| SPY | SPDR S&P 500 ETF TR (Put) | 13.04% | 700,000 | $432,495,000 | 300,000 | 75% | $617.85 | 13F |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 4.88% | 11,535,582 | $161,728,860 | 112,604 | 0.99% | $14.02 | 13F |
| IWM | ISHARES TR (Put) | 4.57% | 702,500 | $151,592,475 | 702,500 | New | $215.79 | 13F |
| ETNB | 89BIO INC | 4.21% | 14,210,000 | $139,542,200 | -125,244 | -0.87% | $9.82 | 13F |
| LEGN | LEGEND BIOTECH CORP | 4.04% | 3,774,009 | $133,939,579 | 24,044 | 0.64% | $35.49 | 13F |
| META | META PLATFORMS INC | 3.78% | 169,845 | $125,360,896 | -9,819 | -5.47% | $738.09 | 13F |
| BNTC | BENITEC BIOPHARMA INC | 3.48% | 9,876,506 | $115,555,120 | | No Change | $11.7 | 13F |
| KO | COCA COLA CO | 2.63% | 1,233,230 | $87,251,023 | 817,510 | 196.65% | $70.75 | 13F |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 2.5% | 2,278,000 | $82,828,080 | 253,500 | 12.52% | $36.36 | 13F |
| GE | GE AEROSPACE | 2.41% | 310,262 | $79,858,336 | 109,600 | 54.62% | $257.39 | 13F |
| BHVN | BIOHAVEN LTD | 2.39% | 5,620,271 | $79,302,024 | | No Change | $14.11 | 13F |
| NVDA | NVIDIA CORPORATION | 2.38% | 499,562 | $78,925,800 | 146,797 | 41.61% | $157.99 | 13F |
| NVDA | NVIDIA CORPORATION (Call) | 2.38% | 500,000 | $78,995,000 | 500,000 | New | $157.99 | 13F |
| AVBP | ARRIVENT BIOPHARMA INC | 2.24% | 3,412,788 | $74,296,395 | 1,075,292 | 46% | $21.77 | 13F |
| TSM | TAIWAN SEMICONDUCTOR MFG LTD | 2.05% | 300,401 | $68,037,822 | -50,113 | -14.3% | $226.49 | 13F |
| IMTX | IMMATICS N.V | 1.95% | 12,030,129 | $64,722,094 | 2,895,100 | 31.69% | $5.38 | 13F |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 1.93% | 6,804,091 | $64,026,496 | | No Change | $9.41 | 13F |
| APO | APOLLO GLOBAL MGMT INC | 1.83% | 428,460 | $60,785,620 | 31,920 | 8.05% | $141.87 | 13F |
| AMD | ADVANCED MICRO DEVICES INC | 1.71% | 398,799 | $56,589,578 | -5,209 | -1.29% | $141.9 | 13F |
| AMZN | AMAZON COM INC | 1.7% | 257,625 | $56,520,349 | -96,731 | -27.3% | $219.39 | 13F |
| KALV | KALVISTA PHARMACEUTICALS INC | 1.69% | 4,955,000 | $56,016,275 | 41,988 | 0.85% | $11.31 | 13F |
| DKS | DICKS SPORTING GOODS INC | 1.55% | 260,465 | $51,522,582 | 260,465 | New | $197.81 | 13F |
| ORCL | ORACLE CORP | 1.52% | 230,728 | $50,444,063 | 4,410 | 1.95% | $218.63 | 13F |
| APLS | APELLIS PHARMACEUTICALS INC | 1.5% | 2,878,000 | $49,818,180 | 1,231,385 | 74.78% | $17.31 | 13F |
| MSFT | MICROSOFT CORP | 1.48% | 98,828 | $49,158,035 | -81,297 | -45.13% | $497.41 | 13F |
| HD | HOME DEPOT INC | 1.44% | 130,721 | $47,927,547 | 33,150 | 33.98% | $366.64 | 13F |
| KURA | KURA ONCOLOGY INC | 1.41% | 8,116,000 | $46,829,320 | 676,741 | 9.1% | $5.77 | 13F |
| BAC | BANK AMERICA CORP | 1.32% | 927,190 | $43,874,631 | 173,277 | 22.98% | $47.32 | 13F |
| COF | CAPITAL ONE FINL CORP | 1.25% | 194,160 | $41,309,482 | -51,062 | -20.82% | $212.76 | 13F |
| FERG | FERGUSON ENTERPRISES INC | 1.24% | 189,660 | $41,298,465 | 59,736 | 45.98% | $217.75 | 13F |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 1.19% | 532,280 | $39,425,980 | 532,280 | New | $74.07 | 13F |
| BSX | BOSTON SCIENTIFIC CORP | 1.14% | 353,561 | $37,975,987 | 91,462 | 34.9% | $107.41 | 13F |
| FULC | FULCRUM THERAPEUTICS INC | 1.05% | 5,082,900 | $34,970,352 | 15,506 | 0.31% | $6.88 | 13F |
| DHR | DANAHER CORPORATION | 1.04% | 174,700 | $34,510,238 | 161,100 | 1184.56% | $197.54 | 13F |
| RCUS | ARCUS BIOSCIENCES INC | 0.91% | 3,688,858 | $30,027,304 | 1,127,954 | 44.05% | $8.14 | 13F |
| TSLA | TESLA INC | 0.88% | 92,357 | $29,338,125 | -29,659 | -24.31% | $317.66 | 13F |
| AURA | AURA BIOSCIENCES INC | 0.83% | 4,372,884 | $27,374,254 | 1,640,998 | 60.07% | $6.26 | 13F |
| DDOG | DATADOG INC | 0.72% | 178,832 | $24,022,503 | -4,399 | -2.4% | $134.33 | 13F |
| INSM | INSMED INC | 0.72% | 238,783 | $24,031,121 | -1,253,600 | -84% | $100.64 | 13F |
| MLYS | MINERALYS THERAPEUTICS INC | 0.71% | 1,744,492 | $23,602,977 | 76,733 | 4.6% | $13.53 | 13F |
| UNH | UNITEDHEALTH GROUP INC | 0.64% | 68,000 | $21,213,960 | 38,100 | 127.42% | $311.97 | 13F |
| JNJ | JOHNSON & JOHNSON | 0.61% | 132,786 | $20,283,062 | 23,400 | 21.39% | $152.75 | 13F |
| BIIB | BIOGEN INC | 0.58% | 151,890 | $19,075,865 | 31,154 | 25.8% | $125.59 | 13F |
| CMPX | COMPASS THERAPEUTICS INC | 0.56% | 7,149,493 | $18,588,682 | 7,149,493 | New | $2.6 | 13F |
| ERAS | ERASCA INC | 0.56% | 14,502,004 | $18,417,545 | 2,187,000 | 17.76% | $1.27 | 13F |
| MRK | MERCK & CO INC | 0.52% | 219,178 | $17,350,130 | 75,078 | 52.1% | $79.16 | 13F |
| GS | GOLDMAN SACHS GROUP INC | 0.51% | 24,108 | $17,062,437 | -1,430 | -5.6% | $707.75 | 13F |
| PVLA | PALVELLA THERAPEUTICS INC NE | 0.49% | 714,463 | $16,103,996 | | No Change | $22.54 | 13F |
| ABEO | ABEONA THERAPEUTICS INC | 0.46% | 2,676,000 | $15,199,680 | -1,009,503 | -27.39% | $5.68 | 13F |
| GLUE | MONTE ROSA THERAPEUTICS INC | 0.46% | 3,360,000 | $15,153,600 | 1,796,202 | 114.86% | $4.51 | 13F |
| PINS | PINTEREST INC | 0.46% | 430,025 | $15,420,697 | 430,025 | New | $35.86 | 13F |
| MRNA | MODERNA INC | 0.43% | 517,163 | $14,268,527 | | No Change | $27.59 | 13F |
| KYMR | KYMERA THERAPEUTICS INC | 0.36% | 275,000 | $12,001,000 | 275,000 | New | $43.64 | 13F |
| RCKT | ROCKET PHARMACEUTICALS INC | 0.31% | 4,143,333 | $10,151,166 | 641,333 | 18.31% | $2.45 | 13F |
| MOLN | MOLECULAR PARTNERS AG | 0.26% | 2,221,494 | $8,486,107 | | No Change | $3.82 | 13F |
| TSHA | TAYSHA GENE THERAPIES INC | 0.22% | 3,217,449 | $7,432,307 | 3,217,449 | New | $2.31 | 13F |
| PROK | PROKIDNEY CORP | 0.22% | 12,341,266 | $7,307,264 | | No Change | $0.59 | 13F |
| WHWK | WHITEHAWK THERAPEUTICS INC | 0.21% | 3,700,000 | $6,919,000 | | No Change | $1.87 | 13F |
| CTNM | CONTINEUM THERAPEUTICS INC | 0.21% | 1,720,000 | $6,828,400 | | No Change | $3.97 | 13F |
| ABT | ABBOTT LABS | 0.17% | 40,520 | $5,511,125 | -18,300 | -31.11% | $136.01 | 13F |
| EXAS | EXACT SCIENCES CORP | 0.15% | 94,100 | $5,000,474 | | No Change | $53.14 | 13F |
| ZURA | ZURA BIO LTD | 0.15% | 4,860,939 | $5,103,986 | | No Change | $1.05 | 13F |
| IFRX | INFLARX NV | 0.15% | 6,483,910 | $5,122,289 | | No Change | $0.79 | 13F |
| REGN | REGENERON PHARMACEUTICALS | 0.14% | 8,630 | $4,530,750 | 8,630 | New | $525 | 13F |
| STRO | SUTRO BIOPHARMA INC | 0.14% | 6,488,324 | $4,632,015 | -974,171 | -13.05% | $0.71 | 13F |
| COR | CENCORA INC | 0.11% | 12,488 | $3,744,527 | | No Change | $299.85 | 13F |
| ELAN | ELANCO ANIMAL HEALTH INC | 0.11% | 253,600 | $3,621,408 | | No Change | $14.28 | 13F |
| KZR | KEZAR LIFE SCIENCES INC | 0.1% | 716,759 | $3,282,756 | | No Change | $4.58 | 13F |
| TMO | THERMO FISHER SCIENTIFIC INC | 0.1% | 7,900 | $3,203,134 | | No Change | $405.46 | 13F |
| ISRG | INTUITIVE SURGICAL INC | 0.09% | 5,200 | $2,825,732 | | No Change | $543.41 | 13F |
| DXCM | DEXCOM INC | 0.08% | 31,680 | $2,765,347 | | No Change | $87.29 | 13F |
| MTD | METTLER TOLEDO INTERNATIONAL | 0.07% | 1,964 | $2,307,150 | | No Change | $1174.72 | 13F |
| SYK | STRYKER CORPORATION | 0.07% | 5,860 | $2,318,392 | | No Change | $395.63 | 13F |
| MDT | MEDTRONIC PLC | 0.07% | 25,060 | $2,184,480 | | No Change | $87.17 | 13F |
| NTRA | NATERA INC | 0.05% | 10,100 | $1,706,294 | | No Change | $168.94 | 13F |
| HCA | HCA HEALTHCARE INC | 0.04% | 3,190 | $1,222,089 | | No Change | $383.1 | 13F |
| MCK | MCKESSON CORP | 0.04% | 1,830 | $1,340,987 | | No Change | $732.78 | 13F |
| WING | WINGSTOP INC | 0.04% | 3,961 | $1,333,827 | 3,961 | New | $336.74 | 13F |
| AVTR | AVANTOR INC | 0.03% | 71,850 | $967,101 | | No Change | $13.46 | 13F |
| GLPG | GALAPAGOS NV | 0.03% | 37,111 | $1,038,737 | | No Change | $27.99 | 13F |
| IQV | IQVIA HLDGS INC | 0.03% | 7,175 | $1,130,708 | | No Change | $157.59 | 13F |
| OS | ONESTREAM INC | 0.03% | 33,080 | $936,164 | 33,080 | New | $28.3 | 13F |
| WAT | WATERS CORP | 0.03% | 3,150 | $1,099,476 | | No Change | $349.04 | 13F |
| EW | EDWARDS LIFESCIENCES CORP | 0.03% | 11,100 | $868,131 | | No Change | $78.21 | 13F |
| A | AGILENT TECHNOLOGIES INC | 0.02% | 4,990 | $588,870 | | No Change | $118.01 | 13F |
| CZR | CAESARS ENTERTAINMENT INC NE | 0.02% | 18,875 | $535,861 | -633,618 | -97.11% | $28.39 | 13F |
| RMD | RESMED INC | 0.02% | 2,390 | $616,620 | | No Change | $258 | 13F |
| UAL | UNITED AIRLS HLDGS INC | 0.02% | 10,401 | $828,232 | -355,974 | -97.16% | $79.63 | 13F |
| VLTO | VERALTO CORP | 0.02% | 5,475 | $552,701 | | No Change | $100.95 | 13F |
| CRH | CRH PLC | 0.02% | 8,460 | $776,628 | -5,590 | -39.79% | $91.8 | 13F |
| IONS | IONIS PHARMACEUTICALS INC | 0.01% | 10,800 | $426,708 | | No Change | $39.51 | 13F |
| PEPG | PEPGEN INC | 0.01% | 300,000 | $333,000 | -1,360,932 | -81.94% | $1.11 | 13F |
| STE | STERIS PLC | 0.01% | 1,530 | $367,537 | | No Change | $240.22 | 13F |
| SRPT | SAREPTA THERAPEUTICS INC | 0.00922% | 17,888 | $305,885 | | No Change | $17.1 | 13F |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 0.00896% | 3,260 | $297,345 | | No Change | $91.21 | 13F |
| PACS | PACS GROUP INC | 0.00779% | 20,000 | $258,400 | | No Change | $12.92 | 13F |
| BAX | BAXTER INTL INC | 0.00728% | 7,970 | $241,332 | | No Change | $30.28 | 13F |
| ALGN | ALIGN TECHNOLOGY INC | 0.00628% | 1,100 | $208,263 | 1,100 | New | $189.33 | 13F |
| AARD | AARDVARK THERAPEUTICS INC | | | | -312,500 | Exited | | 13F |
| ALNY | ALNYLAM PHARMACEUTICALS INC | | | | -9,370 | Exited | | 13F |
| ELV | ELEVANCE HEALTH INC | | | | -2,740 | Exited | | 13F |
| BIOA | BIOAGE LABS INC | | | | -1,452,336 | Exited | | 13F |
| CMG | CHIPOTLE MEXICAN GRILL INC | | | | -539,540 | Exited | | 13F |
| IRON | DISC MEDICINE INC | | | | -80,000 | Exited | | 13F |
| ITCI | INTRA-CELLULAR THERAPIES INC | | | | -700,904 | Exited | | 13F |
| ORIC | ORIC PHARMACEUTICALS INC | | | | -255,000 | Exited | | 13F |
| RBLX | ROBLOX CORP | | | | -227,710 | Exited | | 13F |
| SNY | SANOFI | | | | -83,701 | Exited | | 13F |
| SNOW | SNOWFLAKE INC | | | | -137,886 | Exited | | 13F |
| TTWO | TAKE-TWO INTERACTIVE SOFTWAR | | | | -72,400 | Exited | | 13F |
| TRVI | TREVI THERAPEUTICS INC | | | | -340,164 | Exited | | 13F |
| U | UNITY SOFTWARE INC | | | | -339,560 | Exited | | 13F |
