| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| XLO | 10% Owner | Oct 26, 2021 | Buy | $16.00 | 500,000 | 8,000,000 | 1,256,472 | Oct 26, 2021, 05:04 PM |
| THRX | 10% Owner | Oct 12, 2021 | Buy | $16.00 | 250,000 | 4,000,000 | 599,320 | Oct 14, 2021, 05:00 PM |
| VERV | 10% Owner | Jun 21, 2021 | Buy | $19.00 | 370,000 | 7,030,000 | 926,298 | Jun 22, 2021, 05:20 PM |
| AVIR | 10% Owner | Nov 03, 2020 | Buy | $24.00 | 250,000 | 6,000,000 | 1,654,724 | Nov 04, 2020, 04:05 PM |
| INZY | 10% Owner | Jul 28, 2020 | Buy | $16.00 | 600,000 | 9,600,000 | 1,067,884 | Jul 28, 2020, 08:53 PM |
| IMRA | 10% Owner | Mar 16, 2020 | Buy | $16.00 | 250,000 | 4,000,000 | 523,411 | Mar 16, 2020, 05:04 PM |
| FIXX | 10% Owner | Apr 02, 2018 | Buy | $16.00 | 250,000 | 4,000,000 | 645,845 | Apr 04, 2018, 04:24 PM |
| NVLS | 10% Owner | Jun 22, 2015 | Buy | $14.00 | 200,000 | 2,800,000 | 564,358 | Jun 24, 2015, 04:09 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| XLO | 10% Owner | Oct 26, 2021 | Buy | 8,000,000 |
| THRX | 10% Owner | Oct 12, 2021 | Buy | 4,000,000 |
| VERV | 10% Owner | Jun 21, 2021 | Buy | 7,030,000 |
| AVIR | 10% Owner | Nov 03, 2020 | Buy | 6,000,000 |
| INZY | 10% Owner | Jul 28, 2020 | Buy | 9,600,000 |
| IMRA | 10% Owner | Mar 16, 2020 | Buy | 4,000,000 |
| FIXX | 10% Owner | Apr 02, 2018 | Buy | 4,000,000 |
| NVLS | 10% Owner | Jun 22, 2015 | Buy | 2,800,000 |