| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Aug 15, 2025 | Option/RSU Exercise | - | 31,686 | - | 177,423 | Aug 19, 2025, 07:37 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Aug 18, 2025 | Sale | $6.77 | 16,058 | 108,666 | 161,365 | Aug 19, 2025, 07:37 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Jul 10, 2025 | Gift | - | 601,259 | - | 147,702 | Jul 14, 2025, 04:18 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Jul 02, 2024 | Gift | - | 199,202 | - | 1,228,868 | Jul 14, 2025, 04:18 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Jul 10, 2025 | Gift | - | 402,057 | - | 1,408,285 | Jul 14, 2025, 04:18 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | May 15, 2025 | Option/RSU Exercise | - | 31,686 | - | 159,701 | May 19, 2025, 05:44 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | May 16, 2025 | Sale | $6.26 | 13,964 | 87,385 | 145,737 | May 19, 2025, 05:44 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Feb 15, 2025 | Option/RSU Exercise | - | 31,686 | - | 140,063 | Feb 21, 2025, 06:05 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Feb 18, 2025 | Sale | $11.96 | 12,048 | 144,130 | 128,015 | Feb 21, 2025, 06:05 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Nov 15, 2024 | Option/RSU Exercise | - | 19,999 | - | 118,931 | Nov 19, 2024, 04:36 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Nov 18, 2024 | Sale | $13.21 | 10,554 | 139,420 | 108,377 | Nov 19, 2024, 04:36 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Aug 15, 2024 | Option/RSU Exercise | - | 19,999 | - | 109,613 | Aug 19, 2024, 05:53 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Aug 16, 2024 | Sale | $14.00 | 10,681 | 149,524 | 98,932 | Aug 19, 2024, 05:53 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Jul 02, 2024 | Gift | - | 241,912 | - | 222,030 | Jul 05, 2024, 06:11 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Jul 02, 2024 | Gift | - | 241,912 | - | 807,026 | Jul 05, 2024, 06:11 PM |
| MREO | | Mereo BioPharma Group plc | Jeremy Bender | Director | Jun 17, 2024 | Award/Grant | $3.99 | 12,550 | 50,075 | 12,550 | Jun 17, 2024, 04:15 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | May 15, 2024 | Option/RSU Exercise | - | 19,999 | - | 662,601 | May 17, 2024, 06:27 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | May 16, 2024 | Sale | $16.08 | 7,873 | 126,588 | 654,728 | May 17, 2024, 06:27 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | May 03, 2024 | Sale | $17.85 | 9,154 | 163,417 | 642,602 | May 03, 2024, 06:48 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | May 01, 2024 | Sale | $17.88 | 70,051 | 1,252,183 | 651,762 | May 03, 2024, 06:48 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | May 02, 2024 | Sale | $17.94 | 6 | 108 | 651,756 | May 03, 2024, 06:48 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Feb 15, 2024 | Option/RSU Exercise | - | 19,999 | - | 729,428 | Feb 20, 2024, 06:14 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | CHIEF EXECUTIVE OFFICER | Feb 16, 2024 | Sale | $15.25 | 7,615 | 116,114 | 721,813 | Feb 20, 2024, 06:14 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Nov 15, 2023 | Option/RSU Exercise | - | 8,312 | - | 712,536 | Nov 17, 2023, 06:20 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Nov 16, 2023 | Sale | $11.69 | 3,107 | 36,321 | 709,429 | Nov 17, 2023, 06:20 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Aug 15, 2023 | Option/RSU Exercise | - | 8,312 | - | 707,220 | Aug 17, 2023, 06:16 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Aug 17, 2023 | Sale | $13.86 | 2,996 | 41,525 | 704,224 | Aug 17, 2023, 06:16 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Jul 01, 2023 | Gift | - | 240,288 | - | 698,908 | Jul 05, 2023, 07:47 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Jul 01, 2023 | Gift | - | 240,288 | - | 0 | Jul 05, 2023, 07:47 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Jul 01, 2023 | Gift | - | 659,926 | - | 300,025 | Jul 05, 2023, 07:47 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | May 15, 2023 | Option/RSU Exercise | - | 8,312 | - | 1,182,588 | May 17, 2023, 06:27 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | May 16, 2023 | Sale | $13.12 | 3,104 | 40,732 | 1,179,484 | May 17, 2023, 06:27 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Mar 07, 2023 | Sale | $20.01 | 12,500 | 250,114 | 1,174,276 | Mar 08, 2023, 05:50 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Feb 15, 2023 | Option/RSU Exercise | - | 8,312 | - | 1,189,798 | Feb 17, 2023, 05:26 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Feb 16, 2023 | Sale | $19.57 | 3,022 | 59,150 | 1,186,776 | Feb 17, 2023, 05:26 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Jan 23, 2023 | Sale | $22.00 | 12,500 | 274,988 | 1,181,486 | Jan 24, 2023, 05:11 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Dec 21, 2022 | Sale | $20.32 | 12,500 | 253,969 | 1,192,424 | Dec 22, 2022, 05:50 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Nov 21, 2022 | Sale | $20.76 | 12,500 | 259,479 | 1,205,324 | Nov 22, 2022, 06:43 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Nov 15, 2022 | Option/RSU Exercise | - | 3,562 | - | 1,218,937 | Nov 17, 2022, 05:33 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Nov 16, 2022 | Sale | $21.46 | 1,513 | 32,469 | 1,217,424 | Nov 17, 2022, 05:33 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Nov 01, 2022 | Sale | $20.03 | 12,500 | 250,355 | 1,215,375 | Nov 03, 2022, 05:30 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Oct 03, 2022 | Sale | $20.05 | 12,500 | 250,646 | 1,227,875 | Oct 05, 2022, 04:22 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Sep 01, 2022 | Sale | $23.25 | 12,500 | 290,581 | 1,242,234 | Sep 06, 2022, 07:50 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Sep 01, 2022 | Sale | $23.25 | 12,500 | 290,581 | 1,242,234 | Sep 06, 2022, 07:49 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Aug 15, 2022 | Option/RSU Exercise | - | 10,686 | - | 1,256,878 | Aug 17, 2022, 07:24 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Aug 16, 2022 | Sale | $24.31 | 4,003 | 97,313 | 1,252,875 | Aug 17, 2022, 07:24 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Aug 04, 2022 | Sale | $20.00 | 12,500 | 250,021 | 1,246,192 | Aug 05, 2022, 05:19 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Jul 18, 2022 | Sale | $20.00 | 2,600 | 52,003 | 1,258,692 | Jul 20, 2022, 06:17 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Jul 08, 2022 | Sale | $20.00 | 1,795 | 35,900 | 1,261,292 | Jul 12, 2022, 07:30 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Jul 01, 2022 | Sale | $20.00 | 1,746 | 34,920 | 1,263,944 | Jul 06, 2022, 08:56 PM |
| DAWN | | Day One Biopharmaceuticals, Inc. | Jeremy Bender | Chief Executive Officer | Jul 05, 2022 | Sale | $20.00 | 857 | 17,140 | 1,263,087 | Jul 06, 2022, 08:56 PM |
