| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Oct 13, 2017 | Tax Payment (Shares) | $143.04 | 1,744 | 249,462 | 148,811 | Oct 17, 2017, 05:39 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Oct 13, 2017 | Option/RSU Exercise | $21.92 | 11,384 | 249,537 | 150,555 | Oct 17, 2017, 05:39 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Sep 05, 2017 | Sale | $130.00 | 5,000 | 650,000 | 139,171 | Sep 06, 2017, 08:48 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Sep 05, 2017 | Option/RSU Exercise | $21.00 | 5,000 | 105,000 | 144,171 | Sep 06, 2017, 08:48 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Aug 08, 2017 | Option/RSU Exercise | $21.00 | 5,483 | 115,143 | 144,654 | Aug 10, 2017, 06:39 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Aug 08, 2017 | Sale | $125.00 | 5,483 | 685,375 | 139,171 | Aug 10, 2017, 06:39 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Jun 21, 2017 | Option/RSU Exercise | $21.00 | 4,666 | 97,986 | 143,837 | Jun 23, 2017, 04:16 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Jun 21, 2017 | Sale | $120.00 | 4,666 | 559,920 | 139,171 | Jun 23, 2017, 04:16 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Jun 09, 2017 | Option/RSU Exercise | $21.00 | 12,000 | 252,000 | 151,171 | Jun 09, 2017, 07:26 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Jun 09, 2017 | Sale | $114.87 | 12,000 | 1,378,440 | 139,171 | Jun 09, 2017, 07:26 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Mar 20, 2017 | Sale | $109.10 | 4,000 | 436,400 | 139,171 | Mar 21, 2017, 05:49 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Mar 08, 2017 | Option/RSU Exercise | $10.05 | 15,675 | 157,534 | 144,644 | Mar 10, 2017, 06:03 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Mar 08, 2017 | Sale | $107.06 | 4,000 | 428,240 | 128,969 | Mar 10, 2017, 06:03 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Mar 08, 2017 | Tax Payment (Shares) | $106.92 | 1,473 | 157,493 | 143,171 | Mar 10, 2017, 06:03 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Feb 15, 2017 | Tax Payment (Shares) | $104.28 | 4,304 | 448,821 | 120,379 | Feb 28, 2017, 06:26 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Feb 24, 2017 | Tax Payment (Shares) | $100.38 | 4,783 | 480,118 | 122,745 | Feb 28, 2017, 06:26 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Sep 22, 2016 | Sale | $117.34 | 3,000 | 352,020 | 122,664 | Sep 23, 2016, 04:19 PM |
| TECH | | BIO-TECHNE Corp | John L. Higgins | Director | Sep 08, 2016 | Sale | $109.83 | 1,700 | 186,716 | 1,359 | Sep 12, 2016, 05:27 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Mar 08, 2016 | Option/RSU Exercise | $21.00 | 6,000 | 126,000 | 125,664 | Mar 09, 2016, 06:26 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Mar 07, 2016 | Sale | $102.47 | 10,833 | 1,110,027 | 120,220 | Mar 09, 2016, 06:26 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Feb 15, 2016 | Tax Payment (Shares) | $85.97 | 2,492 | 214,237 | 130,497 | Feb 16, 2016, 07:34 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Aug 06, 2015 | Sale | $110.79 | 4,666 | 516,946 | 121,378 | Aug 07, 2015, 04:22 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | Chief Executive Officer | Jun 09, 2015 | Sale | $92.88 | 10,000 | 928,809 | 129,844 | Jun 11, 2015, 06:13 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Aug 15, 2014 | Buy | $54.97 | 1,000 | 54,970 | 120,099 | Aug 15, 2014, 02:51 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Feb 12, 2014 | Option/RSU Exercise | $9.96 | 16,875 | 168,075 | 127,974 | Feb 14, 2014, 08:04 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Feb 12, 2014 | Sale | $75.00 | 16,875 | 1,265,625 | 111,099 | Feb 14, 2014, 08:04 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Jan 16, 2014 | Sale | $64.00 | 15,000 | 960,000 | 102,099 | Jan 21, 2014, 08:04 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Jan 21, 2014 | Option/RSU Exercise | $21.00 | 9,000 | 189,000 | 111,099 | Jan 21, 2014, 08:04 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Oct 22, 2013 | Option/RSU Exercise | $16.14 | 10,518 | 169,763 | 117,099 | Oct 22, 2013, 08:05 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Oct 18, 2013 | Sale | $55.00 | 10,000 | 550,000 | 106,581 | Oct 22, 2013, 08:05 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Aug 16, 2013 | Sale | $42.85 | 10,000 | 428,500 | 110,025 | Aug 20, 2013, 06:44 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Aug 19, 2013 | Option/RSU Exercise | $16.14 | 6,556 | 105,814 | 116,581 | Aug 20, 2013, 06:44 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Dec 05, 2012 | Buy | $18.03 | 2,000 | 36,060 | 112,025 | Dec 05, 2012, 04:53 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Aug 13, 2012 | Buy | $16.39 | 500 | 8,195 | 110,025 | Aug 14, 2012, 07:19 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Jun 29, 2012 | Other Acquisition or Disposition | $10.12 | 1,250 | 12,654 | 109,525 | Jul 03, 2012, 05:47 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | May 04, 2012 | Buy | $12.04 | 1,000 | 12,040 | 108,275 | May 08, 2012, 01:54 PM |
| LGNDD | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Dec 30, 2011 | Other Acquisition or Disposition | $10.09 | 210 | 2,119 | 89,275 | Jan 06, 2012, 05:21 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Dec 31, 2010 | Other Acquisition or Disposition | $7.14 | 294 | 2,099 | 73,788 | Jul 26, 2011, 06:02 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | John L. Higgins | President & CEO | Jun 30, 2011 | Other Acquisition or Disposition | $7.64 | 277 | 2,116 | 89,065 | Jul 26, 2011, 06:02 PM |
