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| Stock | Company | % Portfolio | Shares Held | Market Value | Change in Shares | % Change | Quarter End Price | Source |
|---|---|---|---|---|---|---|---|---|
| ELVN | Enliven Therapeutics, Inc. | 3.33% | 8,951,463 | $168,287,504 | -46,875 | -0.52% | 13D | |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 2.87% | 1,571,410 | $151,515,352 | -43,800 | -2.71% | $96.42 | 13F |
| RYZB | RAYZEBIO INC | 2.79% | 2,365,213 | $147,045,292 | -257,696 | -9.82% | $62.17 | 13F |
| SWTX | SPRINGWORKS THERAPEUTICS INC | 2.23% | 3,219,359 | $117,506,604 | -749,229 | -18.88% | $36.5 | 13F |
| IONS | IONIS PHARMACEUTICALS INC | 1.98% | 2,064,797 | $104,458,080 | -104,703 | -4.83% | $50.59 | 13F |
| IRON | DISC MEDICINE INC | 1.86% | 1,702,237 | $98,321,209 | -567,400 | -25% | $57.76 | 13F |
| EVH | EVOLENT HEALTH INC | 1.72% | 2,746,532 | $90,717,952 | -149,100 | -5.15% | $33.03 | 13F |
| UTHR | UNITED THERAPEUTICS CORP DEL | 1.61% | 386,100 | $84,899,529 | -15,800 | -3.93% | $219.89 | 13F |
| CRNX | CRINETICS PHARMACEUTICALS IN | 1.12% | 1,667,360 | $59,324,669 | -1,228,714 | -42.43% | $35.58 | 13F |
| APLS | APELLIS PHARMACEUTICALS INC | 1.05% | 922,200 | $55,202,892 | -338,300 | -26.84% | $59.86 | 13F |
| KROS | KEROS THERAPEUTICS INC | 0.96% | 1,268,734 | $50,444,864 | -246,000 | -16.24% | $39.76 | 13F |
| HUM | HUMANA INC | 0.95% | 109,900 | $50,313,319 | -232,600 | -67.91% | $457.81 | 13F |
| NPCE | NeuroPace Inc | 0.94% | 3,501,975 | $49,237,769 | -501,992 | -12.54% | Form 4 | |
| ALPN | ALPINE IMMUNE SCIENCES INC | 0.92% | 2,535,245 | $48,321,770 | -1,546,347 | -37.89% | $19.06 | 13F |
| CMPX | Compass Therapeutics, Inc. | 0.83% | 18,791,422 | $42,092,785 | -3,571,428 | -15.97% | 13D | |
| APGE | APOGEE THERAPEUTICS INC | 0.68% | 1,277,901 | $35,704,554 | -150,000 | -10.5% | $27.94 | 13F |
| SLRN | ACELYRIN INC | 0.57% | 4,001,711 | $29,852,764 | -1,324,591 | -24.87% | $7.46 | 13F |
| XENE | XENON PHARMACEUTICALS INC | 0.48% | 550,000 | $25,333,000 | -408,793 | -42.64% | $46.06 | 13F |
| RYTM | RHYTHM PHARMACEUTICALS INC | 0.47% | 536,642 | $24,669,433 | -47,000 | -8.05% | $45.97 | 13F |
| KNTE | Kinnate Biopharma Inc. | 0.38% | 7,559,729 | $19,277,309 | -450,000 | -5.62% | 13D | |
| PMVP | PMV PHARMACEUTICALS INC | 0.38% | 6,475,291 | $20,073,402 | -87,786 | -1.34% | $3.1 | 13F |
| IVVD | INVIVYD INC | 0.31% | 4,127,565 | $16,262,606 | -1,142,835 | -21.68% | $3.94 | 13F |
| PASG | Passage BIO, Inc. | 0.21% | 8,034,000 | $10,604,880 | -2,090,576 | -20.65% | 13D | |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 0.19% | 319,651 | $9,781,321 | -114,000 | -26.29% | $30.6 | 13F |
| QURE | UNIQURE NV | 0.17% | 1,347,900 | $9,125,283 | -716,555 | -34.71% | $6.77 | 13F |
| APLM | APOLLOMICS INC | 0.16% | 8,565,456 | $8,265,665 | -9,428,179 | -52.4% | $0.96 | 13F |
| RAPT | RAPT THERAPEUTICS INC | 0.13% | 281,413 | $6,993,113 | -963,532 | -77.4% | $24.85 | 13F |
| ORIC | ORIC PHARMACEUTICALS INC | 0.09% | 522,968 | $4,811,306 | -370,700 | -41.48% | $9.2 | 13F |
| NXTC | NextCure, Inc. | 0.04% | 1,268,013 | $2,142,942 | -1,443,000 | -53.23% | 13D | |
| KZR | KEZAR LIFE SCIENCES INC | 0.03% | 1,927,000 | $1,825,640 | -3,536,000 | -64.73% | $0.95 | 13F |
| YS | YS BIOPHARMA CO LTD | 0.03% | 3,236,311 | $1,653,755 | -1,305,111 | -28.74% | $0.51 | 13F |
| PHGE | BIOMX INC | 0.02% | 4,517,589 | $1,264,925 | -35,900 | -0.79% | $0.28 | 13F |