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| Stock | Company | % Portfolio | Shares Held | Market Value | Change in Shares | % Change | Quarter End Price | Source |
|---|---|---|---|---|---|---|---|---|
| SPY | SPDR S&P 500 ETF TR (Put) | 8.57% | 450,000 | $235,381,500 | 450,000 | New | $523.07 | 13F |
| BHVN | BIOHAVEN LTD | 7.97% | 4,003,046 | $218,926,586 | -569,790 | -12.46% | $54.69 | 13F |
| KURA | KURA ONCOLOGY INC | 5.49% | 7,069,627 | $150,795,144 | 123,397 | 1.78% | $21.33 | 13F |
| ACLX | ARCELLX INC | 3.96% | 1,562,354 | $108,661,721 | -873,620 | -35.86% | $69.55 | 13F |
| QQQ | INVESCO QQQ TR (Put) | 3.15% | 195,000 | $86,581,950 | 195,000 | New | $444.01 | 13F |
| META | META PLATFORMS INC | 3.07% | 173,605 | $84,299,116 | -46,578 | -21.15% | $485.58 | 13F |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 2.85% | 1,676,811 | $78,290,306 | -449,495 | -21.14% | $46.69 | 13F |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 2.84% | 7,877,297 | $78,064,013 | -595,804 | -7.03% | $9.91 | 13F |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 2.83% | 3,763,888 | $77,799,565 | -292,959 | -7.22% | $20.67 | 13F |
| ETNB | 89BIO INC | 2.67% | 6,298,004 | $73,308,767 | 1,409,570 | 28.83% | $11.64 | 13F |
| RPRX | ROYALTY PHARMA PLC | 2.49% | 2,250,361 | $68,343,464 | -1,637,341 | -42.12% | $30.37 | 13F |
| ITCI | INTRA-CELLULAR THERAPIES INC | 2.42% | 959,198 | $66,376,502 | -206,750 | -17.73% | $69.2 | 13F |
| AMZN | AMAZON COM INC | 2.34% | 356,962 | $64,388,806 | -11,127 | -3.02% | $180.38 | 13F |
| AMD | ADVANCED MICRO DEVICES INC | 2.25% | 341,699 | $61,673,253 | 8,231 | 2.47% | $180.49 | 13F |
| INSM | INSMED INC | 2.00% | 2,023,000 | $54,883,990 | -661,487 | -24.64% | $27.13 | 13F |
| CI | THE CIGNA GROUP | 1.81% | 137,139 | $49,807,513 | 40,839 | 42.41% | $363.19 | 13F |
| KALV | KALVISTA PHARMACEUTICALS INC | 1.81% | 4,192,005 | $49,717,179 | 1,508,000 | 56.18% | $11.86 | 13F |
| VZ | VERIZON COMMUNICATIONS INC | 1.80% | 1,179,452 | $49,489,806 | 462,602 | 64.53% | $41.96 | 13F |
| ARGX | ARGENX SE | 1.75% | 121,900 | $47,994,468 | 68,200 | 127% | $393.72 | 13F |
| MRNS | MARINUS PHARMACEUTICALS INC | 1.68% | 5,108,520 | $46,181,021 | -237,599 | -4.44% | $9.04 | 13F |
| GS | GOLDMAN SACHS GROUP INC | 1.67% | 109,890 | $45,899,954 | -420 | -0.38% | $417.69 | 13F |
| TSM | TAIWAN SEMICONDUCTOR MFG LTD | 1.63% | 329,352 | $44,808,340 | -58,880 | -15.17% | $136.05 | 13F |
| T | AT&T INC | 1.54% | 2,398,619 | $42,215,694 | 1,178,539 | 96.6% | $17.6 | 13F |
| APO | APOLLO GLOBAL MGMT INC | 1.52% | 370,636 | $41,678,018 | -170,184 | -31.47% | $112.45 | 13F |
| FERG | FERGUSON PLC NEW | 1.35% | 169,280 | $36,975,830 | -6,810 | -3.87% | $218.43 | 13F |
| GE | GENERAL ELECTRIC CO | 1.33% | 207,447 | $36,413,172 | -148,733 | -41.76% | $175.53 | 13F |
| KO | COCA COLA CO | 1.22% | 546,500 | $33,434,870 | 546,500 | New | $61.18 | 13F |
| MSFT | MICROSOFT CORP | 1.22% | 79,317 | $33,370,248 | -82,607 | -51.02% | $420.72 | 13F |
| STRO | SUTRO BIOPHARMA INC | 1.19% | 5,778,188 | $32,646,762 | No Change | $5.65 | 13F | |
| MCK | MCKESSON CORP | 1.11% | 56,639 | $30,406,647 | -6,821 | -10.75% | $536.85 | 13F |
| AAPL | APPLE INC | 1.10% | 176,680 | $30,297,086 | 176,680 | New | $171.48 | 13F |
| CRH | CRH PLC | 1.05% | 335,580 | $28,947,131 | 335,580 | New | $86.26 | 13F |
| AVBP | ARRIVENT BIOPHARMA INC | 1.02% | 1,563,709 | $27,927,843 | 1,563,709 | New | $17.86 | 13F |
| FULC | FULCRUM THERAPEUTICS INC | 0.98% | 2,848,486 | $26,889,708 | -2,670,395 | -48.39% | $9.44 | 13F |
| ELV | ELEVANCE HEALTH INC | 0.96% | 50,925 | $26,406,650 | -2,810 | -5.23% | $518.54 | 13F |
| CTNM | Contineum Therapeutics, Inc. | 0.96% | 1,720,000 | $26,488,000 | 1,720,000 | New | 13G | |
| ORCL | ORACLE CORP | 0.90% | 196,674 | $24,704,221 | -125,376 | -38.93% | $125.61 | 13F |
| CMG | CHIPOTLE MEXICAN GRILL INC | 0.84% | 7,970 | $23,166,957 | -740 | -8.5% | $2906.77 | 13F |
| BCYC | BICYCLE THERAPEUTICS PLC | 0.83% | 914,476 | $22,770,452 | No Change | $24.9 | 13F | |
| PEPG | PEPGEN INC | 0.81% | 1,520,932 | $22,357,700 | 1,034,321 | 212.56% | $14.7 | 13F |
| BSX | BOSTON SCIENTIFIC CORP | 0.76% | 303,035 | $20,754,867 | -391,066 | -56.34% | $68.49 | 13F |
| FATE | FATE THERAPEUTICS INC | 0.68% | 2,562,852 | $18,811,334 | 2,562,852 | New | $7.34 | 13F |
| RCUS | ARCUS BIOSCIENCES INC | 0.66% | 957,304 | $18,073,900 | No Change | $18.88 | 13F | |
| ABEO | ABEONA THERAPEUTICS INC. | 0.63% | 3,685,503 | $16,953,314 | 3,685,503 | New | 13G | |
| HLT | HILTON WORLDWIDE HLDGS INC | 0.61% | 78,502 | $16,745,262 | -30,760 | -28.15% | $213.31 | 13F |
| CRM | SALESFORCE INC | 0.60% | 55,050 | $16,579,959 | 55,050 | New | $301.18 | 13F |
| SBUX | STARBUCKS CORP | 0.58% | 172,951 | $15,805,992 | 172,951 | New | $91.39 | 13F |
| GPN | GLOBAL PMTS INC | 0.52% | 106,094 | $14,180,524 | -6,286 | -5.59% | $133.66 | 13F |
| JNJ | JOHNSON & JOHNSON | 0.52% | 90,097 | $14,252,444 | No Change | $158.19 | 13F | |
| PINS | PINTEREST INC | 0.50% | 395,851 | $13,724,154 | 395,851 | New | $34.67 | 13F |
| MREO | MEREO BIOPHARMA GROUP PLC | 0.44% | 3,653,494 | $12,056,530 | -3,717,344 | -50.43% | $3.3 | 13F |
| BNTC | Benitec Biopharma Inc. | 0.42% | 1,700,850 | $11,429,712 | 1,496,630 | 732.85% | 13D | |
| SNY | SANOFI | 0.37% | 210,701 | $10,240,069 | 39,700 | 23.22% | $48.6 | 13F |
| IMTX | IMMATICS N.V | 0.36% | 946,563 | $9,948,377 | 946,563 | New | $10.51 | 13F |
| TERN | TERNS PHARMACEUTICALS INC | 0.33% | 1,363,675 | $8,945,708 | -4,473,451 | -76.64% | $6.56 | 13F |
| IFRX | INFLARX NV | 0.32% | 5,733,910 | $8,830,221 | No Change | $1.54 | 13F | |
| ELAN | ELANCO ANIMAL HEALTH INC | 0.30% | 507,200 | $8,257,216 | -107,100 | -17.43% | $16.28 | 13F |
| RVNC | REVANCE THERAPEUTICS INC | 0.29% | 1,600,000 | $7,872,000 | 1,600,000 | New | $4.92 | 13F |
| UNH | UNITEDHEALTH GROUP INC | 0.27% | 15,123 | $7,481,348 | 2,300 | 17.94% | $494.7 | 13F |
| ZURA | ZURA BIO LTD | 0.27% | 2,850,000 | $7,324,500 | No Change | $2.57 | 13F | |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 0.25% | 75,000 | $6,818,250 | 75,000 | New | $90.91 | 13F |
| KZR | KEZAR LIFE SCIENCES INC | 0.24% | 7,167,591 | $6,462,300 | No Change | $0.9 | 13F | |
| KRRO | KORRO BIO INC | 0.24% | 73,821 | $6,643,890 | No Change | $90 | 13F | |
| PROK | PROKIDNEY CORP | 0.23% | 3,867,847 | $6,343,269 | No Change | $1.64 | 13F | |
| SYRE | SPYRE THERAPEUTICS INC | 0.22% | 162,395 | $6,159,642 | No Change | $37.93 | 13F | |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 0.18% | 32,660 | $4,881,037 | 22,800 | 231.24% | $149.45 | 13F |
| DHR | DANAHER CORPORATION | 0.15% | 16,427 | $4,102,150 | No Change | $249.72 | 13F | |
| TMO | THERMO FISHER SCIENTIFIC INC | 0.15% | 7,260 | $4,219,585 | No Change | $581.21 | 13F | |
| ABT | ABBOTT LABS | 0.14% | 33,520 | $3,809,883 | No Change | $113.66 | 13F | |
| GILD | GILEAD SCIENCES INC | 0.14% | 50,700 | $3,713,775 | 28,000 | 123.35% | $73.25 | 13F |
| TEVA | TEVA PHARMACEUTICAL INDS LTD | 0.14% | 268,100 | $3,782,891 | -229,300 | -46.1% | $14.11 | 13F |
| KVUE | KENVUE INC | 0.13% | 171,596 | $3,682,450 | No Change | $21.46 | 13F | |
| COR | CENCORA INC | 0.11% | 12,488 | $3,034,459 | No Change | $242.99 | 13F | |
| MTD | METTLER TOLEDO INTERNATIONAL | 0.10% | 1,964 | $2,614,654 | 1,964 | New | $1331.29 | 13F |
| TRML | TOURMALINE BIO INC | 0.10% | 125,000 | $2,862,500 | 125,000 | New | $22.9 | 13F |
| COGT | COGENT BIOSCIENCES INC | 0.08% | 316,000 | $2,123,520 | -3,394,539 | -91.48% | $6.72 | 13F |
| NTRA | NATERA INC | 0.08% | 24,600 | $2,249,916 | No Change | $91.46 | 13F | |
| ISRG | INTUITIVE SURGICAL INC | 0.08% | 5,200 | $2,075,268 | 2,130 | 69.38% | $399.09 | 13F |
| AVTR | AVANTOR INC | 0.07% | 71,850 | $1,837,205 | 33,600 | 87.84% | $25.57 | 13F |
| IQV | IQVIA HLDGS INC | 0.07% | 7,175 | $1,814,486 | No Change | $252.89 | 13F | |
| GLPG | GALAPAGOS NV | 0.06% | 47,200 | $1,519,840 | No Change | $32.2 | 13F | |
| MOLN | MOLECULAR PARTNERS AG | 0.06% | 400,000 | $1,680,000 | No Change | $4.2 | 13F | |
| SYK | STRYKER CORPORATION | 0.06% | 4,360 | $1,560,313 | No Change | $357.87 | 13F | |
| MDT | MEDTRONIC PLC | 0.06% | 17,460 | $1,521,639 | No Change | $87.15 | 13F | |
| CVS | CVS HEALTH CORP | 0.05% | 17,170 | $1,369,479 | No Change | $79.76 | 13F | |
| AKLI | AKILI INC | 0.04% | 3,841,718 | $1,112,562 | No Change | $0.29 | 13F | |
| HCA | HCA HEALTHCARE INC | 0.04% | 3,190 | $1,063,961 | 3,190 | New | $333.53 | 13F |
| ILMN | ILLUMINA INC | 0.04% | 8,730 | $1,198,804 | No Change | $137.32 | 13F | |
| WAT | WATERS CORP | 0.04% | 3,150 | $1,084,325 | No Change | $344.23 | 13F | |
| EW | EDWARDS LIFESCIENCES CORP | 0.04% | 11,100 | $1,060,716 | 11,100 | New | $95.56 | 13F |
| A | AGILENT TECHNOLOGIES INC | 0.03% | 4,990 | $726,095 | No Change | $145.51 | 13F | |
| DXCM | DEXCOM INC | 0.03% | 5,880 | $815,556 | No Change | $138.7 | 13F | |
| MS | MORGAN STANLEY | 0.03% | 7,641 | $719,477 | 2,841 | 59.19% | $94.16 | 13F |
| PTGX | PROTAGONIST THERAPEUTICS INC | 0.03% | 30,500 | $882,365 | 30,500 | New | $28.93 | 13F |
| HUM | HUMANA INC | 0.02% | 1,950 | $676,104 | 1,950 | New | $346.72 | 13F |
| IONS | IONIS PHARMACEUTICALS INC | 0.02% | 10,800 | $468,180 | 10,800 | New | $43.35 | 13F |
| RMD | RESMED INC | 0.02% | 2,390 | $473,292 | 2,390 | New | $198.03 | 13F |
| VLTO | VERALTO CORP | 0.02% | 5,475 | $485,414 | No Change | $88.66 | 13F | |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 0.02% | 3,260 | $430,255 | 3,260 | New | $131.98 | 13F |
| ALGN | ALIGN TECHNOLOGY INC | 0.01% | 1,100 | $360,712 | 1,100 | New | $327.92 | 13F |
| BAX | BAXTER INTL INC | 0.01% | 7,970 | $340,638 | 7,970 | New | $42.74 | 13F |
| STE | STERIS PLC | 0.01% | 1,530 | $343,975 | 1,530 | New | $224.82 | 13F |
| CRL | CHARLES RIV LABS INTL INC | 0.00996% | 1,010 | $273,660 | No Change | $270.95 | 13F | |
| AGIO | AGIOS PHARMACEUTICALS INC | -399,451 | Exited | 13F | ||||
| ANAB | ANAPTYSBIO INC | -354,872 | Exited | 13F | ||||
| AZN | ASTRAZENECA PLC | -70,490 | Exited | 13F | ||||
| TECH | BIO-TECHNE CORP | -2,600 | Exited | 13F | ||||
| IDXX | IDEXX LABS INC | -920 | Exited | 13F | ||||
| INCY | INCYTE CORP | -37,600 | Exited | 13F | ||||
| KWEB | KRANESHARES TR (Call) | -900,000 | Exited | 13F | ||||
| LVS | LAS VEGAS SANDS CORP | -738,163 | Exited | 13F | ||||
| MRK | MERCK & CO INC | -15,500 | Exited | 13F | ||||
| PFE | PFIZER INC | -50,300 | Exited | 13F | ||||
| SANA | SANA BIOTECHNOLOGY INC | -1,606,056 | Exited | 13F | ||||
| UTHR | UNITED THERAPEUTICS CORP DEL | -1,360 | Exited | 13F |