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| Stock | Company | % Portfolio | Shares Held | Market Value | Change in Shares | % Change | Quarter End Price | Source |
|---|---|---|---|---|---|---|---|---|
| SVA | SINOVAC BIOTECH LTD | 6.22% | 2,718,735 | $340,000,000 | No Change | $125.06 | 13F | |
| LLY | ELI LILLY & CO | 5.14% | 360,800 | $280,687,968 | -4,600 | -1.26% | $777.96 | 13F |
| EWTX | EDGEWISE THERAPEUTICS INC | 5.02% | 15,021,721 | $273,996,191 | 454,545 | 3.12% | $18.24 | 13F |
| BSX | BOSTON SCIENTIFIC CORP | 4.10% | 3,273,000 | $224,167,770 | -33,800 | -1.02% | $68.49 | 13F |
| ISRG | INTUITIVE SURGICAL INC | 3.60% | 493,100 | $196,791,279 | -5,900 | -1.18% | $399.09 | 13F |
| BIIB | BIOGEN INC | 3.56% | 900,900 | $194,261,067 | 73,300 | 8.86% | $215.63 | 13F |
| MRK | MERCK & CO INC | 3.18% | 1,316,000 | $173,646,200 | 261,000 | 24.74% | $131.95 | 13F |
| ELVN | Enliven Therapeutics, Inc. | 3.08% | 8,951,463 | $168,287,504 | -46,875 | -0.52% | 13D | |
| JANX | JANUX THERAPEUTICS INC | 2.95% | 4,275,553 | $160,974,570 | 957,626 | 28.86% | $37.65 | 13F |
| THC | TENET HEALTHCARE CORP | 2.26% | 1,173,300 | $123,325,563 | -51,100 | -4.17% | $105.11 | 13F |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 2.04% | 1,278,500 | $111,664,190 | -292,910 | -18.64% | $87.34 | 13F |
| ALPN | ALPINE IMMUNE SCIENCES INC | 1.95% | 2,680,496 | $106,254,861 | 145,251 | 5.73% | $39.64 | 13F |
| IRON | DISC MEDICINE INC | 1.94% | 1,702,237 | $105,981,276 | No Change | $62.26 | 13F | |
| SYK | STRYKER CORPORATION | 1.76% | 269,000 | $96,267,030 | No Change | $357.87 | 13F | |
| SPRY | ARS PHARMACEUTICALS INC | 1.73% | 9,240,887 | $94,441,865 | No Change | $10.22 | 13F | |
| SRPT | SAREPTA THERAPEUTICS INC | 1.65% | 697,500 | $90,298,350 | No Change | $129.46 | 13F | |
| ELV | ELEVANCE HEALTH INC | 1.60% | 168,100 | $87,166,574 | 26,600 | 18.8% | $518.54 | 13F |
| IONS | IONIS PHARMACEUTICALS INC | 1.60% | 2,013,033 | $87,264,981 | -51,764 | -2.51% | $43.35 | 13F |
| XTNT | XTANT MED HLDGS INC | 1.57% | 73,114,592 | $85,544,073 | No Change | $1.17 | 13F | |
| EVH | EVOLENT HEALTH INC | 1.56% | 2,605,615 | $85,438,116 | -140,917 | -5.13% | $32.79 | 13F |
| KROS | KEROS THERAPEUTICS INC | 1.54% | 1,268,734 | $83,990,191 | No Change | $66.2 | 13F | |
| SWTX | SPRINGWORKS THERAPEUTICS INC | 1.54% | 1,707,331 | $84,034,832 | -1,512,028 | -46.97% | $49.22 | 13F |
| NTRA | NATERA INC | 1.51% | 899,431 | $82,261,959 | -55,050 | -5.77% | $91.46 | 13F |
| APLS | APELLIS PHARMACEUTICALS INC | 1.40% | 1,297,800 | $76,284,684 | 375,600 | 40.73% | $58.78 | 13F |
| TMO | THERMO FISHER SCIENTIFIC INC | 1.40% | 132,000 | $76,719,720 | -11,800 | -8.21% | $581.21 | 13F |
| PCVX | VAXCYTE INC | 1.33% | 1,066,131 | $72,827,409 | -86,960 | -7.54% | $68.31 | 13F |
| CRNX | CRINETICS PHARMACEUTICALS IN | 1.19% | 1,385,000 | $64,831,850 | -282,360 | -16.93% | $46.81 | 13F |
| SRRK | SCHOLAR ROCK HLDG CORP | 1.16% | 3,574,632 | $63,485,464 | -670,368 | -15.79% | $17.76 | 13F |
| ARGX | ARGENX SE | 1.09% | 151,600 | $59,687,952 | 67,000 | 79.2% | $393.72 | 13F |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1.07% | 423,100 | $58,353,952 | -96,179 | -18.52% | $137.92 | 13F |
| ICLR | ICON PLC | 1.07% | 174,100 | $58,488,895 | 41,900 | 31.69% | $335.95 | 13F |
| THRD | THIRD HARMONIC BIO INC | 1.00% | 5,779,071 | $54,554,430 | No Change | $9.44 | 13F | |
| VRNA | VERONA PHARMA PLC | 1.00% | 3,398,067 | $54,674,898 | -379,711 | -10.05% | $16.09 | 13F |
| AVBP | ARRIVENT BIOPHARMA INC | 0.99% | 3,027,328 | $54,068,078 | 3,027,328 | New | $17.86 | 13F |
| PRLD | PRELUDE THERAPEUTICS INC | 0.95% | 10,909,256 | $51,709,873 | No Change | $4.74 | 13F | |
| SIBN | SI-BONE INC | 0.95% | 3,174,521 | $51,966,909 | 881,990 | 38.47% | $16.37 | 13F |
| VRTX | VERTEX PHARMACEUTICALS INC | 0.94% | 122,700 | $51,289,827 | -52,500 | -29.97% | $418.01 | 13F |
| TERN | TERNS PHARMACEUTICALS INC | 0.91% | 7,619,135 | $49,981,526 | No Change | $6.56 | 13F | |
| CYTK | CYTOKINETICS INC | 0.88% | 682,700 | $47,864,097 | 682,700 | New | $70.11 | 13F |
| APGE | APOGEE THERAPEUTICS INC | 0.87% | 718,901 | $47,770,971 | -559,000 | -43.74% | $66.45 | 13F |
| NPCE | NeuroPace Inc | 0.87% | 3,406,335 | $47,790,880 | -597,632 | -14.93% | Form 4 | |
| CMPX | COMPASS THERAPEUTICS INC | 0.81% | 22,362,850 | $44,278,443 | No Change | $1.98 | 13F | |
| GERN | GERON CORP | 0.78% | 12,893,611 | $42,548,916 | 12,408,611 | 2558.48% | $3.3 | 13F |
| SNDX | SYNDAX PHARMACEUTICALS INC | 0.76% | 1,749,000 | $41,626,200 | No Change | $23.8 | 13F | |
| QTTB | Q32 BIO INC | 0.70% | 2,252,987 | $38,390,898 | 2,252,987 | New | $17.04 | 13F |
| ESPR | ESPERION THERAPEUTICS INC NE | 0.67% | 13,708,731 | $36,739,399 | 13,708,731 | New | $2.68 | 13F |
| IKNA | IKENA ONCOLOGY INC | 0.66% | 12,048,773 | $35,967,476 | No Change | $2.99 | 13F | |
| UNH | UNITEDHEALTH GROUP INC | 0.63% | 70,000 | $34,629,000 | No Change | $494.7 | 13F | |
| RYTM | RHYTHM PHARMACEUTICALS INC | 0.56% | 704,842 | $30,540,804 | 168,200 | 31.34% | $43.33 | 13F |
| ALXO | ALX ONCOLOGY HLDGS INC | 0.55% | 2,717,970 | $30,305,366 | -377,030 | -12.18% | $11.15 | 13F |
| VERA | VERA THERAPEUTICS INC | 0.53% | 675,872 | $29,143,601 | -842,243 | -55.48% | $43.12 | 13F |
| HRTX | HERON THERAPEUTICS INC | 0.51% | 10,111,550 | $28,008,994 | 4,182,959 | 70.56% | $2.77 | 13F |
| PRAX | PRAXIS PRECISION MEDICINES I | 0.51% | 460,512 | $28,100,442 | 460,512 | New | $61.02 | 13F |
| SCPH | SCPHARMACEUTICALS INC | 0.51% | 5,559,528 | $27,908,831 | No Change | $5.02 | 13F | |
| SLRN | ACELYRIN INC | 0.49% | 4,001,711 | $27,011,549 | No Change | $6.75 | 13F | |
| ACET | ADICET BIO INC | 0.49% | 11,447,140 | $26,900,779 | 3,125,000 | 37.55% | $2.35 | 13F |
| MLYS | MINERALYS THERAPEUTICS INC | 0.48% | 2,021,424 | $26,096,584 | 2,021,424 | New | $12.91 | 13F |
| RNA | AVIDITY BIOSCIENCES INC | 0.46% | 994,100 | $25,369,432 | 994,100 | New | $25.52 | 13F |
| XENE | XENON PHARMACEUTICALS INC | 0.43% | 550,000 | $23,677,500 | No Change | $43.05 | 13F | |
| REGN | REGENERON PHARMACEUTICALS | 0.40% | 22,800 | $21,944,772 | 9,300 | 68.89% | $962.49 | 13F |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 0.39% | 739,651 | $21,154,019 | 420,000 | 131.39% | $28.6 | 13F |
| KNTE | KINNATE BIOPHARMA INC | 0.39% | 8,009,729 | $21,305,879 | No Change | $2.66 | 13F | |
| NMRA | NEUMORA THERAPEUTICS INC. | 0.38% | 1,500,000 | $20,625,000 | No Change | $13.75 | 13F | |
| DYN | DYNE THERAPEUTICS INC | 0.37% | 708,400 | $20,111,476 | 708,400 | New | $28.39 | 13F |
| DXCM | DEXCOM INC | 0.36% | 140,300 | $19,459,610 | 67,100 | 91.67% | $138.7 | 13F |
| MORF | MORPHIC HLDG INC | 0.36% | 558,500 | $19,659,200 | 285,100 | 104.28% | $35.2 | 13F |
| ABCL | ABCELLERA BIOLOGICS INC | 0.35% | 4,180,768 | $18,938,879 | No Change | $4.53 | 13F | |
| IMTX | IMMATICS N.V | 0.34% | 1,769,708 | $18,599,631 | 226,301 | 14.66% | $10.51 | 13F |
| AMGN | AMGEN INC | 0.33% | 63,400 | $18,025,888 | -63,900 | -50.2% | $284.32 | 13F |
| VSTM | VERASTEM INC | 0.33% | 1,529,115 | $18,043,557 | No Change | $11.8 | 13F | |
| AVTE | AEROVATE THERAPEUTICS INC | 0.31% | 565,374 | $16,718,109 | -191,556 | -25.31% | $29.57 | 13F |
| RPTX | REPARE THERAPEUTICS INC | 0.29% | 3,322,488 | $15,648,918 | No Change | $4.71 | 13F | |
| TELA | TELA BIO INC | 0.29% | 2,835,542 | $16,077,523 | No Change | $5.67 | 13F | |
| CRVS | Corvus Pharmaceuticals, Inc. | 0.24% | 6,943,654 | $13,262,379 | No Change | 13D | ||
| TYRA | TYRA BIOSCIENCES INC | 0.23% | 768,638 | $12,605,663 | 768,638 | New | $16.4 | 13F |
| IVVD | INVIVYD INC | 0.22% | 2,690,300 | $11,944,932 | -1,437,265 | -34.82% | $4.44 | 13F |
| PMVP | PMV PHARMACEUTICALS INC | 0.20% | 6,475,291 | $11,007,995 | No Change | $1.7 | 13F | |
| PASG | Passage BIO, Inc. | 0.19% | 8,034,000 | $10,604,880 | -2,090,576 | -20.65% | 13D | |
| VTYX | VENTYX BIOSCIENCES INC | 0.19% | 1,870,456 | $10,287,508 | 1,870,456 | New | $5.5 | 13F |
| EXAS | EXACT SCIENCES CORP | 0.18% | 140,400 | $9,696,024 | 140,400 | New | $69.06 | 13F |
| FATE | FATE THERAPEUTICS INC | 0.18% | 1,355,352 | $9,948,284 | 827,272 | 156.66% | $7.34 | 13F |
| XFOR | X4 PHARMACEUTICALS INC | 0.18% | 7,133,515 | $9,915,586 | No Change | $1.39 | 13F | |
| APLS | APELLIS PHARMACEUTICALS INC (Call) | 0.16% | 150,000 | $8,817,000 | 150,000 | New | $58.78 | 13F |
| CGEM | CULLINAN ONCOLOGY INC | 0.16% | 517,606 | $8,820,006 | -27,242 | -5% | $17.04 | 13F |
| LXRX | LEXICON PHARMACEUTICALS INC | 0.16% | 3,542,000 | $8,500,800 | 3,542,000 | New | $2.4 | 13F |
| NKTX | NKARTA INC | 0.16% | 800,000 | $8,648,000 | 800,000 | New | $10.81 | 13F |
| TXG | 10X GENOMICS INC | 0.15% | 225,200 | $8,451,756 | 185,400 | 465.83% | $37.53 | 13F |
| TSBX | TURNSTONE BIOLOGICS CORP | 0.15% | 3,099,265 | $8,120,074 | No Change | $2.62 | 13F | |
| CTMX | CYTOMX THERAPEUTICS INC | 0.14% | 3,544,578 | $7,727,180 | 3,544,578 | New | $2.18 | 13F |
| CATX | PERSPECTIVE THERAPEUTICS INC | 0.14% | 6,505,800 | $7,741,902 | 6,505,800 | New | $1.19 | 13F |
| FOLD | AMICUS THERAPEUTICS INC | 0.12% | 570,300 | $6,718,134 | -235,700 | -29.24% | $11.78 | 13F |
| KRYS | KRYSTAL BIOTECH INC | 0.12% | 37,166 | $6,612,946 | -66,534 | -64.16% | $177.93 | 13F |
| VIR | VIR BIOTECHNOLOGY INC | 0.12% | 640,000 | $6,483,200 | 539,000 | 533.66% | $10.13 | 13F |
| APLM | APOLLOMICS INC | 0.12% | 8,565,456 | $6,424,092 | No Change | $0.75 | 13F | |
| ELEV | ELEVATION ONCOLOGY INC | 0.09% | 941,275 | $4,828,741 | -558,725 | -37.25% | $5.13 | 13F |
| IKNA | IKENA ONCOLOGY INC | 0.09% | 3,539,358 | $5,025,888 | No Change | $1.42 | 13F | |
| NSPR | INSPIREMD INC | 0.09% | 2,133,405 | $5,056,383 | No Change | $2.37 | 13F | |
| PGNY | PROGYNY INC | 0.08% | 113,300 | $4,322,395 | 113,300 | New | $38.15 | 13F |
| MIST | MILESTONE PHARMACEUTICALS IN | 0.07% | 2,000,000 | $3,580,000 | 2,000,000 | New | $1.79 | 13F |
| ORIC | ORIC PHARMACEUTICALS INC | 0.07% | 287,100 | $3,947,625 | -235,868 | -45.1% | $13.75 | 13F |
| SIBN | SI-BONE INC (Call) | 0.07% | 250,000 | $4,092,500 | 250,000 | New | $16.37 | 13F |
| NXTC | NEXTCURE INC | 0.05% | 1,141,200 | $2,544,876 | -1,569,813 | -57.91% | $2.23 | 13F |
| PHGE | BIOMX INC | 0.04% | 4,517,589 | $2,032,915 | No Change | $0.45 | 13F | |
| BOLT | BOLT BIOTHERAPEUTICS INC | 0.04% | 1,541,000 | $2,157,400 | No Change | $1.4 | 13F | |
| CMMB | CHEMOMAB THERAPEUTICS LTD | 0.03% | 2,241,274 | $1,745,952 | No Change | $0.78 | 13F | |
| DVAX | DYNAVAX TECHNOLOGIES CORP | 0.03% | 113,500 | $1,408,535 | 113,500 | New | $12.41 | 13F |
| KZR | KEZAR LIFE SCIENCES INC | 0.03% | 1,927,000 | $1,737,383 | No Change | $0.9 | 13F | |
| VIGL | VIGIL NEUROSCIENCE INC | 0.03% | 448,891 | $1,530,718 | No Change | $3.41 | 13F | |
| CALC | CALCIMEDICA INC | 0.02% | 297,380 | $1,237,101 | No Change | $4.16 | 13F | |
| YS | YS BIOPHARMA CO LTD | 0.02% | 1,534,430 | $1,104,636 | -1,701,881 | -52.59% | $0.72 | 13F |
| AFIB | ACUTUS MED INC | 0.00911% | 2,648,386 | $497,897 | No Change | $0.19 | 13F | |
| LYEL | LYELL IMMUNOPHARMA INC | 0.00814% | 199,500 | $444,885 | 199,500 | New | $2.23 | 13F |
| OMIC | SINGULAR GENOMICS SYSTEMS IN | 0.00509% | 540,697 | $278,026 | No Change | $0.51 | 13F | |
| XERS | XERIS BIOPHARMA HOLDINGS INC | 0.00325% | 80,420 | $177,728 | 80,420 | New | $2.21 | 13F |
| AGIO | AGIOS PHARMACEUTICALS INC | -45,000 | Exited | 13F | ||||
| ALNY | ALNYLAM PHARMACEUTICALS INC | -79,400 | Exited | 13F | ||||
| RCUS | ARCUS BIOSCIENCES INC | -117,000 | Exited | 13F | ||||
| CLDX | CELLDEX THERAPEUTICS INC NEW | -58,800 | Exited | 13F | ||||
| FUSN | FUSION PHARMACEUTICALS INC | -3,122,770 | Exited | 13F | ||||
| GILD | GILEAD SCIENCES INC | -100,000 | Exited | 13F | ||||
| GRCL | GRACELL BIOTECHNOLOGIES INC | -9,308,726 | Exited | 13F | ||||
| HUM | HUMANA INC | -109,900 | Exited | 13F | ||||
| ILMN | ILLUMINA INC | -30,300 | Exited | 13F | ||||
| IOVA | IOVANCE BIOTHERAPEUTICS INC | -4,707,458 | Exited | 13F | ||||
| AMAM | AMBRX BIOPHARMA INC | -296,000 | Exited | 13F | ||||
| PFE | PFIZER INC (Call) | -500,000 | Exited | 13F | ||||
| RAPT | RAPT THERAPEUTICS INC | -281,413 | Exited | 13F | ||||
| RYZB | RAYZEBIO INC | -2,365,213 | Exited | 13F | ||||
| RCM | R1 RCM INC | -4,803,200 | Exited | 13F | ||||
| THRX | THESEUS PHARMACEUTICALS INC | -17,713,600 | Exited | 13F | ||||
| UTHR | UNITED THERAPEUTICS CORP DEL | -386,100 | Exited | 13F | ||||
| QURE | UNIQURE NV | -1,347,900 | Exited | 13F |