| SPY | SPDR S&P 500 ETF TR (Put) | 13.37% | 800,000 | $532,944,000 | 100,000 | 14.29% | $666.18 | 13F |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 4.95% | 10,478,000 | $197,510,300 | -1,057,582 | -9.17% | $18.85 | 13F |
| BNTC | Benitec Biopharma Inc. | 3.27% | 9,700,195 | $130,370,621 | -176,311 | -1.79% | | Form 4 |
| META | META PLATFORMS INC | 3.15% | 170,973 | $125,559,152 | 1,128 | 0.66% | $734.38 | 13F |
| LEGN | LEGEND BIOTECH CORP | 3.12% | 3,818,009 | $124,505,273 | 44,000 | 1.17% | $32.61 | 13F |
| ETNB | 89BIO INC | 3.05% | 8,280,000 | $121,716,000 | -5,930,000 | -41.73% | $14.7 | 13F |
| IMTX | IMMATICS N.V | 2.57% | 12,030,129 | $102,496,699 | | No Change | $8.52 | 13F |
| KO | COCA COLA CO | 2.42% | 1,455,080 | $96,500,906 | 221,850 | 17.99% | $66.32 | 13F |
| GE | GE AEROSPACE | 2.34% | 310,262 | $93,333,015 | | No Change | $300.82 | 13F |
| NVDA | NVIDIA CORPORATION | 2.26% | 483,535 | $90,217,960 | -16,027 | -3.21% | $186.58 | 13F |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 2.21% | 6,192,715 | $88,184,262 | -611,376 | -8.99% | $14.24 | 13F |
| BHVN | BIOHAVEN LTD | 2.12% | 5,620,271 | $84,360,268 | | No Change | $15.01 | 13F |
| MLYS | MINERALYS THERAPEUTICS INC | 2.03% | 2,132,133 | $80,850,483 | 387,641 | 22.22% | $37.92 | 13F |
| HD | HOME DEPOT INC | 2.01% | 197,311 | $79,948,444 | 66,590 | 50.94% | $405.19 | 13F |
| TSM | TAIWAN SEMICONDUCTOR MFG LTD | 1.94% | 277,201 | $77,419,467 | -23,200 | -7.72% | $279.29 | 13F |
| KURA | KURA ONCOLOGY INC | 1.80% | 8,116,000 | $71,826,600 | | No Change | $8.85 | 13F |
| FERG | FERGUSON ENTERPRISES INC | 1.72% | 306,260 | $68,779,871 | 116,600 | 61.48% | $224.58 | 13F |
| AVBP | ARRIVENT BIOPHARMA INC | 1.71% | 3,703,452 | $68,328,689 | 290,664 | 8.52% | $18.45 | 13F |
| APLS | APELLIS PHARMACEUTICALS INC | 1.63% | 2,878,000 | $65,129,140 | | No Change | $22.63 | 13F |
| AMD | ADVANCED MICRO DEVICES INC | 1.62% | 398,799 | $64,521,690 | | No Change | $161.79 | 13F |
| ORCL | ORACLE CORP | 1.60% | 226,318 | $63,649,674 | -4,410 | -1.91% | $281.24 | 13F |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1.52% | 2,019,000 | $60,731,520 | -259,000 | -11.37% | $30.08 | 13F |
| BAC | BANK AMERICA CORP | 1.50% | 1,160,330 | $59,861,425 | 233,140 | 25.14% | $51.59 | 13F |
| KALV | KALVISTA PHARMACEUTICALS INC | 1.46% | 4,768,712 | $58,082,912 | -186,288 | -3.76% | $12.18 | 13F |
| APO | APOLLO GLOBAL MGMT INC | 1.44% | 431,260 | $57,474,020 | 2,800 | 0.65% | $133.27 | 13F |
| MSFT | MICROSOFT CORP | 1.42% | 109,455 | $56,692,217 | 10,627 | 10.75% | $517.95 | 13F |
| PVLA | PALVELLA THERAPEUTICS INC NE | 1.29% | 822,400 | $51,556,256 | 107,937 | 15.11% | $62.69 | 13F |
| COF | CAPITAL ONE FINL CORP | 1.27% | 238,770 | $50,757,727 | 44,610 | 22.98% | $212.58 | 13F |
| DHR | DANAHER CORPORATION | 1.27% | 255,800 | $50,714,908 | 81,100 | 46.42% | $198.26 | 13F |
| RCUS | ARCUS BIOSCIENCES INC | 1.26% | 3,688,858 | $50,168,469 | | No Change | $13.6 | 13F |
| XBI | SPDR SERIES TRUST (Put) | 1.26% | 500,000 | $50,100,000 | 500,000 | New | $100.2 | 13F |
| CMPX | COMPASS THERAPEUTICS INC | 1.24% | 14,101,159 | $49,354,057 | 6,951,666 | 97.23% | $3.5 | 13F |
| FULC | FULCRUM THERAPEUTICS INC | 1.24% | 5,381,000 | $49,505,200 | 298,100 | 5.86% | $9.2 | 13F |
| AMZN | AMAZON COM INC | 1.20% | 218,547 | $47,986,365 | -39,078 | -15.17% | $219.57 | 13F |
| TSLA | TESLA INC | 1.02% | 91,252 | $40,581,589 | -1,105 | -1.2% | $444.72 | 13F |
| KDP | KEURIG DR PEPPER INC | 1.00% | 1,570,000 | $40,050,700 | 1,570,000 | New | $25.51 | 13F |
| BSX | BOSTON SCIENTIFIC CORP | 0.87% | 353,561 | $34,518,160 | | No Change | $97.63 | 13F |
| MSOS | ADVISORSHARES TR | 0.86% | 7,167,000 | $34,329,930 | 7,167,000 | New | $4.79 | 13F |
| UNH | UNITEDHEALTH GROUP INC | 0.83% | 96,220 | $33,224,766 | 28,220 | 41.5% | $345.3 | 13F |
| RNA | AVIDITY BIOSCIENCES INC | 0.82% | 750,000 | $32,677,500 | 750,000 | New | $43.57 | 13F |
| ERAS | ERASCA INC | 0.79% | 14,502,004 | $31,614,369 | | No Change | $2.18 | 13F |
| INSM | INSMED INC | 0.79% | 217,783 | $31,362,930 | -21,000 | -8.79% | $144.01 | 13F |
| PROK | PROKIDNEY CORP | 0.75% | 12,341,266 | $29,865,864 | 12,341,266 | New | $2.42 | 13F |
| CRM | SALESFORCE INC | 0.74% | 125,250 | $29,684,250 | 125,250 | New | $237 | 13F |
| DKS | DICKS SPORTING GOODS INC | 0.71% | 128,290 | $28,508,604 | -132,175 | -50.75% | $222.22 | 13F |
| AURA | AURA BIOSCIENCES INC | 0.68% | 4,372,884 | $27,024,423 | | No Change | $6.18 | 13F |
| KDP | KEURIG DR PEPPER INC (Call) | 0.64% | 1,000,000 | $25,510,000 | 1,000,000 | New | $25.51 | 13F |
| JNJ | JOHNSON & JOHNSON | 0.62% | 132,786 | $24,621,180 | | No Change | $185.42 | 13F |
| GLUE | MONTE ROSA THERAPEUTICS INC | 0.62% | 3,360,000 | $24,897,600 | | No Change | $7.41 | 13F |
| BIIB | BIOGEN INC | 0.59% | 168,190 | $23,560,055 | 16,300 | 10.73% | $140.08 | 13F |
| ZURA | ZURA BIO LTD | 0.59% | 5,472,891 | $23,697,618 | 611,952 | 12.59% | $4.33 | 13F |
| MRVL | MARVELL TECHNOLOGY INC | 0.57% | 272,300 | $22,892,261 | 272,300 | New | $84.07 | 13F |
| CTNM | CONTINEUM THERAPEUTICS INC | 0.51% | 1,720,000 | $20,210,000 | | No Change | $11.75 | 13F |
| NOW | SERVICENOW INC | 0.51% | 22,000 | $20,246,160 | 22,000 | New | $920.28 | 13F |
| SNOW | SNOWFLAKE INC | 0.50% | 89,200 | $20,119,060 | 89,200 | New | $225.55 | 13F |
| GS | GOLDMAN SACHS GROUP INC | 0.48% | 24,108 | $19,198,406 | | No Change | $796.35 | 13F |
| MRK | MERCK & CO INC | 0.46% | 219,178 | $18,395,610 | | No Change | $83.93 | 13F |
| PINS | PINTEREST INC | 0.40% | 497,185 | $15,994,441 | 67,160 | 15.62% | $32.17 | 13F |
| ABEO | ABEONA THERAPEUTICS INC | 0.35% | 2,676,000 | $14,129,280 | | No Change | $5.28 | 13F |
| RCKT | ROCKET PHARMACEUTICALS INC | 0.31% | 3,843,333 | $12,529,266 | -300,000 | -7.24% | $3.26 | 13F |
| REGN | REGENERON PHARMACEUTICALS | 0.25% | 17,730 | $9,969,047 | 9,100 | 105.45% | $562.27 | 13F |
| IFRX | INFLARX NV | 0.22% | 6,483,910 | $8,688,439 | | No Change | $1.34 | 13F |
| MOLN | MOLECULAR PARTNERS AG | 0.21% | 2,221,494 | $8,241,743 | | No Change | $3.71 | 13F |
| WHWK | WHITEHAWK THERAPEUTICS INC | 0.18% | 3,700,000 | $7,030,000 | | No Change | $1.9 | 13F |
| ABT | ABBOTT LABS | 0.17% | 51,020 | $6,833,619 | 10,500 | 25.91% | $133.94 | 13F |
| TMO | THERMO FISHER SCIENTIFIC INC | 0.16% | 13,400 | $6,499,268 | 5,500 | 69.62% | $485.02 | 13F |
| STRO | SUTRO BIOPHARMA INC | 0.14% | 6,488,324 | $5,634,461 | | No Change | $0.87 | 13F |
| ELAN | ELANCO ANIMAL HEALTH INC | 0.13% | 253,600 | $5,107,504 | | No Change | $20.14 | 13F |
| EXAS | EXACT SCIENCES CORP | 0.13% | 94,100 | $5,148,211 | | No Change | $54.71 | 13F |
| COR | CENCORA INC | 0.10% | 12,488 | $3,902,875 | | No Change | $312.53 | 13F |
| UTHR | UNITED THERAPEUTICS CORP DEL | 0.08% | 7,500 | $3,144,075 | 7,500 | New | $419.21 | 13F |
| KZR | KEZAR LIFE SCIENCES INC | 0.07% | 716,759 | $2,795,360 | | No Change | $3.9 | 13F |
| MTD | METTLER TOLEDO INTERNATIONAL | 0.06% | 1,964 | $2,411,026 | | No Change | $1227.61 | 13F |
| ISRG | INTUITIVE SURGICAL INC | 0.06% | 5,200 | $2,325,596 | | No Change | $447.23 | 13F |
| MDT | MEDTRONIC PLC | 0.06% | 25,060 | $2,386,714 | | No Change | $95.24 | 13F |
| DXCM | DEXCOM INC | 0.05% | 31,680 | $2,131,747 | | No Change | $67.29 | 13F |
| SYK | STRYKER CORPORATION | 0.05% | 5,860 | $2,166,266 | | No Change | $369.67 | 13F |
| MCK | MCKESSON CORP | 0.04% | 1,830 | $1,413,748 | | No Change | $772.54 | 13F |
| NTRA | NATERA INC | 0.04% | 10,100 | $1,625,797 | | No Change | $160.97 | 13F |
| GLPG | GALAPAGOS NV | 0.03% | 37,111 | $1,285,525 | | No Change | $34.64 | 13F |
| HCA | HCA HEALTHCARE INC | 0.03% | 3,190 | $1,359,578 | | No Change | $426.2 | 13F |
| IQV | IQVIA HLDGS INC | 0.03% | 7,175 | $1,362,820 | | No Change | $189.94 | 13F |
| A | AGILENT TECHNOLOGIES INC | 0.02% | 4,990 | $640,467 | | No Change | $128.35 | 13F |
| AVTR | AVANTOR INC | 0.02% | 71,850 | $896,688 | | No Change | $12.48 | 13F |
| IONS | IONIS PHARMACEUTICALS INC | 0.02% | 10,800 | $706,536 | | No Change | $65.42 | 13F |
| RMD | RESMED INC | 0.02% | 2,390 | $654,215 | | No Change | $273.73 | 13F |
| WAT | WATERS CORP | 0.02% | 3,150 | $944,402 | | No Change | $299.81 | 13F |
| EW | EDWARDS LIFESCIENCES CORP | 0.02% | 11,100 | $863,247 | | No Change | $77.77 | 13F |
| VLTO | VERALTO CORP | 0.01% | 5,475 | $583,690 | | No Change | $106.61 | 13F |
| STE | STERIS PLC | 0.00949% | 1,530 | $378,583 | | No Change | $247.44 | 13F |
| SRPT | SAREPTA THERAPEUTICS INC | 0.00865% | 17,888 | $344,702 | | No Change | $19.27 | 13F |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 0.00805% | 3,260 | $321,110 | | No Change | $98.5 | 13F |
| PACS | PACS GROUP INC | 0.00689% | 20,000 | $274,600 | | No Change | $13.73 | 13F |
| ALGN | ALIGN TECHNOLOGY INC | | | | -1,100 | Exited | | 13F |
| BAX | BAXTER INTL INC | | | | -7,970 | Exited | | 13F |
| CZR | CAESARS ENTERTAINMENT INC NE | | | | -18,875 | Exited | | 13F |
| DDOG | DATADOG INC | | | | -178,832 | Exited | | 13F |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | | | | -532,280 | Exited | | 13F |
| IWM | ISHARES TR (Put) | | | | -702,500 | Exited | | 13F |
| KYMR | KYMERA THERAPEUTICS INC | | | | -275,000 | Exited | | 13F |
| MRNA | MODERNA INC | | | | -517,163 | Exited | | 13F |
| NVDA | NVIDIA CORPORATION (Call) | | | | -500,000 | Exited | | 13F |
| OS | ONESTREAM INC | | | | -33,080 | Exited | | 13F |
| PEPG | PEPGEN INC | | | | -300,000 | Exited | | 13F |
| TSHA | TAYSHA GENE THERAPIES INC | | | | -3,217,449 | Exited | | 13F |
| UAL | UNITED AIRLS HLDGS INC | | | | -10,401 | Exited | | 13F |
| WING | WINGSTOP INC | | | | -3,961 | Exited | | 13F |
| CRH | CRH PLC | | | | -8,460 | Exited | | 13F |
| PROK | PROKIDNEY CORP | | | | -12,341,266 | Exited | | 13F |
