Blueprint Medicines Corporation (BPMC) NASDAQ
$87.03 2.93 (3.48%)
Market Cap: $5.51B
As of 09/13/24 12:01 PM EDT. Market open.
Blueprint Medicines Corporation (BPMC)
NASDAQ
$87.03
2.93 (3.48%)
Market Cap: $5.51B
As of 09/13/24 12:01 PM EDT. Market open.
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Blueprint Medicines Corporation, a precision therapy company, develops medicines for genomically defined cancers and blood disorders in the United States and internationally. The company is developing AYVAKIT for the treatment of systemic mastocytosis (SM) and gastrointestinal stromal tumors; BLU-263, an orally available, potent, and KIT inhibitor for the treatment of non-advanced SM and other ... read more
COMPANY PROFILE
Sector
Healthcare
Industry
Biotechnology
CEO
Ms. Kathryn Haviland
Full Time Employees
638
CEO Compensation (Base)
$782,250
CEO Compensation (Total)
$6.43M
Sector
Healthcare
Industry
Biotechnology
CEO
Ms. Kathryn Haviland
Full Time Employees
638
CEO Compensation (Base)
$782,250
CEO Compensation (Total)
$6.43M
Address
45 Sidney Street, MA, Cambridge, 02139.
PRICE CHART FOR BLUEPRINT MEDICINES CORPORATION
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To:
NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
$85.09
Previous Close
$84.10
Days Range
$84.38 - $87.47
52 week range
$43.89 - $121.90
Volume
169,205
Avg. Volume (30 days)
683,835
Market Cap
$5.51B
Dividend Yield
-
P/E
(25.52)
Shares Outstanding
63,345,500
Open
$85.09
Previous Close
$84.10
Days Range
$84.38 - $87.47
52 week range
$43.89 - $121.90
Volume
169,205
Avg. Volume (30 days)
683,835
Market Cap
$5.51B
Dividend Yield
-
P/E
(25.52)
Shares Outstanding
63,345,500
FINANCIAL STATEMENTS FOR BLUEPRINT MEDICINES CORPORATION
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INSIDER TRANSACTIONS FOR BLUEPRINT MEDICINES CORPORATION
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| Albers Jeffrey W. | Director | Sep 09, 2024 | Option Exercise | $36.05 | 10,000 | 360,500 | 177,259 | Sep 11, 2024, 04:06 PM |
| Albers Jeffrey W. | Director | Sep 09, 2024 | Sale | $85.57 | 19,702 | 1,685,891 | 165,291 | Sep 11, 2024, 04:06 PM |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | Aug 15, 2024 | Sale | $95.23 | 4,409 | 419,869 | 67,208 | Aug 19, 2024, 04:00 PM |
| Lee Philina | CHIEF COMMERCIAL OFFICER | Aug 05, 2024 | Option Exercise | $67.50 | 41,913 | 2,828,921 | 76,642 | Aug 07, 2024, 05:06 PM |
| Lee Philina | CHIEF COMMERCIAL OFFICER | Aug 05, 2024 | Sale | $93.19 | 41,913 | 3,905,873 | 34,729 | Aug 07, 2024, 05:06 PM |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | Jul 03, 2024 | Option Exercise | $54.13 | 8,817 | 477,264 | 52,580 | Jul 08, 2024, 04:05 PM |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | Jul 05, 2024 | Option Exercise | $54.13 | 3,850 | 208,401 | 47,613 | Jul 08, 2024, 04:05 PM |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | Jul 03, 2024 | Sale | $111.29 | 8,817 | 981,244 | 43,763 | Jul 08, 2024, 04:05 PM |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | Jul 05, 2024 | Sale | $111.20 | 3,850 | 428,120 | 43,763 | Jul 08, 2024, 04:05 PM |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | Jun 21, 2024 | Option Exercise | $34.48 | 60,482 | 2,085,501 | 117,797 | Jun 25, 2024, 04:00 PM |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | Jun 21, 2024 | Sale | $104.19 | 74,034 | 7,713,537 | 116,230 | Jun 25, 2024, 04:00 PM |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | Jun 04, 2024 | Sale | $104.91 | 2,424 | 254,302 | 29,514 | Jun 06, 2024, 04:00 PM |
| Carter Percy H. | CHIEF SCIENTIFIC OFFICER | Jun 03, 2024 | Sale | $106.43 | 2,436 | 259,263 | 45,895 | Jun 05, 2024, 04:00 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | May 15, 2024 | Option Exercise | $37.69 | 5,856 | 220,736 | 20,769 | May 17, 2024, 04:05 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | May 15, 2024 | Sale | $106.96 | 5,856 | 626,379 | 17,187 | May 17, 2024, 04:05 PM |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | May 08, 2024 | Option Exercise | $2.32 | 28,181 | 65,297 | 75,467 | May 10, 2024, 04:05 PM |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | May 02, 2024 | Option Exercise | $36.05 | 10,000 | 360,500 | 57,286 | May 06, 2024, 05:26 PM |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | May 02, 2024 | Sale | $105.00 | 10,000 | 1,050,000 | 47,286 | May 06, 2024, 05:26 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | May 02, 2024 | Option Exercise | $54.13 | 1,834 | 99,274 | 16,747 | May 06, 2024, 05:19 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | May 02, 2024 | Sale | $103.88 | 1,834 | 190,516 | 14,913 | May 06, 2024, 05:19 PM |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | Mar 28, 2024 | Option Exercise | $36.05 | 5,000 | 180,250 | 52,286 | Apr 01, 2024, 04:34 PM |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | Mar 28, 2024 | Sale | $95.00 | 5,000 | 475,000 | 47,286 | Apr 01, 2024, 04:34 PM |
| Albers Jeffrey W. | Director | Mar 07, 2024 | Sale | $90.69 | 11,033 | 1,000,583 | 165,017 | Mar 26, 2024, 09:11 PM |
| Albers Jeffrey W. | Director | Mar 20, 2024 | Option Exercise | $7.11 | 25,073 | 178,287 | 201,123 | Mar 22, 2024, 05:50 PM |
| Albers Jeffrey W. | Director | Mar 20, 2024 | Sale | $87.28 | 25,073 | 2,188,265 | 198,393 | Mar 22, 2024, 05:50 PM |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | Mar 15, 2024 | Option Exercise | $36.05 | 5,000 | 180,250 | 61,020 | Mar 19, 2024, 05:11 PM |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | Mar 15, 2024 | Sale | $87.78 | 13,734 | 1,205,606 | 58,345 | Mar 19, 2024, 05:11 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Mar 15, 2024 | Option Exercise | $15.01 | 1,600 | 24,016 | 18,662 | Mar 19, 2024, 04:48 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Mar 15, 2024 | Sale | $87.76 | 4,549 | 399,213 | 17,862 | Mar 19, 2024, 04:48 PM |
| Lee Philina | CHIEF COMMERCIAL OFFICER | Mar 13, 2024 | Option Exercise | $13.15 | 1,747 | 22,975 | 42,752 | Mar 15, 2024, 04:47 PM |
| Lee Philina | CHIEF COMMERCIAL OFFICER | Mar 13, 2024 | Sale | $90.40 | 8,023 | 725,277 | 36,529 | Mar 15, 2024, 04:47 PM |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | Mar 07, 2024 | Sale | $90.69 | 3,097 | 280,867 | 46,281 | Mar 11, 2024, 06:29 PM |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | Mar 07, 2024 | Sale | $90.69 | 5,093 | 461,884 | 57,585 | Mar 11, 2024, 06:28 PM |
| Haviland Kate | CHIEF EXECUTIVE OFFICER | Mar 07, 2024 | Sale | $90.69 | 12,464 | 1,130,360 | 153,177 | Mar 11, 2024, 06:27 PM |
| Lee Philina | CHIEF COMMERCIAL OFFICER | Mar 07, 2024 | Sale | $90.69 | 2,934 | 266,084 | 41,005 | Mar 11, 2024, 06:26 PM |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | Mar 07, 2024 | Sale | $90.69 | 2,521 | 228,629 | 33,853 | Mar 11, 2024, 06:24 PM |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | Mar 07, 2024 | Sale | $90.69 | 5,003 | 453,722 | 56,020 | Mar 11, 2024, 06:23 PM |
| Rossi Christina | CHIEF OPERATING OFFICER | Mar 07, 2024 | Sale | $90.69 | 6,070 | 550,488 | 64,306 | Mar 11, 2024, 06:21 PM |
| Namouni Fouad | PRESIDENT, R & D | Mar 07, 2024 | Sale | $90.69 | 4,377 | 396,950 | 72,703 | Mar 11, 2024, 06:20 PM |
| Carter Percy H. | CHIEF SCIENTIFIC OFFICER | Mar 07, 2024 | Sale | $90.69 | 2,286 | 207,317 | 48,331 | Mar 11, 2024, 06:19 PM |
| McCain Tracey L | EVP AND CHIEF LEGAL OFFICER | Mar 07, 2024 | Sale | $90.69 | 5,194 | 471,044 | 60,498 | Mar 11, 2024, 06:18 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Mar 07, 2024 | Sale | $90.69 | 1,462 | 132,589 | 17,862 | Mar 11, 2024, 06:15 PM |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | Mar 04, 2024 | Sale | $93.65 | 621 | 58,157 | 36,374 | Mar 06, 2024, 10:41 AM |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | Feb 28, 2024 | Option Exercise | $54.13 | 5,000 | 270,650 | 29,495 | Mar 01, 2024, 03:06 PM |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | Feb 28, 2024 | Sale | $100.00 | 5,000 | 500,000 | 24,495 | Mar 01, 2024, 03:06 PM |
| Lee Philina | CHIEF COMMERCIAL OFFICER | Dec 13, 2023 | Option Exercise | $1.87 | 261 | 488 | 31,439 | Feb 14, 2024, 06:54 PM |
| Albers Jeffrey W. | Director | Jan 25, 2024 | Option Exercise | $7.13 | 25,000 | 178,150 | 201,050 | Jan 29, 2024, 06:13 PM |
| Albers Jeffrey W. | Director | Jan 25, 2024 | Sale | $81.91 | 25,000 | 2,047,800 | 194,964 | Jan 29, 2024, 06:13 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Dec 22, 2023 | Option Exercise | $8.80 | 714 | 6,283 | 15,038 | Dec 26, 2023, 04:24 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Dec 22, 2023 | Sale | $90.00 | 714 | 64,260 | 14,324 | Dec 26, 2023, 04:24 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Dec 15, 2023 | Option Exercise | $1.87 | 3,654 | 6,833 | 16,411 | Dec 19, 2023, 04:05 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Dec 15, 2023 | Sale | $84.35 | 3,914 | 330,146 | 14,584 | Dec 19, 2023, 04:05 PM |
| Albers Jeffrey W. | Director | Dec 11, 2023 | Option Exercise | $36.05 | 5,000 | 180,250 | 181,050 | Dec 13, 2023, 03:56 PM |
| Albers Jeffrey W. | Director | Dec 11, 2023 | Sale | $79.07 | 5,000 | 395,350 | 176,050 | Dec 13, 2023, 03:56 PM |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | Dec 07, 2023 | Option Exercise | $54.13 | 5,000 | 270,650 | 29,495 | Dec 11, 2023, 05:11 PM |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | Dec 07, 2023 | Sale | $75.00 | 5,000 | 375,000 | 24,495 | Dec 11, 2023, 05:11 PM |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | Dec 04, 2023 | Sale | $71.43 | 600 | 42,858 | 24,495 | Dec 06, 2023, 08:45 PM |
| Albers Jeffrey W. | Director | Nov 30, 2023 | Option Exercise | $36.05 | 5,000 | 180,250 | 181,050 | Dec 04, 2023, 04:02 PM |
| Albers Jeffrey W. | Director | Nov 30, 2023 | Sale | $70.55 | 5,000 | 352,750 | 176,050 | Dec 04, 2023, 04:02 PM |
| Albers Jeffrey W. | Director | Nov 24, 2023 | Option Exercise | $1.87 | 15,000 | 28,050 | 191,050 | Nov 28, 2023, 04:05 PM |
| Albers Jeffrey W. | Director | Nov 24, 2023 | Sale | $67.51 | 15,000 | 1,012,690 | 183,086 | Nov 28, 2023, 04:05 PM |
| Albers Jeffrey W. | Director | Nov 01, 2023 | Option Exercise | $36.05 | 3,881 | 139,910 | 179,931 | Nov 03, 2023, 05:07 PM |
| Albers Jeffrey W. | Director | Nov 03, 2023 | Option Exercise | $36.05 | 1,485 | 53,534 | 177,535 | Nov 03, 2023, 05:07 PM |
| Albers Jeffrey W. | Director | Nov 02, 2023 | Option Exercise | $36.05 | 4,634 | 167,056 | 180,684 | Nov 03, 2023, 05:07 PM |
| Albers Jeffrey W. | Director | Nov 03, 2023 | Sale | $60.13 | 1,485 | 89,293 | 176,050 | Nov 03, 2023, 05:07 PM |
| Albers Jeffrey W. | Director | Nov 02, 2023 | Sale | $60.37 | 4,634 | 279,749 | 176,109 | Nov 03, 2023, 05:07 PM |
| Albers Jeffrey W. | Director | Nov 01, 2023 | Sale | $60.02 | 3,881 | 232,938 | 176,050 | Nov 03, 2023, 05:07 PM |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | Oct 26, 2023 | Sale | $56.40 | 600 | 33,840 | 25,095 | Oct 30, 2023, 02:01 PM |
| Namouni Fouad | PRESIDENT, R & D | Oct 04, 2023 | Sale | $48.06 | 3,769 | 181,138 | 62,080 | Oct 05, 2023, 10:47 AM |
| Albers Jeffrey W. | Director | Sep 27, 2023 | Option Exercise | $1.87 | 18,102 | 33,851 | 194,152 | Sep 29, 2023, 02:36 PM |
| Albers Jeffrey W. | Director | Sep 28, 2023 | Option Exercise | $1.87 | 6,898 | 12,899 | 182,948 | Sep 29, 2023, 02:36 PM |
| Albers Jeffrey W. | Director | Sep 28, 2023 | Sale | $50.17 | 6,898 | 346,073 | 176,050 | Sep 29, 2023, 02:36 PM |
| Albers Jeffrey W. | Director | Sep 27, 2023 | Sale | $49.61 | 18,102 | 897,957 | 188,552 | Sep 29, 2023, 02:36 PM |
| Albers Jeffrey W. | Director | Aug 25, 2023 | Option Exercise | $1.87 | 10,000 | 18,700 | 186,050 | Aug 28, 2023, 06:23 PM |
| Albers Jeffrey W. | Director | Aug 24, 2023 | Option Exercise | $1.87 | 15,000 | 28,050 | 191,050 | Aug 28, 2023, 06:23 PM |
| Albers Jeffrey W. | Director | Aug 25, 2023 | Sale | $50.16 | 10,000 | 501,600 | 176,050 | Aug 28, 2023, 06:23 PM |
| Albers Jeffrey W. | Director | Aug 24, 2023 | Sale | $49.57 | 15,000 | 743,550 | 176,050 | Aug 28, 2023, 06:23 PM |
| Carter Percy H. | CHIEF SCIENTIFIC OFFICER | Jun 05, 2023 | Sale | $52.06 | 2,307 | 120,102 | 38,117 | Jun 07, 2023, 07:52 PM |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | Jun 05, 2023 | Sale | $52.05 | 1,404 | 73,078 | 36,878 | Jun 07, 2023, 07:48 PM |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | Mar 06, 2023 | Sale | $45.68 | 1,875 | 85,641 | 25,741 | Mar 08, 2023, 09:38 PM |
| Rossi Christina | CHIEF OPERATING OFFICER | Mar 06, 2023 | Sale | $45.67 | 3,059 | 139,715 | 55,475 | Mar 08, 2023, 09:36 PM |
| Namouni Fouad | PRESIDENT, R & D | Mar 06, 2023 | Sale | $45.68 | 1,948 | 88,977 | 65,912 | Mar 08, 2023, 09:34 PM |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | Mar 06, 2023 | Sale | $45.69 | 1,514 | 69,174 | 38,330 | Mar 08, 2023, 09:33 PM |
| Lee Philina | CHIEF COMMERCIAL OFFICER | Mar 06, 2023 | Sale | $45.68 | 1,676 | 76,555 | 31,232 | Mar 08, 2023, 09:32 PM |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | Mar 06, 2023 | Sale | $45.68 | 3,158 | 144,248 | 50,252 | Mar 08, 2023, 09:31 PM |
| Carter Percy H. | CHIEF SCIENTIFIC OFFICER | Mar 06, 2023 | Sale | $45.69 | 761 | 34,769 | 40,449 | Mar 08, 2023, 09:29 PM |
| Albers Jeffrey W. | Director | Mar 06, 2023 | Sale | $45.67 | 9,793 | 447,273 | 173,769 | Mar 08, 2023, 09:28 PM |
| McCain Tracey L | EVP AND CHIEF LEGAL OFFICER | Mar 06, 2023 | Sale | $45.68 | 3,322 | 151,743 | 52,772 | Mar 08, 2023, 09:27 PM |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | Mar 06, 2023 | Sale | $45.68 | 3,007 | 137,361 | 48,619 | Mar 08, 2023, 09:26 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Mar 06, 2023 | Sale | $45.68 | 1,126 | 51,435 | 14,210 | Mar 08, 2023, 09:25 PM |
| Haviland Kate | CHIEF EXECUTIVE OFFICER | Mar 06, 2023 | Sale | $45.69 | 6,640 | 303,354 | 125,853 | Mar 08, 2023, 09:24 PM |
| Albers Jeffrey W. | Director | Dec 05, 2022 | Option Exercise | $8.44 | 20,000 | 168,800 | 203,243 | Dec 07, 2022, 08:52 PM |
| Albers Jeffrey W. | Director | Dec 05, 2022 | Sale | $50.09 | 20,000 | 1,001,800 | 183,243 | Dec 07, 2022, 08:52 PM |
| Rossi Christina | CHIEF OPERATING OFFICER | Nov 03, 2022 | Sale | $45.24 | 533 | 24,113 | 43,435 | Nov 07, 2022, 04:08 PM |
| Haviland Kate | CHIEF EXECUTIVE OFFICER | Nov 03, 2022 | Buy | $43.98 | 1,100 | 48,378 | 92,281 | Nov 07, 2022, 04:07 PM |
| Namouni Fouad | PRESIDENT, R & D | Oct 04, 2022 | Sale | $67.30 | 3,477 | 234,002 | 52,797 | Oct 05, 2022, 06:54 PM |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | Aug 24, 2022 | Option Exercise | $15.01 | 5,000 | 75,050 | 45,836 | Aug 26, 2022, 07:09 PM |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | Aug 24, 2022 | Sale | $75.11 | 5,000 | 375,550 | 40,836 | Aug 26, 2022, 07:09 PM |
| Albers Jeffrey W. | Director | Aug 22, 2022 | Option Exercise | $15.01 | 8,410 | 126,234 | 191,653 | Aug 23, 2022, 05:53 PM |
| Albers Jeffrey W. | Director | Aug 19, 2022 | Option Exercise | $15.01 | 1,590 | 23,866 | 184,833 | Aug 23, 2022, 05:53 PM |
| Albers Jeffrey W. | Director | Aug 22, 2022 | Sale | $70.54 | 8,410 | 593,202 | 183,905 | Aug 23, 2022, 05:53 PM |
| Albers Jeffrey W. | Director | Aug 19, 2022 | Sale | $70.02 | 1,590 | 111,332 | 183,243 | Aug 23, 2022, 05:53 PM |
| Albers Jeffrey W. | Director | Aug 16, 2022 | Option Exercise | $8.44 | 20,000 | 168,800 | 203,243 | Aug 18, 2022, 07:55 PM |
| Albers Jeffrey W. | Director | Aug 16, 2022 | Sale | $68.41 | 20,000 | 1,368,253 | 196,013 | Aug 18, 2022, 07:55 PM |
| Albers Jeffrey W. | Director | Aug 08, 2022 | Option Exercise | $6.84 | 10,000 | 68,388 | 193,243 | Aug 10, 2022, 07:31 PM |
| Albers Jeffrey W. | Director | Aug 08, 2022 | Sale | $70.07 | 10,000 | 700,700 | 183,243 | Aug 10, 2022, 07:31 PM |
| Murray Christopher K. | SVP, TECHNICAL OPERATIONS | Aug 05, 2022 | Sale | $65.00 | 2,500 | 162,500 | 18,820 | Aug 08, 2022, 06:48 PM |
| Murray Christopher K. | SVP, TECHNICAL OPERATIONS | Aug 04, 2022 | Sale | $60.44 | 2,500 | 151,100 | 21,320 | Aug 08, 2022, 06:48 PM |
| Demetri George | Director | Jul 13, 2021 | Buy | $82.66 | 10 | 827 | 5,822 | Jun 30, 2022, 09:53 PM |
| Demetri George | Director | Mar 17, 2022 | Sale | $58.56 | 10 | 586 | 5,812 | Jun 30, 2022, 09:53 PM |
| Carter Percy H. | CHIEF SCIENTIFIC OFFICER | Jun 06, 2022 | Sale | $59.76 | 1,908 | 114,022 | 28,685 | Jun 08, 2022, 04:05 PM |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | Jun 07, 2022 | Sale | $60.00 | 3,155 | 189,300 | 27,296 | Jun 08, 2022, 04:05 PM |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | Jun 06, 2022 | Sale | $59.76 | 1,220 | 72,907 | 30,451 | Jun 08, 2022, 04:05 PM |
| Lydon Nicholas | Director | May 23, 2022 | Option Exercise | $19.53 | 10,909 | 213,053 | 50,584 | May 25, 2022, 04:05 PM |
| Albers Jeffrey W. | Director | May 16, 2022 | Option Exercise | $8.44 | 20,000 | 168,800 | 203,243 | May 18, 2022, 04:05 PM |
| Albers Jeffrey W. | Director | May 16, 2022 | Sale | $55.89 | 20,000 | 1,117,815 | 201,343 | May 18, 2022, 04:05 PM |
| Albers Jeffrey W. | CEO AND PRESIDENT | Apr 06, 2022 | Option Exercise | $15.01 | 5,000 | 75,050 | 188,243 | Apr 08, 2022, 04:05 PM |
| Albers Jeffrey W. | CEO AND PRESIDENT | Apr 06, 2022 | Sale | $70.11 | 5,000 | 350,550 | 183,243 | Apr 08, 2022, 04:05 PM |
| Rossi Christina | CHIEF COMMERCIAL OFFICER | Nov 03, 2021 | Sale | $110.85 | 511 | 56,644 | 43,968 | Mar 23, 2022, 04:05 PM |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | Mar 16, 2022 | Sale | $60.00 | 2,219 | 133,140 | 31,671 | Mar 18, 2022, 04:05 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Mar 10, 2022 | Sale | $57.15 | 2,339 | 133,674 | 9,616 | Mar 14, 2022, 04:05 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Mar 07, 2022 | Sale | $56.19 | 256 | 14,385 | 11,955 | Mar 08, 2022, 05:15 PM |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | Mar 03, 2022 | Sale | $60.27 | 761 | 45,865 | 12,211 | Mar 08, 2022, 05:15 PM |
| Albers Jeffrey W. | CEO AND PRESIDENT | Mar 04, 2022 | Option Exercise | $10.08 | 20,000 | 201,650 | 208,086 | Mar 08, 2022, 04:06 PM |
| Albers Jeffrey W. | CEO AND PRESIDENT | Mar 07, 2022 | Sale | $56.19 | 4,843 | 272,128 | 183,243 | Mar 08, 2022, 04:06 PM |
| Albers Jeffrey W. | CEO AND PRESIDENT | Mar 04, 2022 | Sale | $57.38 | 20,000 | 1,147,662 | 198,031 | Mar 08, 2022, 04:06 PM |
| Albers Jeffrey W. | CEO AND PRESIDENT | Mar 03, 2022 | Sale | $60.28 | 7,862 | 473,921 | 188,086 | Mar 08, 2022, 04:06 PM |
| Namouni Fouad | PRESIDENT, R & D | Mar 07, 2022 | Sale | $56.19 | 1,047 | 58,831 | 56,274 | Mar 08, 2022, 04:06 PM |
| Rossi Christina | CHIEF COMMERCIAL OFFICER | Mar 07, 2022 | Sale | $56.19 | 1,047 | 58,831 | 44,479 | Mar 08, 2022, 04:05 PM |
| Rossi Christina | CHIEF COMMERCIAL OFFICER | Mar 03, 2022 | Sale | $60.28 | 1,197 | 72,155 | 45,526 | Mar 08, 2022, 04:05 PM |
| Goldberg Mark Alan | Director | Mar 03, 2022 | Buy | $59.98 | 5,000 | 299,900 | 10,812 | Mar 07, 2022, 04:05 PM |
| Hewes L. Becker | Chief Medical Officer | Dec 15, 2021 | Option Exercise | $66.24 | 729 | 48,289 | 26,916 | Dec 17, 2021, 04:02 PM |
| Hewes L. Becker | Chief Medical Officer | Dec 15, 2021 | Sale | $100.00 | 729 | 72,900 | 26,187 | Dec 17, 2021, 04:02 PM |
| Haviland Kate | Chief Operating Officer | Dec 13, 2021 | Option Exercise | $36.05 | 1,000 | 36,050 | 54,948 | Dec 15, 2021, 04:23 PM |
| Haviland Kate | Chief Operating Officer | Dec 13, 2021 | Sale | $98.30 | 1,000 | 98,296 | 54,663 | Dec 15, 2021, 04:23 PM |
| McCain Tracey L | EVP and Chief Legal Officer | Dec 07, 2021 | Option Exercise | $28.36 | 5,000 | 141,800 | 38,441 | Dec 09, 2021, 04:01 PM |
| McCain Tracey L | EVP and Chief Legal Officer | Dec 07, 2021 | Sale | $97.30 | 5,000 | 486,490 | 34,113 | Dec 09, 2021, 04:01 PM |
| Hurley Ariel | Principal Accounting Officer | Nov 16, 2021 | Option Exercise | $8.22 | 1,950 | 16,035 | 12,047 | Nov 18, 2021, 04:06 PM |
| Hurley Ariel | Principal Accounting Officer | Nov 16, 2021 | Sale | $114.28 | 1,950 | 222,846 | 10,097 | Nov 18, 2021, 04:06 PM |
| Albers Jeffrey W. | CEO and President | Nov 15, 2021 | Option Exercise | $11.73 | 30,000 | 351,750 | 218,448 | Nov 17, 2021, 04:18 PM |
| Albers Jeffrey W. | CEO and President | Nov 15, 2021 | Sale | $114.50 | 30,000 | 3,435,099 | 196,542 | Nov 17, 2021, 04:18 PM |
| Hewes L. Becker | Chief Medical Officer | Nov 15, 2021 | Option Exercise | $66.24 | 729 | 48,289 | 26,916 | Nov 17, 2021, 04:04 PM |
| Hewes L. Becker | Chief Medical Officer | Nov 15, 2021 | Sale | $115.49 | 729 | 84,192 | 26,187 | Nov 17, 2021, 04:04 PM |
| McCain Tracey L | EVP and Chief Legal Officer | Nov 03, 2021 | Option Exercise | $28.36 | 5,000 | 141,800 | 38,274 | Nov 05, 2021, 04:01 PM |
| McCain Tracey L | EVP and Chief Legal Officer | Nov 03, 2021 | Sale | $110.56 | 5,000 | 552,812 | 34,074 | Nov 05, 2021, 04:01 PM |
| Durso-Bumpus Debra | Chief People Officer | Nov 01, 2021 | Option Exercise | $29.34 | 5,177 | 151,885 | 36,051 | Nov 03, 2021, 04:05 PM |
| Durso-Bumpus Debra | Chief People Officer | Nov 01, 2021 | Sale | $113.03 | 5,177 | 585,172 | 34,126 | Nov 03, 2021, 04:05 PM |
| Albers Jeffrey W. | CEO and President | Nov 01, 2021 | Option Exercise | $15.01 | 5,000 | 75,050 | 193,448 | Nov 03, 2021, 04:03 PM |
| Albers Jeffrey W. | CEO and President | Nov 01, 2021 | Sale | $115.16 | 5,000 | 575,800 | 188,448 | Nov 03, 2021, 04:03 PM |
| Hewes L. Becker | Chief Medical Officer | Oct 15, 2021 | Option Exercise | $66.24 | 729 | 48,289 | 26,916 | Oct 19, 2021, 04:04 PM |
| Hewes L. Becker | Chief Medical Officer | Oct 15, 2021 | Sale | $102.66 | 729 | 74,839 | 26,187 | Oct 19, 2021, 04:04 PM |
| Namouni Fouad | President, R & D | Oct 05, 2021 | Sale | $98.18 | 3,241 | 318,201 | 42,321 | Oct 07, 2021, 04:26 PM |
| Hurley Ariel | Principal Accounting Officer | Sep 23, 2021 | Option Exercise | $15.01 | 600 | 9,006 | 10,697 | Sep 27, 2021, 04:31 PM |
| Hurley Ariel | Principal Accounting Officer | Sep 23, 2021 | Sale | $110.00 | 600 | 66,000 | 10,097 | Sep 27, 2021, 04:31 PM |
| McCain Tracey L | EVP and Chief Legal Officer | Sep 23, 2021 | Option Exercise | $28.36 | 25,000 | 709,000 | 58,274 | Sep 27, 2021, 04:30 PM |
| McCain Tracey L | EVP and Chief Legal Officer | Sep 23, 2021 | Sale | $108.85 | 25,000 | 2,721,349 | 53,512 | Sep 27, 2021, 04:30 PM |
| Durso-Bumpus Debra | Chief People Officer | Sep 23, 2021 | Option Exercise | $36.05 | 848 | 30,570 | 31,722 | Sep 27, 2021, 04:28 PM |
| Durso-Bumpus Debra | Chief People Officer | Sep 23, 2021 | Sale | $110.01 | 848 | 93,288 | 30,874 | Sep 27, 2021, 04:28 PM |
| Hewes L. Becker | Chief Medical Officer | Sep 15, 2021 | Option Exercise | $66.24 | 8,750 | 579,600 | 38,020 | Sep 17, 2021, 04:19 PM |
| Hewes L. Becker | Chief Medical Officer | Sep 15, 2021 | Sale | $101.17 | 11,833 | 1,197,139 | 33,880 | Sep 17, 2021, 04:19 PM |
| Hewes L. Becker | Chief Medical Officer | Jun 02, 2021 | Sale | $89.03 | 1,292 | 115,027 | 29,270 | Sep 17, 2021, 04:14 PM |
| Hurley Ariel | Principal Accounting Officer | Sep 13, 2021 | Option Exercise | $15.01 | 600 | 9,006 | 10,697 | Sep 15, 2021, 04:14 PM |
| Hurley Ariel | Principal Accounting Officer | Sep 13, 2021 | Sale | $100.00 | 600 | 60,000 | 10,097 | Sep 15, 2021, 04:14 PM |
| Haviland Kate | Chief Operating Officer | Sep 13, 2021 | Option Exercise | $36.05 | 1,000 | 36,050 | 54,948 | Sep 15, 2021, 04:13 PM |
| Haviland Kate | Chief Operating Officer | Sep 13, 2021 | Sale | $99.94 | 1,000 | 99,936 | 54,662 | Sep 15, 2021, 04:13 PM |
| Albers Jeffrey W. | CEO and President | Aug 26, 2021 | Option Exercise | $1.87 | 16,000 | 29,920 | 188,448 | Aug 30, 2021, 04:04 PM |
| Albers Jeffrey W. | CEO and President | Aug 19, 2021 | Option Exercise | $11.07 | 25,000 | 276,700 | 197,448 | Aug 23, 2021, 04:24 PM |
| Albers Jeffrey W. | CEO and President | Aug 19, 2021 | Sale | $92.68 | 25,000 | 2,317,102 | 182,633 | Aug 23, 2021, 04:24 PM |
| Hurley Ariel | Principal Accounting Officer | Aug 17, 2021 | Option Exercise | $5.21 | 1,350 | 7,029 | 11,447 | Aug 19, 2021, 04:16 PM |
| Hurley Ariel | Principal Accounting Officer | Aug 17, 2021 | Sale | $91.93 | 1,350 | 124,106 | 10,097 | Aug 19, 2021, 04:16 PM |
| Haviland Kate | Chief Operating Officer | Jun 28, 2021 | Option Exercise | $36.05 | 1,000 | 36,050 | 54,948 | Jun 30, 2021, 04:02 PM |
| Haviland Kate | Chief Operating Officer | Jun 28, 2021 | Sale | $90.24 | 1,000 | 90,238 | 54,594 | Jun 30, 2021, 04:02 PM |
| Albers Jeffrey W. | CEO and President | May 12, 2021 | Option Exercise | $11.07 | 25,000 | 276,700 | 197,448 | May 14, 2021, 06:02 PM |
| Albers Jeffrey W. | CEO and President | May 12, 2021 | Sale | $92.69 | 25,000 | 2,317,366 | 191,784 | May 14, 2021, 06:02 PM |
| Hurley Ariel | Principal Accounting Officer | Mar 03, 2021 | Sale | $98.45 | 512 | 50,406 | 12,659 | Mar 17, 2021, 05:49 PM |
| Haviland Kate | Chief Operating Officer | Mar 15, 2021 | Option Exercise | $36.05 | 1,000 | 36,050 | 54,948 | Mar 17, 2021, 05:48 PM |
| Haviland Kate | Chief Operating Officer | Mar 15, 2021 | Sale | $105.60 | 1,000 | 105,603 | 54,942 | Mar 17, 2021, 05:48 PM |
| Durso-Bumpus Debra | Chief People Officer | Mar 04, 2021 | Sale | $86.76 | 1,693 | 146,887 | 32,458 | Mar 05, 2021, 05:53 PM |
| Hurley Ariel | Principal Accounting Officer | Mar 04, 2021 | Sale | $86.77 | 857 | 74,364 | 12,603 | Mar 05, 2021, 05:52 PM |
| Hurley Ariel | Principal Accounting Officer | Mar 03, 2021 | Sale | $98.45 | 515 | 50,702 | 12,656 | Mar 05, 2021, 05:52 PM |
| Haviland Kate | Chief Operating Officer | Mar 04, 2021 | Sale | $86.77 | 1,952 | 169,370 | 55,776 | Mar 05, 2021, 05:52 PM |
| Landsittel Michael | Chief Financial Officer | Mar 04, 2021 | Sale | $86.76 | 1,507 | 130,749 | 30,316 | Mar 05, 2021, 05:51 PM |
| McCain Tracey L | EVP and Chief Legal Officer | Mar 04, 2021 | Sale | $86.76 | 1,893 | 164,242 | 34,624 | Mar 05, 2021, 05:50 PM |
| Murray Christopher K. | SVP, Technical Operations | Mar 04, 2021 | Sale | $86.76 | 1,210 | 104,984 | 20,021 | Mar 05, 2021, 05:49 PM |
| Rossi Christina | Chief Commercial Officer | Mar 04, 2021 | Sale | $86.77 | 1,359 | 117,920 | 32,995 | Mar 05, 2021, 05:48 PM |
| Albers Jeffrey W. | CEO and President | Mar 04, 2021 | Option Exercise | $8.80 | 10,000 | 88,000 | 191,434 | Mar 05, 2021, 05:48 PM |
| Albers Jeffrey W. | CEO and President | Mar 04, 2021 | Sale | $89.28 | 18,986 | 1,695,006 | 190,334 | Mar 05, 2021, 05:48 PM |
| Hurley Ariel | Principal Accounting Officer | Mar 01, 2021 | Option Exercise | $3.09 | 1,700 | 5,258 | 14,871 | Mar 03, 2021, 12:00 AM |
| Hurley Ariel | Principal Accounting Officer | Mar 01, 2021 | Sale | $99.51 | 1,700 | 169,167 | 13,171 | Mar 03, 2021, 12:00 AM |
| Dorsch Marion | Chief Scientific Officer | Feb 22, 2021 | Option Exercise | $37.11 | 7,578 | 281,220 | 22,828 | Feb 24, 2021, 04:28 PM |
| Dorsch Marion | Chief Scientific Officer | Feb 22, 2021 | Sale | $100.00 | 7,578 | 757,800 | 15,250 | Feb 24, 2021, 04:28 PM |
| Demetri George | Director | Jan 04, 2021 | Sale | $112.15 | 758 | 85,010 | 3,562 | Jan 06, 2021, 12:00 AM |
| Goldberg Mark Alan | Director | Dec 24, 2020 | Option Exercise | $28.15 | 5,455 | 153,558 | 9,017 | Dec 28, 2020, 04:23 PM |
| Goldberg Mark Alan | Director | Dec 24, 2020 | Sale | $125.00 | 5,455 | 681,875 | 3,562 | Dec 28, 2020, 04:23 PM |
| Goldberg Mark Alan | Director | Dec 18, 2020 | Option Exercise | $28.15 | 5,454 | 153,530 | 9,016 | Dec 22, 2020, 04:14 PM |
| Goldberg Mark Alan | Director | Dec 18, 2020 | Sale | $120.00 | 5,454 | 654,480 | 3,562 | Dec 22, 2020, 04:14 PM |
| Rowland Charles A Jr | Director | Dec 17, 2020 | Option Exercise | $19.53 | 10,909 | 213,053 | 14,471 | Dec 18, 2020, 04:09 PM |
| Rowland Charles A Jr | Director | Dec 17, 2020 | Sale | $117.82 | 10,909 | 1,285,298 | 3,562 | Dec 18, 2020, 04:09 PM |
| Albers Jeffrey W. | CEO and President | Dec 14, 2020 | Option Exercise | $8.80 | 5,000 | 44,000 | 146,434 | Dec 16, 2020, 04:04 PM |
| Albers Jeffrey W. | CEO and President | Dec 14, 2020 | Sale | $119.18 | 5,000 | 595,900 | 141,434 | Dec 16, 2020, 04:04 PM |
| Boral Anthony L. | Chief Medical Officer | Dec 14, 2020 | Option Exercise | $15.01 | 10,000 | 150,100 | 38,147 | Dec 16, 2020, 04:03 PM |
| Boral Anthony L. | Chief Medical Officer | Dec 14, 2020 | Sale | $118.52 | 10,000 | 1,185,200 | 30,332 | Dec 16, 2020, 04:03 PM |
| Dorsch Marion | Chief Scientific Officer | Dec 14, 2020 | Option Exercise | $37.11 | 4,600 | 170,706 | 19,850 | Dec 16, 2020, 04:03 PM |
| Dorsch Marion | Chief Scientific Officer | Dec 14, 2020 | Sale | $119.00 | 4,600 | 547,400 | 15,250 | Dec 16, 2020, 04:03 PM |
| Goldberg Mark Alan | Director | Dec 11, 2020 | Option Exercise | $28.15 | 5,455 | 153,558 | 9,017 | Dec 15, 2020, 04:08 PM |
| Goldberg Mark Alan | Director | Dec 11, 2020 | Sale | $115.00 | 5,455 | 627,325 | 3,562 | Dec 15, 2020, 04:08 PM |
| Goldberg Mark Alan | Director | Dec 01, 2020 | Option Exercise | $28.15 | 5,454 | 153,530 | 9,016 | Dec 03, 2020, 04:10 PM |
| Goldberg Mark Alan | Director | Dec 01, 2020 | Sale | $110.00 | 5,454 | 599,940 | 3,562 | Dec 03, 2020, 04:10 PM |
| Hurley Ariel | Principal Accounting Officer | Dec 01, 2020 | Option Exercise | $8.80 | 900 | 7,920 | 10,884 | Dec 03, 2020, 04:10 PM |
| Hurley Ariel | Principal Accounting Officer | Dec 01, 2020 | Sale | $109.88 | 1,038 | 114,053 | 9,984 | Dec 03, 2020, 04:10 PM |
| Haviland Kate | Chief Operating Officer | Nov 16, 2020 | Option Exercise | $36.05 | 409 | 14,744 | 43,247 | Nov 18, 2020, 04:23 PM |
| Haviland Kate | Chief Operating Officer | Nov 16, 2020 | Sale | $100.27 | 409 | 41,010 | 42,838 | Nov 18, 2020, 04:23 PM |
| Albers Jeffrey W. | CEO and President | Nov 16, 2020 | Option Exercise | $8.80 | 20,000 | 176,000 | 161,434 | Nov 18, 2020, 04:22 PM |
| Albers Jeffrey W. | CEO and President | Nov 16, 2020 | Sale | $98.71 | 20,000 | 1,974,295 | 157,307 | Nov 18, 2020, 04:22 PM |
| Hurley Ariel | Principal Accounting Officer | Nov 16, 2020 | Option Exercise | $3.09 | 1,700 | 5,258 | 11,684 | Nov 18, 2020, 04:21 PM |
| Hurley Ariel | Principal Accounting Officer | Nov 16, 2020 | Sale | $100.92 | 1,700 | 171,564 | 9,984 | Nov 18, 2020, 04:21 PM |
| Rossi Christina | Chief Commercial Officer | Nov 03, 2020 | Sale | $99.69 | 345 | 34,393 | 20,020 | Nov 05, 2020, 05:02 PM |
| Rowland Charles A Jr | Director | Nov 03, 2020 | Option Exercise | $9.46 | 5,522 | 52,238 | 9,084 | Nov 04, 2020, 05:18 PM |
| Rowland Charles A Jr | Director | Nov 02, 2020 | Option Exercise | $9.46 | 4,478 | 42,362 | 8,040 | Nov 04, 2020, 05:18 PM |
| Rowland Charles A Jr | Director | Nov 03, 2020 | Sale | $98.73 | 5,522 | 545,196 | 8,984 | Nov 04, 2020, 05:18 PM |
| Rowland Charles A Jr | Director | Nov 02, 2020 | Sale | $99.11 | 4,478 | 443,815 | 3,562 | Nov 04, 2020, 05:18 PM |
| Boral Anthony L. | Chief Medical Officer | Oct 23, 2020 | Option Exercise | $12.70 | 9,183 | 116,667 | 28,147 | Oct 27, 2020, 04:05 PM |
| Goldberg Mark Alan | Director | Oct 19, 2020 | Option Exercise | $19.53 | 5,455 | 106,536 | 9,017 | Oct 21, 2020, 04:21 PM |
| Goldberg Mark Alan | Director | Oct 19, 2020 | Sale | $105.00 | 5,455 | 572,775 | 3,562 | Oct 21, 2020, 04:21 PM |
| Haviland Kate | Chief Operating Officer | Oct 16, 2020 | Option Exercise | $36.05 | 13,334 | 480,691 | 56,172 | Oct 20, 2020, 04:09 PM |
| Haviland Kate | Chief Operating Officer | Oct 16, 2020 | Sale | $101.23 | 13,334 | 1,349,848 | 53,163 | Oct 20, 2020, 04:09 PM |
| Hurley Ariel | Principal Accounting Officer | Oct 07, 2020 | Option Exercise | $8.80 | 600 | 5,280 | 10,584 | Oct 09, 2020, 04:06 PM |
| Hurley Ariel | Principal Accounting Officer | Oct 07, 2020 | Sale | $100.00 | 600 | 60,000 | 9,984 | Oct 09, 2020, 04:06 PM |
| Albers Jeffrey W. | CEO and President | Oct 07, 2020 | Option Exercise | $8.80 | 5,000 | 44,000 | 146,434 | Oct 09, 2020, 04:05 PM |
| Albers Jeffrey W. | CEO and President | Oct 07, 2020 | Sale | $99.17 | 5,000 | 495,850 | 141,434 | Oct 09, 2020, 04:05 PM |
| Goldberg Mark Alan | Director | Oct 07, 2020 | Option Exercise | $19.53 | 5,454 | 106,517 | 9,016 | Oct 09, 2020, 04:04 PM |
| Goldberg Mark Alan | Director | Oct 07, 2020 | Sale | $100.00 | 5,454 | 545,400 | 3,562 | Oct 09, 2020, 04:04 PM |
| Dorsch Marion | Chief Scientific Officer | Oct 06, 2020 | Option Exercise | $37.11 | 4,600 | 170,706 | 19,850 | Oct 08, 2020, 04:16 PM |
| Dorsch Marion | Chief Scientific Officer | Oct 06, 2020 | Sale | $99.00 | 4,600 | 455,400 | 15,250 | Oct 08, 2020, 04:16 PM |
| Lydon Nicholas | Director | Oct 01, 2020 | Sale | $93.08 | 9,815 | 913,595 | 43,344 | Oct 05, 2020, 04:17 PM |
| Dorsch Marion | Chief Scientific Officer | Sep 23, 2020 | Option Exercise | $37.11 | 4,600 | 170,706 | 19,850 | Sep 25, 2020, 04:27 PM |
| Dorsch Marion | Chief Scientific Officer | Sep 23, 2020 | Sale | $89.00 | 4,600 | 409,400 | 15,250 | Sep 25, 2020, 04:27 PM |
| Hurley Ariel | Principal Accounting Officer | Sep 23, 2020 | Option Exercise | $1.87 | 1,400 | 2,618 | 11,384 | Sep 25, 2020, 04:27 PM |
| Hurley Ariel | Principal Accounting Officer | Sep 23, 2020 | Sale | $90.00 | 1,400 | 126,000 | 9,984 | Sep 25, 2020, 04:27 PM |
| Durso-Bumpus Debra | Chief People Officer | Sep 23, 2020 | Option Exercise | $36.05 | 1,900 | 68,495 | 21,405 | Sep 25, 2020, 04:26 PM |
| Durso-Bumpus Debra | Chief People Officer | Sep 23, 2020 | Sale | $90.02 | 1,900 | 171,038 | 19,505 | Sep 25, 2020, 04:26 PM |
| Demetri George | Director | Sep 22, 2020 | Sale | $85.00 | 1,704 | 144,840 | 4,320 | Sep 24, 2020, 04:22 PM |
| Boral Anthony L. | Chief Medical Officer | Sep 22, 2020 | Option Exercise | $15.01 | 6,864 | 103,029 | 25,828 | Sep 24, 2020, 04:22 PM |
| Boral Anthony L. | Chief Medical Officer | Sep 22, 2020 | Sale | $82.33 | 6,864 | 565,113 | 18,964 | Sep 24, 2020, 04:22 PM |
| Haviland Kate | Chief Operating Officer | Sep 22, 2020 | Option Exercise | $16.28 | 3,143 | 51,168 | 45,981 | Sep 24, 2020, 04:19 PM |
| Haviland Kate | Chief Operating Officer | Sep 22, 2020 | Sale | $85.49 | 3,143 | 268,695 | 42,838 | Sep 24, 2020, 04:19 PM |
| Boral Anthony L. | Chief Medical Officer | Sep 17, 2020 | Option Exercise | $11.45 | 23,136 | 264,945 | 42,100 | Sep 21, 2020, 04:22 PM |
| Boral Anthony L. | Chief Medical Officer | Sep 17, 2020 | Sale | $80.00 | 23,136 | 1,850,880 | 18,964 | Sep 21, 2020, 04:22 PM |
| Lydon Nicholas | Director | Sep 17, 2020 | Sale | $80.00 | 500 | 40,000 | 47,240 | Sep 21, 2020, 04:21 PM |
| Albers Jeffrey W. | CEO and President | Aug 19, 2020 | Option Exercise | $8.80 | 20,000 | 176,000 | 161,434 | Aug 21, 2020, 04:22 PM |
| Albers Jeffrey W. | CEO and President | Aug 19, 2020 | Sale | $75.02 | 20,000 | 1,500,438 | 150,031 | Aug 21, 2020, 04:22 PM |
| Hurley Ariel | Principal Accounting Officer | Aug 17, 2020 | Option Exercise | $1.87 | 700 | 1,309 | 10,684 | Aug 19, 2020, 04:52 PM |
| Hurley Ariel | Principal Accounting Officer | Aug 17, 2020 | Sale | $75.00 | 700 | 52,500 | 9,984 | Aug 19, 2020, 04:52 PM |
| Lydon Nicholas | Director | Jul 06, 2020 | Sale | $80.45 | 26,007 | 2,092,351 | 48,340 | Jul 08, 2020, 04:25 PM |
| Lydon Nicholas | Director | Jul 02, 2020 | Sale | $80.13 | 2,825 | 226,367 | 73,747 | Jul 06, 2020, 06:30 PM |
| Lydon Nicholas | Director | Jul 01, 2020 | Sale | $80.21 | 1,300 | 104,273 | 76,572 | Jul 06, 2020, 06:30 PM |
| Lydon Nicholas | Director | Jun 23, 2020 | Sale | $80.00 | 400 | 32,000 | 75,622 | Jun 25, 2020, 04:10 PM |
| Durso-Bumpus Debra | Chief People Officer | Jun 22, 2020 | Option Exercise | $36.05 | 2,300 | 82,915 | 21,805 | Jun 24, 2020, 04:14 PM |
| Durso-Bumpus Debra | Chief People Officer | Jun 22, 2020 | Sale | $80.07 | 2,300 | 184,161 | 19,505 | Jun 24, 2020, 04:14 PM |
| Lydon Nicholas | Director | Jun 22, 2020 | Sale | $80.29 | 13,017 | 1,045,135 | 76,022 | Jun 23, 2020, 04:13 PM |
| Dorsch Marion | Chief Scientific Officer | Jun 19, 2020 | Option Exercise | $37.11 | 4,600 | 170,706 | 19,850 | Jun 23, 2020, 04:10 PM |
| Dorsch Marion | Chief Scientific Officer | Jun 19, 2020 | Sale | $79.00 | 4,600 | 363,400 | 15,250 | Jun 23, 2020, 04:10 PM |
| Durso-Bumpus Debra | Chief People Officer | Jun 18, 2020 | Option Exercise | $18.00 | 2,500 | 45,000 | 22,005 | Jun 22, 2020, 04:21 PM |
| Durso-Bumpus Debra | Chief People Officer | Jun 18, 2020 | Sale | $75.18 | 2,500 | 187,950 | 19,505 | Jun 22, 2020, 04:21 PM |
| Hurley Ariel | Principal Accounting Officer | Jun 09, 2020 | Option Exercise | $1.87 | 700 | 1,309 | 10,684 | Jun 11, 2020, 05:20 PM |
| Hurley Ariel | Principal Accounting Officer | Jun 09, 2020 | Sale | $75.00 | 700 | 52,500 | 9,984 | Jun 11, 2020, 05:20 PM |
| Hurley Ariel | Principal Accounting Officer | Jun 02, 2020 | Sale | $66.03 | 235 | 15,517 | 9,984 | Jun 04, 2020, 04:37 PM |
| Albers Jeffrey W. | CEO and President | May 12, 2020 | Option Exercise | $8.80 | 20,000 | 176,000 | 161,434 | May 14, 2020, 04:38 PM |
| Albers Jeffrey W. | CEO and President | May 12, 2020 | Sale | $64.67 | 20,000 | 1,293,427 | 155,284 | May 14, 2020, 04:38 PM |
| Dorsch Marion | Chief Scientific Officer | Mar 23, 2020 | Sale | $52.49 | 1,214 | 63,726 | 16,265 | Mar 25, 2020, 04:22 PM |
| Albers Jeffrey W. | CEO and President | Mar 23, 2020 | Option Exercise | $5.32 | 40,000 | 212,846 | 161,434 | Mar 25, 2020, 04:22 PM |
| Albers Jeffrey W. | CEO and President | Mar 23, 2020 | Sale | $52.10 | 20,000 | 1,041,922 | 160,950 | Mar 25, 2020, 04:22 PM |
| Hurley Ariel | Principal Accounting Officer | Mar 09, 2020 | Sale | $51.94 | 253 | 13,141 | 9,984 | Mar 11, 2020, 04:32 PM |
| Albers Jeffrey W. | CEO and President | Mar 09, 2020 | Sale | $51.97 | 2,277 | 118,336 | 121,434 | Mar 11, 2020, 04:31 PM |
| Boral Anthony L. | Chief Medical Officer | Mar 09, 2020 | Sale | $51.97 | 536 | 27,856 | 18,964 | Mar 11, 2020, 04:31 PM |
| Dorsch Marion | Chief Scientific Officer | Mar 09, 2020 | Sale | $51.99 | 536 | 27,867 | 16,464 | Mar 11, 2020, 04:30 PM |
| Durso-Bumpus Debra | Chief People Officer | Mar 09, 2020 | Sale | $51.94 | 432 | 22,438 | 19,505 | Mar 11, 2020, 04:30 PM |
| Haviland Kate | Chief Operating Officer | Mar 09, 2020 | Sale | $51.98 | 671 | 34,879 | 42,838 | Mar 11, 2020, 04:29 PM |
| Landsittel Michael | Chief Financial Officer | Mar 09, 2020 | Sale | $51.97 | 400 | 20,788 | 17,350 | Mar 11, 2020, 04:29 PM |
| McCain Tracey L | EVP and Chief Legal Officer | Mar 09, 2020 | Sale | $51.98 | 617 | 32,072 | 21,683 | Mar 11, 2020, 04:28 PM |
| Murray Christopher K. | SVP, Technical Operations | Mar 09, 2020 | Sale | $51.94 | 402 | 20,880 | 13,848 | Mar 11, 2020, 04:28 PM |
| Rossi Christina | Chief Commercial Officer | Mar 09, 2020 | Sale | $51.96 | 135 | 7,015 | 20,365 | Mar 11, 2020, 04:27 PM |
| Haviland Kate | Chief Operating Officer | Mar 03, 2020 | Option Exercise | $16.28 | 4,644 | 75,604 | 43,509 | Mar 03, 2020, 07:12 PM |
| Demetri George | Director | Jan 10, 2020 | Sale | $85.00 | 568 | 48,280 | 2,462 | Jan 14, 2020, 04:48 PM |
| Haviland Kate | Chief Operating Officer | Jan 10, 2020 | Option Exercise | $16.28 | 7,763 | 126,382 | 23,628 | Jan 14, 2020, 04:47 PM |
| Haviland Kate | Chief Operating Officer | Jan 10, 2020 | Sale | $85.16 | 7,763 | 661,097 | 15,865 | Jan 14, 2020, 04:47 PM |
| Demetri George | Director | Jan 07, 2020 | Sale | $80.59 | 1,705 | 137,406 | 3,030 | Jan 09, 2020, 04:10 PM |
| Dorsch Marion | Chief Scientific Officer | Dec 19, 2019 | Option Exercise | $37.11 | 4,600 | 170,706 | 4,600 | Dec 23, 2019, 05:32 PM |
| Dorsch Marion | Chief Scientific Officer | Dec 19, 2019 | Sale | $79.00 | 4,600 | 363,400 | 0 | Dec 23, 2019, 05:32 PM |
| Boral Anthony L. | Chief Medical Officer | Dec 17, 2019 | Option Exercise | $8.80 | 10,000 | 88,000 | 10,000 | Dec 19, 2019, 04:38 PM |
| Boral Anthony L. | Chief Medical Officer | Dec 17, 2019 | Sale | $76.57 | 10,000 | 765,713 | 3,930 | Dec 19, 2019, 04:38 PM |
| Hurley Ariel | Principal Accounting Officer | Dec 16, 2019 | Option Exercise | $1.87 | 415 | 776 | 415 | Dec 18, 2019, 04:33 PM |
| Hurley Ariel | Principal Accounting Officer | Dec 16, 2019 | Sale | $75.00 | 415 | 31,125 | 0 | Dec 18, 2019, 04:33 PM |
| Hurley Ariel | Principal Accounting Officer | Dec 04, 2019 | Sale | $77.25 | 192 | 14,832 | 0 | Dec 06, 2019, 04:32 PM |
| Albers Jeffrey W. | CEO and President | Nov 18, 2019 | Option Exercise | $2.56 | 20,000 | 51,260 | 68,961 | Nov 20, 2019, 05:07 PM |
| Albers Jeffrey W. | CEO and President | Nov 08, 2019 | Sale | $74.56 | 11,744 | 875,633 | 48,961 | Nov 20, 2019, 05:07 PM |
| Albers Jeffrey W. | CEO and President | Nov 18, 2019 | Sale | $75.42 | 8,256 | 622,652 | 68,361 | Nov 20, 2019, 05:07 PM |
| Hurley Ariel | Principal Accounting Officer | Nov 15, 2019 | Option Exercise | $1.87 | 415 | 776 | 415 | Nov 19, 2019, 04:16 PM |
| Hurley Ariel | Principal Accounting Officer | Nov 15, 2019 | Sale | $75.00 | 415 | 31,125 | 0 | Nov 19, 2019, 04:16 PM |
| Albers Jeffrey W. | CEO and President | Oct 30, 2019 | Option Exercise | $1.87 | 20,000 | 37,400 | 48,961 | Oct 30, 2019, 04:32 PM |
| Hurley Ariel | Principal Accounting Officer | Oct 17, 2019 | Option Exercise | $1.87 | 415 | 776 | 415 | Oct 21, 2019, 04:33 PM |
| Hurley Ariel | Principal Accounting Officer | Oct 17, 2019 | Sale | $75.00 | 415 | 31,125 | 0 | Oct 21, 2019, 04:33 PM |
| Hurley Ariel | Principal Accounting Officer | Sep 16, 2019 | Option Exercise | $1.87 | 415 | 776 | 415 | Sep 18, 2019, 04:24 PM |
| Hurley Ariel | Principal Accounting Officer | Sep 16, 2019 | Sale | $78.14 | 415 | 32,428 | 0 | Sep 18, 2019, 04:24 PM |
| Boral Anthony L. | Chief Medical Officer | Aug 20, 2019 | Option Exercise | $8.80 | 1,300 | 11,440 | 1,300 | Aug 22, 2019, 04:35 PM |
| Boral Anthony L. | Chief Medical Officer | Aug 21, 2019 | Option Exercise | $8.80 | 8,700 | 76,560 | 8,700 | Aug 22, 2019, 04:35 PM |
| Boral Anthony L. | Chief Medical Officer | Aug 20, 2019 | Sale | $80.44 | 1,300 | 104,572 | 0 | Aug 22, 2019, 04:35 PM |
| Boral Anthony L. | Chief Medical Officer | Aug 21, 2019 | Sale | $80.01 | 8,700 | 696,087 | 0 | Aug 22, 2019, 04:35 PM |
| Haviland Kate | Chief Operating Officer | Aug 19, 2019 | Option Exercise | $16.28 | 95 | 1,547 | 15,960 | Aug 21, 2019, 04:18 PM |
| Haviland Kate | Chief Operating Officer | Aug 19, 2019 | Sale | $85.00 | 95 | 8,075 | 15,865 | Aug 21, 2019, 04:18 PM |
| Albers Jeffrey W. | CEO and President | Aug 19, 2019 | Option Exercise | $1.87 | 20,000 | 37,400 | 48,961 | Aug 21, 2019, 04:17 PM |
| Albers Jeffrey W. | CEO and President | Aug 19, 2019 | Sale | $81.73 | 20,000 | 1,634,661 | 48,861 | Aug 21, 2019, 04:17 PM |
| Hurley Ariel | Principal Accounting Officer | Aug 15, 2019 | Option Exercise | $1.87 | 415 | 776 | 415 | Aug 19, 2019, 04:35 PM |
| Hurley Ariel | Principal Accounting Officer | Aug 15, 2019 | Sale | $84.02 | 415 | 34,868 | 0 | Aug 19, 2019, 04:35 PM |
| COATS LONNEL | Director | Aug 15, 2019 | Option Exercise | $15.01 | 10,000 | 150,100 | 10,000 | Aug 19, 2019, 04:34 PM |
| COATS LONNEL | Director | Aug 15, 2019 | Sale | $82.40 | 10,000 | 824,007 | 7,298 | Aug 19, 2019, 04:34 PM |
| Hurley Ariel | Principal Accounting Officer | Jul 19, 2019 | Option Exercise | $8.80 | 115 | 1,012 | 115 | Jul 23, 2019, 06:23 PM |
| Hurley Ariel | Principal Accounting Officer | Jul 19, 2019 | Sale | $100.00 | 115 | 11,500 | 0 | Jul 23, 2019, 06:23 PM |
| Haviland Kate | Chief Operating Officer | Jul 16, 2019 | Option Exercise | $16.28 | 11,562 | 188,229 | 17,436 | Jul 18, 2019, 07:53 PM |
| Haviland Kate | Chief Operating Officer | Jul 16, 2019 | Sale | $95.47 | 1,571 | 149,989 | 16,214 | Jul 18, 2019, 07:53 PM |
| Hurley Ariel | Principal Accounting Officer | Jul 15, 2019 | Option Exercise | $1.87 | 830 | 1,552 | 830 | Jul 17, 2019, 04:26 PM |
| Hurley Ariel | Principal Accounting Officer | Jul 15, 2019 | Sale | $94.98 | 830 | 78,833 | 0 | Jul 17, 2019, 04:26 PM |
| Boral Anthony L. | Chief Medical Officer | Jul 08, 2019 | Option Exercise | $8.80 | 10,000 | 88,000 | 10,000 | Jul 10, 2019, 04:45 PM |
| Boral Anthony L. | Chief Medical Officer | Jul 08, 2019 | Sale | $93.88 | 10,000 | 938,756 | 4,785 | Jul 10, 2019, 04:45 PM |
| Borisy Alexis | Director | Jun 27, 2019 | Option Exercise | $32.78 | 21,818 | 715,085 | 82,724 | Jul 01, 2019, 07:23 PM |
| Borisy Alexis | Director | Jun 27, 2019 | Sale | $92.01 | 21,818 | 2,007,446 | 61,874 | Jul 01, 2019, 07:23 PM |
| Rowland Charles A Jr | Director | Jun 20, 2019 | Option Exercise | $9.46 | 11,818 | 111,798 | 11,818 | Jun 24, 2019, 08:08 PM |
| Rowland Charles A Jr | Director | Jun 20, 2019 | Sale | $95.15 | 11,818 | 1,124,462 | 10,871 | Jun 24, 2019, 08:08 PM |
| Dorsch Marion | Chief Scientific Officer | Jun 17, 2019 | Option Exercise | $37.11 | 4,600 | 170,706 | 4,600 | Jun 19, 2019, 06:08 PM |
| Dorsch Marion | Chief Scientific Officer | Jun 17, 2019 | Sale | $99.00 | 4,600 | 455,400 | 0 | Jun 19, 2019, 06:08 PM |
| Haviland Kate | Chief Operating Officer | Jun 17, 2019 | Option Exercise | $25.65 | 11,952 | 306,595 | 17,826 | Jun 19, 2019, 06:08 PM |
| Haviland Kate | Chief Operating Officer | Jun 17, 2019 | Sale | $96.46 | 11,952 | 1,152,870 | 16,893 | Jun 19, 2019, 06:08 PM |
| Albers Jeffrey W. | CEO and President | Jun 17, 2019 | Option Exercise | $1.87 | 5,000 | 9,350 | 33,961 | Jun 19, 2019, 06:07 PM |
| Albers Jeffrey W. | CEO and President | Jun 17, 2019 | Sale | $99.06 | 5,000 | 495,300 | 28,961 | Jun 19, 2019, 06:07 PM |
| Demetri George | Director | Jun 17, 2019 | Sale | $98.49 | 1,136 | 111,890 | 5,303 | Jun 19, 2019, 06:06 PM |
| Hurley Ariel | Principal Accounting Officer | Jun 17, 2019 | Option Exercise | $4.71 | 1,405 | 6,612 | 1,405 | Jun 19, 2019, 06:05 PM |
| Hurley Ariel | Principal Accounting Officer | Jun 17, 2019 | Sale | $98.22 | 1,405 | 138,002 | 575 | Jun 19, 2019, 06:05 PM |
| Demetri George | Director | Jun 13, 2019 | Sale | $90.00 | 568 | 51,120 | 5,871 | Jun 17, 2019, 05:12 PM |
| Lydon Nicholas | Director | Jun 13, 2019 | Sale | $90.36 | 25,000 | 2,259,000 | 127,727 | Jun 17, 2019, 05:11 PM |
| Hurley Ariel | Principal Accounting Officer | Jun 13, 2019 | Option Exercise | $1.87 | 1,660 | 3,104 | 1,660 | Jun 14, 2019, 06:01 PM |
| Hurley Ariel | Principal Accounting Officer | Jun 12, 2019 | Option Exercise | $1.87 | 830 | 1,552 | 830 | Jun 14, 2019, 06:01 PM |
| Hurley Ariel | Principal Accounting Officer | Jun 12, 2019 | Sale | $85.00 | 1,073 | 91,205 | 0 | Jun 14, 2019, 06:01 PM |
| Hurley Ariel | Principal Accounting Officer | Jun 13, 2019 | Sale | $90.00 | 1,660 | 149,400 | 0 | Jun 14, 2019, 06:01 PM |
| Lydon Nicholas | Director | Jun 12, 2019 | Sale | $84.77 | 25,000 | 2,119,162 | 166,527 | Jun 14, 2019, 06:00 PM |
| Albers Jeffrey W. | CEO and President | Jun 12, 2019 | Option Exercise | $1.87 | 20,000 | 37,400 | 48,961 | Jun 14, 2019, 06:00 PM |
| Albers Jeffrey W. | CEO and President | Jun 12, 2019 | Sale | $84.75 | 20,000 | 1,694,906 | 39,770 | Jun 14, 2019, 06:00 PM |
| Albers Jeffrey W. | CEO and President | Mar 15, 2019 | Option Exercise | $1.87 | 20,000 | 37,400 | 48,961 | Mar 19, 2019, 05:25 PM |
| Albers Jeffrey W. | CEO and President | Mar 15, 2019 | Sale | $86.39 | 20,000 | 1,727,884 | 44,510 | Mar 19, 2019, 05:25 PM |
| Hurley Ariel | Principal Accounting Officer | Mar 15, 2019 | Option Exercise | $1.87 | 415 | 776 | 415 | Mar 19, 2019, 05:23 PM |
| Hurley Ariel | Principal Accounting Officer | Mar 15, 2019 | Sale | $85.55 | 415 | 35,503 | 0 | Mar 19, 2019, 05:23 PM |
| Dorsch Marion | Chief Scientific Officer | Mar 04, 2019 | Option Exercise | $37.11 | 2,300 | 85,353 | 2,300 | Mar 06, 2019, 05:04 PM |
| Dorsch Marion | Chief Scientific Officer | Mar 04, 2019 | Sale | $84.66 | 2,300 | 194,723 | 2,005 | Mar 06, 2019, 05:04 PM |
| Haviland Kate | Chief Operating Officer | Mar 01, 2019 | Option Exercise | $23.13 | 21,644 | 500,639 | 27,518 | Mar 05, 2019, 05:31 PM |
| Haviland Kate | Chief Operating Officer | Mar 01, 2019 | Sale | $85.05 | 21,644 | 1,840,822 | 5,874 | Mar 05, 2019, 05:31 PM |
| Albers Jeffrey W. | CEO and President | Nov 19, 2018 | Option Exercise | $1.87 | 28,961 | 54,157 | 28,961 | Nov 21, 2018, 07:20 AM |
| Albers Jeffrey W. | CEO and President | Nov 05, 2018 | Option Exercise | $1.87 | 20,000 | 37,400 | 20,000 | Nov 07, 2018, 04:25 PM |
| Albers Jeffrey W. | CEO and President | Nov 05, 2018 | Sale | $63.49 | 20,000 | 1,269,709 | 18,900 | Nov 07, 2018, 04:25 PM |
| Dorsch Marion | Chief Scientific Officer | Sep 17, 2018 | Option Exercise | $37.11 | 2,300 | 85,353 | 2,300 | Sep 19, 2018, 04:08 PM |
| Dorsch Marion | Chief Scientific Officer | Sep 17, 2018 | Sale | $70.47 | 2,300 | 162,092 | 2,000 | Sep 19, 2018, 04:08 PM |
| Albers Jeffrey W. | CEO and President | Aug 06, 2018 | Option Exercise | $1.87 | 20,000 | 37,400 | 20,000 | Aug 08, 2018, 04:08 PM |
| Albers Jeffrey W. | CEO and President | Aug 06, 2018 | Sale | $70.59 | 20,000 | 1,411,897 | 13,821 | Aug 08, 2018, 04:08 PM |
| Albers Jeffrey W. | CEO and President | May 07, 2018 | Option Exercise | $1.87 | 20,000 | 37,400 | 20,000 | May 09, 2018, 04:29 PM |
| Albers Jeffrey W. | CEO and President | May 07, 2018 | Sale | $78.90 | 20,000 | 1,578,091 | 8,320 | May 09, 2018, 04:29 PM |
| Demetri George | Director | Mar 19, 2018 | Sale | $100.09 | 5,492 | 549,672 | 10,231 | Mar 21, 2018, 05:04 PM |
| Haviland Kate | Chief Business Officer | Mar 16, 2018 | Option Exercise | $28.42 | 4,071 | 115,701 | 9,945 | Mar 20, 2018, 08:02 PM |
| Haviland Kate | Chief Business Officer | Mar 16, 2018 | Sale | $100.75 | 4,071 | 410,138 | 9,445 | Mar 20, 2018, 08:02 PM |
| Dorsch Marion | Chief Scientific Officer | Mar 15, 2018 | Option Exercise | $37.11 | 2,300 | 85,353 | 2,300 | Mar 19, 2018, 05:06 PM |
| Dorsch Marion | Chief Scientific Officer | Mar 15, 2018 | Sale | $100.07 | 2,300 | 230,161 | 0 | Mar 19, 2018, 05:06 PM |
| Albers Jeffrey W. | CEO and President | Mar 02, 2018 | Option Exercise | $1.87 | 20,000 | 37,400 | 20,000 | Mar 06, 2018, 04:55 PM |
| Albers Jeffrey W. | CEO and President | Mar 02, 2018 | Sale | $92.57 | 20,000 | 1,851,463 | 13,978 | Mar 06, 2018, 04:55 PM |
| Haviland Kate | Chief Business Officer | Mar 01, 2018 | Option Exercise | $36.05 | 2,800 | 100,940 | 8,674 | Mar 05, 2018, 06:07 PM |
| Haviland Kate | Chief Business Officer | Mar 01, 2018 | Sale | $90.00 | 2,800 | 252,000 | 5,874 | Mar 05, 2018, 06:07 PM |
| Lydon Nicholas | Director | Feb 28, 2018 | Sale | $87.89 | 25,000 | 2,197,356 | 193,131 | Mar 02, 2018, 05:15 PM |
| Haviland Kate | Chief Business Officer | Feb 27, 2018 | Option Exercise | $36.05 | 3,200 | 115,360 | 9,074 | Mar 01, 2018, 05:12 PM |
| Haviland Kate | Chief Business Officer | Feb 27, 2018 | Sale | $88.20 | 3,200 | 282,236 | 8,874 | Mar 01, 2018, 05:12 PM |
| McCain Tracey L | EVP and Chief Legal Officer | Feb 27, 2018 | Option Exercise | $28.36 | 10,000 | 283,600 | 10,000 | Mar 01, 2018, 05:08 PM |
| McCain Tracey L | EVP and Chief Legal Officer | Feb 27, 2018 | Sale | $88.34 | 10,000 | 883,450 | 9,900 | Mar 01, 2018, 05:08 PM |
| Demetri George | Director | Feb 27, 2018 | Sale | $88.29 | 6,250 | 551,805 | 17,981 | Mar 01, 2018, 05:06 PM |
| LYNCH DANIEL | Director | Feb 14, 2018 | Sale | $80.42 | 12,500 | 1,005,250 | 174,342 | Feb 16, 2018, 06:52 PM |
| LYNCH DANIEL | Director | Feb 12, 2018 | Sale | $74.84 | 17,500 | 1,309,668 | 202,812 | Feb 14, 2018, 05:27 PM |
| Haviland Kate | Chief Business Officer | Feb 12, 2018 | Option Exercise | $16.28 | 6,775 | 110,297 | 12,649 | Feb 14, 2018, 05:23 PM |
| Haviland Kate | Chief Business Officer | Feb 12, 2018 | Sale | $74.93 | 6,775 | 507,619 | 11,749 | Feb 14, 2018, 05:23 PM |
| Dorsch Marion | Chief Scientific Officer | Nov 22, 2017 | Option Exercise | $37.11 | 9,166 | 340,150 | 9,166 | Nov 24, 2017, 06:00 PM |
| Dorsch Marion | Chief Scientific Officer | Nov 22, 2017 | Sale | $70.00 | 9,166 | 641,620 | 0 | Nov 24, 2017, 06:00 PM |
| Dorsch Marion | Chief Scientific Officer | Nov 21, 2017 | Sale | $64.44 | 500 | 32,220 | 0 | Nov 24, 2017, 05:54 PM |
| Dorsch Marion | Chief Scientific Officer | Nov 21, 2017 | Option Exercise | $37.11 | 18,334 | 680,375 | 18,334 | Nov 22, 2017, 05:55 PM |
| Dorsch Marion | Chief Scientific Officer | Nov 21, 2017 | Sale | $65.45 | 18,334 | 1,200,013 | 16,733 | Nov 22, 2017, 05:55 PM |
| Haviland Kate | Chief Business Officer | Nov 21, 2017 | Option Exercise | $16.28 | 5,874 | 95,629 | 5,874 | Nov 22, 2017, 05:52 PM |
| LYNCH DANIEL | Director | Nov 15, 2017 | Sale | $63.38 | 5,000 | 316,898 | 207,742 | Nov 17, 2017, 04:32 PM |
| Boral Anthony L. | Chief Medical Officer | Nov 06, 2017 | Option Exercise | $8.80 | 5,000 | 44,000 | 5,000 | Nov 08, 2017, 04:21 PM |
| Boral Anthony L. | Chief Medical Officer | Nov 06, 2017 | Sale | $70.40 | 5,000 | 352,022 | 4,800 | Nov 08, 2017, 04:21 PM |
| Albers Jeffrey W. | CEO and President | Nov 06, 2017 | Option Exercise | $1.87 | 24,514 | 45,841 | 30,000 | Nov 08, 2017, 04:21 PM |
| Albers Jeffrey W. | CEO and President | Nov 06, 2017 | Sale | $70.31 | 30,000 | 2,109,251 | 29,600 | Nov 08, 2017, 04:21 PM |
| Haviland Kate | Chief Business Officer | Oct 05, 2017 | Option Exercise | $16.28 | 5,449 | 88,710 | 5,449 | Oct 10, 2017, 05:19 PM |
| Haviland Kate | Chief Business Officer | Oct 05, 2017 | Sale | $66.44 | 5,449 | 362,033 | 4,564 | Oct 10, 2017, 05:19 PM |
| Haviland Kate | Chief Business Officer | Sep 18, 2017 | Option Exercise | $16.28 | 6,356 | 103,476 | 6,356 | Sep 20, 2017, 05:39 PM |
| Haviland Kate | Chief Business Officer | Sep 18, 2017 | Sale | $60.03 | 6,356 | 381,551 | 0 | Sep 20, 2017, 05:39 PM |
| LYNCH DANIEL | Director | Sep 18, 2017 | Sale | $60.00 | 2,500 | 150,000 | 209,342 | Sep 20, 2017, 05:37 PM |
| Boral Anthony L. | Chief Medical Officer | Aug 09, 2017 | Option Exercise | $8.80 | 5,000 | 44,000 | 5,000 | Aug 11, 2017, 04:54 PM |
| Boral Anthony L. | Chief Medical Officer | Aug 09, 2017 | Sale | $48.60 | 5,000 | 242,986 | 3,185 | Aug 11, 2017, 04:54 PM |
| Albers Jeffrey W. | CEO and President | Aug 08, 2017 | Sale | $50.70 | 10,000 | 507,000 | 5,486 | Aug 09, 2017, 06:18 PM |
| Albers Jeffrey W. | CEO and President | Aug 07, 2017 | Sale | $49.08 | 20,000 | 981,637 | 18,272 | Aug 09, 2017, 06:18 PM |
| LYNCH DANIEL | Director | Jul 05, 2017 | Sale | $55.06 | 7,500 | 412,950 | 211,842 | Jul 07, 2017, 04:37 PM |
| Haviland Kate | Chief Business Officer | Jul 05, 2017 | Option Exercise | $16.28 | 7,265 | 118,274 | 7,265 | Jul 07, 2017, 04:36 PM |
| Haviland Kate | Chief Business Officer | Jul 05, 2017 | Sale | $54.66 | 7,265 | 397,077 | 2,952 | Jul 07, 2017, 04:36 PM |
| Boral Anthony L. | Chief Medical Officer | Jun 28, 2017 | Option Exercise | $8.80 | 10,000 | 88,000 | 10,000 | Jun 30, 2017, 06:20 PM |
| Boral Anthony L. | Chief Medical Officer | Jun 28, 2017 | Sale | $50.47 | 10,000 | 504,750 | 5,414 | Jun 30, 2017, 06:20 PM |
| LYNCH DANIEL | Director | Jun 28, 2017 | Sale | $50.28 | 32,500 | 1,633,977 | 243,941 | Jun 30, 2017, 06:19 PM |
| Albers Jeffrey W. | CEO and President | Jun 28, 2017 | Sale | $50.47 | 20,000 | 1,009,394 | 47,920 | Jun 30, 2017, 06:18 PM |
| Haviland Kate | Chief Business Officer | Jun 28, 2017 | Option Exercise | $16.28 | 6,357 | 103,492 | 6,357 | Jun 30, 2017, 06:18 PM |
| Haviland Kate | Chief Business Officer | Jun 28, 2017 | Sale | $50.00 | 6,357 | 317,850 | 0 | Jun 30, 2017, 06:18 PM |
| Haviland Kate | Chief Business Officer | Mar 14, 2017 | Option Exercise | $16.28 | 12,714 | 206,984 | 12,714 | Jun 30, 2017, 06:16 PM |
| Haviland Kate | Chief Business Officer | Mar 14, 2017 | Sale | $40.01 | 12,714 | 508,687 | 0 | Jun 30, 2017, 06:16 PM |
| LEVIN MARK J | 10% Owner | Mar 16, 2017 | Sale | $40.88 | 30,000 | 1,226,412 | 116,444 | Mar 20, 2017, 04:21 PM |
| Lydon Nicholas | Director | Mar 14, 2017 | Sale | $40.05 | 70,000 | 2,803,724 | 204,127 | Mar 16, 2017, 05:37 PM |
| Haviland Kate | Chief Business Officer | Mar 14, 2017 | Option Exercise | $16.28 | 12,714 | 206,984 | 12,714 | Mar 16, 2017, 05:36 PM |
| Haviland Kate | Chief Business Officer | Mar 14, 2017 | Sale | $40.01 | 12,714 | 508,687 | 0 | Mar 16, 2017, 05:36 PM |
| Albers Jeffrey W. | CEO and President | Mar 14, 2017 | Sale | $40.03 | 20,000 | 800,516 | 56,466 | Mar 16, 2017, 05:35 PM |
| LYNCH DANIEL | Director | Mar 14, 2017 | Sale | $40.12 | 7,500 | 300,900 | 250,119 | Mar 16, 2017, 05:34 PM |
| Third Rock Ventures II, L.P. | 10% Owner | Feb 07, 2017 | Sale | $35.28 | 1,000,000 | 35,275,002 | 4,453,753 | Feb 09, 2017, 05:21 PM |
| STARR KEVIN P | 10% Owner | Dec 19, 2016 | Sale | $28.19 | 106,489 | 3,002,351 | 0 | Dec 21, 2016, 06:44 PM |
| LYNCH DANIEL | Director | Dec 01, 2016 | Sale | $30.02 | 200 | 6,004 | 255,694 | Dec 05, 2016, 06:22 AM |
| LYNCH DANIEL | Director | Nov 01, 2016 | Sale | $30.04 | 1,700 | 51,068 | 255,894 | Nov 03, 2016, 04:17 PM |
| LYNCH DANIEL | Director | Oct 13, 2016 | Sale | $30.02 | 21,800 | 654,436 | 257,594 | Oct 17, 2016, 05:42 PM |
| Albers Jeffrey W. | CEO and President | Aug 08, 2016 | Sale | $22.86 | 17,000 | 388,663 | 76,494 | Aug 10, 2016, 04:50 PM |
| Albers Jeffrey W. | CEO and President | Jun 03, 2016 | Sale | $20.03 | 17,000 | 340,510 | 92,486 | Jun 07, 2016, 04:21 PM |
| Lengauer Christoph | Chief Scientific Officer | Apr 13, 2016 | Sale | $20.01 | 15,872 | 317,599 | 56,657 | Apr 14, 2016, 05:55 PM |
| Lengauer Christoph | Chief Scientific Officer | Apr 12, 2016 | Sale | $20.01 | 10,316 | 206,423 | 72,529 | Apr 13, 2016, 04:20 PM |
| Lengauer Christoph | Chief Scientific Officer | Apr 11, 2016 | Sale | $20.30 | 8,537 | 173,301 | 82,845 | Apr 13, 2016, 04:20 PM |
| Albers Jeffrey W. | CEO and President | Apr 06, 2016 | Sale | $20.42 | 17,000 | 347,140 | 109,486 | Apr 08, 2016, 04:14 PM |
| Lengauer Christoph | Chief Scientific Officer | Mar 24, 2016 | Option Exercise | $1.62 | 19,167 | 31,030 | 91,382 | Mar 28, 2016, 05:22 PM |
| Lengauer Christoph | Chief Scientific Officer | Dec 17, 2015 | Sale | $25.14 | 6,463 | 162,480 | 72,215 | Dec 17, 2015, 07:32 PM |
| Lengauer Christoph | Chief Scientific Officer | Dec 16, 2015 | Sale | $25.03 | 24,156 | 604,625 | 78,678 | Dec 17, 2015, 07:32 PM |
| Lengauer Christoph | Chief Scientific Officer | Dec 15, 2015 | Sale | $25.00 | 500 | 12,500 | 102,834 | Dec 17, 2015, 07:32 PM |
| FMR LLC | See Remark 1 | Nov 25, 2015 | Sale | $21.36 | 229,596 | 4,903,417 | 496,813 | Nov 30, 2015, 02:32 PM |
| FMR LLC | See Remark 1 | Nov 27, 2015 | Sale | $21.97 | 57,819 | 1,270,019 | 320,317 | Nov 30, 2015, 02:32 PM |
| FMR LLC | 10% Owner | Nov 24, 2015 | Sale | $20.14 | 161,271 | 3,247,998 | 552,313 | Nov 25, 2015, 10:49 AM |
| FMR LLC | 10% Owner | Nov 23, 2015 | Sale | $20.17 | 85,300 | 1,720,737 | 775,184 | Nov 23, 2015, 06:12 PM |
| FMR LLC | 10% Owner | Nov 20, 2015 | Sale | $20.14 | 104,272 | 2,099,716 | 880,156 | Nov 23, 2015, 06:12 PM |
| FMR LLC | 10% Owner | Nov 19, 2015 | Sale | $19.81 | 155,894 | 3,088,621 | 1,034,200 | Nov 20, 2015, 03:07 PM |
| FMR LLC | 10% Owner | Nov 18, 2015 | Sale | $19.67 | 81,324 | 1,599,864 | 1,135,174 | Nov 20, 2015, 03:07 PM |
| FMR LLC | 10% Owner | Nov 17, 2015 | Sale | $20.60 | 27,490 | 566,220 | 1,164,064 | Nov 19, 2015, 01:36 PM |
| FMR LLC | 10% Owner | Nov 16, 2015 | Sale | $20.83 | 28,684 | 597,544 | 1,173,496 | Nov 18, 2015, 11:29 AM |
| Albers Jeffrey W. | CEO and President | Nov 10, 2015 | Sale | $21.87 | 7,000 | 153,090 | 126,486 | Nov 12, 2015, 05:29 PM |
| Lengauer Christoph | Chief Scientific Officer | Nov 03, 2015 | Sale | $20.98 | 36,734 | 770,679 | 103,334 | Nov 04, 2015, 05:16 PM |
| Lengauer Christoph | Chief Scientific Officer | Nov 02, 2015 | Sale | $21.10 | 48,264 | 1,018,370 | 140,068 | Nov 04, 2015, 05:16 PM |
| Albers Jeffrey W. | CEO and President | Nov 02, 2015 | Sale | $21.02 | 10,000 | 210,200 | 133,486 | Nov 04, 2015, 05:14 PM |
| FMR LLC | 10% Owner | May 05, 2015 | Buy | $18.00 | 125,000 | 2,250,000 | 2,500,711 | May 07, 2015, 04:49 PM |
Load More Insider Transactions
Buy
Sale
Option Exercise
| Owner | Relationship | Date | Value($) |
| Albers Jeffrey W. | Director | 09/09/2024 | 360,500 |
| Albers Jeffrey W. | Director | 09/09/2024 | 1,685,891 |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | 08/15/2024 | 419,869 |
| Lee Philina | CHIEF COMMERCIAL OFFICER | 08/05/2024 | 2,828,921 |
| Lee Philina | CHIEF COMMERCIAL OFFICER | 08/05/2024 | 3,905,873 |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | 07/03/2024 | 477,264 |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | 07/05/2024 | 208,401 |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | 07/03/2024 | 981,244 |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | 07/05/2024 | 428,120 |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | 06/21/2024 | 2,085,501 |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | 06/21/2024 | 7,713,537 |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | 06/04/2024 | 254,302 |
| Carter Percy H. | CHIEF SCIENTIFIC OFFICER | 06/03/2024 | 259,263 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 05/15/2024 | 220,736 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 05/15/2024 | 626,379 |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | 05/08/2024 | 65,297 |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | 05/02/2024 | 360,500 |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | 05/02/2024 | 1,050,000 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 05/02/2024 | 99,274 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 05/02/2024 | 190,516 |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | 03/28/2024 | 180,250 |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | 03/28/2024 | 475,000 |
| Albers Jeffrey W. | Director | 03/07/2024 | 1,000,583 |
| Albers Jeffrey W. | Director | 03/20/2024 | 178,287 |
| Albers Jeffrey W. | Director | 03/20/2024 | 2,188,265 |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | 03/15/2024 | 180,250 |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | 03/15/2024 | 1,205,606 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 03/15/2024 | 24,016 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 03/15/2024 | 399,213 |
| Lee Philina | CHIEF COMMERCIAL OFFICER | 03/13/2024 | 22,975 |
| Lee Philina | CHIEF COMMERCIAL OFFICER | 03/13/2024 | 725,277 |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | 03/07/2024 | 280,867 |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | 03/07/2024 | 461,884 |
| Haviland Kate | CHIEF EXECUTIVE OFFICER | 03/07/2024 | 1,130,360 |
| Lee Philina | CHIEF COMMERCIAL OFFICER | 03/07/2024 | 266,084 |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | 03/07/2024 | 228,629 |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | 03/07/2024 | 453,722 |
| Rossi Christina | CHIEF OPERATING OFFICER | 03/07/2024 | 550,488 |
| Namouni Fouad | PRESIDENT, R & D | 03/07/2024 | 396,950 |
| Carter Percy H. | CHIEF SCIENTIFIC OFFICER | 03/07/2024 | 207,317 |
| McCain Tracey L | EVP AND CHIEF LEGAL OFFICER | 03/07/2024 | 471,044 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 03/07/2024 | 132,589 |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | 03/04/2024 | 58,157 |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | 02/28/2024 | 270,650 |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | 02/28/2024 | 500,000 |
| Lee Philina | CHIEF COMMERCIAL OFFICER | 12/13/2023 | 488 |
| Albers Jeffrey W. | Director | 01/25/2024 | 178,150 |
| Albers Jeffrey W. | Director | 01/25/2024 | 2,047,800 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 12/22/2023 | 6,283 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 12/22/2023 | 64,260 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 12/15/2023 | 6,833 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 12/15/2023 | 330,146 |
| Albers Jeffrey W. | Director | 12/11/2023 | 180,250 |
| Albers Jeffrey W. | Director | 12/11/2023 | 395,350 |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | 12/07/2023 | 270,650 |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | 12/07/2023 | 375,000 |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | 12/04/2023 | 42,858 |
| Albers Jeffrey W. | Director | 11/30/2023 | 180,250 |
| Albers Jeffrey W. | Director | 11/30/2023 | 352,750 |
| Albers Jeffrey W. | Director | 11/24/2023 | 28,050 |
| Albers Jeffrey W. | Director | 11/24/2023 | 1,012,690 |
| Albers Jeffrey W. | Director | 11/01/2023 | 139,910 |
| Albers Jeffrey W. | Director | 11/03/2023 | 53,534 |
| Albers Jeffrey W. | Director | 11/02/2023 | 167,056 |
| Albers Jeffrey W. | Director | 11/03/2023 | 89,293 |
| Albers Jeffrey W. | Director | 11/02/2023 | 279,749 |
| Albers Jeffrey W. | Director | 11/01/2023 | 232,938 |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | 10/26/2023 | 33,840 |
| Namouni Fouad | PRESIDENT, R & D | 10/04/2023 | 181,138 |
| Albers Jeffrey W. | Director | 09/27/2023 | 33,851 |
| Albers Jeffrey W. | Director | 09/28/2023 | 12,899 |
| Albers Jeffrey W. | Director | 09/28/2023 | 346,073 |
| Albers Jeffrey W. | Director | 09/27/2023 | 897,957 |
| Albers Jeffrey W. | Director | 08/25/2023 | 18,700 |
| Albers Jeffrey W. | Director | 08/24/2023 | 28,050 |
| Albers Jeffrey W. | Director | 08/25/2023 | 501,600 |
| Albers Jeffrey W. | Director | 08/24/2023 | 743,550 |
| Carter Percy H. | CHIEF SCIENTIFIC OFFICER | 06/05/2023 | 120,102 |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | 06/05/2023 | 73,078 |
| Murray Christopher K. | CHIEF TECHNICAL OPERATIONS | 03/06/2023 | 85,641 |
| Rossi Christina | CHIEF OPERATING OFFICER | 03/06/2023 | 139,715 |
| Namouni Fouad | PRESIDENT, R & D | 03/06/2023 | 88,977 |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | 03/06/2023 | 69,174 |
| Lee Philina | CHIEF COMMERCIAL OFFICER | 03/06/2023 | 76,555 |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | 03/06/2023 | 144,248 |
| Carter Percy H. | CHIEF SCIENTIFIC OFFICER | 03/06/2023 | 34,769 |
| Albers Jeffrey W. | Director | 03/06/2023 | 447,273 |
| McCain Tracey L | EVP AND CHIEF LEGAL OFFICER | 03/06/2023 | 151,743 |
| Landsittel Michael | CHIEF FINANCIAL OFFICER | 03/06/2023 | 137,361 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 03/06/2023 | 51,435 |
| Haviland Kate | CHIEF EXECUTIVE OFFICER | 03/06/2023 | 303,354 |
| Albers Jeffrey W. | Director | 12/05/2022 | 168,800 |
| Albers Jeffrey W. | Director | 12/05/2022 | 1,001,800 |
| Rossi Christina | CHIEF OPERATING OFFICER | 11/03/2022 | 24,113 |
| Haviland Kate | CHIEF EXECUTIVE OFFICER | 11/03/2022 | 48,378 |
| Namouni Fouad | PRESIDENT, R & D | 10/04/2022 | 234,002 |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | 08/24/2022 | 75,050 |
| Durso-Bumpus Debra | CHIEF PEOPLE OFFICER | 08/24/2022 | 375,550 |
| Albers Jeffrey W. | Director | 08/22/2022 | 126,234 |
| Albers Jeffrey W. | Director | 08/19/2022 | 23,866 |
| Albers Jeffrey W. | Director | 08/22/2022 | 593,202 |
| Albers Jeffrey W. | Director | 08/19/2022 | 111,332 |
| Albers Jeffrey W. | Director | 08/16/2022 | 168,800 |
| Albers Jeffrey W. | Director | 08/16/2022 | 1,368,253 |
| Albers Jeffrey W. | Director | 08/08/2022 | 68,388 |
| Albers Jeffrey W. | Director | 08/08/2022 | 700,700 |
| Murray Christopher K. | SVP, TECHNICAL OPERATIONS | 08/05/2022 | 162,500 |
| Murray Christopher K. | SVP, TECHNICAL OPERATIONS | 08/04/2022 | 151,100 |
| Demetri George | Director | 07/13/2021 | 827 |
| Demetri George | Director | 03/17/2022 | 586 |
| Carter Percy H. | CHIEF SCIENTIFIC OFFICER | 06/06/2022 | 114,022 |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | 06/07/2022 | 189,300 |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | 06/06/2022 | 72,907 |
| Lydon Nicholas | Director | 05/23/2022 | 213,053 |
| Albers Jeffrey W. | Director | 05/16/2022 | 168,800 |
| Albers Jeffrey W. | Director | 05/16/2022 | 1,117,815 |
| Albers Jeffrey W. | CEO AND PRESIDENT | 04/06/2022 | 75,050 |
| Albers Jeffrey W. | CEO AND PRESIDENT | 04/06/2022 | 350,550 |
| Rossi Christina | CHIEF COMMERCIAL OFFICER | 11/03/2021 | 56,644 |
| Hewes L. Becker | CHIEF MEDICAL OFFICER | 03/16/2022 | 133,140 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 03/10/2022 | 133,674 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 03/07/2022 | 14,385 |
| Hurley Ariel | PRINCIPAL ACCOUNTING OFFICER | 03/03/2022 | 45,865 |
| Albers Jeffrey W. | CEO AND PRESIDENT | 03/04/2022 | 201,650 |
| Albers Jeffrey W. | CEO AND PRESIDENT | 03/07/2022 | 272,128 |
| Albers Jeffrey W. | CEO AND PRESIDENT | 03/04/2022 | 1,147,662 |
| Albers Jeffrey W. | CEO AND PRESIDENT | 03/03/2022 | 473,921 |
| Namouni Fouad | PRESIDENT, R & D | 03/07/2022 | 58,831 |
| Rossi Christina | CHIEF COMMERCIAL OFFICER | 03/07/2022 | 58,831 |
| Rossi Christina | CHIEF COMMERCIAL OFFICER | 03/03/2022 | 72,155 |
| Goldberg Mark Alan | Director | 03/03/2022 | 299,900 |
| Hewes L. Becker | Chief Medical Officer | 12/15/2021 | 48,289 |
| Hewes L. Becker | Chief Medical Officer | 12/15/2021 | 72,900 |
| Haviland Kate | Chief Operating Officer | 12/13/2021 | 36,050 |
| Haviland Kate | Chief Operating Officer | 12/13/2021 | 98,296 |
| McCain Tracey L | EVP and Chief Legal Officer | 12/07/2021 | 141,800 |
| McCain Tracey L | EVP and Chief Legal Officer | 12/07/2021 | 486,490 |
| Hurley Ariel | Principal Accounting Officer | 11/16/2021 | 16,035 |
| Hurley Ariel | Principal Accounting Officer | 11/16/2021 | 222,846 |
| Albers Jeffrey W. | CEO and President | 11/15/2021 | 351,750 |
| Albers Jeffrey W. | CEO and President | 11/15/2021 | 3,435,099 |
| Hewes L. Becker | Chief Medical Officer | 11/15/2021 | 48,289 |
| Hewes L. Becker | Chief Medical Officer | 11/15/2021 | 84,192 |
| McCain Tracey L | EVP and Chief Legal Officer | 11/03/2021 | 141,800 |
| McCain Tracey L | EVP and Chief Legal Officer | 11/03/2021 | 552,812 |
| Durso-Bumpus Debra | Chief People Officer | 11/01/2021 | 151,885 |
| Durso-Bumpus Debra | Chief People Officer | 11/01/2021 | 585,172 |
| Albers Jeffrey W. | CEO and President | 11/01/2021 | 75,050 |
| Albers Jeffrey W. | CEO and President | 11/01/2021 | 575,800 |
| Hewes L. Becker | Chief Medical Officer | 10/15/2021 | 48,289 |
| Hewes L. Becker | Chief Medical Officer | 10/15/2021 | 74,839 |
| Namouni Fouad | President, R & D | 10/05/2021 | 318,201 |
| Hurley Ariel | Principal Accounting Officer | 09/23/2021 | 9,006 |
| Hurley Ariel | Principal Accounting Officer | 09/23/2021 | 66,000 |
| McCain Tracey L | EVP and Chief Legal Officer | 09/23/2021 | 709,000 |
| McCain Tracey L | EVP and Chief Legal Officer | 09/23/2021 | 2,721,349 |
| Durso-Bumpus Debra | Chief People Officer | 09/23/2021 | 30,570 |
| Durso-Bumpus Debra | Chief People Officer | 09/23/2021 | 93,288 |
| Hewes L. Becker | Chief Medical Officer | 09/15/2021 | 579,600 |
| Hewes L. Becker | Chief Medical Officer | 09/15/2021 | 1,197,139 |
| Hewes L. Becker | Chief Medical Officer | 06/02/2021 | 115,027 |
| Hurley Ariel | Principal Accounting Officer | 09/13/2021 | 9,006 |
| Hurley Ariel | Principal Accounting Officer | 09/13/2021 | 60,000 |
| Haviland Kate | Chief Operating Officer | 09/13/2021 | 36,050 |
| Haviland Kate | Chief Operating Officer | 09/13/2021 | 99,936 |
| Albers Jeffrey W. | CEO and President | 08/26/2021 | 29,920 |
| Albers Jeffrey W. | CEO and President | 08/19/2021 | 276,700 |
| Albers Jeffrey W. | CEO and President | 08/19/2021 | 2,317,102 |
| Hurley Ariel | Principal Accounting Officer | 08/17/2021 | 7,029 |
| Hurley Ariel | Principal Accounting Officer | 08/17/2021 | 124,106 |
| Haviland Kate | Chief Operating Officer | 06/28/2021 | 36,050 |
| Haviland Kate | Chief Operating Officer | 06/28/2021 | 90,238 |
| Albers Jeffrey W. | CEO and President | 05/12/2021 | 276,700 |
| Albers Jeffrey W. | CEO and President | 05/12/2021 | 2,317,366 |
| Hurley Ariel | Principal Accounting Officer | 03/03/2021 | 50,406 |
| Haviland Kate | Chief Operating Officer | 03/15/2021 | 36,050 |
| Haviland Kate | Chief Operating Officer | 03/15/2021 | 105,603 |
| Durso-Bumpus Debra | Chief People Officer | 03/04/2021 | 146,887 |
| Hurley Ariel | Principal Accounting Officer | 03/04/2021 | 74,364 |
| Hurley Ariel | Principal Accounting Officer | 03/03/2021 | 50,702 |
| Haviland Kate | Chief Operating Officer | 03/04/2021 | 169,370 |
| Landsittel Michael | Chief Financial Officer | 03/04/2021 | 130,749 |
| McCain Tracey L | EVP and Chief Legal Officer | 03/04/2021 | 164,242 |
| Murray Christopher K. | SVP, Technical Operations | 03/04/2021 | 104,984 |
| Rossi Christina | Chief Commercial Officer | 03/04/2021 | 117,920 |
| Albers Jeffrey W. | CEO and President | 03/04/2021 | 88,000 |
| Albers Jeffrey W. | CEO and President | 03/04/2021 | 1,695,006 |
| Hurley Ariel | Principal Accounting Officer | 03/01/2021 | 5,258 |
| Hurley Ariel | Principal Accounting Officer | 03/01/2021 | 169,167 |
| Dorsch Marion | Chief Scientific Officer | 02/22/2021 | 281,220 |
| Dorsch Marion | Chief Scientific Officer | 02/22/2021 | 757,800 |
| Demetri George | Director | 01/04/2021 | 85,010 |
| Goldberg Mark Alan | Director | 12/24/2020 | 153,558 |
| Goldberg Mark Alan | Director | 12/24/2020 | 681,875 |
| Goldberg Mark Alan | Director | 12/18/2020 | 153,530 |
| Goldberg Mark Alan | Director | 12/18/2020 | 654,480 |
| Rowland Charles A Jr | Director | 12/17/2020 | 213,053 |
| Rowland Charles A Jr | Director | 12/17/2020 | 1,285,298 |
| Albers Jeffrey W. | CEO and President | 12/14/2020 | 44,000 |
| Albers Jeffrey W. | CEO and President | 12/14/2020 | 595,900 |
| Boral Anthony L. | Chief Medical Officer | 12/14/2020 | 150,100 |
| Boral Anthony L. | Chief Medical Officer | 12/14/2020 | 1,185,200 |
| Dorsch Marion | Chief Scientific Officer | 12/14/2020 | 170,706 |
| Dorsch Marion | Chief Scientific Officer | 12/14/2020 | 547,400 |
| Goldberg Mark Alan | Director | 12/11/2020 | 153,558 |
| Goldberg Mark Alan | Director | 12/11/2020 | 627,325 |
| Goldberg Mark Alan | Director | 12/01/2020 | 153,530 |
| Goldberg Mark Alan | Director | 12/01/2020 | 599,940 |
| Hurley Ariel | Principal Accounting Officer | 12/01/2020 | 7,920 |
| Hurley Ariel | Principal Accounting Officer | 12/01/2020 | 114,053 |
| Haviland Kate | Chief Operating Officer | 11/16/2020 | 14,744 |
| Haviland Kate | Chief Operating Officer | 11/16/2020 | 41,010 |
| Albers Jeffrey W. | CEO and President | 11/16/2020 | 176,000 |
| Albers Jeffrey W. | CEO and President | 11/16/2020 | 1,974,295 |
| Hurley Ariel | Principal Accounting Officer | 11/16/2020 | 5,258 |
| Hurley Ariel | Principal Accounting Officer | 11/16/2020 | 171,564 |
| Rossi Christina | Chief Commercial Officer | 11/03/2020 | 34,393 |
| Rowland Charles A Jr | Director | 11/03/2020 | 52,238 |
| Rowland Charles A Jr | Director | 11/02/2020 | 42,362 |
| Rowland Charles A Jr | Director | 11/03/2020 | 545,196 |
| Rowland Charles A Jr | Director | 11/02/2020 | 443,815 |
| Boral Anthony L. | Chief Medical Officer | 10/23/2020 | 116,667 |
| Goldberg Mark Alan | Director | 10/19/2020 | 106,536 |
| Goldberg Mark Alan | Director | 10/19/2020 | 572,775 |
| Haviland Kate | Chief Operating Officer | 10/16/2020 | 480,691 |
| Haviland Kate | Chief Operating Officer | 10/16/2020 | 1,349,848 |
| Hurley Ariel | Principal Accounting Officer | 10/07/2020 | 5,280 |
| Hurley Ariel | Principal Accounting Officer | 10/07/2020 | 60,000 |
| Albers Jeffrey W. | CEO and President | 10/07/2020 | 44,000 |
| Albers Jeffrey W. | CEO and President | 10/07/2020 | 495,850 |
| Goldberg Mark Alan | Director | 10/07/2020 | 106,517 |
| Goldberg Mark Alan | Director | 10/07/2020 | 545,400 |
| Dorsch Marion | Chief Scientific Officer | 10/06/2020 | 170,706 |
| Dorsch Marion | Chief Scientific Officer | 10/06/2020 | 455,400 |
| Lydon Nicholas | Director | 10/01/2020 | 913,595 |
| Dorsch Marion | Chief Scientific Officer | 09/23/2020 | 170,706 |
| Dorsch Marion | Chief Scientific Officer | 09/23/2020 | 409,400 |
| Hurley Ariel | Principal Accounting Officer | 09/23/2020 | 2,618 |
| Hurley Ariel | Principal Accounting Officer | 09/23/2020 | 126,000 |
| Durso-Bumpus Debra | Chief People Officer | 09/23/2020 | 68,495 |
| Durso-Bumpus Debra | Chief People Officer | 09/23/2020 | 171,038 |
| Demetri George | Director | 09/22/2020 | 144,840 |
| Boral Anthony L. | Chief Medical Officer | 09/22/2020 | 103,029 |
| Boral Anthony L. | Chief Medical Officer | 09/22/2020 | 565,113 |
| Haviland Kate | Chief Operating Officer | 09/22/2020 | 51,168 |
| Haviland Kate | Chief Operating Officer | 09/22/2020 | 268,695 |
| Boral Anthony L. | Chief Medical Officer | 09/17/2020 | 264,945 |
| Boral Anthony L. | Chief Medical Officer | 09/17/2020 | 1,850,880 |
| Lydon Nicholas | Director | 09/17/2020 | 40,000 |
| Albers Jeffrey W. | CEO and President | 08/19/2020 | 176,000 |
| Albers Jeffrey W. | CEO and President | 08/19/2020 | 1,500,438 |
| Hurley Ariel | Principal Accounting Officer | 08/17/2020 | 1,309 |
| Hurley Ariel | Principal Accounting Officer | 08/17/2020 | 52,500 |
| Lydon Nicholas | Director | 07/06/2020 | 2,092,351 |
| Lydon Nicholas | Director | 07/02/2020 | 226,367 |
| Lydon Nicholas | Director | 07/01/2020 | 104,273 |
| Lydon Nicholas | Director | 06/23/2020 | 32,000 |
| Durso-Bumpus Debra | Chief People Officer | 06/22/2020 | 82,915 |
| Durso-Bumpus Debra | Chief People Officer | 06/22/2020 | 184,161 |
| Lydon Nicholas | Director | 06/22/2020 | 1,045,135 |
| Dorsch Marion | Chief Scientific Officer | 06/19/2020 | 170,706 |
| Dorsch Marion | Chief Scientific Officer | 06/19/2020 | 363,400 |
| Durso-Bumpus Debra | Chief People Officer | 06/18/2020 | 45,000 |
| Durso-Bumpus Debra | Chief People Officer | 06/18/2020 | 187,950 |
| Hurley Ariel | Principal Accounting Officer | 06/09/2020 | 1,309 |
| Hurley Ariel | Principal Accounting Officer | 06/09/2020 | 52,500 |
| Hurley Ariel | Principal Accounting Officer | 06/02/2020 | 15,517 |
| Albers Jeffrey W. | CEO and President | 05/12/2020 | 176,000 |
| Albers Jeffrey W. | CEO and President | 05/12/2020 | 1,293,427 |
| Dorsch Marion | Chief Scientific Officer | 03/23/2020 | 63,726 |
| Albers Jeffrey W. | CEO and President | 03/23/2020 | 212,846 |
| Albers Jeffrey W. | CEO and President | 03/23/2020 | 1,041,922 |
| Hurley Ariel | Principal Accounting Officer | 03/09/2020 | 13,141 |
| Albers Jeffrey W. | CEO and President | 03/09/2020 | 118,336 |
| Boral Anthony L. | Chief Medical Officer | 03/09/2020 | 27,856 |
| Dorsch Marion | Chief Scientific Officer | 03/09/2020 | 27,867 |
| Durso-Bumpus Debra | Chief People Officer | 03/09/2020 | 22,438 |
| Haviland Kate | Chief Operating Officer | 03/09/2020 | 34,879 |
| Landsittel Michael | Chief Financial Officer | 03/09/2020 | 20,788 |
| McCain Tracey L | EVP and Chief Legal Officer | 03/09/2020 | 32,072 |
| Murray Christopher K. | SVP, Technical Operations | 03/09/2020 | 20,880 |
| Rossi Christina | Chief Commercial Officer | 03/09/2020 | 7,015 |
| Haviland Kate | Chief Operating Officer | 03/03/2020 | 75,604 |
| Demetri George | Director | 01/10/2020 | 48,280 |
| Haviland Kate | Chief Operating Officer | 01/10/2020 | 126,382 |
| Haviland Kate | Chief Operating Officer | 01/10/2020 | 661,097 |
| Demetri George | Director | 01/07/2020 | 137,406 |
| Dorsch Marion | Chief Scientific Officer | 12/19/2019 | 170,706 |
| Dorsch Marion | Chief Scientific Officer | 12/19/2019 | 363,400 |
| Boral Anthony L. | Chief Medical Officer | 12/17/2019 | 88,000 |
| Boral Anthony L. | Chief Medical Officer | 12/17/2019 | 765,713 |
| Hurley Ariel | Principal Accounting Officer | 12/16/2019 | 776 |
| Hurley Ariel | Principal Accounting Officer | 12/16/2019 | 31,125 |
| Hurley Ariel | Principal Accounting Officer | 12/04/2019 | 14,832 |
| Albers Jeffrey W. | CEO and President | 11/18/2019 | 51,260 |
| Albers Jeffrey W. | CEO and President | 11/08/2019 | 875,633 |
| Albers Jeffrey W. | CEO and President | 11/18/2019 | 622,652 |
| Hurley Ariel | Principal Accounting Officer | 11/15/2019 | 776 |
| Hurley Ariel | Principal Accounting Officer | 11/15/2019 | 31,125 |
| Albers Jeffrey W. | CEO and President | 10/30/2019 | 37,400 |
| Hurley Ariel | Principal Accounting Officer | 10/17/2019 | 776 |
| Hurley Ariel | Principal Accounting Officer | 10/17/2019 | 31,125 |
| Hurley Ariel | Principal Accounting Officer | 09/16/2019 | 776 |
| Hurley Ariel | Principal Accounting Officer | 09/16/2019 | 32,428 |
| Boral Anthony L. | Chief Medical Officer | 08/20/2019 | 11,440 |
| Boral Anthony L. | Chief Medical Officer | 08/21/2019 | 76,560 |
| Boral Anthony L. | Chief Medical Officer | 08/20/2019 | 104,572 |
| Boral Anthony L. | Chief Medical Officer | 08/21/2019 | 696,087 |
| Haviland Kate | Chief Operating Officer | 08/19/2019 | 1,547 |
| Haviland Kate | Chief Operating Officer | 08/19/2019 | 8,075 |
| Albers Jeffrey W. | CEO and President | 08/19/2019 | 37,400 |
| Albers Jeffrey W. | CEO and President | 08/19/2019 | 1,634,661 |
| Hurley Ariel | Principal Accounting Officer | 08/15/2019 | 776 |
| Hurley Ariel | Principal Accounting Officer | 08/15/2019 | 34,868 |
| COATS LONNEL | Director | 08/15/2019 | 150,100 |
| COATS LONNEL | Director | 08/15/2019 | 824,007 |
| Hurley Ariel | Principal Accounting Officer | 07/19/2019 | 1,012 |
| Hurley Ariel | Principal Accounting Officer | 07/19/2019 | 11,500 |
| Haviland Kate | Chief Operating Officer | 07/16/2019 | 188,229 |
| Haviland Kate | Chief Operating Officer | 07/16/2019 | 149,989 |
| Hurley Ariel | Principal Accounting Officer | 07/15/2019 | 1,552 |
| Hurley Ariel | Principal Accounting Officer | 07/15/2019 | 78,833 |
| Boral Anthony L. | Chief Medical Officer | 07/08/2019 | 88,000 |
| Boral Anthony L. | Chief Medical Officer | 07/08/2019 | 938,756 |
| Borisy Alexis | Director | 06/27/2019 | 715,085 |
| Borisy Alexis | Director | 06/27/2019 | 2,007,446 |
| Rowland Charles A Jr | Director | 06/20/2019 | 111,798 |
| Rowland Charles A Jr | Director | 06/20/2019 | 1,124,462 |
| Dorsch Marion | Chief Scientific Officer | 06/17/2019 | 170,706 |
| Dorsch Marion | Chief Scientific Officer | 06/17/2019 | 455,400 |
| Haviland Kate | Chief Operating Officer | 06/17/2019 | 306,595 |
| Haviland Kate | Chief Operating Officer | 06/17/2019 | 1,152,870 |
| Albers Jeffrey W. | CEO and President | 06/17/2019 | 9,350 |
| Albers Jeffrey W. | CEO and President | 06/17/2019 | 495,300 |
| Demetri George | Director | 06/17/2019 | 111,890 |
| Hurley Ariel | Principal Accounting Officer | 06/17/2019 | 6,612 |
| Hurley Ariel | Principal Accounting Officer | 06/17/2019 | 138,002 |
| Demetri George | Director | 06/13/2019 | 51,120 |
| Lydon Nicholas | Director | 06/13/2019 | 2,259,000 |
| Hurley Ariel | Principal Accounting Officer | 06/13/2019 | 3,104 |
| Hurley Ariel | Principal Accounting Officer | 06/12/2019 | 1,552 |
| Hurley Ariel | Principal Accounting Officer | 06/12/2019 | 91,205 |
| Hurley Ariel | Principal Accounting Officer | 06/13/2019 | 149,400 |
| Lydon Nicholas | Director | 06/12/2019 | 2,119,162 |
| Albers Jeffrey W. | CEO and President | 06/12/2019 | 37,400 |
| Albers Jeffrey W. | CEO and President | 06/12/2019 | 1,694,906 |
| Albers Jeffrey W. | CEO and President | 03/15/2019 | 37,400 |
| Albers Jeffrey W. | CEO and President | 03/15/2019 | 1,727,884 |
| Hurley Ariel | Principal Accounting Officer | 03/15/2019 | 776 |
| Hurley Ariel | Principal Accounting Officer | 03/15/2019 | 35,503 |
| Dorsch Marion | Chief Scientific Officer | 03/04/2019 | 85,353 |
| Dorsch Marion | Chief Scientific Officer | 03/04/2019 | 194,723 |
| Haviland Kate | Chief Operating Officer | 03/01/2019 | 500,639 |
| Haviland Kate | Chief Operating Officer | 03/01/2019 | 1,840,822 |
| Albers Jeffrey W. | CEO and President | 11/19/2018 | 54,157 |
| Albers Jeffrey W. | CEO and President | 11/05/2018 | 37,400 |
| Albers Jeffrey W. | CEO and President | 11/05/2018 | 1,269,709 |
| Dorsch Marion | Chief Scientific Officer | 09/17/2018 | 85,353 |
| Dorsch Marion | Chief Scientific Officer | 09/17/2018 | 162,092 |
| Albers Jeffrey W. | CEO and President | 08/06/2018 | 37,400 |
| Albers Jeffrey W. | CEO and President | 08/06/2018 | 1,411,897 |
| Albers Jeffrey W. | CEO and President | 05/07/2018 | 37,400 |
| Albers Jeffrey W. | CEO and President | 05/07/2018 | 1,578,091 |
| Demetri George | Director | 03/19/2018 | 549,672 |
| Haviland Kate | Chief Business Officer | 03/16/2018 | 115,701 |
| Haviland Kate | Chief Business Officer | 03/16/2018 | 410,138 |
| Dorsch Marion | Chief Scientific Officer | 03/15/2018 | 85,353 |
| Dorsch Marion | Chief Scientific Officer | 03/15/2018 | 230,161 |
| Albers Jeffrey W. | CEO and President | 03/02/2018 | 37,400 |
| Albers Jeffrey W. | CEO and President | 03/02/2018 | 1,851,463 |
| Haviland Kate | Chief Business Officer | 03/01/2018 | 100,940 |
| Haviland Kate | Chief Business Officer | 03/01/2018 | 252,000 |
| Lydon Nicholas | Director | 02/28/2018 | 2,197,356 |
| Haviland Kate | Chief Business Officer | 02/27/2018 | 115,360 |
| Haviland Kate | Chief Business Officer | 02/27/2018 | 282,236 |
| McCain Tracey L | EVP and Chief Legal Officer | 02/27/2018 | 283,600 |
| McCain Tracey L | EVP and Chief Legal Officer | 02/27/2018 | 883,450 |
| Demetri George | Director | 02/27/2018 | 551,805 |
| LYNCH DANIEL | Director | 02/14/2018 | 1,005,250 |
| LYNCH DANIEL | Director | 02/12/2018 | 1,309,668 |
| Haviland Kate | Chief Business Officer | 02/12/2018 | 110,297 |
| Haviland Kate | Chief Business Officer | 02/12/2018 | 507,619 |
| Dorsch Marion | Chief Scientific Officer | 11/22/2017 | 340,150 |
| Dorsch Marion | Chief Scientific Officer | 11/22/2017 | 641,620 |
| Dorsch Marion | Chief Scientific Officer | 11/21/2017 | 32,220 |
| Dorsch Marion | Chief Scientific Officer | 11/21/2017 | 680,375 |
| Dorsch Marion | Chief Scientific Officer | 11/21/2017 | 1,200,013 |
| Haviland Kate | Chief Business Officer | 11/21/2017 | 95,629 |
| LYNCH DANIEL | Director | 11/15/2017 | 316,898 |
| Boral Anthony L. | Chief Medical Officer | 11/06/2017 | 44,000 |
| Boral Anthony L. | Chief Medical Officer | 11/06/2017 | 352,022 |
| Albers Jeffrey W. | CEO and President | 11/06/2017 | 45,841 |
| Albers Jeffrey W. | CEO and President | 11/06/2017 | 2,109,251 |
| Haviland Kate | Chief Business Officer | 10/05/2017 | 88,710 |
| Haviland Kate | Chief Business Officer | 10/05/2017 | 362,033 |
| Haviland Kate | Chief Business Officer | 09/18/2017 | 103,476 |
| Haviland Kate | Chief Business Officer | 09/18/2017 | 381,551 |
| LYNCH DANIEL | Director | 09/18/2017 | 150,000 |
| Boral Anthony L. | Chief Medical Officer | 08/09/2017 | 44,000 |
| Boral Anthony L. | Chief Medical Officer | 08/09/2017 | 242,986 |
| Albers Jeffrey W. | CEO and President | 08/08/2017 | 507,000 |
| Albers Jeffrey W. | CEO and President | 08/07/2017 | 981,637 |
| LYNCH DANIEL | Director | 07/05/2017 | 412,950 |
| Haviland Kate | Chief Business Officer | 07/05/2017 | 118,274 |
| Haviland Kate | Chief Business Officer | 07/05/2017 | 397,077 |
| Boral Anthony L. | Chief Medical Officer | 06/28/2017 | 88,000 |
| Boral Anthony L. | Chief Medical Officer | 06/28/2017 | 504,750 |
| LYNCH DANIEL | Director | 06/28/2017 | 1,633,977 |
| Albers Jeffrey W. | CEO and President | 06/28/2017 | 1,009,394 |
| Haviland Kate | Chief Business Officer | 06/28/2017 | 103,492 |
| Haviland Kate | Chief Business Officer | 06/28/2017 | 317,850 |
| Haviland Kate | Chief Business Officer | 03/14/2017 | 206,984 |
| Haviland Kate | Chief Business Officer | 03/14/2017 | 508,687 |
| LEVIN MARK J | 10% Owner | 03/16/2017 | 1,226,412 |
| Lydon Nicholas | Director | 03/14/2017 | 2,803,724 |
| Haviland Kate | Chief Business Officer | 03/14/2017 | 206,984 |
| Haviland Kate | Chief Business Officer | 03/14/2017 | 508,687 |
| Albers Jeffrey W. | CEO and President | 03/14/2017 | 800,516 |
| LYNCH DANIEL | Director | 03/14/2017 | 300,900 |
| Third Rock Ventures II, L.P. | 10% Owner | 02/07/2017 | 35,275,002 |
| STARR KEVIN P | 10% Owner | 12/19/2016 | 3,002,351 |
| LYNCH DANIEL | Director | 12/01/2016 | 6,004 |
| LYNCH DANIEL | Director | 11/01/2016 | 51,068 |
| LYNCH DANIEL | Director | 10/13/2016 | 654,436 |
| Albers Jeffrey W. | CEO and President | 08/08/2016 | 388,663 |
| Albers Jeffrey W. | CEO and President | 06/03/2016 | 340,510 |
| Lengauer Christoph | Chief Scientific Officer | 04/13/2016 | 317,599 |
| Lengauer Christoph | Chief Scientific Officer | 04/12/2016 | 206,423 |
| Lengauer Christoph | Chief Scientific Officer | 04/11/2016 | 173,301 |
| Albers Jeffrey W. | CEO and President | 04/06/2016 | 347,140 |
| Lengauer Christoph | Chief Scientific Officer | 03/24/2016 | 31,030 |
| Lengauer Christoph | Chief Scientific Officer | 12/17/2015 | 162,480 |
| Lengauer Christoph | Chief Scientific Officer | 12/16/2015 | 604,625 |
| Lengauer Christoph | Chief Scientific Officer | 12/15/2015 | 12,500 |
| FMR LLC | See Remark 1 | 11/25/2015 | 4,903,417 |
| FMR LLC | See Remark 1 | 11/27/2015 | 1,270,019 |
| FMR LLC | 10% Owner | 11/24/2015 | 3,247,998 |
| FMR LLC | 10% Owner | 11/23/2015 | 1,720,737 |
| FMR LLC | 10% Owner | 11/20/2015 | 2,099,716 |
| FMR LLC | 10% Owner | 11/19/2015 | 3,088,621 |
| FMR LLC | 10% Owner | 11/18/2015 | 1,599,864 |
| FMR LLC | 10% Owner | 11/17/2015 | 566,220 |
| FMR LLC | 10% Owner | 11/16/2015 | 597,544 |
| Albers Jeffrey W. | CEO and President | 11/10/2015 | 153,090 |
| Lengauer Christoph | Chief Scientific Officer | 11/03/2015 | 770,679 |
| Lengauer Christoph | Chief Scientific Officer | 11/02/2015 | 1,018,370 |
| Albers Jeffrey W. | CEO and President | 11/02/2015 | 210,200 |
| FMR LLC | 10% Owner | 05/05/2015 | 2,250,000 |
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FUNDS WITH A POSITION IN BLUEPRINT MEDICINES CORPORATION
| Fund | # Shares Owned | % of Portfolio | % Change | Investing Style |
|---|---|---|---|---|
| BLACKROCK INC. | 6,647,297 | 0.02% | 3.1% | Other |
| GEODE CAPITAL MANAGEMENT, LLC | 1,459,484 | 0.01% | 6.44% | Other |
| HOLOCENE ADVISORS, LP | 943,464 | 0.42% | 31.9% | Growth At A Reasonable Price |
| D. E. SHAW & CO., INC. | 302,635 | 0.03% | -19.55% | Other |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 358,255 | 0.37% | 101.03% | Growth |
| FISHER ASSET MANAGEMENT, LLC | 336,165 | 0.02% | 0.31% | Other |
| RENAISSANCE TECHNOLOGIES LLC | 110,400 | 0.02% | 132.42% | Other |
| AQR CAPITAL MANAGEMENT LLC | 78,103 | 0.01% | 30.16% | Other |
| CANDRIAM S.C.A. | 52,066 | 0.03% | 29.95% | Other |
| OCONNOR, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS (LLC) | 20,000 (Put) | 0.00317% | New | Value |
| OCONNOR, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS (LLC) | 16,343 | 0.11% | -9.21% | Value |
| D. E. SHAW & CO., INC. | 10,600 (Put) | 0.00107% | 45.21% | Other |
| D. E. SHAW & CO., INC. | 10,000 (Call) | 0.00101% | New | Other |
| PLATINUM INVESTMENT MANAGEMENT LTD | 5,018 | 0.02% | Exited | Growth At A Reasonable Price, Value |
| FARALLON CAPITAL MANAGEMENT LLC | 4,000 | 0.00203% | No change | Event Driven, Value |
| TUDOR INVESTMENT CORP ET AL | 3,700 (Put) | 0.00204% | New | Event Driven, Other |
CHANGE IN SHARES OUTSTANDING FOR BLUEPRINT MEDICINES CORPORATION
STOCK BUYBACKS FOR BLUEPRINT MEDICINES CORPORATION
Period of Report
Previous Period
% Change in Shares
10-K/10-Q Filings
Quarter
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Period of Report: 06/30/2024
10-K/10-Q Filings: View
Previous Period
% Change in Shares
Quarter
03/31/2024
-1.49%
1Q
12/31/2023
3.21%
2Q
09/30/2023
3.57%
3Q
06/30/2023
3.86%
4Q
03/31/2023
4.54%
5Q
12/31/2022
4.97%
6Q
09/30/2022
5.18%
7Q
06/30/2022
5.43%
8Q
03/31/2022
5.97%
9Q
12/31/2021
6.55%
10Q
09/30/2021
7.17%
11Q
06/30/2021
7.62%
12Q
03/31/2021
8.33%
13Q
12/31/2020
8.00%
14Q
09/30/2020
10.69%
15Q
06/30/2020
15.93%
16Q
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BUYBACK ANNOUNCEMENT(S) FOR BLUEPRINT MEDICINES CORPORATION
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