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Insider Transactions by Orbimed Advisors LLC

Symbol CompanyOwnerRelationshipDateTransactionCost# SharesValue ($)Total SharesFiling
TORCresTORbio, Inc.Orbimed Advisors LLCDirectorJan 30, 2018Conversion-4,297,054-4,297,054Jan 30, 2018, 06:41 PM
TORCresTORbio, Inc.Orbimed Advisors LLCDirectorJan 30, 2018Buy$15.00533,3337,999,9954,830,387Jan 30, 2018, 06:41 PM
SYBXSYNLOGIC, INC.Orbimed Advisors LLCDirectorJan 26, 2018Award/Grant$9.75715,0006,971,2502,029,996Jan 30, 2018, 04:30 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJan 26, 2018Buy$14.9322,760339,8072,972,760Jan 30, 2018, 03:34 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJan 29, 2018Buy$14.9950,000749,5003,022,760Jan 30, 2018, 03:34 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJan 12, 2018Buy$14.5038,354556,1332,731,069Jan 24, 2018, 08:59 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJan 19, 2018Buy$14.9574,9311,120,2182,806,000Jan 24, 2018, 08:59 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJan 22, 2018Buy$14.9875,0001,123,5002,881,000Jan 24, 2018, 08:59 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJan 23, 2018Buy$14.994,36365,4012,885,363Jan 24, 2018, 08:59 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJan 24, 2018Buy$14.9164,637963,7382,950,000Jan 24, 2018, 08:59 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJan 12, 2018Buy$15.4028,446438,0682,692,715Jan 12, 2018, 05:29 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJan 10, 2018Buy$12.83170,3382,185,4372,622,569Jan 12, 2018, 05:29 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJan 11, 2018Buy$13.6541,700569,2052,664,269Jan 12, 2018, 05:29 PM
PIRSPIERIS PHARMACEUTICALS, INC.Orbimed Advisors LLC10% OwnerJan 03, 2018Sale$7.351,709,62012,565,7075,500,730Jan 04, 2018, 03:23 PM
PIRSPIERIS PHARMACEUTICALS, INC.Orbimed Advisors LLC10% OwnerDec 18, 2017Option/RSU Exercise$2.09147,635308,0527,340,465Dec 20, 2017, 05:12 PM
PIRSPIERIS PHARMACEUTICALS, INC.Orbimed Advisors LLC10% OwnerDec 18, 2017Sale$5.70147,635841,5197,194,222Dec 20, 2017, 05:12 PM
SCPHscPharmaceuticals Inc.Orbimed Advisors LLC10% OwnerNov 21, 2017Conversion-2,576,532-2,576,532Nov 21, 2017, 07:13 PM
SCPHscPharmaceuticals Inc.Orbimed Advisors LLC10% OwnerNov 21, 2017Buy$14.00833,33311,666,6623,409,865Nov 21, 2017, 07:13 PM
ASNSArsanis, Inc.Orbimed Advisors LLC10% OwnerNov 20, 2017Conversion$2.681,868,9665,000,0001,868,966Nov 20, 2017, 05:32 PM
RYTMRHYTHM PHARMACEUTICALS, INC.Orbimed Advisors LLC10% OwnerOct 10, 2017Conversion-2,546,295-2,546,295Oct 10, 2017, 04:21 PM
RYTMRHYTHM PHARMACEUTICALS, INC.Orbimed Advisors LLC10% OwnerOct 10, 2017Buy$17.00355,0006,035,0002,901,295Oct 10, 2017, 04:21 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorAug 31, 2017Sale$37.8244,9221,698,9501,358,833Sep 05, 2017, 09:27 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorSep 01, 2017Sale$37.72110,0784,152,1421,249,793Sep 05, 2017, 09:27 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorSep 05, 2017Sale$39.09425,20016,621,7301,076,444Sep 05, 2017, 09:27 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorAug 15, 2017Sale$38.2932,5001,244,4251,693,072Aug 17, 2017, 05:20 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorAug 16, 2017Sale$38.0165,5802,492,6961,628,111Aug 17, 2017, 05:20 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorAug 17, 2017Sale$37.85226,9208,588,9221,403,331Aug 17, 2017, 05:20 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJul 25, 2017Conversion-2,055,946-2,055,946Jul 27, 2017, 07:17 PM
KALAKala Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerJul 25, 2017Buy$15.00319,3334,789,9952,375,279Jul 27, 2017, 07:17 PM
ADAPAdaptimmune Therapeutics PLCOrbimed Advisors LLCDirectorMar 27, 2017Buy$4.201,190,4764,999,9996,149,377Mar 28, 2017, 06:48 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorMar 14, 2017Sale$44.5474,1003,300,4141,725,265Mar 14, 2017, 07:39 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorMar 10, 2017Sale$45.9897,0284,461,3472,008,071Mar 14, 2017, 07:39 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorMar 13, 2017Sale$45.30211,4109,577,4541,799,359Mar 14, 2017, 07:39 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorMar 03, 2017Sale$47.0555,7722,624,0732,104,184Mar 07, 2017, 06:48 PM
AGLEAeglea BioTherapeutics, Inc.Orbimed Advisors LLC10% OwnerFeb 16, 2017Buy$5.0430,500153,7201,390,724Feb 21, 2017, 05:58 PM
AGLEAeglea BioTherapeutics, Inc.Orbimed Advisors LLC10% OwnerFeb 17, 2017Buy$5.1971,800372,6421,462,524Feb 21, 2017, 05:58 PM
AGLEAeglea BioTherapeutics, Inc.Orbimed Advisors LLC10% OwnerFeb 21, 2017Buy$5.367,00037,5201,469,524Feb 21, 2017, 05:58 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorAug 10, 2016Sale$33.77117,9383,982,7662,332,779Aug 12, 2016, 08:35 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorAug 11, 2016Sale$33.63160,9005,411,0672,173,397Aug 12, 2016, 08:35 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorAug 12, 2016Sale$33.7214,100475,4522,159,430Aug 12, 2016, 08:35 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorAug 03, 2016Sale$30.59425,00013,000,7502,449,604Aug 05, 2016, 04:05 PM
SELBSELECTA BIOSCIENCES INCOrbimed Advisors LLCDirectorJun 27, 2016Buy$14.00550,0007,700,0001,825,415Jun 29, 2016, 08:55 PM
SELBSELECTA BIOSCIENCES INCOrbimed Advisors LLCDirectorJun 27, 2016Conversion-1,177,995-1,280,604Jun 29, 2016, 08:55 PM
SELBSELECTA BIOSCIENCES INCOrbimed Advisors LLCDirectorJun 27, 2016Conversion-1,177,995-1,280,604Jun 29, 2016, 04:49 PM
SELBSELECTA BIOSCIENCES INCOrbimed Advisors LLCDirectorJun 27, 2016Buy$14.00550,0007,700,0001,825,415Jun 29, 2016, 04:49 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorJun 23, 2016Buy$12.921001,2925,378,449Jun 27, 2016, 06:47 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorJun 24, 2016Buy$12.9990011,6915,379,349Jun 27, 2016, 06:47 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorJun 17, 2016Buy$12.4812,300153,5045,352,266Jun 21, 2016, 06:55 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorJun 21, 2016Buy$12.8726,083335,6885,378,349Jun 21, 2016, 06:55 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorJun 14, 2016Buy$12.7110,000127,1005,329,966Jun 16, 2016, 05:59 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorJun 15, 2016Buy$11.945,00059,7005,334,966Jun 16, 2016, 05:59 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorJun 16, 2016Buy$12.045,00060,2005,339,966Jun 16, 2016, 05:59 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorJun 10, 2016Buy$12.9820,000259,6005,319,966Jun 13, 2016, 05:18 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorJun 09, 2016Buy$12.9530,000388,5005,299,966Jun 13, 2016, 05:18 PM
ADAPAdaptimmune Therapeutics PLCOrbimed Advisors LLCDirectorMay 20, 2016Buy$10.042,40024,09628,043,404May 25, 2016, 06:41 PM
ADAPAdaptimmune Therapeutics PLCOrbimed Advisors LLCDirectorMay 23, 2016Buy$10.401,191,60012,392,64029,235,004May 25, 2016, 06:41 PM
ADAPAdaptimmune Therapeutics PLCOrbimed Advisors LLCDirectorMay 24, 2016Buy$10.48518,4005,432,83229,753,404May 25, 2016, 06:41 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorMay 20, 2016Buy$13.094,71661,7325,269,966May 24, 2016, 04:37 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorMay 18, 2016Buy$11.554,20048,5105,262,650May 20, 2016, 05:21 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorMay 19, 2016Buy$12.132,60031,5255,265,250May 20, 2016, 05:21 PM
NTLAIntellia Therapeutics, Inc.Orbimed Advisors LLCDirectorMay 11, 2016Conversion-2,412,180-2,412,180May 13, 2016, 04:58 PM
NTLAIntellia Therapeutics, Inc.Orbimed Advisors LLCDirectorMay 11, 2016Buy$18.00250,0004,500,0002,662,180May 13, 2016, 04:58 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorMar 29, 2016Buy$15.00550,0008,250,0005,258,450Mar 29, 2016, 12:21 PM
CRVSCorvus Pharmaceuticals, Inc.Orbimed Advisors LLCDirectorMar 29, 2016Conversion-4,708,450-4,708,450Mar 29, 2016, 12:21 PM
PIRSPIERIS PHARMACEUTICALS, INC.Orbimed Advisors LLCDirectorJul 06, 2015Buy$2.75500,0001,375,0007,194,222Jul 08, 2015, 05:46 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorJun 30, 2015Option/RSU Exercise-27,607-2,882,216Jun 30, 2015, 05:51 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorJun 30, 2015Conversion-2,882,064-2,854,870Jun 30, 2015, 05:51 PM
GKOSGLAUKOS CorpOrbimed Advisors LLCDirectorJun 30, 2015Tax Payment (Shares)$18.0011,734211,2122,870,593Jun 30, 2015, 05:51 PM
SUPNSUPERNUS PHARMACEUTICALS INCOrbimed Advisors LLC10% OwnerFeb 12, 2013Sale$7.52152,1831,144,6902,291,900Feb 14, 2013, 05:20 PM
SUPNSUPERNUS PHARMACEUTICALS INCOrbimed Advisors LLC10% OwnerFeb 13, 2013Sale$7.58150,0001,136,3552,183,000Feb 14, 2013, 05:20 PM
SUPNSUPERNUS PHARMACEUTICALS INCOrbimed Advisors LLC10% OwnerDec 17, 2012Sale$6.85197,8151,354,617100,000Dec 19, 2012, 09:42 PM
SUPNSUPERNUS PHARMACEUTICALS INCOrbimed Advisors LLC10% OwnerDec 18, 2012Sale$7.08100,000707,6700Dec 19, 2012, 09:42 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorSep 04, 2012Sale$14.43233,7003,372,992594,300Sep 05, 2012, 05:33 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorJul 27, 2012Sale$14.613,45650,4837,944Jul 30, 2012, 07:26 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorJul 27, 2012Sale$14.61362,8445,300,207825,756Jul 30, 2012, 07:26 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorJun 19, 2012Sale$12.915,90076,18511,400Jun 19, 2012, 07:31 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorJun 19, 2012Sale$12.91611,2007,892,2421,188,600Jun 19, 2012, 07:31 PM
SUPNSUPERNUS PHARMACEUTICALS INCOrbimed Advisors LLCDirectorMay 04, 2012Conversion-2,499,998-1,668,472May 08, 2012, 04:18 PM
SUPNSUPERNUS PHARMACEUTICALS INCOrbimed Advisors LLCDirectorMay 04, 2012Buy$5.001,100,0005,500,0002,402,600May 08, 2012, 04:18 PM
PCRXPacira Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerMar 09, 2012Sale$11.2537,000416,0872,509,400Mar 13, 2012, 06:43 PM
PCRXPacira Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerMar 12, 2012Sale$11.0363,100696,1072,446,700Mar 13, 2012, 06:43 PM
PCRXPacira Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerFeb 29, 2012Sale$10.863,00032,5842,546,100Feb 29, 2012, 09:52 PM
PCRXPacira Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerFeb 27, 2012Sale$11.0529,000320,3692,559,500Feb 29, 2012, 09:52 PM
PCRXPacira Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerFeb 28, 2012Sale$11.1210,100112,3162,549,200Feb 29, 2012, 09:52 PM
PCRXPacira Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerFeb 01, 2012Sale$11.0170,000770,4062,662,200Feb 03, 2012, 09:30 PM
PCRXPacira Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerFeb 02, 2012Sale$10.8523,300252,9172,638,400Feb 03, 2012, 09:30 PM
PCRXPacira Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerFeb 03, 2012Sale$10.7950,000539,5202,588,700Feb 03, 2012, 09:30 PM
PCRXPacira Pharmaceuticals, Inc.Orbimed Advisors LLC10% OwnerOct 31, 2011Sale$10.5397,4411,025,6352,732,387Nov 02, 2011, 08:04 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorApr 29, 2011Sale$16.011,00016,01017,600May 03, 2011, 07:26 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorApr 29, 2011Sale$16.0199,0001,584,9901,832,400May 03, 2011, 07:26 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorMay 02, 2011Sale$16.303004,89017,300May 03, 2011, 07:26 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorMay 02, 2011Sale$16.3032,600531,3801,799,800May 03, 2011, 07:26 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorApr 20, 2011Sale$15.797,600120,00425,700Apr 26, 2011, 08:21 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorApr 20, 2011Sale$15.79792,40012,511,9962,674,300Apr 26, 2011, 08:21 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorApr 21, 2011Sale$16.67742,90012,381,6672,426,667Apr 25, 2011, 09:46 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorApr 21, 2011Sale$16.677,100118,33323,333Apr 25, 2011, 09:46 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorApr 18, 2011Sale$15.1828,200428,16844,832Apr 20, 2011, 09:39 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorApr 18, 2011Sale$15.182,971,80045,121,7294,682,029Apr 20, 2011, 09:39 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorApr 20, 2011Sale$15.79800,00012,632,0002,674,300Apr 20, 2011, 09:39 PM
AMRNAMARIN CORP PLCUKOrbimed Advisors LLCDirectorMar 28, 2011Sale$7.3592,200677,6706,438,500Mar 28, 2011, 09:41 PM

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