| Symbol | Company | Owner | Relationship | Date | Transaction | Cost | # Shares | Value ($) | Total Shares | Filing | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Feb 02, 2024 | Sale | $49.67 | 1,961 | 97,410 | 48,661 | Feb 02, 2024, 07:55 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Jan 25, 2024 | Sale | $51.75 | 6,450 | 333,788 | 46,802 | Jan 29, 2024, 05:34 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Jan 17, 2024 | Sale | $50.42 | 7,744 | 390,429 | 53,252 | Jan 18, 2024, 05:59 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Dec 26, 2023 | Option Exercise | $47.34 | 20,825 | 985,856 | 61,180 | Dec 28, 2023, 07:18 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Dec 26, 2023 | Sale | $51.46 | 20,825 | 1,071,717 | 40,355 | Dec 28, 2023, 07:18 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | May 24, 2023 | Sale | $41.70 | 1,527 | 63,676 | 40,355 | May 24, 2023, 08:25 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Feb 28, 2023 | Option Exercise | $30.51 | 301 | 9,185 | 41,882 | Mar 02, 2023, 05:19 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Feb 06, 2023 | Sale | $40.86 | 1,920 | 78,460 | 41,581 | Feb 07, 2023, 05:37 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Jan 30, 2023 | Sale | $39.42 | 4,500 | 177,372 | 44,179 | Feb 02, 2023, 01:48 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Jan 31, 2023 | Sale | $39.71 | 4,500 | 178,700 | 39,679 | Feb 02, 2023, 01:48 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Jan 18, 2023 | Sale | $39.49 | 7,836 | 309,480 | 48,679 | Jan 19, 2023, 08:21 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Aug 31, 2022 | Option Exercise | $28.97 | 108 | 3,129 | 34,644 | Sep 01, 2022, 07:03 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Apr 12, 2022 | Sale | $40.06 | 6,792 | 272,057 | 34,536 | Apr 14, 2022, 06:02 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Feb 28, 2022 | Option Exercise | $28.37 | 735 | 20,854 | 41,328 | Mar 02, 2022, 06:42 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP CLO & General Counsel | Jan 18, 2022 | Option Exercise | $30.12 | 7,501 | 225,930 | 40,593 | Jan 20, 2022, 08:18 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP Legal & General Counsel | Aug 31, 2021 | Option Exercise | $33.80 | 309 | 10,443 | 27,008 | Sep 02, 2021, 07:21 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP & General Counsel | Feb 26, 2021 | Option Exercise | $44.54 | 197 | 8,774 | 26,699 | Mar 02, 2021, 08:34 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP & General Counsel | Jan 25, 2021 | Sale | $63.50 | 5,324 | 338,074 | 26,502 | Jan 27, 2021, 05:35 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP & General Counsel | Jan 15, 2021 | Option Exercise | $61.28 | 5,856 | 358,856 | 31,826 | Jan 20, 2021, 07:00 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | EVP & General Counsel | Aug 31, 2020 | Option Exercise | $44.46 | 169 | 7,513 | 21,178 | Sep 02, 2020, 07:10 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP & General Counsel | Feb 29, 2020 | Option Exercise | $43.16 | 289 | 12,474 | 21,009 | Mar 03, 2020, 07:16 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP & General Counsel | Feb 10, 2020 | Sale | $59.60 | 3,882 | 231,367 | 20,720 | Feb 11, 2020, 05:40 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jan 15, 2020 | Option Exercise | $62.06 | 4,277 | 265,431 | 24,602 | Jan 17, 2020, 06:39 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Jul 01, 2019 | Option Exercise | $45.70 | 161 | 7,358 | 16,834 | Jul 02, 2019, 08:56 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Apr 04, 2019 | Option Exercise | $56.76 | 36,622 | 2,078,809 | 35,165 | Apr 05, 2019, 07:29 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Apr 04, 2019 | Sale | $83.79 | 39,622 | 3,319,929 | 19,673 | Apr 05, 2019, 07:29 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Apr 05, 2019 | Option Exercise | $61.68 | 2,252 | 138,903 | 18,925 | Apr 05, 2019, 07:29 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Apr 05, 2019 | Sale | $84.75 | 2,252 | 190,857 | 16,673 | Apr 05, 2019, 07:29 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Apr 03, 2019 | Option Exercise | $61.68 | 7,654 | 472,099 | 27,327 | Apr 05, 2019, 07:29 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Apr 03, 2019 | Sale | $84.83 | 7,654 | 649,289 | 19,673 | Apr 05, 2019, 07:29 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Mar 18, 2019 | Option Exercise | $61.57 | 28,800 | 1,773,216 | 48,473 | Mar 20, 2019, 06:15 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Mar 18, 2019 | Sale | $78.79 | 28,800 | 2,269,187 | 19,673 | Mar 20, 2019, 06:15 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Feb 27, 2019 | Sale | $68.01 | 26,800 | 1,822,580 | 19,673 | Mar 01, 2019, 05:40 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Feb 27, 2019 | Option Exercise | $45.11 | 26,800 | 1,208,952 | 33,773 | Mar 01, 2019, 05:40 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Feb 12, 2019 | Option Exercise | $39.87 | 275 | 10,964 | 19,948 | Feb 14, 2019, 06:01 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Feb 12, 2019 | Sale | $59.50 | 275 | 16,363 | 19,673 | Feb 14, 2019, 06:01 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Feb 05, 2019 | Option Exercise | $39.87 | 15,600 | 621,972 | 35,273 | Feb 05, 2019, 06:05 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Feb 05, 2019 | Sale | $59.50 | 15,600 | 928,200 | 19,673 | Feb 05, 2019, 06:05 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Feb 01, 2019 | Option Exercise | $39.87 | 4,000 | 159,480 | 23,673 | Feb 05, 2019, 06:05 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Feb 01, 2019 | Sale | $58.29 | 4,000 | 233,160 | 19,673 | Feb 05, 2019, 06:05 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Jan 15, 2019 | Option Exercise | $58.26 | 2,734 | 159,283 | 19,607 | Jan 17, 2019, 07:24 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Jan 01, 2019 | Option Exercise | $36.45 | 66 | 2,406 | 14,584 | Jan 03, 2019, 07:50 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Jan 03, 2019 | Option Exercise | $37.23 | 4,400 | 163,808 | 18,584 | Jan 03, 2019, 07:50 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Jan 03, 2019 | Sale | $54.80 | 4,400 | 241,120 | 14,584 | Jan 03, 2019, 07:50 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Jul 01, 2018 | Option Exercise | $35.42 | 66 | 2,338 | 14,518 | Jul 03, 2018, 03:28 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Mar 12, 2018 | Option Exercise | $10.82 | 1,000 | 10,820 | 15,452 | Mar 13, 2018, 09:14 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Mar 12, 2018 | Sale | $55.00 | 1,000 | 55,000 | 14,452 | Mar 13, 2018, 09:14 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Jan 29, 2018 | Option Exercise | $10.82 | 355 | 3,841 | 14,752 | Jan 31, 2018, 04:16 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Jan 29, 2018 | Sale | $55.00 | 355 | 19,525 | 14,452 | Jan 31, 2018, 04:16 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Jan 25, 2018 | Option Exercise | $10.82 | 645 | 6,979 | 15,097 | Jan 29, 2018, 04:08 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP Legal & General Counsel | Jan 25, 2018 | Sale | $55.00 | 645 | 35,475 | 14,452 | Jan 29, 2018, 04:08 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jan 16, 2018 | Sale | $51.76 | 2,697 | 139,597 | 14,452 | Jan 17, 2018, 09:25 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jan 01, 2018 | Option Exercise | $42.76 | 53 | 2,266 | 10,486 | Jan 02, 2018, 08:50 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Dec 01, 2017 | Sale | $55.50 | 1,000 | 55,500 | 10,433 | Dec 01, 2017, 07:03 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Dec 01, 2017 | Option Exercise | $10.82 | 1,000 | 10,820 | 11,433 | Dec 01, 2017, 07:03 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Nov 01, 2017 | Option Exercise | $10.82 | 1,000 | 10,820 | 11,433 | Nov 03, 2017, 05:20 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Nov 01, 2017 | Sale | $58.35 | 1,000 | 58,350 | 10,433 | Nov 03, 2017, 05:20 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Oct 05, 2017 | Option Exercise | $10.11 | 1,000 | 10,106 | 11,233 | Oct 06, 2017, 04:41 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Oct 05, 2017 | Sale | $55.00 | 1,000 | 55,000 | 10,433 | Oct 06, 2017, 04:41 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal and General Counsel | Sep 05, 2017 | Option Exercise | $7.25 | 200 | 1,450 | 10,633 | Sep 07, 2017, 08:23 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal and General Counsel | Sep 05, 2017 | Sale | $55.00 | 200 | 11,000 | 10,433 | Sep 07, 2017, 08:23 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal and General Counsel | Sep 06, 2017 | Option Exercise | $7.25 | 800 | 5,800 | 11,233 | Sep 07, 2017, 08:23 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal and General Counsel | Sep 06, 2017 | Sale | $55.00 | 800 | 44,000 | 10,433 | Sep 07, 2017, 08:23 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jul 01, 2017 | Option Exercise | $40.66 | 134 | 5,448 | 10,433 | Jul 03, 2017, 05:37 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jun 01, 2017 | Option Exercise | $10.82 | 70 | 757 | 10,369 | Jun 02, 2017, 06:15 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jun 01, 2017 | Sale | $48.00 | 70 | 3,360 | 10,299 | Jun 02, 2017, 06:15 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | May 01, 2017 | Option Exercise | $10.82 | 500 | 5,410 | 10,799 | May 03, 2017, 06:01 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | May 01, 2017 | Sale | $48.75 | 650 | 31,688 | 10,299 | May 03, 2017, 06:01 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Apr 24, 2017 | Option Exercise | $10.82 | 500 | 5,410 | 10,875 | Apr 26, 2017, 05:58 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Apr 24, 2017 | Sale | $45.00 | 500 | 22,500 | 10,449 | Apr 26, 2017, 05:58 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Apr 12, 2017 | Sale | $40.07 | 1,000 | 40,070 | 10,449 | Apr 13, 2017, 07:25 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Mar 01, 2017 | Option Exercise | $10.82 | 500 | 5,410 | 12,949 | Mar 02, 2017, 07:11 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Mar 01, 2017 | Sale | $49.29 | 1,500 | 73,935 | 12,449 | Mar 02, 2017, 07:11 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Feb 06, 2017 | Option Exercise | $10.68 | 500 | 5,342 | 12,930 | Feb 08, 2017, 06:32 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Feb 06, 2017 | Sale | $46.17 | 1,500 | 69,254 | 12,449 | Feb 08, 2017, 06:32 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jan 17, 2017 | Sale | $46.29 | 2,246 | 103,968 | 13,449 | Jan 18, 2017, 06:37 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jan 01, 2017 | Option Exercise | $20.76 | 424 | 8,801 | 9,950 | Jan 04, 2017, 06:34 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Dec 05, 2016 | Option Exercise | $10.82 | 350 | 3,787 | 9,876 | Dec 07, 2016, 07:27 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Dec 05, 2016 | Sale | $45.00 | 350 | 15,750 | 9,526 | Dec 07, 2016, 07:27 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Nov 14, 2016 | Sale | $45.00 | 1,000 | 45,000 | 9,526 | Nov 14, 2016, 06:53 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Nov 14, 2016 | Option Exercise | $10.82 | 1,000 | 10,820 | 10,332 | Nov 14, 2016, 06:53 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jul 01, 2016 | Option Exercise | $20.76 | 402 | 8,344 | 9,526 | Jul 01, 2016, 08:21 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Apr 06, 2016 | Option Exercise | $10.82 | 1,000 | 10,820 | 10,124 | Apr 07, 2016, 06:18 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Apr 06, 2016 | Sale | $45.00 | 1,000 | 45,000 | 9,124 | Apr 07, 2016, 06:18 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Mar 23, 2016 | Option Exercise | $10.82 | 1,000 | 10,820 | 10,124 | Mar 24, 2016, 07:13 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Mar 23, 2016 | Sale | $45.40 | 1,000 | 45,400 | 9,124 | Mar 24, 2016, 07:13 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jan 19, 2016 | Sale | $41.46 | 1,871 | 77,574 | 9,124 | Jan 19, 2016, 08:12 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jan 01, 2016 | Option Exercise | $47.71 | 43 | 2,052 | 6,302 | Jan 04, 2016, 09:25 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jan 04, 2016 | Option Exercise | $7.79 | 1,000 | 7,793 | 7,150 | Jan 04, 2016, 09:25 PM | |
| IONS | IONIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jan 04, 2016 | Sale | $61.10 | 1,000 | 61,100 | 6,302 | Jan 04, 2016, 09:25 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Dec 01, 2015 | Option Exercise | $7.25 | 1,000 | 7,250 | 7,259 | Dec 02, 2015, 06:49 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Dec 01, 2015 | Sale | $61.50 | 1,000 | 61,500 | 6,259 | Dec 02, 2015, 06:49 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Nov 03, 2015 | Option Exercise | $7.25 | 1,000 | 7,250 | 7,259 | Nov 04, 2015, 07:00 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Nov 03, 2015 | Sale | $51.95 | 1,000 | 51,950 | 6,259 | Nov 04, 2015, 07:00 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jul 01, 2015 | Option Exercise | $48.59 | 85 | 4,130 | 6,259 | Jul 02, 2015, 06:05 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Mar 19, 2015 | Sale | $74.85 | 30,525 | 2,284,757 | 6,174 | Mar 20, 2015, 06:55 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Mar 19, 2015 | Option Exercise | $22.62 | 30,525 | 690,416 | 16,699 | Mar 20, 2015, 06:55 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Mar 05, 2015 | Option Exercise | $9.63 | 5,800 | 55,865 | 10,307 | Mar 09, 2015, 07:27 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Mar 05, 2015 | Sale | $71.67 | 5,800 | 415,674 | 6,174 | Mar 09, 2015, 07:27 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | O'NEIL PATRICK R. | SVP, Legal & General Counsel | Jan 16, 2015 | Sale | $67.96 | 1,291 | 87,742 | 6,174 | Jan 20, 2015, 07:56 PM |
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