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RA CAPITAL MANAGEMENT, L.P. (Data extracted from 13F, 13D, 13G and Form 4)

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RA CAPITAL MANAGEMENT, L.P.

AUM: $11.32 B

13-F Portfolio Value: $9.44 B

Last 13-F Filed: Q1 2026

Concentration in top 10: 61.29%

Stock	Company	% Portfolio	Shares Held	Market Value	Change in Shares	% Change	Quarter End Price	Source
PCVX	VAXCYTE INC	5.53%	11,474,599	$666,788,948	750,000	6.99%	$58.11	13F
CLYM	Climb Bio, Inc.	3.08%	23,249,186	$299,914,499	11,948,247	105.73%		13D
WVE	WAVE LIFE SCIENCES LTD.	2.30%	34,225,506	$259,771,591	7,250,001	26.88%		13D
NUVL	NUVALENT INC-A	2.16%	2,534,145	$259,623,155	654,088	34.79%	$102.45	13F
DNTH	DIANTHUS THERAPEUTICS INC	1.82%	2,611,733	$219,176,633	1,000,000	62.05%	$83.92	13F
MLYS	MINERALYS THERAPEUTICS INC	1.73%	7,692,750	$208,396,598	369,000	5.04%	$27.09	13F
ARTV	Artiva Biotherapeutics, Inc.	1.43%	18,137,650	$162,331,968	8,284,348	84.08%		Form 4
IRON	DISC MEDICINE INC	1.30%	2,450,221	$156,667,131	474,089	23.99%	$63.94	13F
BCAX	BICARA THERAPEUTICS INC	1.20%	7,255,993	$144,321,701	300,000	4.31%	$19.89	13F
SLDB	SOLID BIOSCIENCES INC.	1.02%	12,036,126	$99,899,846	2,696,148	28.87%		13D
EVMN	EVOMMUNE INC	0.67%	3,494,638	$80,341,728	35,868	1.04%	$22.99	13F
ABOS	ACUMEN PHARMACEUTICALS INC	0.41%	20,992,669	$49,542,699	6,060,606	40.59%	$2.36	13F
DSGN	DESIGN THERAPEUTICS INC	0.26%	2,972,973	$31,632,433	1,511,592	103.44%	$10.64	13F
ACRV	ACRIVON THERAPEUTICS, INC.	0.22%	12,284,906	$24,201,265	3,944,398	47.29%		13D
INSP	INSPIRE MEDICAL SYSTEMS INC	0.14%	325,663	$16,797,698	183,699	129.4%	$51.58	13F
HNGE	HINGE HEALTH INC-A	0.12%	364,613	$14,059,477	284,500	355.12%	$38.56	13F
WGS	GENEDX HOLDINGS CORP	0.11%	209,887	$13,478,943	151,843	261.6%	$64.22	13F
WAY	WAYSTAR HOLDING CORP	0.11%	529,400	$12,763,834	385,000	266.62%	$24.11	13F
ACET	ADICET BIO INC	0.07%	1,182,624	$8,053,669	234,375	24.72%	$6.81	13F