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| Stock | Company | % Portfolio | Shares Held | Market Value | Change in Shares | % Change | Quarter End Price | Source |
|---|---|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A/S - ADR | 19.50% | 10,108,400 | $1,528,086,828 | 1,000 | 0.00989% | $151.17 | 13F |
| PCVX | VAXCYTE INC | 7.15% | 8,203,754 | $560,398,436 | 312,500 | 3.96% | $68.31 | 13F |
| LEGN | LEGEND BIOTECH CORP-ADR | 4.91% | 6,861,097 | $384,838,931 | 596,390 | 9.52% | $56.09 | 13F |
| JANX | JANUX THERAPEUTICS INC | 4.40% | 9,165,652 | $345,086,798 | No Change | $37.65 | 13F | |
| RYTM | RHYTHM PHARMACEUTICALS INC | 2.95% | 5,330,412 | $230,966,752 | No Change | $43.33 | 13F | |
| EVH | EVOLENT HEALTH INC - A | 2.40% | 5,736,132 | $188,087,768 | 3,187,000 | 125.02% | $32.79 | 13F |
| NAMS | NEWAMSTERDAM PHARMA CO NV | 2.37% | 7,864,000 | $185,983,600 | No Change | $23.65 | 13F | |
| AVTE | Aerovate Therapeutics, Inc. | 2.33% | 8,313,982 | $180,829,109 | 50,000 | 0.61% | 13D | |
| RXST | RXSIGHT INC | 2.27% | 3,442,825 | $177,580,914 | 38,540 | 1.13% | $51.58 | 13F |
| TYRA | TYRA BIOSCIENCES INC | 2.18% | 10,416,609 | $170,832,388 | 3,180,155 | 43.95% | $16.4 | 13F |
| EWTX | EDGEWISE THERAPEUTICS INC | 2.07% | 8,909,091 | $162,501,820 | 8,909,091 | New | $18.24 | 13F |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 2.05% | 5,051,511 | $160,941,140 | 888,300 | 21.34% | $31.86 | 13F |
| BIIB | BIOGEN INC | 2.04% | 740,727 | $159,722,963 | 207,835 | 39% | $215.63 | 13F |
| PEPG | PEPGEN INC | 2.01% | 10,689,545 | $157,136,312 | 2,557,593 | 31.45% | $14.7 | 13F |
| GERN | GERON CORP | 1.95% | 46,202,425 | $152,468,003 | No Change | $3.3 | 13F | |
| ETNB | 89BIO INC | 1.90% | 12,766,948 | $148,607,275 | 1,350,000 | 11.82% | $11.64 | 13F |
| DYN | DYNE THERAPEUTICS INC | 1.80% | 4,954,779 | $140,666,176 | 4,954,779 | New | $28.39 | 13F |
| APGE | APOGEE THERAPEUTICS INC | 1.68% | 1,977,901 | $131,431,521 | No Change | $66.45 | 13F | |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 1.65% | 7,809,852 | $129,018,755 | No Change | $16.52 | 13F | |
| RNA | Avidity Biosciences, Inc. | 1.52% | 4,895,959 | $119,265,561 | 1,613,779 | 49.17% | 13G | |
| NKTX | NKARTA INC | 1.49% | 10,805,129 | $116,803,444 | 3,000,000 | 38.44% | $10.81 | 13F |
| WVE | WAVE LIFE SCIENCES LTD | 1.43% | 18,202,009 | $112,306,396 | No Change | $6.17 | 13F | |
| SPRY | ARS PHARMACEUTICALS INC | 1.42% | 10,860,977 | $110,999,185 | 1,401,299 | 14.81% | $10.22 | 13F |
| FULC | FULCRUM THERAPEUTICS INC | 1.40% | 11,609,704 | $109,595,606 | No Change | $9.44 | 13F | |
| VRNA | VERONA PHARMA PLC - ADR | 1.30% | 6,317,990 | $101,656,459 | No Change | $16.09 | 13F | |
| LENZ | LENZ THERAPEUTICS INC | 1.19% | 4,178,823 | $93,313,118 | 4,178,823 | New | $22.33 | 13F |
| INBX | INHIBRX INC | 1.17% | 2,629,837 | $91,939,102 | -2,094,370 | -44.33% | $34.96 | 13F |
| AXSM | AXSOME THERAPEUTICS INC | 1.02% | 1,000,000 | $79,800,000 | No Change | $79.8 | 13F | |
| ACRV | Acrivon Therapeutics, Inc. | 0.99% | 8,359,102 | $77,656,058 | 3,548,594 | 73.77% | 13D | |
| LBPH | LONGBOARD PHARMACEUTICALS IN | 0.91% | 3,289,119 | $71,044,970 | 3,289,119 | New | $21.6 | 13F |
| DNTH | DIANTHUS THERAPEUTICS INC | 0.89% | 2,333,000 | $69,990,000 | 2,333,000 | New | $30 | 13F |
| GHRS | GH RESEARCH PLC | 0.85% | 6,251,714 | $66,643,271 | 664,381 | 11.89% | $10.66 | 13F |
| GPCR | STRUCTURE THERAPEUTICS INC | 0.83% | 1,510,362 | $64,734,115 | 1,023,530 | 210.24% | $42.86 | 13F |
| ITOS | iTeos Therapeutics, Inc. | 0.82% | 3,659,046 | $63,813,762 | -758,213 | -17.16% | 13D | |
| MLYS | MINERALYS THERAPEUTICS INC | 0.80% | 4,850,984 | $62,626,203 | 1,672,508 | 52.62% | $12.91 | 13F |
| ATXS | ASTRIA THERAPEUTICS INC | 0.79% | 4,413,150 | $62,115,086 | 4,413,150 | New | $14.07 | 13F |
| ABOS | ACUMEN PHARMACEUTICALS INC | 0.77% | 14,932,063 | $60,474,855 | No Change | $4.05 | 13F | |
| SLDB | SOLID BIOSCIENCES INC | 0.74% | 4,330,446 | $57,681,541 | 904,160 | 26.39% | $13.32 | 13F |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 0.70% | 204,500 | $54,609,680 | No Change | $267.04 | 13F | |
| VOR | VOR BIOPHARMA INC | 0.69% | 22,748,880 | $53,914,846 | No Change | $2.37 | 13F | |
| PRAX | PRAXIS PRECISION MEDICINES I | 0.65% | 828,380 | $50,547,748 | 828,380 | New | $61.02 | 13F |
| LRMR | LARIMAR THERAPEUTICS INC | 0.59% | 6,045,351 | $45,884,214 | 6,045,351 | New | $7.59 | 13F |
| URGN | UROGEN PHARMA LTD | 0.59% | 3,083,430 | $46,251,450 | No Change | $15 | 13F | |
| CTKB | CYTEK BIOSCIENCES INC | 0.58% | 6,809,404 | $45,691,101 | No Change | $6.71 | 13F | |
| CCCC | C4 THERAPEUTICS INC | 0.51% | 4,878,000 | $39,853,260 | No Change | $8.17 | 13F | |
| ELVN | ENLIVEN THERAPEUTICS INC | 0.48% | 2,122,465 | $37,334,159 | No Change | $17.59 | 13F | |
| HOWL | Werewolf Therapeutics, Inc. | 0.48% | 6,192,881 | $37,590,788 | 48,000 | 0.78% | 13D | |
| ELYM | Eliem Therapeutics, Inc. | 0.45% | 13,189,736 | $35,216,595 | 38,887 | 0.30% | 13D | |
| TSHA | TAYSHA GENE THERAPIES INC | 0.40% | 10,872,503 | $31,204,084 | -7,600,000 | -41.14% | $2.87 | 13F |
| MGNX | MACROGENICS INC | 0.39% | 2,082,021 | $30,647,349 | -1,971,056 | -48.63% | $14.72 | 13F |
| BOLD | Boundless Bio, Inc. | 0.38% | 1,884,787 | $30,156,592 | -295,844 | -13.57% | Form 4 | |
| TNYA | TENAYA THERAPEUTICS INC | 0.38% | 5,755,050 | $30,098,912 | 247,703 | 4.5% | $5.23 | 13F |
| CYBN | CYBIN INC | 0.31% | 58,139,535 | $24,040,698 | 58,139,535 | New | $0.41 | 13F |
| ANRO | ALTO NEUROSCIENCE INC | 0.27% | 1,385,491 | $21,267,287 | 1,385,491 | New | $15.35 | 13F |
| BDTX | Black Diamond Therapeutics, Inc. | 0.26% | 2,788,028 | $20,073,802 | -737,726 | -20.92% | 13D | |
| VXRT | VAXART INC | 0.26% | 15,384,615 | $20,000,000 | 15,384,615 | New | $1.3 | 13F |
| BCYC | BICYCLE THERAPEUTICS PLC-ADR | 0.25% | 800,000 | $19,920,000 | No Change | $24.9 | 13F | |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 0.25% | 938,591 | $19,400,676 | 938,591 | New | $20.67 | 13F |
| CRVO | CervoMed Inc. | 0.24% | 825,373 | $18,735,967 | -36,200 | -4.20% | 13G | |
| PLRX | PLIANT THERAPEUTICS INC | 0.24% | 1,281,000 | $19,086,900 | No Change | $14.9 | 13F | |
| SERA | SERA PROGNOSTICS INC-A | 0.24% | 2,024,221 | $18,420,411 | 2,024,221 | New | $9.1 | 13F |
| THRD | THIRD HARMONIC BIO INC | 0.24% | 2,033,056 | $19,192,049 | No Change | $9.44 | 13F | |
| ACET | ADICET BIO INC | 0.23% | 7,541,000 | $17,721,350 | 7,541,000 | New | $2.35 | 13F |
| ANTX | AN2 THERAPEUTICS INC | 0.23% | 5,551,295 | $18,041,709 | No Change | $3.25 | 13F | |
| MGX | METAGENOMI INC | 0.23% | 1,744,415 | $18,403,578 | 1,744,415 | New | $10.55 | 13F |
| RGLS | REGULUS THERAPEUTICS INC | 0.23% | 6,250,000 | $18,000,000 | 6,250,000 | New | $2.88 | 13F |
| IMTX | IMMATICS NV | 0.23% | 1,750,000 | $18,392,500 | 1,750,000 | New | $10.51 | 13F |
| ARVN | ARVINAS INC | 0.22% | 421,348 | $17,393,245 | No Change | $41.28 | 13F | |
| ZURA | Zura Bio Ltd | 0.14% | 3,217,503 | $10,649,935 | 3,217,503 | New | 13G | |
| LXEO | LEXEO THERAPEUTICS INC | 0.13% | 660,938 | $10,363,508 | 660,938 | New | $15.68 | 13F |
| CMRX | CHIMERIX INC | 0.12% | 8,800,000 | $9,328,000 | No Change | $1.06 | 13F | |
| IGMS | IGM BIOSCIENCES INC | 0.12% | 937,500 | $9,046,875 | No Change | $9.65 | 13F | |
| CMPS | COMPASS PATHWAYS PLC | 0.08% | 791,359 | $6,584,107 | -494,641 | -38.46% | $8.32 | 13F |
| TARA | Protara Therapeutics, Inc. | 0.08% | 2,073,075 | $6,613,109 | 2,073,075 | New | 13G | |
| CVAC | CUREVAC NV | 0.08% | 1,965,707 | $5,956,092 | -778,563 | -28.37% | $3.03 | 13F |
| UNCY | UNICYCIVE THERAPEUTICS INC | 0.06% | 3,470,688 | $4,789,549 | No Change | $1.38 | 13F | |
| SRZN | Surrozen, Inc./DE | 0.05% | 323,662 | $3,667,090 | 323,662 | New | 13G | |
| NAMSW | NEWAMSTERDAM PHARMA CO NV-27 | 0.05% | 333,333 | $3,679,996 | No Change | $11.04 | 13F | |
| MDNA | Medicenna Therapeutics Corp. | 0.02% | 7,714,760 | $1,211,217 | 7,714,760 | New | 13G | |
| ALPN | ALPINE IMMUNE SCIENCES INC | -4,909,763 | Exited | 13F | ||||
| CNTB | CONNECT BIOPHARMA HOLDINGS L | -3,062,871 | Exited | 13F | ||||
| CBAY | CYMABAY THERAPEUTICS INC | -6,940,000 | Exited | 13F | ||||
| HARP | HARPOON THERAPEUTICS INC | -1,500,000 | Exited | 13F | ||||
| ICVX | ICOSAVAX INC | -5,963,565 | Exited | 13F | ||||
| IMGN | IMMUNOGEN INC | -23,750,601 | Exited | 13F | ||||
| SABS | SAB BIOTHERAPEUTICS INC | -2,374,081 | Exited | 13F |