| Stock | Company | % Portfolio | Shares Held | Market Value | Change in Shares | % Change | Quarter End Price | Source |
|---|---|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A/S - ADR | 29.36% | 10,281,496 | $1,774,586,210 | No Change | $172.6 | 13F | |
| PCVX | VAXCYTE INC | 6.44% | 11,965,991 | $389,014,367 | -223,158 | -1.83% | $32.51 | 13F |
| RYTM | RHYTHM PHARMACEUTICALS INC | 5.81% | 5,561,359 | $351,422,275 | -523,053 | -8.6% | $63.19 | 13F |
| JANX | JANUX THERAPEUTICS INC | 4.28% | 11,189,693 | $258,481,908 | No Change | $23.1 | 13F | |
| CDTX | CIDARA THERAPEUTICS, INC. | 3.44% | 3,365,523 | $207,753,735 | No Change | 13D | ||
| RNA | AVIDITY BIOSCIENCES INC | 3.41% | 7,266,031 | $206,355,280 | 965,623 | 15.33% | $28.4 | 13F |
| ACLX | ARCELLX INC | 3.31% | 3,036,527 | $199,955,303 | No Change | $65.85 | 13F | |
| ETNB | 89BIO INC | 3.23% | 19,889,683 | $195,316,687 | No Change | $9.82 | 13F | |
| SPRY | ARS PHARMACEUTICALS INC | 3.14% | 10,860,977 | $189,524,049 | No Change | $17.45 | 13F | |
| NAMS | NEWAMSTERDAM PHARMA CO NV | 3.04% | 10,138,938 | $183,616,167 | No Change | $18.11 | 13F | |
| SION | SIONNA THERAPEUTICS INC | 3.00% | 10,445,322 | $181,226,337 | No Change | $17.35 | 13F | |
| EWTX | EDGEWISE THERAPEUTICS INC | 2.15% | 9,902,633 | $129,823,519 | 993,542 | 11.15% | $13.11 | 13F |
| LENZ | LENZ THERAPEUTICS INC | 2.03% | 4,178,823 | $122,481,302 | No Change | $29.31 | 13F | |
| WVE | WAVE LIFE SCIENCES LTD | 1.96% | 18,202,009 | $118,313,059 | No Change | $6.5 | 13F | |
| TYRA | TYRA BIOSCIENCES INC | 1.93% | 12,198,625 | $116,740,841 | 1,561,335 | 14.68% | $9.57 | 13F |
| GHRS | GH RESEARCH PLC | 1.55% | 7,676,697 | $93,578,936 | 732,049 | 10.54% | $12.19 | 13F |
| DYN | DYNE THERAPEUTICS INC | 1.53% | 9,714,392 | $92,481,012 | No Change | $9.52 | 13F | |
| GERN | GERON CORP | 1.41% | 60,379,366 | $85,134,906 | No Change | $1.41 | 13F | |
| IRON | DISC MEDICINE INC | 1.38% | 1,577,106 | $83,523,534 | No Change | $52.96 | 13F | |
| MLYS | MINERALYS THERAPEUTICS INC | 1.38% | 6,147,280 | $83,172,698 | No Change | $13.53 | 13F | |
| SEPN | SEPTERNA INC | 1.22% | 6,995,858 | $73,946,219 | No Change | $10.57 | 13F | |
| FULC | FULCRUM THERAPEUTICS INC | 1.16% | 10,229,099 | $70,376,201 | No Change | $6.88 | 13F | |
| BCAX | BICARA THERAPEUTICS INC | 1.07% | 6,955,993 | $64,621,175 | No Change | $9.29 | 13F | |
| VOR | VOR BIOPHARMA INC | 1.06% | 39,646,039 | $64,226,583 | No Change | $1.62 | 13F | |
| TSHA | TAYSHA GENE THERAPIES INC | 0.90% | 23,555,648 | $54,413,547 | 12,683,145 | 116.65% | $2.31 | 13F |
| DNTH | DIANTHUS THERAPEUTICS INC | 0.88% | 2,866,733 | $53,407,236 | No Change | $18.63 | 13F | |
| SLDB | SOLID BIOSCIENCES INC. | 0.81% | 7,997,510 | $48,304,960 | 2,186,187 | 37.62% | 13D | |
| RXST | RXSIGHT INC | 0.80% | 3,702,967 | $48,138,571 | -40,051 | -1.07% | $13 | 13F |
| SRRK | SCHOLAR ROCK HOLDING CORP | 0.67% | 1,136,453 | $40,253,165 | No Change | $35.42 | 13F | |
| TRML | TOURMALINE BIO INC | 0.67% | 2,538,925 | $40,597,411 | No Change | $15.99 | 13F | |
| CLYM | CLIMB BIO INC | 0.64% | 31,419,267 | $38,959,891 | No Change | $1.24 | 13F | |
| ASMB | Assembly Biosciences, Inc. | 0.60% | 1,530,615 | $36,122,514 | 1,530,615 | New | 13G | |
| GPCR | STRUCTURE THERAPEUTICS INC | 0.52% | 1,517,418 | $31,471,249 | No Change | $20.74 | 13F | |
| MTSR | METSERA INC | 0.32% | 675,525 | $19,218,686 | No Change | $28.45 | 13F | |
| MNPR | MONOPAR THERAPEUTICS INC | 0.30% | 511,207 | $18,290,986 | No Change | $35.78 | 13F | |
| NKTX | NKARTA INC | 0.30% | 10,805,129 | $17,936,514 | No Change | $1.66 | 13F | |
| ABOS | ACUMEN PHARMACEUTICALS INC | 0.29% | 14,932,063 | $17,321,193 | No Change | $1.16 | 13F | |
| LRMR | LARIMAR THERAPEUTICS INC | 0.29% | 6,045,351 | $17,471,064 | No Change | $2.89 | 13F | |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 0.28% | 4,563,211 | $16,929,513 | No Change | $3.71 | 13F | |
| ELVN | ENLIVEN THERAPEUTICS INC | 0.28% | 848,986 | $17,030,659 | No Change | $20.06 | 13F | |
| TVTX | TRAVERE THERAPEUTICS INC | 0.28% | 1,150,000 | $17,020,000 | No Change | $14.8 | 13F | |
| HNGE | HINGE HEALTH INC-A | 0.26% | 300,000 | $15,525,000 | 300,000 | New | $51.75 | 13F |
| ARTV | ARTIVA BIOTHERAPEUTICS INC | 0.25% | 9,853,302 | $14,878,486 | No Change | $1.51 | 13F | |
| PEPG | PEPGEN INC | 0.20% | 10,689,545 | $11,865,395 | No Change | $1.11 | 13F | |
| JBIO | JADE BIOSCIENCES INC | 0.18% | 1,062,326 | $10,612,637 | 1,062,326 | New | $9.99 | 13F |
| TNGX | TANGO THERAPEUTICS INC | 0.17% | 2,000,000 | $10,240,000 | 2,000,000 | New | $5.12 | 13F |
| ACRV | ACRIVON THERAPEUTICS INC | 0.16% | 8,340,508 | $9,925,205 | No Change | $1.19 | 13F | |
| ELDN | ELEDON PHARMACEUTICALS INC | 0.16% | 3,566,338 | $9,664,776 | No Change | $2.71 | 13F | |
| RCUS | ARCUS BIOSCIENCES INC | 0.15% | 1,136,364 | $9,250,003 | No Change | $8.14 | 13F | |
| CTNM | Contineum Therapeutics, Inc. | 0.15% | 2,122,000 | $9,230,700 | 2,122,000 | New | 13G | |
| PCSC | PERCEPTIVE CAPITAL SOLUTIONS | 0.13% | 750,000 | $7,965,000 | No Change | $10.62 | 13F | |
| BBNX | BETA BIONICS INC | 0.12% | 500,000 | $7,280,000 | No Change | $14.56 | 13F | |
| OMDA | OMADA HEALTH INC | 0.12% | 400,000 | $7,320,000 | 400,000 | New | $18.3 | 13F |
| HOWL | WEREWOLF THERAPEUTICS INC | 0.12% | 6,681,307 | $7,282,625 | 536,426 | 8.73% | $1.09 | 13F |
| CTMX | CYTOMX THERAPEUTICS INC | 0.10% | 2,661,331 | $6,041,221 | 1,661,331 | 166.13% | $2.27 | 13F |
| WGS | GENEDX HOLDINGS CORP | 0.09% | 58,044 | $5,358,042 | 58,044 | New | $92.31 | 13F |
| SRZN | SURROZEN INC | 0.09% | 602,626 | $5,387,476 | -76,504 | -11.27% | $8.94 | 13F |
| TXG | 10X GENOMICS INC-CLASS A | 0.09% | 475,343 | $5,504,472 | -1,468,904 | -75.55% | $11.58 | 13F |
| ACET | ADICET BIO INC | 0.08% | 7,541,000 | $4,600,010 | No Change | $0.61 | 13F | |
| AVTX | AVALO THERAPEUTICS INC | 0.08% | 932,973 | $4,655,535 | -34,027 | -3.52% | $4.99 | 13F |
| MBX | MBX BIOSCIENCES INC | 0.07% | 377,841 | $4,311,166 | -1,133,493 | -75% | $11.41 | 13F |
| TARA | PROTARA THERAPEUTIC INC | 0.05% | 1,039,295 | $3,149,064 | -2,360,705 | -69.43% | $3.03 | 13F |
| NAMSW | NEWAMSTERDAM PHARMA CO NV-27 | 0.04% | 333,333 | $2,666,664 | No Change | $8 | 13F | |
| ACHC | ACADIA HEALTHCARE CO INC | 0.03% | 89,262 | $2,025,355 | -127,738 | -58.87% | $22.69 | 13F |
| IFRX | INFLARX NV | 0.03% | 1,973,233 | $1,558,854 | 1,973,233 | New | $0.79 | 13F |
| ACRS | ACLARIS THERAPEUTICS INC | -4,666,667 | Exited | 13F | ||||
| AVTE | AEROVATE THERAPEUTICS INC | -9,192,092 | Exited | 13F | ||||
| ALEC | ALECTOR INC | -9,695,228 | Exited | 13F | ||||
| APGE | APOGEE THERAPEUTICS INC | -1,569,491 | Exited | 13F | ||||
| ATXS | ASTRIA THERAPEUTICS INC | -5,105,213 | Exited | 13F | ||||
| BCYC | BICYCLE THERAPEUTICS PLC-ADR | -1,093,477 | Exited | 13F | ||||
| BIOA | BIOAGE LABS INC | -1,052,494 | Exited | 13F | ||||
| BOLD | BOUNDLESS BIO INC | -2,180,631 | Exited | 13F | ||||
| DRUG | Bright Minds Biosciences Inc | -206,427 | Exited | 13F | ||||
| CBLL | CERIBELL INC | -824,582 | Exited | 13F | ||||
| DAWN | DAY ONE BIOPHARMACEUTICALS I | -5,755,577 | Exited | 13F | ||||
| EYPT | EYEPOINT PHARMACEUTICALS INC | -3,181,818 | Exited | 13F | ||||
| GKOS | GLAUKOS CORP | -190,256 | Exited | 13F | ||||
| HUMA | HUMACYTE INC | -3,312,356 | Exited | 13F | ||||
| IDYA | IDEAYA BIOSCIENCES INC | -1,347,252 | Exited | 13F | ||||
| INSM | INSMED INC | -200,000 | Exited | 13F | ||||
| ITOS | ITEOS THERAPEUTICS INC | -3,649,057 | Exited | 13F | ||||
| KURA | KURA ONCOLOGY INC | -4,004,610 | Exited | 13F | ||||
| LXEO | LEXEO THERAPEUTICS INC | -546,554 | Exited | 13F | ||||
| NRIX | NURIX THERAPEUTICS INC | -1,333,333 | Exited | 13F | ||||
| SCLX | SCILEX HOLDING CO | -1,036,218 | Exited | 13F | ||||
| SERA | SERA PROGNOSTICS INC-A | -3,032,808 | Exited | 13F | ||||
| STRO | SUTRO BIOPHARMA INC | -4,434,637 | Exited | 13F | ||||
| XNCR | XENCOR INC | -575,000 | Exited | 13F | ||||
| ZLAB | ZAI LAB LTD-ADR | -1,295,040 | Exited | 13F | ||||
| ZURA | ZURA BIO LTD | -3,217,503 | Exited | 13F | ||||
| URGN | UROGEN PHARMA LTD | -3,206,271 | Exited | 13F | ||||
| IMTX | IMMATICS NV | -1,750,000 | Exited | 13F |