| Stock | Company | % Portfolio | Shares Held | Market Value | Change in Shares | % Change | Quarter End Price | Source |
|---|---|---|---|---|---|---|---|---|
| INCY | Incyte Corporation | 19.58% | 30,743,275 | $2,093,617,028 | 3,322 | 0.01% | $68.1 | 13F |
| ACAD | ACADIA Pharmaceuticals Inc. | 8.65% | 42,896,690 | $925,281,603 | 18,774 | 0.04% | $21.57 | 13F |
| INSM | Insmed Incorporated | 7.26% | 7,712,900 | $776,226,256 | 2,332,274 | 43.35% | $100.64 | 13F |
| SMMT | Summit Therapeutics Inc. | 6.71% | 33,722,974 | $717,624,887 | 9,298,109 | 38.07% | $21.28 | 13F |
| RVMD | Revolution Medicines, Inc. | 3.22% | 9,364,972 | $344,537,320 | 1,428,000 | 17.99% | $36.79 | 13F |
| CELC | Celcuity Inc. | 2.93% | 7,745,692 | $309,130,568 | 2,295,247 | 42.11% | 13D | |
| KYMR | Kymera Therapeutics, Inc. | 2.71% | 6,651,429 | $290,268,362 | 655,500 | 10.93% | $43.64 | 13F |
| ALKS | Alkermes plc | 1.72% | 6,410,603 | $183,407,352 | 1,927,318 | 42.99% | $28.61 | 13F |
| RARE | Ultragenyx Pharmaceutical Inc. | 0.94% | 2,772,692 | $100,815,081 | 1,196,578 | 75.92% | $36.36 | 13F |
| EWTX | Edgewise Therapeutics, Inc. | 0.90% | 7,305,940 | $95,780,873 | 1,150,000 | 18.68% | $13.11 | 13F |
| KNSA | Kiniksa Pharmaceuticals International, plc | 0.73% | 2,824,669 | $78,158,591 | 6,346 | 0.23% | $27.67 | 13F |
| IMTX | Immatics N.V. | 0.51% | 10,168,901 | $54,708,687 | 2,893,071 | 39.76% | $5.38 | 13F |
| GPCR | Structure Therapeutics Inc. | 0.49% | 2,508,767 | $52,031,828 | 2,147,202 | 593.86% | $20.74 | 13F |
| IDYA | IDEAYA Biosciences, Inc. | 0.42% | 2,118,728 | $44,535,663 | 1,056,605 | 99.48% | $21.02 | 13F |
| BNTX | BioNTech SE | 0.37% | 368,923 | $39,279,232 | 323,892 | 719.26% | $106.47 | 13F |
| MRUS | Merus N.V. | 0.28% | 574,377 | $30,212,230 | 350,877 | 156.99% | $52.6 | 13F |
| PRAX | Praxis Precision Medicines, Inc. | 0.27% | 689,488 | $28,992,970 | 357,955 | 107.97% | $42.05 | 13F |
| NTLA | Intellia Therapeutics, Inc. | 0.23% | 2,675,674 | $25,097,822 | 2,031,558 | 315.4% | $9.38 | 13F |
| IRON | Disc Medicine, Inc. | 0.17% | 337,050 | $17,850,168 | 260,000 | 337.44% | $52.96 | 13F |
| CLDX | Celldex Therapeutics, Inc. | 0.13% | 665,370 | $13,540,280 | 417,726 | 168.68% | $20.35 | 13F |
| XENE | Xenon Pharmaceuticals Inc. | 0.11% | 370,208 | $11,587,510 | 22,800 | 6.56% | $31.3 | 13F |