, 2020 | Option Exercise | $86.52 | 809 | 69,995 | 15,741 | May 06, 2020, 04:27 PM |
| Silva Paul M | SVP & Controller | May 04, 2020 | Sale | $260.87 | 809 | 211,048 | 15,541 | May 06, 2020, 04:27 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | May 04, 2020 | Option Exercise | $86.52 | 2,330 | 201,592 | 29,168 | May 06, 2020, 04:25 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | May 04, 2020 | Sale | $260.87 | 2,330 | 607,827 | 28,468 | May 06, 2020, 04:25 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 04, 2020 | Option Exercise | $86.52 | 2,330 | 201,592 | 31,232 | May 06, 2020, 04:17 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 04, 2020 | Sale | $260.86 | 2,330 | 607,803 | 30,532 | May 06, 2020, 04:17 PM |
| WAGNER CHARLES F JR | EVP and CFO | Apr 30, 2020 | Option Exercise | $251.78 | 547 | 137,724 | 16,727 | May 01, 2020, 04:27 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Apr 29, 2020 | Option Exercise | $90.29 | 2,125 | 191,866 | 28,963 | May 01, 2020, 04:22 PM |
| Parini Michael | EVP, Chief Adm, Leg & BD Off | Apr 29, 2020 | Sale | $254.95 | 2,125 | 541,769 | 28,818 | May 01, 2020, 04:22 PM |
| Lee Yuchun | Director | Apr 28, 2020 | Option Exercise | $57.27 | 1,125 | 64,429 | 3,000 | Apr 29, 2020, 04:14 PM |
| Lee Yuchun | Director | Apr 28, 2020 | Sale | $257.88 | 1,125 | 290,115 | 2,800 | Apr 29, 2020, 04:14 PM |
| Lee Yuchun | Director | Apr 27, 2020 | Option Exercise | $57.27 | 2,000 | 114,540 | 3,875 | Apr 28, 2020, 04:23 PM |
| Lee Yuchun | Director | Apr 24, 2020 | Option Exercise | $57.27 | 2,000 | 114,540 | 3,875 | Apr 28, 2020, 04:23 PM |
| Lee Yuchun | Director | Apr 27, 2020 | Sale | $271.21 | 2,000 | 542,419 | 3,682 | Apr 28, 2020, 04:23 PM |
| Lee Yuchun | Director | Apr 24, 2020 | Sale | $268.14 | 2,000 | 536,286 | 2,985 | Apr 28, 2020, 04:23 PM |
| Lee Yuchun | Director | Apr 22, 2020 | Option Exercise | $57.27 | 2,000 | 114,540 | 3,875 | Apr 24, 2020, 04:17 PM |
| Lee Yuchun | Director | Apr 23, 2020 | Option Exercise | $57.27 | 2,000 | 114,540 | 3,875 | Apr 24, 2020, 04:17 PM |
| Lee Yuchun | Director | Apr 22, 2020 | Sale | $267.88 | 2,000 | 535,753 | 3,575 | Apr 24, 2020, 04:17 PM |
| Lee Yuchun | Director | Apr 23, 2020 | Sale | $272.53 | 2,000 | 545,052 | 3,522 | Apr 24, 2020, 04:17 PM |
| Lee Yuchun | Director | Apr 21, 2020 | Option Exercise | $57.27 | 2,000 | 114,540 | 3,875 | Apr 22, 2020, 04:14 PM |
| Lee Yuchun | Director | Apr 20, 2020 | Option Exercise | $57.27 | 2,000 | 114,540 | 3,875 | Apr 22, 2020, 04:14 PM |
| Lee Yuchun | Director | Apr 21, 2020 | Sale | $266.76 | 2,000 | 533,523 | 3,578 | Apr 22, 2020, 04:14 PM |
| Lee Yuchun | Director | Apr 20, 2020 | Sale | $273.16 | 2,000 | 546,310 | 3,775 | Apr 22, 2020, 04:14 PM |
| Silva Paul M | SVP & Controller | Apr 13, 2020 | Option Exercise | $90.29 | 859 | 77,559 | 15,791 | Apr 15, 2020, 04:15 PM |
| Silva Paul M | SVP & Controller | Apr 13, 2020 | Sale | $248.72 | 859 | 213,650 | 15,741 | Apr 15, 2020, 04:15 PM |
| Silva Paul M | SVP & Controller | Apr 06, 2020 | Option Exercise | $155.57 | 4,891 | 760,893 | 19,823 | Apr 08, 2020, 04:17 PM |
| Silva Paul M | SVP & Controller | Apr 06, 2020 | Sale | $255.57 | 4,891 | 1,249,993 | 14,932 | Apr 08, 2020, 04:17 PM |
| LEIDEN JEFFREY M | Executive Chairman | Mar 31, 2020 | Option Exercise | $234.01 | 40,090 | 9,381,461 | 52,491 | Apr 02, 2020, 04:16 PM |
| WAGNER CHARLES F JR | EVP and CFO | Feb 24, 2020 | Option Exercise | $239.23 | 542 | 129,663 | 17,274 | Feb 26, 2020, 04:40 PM |
| Tatsis Ourania | SVP, CRO | Feb 24, 2020 | Option Exercise | $239.23 | 1,036 | 247,842 | 14,034 | Feb 26, 2020, 04:39 PM |
| Tatsis Ourania | SVP, CRO | Feb 25, 2020 | Sale | $233.17 | 1,296 | 302,187 | 13,618 | Feb 26, 2020, 04:39 PM |
| Silva Paul M | SVP & Controller | Feb 24, 2020 | Option Exercise | $239.23 | 864 | 206,695 | 16,012 | Feb 26, 2020, 04:37 PM |
| Silva Paul M | SVP & Controller | Feb 25, 2020 | Sale | $233.45 | 1,080 | 252,127 | 15,729 | Feb 26, 2020, 04:37 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 24, 2020 | Option Exercise | $239.23 | 3,156 | 755,010 | 36,291 | Feb 26, 2020, 04:36 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 25, 2020 | Sale | $233.53 | 3,376 | 788,402 | 35,338 | Feb 26, 2020, 04:36 PM |
| Parini Michael | EVP, CL&AO | Feb 24, 2020 | Option Exercise | $239.23 | 2,416 | 577,980 | 29,866 | Feb 26, 2020, 04:35 PM |
| Parini Michael | EVP, CL&AO | Feb 25, 2020 | Sale | $233.49 | 3,028 | 707,005 | 28,928 | Feb 26, 2020, 04:35 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 24, 2020 | Option Exercise | $239.23 | 8,410 | 2,011,924 | 103,131 | Feb 26, 2020, 04:34 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 25, 2020 | Sale | $233.46 | 10,550 | 2,463,046 | 100,858 | Feb 26, 2020, 04:34 PM |
| Kewalramani Reshma | EVP and CMO | Feb 24, 2020 | Option Exercise | $239.23 | 2,898 | 693,289 | 30,260 | Feb 26, 2020, 04:32 PM |
| Kewalramani Reshma | EVP and CMO | Feb 25, 2020 | Sale | $233.45 | 3,634 | 848,371 | 29,367 | Feb 26, 2020, 04:32 PM |
| Bozic Carmen | EVP, GMDA | Feb 24, 2020 | Option Exercise | $239.23 | 216 | 51,674 | 14,302 | Feb 26, 2020, 04:31 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 24, 2020 | Option Exercise | $239.23 | 2,898 | 693,289 | 38,813 | Feb 26, 2020, 04:30 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 25, 2020 | Sale | $233.74 | 3,634 | 849,418 | 38,003 | Feb 26, 2020, 04:30 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 24, 2020 | Option Exercise | $239.23 | 2,416 | 577,980 | 31,930 | Feb 26, 2020, 04:29 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 25, 2020 | Sale | $233.41 | 3,028 | 706,776 | 31,196 | Feb 26, 2020, 04:29 PM |
| Tatsis Ourania | SVP, CRO | Feb 17, 2020 | Option Exercise | $241.50 | 597 | 144,176 | 16,349 | Feb 19, 2020, 04:39 PM |
| Tatsis Ourania | SVP, CRO | Feb 18, 2020 | Sale | $243.62 | 1,279 | 311,585 | 16,189 | Feb 19, 2020, 04:39 PM |
| Silva Paul M | SVP & Controller | Feb 17, 2020 | Option Exercise | $241.50 | 1,248 | 301,392 | 18,440 | Feb 19, 2020, 04:38 PM |
| Silva Paul M | SVP & Controller | Feb 18, 2020 | Sale | $243.58 | 1,564 | 380,957 | 18,200 | Feb 19, 2020, 04:38 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 17, 2020 | Option Exercise | $241.50 | 3,262 | 787,773 | 42,936 | Feb 19, 2020, 04:37 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 18, 2020 | Sale | $243.56 | 3,489 | 849,780 | 42,216 | Feb 19, 2020, 04:37 PM |
| Parini Michael | EVP, CL&AO | Feb 17, 2020 | Option Exercise | $241.50 | 2,496 | 602,784 | 35,410 | Feb 19, 2020, 04:36 PM |
| Parini Michael | EVP, CL&AO | Feb 18, 2020 | Sale | $243.61 | 3,128 | 762,020 | 35,050 | Feb 19, 2020, 04:36 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 17, 2020 | Option Exercise | $241.50 | 9,314 | 2,249,331 | 123,226 | Feb 19, 2020, 04:35 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 18, 2020 | Sale | $243.52 | 11,685 | 2,845,518 | 121,546 | Feb 19, 2020, 04:35 PM |
| Kewalramani Reshma | EVP and CMO | Feb 17, 2020 | Option Exercise | $241.50 | 944 | 227,976 | 34,341 | Feb 19, 2020, 04:33 PM |
| Kewalramani Reshma | EVP and CMO | Feb 18, 2020 | Sale | $243.51 | 1,183 | 288,070 | 34,221 | Feb 19, 2020, 04:33 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 17, 2020 | Option Exercise | $241.50 | 2,496 | 602,784 | 44,839 | Feb 19, 2020, 04:32 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 18, 2020 | Sale | $243.56 | 3,128 | 761,842 | 44,079 | Feb 19, 2020, 04:32 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 17, 2020 | Option Exercise | $241.50 | 2,496 | 602,784 | 37,474 | Feb 19, 2020, 04:31 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 18, 2020 | Sale | $243.67 | 3,128 | 762,201 | 37,074 | Feb 19, 2020, 04:31 PM |
| Silva Paul M | SVP & Controller | Feb 10, 2020 | Option Exercise | $240.95 | 4,673 | 1,125,959 | 25,550 | Feb 12, 2020, 05:24 PM |
| Silva Paul M | SVP & Controller | Feb 11, 2020 | Sale | $246.04 | 5,862 | 1,442,301 | 25,170 | Feb 12, 2020, 05:24 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 10, 2020 | Option Exercise | $240.95 | 12,215 | 2,943,204 | 59,268 | Feb 12, 2020, 05:22 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 11, 2020 | Sale | $246.08 | 13,070 | 3,216,311 | 58,268 | Feb 12, 2020, 05:22 PM |
| Parini Michael | EVP, CL&AO | Feb 10, 2020 | Option Exercise | $240.95 | 13,458 | 3,242,705 | 54,788 | Feb 12, 2020, 05:20 PM |
| Parini Michael | EVP, CL&AO | Feb 11, 2020 | Sale | $246.11 | 16,882 | 4,154,832 | 53,866 | Feb 12, 2020, 05:20 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 10, 2020 | Option Exercise | $240.95 | 36,755 | 8,856,117 | 180,063 | Feb 12, 2020, 05:19 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 11, 2020 | Sale | $246.09 | 47,523 | 11,694,933 | 177,263 | Feb 12, 2020, 05:19 PM |
| Lee Yuchun | Director | Feb 10, 2020 | Option Exercise | $57.27 | 1,181 | 67,636 | 3,056 | Feb 12, 2020, 05:14 PM |
| Lee Yuchun | Director | Feb 10, 2020 | Sale | $242.51 | 1,181 | 286,403 | 2,936 | Feb 12, 2020, 05:14 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 10, 2020 | Option Exercise | $240.95 | 8,942 | 2,154,575 | 58,621 | Feb 12, 2020, 05:13 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 11, 2020 | Sale | $246.09 | 11,286 | 2,777,325 | 57,691 | Feb 12, 2020, 05:13 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 10, 2020 | Option Exercise | $240.95 | 13,308 | 3,206,563 | 57,002 | Feb 12, 2020, 05:11 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 11, 2020 | Sale | $246.11 | 17,032 | 4,191,771 | 56,002 | Feb 12, 2020, 05:11 PM |
| Lee Yuchun | Director | Feb 07, 2020 | Option Exercise | $57.27 | 2,000 | 114,540 | 3,875 | Feb 11, 2020, 04:17 PM |
| Lee Yuchun | Director | Feb 07, 2020 | Sale | $237.82 | 2,000 | 475,643 | 3,575 | Feb 11, 2020, 04:17 PM |
| Lee Yuchun | Director | Feb 06, 2020 | Option Exercise | $57.27 | 2,000 | 114,540 | 3,875 | Feb 10, 2020, 04:14 PM |
| Lee Yuchun | Director | Feb 06, 2020 | Sale | $239.51 | 2,000 | 479,017 | 2,804 | Feb 10, 2020, 04:14 PM |
| Tatsis Ourania | SVP, CRO | Feb 06, 2020 | Option Exercise | $174.05 | 967 | 168,302 | 17,913 | Feb 07, 2020, 04:28 PM |
| Tatsis Ourania | SVP, CRO | Feb 06, 2020 | Sale | $239.43 | 967 | 231,527 | 17,342 | Feb 07, 2020, 04:28 PM |
| Silva Paul M | SVP & Controller | Feb 06, 2020 | Option Exercise | $187.53 | 466 | 87,389 | 30,689 | Feb 07, 2020, 04:27 PM |
| Silva Paul M | SVP & Controller | Feb 06, 2020 | Sale | $239.32 | 466 | 111,523 | 30,346 | Feb 07, 2020, 04:27 PM |
| Parini Michael | EVP, CL&AO | Feb 06, 2020 | Option Exercise | $172.06 | 2,526 | 434,614 | 70,772 | Feb 07, 2020, 04:17 PM |
| Parini Michael | EVP, CL&AO | Feb 06, 2020 | Sale | $239.42 | 2,526 | 604,783 | 69,285 | Feb 07, 2020, 04:17 PM |
| Kewalramani Reshma | EVP and CMO | Feb 06, 2020 | Option Exercise | $179.67 | 2,074 | 372,638 | 37,359 | Feb 07, 2020, 04:14 PM |
| Kewalramani Reshma | EVP and CMO | Feb 06, 2020 | Sale | $239.44 | 2,074 | 496,600 | 36,108 | Feb 07, 2020, 04:14 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 06, 2020 | Option Exercise | $173.51 | 2,787 | 483,559 | 70,350 | Feb 07, 2020, 04:08 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 06, 2020 | Sale | $239.42 | 2,787 | 667,253 | 68,839 | Feb 07, 2020, 04:08 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 06, 2020 | Option Exercise | $172.06 | 2,526 | 434,614 | 72,836 | Feb 07, 2020, 04:07 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 06, 2020 | Sale | $239.42 | 2,526 | 604,775 | 71,374 | Feb 07, 2020, 04:07 PM |
| Lee Yuchun | Director | Feb 04, 2020 | Option Exercise | $57.27 | 3,028 | 173,414 | 3,875 | Feb 06, 2020, 04:06 PM |
| Lee Yuchun | Director | Feb 05, 2020 | Option Exercise | $57.27 | 2,000 | 114,540 | 3,875 | Feb 06, 2020, 04:06 PM |
| Lee Yuchun | Director | Feb 05, 2020 | Sale | $242.38 | 2,000 | 484,763 | 3,473 | Feb 06, 2020, 04:06 PM |
| Lee Yuchun | Director | Feb 04, 2020 | Sale | $238.84 | 2,000 | 477,672 | 3,760 | Feb 06, 2020, 04:06 PM |
| Silva Paul M | SVP & Controller | Feb 03, 2020 | Option Exercise | $89.30 | 2,099 | 187,449 | 19,858 | Feb 05, 2020, 04:52 PM |
| Silva Paul M | SVP & Controller | Feb 03, 2020 | Sale | $231.03 | 2,099 | 484,939 | 19,648 | Feb 05, 2020, 04:52 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 03, 2020 | Option Exercise | $88.90 | 4,097 | 364,239 | 40,287 | Feb 05, 2020, 04:51 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Feb 03, 2020 | Sale | $231.11 | 4,097 | 946,845 | 39,787 | Feb 05, 2020, 04:51 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 03, 2020 | Option Exercise | $88.49 | 4,126 | 365,117 | 35,679 | Feb 05, 2020, 04:50 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 03, 2020 | Sale | $231.18 | 4,126 | 953,861 | 34,930 | Feb 05, 2020, 04:50 PM |
| SACHS BRUCE I | Director | Jan 31, 2020 | Option Exercise | $53.85 | 20,000 | 1,077,000 | 31,210 | Feb 04, 2020, 04:15 PM |
| SACHS BRUCE I | Director | Jan 31, 2020 | Sale | $227.99 | 20,000 | 4,559,830 | 29,510 | Feb 04, 2020, 04:15 PM |
| Parini Michael | EVP, CL&AO | Jan 31, 2020 | Option Exercise | $231.21 | 1,344 | 310,746 | 33,659 | Feb 04, 2020, 04:13 PM |
| Parini Michael | EVP, CL&AO | Jan 31, 2020 | Option Exercise | $187.53 | 3,909 | 733,055 | 38,912 | Feb 04, 2020, 04:13 PM |
| Parini Michael | EVP, CL&AO | Feb 03, 2020 | Option Exercise | $86.52 | 2,330 | 201,592 | 35,989 | Feb 04, 2020, 04:13 PM |
| Parini Michael | EVP, CL&AO | Jan 31, 2020 | Sale | $238.65 | 3,909 | 932,883 | 35,003 | Feb 04, 2020, 04:13 PM |
| Parini Michael | EVP, CL&AO | Feb 03, 2020 | Sale | $231.14 | 4,436 | 1,025,350 | 35,415 | Feb 04, 2020, 04:13 PM |
| Lee Yuchun | Director | Feb 03, 2020 | Sale | $231.10 | 2,000 | 462,196 | 2,424 | Feb 04, 2020, 04:11 PM |
| Lee Yuchun | Director | Jan 31, 2020 | Sale | $228.02 | 2,000 | 456,042 | 4,647 | Feb 04, 2020, 04:11 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Jan 31, 2020 | Option Exercise | $187.53 | 4,692 | 879,891 | 37,932 | Feb 04, 2020, 04:10 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 03, 2020 | Option Exercise | $89.15 | 3,710 | 330,756 | 36,950 | Feb 04, 2020, 04:10 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Feb 03, 2020 | Sale | $231.12 | 3,710 | 857,465 | 36,510 | Feb 04, 2020, 04:10 PM |
| Arbuckle Stuart A | EVP, Chief Commercial Officer | Jan 31, 2020 | Sale | $238.65 | 4,692 | 1,119,746 | 33,240 | Feb 04, 2020, 04:10 PM |
| Silva Paul M | SVP & Controller | Jan 31, 2020 | Option Exercise | $187.53 | 1,396 | 261,792 | 19,155 | Feb 04, 2020, 12:00 AM |
| Silva Paul M | SVP & Controller | Jan 31, 2020 | Sale | $238.65 | 1,396 | 333,155 | 17,759 | Feb 04, 2020, 12:00 AM |
| Parini Michael | EVP, CL&AO | Jan 22, 2020 | Option Exercise | $187.53 | 1 | 188 | 35,004 | Jan 24, 2020, 04:10 PM |
| Parini Michael | EVP, CL&AO | Jan 22, 2020 | Sale | $237.50 | 1 | 238 | 35,003 | Jan 24, 2020, 04:10 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Jan 16, 2020 | Option Exercise | $109.14 | 5,000 | 545,700 | 41,190 | Jan 21, 2020, 04:14 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Jan 16, 2020 | Sale | $235.00 | 5,000 | 1,175,000 | 36,190 | Jan 21, 2020, 04:14 PM |
| Silva Paul M | SVP & Controller | Jan 13, 2020 | Option Exercise | $90.29 | 860 | 77,649 | 18,619 | Jan 15, 2020, 04:09 PM |
| Silva Paul M | SVP & Controller | Jan 13, 2020 | Sale | $229.38 | 860 | 197,267 | 17,759 | Jan 15, 2020, 04:09 PM |
| Parini Michael | EVP, CL&AO | Jan 13, 2020 | Option Exercise | $90.29 | 2,125 | 191,866 | 37,128 | Jan 15, 2020, 04:08 PM |
| Parini Michael | EVP, CL&AO | Jan 13, 2020 | Sale | $226.78 | 2,125 | 481,910 | 36,828 | Jan 15, 2020, 04:08 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Jan 08, 2020 | Option Exercise | $109.14 | 5,000 | 545,700 | 41,190 | Jan 10, 2020, 04:46 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Jan 08, 2020 | Sale | $230.00 | 5,000 | 1,150,000 | 36,190 | Jan 10, 2020, 04:46 PM |
| Silva Paul M | SVP & Controller | Jan 08, 2020 | Option Exercise | $131.89 | 13,750 | 1,813,487 | 31,509 | Jan 10, 2020, 04:32 PM |
| Silva Paul M | SVP & Controller | Jan 08, 2020 | Sale | $231.89 | 13,750 | 3,188,487 | 17,759 | Jan 10, 2020, 04:32 PM |
| Tatsis Ourania | SVP, CRO | Jan 08, 2020 | Option Exercise | $187.53 | 1,675 | 314,113 | 8,927 | Jan 10, 2020, 04:22 PM |
| Tatsis Ourania | SVP, CRO | Jan 08, 2020 | Sale | $227.53 | 1,675 | 381,113 | 7,252 | Jan 10, 2020, 04:22 PM |
| Parini Michael | EVP, CL&AO | Jan 06, 2020 | Option Exercise | $122.45 | 4,250 | 520,412 | 39,253 | Jan 08, 2020, 04:11 PM |
| Parini Michael | EVP, CL&AO | Jan 06, 2020 | Sale | $222.00 | 4,250 | 943,514 | 38,853 | Jan 08, 2020, 04:11 PM |
| Silva Paul M | SVP & Controller | Jan 02, 2020 | Option Exercise | $102.37 | 25,630 | 2,623,810 | 43,389 | Jan 06, 2020, 04:17 PM |
| Silva Paul M | SVP & Controller | Jan 02, 2020 | Sale | $218.92 | 25,630 | 5,610,993 | 40,547 | Jan 06, 2020, 04:17 PM |
| YOUNG WILLIAM D | Director | Jan 02, 2020 | Option Exercise | $72.14 | 20,000 | 1,442,800 | 29,311 | Jan 06, 2020, 12:00 AM |
| YOUNG WILLIAM D | Director | Jan 02, 2020 | Sale | $218.93 | 20,000 | 4,378,696 | 26,811 | Jan 06, 2020, 12:00 AM |
| YOUNG WILLIAM D | Director | Dec 30, 2019 | Option Exercise | $65.65 | 30,000 | 1,969,500 | 39,311 | Jan 02, 2020, 04:21 PM |
| YOUNG WILLIAM D | Director | Dec 30, 2019 | Sale | $218.76 | 30,000 | 6,562,715 | 31,909 | Jan 02, 2020, 04:21 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Dec 09, 2019 | Option Exercise | $109.14 | 5,000 | 545,700 | 38,416 | Dec 10, 2019, 04:49 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Dec 09, 2019 | Sale | $225.00 | 5,000 | 1,125,000 | 33,416 | Dec 10, 2019, 04:49 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Nov 25, 2019 | Option Exercise | $109.14 | 5,000 | 545,700 | 38,416 | Nov 26, 2019, 04:13 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Nov 25, 2019 | Sale | $220.00 | 5,000 | 1,100,000 | 33,416 | Nov 26, 2019, 04:13 PM |
| Kewalramani Reshma | EVP and CMO | Nov 25, 2019 | Option Exercise | $187.53 | 4,692 | 879,891 | 17,790 | Nov 26, 2019, 04:12 PM |
| Kewalramani Reshma | EVP and CMO | Nov 25, 2019 | Sale | $219.37 | 4,692 | 1,029,284 | 13,098 | Nov 26, 2019, 04:12 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 25, 2019 | Option Exercise | $187.53 | 3,910 | 733,242 | 35,463 | Nov 26, 2019, 04:11 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 25, 2019 | Sale | $219.37 | 3,910 | 857,737 | 31,553 | Nov 26, 2019, 04:11 PM |
| LEIDEN JEFFREY M | CEO & President | Nov 19, 2019 | Option Exercise | $116.80 | 96,534 | 11,275,141 | 202,880 | Nov 21, 2019, 04:21 PM |
| LEIDEN JEFFREY M | CEO & President | Nov 19, 2019 | Sale | $210.91 | 96,534 | 20,360,052 | 139,994 | Nov 21, 2019, 04:21 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Nov 19, 2019 | Option Exercise | $109.14 | 5,000 | 545,700 | 38,416 | Nov 21, 2019, 04:19 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Nov 19, 2019 | Sale | $215.00 | 5,000 | 1,075,000 | 33,416 | Nov 21, 2019, 04:19 PM |
| Tatsis Ourania | SVP, CRO | Nov 15, 2019 | Sale | $205.95 | 5 | 1,030 | 7,252 | Nov 19, 2019, 04:17 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Nov 15, 2019 | Sale | $205.95 | 57 | 11,739 | 33,416 | Nov 19, 2019, 04:16 PM |
| Parini Michael | EVP, CL&AO | Nov 15, 2019 | Sale | $205.95 | 84 | 17,300 | 35,003 | Nov 19, 2019, 04:15 PM |
| LEIDEN JEFFREY M | CEO & President | Nov 18, 2019 | Option Exercise | $116.80 | 4,434 | 517,893 | 109,287 | Nov 19, 2019, 04:12 PM |
| LEIDEN JEFFREY M | CEO & President | Nov 15, 2019 | Option Exercise | $116.80 | 5,000 | 583,988 | 109,663 | Nov 19, 2019, 04:12 PM |
| LEIDEN JEFFREY M | CEO & President | Nov 18, 2019 | Sale | $210.00 | 4,434 | 931,140 | 106,346 | Nov 19, 2019, 04:12 PM |
| LEIDEN JEFFREY M | CEO & President | Nov 15, 2019 | Sale | $210.00 | 5,000 | 1,050,000 | 106,346 | Nov 19, 2019, 04:12 PM |
| Kewalramani Reshma | EVP and CMO | Nov 15, 2019 | Sale | $205.95 | 61 | 12,563 | 13,098 | Nov 19, 2019, 04:11 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 15, 2019 | Sale | $205.95 | 19 | 3,913 | 33,240 | Nov 19, 2019, 04:09 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 15, 2019 | Sale | $205.95 | 60 | 12,357 | 31,553 | Nov 19, 2019, 04:07 PM |
| Tatsis Ourania | SVP, CRO | Nov 13, 2019 | Option Exercise | $155.57 | 2,853 | 443,841 | 10,105 | Nov 15, 2019, 04:07 PM |
| Tatsis Ourania | SVP, CRO | Nov 13, 2019 | Sale | $205.59 | 2,853 | 586,548 | 7,252 | Nov 15, 2019, 04:07 PM |
| Parini Michael | EVP, CL&AO | Nov 13, 2019 | Option Exercise | $155.57 | 4,892 | 761,048 | 39,895 | Nov 15, 2019, 04:05 PM |
| Parini Michael | EVP, CL&AO | Nov 13, 2019 | Sale | $205.50 | 4,892 | 1,005,306 | 35,003 | Nov 15, 2019, 04:05 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 13, 2019 | Option Exercise | $155.57 | 8,560 | 1,331,679 | 41,800 | Nov 15, 2019, 04:03 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 13, 2019 | Sale | $205.57 | 8,560 | 1,759,679 | 33,240 | Nov 15, 2019, 04:03 PM |
| Kewalramani Reshma | EVP and CMO | Nov 08, 2019 | Option Exercise | $155.57 | 509 | 79,185 | 13,607 | Nov 13, 2019, 04:08 PM |
| Kewalramani Reshma | EVP and CMO | Nov 08, 2019 | Sale | $199.00 | 509 | 101,291 | 13,098 | Nov 13, 2019, 04:08 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 06, 2019 | Option Exercise | $155.57 | 1,223 | 190,262 | 32,776 | Nov 07, 2019, 04:36 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 06, 2019 | Sale | $197.21 | 1,223 | 241,189 | 32,533 | Nov 07, 2019, 04:36 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Nov 04, 2019 | Option Exercise | $88.90 | 4,097 | 364,235 | 37,513 | Nov 06, 2019, 04:15 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Nov 04, 2019 | Sale | $200.34 | 4,097 | 820,795 | 37,013 | Nov 06, 2019, 04:15 PM |
| Parini Michael | EVP, CL&AO | Nov 04, 2019 | Option Exercise | $86.52 | 2,330 | 201,592 | 37,333 | Nov 06, 2019, 04:13 PM |
| Parini Michael | EVP, CL&AO | Nov 04, 2019 | Sale | $200.50 | 2,330 | 467,168 | 35,603 | Nov 06, 2019, 04:13 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 04, 2019 | Option Exercise | $89.15 | 3,708 | 330,578 | 35,395 | Nov 06, 2019, 04:11 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 04, 2019 | Sale | $201.62 | 3,708 | 747,607 | 33,240 | Nov 06, 2019, 04:11 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 04, 2019 | Option Exercise | $88.49 | 4,126 | 365,117 | 35,679 | Nov 06, 2019, 04:10 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 04, 2019 | Sale | $200.45 | 4,126 | 827,049 | 32,353 | Nov 06, 2019, 04:10 PM |
| Kearney Terrence C | Director | Nov 01, 2019 | Option Exercise | $79.17 | 47,448 | 3,756,368 | 25,811 | Nov 04, 2019, 04:15 PM |
| Kearney Terrence C | Director | Nov 01, 2019 | Sale | $200.00 | 50,607 | 10,121,400 | 5,811 | Nov 04, 2019, 04:15 PM |
| Kearney Terrence C | Director | Oct 31, 2019 | Sale | $200.00 | 1,841 | 368,200 | 8,970 | Nov 04, 2019, 04:15 PM |
| LEIDEN JEFFREY M | CEO & President | Oct 31, 2019 | Option Exercise | $131.89 | 8,879 | 1,171,051 | 115,166 | Nov 04, 2019, 04:13 PM |
| LEIDEN JEFFREY M | CEO & President | Nov 01, 2019 | Option Exercise | $115.37 | 96,822 | 11,170,756 | 176,577 | Nov 04, 2019, 04:13 PM |
| LEIDEN JEFFREY M | CEO & President | Nov 01, 2019 | Sale | $200.02 | 96,822 | 19,365,992 | 106,287 | Nov 04, 2019, 04:13 PM |
| LEIDEN JEFFREY M | CEO & President | Oct 31, 2019 | Sale | $200.00 | 8,879 | 1,775,800 | 106,287 | Nov 04, 2019, 04:13 PM |
| Bhatia Sangeeta N. | Director | Nov 01, 2019 | Option Exercise | $152.74 | 1,291 | 197,187 | 6,540 | Nov 04, 2019, 04:11 PM |
| Bhatia Sangeeta N. | Director | Nov 01, 2019 | Sale | $200.00 | 1,291 | 258,200 | 5,249 | Nov 04, 2019, 04:11 PM |
| Kewalramani Reshma | EVP and CMO | Oct 30, 2019 | Option Exercise | $155.57 | 3,057 | 475,578 | 16,155 | Oct 31, 2019, 04:36 PM |
| Kewalramani Reshma | EVP and CMO | Oct 30, 2019 | Sale | $199.00 | 3,057 | 608,343 | 13,098 | Oct 31, 2019, 04:36 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Oct 25, 2019 | Option Exercise | $91.05 | 4,311 | 392,517 | 37,727 | Oct 29, 2019, 04:54 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Oct 25, 2019 | Sale | $195.01 | 4,311 | 840,688 | 33,416 | Oct 29, 2019, 04:54 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Oct 22, 2019 | Option Exercise | $86.52 | 3,883 | 335,957 | 37,299 | Oct 24, 2019, 07:28 PM |
| Sachdev Amit | EVP, Chief Patient Officer | Oct 22, 2019 | Sale | $190.27 | 3,883 | 738,818 | 33,416 | Oct 24, 2019, 07:28 PM |
| MCGLYNN MARGARET G | Director | Oct 22, 2019 | Option Exercise | $72.14 | 20,000 | 1,442,800 | 24,124 | Oct 24, 2019, 07:26 PM |
| MCGLYNN MARGARET G | Director | Oct 22, 2019 | Sale | $190.00 | 20,000 | 3,800,000 | 4,124 | Oct 24, 2019, 07:26 PM |
| LEIDEN JEFFREY M | CEO & President | Oct 22, 2019 | Option Exercise | $116.61 | 107,831 | 12,574,276 | 178,707 | Oct 24, 2019, 07:23 PM |
| LEIDEN JEFFREY M | CEO & President | Oct 22, 2019 | Sale | $190.00 | 107,831 | 20,487,890 | 106,287 | Oct 24, 2019, 07:23 PM |
| Kewalramani Reshma | EVP and CMO | Oct 22, 2019 | Sale | $189.00 | 638 | 120,582 | 13,098 | Oct 24, 2019, 07:18 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Oct 22, 2019 | Option Exercise | $155.57 | 3,669 | 570,786 | 35,222 | Oct 24, 2019, 07:13 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Oct 22, 2019 | Sale | $194.37 | 3,669 | 713,144 | 31,553 | Oct 24, 2019, 07:13 PM |
| Parini Michael | EVP, CL&AO | Oct 17, 2019 | Option Exercise | $122.45 | 4,250 | 520,412 | 39,253 | Oct 21, 2019, 04:29 PM |
| Parini Michael | EVP, CL&AO | Oct 17, 2019 | Sale | $177.80 | 4,250 | 755,650 | 35,003 | Oct 21, 2019, 04:29 PM |
| Parini Michael | EVP, CL&AO | Oct 14, 2019 | Option Exercise | $90.29 | 2,125 | 191,866 | 37,128 | Oct 16, 2019, 04:14 PM |
| Parini Michael | EVP, CL&AO | Oct 14, 2019 | Sale | $174.06 | 2,125 | 369,885 | 36,239 | Oct 16, 2019, 04:14 PM |
| Bhatia Sangeeta N. | Director | Oct 02, 2019 | Option Exercise | $126.51 | 7,088 | 896,676 | 13,628 | Oct 04, 2019, 04:11 PM |
| Bhatia Sangeeta N. | Director | Oct 02, 2019 | Sale | $166.80 | 8,379 | 1,397,640 | 11,668 | Oct 04, 2019, 04:11 PM |
| Tatsis Ourania | SVP, CRO | Oct 02, 2019 | Sale | $167.69 | 444 | 74,454 | 7,252 | Oct 03, 2019, 04:25 PM |
| Tatsis Ourania | SVP, CRO | Oct 01, 2019 | Sale | $169.11 | 188 | 31,793 | 7,696 | Oct 03, 2019, 04:25 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 19, 2019 | Option Exercise | $103.25 | 12,501 | 1,290,681 | 36,212 | Aug 20, 2019, 04:30 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 19, 2019 | Sale | $186.38 | 12,501 | 2,329,976 | 33,883 | Aug 20, 2019, 04:30 PM |
| MCGLYNN MARGARET G | Director | Aug 13, 2019 | Option Exercise | $81.54 | 10,000 | 815,400 | 14,124 | Aug 15, 2019, 04:11 PM |
| MCGLYNN MARGARET G | Director | Aug 13, 2019 | Sale | $185.00 | 10,000 | 1,850,000 | 4,124 | Aug 15, 2019, 04:11 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 08, 2019 | Option Exercise | $131.89 | 2,125 | 280,266 | 35,365 | Aug 12, 2019, 04:14 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 08, 2019 | Sale | $181.89 | 2,125 | 386,516 | 33,240 | Aug 12, 2019, 04:14 PM |
| Parini Michael | EVP, CL&AO | Aug 05, 2019 | Option Exercise | $86.52 | 2,330 | 201,592 | 37,333 | Aug 06, 2019, 04:43 PM |
| Parini Michael | EVP, CL&AO | Aug 05, 2019 | Sale | $175.28 | 2,330 | 408,399 | 36,633 | Aug 06, 2019, 04:43 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 05, 2019 | Option Exercise | $86.52 | 1,553 | 134,366 | 33,793 | Aug 06, 2019, 04:41 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 02, 2019 | Option Exercise | $91.05 | 2,155 | 196,213 | 34,395 | Aug 06, 2019, 04:41 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 05, 2019 | Sale | $176.44 | 1,553 | 274,011 | 32,240 | Aug 06, 2019, 04:41 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 02, 2019 | Sale | $177.78 | 2,155 | 383,116 | 32,240 | Aug 06, 2019, 04:41 PM |
| Parini Michael | EVP, CL&AO | Jul 12, 2019 | Option Exercise | $90.29 | 2,125 | 191,866 | 37,128 | Jul 15, 2019, 04:15 PM |
| Parini Michael | EVP, CL&AO | Jul 12, 2019 | Sale | $175.27 | 2,125 | 372,455 | 35,610 | Jul 15, 2019, 04:15 PM |
| Parini Michael | EVP, CL&AO | Jul 05, 2019 | Option Exercise | $122.45 | 4,250 | 520,412 | 39,253 | Jul 09, 2019, 04:49 PM |
| Parini Michael | EVP, CL&AO | Jul 05, 2019 | Sale | $179.11 | 4,250 | 761,238 | 36,803 | Jul 09, 2019, 04:49 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jun 19, 2019 | Option Exercise | $131.89 | 2,125 | 280,266 | 35,365 | Jun 20, 2019, 04:53 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jun 19, 2019 | Sale | $181.89 | 2,125 | 386,516 | 33,240 | Jun 20, 2019, 04:53 PM |
| LEIDEN JEFFREY M | CEO & President | Jun 18, 2019 | Option Exercise | $77.31 | 56,030 | 4,331,679 | 162,317 | Jun 20, 2019, 04:43 PM |
| LEIDEN JEFFREY M | CEO & President | Jun 18, 2019 | Sale | $175.39 | 56,030 | 9,827,054 | 110,536 | Jun 20, 2019, 04:43 PM |
| Bhatia Sangeeta N. | Director | Jun 03, 2019 | Sale | $167.08 | 720 | 120,298 | 6,860 | Jun 04, 2019, 04:08 PM |
| LEIDEN JEFFREY M | CEO & President | May 24, 2019 | Option Exercise | $77.31 | 113,432 | 8,769,428 | 219,719 | May 28, 2019, 05:45 PM |
| LEIDEN JEFFREY M | CEO & President | May 24, 2019 | Sale | $175.10 | 113,432 | 19,861,944 | 106,287 | May 28, 2019, 05:45 PM |
| Sachdev Amit | EVP, CRO | May 15, 2019 | Sale | $165.41 | 61 | 10,090 | 33,416 | May 17, 2019, 04:37 PM |
| Silva Paul M | SVP & Controller | May 15, 2019 | Sale | $165.41 | 161 | 26,631 | 17,759 | May 17, 2019, 04:31 PM |
| Parini Michael | EVP, CL&AO | May 15, 2019 | Sale | $165.41 | 83 | 13,729 | 35,003 | May 17, 2019, 04:29 PM |
| Kewalramani Reshma | EVP and CMO | May 15, 2019 | Sale | $165.41 | 241 | 39,864 | 13,736 | May 17, 2019, 04:21 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | May 15, 2019 | Sale | $165.41 | 133 | 22,000 | 33,240 | May 17, 2019, 04:18 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 15, 2019 | Sale | $165.41 | 91 | 15,052 | 31,553 | May 17, 2019, 04:16 PM |
| LEIDEN JEFFREY M | CEO & President | May 06, 2019 | Option Exercise | $77.31 | 33,058 | 2,555,714 | 136,953 | May 08, 2019, 04:10 PM |
| LEIDEN JEFFREY M | CEO & President | May 06, 2019 | Sale | $175.01 | 33,058 | 5,785,503 | 106,195 | May 08, 2019, 04:10 PM |
| Parini Michael | EVP, CL&AO | May 03, 2019 | Option Exercise | $86.52 | 2,329 | 201,505 | 37,332 | May 06, 2019, 04:08 PM |
| Parini Michael | EVP, CL&AO | May 03, 2019 | Sale | $172.06 | 1,622 | 279,074 | 36,832 | May 06, 2019, 04:08 PM |
| Parini Michael | EVP, CL&AO | May 30, 2019 | Sale | $173.00 | 707 | 122,311 | 35,625 | May 06, 2019, 04:08 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | May 03, 2019 | Option Exercise | $86.52 | 1,553 | 134,366 | 34,793 | May 06, 2019, 04:06 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | May 02, 2019 | Option Exercise | $91.05 | 2,155 | 196,213 | 35,395 | May 06, 2019, 04:06 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | May 03, 2019 | Sale | $172.39 | 1,553 | 267,723 | 34,553 | May 06, 2019, 04:06 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | May 02, 2019 | Sale | $169.27 | 2,155 | 364,768 | 34,197 | May 06, 2019, 04:06 PM |
| LEIDEN JEFFREY M | CEO & President | May 01, 2019 | Option Exercise | $77.31 | 10,480 | 810,209 | 116,375 | May 03, 2019, 04:06 PM |
| LEIDEN JEFFREY M | CEO & President | May 01, 2019 | Sale | $175.08 | 10,480 | 1,834,826 | 106,195 | May 03, 2019, 04:06 PM |
| Parini Michael | EVP, CL&AO | Apr 16, 2019 | Option Exercise | $111.73 | 6,375 | 712,279 | 39,253 | Apr 18, 2019, 04:12 PM |
| Parini Michael | EVP, CL&AO | Apr 16, 2019 | Sale | $181.99 | 6,375 | 1,160,166 | 38,383 | Apr 18, 2019, 04:12 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Apr 15, 2019 | Sale | $181.75 | 5,624 | 1,022,148 | 36,272 | Apr 17, 2019, 04:30 PM |
| Silva Paul M | SVP & Interim CFO | Feb 19, 2019 | Sale | $186.97 | 2,812 | 525,747 | 18,903 | Feb 21, 2019, 04:27 PM |
| Parini Michael | EVP, CL&AO | Feb 19, 2019 | Sale | $186.98 | 5,624 | 1,051,585 | 36,003 | Feb 21, 2019, 04:26 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 19, 2019 | Sale | $186.98 | 20,997 | 3,926,113 | 110,095 | Feb 21, 2019, 04:24 PM |
| Kewalramani Reshma | EVP and CMO | Feb 19, 2019 | Sale | $186.94 | 1,488 | 278,163 | 14,038 | Feb 21, 2019, 04:22 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 19, 2019 | Sale | $187.00 | 5,624 | 1,051,716 | 32,604 | Feb 21, 2019, 04:21 PM |
| Sachdev Amit | EVP, CRO | Feb 11, 2019 | Sale | $180.06 | 35,095 | 6,319,216 | 64,692 | Feb 13, 2019, 04:40 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 11, 2019 | Sale | $180.24 | 111,431 | 20,083,803 | 223,916 | Feb 13, 2019, 04:39 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 11, 2019 | Sale | $180.21 | 33,073 | 5,959,969 | 61,280 | Feb 13, 2019, 04:37 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 11, 2019 | Sale | $180.22 | 32,956 | 5,939,188 | 60,050 | Feb 13, 2019, 04:36 PM |
| Parini Michael | EVP, CL&AO | Feb 11, 2019 | Sale | $180.22 | 12,136 | 2,187,190 | 48,869 | Feb 13, 2019, 04:33 PM |
| Silva Paul M | SVP & Interim CFO | Feb 11, 2019 | Sale | $180.16 | 4,215 | 759,367 | 23,386 | Feb 13, 2019, 04:27 PM |
| Silva Paul M | SVP & Interim CFO | Feb 06, 2019 | Option Exercise | $91.05 | 1,289 | 117,363 | 13,938 | Feb 07, 2019, 04:04 PM |
| Silva Paul M | SVP & Interim CFO | Feb 06, 2019 | Sale | $193.00 | 1,289 | 248,777 | 12,649 | Feb 07, 2019, 04:04 PM |
| Sachdev Amit | EVP, CRO | Feb 04, 2019 | Option Exercise | $88.90 | 4,097 | 364,235 | 48,817 | Feb 06, 2019, 04:51 PM |
| Sachdev Amit | EVP, CRO | Feb 04, 2019 | Sale | $186.86 | 12,722 | 2,377,296 | 47,697 | Feb 06, 2019, 04:51 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 04, 2019 | Option Exercise | $99.97 | 7,959 | 795,657 | 54,711 | Feb 06, 2019, 04:50 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 04, 2019 | Sale | $186.20 | 18,309 | 3,409,083 | 53,311 | Feb 06, 2019, 04:50 PM |
| Silva Paul M | SVP & Interim CFO | Feb 04, 2019 | Option Exercise | $86.52 | 809 | 69,995 | 16,896 | Feb 06, 2019, 04:49 PM |
| Silva Paul M | SVP & Interim CFO | Feb 04, 2019 | Sale | $187.02 | 4,247 | 794,273 | 16,087 | Feb 06, 2019, 04:49 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 04, 2019 | Sale | $186.35 | 32,250 | 6,009,682 | 155,815 | Feb 06, 2019, 04:47 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 04, 2019 | Option Exercise | $88.49 | 4,126 | 365,117 | 41,443 | Feb 06, 2019, 04:46 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 04, 2019 | Sale | $189.19 | 4,126 | 780,598 | 39,113 | Feb 06, 2019, 04:46 PM |
| Parini Michael | EVP, CL&AO | Feb 04, 2019 | Option Exercise | $86.52 | 2,330 | 201,592 | 38,489 | Feb 06, 2019, 04:45 PM |
| Parini Michael | EVP, CL&AO | Feb 04, 2019 | Sale | $189.19 | 2,330 | 440,813 | 36,159 | Feb 06, 2019, 04:45 PM |
| Parini Michael | EVP, CL&AO | Feb 01, 2019 | Sale | $190.92 | 3,450 | 658,674 | 36,159 | Feb 04, 2019, 04:05 PM |
| Parini Michael | EVP, CL&AO | Jan 22, 2019 | Option Exercise | $155.57 | 3,668 | 570,631 | 43,277 | Jan 24, 2019, 04:47 PM |
| Parini Michael | EVP, CL&AO | Jan 22, 2019 | Sale | $195.00 | 3,668 | 715,260 | 39,609 | Jan 24, 2019, 04:47 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jan 22, 2019 | Option Exercise | $131.89 | 2,125 | 280,266 | 48,877 | Jan 24, 2019, 04:46 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jan 22, 2019 | Sale | $193.48 | 2,125 | 411,145 | 46,752 | Jan 24, 2019, 04:46 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jan 22, 2019 | Option Exercise | $131.89 | 2,125 | 280,266 | 41,238 | Jan 24, 2019, 04:45 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jan 22, 2019 | Sale | $193.48 | 2,125 | 411,145 | 39,113 | Jan 24, 2019, 04:45 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jan 18, 2019 | Option Exercise | $155.70 | 1,223 | 190,421 | 40,336 | Jan 22, 2019, 04:07 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jan 18, 2019 | Sale | $194.62 | 1,223 | 238,020 | 39,113 | Jan 22, 2019, 04:07 PM |
| Silva Paul M | SVP & Corp Controller | Jan 17, 2019 | Option Exercise | $90.62 | 3,007 | 272,482 | 17,376 | Jan 18, 2019, 04:18 PM |
| Silva Paul M | SVP & Corp Controller | Jan 17, 2019 | Sale | $190.62 | 3,007 | 573,182 | 16,087 | Jan 18, 2019, 04:18 PM |
| Parini Michael | EVP, CL&AO | Jan 14, 2019 | Option Exercise | $90.29 | 2,125 | 191,866 | 41,734 | Jan 15, 2019, 04:03 PM |
| Parini Michael | EVP, CL&AO | Jan 14, 2019 | Sale | $186.71 | 2,125 | 396,759 | 39,609 | Jan 15, 2019, 04:03 PM |
| Parini Michael | EVP, CL&AO | Jan 04, 2019 | Option Exercise | $122.45 | 4,250 | 520,412 | 43,859 | Jan 07, 2019, 04:02 PM |
| Parini Michael | EVP, CL&AO | Jan 04, 2019 | Sale | $165.90 | 4,250 | 705,075 | 39,609 | Jan 07, 2019, 04:02 PM |
| SACHS BRUCE I | Director | Dec 06, 2018 | Option Exercise | $34.24 | 10,000 | 342,400 | 23,011 | Dec 07, 2018, 04:06 PM |
| Silva Paul M | SVP & Corp Controller | Dec 03, 2018 | Option Exercise | $86.52 | 809 | 69,995 | 16,896 | Dec 04, 2018, 04:04 PM |
| Silva Paul M | SVP & Corp Controller | Dec 03, 2018 | Sale | $186.52 | 809 | 150,895 | 16,087 | Dec 04, 2018, 04:04 PM |
| Silva Paul M | SVP & Corp Controller | Nov 15, 2018 | Sale | $163.75 | 12 | 1,965 | 16,087 | Nov 19, 2018, 05:52 PM |
| Parini Michael | EVP, CL&AO | Nov 15, 2018 | Sale | $163.75 | 90 | 14,738 | 39,609 | Nov 19, 2018, 05:47 PM |
| Sachdev Amit | EVP, CRO | Nov 15, 2018 | Sale | $163.75 | 61 | 9,989 | 46,662 | Nov 19, 2018, 05:34 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 15, 2018 | Sale | $163.75 | 29 | 4,749 | 46,752 | Nov 19, 2018, 05:28 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 15, 2018 | Sale | $163.75 | 100 | 16,375 | 39,113 | Nov 19, 2018, 05:23 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 07, 2018 | Option Exercise | $131.89 | 2,125 | 280,266 | 48,877 | Nov 08, 2018, 04:26 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 07, 2018 | Sale | $179.00 | 2,125 | 380,375 | 46,752 | Nov 08, 2018, 04:26 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 07, 2018 | Option Exercise | $131.89 | 2,125 | 280,266 | 41,238 | Nov 08, 2018, 04:18 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 07, 2018 | Sale | $181.89 | 2,125 | 386,516 | 39,113 | Nov 08, 2018, 04:18 PM |
| Sachdev Amit | EVP, CRO | Nov 05, 2018 | Option Exercise | $86.52 | 1,941 | 167,935 | 48,603 | Nov 06, 2018, 04:45 PM |
| Sachdev Amit | EVP, CRO | Nov 02, 2018 | Option Exercise | $91.05 | 2,155 | 196,213 | 48,817 | Nov 06, 2018, 04:45 PM |
| Sachdev Amit | EVP, CRO | Nov 05, 2018 | Sale | $173.73 | 1,941 | 337,204 | 48,303 | Nov 06, 2018, 04:45 PM |
| Sachdev Amit | EVP, CRO | Nov 02, 2018 | Sale | $172.86 | 2,155 | 372,505 | 48,217 | Nov 06, 2018, 04:45 PM |
| Parini Michael | EVP, CL&AO | Nov 05, 2018 | Option Exercise | $86.52 | 2,330 | 201,592 | 41,939 | Nov 06, 2018, 04:32 PM |
| Parini Michael | EVP, CL&AO | Nov 05, 2018 | Sale | $172.08 | 2,330 | 400,946 | 39,609 | Nov 06, 2018, 04:32 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 05, 2018 | Option Exercise | $103.09 | 5,803 | 598,211 | 51,002 | Nov 06, 2018, 04:24 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 05, 2018 | Sale | $172.08 | 5,803 | 998,580 | 46,752 | Nov 06, 2018, 04:24 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 02, 2018 | Option Exercise | $91.05 | 1,796 | 163,526 | 40,909 | Nov 06, 2018, 04:11 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 05, 2018 | Option Exercise | $86.52 | 2,330 | 201,592 | 41,443 | Nov 06, 2018, 04:11 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 02, 2018 | Sale | $175.36 | 1,796 | 314,947 | 39,113 | Nov 06, 2018, 04:11 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 05, 2018 | Sale | $172.08 | 2,330 | 400,946 | 39,113 | Nov 06, 2018, 04:11 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 02, 2018 | Option Exercise | $91.05 | 2,155 | 196,213 | 48,907 | Nov 05, 2018, 04:52 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 02, 2018 | Sale | $175.36 | 2,155 | 377,901 | 46,752 | Nov 05, 2018, 04:52 PM |
| Parini Michael | EVP, CL&AO | Oct 12, 2018 | Option Exercise | $90.29 | 2,125 | 191,866 | 41,734 | Oct 16, 2018, 04:29 PM |
| Parini Michael | EVP, CL&AO | Oct 12, 2018 | Sale | $177.20 | 2,125 | 376,550 | 39,609 | Oct 16, 2018, 04:29 PM |
| Kewalramani Reshma | EVP and CMO | Oct 08, 2018 | Sale | $186.95 | 2,305 | 430,920 | 1,909 | Oct 09, 2018, 04:50 PM |
| Parini Michael | EVP, CL&AO | Oct 04, 2018 | Option Exercise | $122.45 | 4,250 | 520,412 | 43,859 | Oct 05, 2018, 05:35 PM |
| Parini Michael | EVP, CL&AO | Oct 04, 2018 | Sale | $191.58 | 4,250 | 814,215 | 39,609 | Oct 05, 2018, 05:35 PM |
| Bhatia Sangeeta N. | Director | Oct 03, 2018 | Option Exercise | $126.38 | 6,818 | 861,650 | 9,579 | Oct 05, 2018, 05:28 PM |
| Bhatia Sangeeta N. | Director | Oct 03, 2018 | Sale | $192.13 | 6,818 | 1,309,942 | 4,879 | Oct 05, 2018, 05:28 PM |
| Graney Thomas | Chief Financial Officer | Oct 01, 2018 | Sale | $193.24 | 1,076 | 207,926 | 12,430 | Oct 02, 2018, 04:24 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Oct 01, 2018 | Option Exercise | $155.57 | 2,445 | 380,369 | 41,558 | Oct 02, 2018, 12:00 AM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Oct 01, 2018 | Sale | $194.62 | 2,445 | 475,846 | 39,113 | Oct 02, 2018, 12:00 AM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 28, 2018 | Option Exercise | $131.89 | 2,125 | 280,266 | 41,238 | Aug 30, 2018, 04:07 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 28, 2018 | Sale | $181.89 | 2,125 | 386,516 | 39,113 | Aug 30, 2018, 04:07 PM |
| Parini Michael | EVP, CL&AO | Aug 03, 2018 | Option Exercise | $86.52 | 2,330 | 201,592 | 41,939 | Aug 07, 2018, 04:46 PM |
| Parini Michael | EVP, CL&AO | Aug 03, 2018 | Sale | $174.20 | 2,330 | 405,886 | 39,609 | Aug 07, 2018, 04:46 PM |
| Sachdev Amit | EVP, CRO | Aug 02, 2018 | Option Exercise | $91.05 | 2,155 | 196,213 | 48,817 | Aug 06, 2018, 06:19 PM |
| Sachdev Amit | EVP, CRO | Aug 03, 2018 | Option Exercise | $86.52 | 1,942 | 168,022 | 48,604 | Aug 06, 2018, 06:19 PM |
| Sachdev Amit | EVP, CRO | Aug 03, 2018 | Sale | $175.10 | 1,942 | 340,050 | 47,462 | Aug 06, 2018, 06:19 PM |
| Sachdev Amit | EVP, CRO | Aug 02, 2018 | Sale | $176.73 | 2,155 | 380,852 | 48,117 | Aug 06, 2018, 06:19 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 03, 2018 | Option Exercise | $86.52 | 2,330 | 201,592 | 41,443 | Aug 06, 2018, 05:42 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 02, 2018 | Option Exercise | $91.05 | 1,796 | 163,526 | 40,909 | Aug 06, 2018, 05:42 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 03, 2018 | Sale | $174.20 | 2,330 | 405,886 | 39,113 | Aug 06, 2018, 05:42 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 02, 2018 | Sale | $174.59 | 1,796 | 313,564 | 39,113 | Aug 06, 2018, 05:42 PM |
| Silva Paul M | SVP & Corp Controller | Aug 03, 2018 | Option Exercise | $86.52 | 809 | 69,995 | 16,896 | Aug 06, 2018, 05:38 PM |
| Silva Paul M | SVP & Corp Controller | Aug 02, 2018 | Option Exercise | $91.05 | 1,289 | 117,363 | 17,376 | Aug 06, 2018, 05:38 PM |
| Silva Paul M | SVP & Corp Controller | Aug 03, 2018 | Sale | $174.20 | 809 | 140,928 | 16,087 | Aug 06, 2018, 05:38 PM |
| Silva Paul M | SVP & Corp Controller | Aug 02, 2018 | Sale | $174.59 | 1,289 | 225,047 | 16,087 | Aug 06, 2018, 05:38 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 03, 2018 | Option Exercise | $103.09 | 5,803 | 598,211 | 52,555 | Aug 06, 2018, 05:21 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 02, 2018 | Option Exercise | $111.33 | 4,280 | 476,479 | 48,907 | Aug 06, 2018, 05:21 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 02, 2018 | Sale | $176.78 | 4,280 | 756,616 | 46,752 | Aug 06, 2018, 05:21 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 03, 2018 | Sale | $174.20 | 5,803 | 1,010,883 | 46,752 | Aug 06, 2018, 05:21 PM |
| Silva Paul M | SVP & Corp Controller | Jul 16, 2018 | Option Exercise | $96.87 | 860 | 83,308 | 16,947 | Jul 18, 2018, 05:44 PM |
| Silva Paul M | SVP & Corp Controller | Jul 16, 2018 | Sale | $179.85 | 860 | 154,671 | 16,087 | Jul 18, 2018, 05:44 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jul 16, 2018 | Option Exercise | $131.89 | 23,375 | 3,082,929 | 62,488 | Jul 18, 2018, 05:32 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jul 16, 2018 | Sale | $182.00 | 23,375 | 4,254,250 | 39,113 | Jul 18, 2018, 05:32 PM |
| Sachdev Amit | EVP, CRO | Jul 13, 2018 | Option Exercise | $96.87 | 12,031 | 1,165,443 | 58,693 | Jul 17, 2018, 06:30 PM |
| Sachdev Amit | EVP, CRO | Jul 16, 2018 | Option Exercise | $96.87 | 1,719 | 166,520 | 48,381 | Jul 17, 2018, 06:30 PM |
| Sachdev Amit | EVP, CRO | Jul 16, 2018 | Sale | $180.36 | 1,719 | 310,042 | 46,881 | Jul 17, 2018, 06:30 PM |
| Sachdev Amit | EVP, CRO | Jul 13, 2018 | Sale | $180.00 | 12,031 | 2,165,580 | 46,662 | Jul 17, 2018, 06:30 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jul 16, 2018 | Option Exercise | $96.87 | 2,125 | 205,849 | 48,877 | Jul 17, 2018, 06:23 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jul 13, 2018 | Option Exercise | $131.89 | 6,375 | 840,799 | 53,127 | Jul 17, 2018, 06:23 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jul 16, 2018 | Sale | $179.85 | 2,125 | 382,181 | 46,752 | Jul 17, 2018, 06:23 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jul 13, 2018 | Sale | $179.00 | 6,375 | 1,141,125 | 46,752 | Jul 17, 2018, 06:23 PM |
| Parini Michael | EVP, CL&AO | Jul 12, 2018 | Option Exercise | $90.29 | 2,125 | 191,866 | 41,734 | Jul 16, 2018, 04:37 PM |
| Parini Michael | EVP, CL&AO | Jul 12, 2018 | Sale | $175.02 | 2,125 | 371,918 | 39,609 | Jul 16, 2018, 04:37 PM |
| Silva Paul M | SVP & Corp Controller | Jul 12, 2018 | Option Exercise | $90.29 | 860 | 77,649 | 16,947 | Jul 16, 2018, 04:19 PM |
| Silva Paul M | SVP & Corp Controller | Jul 12, 2018 | Sale | $175.02 | 860 | 150,517 | 16,087 | Jul 16, 2018, 04:19 PM |
| Parini Michael | EVP, CL&AO | Jul 05, 2018 | Option Exercise | $122.45 | 4,250 | 520,412 | 43,859 | Jul 09, 2018, 06:14 PM |
| Parini Michael | EVP, CL&AO | Jul 05, 2018 | Sale | $168.38 | 4,250 | 715,615 | 39,609 | Jul 09, 2018, 06:14 PM |
| SMITH IAN F | EVP, COO | Jun 29, 2018 | Option Exercise | $131.89 | 23,375 | 3,082,929 | 70,074 | Jul 03, 2018, 04:25 PM |
| SMITH IAN F | EVP, COO | Jun 29, 2018 | Sale | $166.30 | 23,375 | 3,887,174 | 65,333 | Jul 03, 2018, 04:25 PM |
| Silva Paul M | SVP & Corp Controller | Jun 29, 2018 | Option Exercise | $91.50 | 2,957 | 270,569 | 17,376 | Jul 03, 2018, 04:16 PM |
| Silva Paul M | SVP & Corp Controller | Jun 29, 2018 | Sale | $166.52 | 2,957 | 492,385 | 16,087 | Jul 03, 2018, 04:16 PM |
| Sachdev Amit | EVP, CRO | Jun 29, 2018 | Option Exercise | $88.90 | 4,096 | 364,148 | 50,758 | Jul 03, 2018, 04:12 PM |
| Sachdev Amit | EVP, CRO | Jun 29, 2018 | Sale | $167.63 | 4,096 | 686,615 | 48,817 | Jul 03, 2018, 04:12 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jun 29, 2018 | Option Exercise | $87.13 | 13,445 | 1,171,397 | 83,444 | Jul 03, 2018, 12:00 AM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jun 29, 2018 | Option Exercise | $89.15 | 3,708 | 330,578 | 50,460 | Jul 03, 2018, 12:00 AM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jun 29, 2018 | Sale | $164.98 | 44,331 | 7,313,596 | 75,909 | Jul 03, 2018, 12:00 AM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jun 29, 2018 | Sale | $169.00 | 3,708 | 626,652 | 46,752 | Jul 03, 2018, 12:00 AM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jun 22, 2018 | Option Exercise | $109.14 | 4,250 | 463,845 | 51,002 | Jun 26, 2018, 05:20 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jun 22, 2018 | Sale | $159.00 | 4,250 | 675,750 | 46,752 | Jun 26, 2018, 05:20 PM |
| SMITH IAN F | EVP, COO | Jun 22, 2018 | Option Exercise | $109.14 | 4,250 | 463,845 | 50,949 | Jun 26, 2018, 05:18 PM |
| SMITH IAN F | EVP, COO | Jun 22, 2018 | Sale | $160.00 | 4,250 | 680,000 | 46,699 | Jun 26, 2018, 05:18 PM |
| LEIDEN JEFFREY M | CEO & President | Jun 22, 2018 | Option Exercise | $83.36 | 106,500 | 8,877,840 | 297,260 | Jun 26, 2018, 05:18 PM |
| LEIDEN JEFFREY M | CEO & President | Jun 22, 2018 | Sale | $160.00 | 140,211 | 22,433,760 | 157,049 | Jun 26, 2018, 05:18 PM |
| Bhatia Sangeeta N. | Director | Jun 04, 2018 | Sale | $152.05 | 875 | 133,044 | 4,879 | Jun 05, 2018, 05:39 PM |
| Silva Paul M | SVP & Corp Controller | May 15, 2018 | Sale | $155.78 | 201 | 31,312 | 16,087 | May 16, 2018, 05:27 PM |
| Parini Michael | EVP, CL&AO | May 15, 2018 | Sale | $155.78 | 85 | 13,241 | 39,609 | May 16, 2018, 05:24 PM |
| SMITH IAN F | EVP, COO | May 15, 2018 | Sale | $155.78 | 217 | 33,804 | 46,699 | May 16, 2018, 05:21 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | May 15, 2018 | Sale | $155.78 | 138 | 21,498 | 46,752 | May 16, 2018, 05:11 PM |
| Sachdev Amit | EVP, CRO | May 15, 2018 | Sale | $155.78 | 83 | 12,930 | 46,662 | May 16, 2018, 05:06 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 15, 2018 | Sale | $155.78 | 98 | 15,266 | 69,999 | May 16, 2018, 04:48 PM |
| SMITH IAN F | EVP, COO | May 11, 2018 | Option Exercise | $88.90 | 4,096 | 364,148 | 50,795 | May 15, 2018, 04:21 PM |
| SMITH IAN F | EVP, COO | May 11, 2018 | Sale | $155.00 | 4,096 | 634,880 | 46,699 | May 15, 2018, 04:21 PM |
| Parini Michael | EVP, CL&AO | May 03, 2018 | Option Exercise | $86.52 | 2,330 | 201,592 | 41,939 | May 04, 2018, 04:23 PM |
| Parini Michael | EVP, CL&AO | May 03, 2018 | Sale | $149.50 | 2,330 | 348,335 | 39,609 | May 04, 2018, 04:23 PM |
| Parini Michael | EVP, CL&AO | Apr 26, 2018 | Option Exercise | $122.45 | 38,250 | 4,683,712 | 77,859 | Apr 27, 2018, 04:38 PM |
| Parini Michael | EVP, CL&AO | Apr 25, 2018 | Option Exercise | $90.29 | 2,125 | 191,866 | 42,123 | Apr 27, 2018, 04:38 PM |
| Parini Michael | EVP, CL&AO | Apr 26, 2018 | Sale | $159.56 | 38,250 | 6,103,170 | 39,609 | Apr 27, 2018, 04:38 PM |
| Parini Michael | EVP, CL&AO | Apr 25, 2018 | Sale | $155.22 | 2,514 | 390,233 | 39,909 | Apr 27, 2018, 04:38 PM |
| SMITH IAN F | EVP, COO | Apr 25, 2018 | Option Exercise | $84.45 | 14,172 | 1,196,786 | 78,667 | Apr 27, 2018, 04:37 PM |
| SMITH IAN F | EVP, COO | Apr 26, 2018 | Option Exercise | $108.65 | 53,125 | 5,771,989 | 99,824 | Apr 27, 2018, 04:37 PM |
| SMITH IAN F | EVP, COO | Apr 26, 2018 | Sale | $160.12 | 53,125 | 8,506,375 | 46,699 | Apr 27, 2018, 04:37 PM |
| SMITH IAN F | EVP, COO | Apr 25, 2018 | Sale | $155.33 | 31,968 | 4,965,526 | 59,189 | Apr 27, 2018, 04:37 PM |
| Silva Paul M | SVP & Corp Controller | Apr 18, 2018 | Option Exercise | $90.29 | 859 | 77,559 | 16,946 | Apr 19, 2018, 05:37 PM |
| Silva Paul M | SVP & Corp Controller | Apr 18, 2018 | Sale | $166.05 | 859 | 142,637 | 16,087 | Apr 19, 2018, 05:37 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Apr 16, 2018 | Option Exercise | $96.87 | 2,125 | 205,849 | 48,877 | Apr 18, 2018, 02:50 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Apr 16, 2018 | Sale | $163.01 | 2,125 | 346,396 | 46,752 | Apr 18, 2018, 02:50 PM |
| Silva Paul M | SVP & Corp Controller | Apr 02, 2018 | Sale | $161.21 | 3,438 | 554,249 | 16,225 | Apr 04, 2018, 05:07 PM |
| Sachdev Amit | EVP, CRO | Mar 09, 2018 | Option Exercise | $96.87 | 13,750 | 1,331,963 | 60,412 | Mar 12, 2018, 05:36 PM |
| Sachdev Amit | EVP, CRO | Mar 09, 2018 | Sale | $175.00 | 13,750 | 2,406,250 | 46,662 | Mar 12, 2018, 05:36 PM |
| MCGLYNN MARGARET G | Director | Mar 02, 2018 | Option Exercise | $81.54 | 10,000 | 815,400 | 16,312 | Mar 05, 2018, 06:13 PM |
| MCGLYNN MARGARET G | Director | Mar 02, 2018 | Sale | $170.00 | 10,000 | 1,700,000 | 6,312 | Mar 05, 2018, 06:13 PM |
| Sachdev Amit | EVP, CRO | Feb 26, 2018 | Option Exercise | $91.05 | 2,155 | 196,213 | 48,817 | Feb 28, 2018, 09:30 AM |
| Sachdev Amit | EVP, CRO | Feb 26, 2018 | Sale | $170.00 | 2,155 | 366,350 | 46,662 | Feb 28, 2018, 09:30 AM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 26, 2018 | Option Exercise | $86.52 | 1,554 | 134,452 | 53,211 | Feb 28, 2018, 09:22 AM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 26, 2018 | Sale | $169.00 | 6,459 | 1,091,571 | 46,752 | Feb 28, 2018, 09:22 AM |
| Silva Paul M | SVP & Corp Controller | Feb 20, 2018 | Sale | $158.49 | 3,437 | 544,730 | 19,525 | Feb 21, 2018, 06:16 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 13, 2018 | Sale | $151.83 | 4,044 | 614,000 | 53,679 | Feb 15, 2018, 04:23 PM |
| Sachdev Amit | EVP, CRO | Feb 12, 2018 | Sale | $150.84 | 17,796 | 2,684,411 | 59,958 | Feb 14, 2018, 06:23 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 12, 2018 | Sale | $152.82 | 6,824 | 1,042,833 | 61,650 | Feb 14, 2018, 06:16 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Feb 12, 2018 | Sale | $150.82 | 5,122 | 772,493 | 73,485 | Feb 14, 2018, 06:15 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 12, 2018 | Sale | $150.83 | 23,905 | 3,605,547 | 208,463 | Feb 14, 2018, 06:06 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 12, 2018 | Sale | $150.82 | 6,403 | 965,671 | 74,652 | Feb 14, 2018, 05:53 PM |
| Parini Michael | EVP, CL&AO | Feb 12, 2018 | Sale | $153.41 | 12,136 | 1,861,784 | 39,998 | Feb 14, 2018, 05:39 PM |
| Silva Paul M | SVP & Corp Controller | Feb 12, 2018 | Sale | $153.41 | 4,213 | 646,316 | 22,962 | Feb 14, 2018, 05:23 PM |
| Sachdev Amit | EVP, CRO | Feb 05, 2018 | Option Exercise | $81.27 | 4,520 | 367,327 | 43,683 | Feb 07, 2018, 06:26 PM |
| Sachdev Amit | EVP, CRO | Feb 05, 2018 | Sale | $163.01 | 4,520 | 736,800 | 43,305 | Feb 07, 2018, 06:26 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Feb 05, 2018 | Option Exercise | $109.14 | 3,594 | 392,249 | 56,118 | Feb 07, 2018, 06:16 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Feb 05, 2018 | Sale | $161.46 | 3,594 | 580,304 | 55,624 | Feb 07, 2018, 06:16 PM |
| Parini Michael | EVP, CL&AO | Feb 05, 2018 | Option Exercise | $86.52 | 2,330 | 201,592 | 27,823 | Feb 07, 2018, 05:56 PM |
| Parini Michael | EVP, CL&AO | Feb 05, 2018 | Sale | $163.08 | 2,330 | 379,976 | 25,493 | Feb 07, 2018, 05:56 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 05, 2018 | Option Exercise | $93.22 | 8,500 | 792,412 | 50,452 | Feb 07, 2018, 05:46 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 05, 2018 | Sale | $163.08 | 8,500 | 1,386,180 | 41,952 | Feb 07, 2018, 05:46 PM |
| Silva Paul M | SVP & Corp Controller | Feb 05, 2018 | Option Exercise | $80.86 | 2,098 | 169,647 | 18,732 | Feb 07, 2018, 05:37 PM |
| Silva Paul M | SVP & Corp Controller | Feb 05, 2018 | Sale | $163.08 | 2,098 | 342,142 | 16,634 | Feb 07, 2018, 05:37 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 02, 2018 | Option Exercise | $91.05 | 1,796 | 163,526 | 51,557 | Feb 05, 2018, 05:47 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 02, 2018 | Sale | $166.11 | 1,796 | 298,330 | 50,957 | Feb 05, 2018, 05:47 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Feb 02, 2018 | Option Exercise | $91.05 | 1,796 | 163,526 | 54,320 | Feb 05, 2018, 05:43 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Feb 01, 2018 | Sale | $167.44 | 1,900 | 318,136 | 52,524 | Feb 05, 2018, 05:43 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Feb 02, 2018 | Sale | $166.11 | 1,796 | 298,329 | 53,720 | Feb 05, 2018, 05:43 PM |
| Silva Paul M | SVP & Corp Controller | Feb 02, 2018 | Option Exercise | $91.05 | 1,289 | 117,363 | 17,923 | Feb 05, 2018, 05:39 PM |
| Silva Paul M | SVP & Corp Controller | Feb 01, 2018 | Option Exercise | $96.87 | 8,594 | 832,501 | 25,228 | Feb 05, 2018, 05:39 PM |
| Silva Paul M | SVP & Corp Controller | Feb 02, 2018 | Sale | $169.42 | 1,289 | 218,382 | 16,634 | Feb 05, 2018, 05:39 PM |
| Silva Paul M | SVP & Corp Controller | Feb 01, 2018 | Sale | $174.11 | 8,594 | 1,496,301 | 16,634 | Feb 05, 2018, 05:39 PM |
| Parini Michael | EVP, CL&AO | Feb 01, 2018 | Sale | $174.11 | 3,450 | 600,680 | 25,493 | Feb 05, 2018, 05:35 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 02, 2018 | Option Exercise | $91.05 | 2,156 | 196,304 | 44,108 | Feb 05, 2018, 05:11 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 02, 2018 | Sale | $169.42 | 2,156 | 365,270 | 41,952 | Feb 05, 2018, 05:11 PM |
| Sachdev Amit | EVP, CRO | Jan 29, 2018 | Option Exercise | $91.05 | 15,085 | 1,373,489 | 54,248 | Jan 30, 2018, 05:10 PM |
| Sachdev Amit | EVP, CRO | Jan 29, 2018 | Sale | $170.00 | 15,085 | 2,564,450 | 39,163 | Jan 30, 2018, 05:10 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jan 24, 2018 | Option Exercise | $88.70 | 8,969 | 795,522 | 50,921 | Jan 26, 2018, 04:46 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jan 24, 2018 | Sale | $169.00 | 8,969 | 1,515,761 | 41,952 | Jan 26, 2018, 04:46 PM |
| Sachdev Amit | EVP, CRO | Jan 23, 2018 | Option Exercise | $86.52 | 5,824 | 503,892 | 44,987 | Jan 25, 2018, 06:33 PM |
| Sachdev Amit | EVP, CRO | Jan 23, 2018 | Sale | $165.00 | 5,824 | 960,960 | 39,163 | Jan 25, 2018, 06:33 PM |
| MCGLYNN MARGARET G | Director | Jan 23, 2018 | Option Exercise | $59.55 | 10,000 | 595,500 | 16,217 | Jan 24, 2018, 05:35 PM |
| MCGLYNN MARGARET G | Director | Jan 22, 2018 | Option Exercise | $59.55 | 10,000 | 595,500 | 16,217 | Jan 24, 2018, 05:35 PM |
| MCGLYNN MARGARET G | Director | Jan 23, 2018 | Sale | $165.00 | 10,000 | 1,650,000 | 6,217 | Jan 24, 2018, 05:35 PM |
| MCGLYNN MARGARET G | Director | Jan 22, 2018 | Sale | $160.00 | 10,000 | 1,600,000 | 6,217 | Jan 24, 2018, 05:35 PM |
| Silva Paul M | SVP & Corp Controller | Jan 22, 2018 | Option Exercise | $86.52 | 2,427 | 209,984 | 19,061 | Jan 24, 2018, 05:33 PM |
| Silva Paul M | SVP & Corp Controller | Jan 23, 2018 | Option Exercise | $90.62 | 3,008 | 272,572 | 19,642 | Jan 24, 2018, 05:33 PM |
| Silva Paul M | SVP & Corp Controller | Jan 23, 2018 | Sale | $166.05 | 3,008 | 499,478 | 16,634 | Jan 24, 2018, 05:33 PM |
| Silva Paul M | SVP & Corp Controller | Jan 22, 2018 | Sale | $161.52 | 2,427 | 392,009 | 16,634 | Jan 24, 2018, 05:33 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jan 22, 2018 | Option Exercise | $91.05 | 1,796 | 163,526 | 51,557 | Jan 24, 2018, 05:29 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jan 22, 2018 | Sale | $160.00 | 1,796 | 287,360 | 49,761 | Jan 24, 2018, 05:29 PM |
| Sachdev Amit | EVP, CRO | Jan 19, 2018 | Option Exercise | $79.88 | 32,422 | 2,589,732 | 71,585 | Jan 23, 2018, 04:56 PM |
| Sachdev Amit | EVP, CRO | Jan 22, 2018 | Option Exercise | $83.36 | 13,750 | 1,146,200 | 52,913 | Jan 23, 2018, 04:56 PM |
| Sachdev Amit | EVP, CRO | Jan 19, 2018 | Sale | $158.08 | 32,422 | 5,125,400 | 53,175 | Jan 23, 2018, 04:56 PM |
| Sachdev Amit | EVP, CRO | Jan 22, 2018 | Sale | $160.00 | 13,750 | 2,200,000 | 39,163 | Jan 23, 2018, 04:56 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jan 16, 2018 | Sale | $156.99 | 56,250 | 8,830,755 | 82,198 | Jan 17, 2018, 04:46 PM |
| LEIDEN JEFFREY M | CEO & President | Jan 16, 2018 | Option Exercise | $46.72 | 99,563 | 4,651,915 | 232,060 | Jan 17, 2018, 04:45 PM |
| LEIDEN JEFFREY M | CEO & President | Jan 16, 2018 | Sale | $156.99 | 99,563 | 15,630,614 | 189,689 | Jan 17, 2018, 04:45 PM |
| SMITH IAN F | EVP, COO | Jan 16, 2018 | Option Exercise | $96.87 | 2,125 | 205,849 | 43,013 | Jan 17, 2018, 04:40 PM |
| SMITH IAN F | EVP, COO | Jan 16, 2018 | Sale | $157.29 | 2,125 | 334,232 | 42,188 | Jan 17, 2018, 04:40 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jan 16, 2018 | Option Exercise | $96.87 | 1,719 | 166,520 | 56,143 | Jan 17, 2018, 04:38 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jan 16, 2018 | Sale | $157.28 | 1,719 | 270,358 | 55,624 | Jan 17, 2018, 04:38 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jan 16, 2018 | Option Exercise | $96.87 | 2,125 | 205,849 | 44,077 | Jan 17, 2018, 04:34 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jan 16, 2018 | Sale | $158.28 | 2,125 | 336,345 | 41,952 | Jan 17, 2018, 04:34 PM |
| Parini Michael | EVP, CL&AO | Jan 12, 2018 | Option Exercise | $90.29 | 2,125 | 191,866 | 31,068 | Jan 16, 2018, 05:01 PM |
| Parini Michael | EVP, CL&AO | Jan 12, 2018 | Sale | $157.16 | 2,125 | 333,965 | 28,943 | Jan 16, 2018, 05:01 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jan 11, 2018 | Option Exercise | $109.14 | 4,250 | 463,845 | 46,202 | Jan 12, 2018, 04:16 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jan 11, 2018 | Sale | $159.00 | 4,250 | 675,750 | 41,952 | Jan 12, 2018, 04:16 PM |
| Bhatia Sangeeta N. | Director | Jan 05, 2018 | Option Exercise | $126.68 | 10,753 | 1,362,190 | 14,706 | Jan 09, 2018, 05:33 PM |
| Bhatia Sangeeta N. | Director | Jan 05, 2018 | Sale | $156.00 | 10,753 | 1,677,468 | 3,953 | Jan 09, 2018, 05:33 PM |
| Graney Thomas | Chief Financial Officer | Jan 02, 2018 | Sale | $149.95 | 777 | 116,511 | 8,789 | Jan 03, 2018, 04:49 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jan 02, 2018 | Option Exercise | $73.51 | 3,438 | 252,727 | 57,862 | Jan 03, 2018, 12:00 AM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jan 02, 2018 | Sale | $151.80 | 3,438 | 521,895 | 57,562 | Jan 03, 2018, 12:00 AM |
| Silva Paul M | SVP & Corp Controller | Dec 27, 2017 | Option Exercise | $77.31 | 1,289 | 99,653 | 17,923 | Dec 28, 2017, 04:31 PM |
| Silva Paul M | SVP & Corp Controller | Dec 27, 2017 | Sale | $152.31 | 1,289 | 196,328 | 16,634 | Dec 28, 2017, 04:31 PM |
| LEIDEN JEFFREY M | CEO & President | Dec 11, 2017 | Sale | $141.35 | 125,000 | 17,668,896 | 237,407 | Dec 11, 2017, 06:30 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 15, 2017 | Sale | $147.29 | 48 | 7,070 | 41,952 | Dec 06, 2017, 05:40 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Nov 15, 2017 | Sale | $149.12 | 306 | 45,630 | 106,217 | Nov 17, 2017, 04:48 PM |
| Silva Paul M | SVP & Corp Controller | Nov 15, 2017 | Sale | $147.29 | 23 | 3,388 | 16,634 | Nov 17, 2017, 04:46 PM |
| SMITH IAN F | EVP, COO | Nov 15, 2017 | Sale | $147.29 | 7 | 1,031 | 40,888 | Nov 17, 2017, 04:44 PM |
| Sachdev Amit | EVP, CRO | Nov 15, 2017 | Sale | $147.29 | 83 | 12,225 | 50,710 | Nov 17, 2017, 04:41 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 15, 2017 | Sale | $147.29 | 221 | 32,551 | 41,952 | Nov 17, 2017, 04:37 PM |
| SMITH IAN F | EVP, COO | Nov 06, 2017 | Option Exercise | $77.31 | 4,250 | 328,567 | 45,138 | Nov 07, 2017, 05:26 PM |
| SMITH IAN F | EVP, COO | Nov 03, 2017 | Option Exercise | $91.05 | 2,155 | 196,213 | 43,043 | Nov 07, 2017, 05:26 PM |
| SMITH IAN F | EVP, COO | Nov 06, 2017 | Sale | $150.00 | 4,250 | 637,500 | 40,888 | Nov 07, 2017, 05:26 PM |
| SMITH IAN F | EVP, COO | Nov 03, 2017 | Sale | $150.00 | 2,155 | 323,250 | 40,888 | Nov 07, 2017, 05:26 PM |
| Parini Michael | EVP, CL&AO | Nov 03, 2017 | Option Exercise | $86.52 | 2,330 | 201,592 | 31,139 | Nov 07, 2017, 05:23 PM |
| Parini Michael | EVP, CL&AO | Nov 03, 2017 | Sale | $149.50 | 2,330 | 348,335 | 28,809 | Nov 07, 2017, 05:23 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 06, 2017 | Option Exercise | $77.31 | 4,250 | 328,567 | 46,202 | Nov 07, 2017, 05:15 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 06, 2017 | Sale | $148.17 | 4,250 | 629,722 | 41,952 | Nov 07, 2017, 05:15 PM |
| Bhatia Sangeeta N. | Director | Nov 03, 2017 | Option Exercise | $93.51 | 7,073 | 661,396 | 11,026 | Nov 07, 2017, 05:12 PM |
| Bhatia Sangeeta N. | Director | Nov 03, 2017 | Sale | $143.05 | 7,073 | 1,011,793 | 3,953 | Nov 07, 2017, 05:12 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Nov 03, 2017 | Option Exercise | $109.14 | 3,594 | 392,249 | 58,018 | Nov 06, 2017, 05:50 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Nov 02, 2017 | Option Exercise | $91.05 | 1,796 | 163,526 | 56,220 | Nov 06, 2017, 05:50 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Nov 02, 2017 | Sale | $144.76 | 1,796 | 259,982 | 55,820 | Nov 06, 2017, 05:50 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Nov 03, 2017 | Sale | $144.69 | 3,594 | 520,016 | 54,424 | Nov 06, 2017, 05:50 PM |
| SMITH IAN F | EVP, COO | Oct 31, 2017 | Sale | $145.06 | 75,000 | 10,879,858 | 114,188 | Oct 31, 2017, 06:18 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Oct 27, 2017 | Option Exercise | $96.87 | 2,125 | 205,849 | 119,077 | Oct 31, 2017, 06:16 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Oct 31, 2017 | Sale | $144.81 | 75,000 | 10,860,645 | 105,335 | Oct 31, 2017, 06:16 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Oct 27, 2017 | Sale | $143.97 | 6,290 | 905,598 | 116,952 | Oct 31, 2017, 06:16 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Oct 31, 2017 | Sale | $145.05 | 60,000 | 8,703,161 | 113,024 | Oct 31, 2017, 06:15 PM |
| Sachdev Amit | EVP, CRO | Oct 31, 2017 | Sale | $145.05 | 40,000 | 5,802,084 | 89,810 | Oct 31, 2017, 06:12 PM |
| SMITH IAN F | EVP, COO | Oct 16, 2017 | Option Exercise | $96.87 | 2,125 | 205,849 | 118,013 | Oct 18, 2017, 05:41 PM |
| SMITH IAN F | EVP, COO | Oct 16, 2017 | Sale | $155.61 | 2,125 | 330,671 | 117,813 | Oct 18, 2017, 05:41 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Oct 16, 2017 | Option Exercise | $96.87 | 1,718 | 166,423 | 116,142 | Oct 18, 2017, 05:35 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Oct 16, 2017 | Sale | $155.19 | 1,718 | 266,610 | 115,842 | Oct 18, 2017, 05:35 PM |
| Parini Michael | EVP, CL&AO | Oct 12, 2017 | Option Exercise | $90.29 | 2,125 | 191,866 | 30,934 | Oct 16, 2017, 04:59 PM |
| Parini Michael | EVP, CL&AO | Oct 12, 2017 | Sale | $152.93 | 2,125 | 324,976 | 28,809 | Oct 16, 2017, 04:59 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Oct 02, 2017 | Option Exercise | $73.51 | 3,437 | 252,654 | 117,861 | Oct 04, 2017, 05:01 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Oct 02, 2017 | Sale | $151.64 | 3,437 | 521,198 | 116,467 | Oct 04, 2017, 05:01 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 31, 2017 | Option Exercise | $91.05 | 1,796 | 163,526 | 107,807 | Sep 05, 2017, 04:42 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Aug 31, 2017 | Sale | $160.00 | 1,796 | 287,360 | 106,011 | Sep 05, 2017, 04:42 PM |
| Silva Paul M | SVP & Corp Controller | Aug 07, 2017 | Option Exercise | $77.31 | 1,289 | 99,653 | 17,923 | Aug 09, 2017, 04:38 PM |
| Silva Paul M | SVP & Corp Controller | Aug 07, 2017 | Sale | $152.88 | 1,289 | 197,062 | 16,634 | Aug 09, 2017, 04:38 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 07, 2017 | Option Exercise | $77.31 | 4,250 | 328,567 | 125,367 | Aug 09, 2017, 04:36 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 07, 2017 | Sale | $152.88 | 4,250 | 649,740 | 121,117 | Aug 09, 2017, 04:36 PM |
| SMITH IAN F | EVP, CFO & COO | Aug 07, 2017 | Option Exercise | $77.31 | 4,250 | 328,567 | 120,138 | Aug 09, 2017, 04:33 PM |
| SMITH IAN F | EVP, CFO & COO | Aug 07, 2017 | Sale | $155.39 | 4,250 | 660,415 | 119,738 | Aug 09, 2017, 04:33 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 03, 2017 | Option Exercise | $109.14 | 4,250 | 463,845 | 125,367 | Aug 04, 2017, 04:53 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Aug 03, 2017 | Sale | $155.72 | 4,250 | 661,810 | 121,117 | Aug 04, 2017, 04:53 PM |
| SMITH IAN F | EVP, CFO & COO | Aug 02, 2017 | Option Exercise | $91.05 | 2,155 | 196,213 | 118,043 | Aug 04, 2017, 04:48 PM |
| SMITH IAN F | EVP, CFO & COO | Aug 02, 2017 | Sale | $154.17 | 2,155 | 332,236 | 117,543 | Aug 04, 2017, 04:48 PM |
| Parini Michael | EVP, CL&AO | Aug 03, 2017 | Option Exercise | $86.52 | 2,330 | 201,592 | 31,139 | Aug 04, 2017, 04:45 PM |
| Parini Michael | EVP, CL&AO | Aug 03, 2017 | Sale | $155.72 | 2,330 | 362,828 | 28,809 | Aug 04, 2017, 04:45 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Aug 03, 2017 | Option Exercise | $109.14 | 3,594 | 392,249 | 118,018 | Aug 04, 2017, 04:42 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Aug 02, 2017 | Option Exercise | $91.05 | 1,796 | 163,526 | 116,220 | Aug 04, 2017, 04:42 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Aug 03, 2017 | Sale | $154.19 | 3,594 | 554,149 | 117,418 | Aug 04, 2017, 04:42 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Aug 02, 2017 | Sale | $154.13 | 1,796 | 276,811 | 115,720 | Aug 04, 2017, 04:42 PM |
| Silva Paul M | SVP & Corp Controller | Aug 02, 2017 | Option Exercise | $91.05 | 1,289 | 117,363 | 17,923 | Aug 04, 2017, 04:36 PM |
| Silva Paul M | SVP & Corp Controller | Aug 02, 2017 | Sale | $151.80 | 1,289 | 195,670 | 16,634 | Aug 04, 2017, 04:36 PM |
| LEIDEN JEFFREY M | CEO & President | Jul 31, 2017 | Option Exercise | $45.11 | 11,063 | 499,052 | 268,455 | Aug 02, 2017, 04:56 PM |
| LEIDEN JEFFREY M | CEO & President | Jul 31, 2017 | Sale | $152.81 | 11,063 | 1,690,552 | 263,092 | Aug 02, 2017, 04:56 PM |
| SMITH IAN F | EVP, CFO & COO | Jul 31, 2017 | Option Exercise | $83.36 | 2,125 | 177,140 | 118,013 | Aug 02, 2017, 04:51 PM |
| SMITH IAN F | EVP, CFO & COO | Jul 31, 2017 | Sale | $152.88 | 2,125 | 324,865 | 117,088 | Aug 02, 2017, 04:51 PM |
| Silva Paul M | SVP & Corp Controller | Jul 31, 2017 | Option Exercise | $83.36 | 860 | 71,690 | 17,494 | Aug 02, 2017, 04:47 PM |
| Silva Paul M | SVP & Corp Controller | Jul 31, 2017 | Sale | $152.99 | 860 | 131,571 | 16,634 | Aug 02, 2017, 04:47 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jul 31, 2017 | Option Exercise | $83.36 | 2,125 | 177,140 | 123,242 | Aug 02, 2017, 04:44 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jul 31, 2017 | Sale | $152.99 | 2,125 | 325,104 | 121,117 | Aug 02, 2017, 04:44 PM |
| Silva Paul M | SVP & Corp Controller | Jul 19, 2017 | Option Exercise | $75.91 | 40,006 | 3,036,870 | 60,077 | Jul 21, 2017, 08:10 PM |
| Silva Paul M | SVP & Corp Controller | Jul 19, 2017 | Sale | $161.00 | 40,006 | 6,440,966 | 20,071 | Jul 21, 2017, 08:10 PM |
| Silva Paul M | SVP & Corp Controller | Jul 21, 2017 | Sale | $161.91 | 3,437 | 556,490 | 17,134 | Jul 21, 2017, 08:10 PM |
| SMITH IAN F | EVP, CFO & COO | Jul 19, 2017 | Option Exercise | $84.11 | 123,400 | 10,379,726 | 249,638 | Jul 21, 2017, 08:09 PM |
| SMITH IAN F | EVP, CFO & COO | Jul 21, 2017 | Sale | $160.72 | 10,350 | 1,663,413 | 125,838 | Jul 21, 2017, 08:09 PM |
| SMITH IAN F | EVP, CFO & COO | Jul 19, 2017 | Sale | $161.00 | 123,400 | 19,867,400 | 126,238 | Jul 21, 2017, 08:09 PM |
| Sachdev Amit | EVP, CRO | Jul 19, 2017 | Option Exercise | $77.31 | 20,000 | 1,546,200 | 119,335 | Jul 21, 2017, 08:07 PM |
| Sachdev Amit | EVP, CRO | Jul 21, 2017 | Sale | $160.78 | 8,625 | 1,386,691 | 98,535 | Jul 21, 2017, 08:07 PM |
| Sachdev Amit | EVP, CRO | Jul 19, 2017 | Sale | $161.00 | 20,000 | 3,220,000 | 99,335 | Jul 21, 2017, 08:07 PM |
| Parini Michael | EVP, CL&AO | Jul 19, 2017 | Option Exercise | $89.48 | 10,829 | 968,970 | 39,638 | Jul 21, 2017, 08:05 PM |
| Parini Michael | EVP, CL&AO | Jul 19, 2017 | Sale | $161.00 | 10,829 | 1,743,469 | 28,809 | Jul 21, 2017, 08:05 PM |
| LEIDEN JEFFREY M | CEO & President | Jul 19, 2017 | Option Exercise | $46.56 | 184,374 | 8,584,824 | 474,016 | Jul 21, 2017, 08:04 PM |
| LEIDEN JEFFREY M | CEO & President | Jul 21, 2017 | Sale | $160.74 | 32,250 | 5,184,008 | 288,942 | Jul 21, 2017, 08:04 PM |
| LEIDEN JEFFREY M | CEO & President | Jul 19, 2017 | Sale | $161.00 | 184,374 | 29,684,214 | 289,642 | Jul 21, 2017, 08:04 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jul 19, 2017 | Option Exercise | $107.14 | 38,646 | 4,140,487 | 161,157 | Jul 21, 2017, 08:02 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jul 21, 2017 | Sale | $160.73 | 6,900 | 1,109,022 | 120,624 | Jul 21, 2017, 08:02 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jul 19, 2017 | Sale | $161.00 | 39,833 | 6,413,113 | 121,324 | Jul 21, 2017, 08:02 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jul 19, 2017 | Option Exercise | $84.49 | 28,979 | 2,448,338 | 134,990 | Jul 21, 2017, 08:00 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jul 19, 2017 | Sale | $161.00 | 28,979 | 4,665,619 | 106,011 | Jul 21, 2017, 08:00 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jul 21, 2017 | Option Exercise | $131.89 | 2,125 | 280,266 | 133,592 | Jul 21, 2017, 07:58 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jul 19, 2017 | Option Exercise | $107.25 | 89,400 | 9,587,718 | 220,867 | Jul 21, 2017, 07:58 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jul 19, 2017 | Sale | $161.54 | 89,400 | 14,441,830 | 160,467 | Jul 21, 2017, 07:58 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jul 21, 2017 | Sale | $161.22 | 12,475 | 2,011,271 | 131,467 | Jul 21, 2017, 07:58 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jul 17, 2017 | Option Exercise | $96.87 | 573 | 55,507 | 123,084 | Jul 19, 2017, 04:45 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jul 17, 2017 | Sale | $129.85 | 573 | 74,402 | 122,611 | Jul 19, 2017, 04:45 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jul 03, 2017 | Option Exercise | $73.51 | 3,438 | 252,727 | 125,949 | Jul 06, 2017, 04:45 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jul 03, 2017 | Sale | $127.80 | 3,438 | 439,379 | 123,727 | Jul 06, 2017, 04:45 PM |
| Silva Paul M | SVP & Corp Controller | Jun 21, 2017 | Option Exercise | $83.36 | 2,577 | 214,819 | 22,648 | Jun 23, 2017, 04:10 PM |
| Silva Paul M | SVP & Corp Controller | Jun 21, 2017 | Sale | $133.36 | 2,577 | 343,669 | 20,071 | Jun 23, 2017, 04:10 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jun 21, 2017 | Option Exercise | $96.87 | 5,157 | 499,559 | 127,668 | Jun 23, 2017, 04:08 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jun 21, 2017 | Sale | $132.87 | 5,157 | 685,211 | 122,511 | Jun 23, 2017, 04:08 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jun 05, 2017 | Option Exercise | $72.14 | 7,500 | 541,050 | 113,511 | Jun 05, 2017, 06:10 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Jun 05, 2017 | Sale | $130.00 | 7,500 | 975,000 | 106,011 | Jun 05, 2017, 06:10 PM |
| Silva Paul M | SVP & Corp Controller | Jun 01, 2017 | Option Exercise | $77.31 | 3,867 | 298,958 | 23,938 | Jun 05, 2017, 06:09 PM |
| Silva Paul M | SVP & Corp Controller | Jun 01, 2017 | Sale | $127.31 | 3,867 | 492,308 | 20,071 | Jun 05, 2017, 06:09 PM |
| Sachdev Amit | EVP, CRO | Jun 01, 2017 | Option Exercise | $51.75 | 30,500 | 1,578,375 | 129,835 | Jun 05, 2017, 06:08 PM |
| Sachdev Amit | EVP, CRO | Jun 01, 2017 | Sale | $125.00 | 30,500 | 3,812,500 | 99,335 | Jun 05, 2017, 06:08 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jun 01, 2017 | Option Exercise | $96.87 | 5,155 | 499,365 | 127,666 | Jun 05, 2017, 06:07 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Jun 01, 2017 | Sale | $126.87 | 5,155 | 654,015 | 122,511 | Jun 05, 2017, 06:07 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jun 01, 2017 | Option Exercise | $53.74 | 13,594 | 730,542 | 145,061 | Jun 05, 2017, 06:06 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jun 02, 2017 | Option Exercise | $80.67 | 57,375 | 4,628,505 | 188,842 | Jun 05, 2017, 06:06 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jun 01, 2017 | Sale | $124.00 | 13,594 | 1,685,656 | 131,467 | Jun 05, 2017, 06:06 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Jun 02, 2017 | Sale | $129.02 | 57,375 | 7,402,523 | 131,467 | Jun 05, 2017, 06:06 PM |
| SMITH IAN F | EVP, CFO & COO | Jun 01, 2017 | Option Exercise | $43.99 | 98,553 | 4,334,887 | 224,791 | Jun 05, 2017, 06:05 PM |
| SMITH IAN F | EVP, CFO & COO | Jun 01, 2017 | Sale | $124.00 | 98,553 | 12,220,572 | 126,238 | Jun 05, 2017, 06:05 PM |
| LEIDEN JEFFREY M | CEO & President | Jun 02, 2017 | Option Exercise | $33.63 | 147,101 | 4,947,163 | 436,743 | Jun 05, 2017, 06:03 PM |
| LEIDEN JEFFREY M | CEO & President | Jun 02, 2017 | Sale | $129.50 | 147,101 | 19,049,580 | 289,642 | Jun 05, 2017, 06:03 PM |
| Lee Yuchun | Director | Jun 02, 2017 | Sale | $128.44 | 1,323 | 169,926 | 4,847 | Jun 05, 2017, 05:56 PM |
| Bhatia Sangeeta N. | Director | Jun 02, 2017 | Sale | $128.44 | 1,176 | 151,045 | 3,953 | Jun 05, 2017, 05:07 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | May 15, 2017 | Sale | $114.37 | 181 | 20,701 | 106,011 | May 17, 2017, 04:25 PM |
| SMITH IAN F | EVP, CFO & COO | May 15, 2017 | Sale | $114.92 | 294 | 33,786 | 126,238 | May 17, 2017, 04:24 PM |
| Sachdev Amit | EVP, CRO | May 15, 2017 | Sale | $114.37 | 116 | 13,267 | 99,335 | May 17, 2017, 04:23 PM |
| Silva Paul M | SVP & Corp Controller | May 15, 2017 | Sale | $114.64 | 271 | 31,067 | 20,071 | May 17, 2017, 04:21 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | May 02, 2017 | Option Exercise | $91.05 | 8,979 | 817,538 | 131,490 | May 04, 2017, 08:51 AM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | May 02, 2017 | Sale | $121.05 | 8,979 | 1,086,908 | 122,511 | May 04, 2017, 08:51 AM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Apr 28, 2017 | Option Exercise | $63.14 | 7,500 | 473,550 | 113,511 | May 02, 2017, 05:18 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Apr 28, 2017 | Sale | $120.00 | 7,500 | 900,000 | 106,011 | May 02, 2017, 05:18 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Apr 28, 2017 | Option Exercise | $45.11 | 28,320 | 1,277,515 | 159,567 | May 02, 2017, 05:17 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Apr 28, 2017 | Sale | $119.50 | 28,320 | 3,384,240 | 131,247 | May 02, 2017, 05:17 PM |
| LEIDEN JEFFREY M | CEO & President | Apr 28, 2017 | Option Exercise | $31.51 | 140,034 | 4,412,253 | 446,679 | Apr 28, 2017, 04:44 PM |
| LEIDEN JEFFREY M | CEO & President | Apr 28, 2017 | Sale | $119.50 | 157,200 | 18,785,400 | 289,479 | Apr 28, 2017, 04:44 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Apr 05, 2017 | Option Exercise | $73.51 | 8,021 | 589,624 | 130,532 | Apr 07, 2017, 04:09 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Apr 05, 2017 | Sale | $114.00 | 8,021 | 914,394 | 122,511 | Apr 07, 2017, 04:09 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Apr 03, 2017 | Option Exercise | $73.51 | 2,291 | 168,411 | 124,802 | Apr 05, 2017, 04:55 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Apr 03, 2017 | Sale | $108.85 | 2,291 | 249,383 | 123,311 | Apr 05, 2017, 04:55 PM |
| Silva Paul M | SVP & Corp Controller | Mar 29, 2017 | Option Exercise | $45.11 | 1,688 | 76,146 | 21,759 | Mar 31, 2017, 04:09 PM |
| Silva Paul M | SVP & Corp Controller | Mar 29, 2017 | Sale | $106.30 | 1,688 | 179,434 | 20,071 | Mar 31, 2017, 04:09 PM |
| Sachdev Amit | EVP, CRO | Mar 29, 2017 | Option Exercise | $44.43 | 80,500 | 3,576,273 | 179,835 | Mar 31, 2017, 04:09 PM |
| Sachdev Amit | EVP, CRO | Mar 29, 2017 | Sale | $107.63 | 80,500 | 8,664,569 | 128,367 | Mar 31, 2017, 04:09 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Mar 29, 2017 | Option Exercise | $73.51 | 13,750 | 1,010,763 | 136,261 | Mar 31, 2017, 04:08 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Mar 29, 2017 | Sale | $106.65 | 13,750 | 1,466,438 | 122,511 | Mar 31, 2017, 04:08 PM |
| SMITH IAN F | EVP, CFO & COO | Feb 28, 2017 | Sale | $90.00 | 3,842 | 345,780 | 126,238 | Mar 02, 2017, 04:15 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 13, 2017 | Sale | $88.39 | 3,792 | 335,175 | 127,455 | Feb 15, 2017, 04:47 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 13, 2017 | Sale | $87.68 | 6,403 | 561,415 | 106,011 | Feb 15, 2017, 04:46 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 13, 2017 | Sale | $87.68 | 23,904 | 2,095,974 | 306,745 | Feb 15, 2017, 04:45 PM |
| Sachdev Amit | EVP, CRO | Feb 13, 2017 | Sale | $87.68 | 7,684 | 673,733 | 99,335 | Feb 15, 2017, 04:43 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Feb 13, 2017 | Sale | $87.67 | 5,122 | 449,046 | 122,511 | Feb 15, 2017, 04:42 PM |
| SMITH IAN F | EVP, CFO & COO | Feb 13, 2017 | Sale | $87.66 | 3,842 | 336,790 | 130,080 | Feb 15, 2017, 04:41 PM |
| ALTSHULER DAVID | EVP, Global Research and CSO | Feb 03, 2017 | Option Exercise | $0.01 | 4,794 | 48 | 94,210 | Feb 07, 2017, 04:56 PM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Feb 03, 2017 | Option Exercise | $0.01 | 5,753 | 58 | 119,111 | Feb 07, 2017, 04:50 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Feb 03, 2017 | Option Exercise | $0.01 | 4,794 | 48 | 115,497 | Feb 07, 2017, 04:49 PM |
| Sachdev Amit | EVP, CRO | Feb 03, 2017 | Option Exercise | $0.01 | 5,753 | 58 | 91,849 | Feb 07, 2017, 04:48 PM |
| SMITH IAN F | EVP, CFO & COO | Feb 03, 2017 | Option Exercise | $0.01 | 5,753 | 58 | 118,752 | Feb 07, 2017, 04:47 PM |
| LEIDEN JEFFREY M | CEO & President | Feb 03, 2017 | Option Exercise | $0.01 | 17,895 | 179 | 279,982 | Feb 07, 2017, 04:45 PM |
| Parini Michael | EVP, CLO & CAO | Feb 01, 2017 | Sale | $85.98 | 3,450 | 296,631 | 10,350 | Feb 03, 2017, 04:35 PM |
| Chodakewitz Jeffrey | EVP GMDA, CMO | Feb 01, 2017 | Sale | $85.74 | 1,900 | 162,897 | 112,203 | Feb 03, 2017, 04:34 PM |
| BOGER JOSHUA S | Director | Jan 11, 2017 | Option Exercise | $36.30 | 8,000 | 290,400 | 276,225 | Jan 13, 2017, 04:12 PM |
| BOGER JOSHUA S | Director | Jan 11, 2017 | Sale | $82.48 | 8,000 | 659,846 | 273,825 | Jan 13, 2017, 04:12 PM |
| BOGER JOSHUA S | Director | Jan 04, 2017 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Jan 06, 2017, 01:29 PM |
| BOGER JOSHUA S | Director | Jan 04, 2017 | Sale | $77.13 | 6,500 | 501,319 | 274,525 | Jan 06, 2017, 01:29 PM |
| BOGER JOSHUA S | Director | Dec 29, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Jan 03, 2017, 04:40 PM |
| BOGER JOSHUA S | Director | Dec 29, 2016 | Sale | $74.33 | 6,500 | 483,113 | 269,025 | Jan 03, 2017, 04:40 PM |
| BOGER JOSHUA S | Director | Dec 21, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Dec 22, 2016, 10:30 AM |
| BOGER JOSHUA S | Director | Dec 21, 2016 | Sale | $74.16 | 6,500 | 482,025 | 270,625 | Dec 22, 2016, 10:30 AM |
| BOGER JOSHUA S | Director | Dec 14, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Dec 16, 2016, 03:03 PM |
| BOGER JOSHUA S | Director | Dec 14, 2016 | Sale | $77.52 | 6,500 | 503,870 | 269,025 | Dec 16, 2016, 03:03 PM |
| BOGER JOSHUA S | Director | Dec 07, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Dec 09, 2016, 02:17 PM |
| BOGER JOSHUA S | Director | Dec 07, 2016 | Sale | $75.15 | 6,500 | 488,482 | 272,125 | Dec 09, 2016, 02:17 PM |
| BOGER JOSHUA S | Director | Nov 30, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Dec 02, 2016, 02:22 PM |
| BOGER JOSHUA S | Director | Nov 30, 2016 | Sale | $83.48 | 6,500 | 542,614 | 272,525 | Dec 02, 2016, 02:22 PM |
| BOGER JOSHUA S | Director | Nov 23, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Nov 28, 2016, 04:20 PM |
| BOGER JOSHUA S | Director | Nov 23, 2016 | Sale | $86.47 | 6,500 | 562,043 | 274,125 | Nov 28, 2016, 04:20 PM |
| BOGER JOSHUA S | Director | Nov 16, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Nov 17, 2016, 04:35 PM |
| BOGER JOSHUA S | Director | Nov 16, 2016 | Sale | $91.55 | 6,500 | 595,058 | 272,788 | Nov 17, 2016, 04:35 PM |
| Sachdev Amit | EVP, Policy, Access & Value | Nov 15, 2016 | Sale | $93.36 | 116 | 10,830 | 86,096 | Nov 17, 2016, 04:33 PM |
| Silva Paul M | SVP & Corp Controller | Nov 15, 2016 | Sale | $94.14 | 1 | 94 | 13,750 | Nov 17, 2016, 04:29 PM |
| BOGER JOSHUA S | Director | Nov 09, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Nov 14, 2016, 08:41 AM |
| BOGER JOSHUA S | Director | Nov 09, 2016 | Sale | $90.98 | 6,500 | 591,372 | 273,925 | Nov 14, 2016, 08:41 AM |
| Arbuckle Stuart A | EVPChief Commercial Officer | Nov 09, 2016 | Sale | $90.00 | 1,208 | 108,720 | 113,358 | Nov 14, 2016, 08:40 AM |
| Silva Paul M | SVP & Corp Controller | Nov 10, 2016 | Option Exercise | $45.11 | 1,687 | 76,101 | 18,812 | Nov 14, 2016, 08:39 AM |
| Silva Paul M | SVP & Corp Controller | Nov 09, 2016 | Option Exercise | $37.86 | 3,375 | 127,778 | 17,125 | Nov 14, 2016, 08:39 AM |
| Silva Paul M | SVP & Corp Controller | Nov 10, 2016 | Sale | $95.11 | 1,687 | 160,451 | 13,750 | Nov 14, 2016, 08:39 AM |
| Silva Paul M | SVP & Corp Controller | Nov 09, 2016 | Sale | $88.92 | 3,375 | 300,105 | 15,437 | Nov 14, 2016, 08:39 AM |
| BOGER JOSHUA S | Director | Nov 02, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Nov 04, 2016, 04:23 PM |
| BOGER JOSHUA S | Director | Nov 02, 2016 | Sale | $77.75 | 6,500 | 505,400 | 272,225 | Nov 04, 2016, 04:23 PM |
| BOGER JOSHUA S | Director | Oct 26, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Oct 28, 2016, 01:12 PM |
| BOGER JOSHUA S | Director | Oct 26, 2016 | Sale | $79.26 | 6,500 | 515,199 | 272,725 | Oct 28, 2016, 01:12 PM |
| BOGER JOSHUA S | Director | Oct 19, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Oct 21, 2016, 12:50 PM |
| BOGER JOSHUA S | Director | Oct 19, 2016 | Sale | $81.84 | 6,500 | 531,976 | 268,425 | Oct 21, 2016, 12:50 PM |
| BOGER JOSHUA S | Director | Oct 12, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Oct 14, 2016, 11:53 AM |
| BOGER JOSHUA S | Director | Oct 12, 2016 | Sale | $81.14 | 6,500 | 527,381 | 270,625 | Oct 14, 2016, 11:53 AM |
| BOGER JOSHUA S | Director | Oct 05, 2016 | Option Exercise | $36.30 | 6,500 | 235,950 | 274,725 | Oct 07, 2016, 11:56 AM |
| BOGER JOSHUA S | Director | Oct 05, 2016 | Sale | $87.44 | 6,500 | 568,379 | 273,925 | Oct 07, 2016, |