| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Aug 06, 2025 | Buy | $389.68 | 5,000 | 1,948,416 | 45,000 | Aug 07, 2025, 04:19 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Aug 01, 2024 | Option/RSU Exercise | $125.71 | 5,295 | 665,634 | 45,295 | Aug 02, 2024, 04:10 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Aug 01, 2024 | Sale | $508.00 | 5,295 | 2,689,860 | 40,000 | Aug 02, 2024, 04:10 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | May 22, 2024 | Sale | $448.00 | 7,073 | 3,168,704 | 40,000 | May 24, 2024, 04:13 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | May 22, 2024 | Option/RSU Exercise | $93.51 | 7,073 | 661,396 | 47,073 | May 24, 2024, 04:13 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 06, 2023 | Option/RSU Exercise | $127.54 | 11,250 | 1,434,825 | 51,250 | Nov 08, 2023, 04:11 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 06, 2023 | Sale | $385.00 | 11,250 | 4,331,250 | 40,000 | Nov 08, 2023, 04:11 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jul 17, 2023 | Option/RSU Exercise | $127.54 | 11,250 | 1,434,825 | 51,250 | Jul 18, 2023, 04:17 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jul 17, 2023 | Sale | $356.75 | 11,250 | 4,013,459 | 49,553 | Jul 18, 2023, 04:17 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Apr 12, 2023 | Option/RSU Exercise | $72.14 | 21,300 | 1,536,582 | 62,510 | Apr 14, 2023, 04:14 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Apr 12, 2023 | Sale | $326.73 | 21,300 | 6,959,422 | 59,593 | Apr 14, 2023, 04:14 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Apr 13, 2023 | Gift | - | 1,210 | - | 40,000 | Apr 14, 2023, 04:14 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jan 31, 2023 | Option/RSU Exercise | $72.14 | 1,200 | 86,568 | 42,410 | Feb 02, 2023, 04:14 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jan 31, 2023 | Sale | $325.01 | 1,200 | 390,012 | 41,210 | Feb 02, 2023, 04:14 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Aug 02, 2021 | Buy | $197.91 | 15,000 | 2,968,650 | 41,210 | Aug 04, 2021, 04:05 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 10, 2020 | Buy | $217.36 | 15,000 | 3,260,465 | 26,210 | Nov 12, 2020, 08:18 AM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | May 07, 2020 | Option/RSU Exercise | $70.55 | 45,000 | 3,174,525 | 56,210 | May 08, 2020, 04:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | May 07, 2020 | Sale | $269.80 | 45,000 | 12,140,805 | 53,610 | May 08, 2020, 04:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jan 31, 2020 | Sale | $227.99 | 20,000 | 4,559,830 | 29,510 | Feb 04, 2020, 04:15 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jan 31, 2020 | Option/RSU Exercise | $53.85 | 20,000 | 1,077,000 | 31,210 | Feb 04, 2020, 04:15 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Dec 28, 2018 | Gift | - | 10,000 | - | 13,011 | Jan 02, 2019, 04:58 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Dec 06, 2018 | Option/RSU Exercise | $34.24 | 10,000 | 342,400 | 23,011 | Dec 07, 2018, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jun 01, 2016 | Award/Grant | $0.01000 | 2,941 | 29 | 24,151 | Jun 03, 2016, 05:09 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Aug 04, 2015 | Option/RSU Exercise | $34.24 | 10,000 | 342,400 | 31,210 | Aug 05, 2015, 04:18 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Aug 04, 2015 | Sale | $140.13 | 10,000 | 1,401,300 | 21,210 | Aug 05, 2015, 04:18 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Mar 20, 2015 | Option/RSU Exercise | $29.89 | 10,000 | 298,900 | 31,210 | Mar 24, 2015, 06:04 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Mar 20, 2015 | Sale | $135.52 | 10,000 | 1,355,190 | 22,585 | Mar 24, 2015, 06:04 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Mar 18, 2015 | Sale | $130.13 | 10,000 | 1,301,300 | 21,210 | Mar 20, 2015, 04:19 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Mar 18, 2015 | Option/RSU Exercise | $29.89 | 10,000 | 298,900 | 31,210 | Mar 20, 2015, 04:19 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jan 20, 2015 | Option/RSU Exercise | $28.40 | 139 | 3,948 | 21,349 | Jan 22, 2015, 05:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jan 20, 2015 | Sale | $125.00 | 139 | 17,375 | 21,210 | Jan 22, 2015, 05:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jan 09, 2015 | Option/RSU Exercise | $28.40 | 9,861 | 280,052 | 31,071 | Jan 13, 2015, 04:17 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jan 09, 2015 | Sale | $125.04 | 9,861 | 1,233,019 | 21,210 | Jan 13, 2015, 04:17 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 28, 2014 | Option/RSU Exercise | $28.40 | 10,000 | 284,000 | 31,210 | Dec 01, 2014, 05:10 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 28, 2014 | Sale | $120.03 | 10,000 | 1,200,300 | 21,210 | Dec 01, 2014, 05:10 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 06, 2014 | Sale | $115.21 | 9,900 | 1,140,579 | 21,210 | Nov 07, 2014, 04:25 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 06, 2014 | Option/RSU Exercise | $29.84 | 9,900 | 295,416 | 31,110 | Nov 07, 2014, 04:25 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 04, 2014 | Sale | $113.59 | 10,000 | 1,135,942 | 28,910 | Nov 05, 2014, 05:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 05, 2014 | Option/RSU Exercise | $29.84 | 100 | 2,984 | 21,310 | Nov 05, 2014, 05:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 05, 2014 | Sale | $111.86 | 100 | 11,186 | 21,210 | Nov 05, 2014, 05:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 03, 2014 | Option/RSU Exercise | $34.32 | 20,000 | 686,400 | 41,210 | Nov 05, 2014, 05:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 03, 2014 | Sale | $112.13 | 20,000 | 2,242,667 | 23,894 | Nov 05, 2014, 05:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 04, 2014 | Option/RSU Exercise | $29.84 | 10,000 | 298,400 | 31,210 | Nov 05, 2014, 05:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Mar 21, 2014 | Sale | $74.59 | 8,700 | 648,976 | 27,460 | Mar 25, 2014, 04:10 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Feb 20, 2014 | Sale | $83.66 | 8,300 | 694,349 | 36,910 | Feb 24, 2014, 04:30 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jan 22, 2014 | Sale | $84.47 | 8,300 | 701,071 | 40,710 | Jan 23, 2014, 04:16 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Dec 23, 2013 | Sale | $73.02 | 8,300 | 606,085 | 47,710 | Dec 26, 2013, 04:12 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Nov 20, 2013 | Sale | $65.28 | 8,300 | 541,808 | 62,410 | Nov 21, 2013, 04:54 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Oct 24, 2013 | Sale | $77.06 | 8,300 | 639,586 | 68,910 | Oct 25, 2013, 04:10 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Sep 25, 2013 | Sale | $74.97 | 8,300 | 622,263 | 73,910 | Sep 26, 2013, 02:09 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Aug 29, 2013 | Sale | $77.19 | 8,300 | 640,664 | 86,320 | Sep 03, 2013, 04:29 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jul 24, 2013 | Sale | $85.50 | 8,300 | 709,621 | 91,310 | Jul 26, 2013, 04:22 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jun 21, 2013 | Sale | $75.93 | 8,300 | 630,247 | 103,510 | Jun 24, 2013, 04:40 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | May 22, 2013 | Sale | $79.77 | 8,300 | 662,116 | 110,410 | May 23, 2013, 04:14 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | May 14, 2013 | Sale | $81.15 | 60,000 | 4,869,000 | 112,910 | May 16, 2013, 04:57 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | May 06, 2013 | Sale | $77.22 | 8,300 | 640,917 | 179,910 | May 08, 2013, 04:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Jun 03, 2011 | Sale | $55.02 | 7,500 | 412,650 | 181,210 | Jun 06, 2011, 03:33 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | May 27, 2011 | Option/RSU Exercise | $44.47 | 7,500 | 333,525 | 188,710 | Jun 01, 2011, 03:55 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Bruce I. Sachs | Director | Apr 27, 2011 | Gift | - | 20,000 | - | 181,210 | May 03, 2011, 03:06 PM |
