| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Aug 18, 2025 | Sale | $157.60 | 800 | 126,080 | 24,116 | Aug 20, 2025, 04:45 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Aug 07, 2025 | Sale | $150.04 | 400 | 60,016 | 24,916 | Aug 08, 2025, 04:18 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Jun 05, 2025 | Gift | - | 385 | - | 25,316 | Jun 09, 2025, 04:21 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 30, 2025 | Award/Grant | $135.63 | 6,709 | 909,942 | 25,856 | Jun 03, 2025, 04:58 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 31, 2025 | Tax Payment (Shares) | $135.63 | 155 | 21,023 | 25,701 | Jun 03, 2025, 04:58 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 26, 2025 | Tax Payment (Shares) | $136.73 | 161 | 22,014 | 19,352 | May 29, 2025, 05:05 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 27, 2025 | Tax Payment (Shares) | $136.73 | 122 | 16,681 | 19,230 | May 29, 2025, 05:05 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 28, 2025 | Tax Payment (Shares) | $138.65 | 83 | 11,508 | 19,147 | May 29, 2025, 05:05 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 13, 2025 | Sale | $145.41 | 500 | 72,705 | 19,513 | May 15, 2025, 04:38 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 20, 2025 | Sale | $162.50 | 4,400 | 715,000 | 20,013 | Feb 21, 2025, 04:36 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Jan 31, 2025 | Tax Payment (Shares) | $165.57 | 846 | 140,072 | 24,413 | Feb 03, 2025, 04:58 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Aug 08, 2024 | Sale | $199.36 | 1,780 | 354,861 | 22,521 | Aug 12, 2024, 04:13 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Jun 03, 2024 | Gift | - | 311 | - | 24,301 | Jun 04, 2024, 04:46 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 29, 2024 | Tax Payment (Shares) | $214.51 | 223 | 47,836 | 22,501 | May 31, 2024, 04:19 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 26, 2024 | Tax Payment (Shares) | $217.21 | 243 | 52,782 | 23,033 | May 28, 2024, 05:29 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 27, 2024 | Tax Payment (Shares) | $217.21 | 184 | 39,967 | 22,849 | May 28, 2024, 05:29 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 28, 2024 | Tax Payment (Shares) | $217.21 | 125 | 27,151 | 22,724 | May 28, 2024, 05:29 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 10, 2024 | Sale | $226.97 | 1,304 | 295,969 | 23,276 | May 14, 2024, 04:49 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Jan 29, 2024 | Tax Payment (Shares) | $220.28 | 994 | 218,958 | 25,418 | Mar 25, 2024, 05:55 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 15, 2024 | Sale | $238.93 | 838 | 200,223 | 24,620 | Feb 20, 2024, 05:20 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Jan 29, 2024 | Tax Payment (Shares) | $220.28 | 1,025 | 225,787 | 25,458 | Jan 31, 2024, 05:28 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Nov 30, 2023 | Sale | $197.73 | 1,850 | 365,800 | 23,133 | Dec 01, 2023, 04:10 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Nov 09, 2023 | Option/RSU Exercise | $144.67 | 9,128 | 1,320,548 | 34,111 | Nov 13, 2023, 04:12 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Nov 09, 2023 | Sale | $173.48 | 9,128 | 1,583,522 | 31,526 | Nov 13, 2023, 04:12 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Aug 10, 2023 | Sale | $216.52 | 700 | 151,564 | 24,983 | Aug 14, 2023, 04:11 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 27, 2023 | Tax Payment (Shares) | $194.12 | 184 | 35,718 | 26,031 | May 31, 2023, 06:10 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 28, 2023 | Tax Payment (Shares) | $194.12 | 125 | 24,265 | 25,906 | May 31, 2023, 06:10 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 29, 2023 | Tax Payment (Shares) | $194.12 | 223 | 43,289 | 25,683 | May 31, 2023, 06:10 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 15, 2023 | Sale | $190.39 | 345 | 65,685 | 24,026 | May 16, 2023, 02:18 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 12, 2023 | Sale | $193.03 | 959 | 185,116 | 24,380 | May 15, 2023, 02:49 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 22, 2023 | Tax Payment (Shares) | $243.60 | 317 | 77,221 | 25,330 | Feb 22, 2023, 04:24 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Jan 27, 2023 | Tax Payment (Shares) | $244.29 | 3,261 | 796,630 | 25,647 | Jan 30, 2023, 04:39 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Dec 01, 2022 | Option/RSU Exercise | $109.34 | 6,409 | 700,760 | 26,641 | Dec 05, 2022, 04:55 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Dec 01, 2022 | Sale | $224.25 | 6,409 | 1,437,205 | 25,503 | Dec 05, 2022, 04:55 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Nov 04, 2022 | Sale | $216.36 | 534 | 115,536 | 20,232 | Nov 07, 2022, 06:54 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Jul 06, 2022 | Gift | - | 195 | - | 20,966 | Aug 08, 2022, 03:03 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Aug 05, 2022 | Sale | $226.13 | 200 | 45,227 | 20,766 | Aug 08, 2022, 03:03 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 28, 2022 | Tax Payment (Shares) | $244.41 | 125 | 30,551 | 21,384 | May 31, 2022, 07:09 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 29, 2022 | Tax Payment (Shares) | $244.41 | 223 | 54,503 | 21,161 | May 31, 2022, 07:09 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 23, 2022 | Sale | $292.75 | 395 | 115,636 | 19,852 | Feb 24, 2022, 06:37 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 18, 2022 | Sale | $291.80 | 1,143 | 333,527 | 21,275 | Feb 23, 2022, 04:44 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 22, 2022 | Tax Payment (Shares) | $293.61 | 317 | 93,074 | 20,958 | Feb 23, 2022, 04:44 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 22, 2022 | Sale | $290.83 | 396 | 115,170 | 20,954 | Feb 23, 2022, 04:44 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 23, 2022 | Tax Payment (Shares) | $289.58 | 315 | 91,218 | 20,247 | Feb 23, 2022, 04:44 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 14, 2022 | Gift | - | 150 | - | 21,675 | Feb 23, 2022, 04:44 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 18, 2022 | Option/RSU Exercise | $88.05 | 743 | 65,421 | 22,418 | Feb 23, 2022, 04:44 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Jan 28, 2022 | Tax Payment (Shares) | $312.24 | 4,570 | 1,426,937 | 21,825 | Feb 01, 2022, 05:39 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Nov 22, 2021 | Gift | - | 182 | - | 8,280 | Dec 27, 2021, 03:43 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Aug 06, 2021 | Sale | $402.21 | 3,700 | 1,488,175 | 10,704 | Aug 10, 2021, 11:56 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 29, 2021 | Tax Payment (Shares) | $337.99 | 223 | 75,372 | 12,162 | Jun 01, 2021, 06:03 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 25, 2021 | Option/RSU Exercise | $88.05 | 2,750 | 242,138 | 19,996 | Feb 26, 2021, 04:51 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 25, 2021 | Sale | $281.70 | 8,735 | 2,460,616 | 17,984 | Feb 26, 2021, 04:51 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 24, 2021 | Tax Payment (Shares) | $282.98 | 322 | 91,120 | 17,246 | Feb 25, 2021, 03:27 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 22, 2021 | Tax Payment (Shares) | $289.55 | 317 | 91,787 | 17,883 | Feb 24, 2021, 10:42 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 23, 2021 | Tax Payment (Shares) | $283.59 | 315 | 89,331 | 17,568 | Feb 24, 2021, 10:42 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Dec 01, 2020 | Gift | - | 310 | - | 11,046 | Feb 02, 2021, 11:46 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Jan 29, 2021 | Tax Payment (Shares) | $260.88 | 4,708 | 1,228,223 | 18,200 | Feb 02, 2021, 11:46 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Jun 17, 2020 | Gift | - | 285 | - | 11,356 | Nov 05, 2020, 11:46 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Nov 04, 2020 | Option/RSU Exercise | $123.73 | 6,739 | 833,841 | 18,095 | Nov 05, 2020, 11:46 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Nov 04, 2020 | Sale | $250.28 | 6,739 | 1,686,627 | 15,456 | Nov 05, 2020, 11:46 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 15, 2020 | Option/RSU Exercise | $80.48 | 6,350 | 511,045 | 25,405 | May 19, 2020, 04:18 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 15, 2020 | Sale | $168.26 | 15,418 | 2,594,171 | 14,886 | May 19, 2020, 04:18 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | May 18, 2020 | Sale | $174.65 | 350 | 61,128 | 9,637 | May 19, 2020, 04:18 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 26, 2020 | Tax Payment (Shares) | $162.46 | 303 | 49,225 | 19,055 | Feb 26, 2020, 12:22 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 23, 2020 | Tax Payment (Shares) | $173.64 | 315 | 54,697 | 19,680 | Feb 24, 2020, 12:31 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 24, 2020 | Tax Payment (Shares) | $173.64 | 322 | 55,912 | 19,358 | Feb 24, 2020, 12:31 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 22, 2020 | Tax Payment (Shares) | $173.64 | 317 | 55,044 | 19,995 | Feb 24, 2020, 12:31 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 07, 2020 | Tax Payment (Shares) | $159.07 | 3,846 | 611,783 | 20,312 | Feb 10, 2020, 03:52 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL INC | Joseph W. Laplume | EVP, Corp Strategy & Develop | Mar 08, 2019 | Sale | $138.23 | 1,666 | 230,295 | 14,879 | Mar 12, 2019, 08:00 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL INC | Joseph W. Laplume | EVP, Corp Strategy & Develop | Mar 08, 2019 | Sale | $138.01 | 5,770 | 796,337 | 20,649 | Mar 12, 2019, 07:58 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL INC | Joseph W. Laplume | EVP, Corp Strategy & Develop | Mar 08, 2019 | Option/RSU Exercise | $88.27 | 11,588 | 1,022,916 | 26,371 | Mar 12, 2019, 07:57 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL INC | Joseph W. Laplume | EVP, Corp Strategy & Develop | Mar 08, 2019 | Sale | $137.61 | 5,522 | 759,892 | 26,171 | Mar 12, 2019, 07:57 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL INC | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 26, 2019 | Tax Payment (Shares) | $145.31 | 304 | 44,174 | 14,939 | Feb 28, 2019, 09:39 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL INC | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 27, 2019 | Tax Payment (Shares) | $140.71 | 156 | 21,951 | 14,783 | Feb 28, 2019, 09:39 AM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL INC | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 23, 2019 | Tax Payment (Shares) | $144.67 | 316 | 45,716 | 15,565 | Feb 26, 2019, 02:50 PM |
| CRL | | CHARLES RIVER LABORATORIES INTERNATIONAL INC | Joseph W. Laplume | EVP, Corp Strategy & Develop | Feb 24, 2019 | Tax Payment (Shares) | $144.67 | 322 | 46,584 | 15,243 | Feb 26, 2019, 02:50 PM |
