| Symbol | Company | Owner | Relationship | Date | Transaction | Cost | # Shares | Value ($) | Total Shares | Filing | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| STTK | Shattuck Labs, Inc. | Orbimed Advisors LLC | Director | Aug 25, 2025 | Buy | $0.87 | 6,306,127 | 5,471,826 | 5,255,106 | Sep 02, 2025, 09:52 PM | |
| IKNA | ImageneBio, Inc. | Orbimed Advisors LLC | Director | Jul 25, 2025 | Award/Grant | $2.49 | 83,611 | 208,191 | 287,885 | Jul 30, 2025, 09:30 PM | |
| CRVS | Corvus Pharmaceuticals, Inc. | Orbimed Advisors LLC | Director | Jun 27, 2025 | Sale | $4.16 | 1,176,332 | 4,891,894 | 7,165,006 | Jul 01, 2025, 09:23 PM | |
| CRVS | Corvus Pharmaceuticals, Inc. | Orbimed Advisors LLC | Director | Jun 27, 2025 | ATM/ITM Option Exercise | $3.50 | 1,397,684 | 4,891,894 | 8,341,338 | Jul 01, 2025, 09:23 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jun 24, 2025 | Sale | $0.35 | 231,600 | 81,060 | 6,418,400 | Jun 26, 2025, 05:10 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jun 25, 2025 | Sale | $0.33 | 138,800 | 45,804 | 6,279,600 | Jun 26, 2025, 05:10 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jun 26, 2025 | Sale | $0.33 | 213,257 | 70,375 | 6,066,343 | Jun 26, 2025, 05:10 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | May 14, 2025 | Sale | $15.85 | 168,136 | 2,665,333 | 3,272,199 | May 16, 2025, 05:26 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Apr 24, 2025 | Sale | $0.32 | 68,195 | 21,822 | 6,650,000 | Apr 24, 2025, 05:38 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Apr 22, 2025 | Sale | $0.34 | 78,049 | 26,537 | 6,807,523 | Apr 24, 2025, 05:38 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Apr 23, 2025 | Sale | $0.34 | 89,328 | 30,372 | 6,718,195 | Apr 24, 2025, 05:38 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Apr 15, 2025 | Sale | $0.38 | 10,326 | 3,924 | 7,024,300 | Apr 17, 2025, 06:10 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Apr 16, 2025 | Sale | $0.33 | 61,638 | 20,341 | 6,962,662 | Apr 17, 2025, 06:10 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Apr 17, 2025 | Sale | $0.33 | 77,090 | 25,440 | 6,885,572 | Apr 17, 2025, 06:10 PM | |
| XTNT | Xtant Medical Holdings, Inc. | Orbimed Advisors LLC | 10% Owner | Apr 10, 2025 | Sale | $0.42 | 73,114,592 | 30,708,128 | 0 | Apr 14, 2025, 07:14 PM | |
| CMPX | Compass Therapeutics, Inc. | Orbimed Advisors LLC | Director | Apr 09, 2025 | Sale | $1.59 | 3,571,428 | 5,678,571 | 0 | Apr 11, 2025, 07:24 PM | |
| EWTX | Edgewise Therapeutics, Inc. | Orbimed Advisors LLC | Director | Apr 03, 2025 | Buy | $20.13 | 496,771 | 10,000,000 | 14,809,075 | Apr 04, 2025, 07:33 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Mar 24, 2025 | Sale | $54.11 | 5,738 | 310,483 | 746,171 | Mar 26, 2025, 07:00 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Mar 20, 2025 | Sale | $54.01 | 2,762 | 149,176 | 754,476 | Mar 21, 2025, 08:00 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Mar 21, 2025 | Sale | $54.00 | 10,011 | 540,594 | 749,197 | Mar 21, 2025, 08:00 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Mar 19, 2025 | Sale | $54.02 | 39,656 | 2,142,217 | 755,933 | Mar 21, 2025, 08:00 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Mar 10, 2025 | Sale | $54.29 | 202,146 | 10,974,795 | 835,185 | Mar 12, 2025, 09:34 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Mar 11, 2025 | Sale | $54.01 | 27,056 | 1,461,295 | 820,707 | Mar 12, 2025, 09:34 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Mar 12, 2025 | Sale | $54.45 | 83,182 | 4,529,507 | 819,774 | Mar 12, 2025, 09:34 PM | |
| MBX | MBX Biosciences, Inc. | Orbimed Advisors LLC | Director | Feb 18, 2025 | Buy | $10.84 | 143,170 | 1,551,963 | 3,255,000 | Feb 19, 2025, 05:52 PM | |
| MBX | MBX Biosciences, Inc. | Orbimed Advisors LLC | Director | Feb 14, 2025 | Buy | $9.87 | 47,502 | 468,793 | 3,205,930 | Feb 19, 2025, 05:52 PM | |
| SION | Sionna Therapeutics, Inc. | Orbimed Advisors LLC | Director | Feb 10, 2025 | Conversion | - | 3,154,959 | - | 3,154,959 | Feb 10, 2025, 04:28 PM | |
| SION | Sionna Therapeutics, Inc. | Orbimed Advisors LLC | Director | Feb 10, 2025 | Buy | $18.00 | 550,000 | 9,900,000 | 3,704,959 | Feb 10, 2025, 04:28 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jan 10, 2025 | Sale | $0.66 | 126,209 | 83,298 | 7,131,636 | Jan 14, 2025, 05:17 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jan 13, 2025 | Sale | $0.64 | 17,986 | 11,511 | 7,113,650 | Jan 14, 2025, 05:17 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jan 14, 2025 | Sale | $0.60 | 79,024 | 47,414 | 7,034,626 | Jan 14, 2025, 05:17 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jan 06, 2025 | Sale | $0.77 | 19,481 | 15,000 | 7,385,388 | Jan 08, 2025, 06:09 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jan 07, 2025 | Sale | $0.71 | 52,536 | 37,301 | 7,332,852 | Jan 08, 2025, 06:09 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jan 08, 2025 | Sale | $0.68 | 75,007 | 51,005 | 7,257,845 | Jan 08, 2025, 06:09 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Dec 20, 2024 | Sale | $0.60 | 230,321 | 138,193 | 7,404,869 | Dec 26, 2024, 04:34 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Dec 11, 2024 | Sale | $0.80 | 80 | 64 | 7,635,190 | Dec 11, 2024, 05:32 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Dec 09, 2024 | Sale | $0.84 | 54,181 | 45,512 | 7,643,285 | Dec 11, 2024, 05:32 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Dec 10, 2024 | Sale | $0.80 | 8,015 | 6,412 | 7,635,270 | Dec 11, 2024, 05:32 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Dec 04, 2024 | Sale | $0.79 | 76,200 | 60,198 | 7,718,369 | Dec 06, 2024, 07:07 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Dec 06, 2024 | Sale | $0.82 | 20,903 | 17,140 | 7,697,466 | Dec 06, 2024, 07:07 PM | |
| UPB | Upstream Bio, Inc. | Orbimed Advisors LLC | Director | Oct 15, 2024 | Buy | $17.00 | 825,000 | 14,025,000 | 4,554,873 | Oct 17, 2024, 04:17 PM | |
| UPB | Upstream Bio, Inc. | Orbimed Advisors LLC | Director | Oct 15, 2024 | Conversion | - | 3,609,789 | - | 3,894,873 | Oct 17, 2024, 04:17 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Sep 19, 2024 | Sale | $0.71 | 39,300 | 27,903 | 7,794,569 | Sep 23, 2024, 04:51 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Sep 16, 2024 | Sale | $0.74 | 63,100 | 46,694 | 7,970,900 | Sep 18, 2024, 06:38 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Sep 17, 2024 | Sale | $0.73 | 111,400 | 81,322 | 7,859,500 | Sep 18, 2024, 06:38 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Sep 18, 2024 | Sale | $0.73 | 25,631 | 18,711 | 7,833,869 | Sep 18, 2024, 06:38 PM | |
| MBX | MBX Biosciences, Inc. | Orbimed Advisors LLC | Director | Sep 16, 2024 | Conversion | - | 403,787 | - | 403,787 | Sep 17, 2024, 08:13 PM | |
| MBX | MBX Biosciences, Inc. | Orbimed Advisors LLC | Director | Sep 16, 2024 | Buy | $16.00 | 250,000 | 4,000,000 | 653,787 | Sep 17, 2024, 08:13 PM | |
| MBX | MBX Biosciences, Inc. | Orbimed Advisors LLC | Director | Sep 16, 2024 | Conversion | - | 2,658,428 | - | 2,658,428 | Sep 17, 2024, 08:13 PM | |
| MBX | MBX Biosciences, Inc. | Orbimed Advisors LLC | Director | Sep 16, 2024 | Buy | $16.00 | 500,000 | 8,000,000 | 3,158,428 | Sep 17, 2024, 08:13 PM | |
| SPRY | ARS Pharmaceuticals, Inc. | Orbimed Advisors LLC | Director | Aug 26, 2024 | Sale | $13.00 | 83,695 | 1,088,035 | 0 | Aug 28, 2024, 04:26 PM | |
| SPRY | ARS Pharmaceuticals, Inc. | Orbimed Advisors LLC | Director | Aug 21, 2024 | Sale | $13.56 | 407,700 | 5,526,601 | 557,977 | Aug 23, 2024, 06:38 PM | |
| SPRY | ARS Pharmaceuticals, Inc. | Orbimed Advisors LLC | Director | Aug 22, 2024 | Sale | $12.94 | 391,482 | 5,065,777 | 153,195 | Aug 23, 2024, 06:38 PM | |
| SPRY | ARS Pharmaceuticals, Inc. | Orbimed Advisors LLC | Director | Aug 23, 2024 | Sale | $13.03 | 69,500 | 905,585 | 83,695 | Aug 23, 2024, 06:38 PM | |
| KROS | Keros Therapeutics, Inc. | Orbimed Advisors LLC | Director | Aug 13, 2024 | Sale | $44.01 | 250,000 | 11,002,500 | 899,212 | Aug 15, 2024, 05:01 PM | |
| SCPH | scPharmaceuticals Inc. | Orbimed Advisors LLC | 10% Owner | Aug 13, 2024 | Buy | $4.00 | 500,000 | 2,000,000 | 5,806,670 | Aug 15, 2024, 04:51 PM | |
| TERN | Terns Pharmaceuticals, Inc. | Orbimed Advisors LLC | Director | Jul 16, 2024 | Sale | $10.00 | 5,188 | 51,880 | 4,839,412 | Jul 17, 2024, 08:48 PM | |
| TERN | Terns Pharmaceuticals, Inc. | Orbimed Advisors LLC | Director | Jul 15, 2024 | Sale | $10.00 | 50,976 | 509,760 | 4,843,421 | Jul 17, 2024, 08:48 PM | |
| TELA | TELA Bio, Inc. | Orbimed Advisors LLC | 10% Owner | Jun 28, 2024 | Sale | $4.74 | 378,000 | 1,791,720 | 2,457,542 | Jul 02, 2024, 04:54 PM | |
| TELA | TELA Bio, Inc. | Orbimed Advisors LLC | 10% Owner | Jul 01, 2024 | Sale | $4.68 | 13,700 | 64,116 | 2,443,842 | Jul 02, 2024, 04:54 PM | |
| TELA | TELA Bio, Inc. | Orbimed Advisors LLC | 10% Owner | Jul 02, 2024 | Sale | $4.54 | 36,600 | 166,164 | 2,407,242 | Jul 02, 2024, 04:54 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Jun 17, 2024 | Buy | $36.00 | 83,334 | 3,000,024 | 941,569 | Jun 20, 2024, 05:19 PM | |
| ELVN | Enliven Therapeutics, Inc. | Orbimed Advisors LLC | Director | May 16, 2024 | Sale | $22.14 | 1,033,300 | 22,877,261 | 7,663,349 | May 20, 2024, 05:00 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | May 01, 2024 | Sale | $14.02 | 15,690 | 219,974 | 3,419,851 | May 03, 2024, 05:16 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | May 02, 2024 | Sale | $14.01 | 8,842 | 123,876 | 3,411,009 | May 03, 2024, 05:16 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | May 03, 2024 | Sale | $14.03 | 4,674 | 65,576 | 3,406,335 | May 03, 2024, 05:16 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Apr 24, 2024 | Sale | $14.06 | 1,781 | 25,041 | 3,435,541 | Apr 26, 2024, 05:01 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Apr 19, 2024 | Sale | $14.02 | 18,253 | 255,907 | 3,483,722 | Apr 23, 2024, 06:38 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Apr 22, 2024 | Sale | $14.05 | 24,609 | 345,756 | 3,459,113 | Apr 23, 2024, 06:38 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Apr 23, 2024 | Sale | $14.29 | 21,791 | 311,393 | 3,437,322 | Apr 23, 2024, 06:38 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Apr 16, 2024 | Sale | $14.01 | 14,069 | 197,107 | 3,504,898 | Apr 18, 2024, 05:10 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Apr 17, 2024 | Sale | $14.15 | 300 | 4,245 | 3,504,598 | Apr 18, 2024, 05:10 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Apr 18, 2024 | Sale | $14.06 | 2,623 | 36,879 | 3,501,975 | Apr 18, 2024, 05:10 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Apr 11, 2024 | Sale | $14.49 | 461,899 | 6,692,916 | 3,542,068 | Apr 15, 2024, 05:25 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Apr 12, 2024 | Sale | $14.42 | 23,101 | 333,116 | 3,518,967 | Apr 15, 2024, 05:25 PM | |
| AVBP | ArriVent Biopharma, Inc. | Orbimed Advisors LLC | Director | Jan 30, 2024 | Conversion | - | 2,582,884 | - | 1,291,442 | Jan 31, 2024, 04:12 PM | |
| AVBP | ArriVent Biopharma, Inc. | Orbimed Advisors LLC | Director | Jan 30, 2024 | Buy | $18.00 | 444,444 | 7,999,992 | 1,513,664 | Jan 31, 2024, 04:12 PM | |
| ACET | Adicet Bio, Inc. | Orbimed Advisors LLC | Director | Jan 25, 2024 | Buy | $2.40 | 3,125,000 | 7,500,000 | 7,526,359 | Jan 26, 2024, 07:14 PM | |
| EWTX | Edgewise Therapeutics, Inc. | Orbimed Advisors LLC | Director | Jan 23, 2024 | Buy | $11.00 | 454,545 | 4,999,995 | 14,436,497 | Jan 25, 2024, 04:28 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Dec 18, 2023 | Option/RSU Exercise | $38.00 | 1,724 | 65,512 | 1,724 | Dec 20, 2023, 06:28 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Dec 18, 2023 | Sale | $59.24 | 1,724 | 102,130 | 0 | Dec 20, 2023, 06:28 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Dec 14, 2023 | Sale | $56.75 | 433,200 | 24,584,100 | 897,625 | Dec 15, 2023, 06:04 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Dec 14, 2023 | Sale | $57.73 | 200 | 11,546 | 1,126,125 | Dec 14, 2023, 05:44 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Dec 12, 2023 | Sale | $60.16 | 27,300 | 1,642,368 | 1,182,425 | Dec 14, 2023, 05:44 PM | |
| IRON | Disc Medicine, Inc. | Orbimed Advisors LLC | Director | Dec 13, 2023 | Sale | $58.56 | 106,700 | 6,248,352 | 1,126,225 | Dec 14, 2023, 05:44 PM | |
| PMVP | PMV Pharmaceuticals, Inc. | Orbimed Advisors LLC | 10% Owner | Nov 22, 2023 | Sale | $2.23 | 87,786 | 195,763 | 0 | Nov 24, 2023, 04:38 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Oct 02, 2023 | Sale | $9.08 | 7,614 | 69,135 | 4,004,667 | Oct 04, 2023, 05:36 PM | |
| NPCE | NeuroPace Inc | Orbimed Advisors LLC | 10% Owner | Oct 03, 2023 | Sale | $9.02 | 700 | 6,314 | 4,003,967 | Oct 04, 2023, 05:36 PM | |
| SPRY | ARS Pharmaceuticals, Inc. | Orbimed Advisors LLC | Director | Aug 29, 2023 | Buy | $6.20 | 500,000 | 3,100,000 | 8,019,187 | Aug 31, 2023, 05:26 PM | |
| GLTO | Galecto, Inc. | Orbimed Advisors LLC | 10% Owner | Aug 15, 2023 | Sale | $0.75 | 822,680 | 617,010 | 1,510,375 | Aug 17, 2023, 04:40 PM | |
| GLTO | Galecto, Inc. | Orbimed Advisors LLC | 10% Owner | Jul 31, 2023 | Sale | $3.00 | 209,400 | 628,200 | 2,105,909 | Aug 02, 2023, 05:05 PM | |
| GLTO | Galecto, Inc. | Orbimed Advisors LLC | 10% Owner | Jul 25, 2023 | Sale | $2.92 | 39,200 | 114,464 | 2,258,987 | Jul 27, 2023, 04:28 PM | |
| GLTO | Galecto, Inc. | Orbimed Advisors LLC | 10% Owner | Jul 13, 2023 | Sale | $2.40 | 194,700 | 467,280 | 2,285,687 | Jul 17, 2023, 04:13 PM | |
| ACET | Adicet Bio, Inc. | Orbimed Advisors LLC | Director | Jun 27, 2023 | Buy | $2.09 | 875,000 | 1,828,750 | 5,685,259 | Jun 29, 2023, 04:46 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jun 27, 2023 | Buy | $0.84 | 617,382 | 518,601 | 7,458,805 | Jun 29, 2023, 04:42 PM | |
| PASG | Passage BIO, Inc. | Orbimed Advisors LLC | 10% Owner | Jun 28, 2023 | Buy | $0.84 | 575,195 | 483,164 | 8,034,000 | Jun 29, 2023, 04:42 PM | |
| PRLD | Prelude Therapeutics Inc | Orbimed Advisors LLC | Director | May 22, 2023 | Buy | $5.75 | 869,565 | 4,999,999 | 10,119,756 | May 24, 2023, 05:09 PM | |
| ELVN | Enliven Therapeutics, Inc. | Orbimed Advisors LLC | Director | May 17, 2023 | Option/RSU Exercise | $4.28 | 2,125 | 9,095 | 8,663,349 | May 19, 2023, 04:19 PM | |
| VRNA | Verona Pharma plc | Orbimed Advisors LLC | Director | May 15, 2023 | Sale | $20.08 | 359,713 | 7,222,484 | 4,123,091 | May 15, 2023, 06:07 PM | |
| VRNA | Verona Pharma plc | Orbimed Advisors LLC | Director | May 11, 2023 | Sale | $22.26 | 80,000 | 1,780,800 | 4,180,691 | May 15, 2023, 06:07 PM |