| HYG | ISHARES TR (Put) | 12.96% | 39,000,000 | $3,166,410,000 | 21,000,000 | 116.67% | $81.19 | 13F |
| SPY | SPDR S&P 500 ETF TR (Put) | 9.27% | 3,400,000 | $2,265,012,000 | 3,400,000 | New | $666.18 | 13F |
| MSFT | MICROSOFT CORP | 4.06% | 1,913,135 | $990,908,273 | 165,300 | 9.46% | $517.95 | 13F |
| RSP | INVESCO EXCHANGE TRADED FD T (Put) | 3.96% | 5,100,000 | $967,470,000 | 2,800,000 | 121.74% | $189.7 | 13F |
| AON | AON PLC | 3.33% | 2,278,017 | $812,295,302 | 291,600 | 14.68% | $356.58 | 13F |
| EXEL | EXELIXIS INC | 3.3% | 19,501,500 | $805,411,950 | 3,466,000 | 21.61% | $41.3 | 13F |
| AMZN | AMAZON COM INC | 3.15% | 3,505,700 | $769,746,549 | 471,100 | 15.52% | $219.57 | 13F |
| NTRA | NATERA INC | 2.8% | 4,253,452 | $684,678,168 | -568,357 | -11.79% | $160.97 | 13F |
| RVMD | REVOLUTION MEDICINES INC | 2.8% | 14,625,692 | $683,019,816 | 300,000 | 2.09% | $46.7 | 13F |
| UNH | UNITEDHEALTH GROUP INC | 2.67% | 1,886,500 | $651,408,450 | 269,200 | 16.65% | $345.3 | 13F |
| HIMS | HIMS & HERS HEALTH INC | 2.5% | 10,746,852 | $609,561,445 | 2,533,271 | 30.84% | $56.72 | 13F |
| TMO | THERMO FISHER SCIENTIFIC INC | 2.5% | 1,258,241 | $610,272,050 | -125,000 | -9.04% | $485.02 | 13F |
| DIS | DISNEY WALT CO | 2.44% | 5,198,968 | $595,281,836 | 324,700 | 6.66% | $114.5 | 13F |
| CRM | SALESFORCE INC | 2.39% | 2,462,310 | $583,567,470 | 353,200 | 16.75% | $237 | 13F |
| ADSK | AUTODESK INC | 2.16% | 1,662,852 | $528,238,195 | -81,800 | -4.69% | $317.67 | 13F |
| BSX | BOSTON SCIENTIFIC CORP | 1.9% | 4,746,557 | $463,406,360 | 765,500 | 19.23% | $97.63 | 13F |
| IBIT | ISHARES BITCOIN TRUST ETF | 1.86% | 6,992,700 | $454,525,500 | -27,350 | -0.39% | $65 | 13F |
| WAB | WABTEC | 1.81% | 2,205,098 | $442,055,996 | 896,900 | 68.56% | $200.47 | 13F |
| BBIO | BRIDGEBIO PHARMA INC | 1.74% | 8,192,000 | $425,492,480 | 292,000 | 3.7% | $51.94 | 13F |
| PTGX | PROTAGONIST THERAPEUTICS INC | 1.68% | 6,196,006 | $411,600,679 | 24,000 | 0.39% | $66.43 | 13F |
| TRU | TRANSUNION | 1.62% | 4,732,075 | $396,453,244 | -672,500 | -12.44% | $83.78 | 13F |
| ARMK | ARAMARK | 1.41% | 8,996,202 | $345,454,157 | -3,903,499 | -30.26% | $38.4 | 13F |
| INTU | INTUIT | 1.36% | 488,088 | $333,320,176 | -48,570 | -9.05% | $682.91 | 13F |
| K | KELLANOVA | 1.32% | 3,943,853 | $323,474,823 | 3,943,853 | New | $82.02 | 13F |
| ADI | ANALOG DEVICES INC | 1.31% | 1,299,500 | $319,287,150 | 27,300 | 2.15% | $245.7 | 13F |
| NDAQ | NASDAQ INC | 1.31% | 3,623,043 | $320,458,153 | -460,700 | -11.28% | $88.45 | 13F |
| SCHW | SCHWAB CHARLES CORP | 1.27% | 3,251,657 | $310,435,694 | -707,400 | -17.87% | $95.47 | 13F |
| LLY | ELI LILLY & CO (Put) | 1.17% | 375,000 | $286,125,000 | 375,000 | New | $763 | 13F |
| NYT | NEW YORK TIMES CO | 1.17% | 4,985,745 | $286,181,763 | -623,801 | -11.12% | $57.4 | 13F |
| GOOG | ALPHABET INC | 1.12% | 1,120,940 | $273,004,937 | -640,900 | -36.38% | $243.55 | 13F |
| CBRE | CBRE GROUP INC | 1.04% | 1,616,038 | $254,622,947 | -497,100 | -23.52% | $157.56 | 13F |
| MCK | MCKESSON CORP | 1.03% | 327,100 | $252,697,834 | 12,500 | 3.97% | $772.54 | 13F |
| BEAM | BEAM THERAPEUTICS INC | 1% | 10,063,111 | $244,231,704 | 50,000 | 0.5% | $24.27 | 13F |
| CRNX | CRINETICS PHARMACEUTICALS IN | 0.98% | 5,770,098 | $240,324,582 | 1,124,000 | 24.19% | $41.65 | 13F |
| ETHA | ISHARES ETHEREUM TR | 0.96% | 7,450,730 | $234,772,502 | 7,450,730 | New | $31.51 | 13F |
| AGIO | AGIOS PHARMACEUTICALS INC | 0.95% | 5,781,066 | $232,051,989 | 13,600 | 0.24% | $40.14 | 13F |
| V | VISA INC | 0.84% | 599,810 | $204,763,138 | 291,000 | 94.23% | $341.38 | 13F |
| LQDA | LIQUIDIA CORPORATION | 0.8% | 8,565,638 | $194,782,608 | 4,326,876 | 102.08% | $22.74 | 13F |
| NSC | NORFOLK SOUTHN CORP | 0.76% | 615,000 | $184,752,150 | 615,000 | New | $300.41 | 13F |
| IQV | IQVIA HLDGS INC | 0.73% | 938,551 | $178,268,377 | -2,912,800 | -75.63% | $189.94 | 13F |
| LNTH | LANTHEUS HLDGS INC | 0.73% | 3,477,227 | $178,346,973 | -3,245,000 | -48.27% | $51.29 | 13F |
| WWD | WOODWARD INC | 0.64% | 621,973 | $157,178,797 | -292,700 | -32% | $252.71 | 13F |
| MA | MASTERCARD INCORPORATED | 0.5% | 213,771 | $121,595,083 | 61,700 | 40.57% | $568.81 | 13F |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 0.43% | 4,331,318 | $105,034,462 | -198,000 | -4.37% | $24.25 | 13F |
| TEVA | TEVA PHARMACEUTICAL INDS LTD | 0.41% | 4,997,000 | $100,939,400 | 4,997,000 | New | $20.2 | 13F |
| TNGX | TANGO THERAPEUTICS INC | 0.37% | 10,757,000 | $90,358,800 | 1,600,000 | 17.47% | $8.4 | 13F |
| BBNX | BETA BIONICS INC | 0.35% | 4,313,920 | $85,717,590 | 110,000 | 2.62% | $19.87 | 13F |
| THC | TENET HEALTHCARE CORP | 0.34% | 414,000 | $84,058,560 | -115,000 | -21.74% | $203.04 | 13F |
| GRAL | GRAIL INC | 0.33% | 1,349,000 | $79,766,370 | 847,000 | 168.73% | $59.13 | 13F |
| EHC | ENCOMPASS HEALTH CORP | 0.3% | 571,000 | $72,528,420 | -137,000 | -19.35% | $127.02 | 13F |
| ABVX | ABIVAX SA | 0.28% | 805,000 | $68,344,500 | 805,000 | New | $84.9 | 13F |
| OSCR | OSCAR HEALTH INC | 0.28% | 3,639,000 | $68,886,270 | 2,163,000 | 146.54% | $18.93 | 13F |
| MARA | MARA HOLDINGS INC | 0.27% | 3,660,000 | $66,831,600 | 2,825,000 | 338.32% | $18.26 | 13F |
| MLYS | MINERALYS THERAPEUTICS INC | 0.26% | 1,673,053 | $63,442,170 | 1,673,053 | New | $37.92 | 13F |
| VNET | VNET GROUP INC | 0.23% | 5,489,120 | $56,702,610 | 2,495,000 | 83.33% | $10.33 | 13F |
| CDTX | CIDARA THERAPEUTICS INC | 0.2% | 508,000 | $48,646,080 | 308,000 | 154% | $95.76 | 13F |
| ALNY | ALNYLAM PHARMACEUTICALS INC (Put) | 0.19% | 100,000 | $45,600,000 | 100,000 | New | $456 | 13F |
| COOP | MR COOPER GROUP INC | 0.19% | 222,000 | $46,795,380 | 99,500 | 81.22% | $210.79 | 13F |
| GDLC | GRAYSCALE COINDESK CRYPTO | 0.19% | 851,193 | $47,581,689 | 851,193 | New | $55.9 | 13F |
| NKTR | NEKTAR THERAPEUTICS | 0.18% | 791,000 | $45,007,900 | 791,000 | New | $56.9 | 13F |
| CAH | CARDINAL HEALTH INC | 0.16% | 253,000 | $39,710,880 | -201,000 | -44.27% | $156.96 | 13F |
| JOYY | JOYY INC | 0.15% | 625,000 | $36,631,250 | -162,906 | -20.68% | $58.61 | 13F |
| FLUT | FLUTTER ENTMT PLC | 0.14% | 137,369 | $34,891,726 | -43,860 | -24.2% | $254 | 13F |
| QURE | UNIQURE NV | 0.14% | 565,000 | $32,979,050 | 551,000 | 3935.71% | $58.37 | 13F |
| ASMB | ASSEMBLY BIOSCIENCES INC | 0.13% | 1,227,590 | $31,426,304 | 1,227,590 | New | $25.6 | 13F |
| EDU | NEW ORIENTAL ED & TECHNOLOGY | 0.12% | 565,150 | $29,992,511 | -590,000 | -51.08% | $53.07 | 13F |
| WAY | WAYSTAR HLDG CORP | 0.12% | 750,000 | $28,440,000 | 137,000 | 22.35% | $37.92 | 13F |
| BIDU | BAIDU INC | 0.11% | 207,996 | $27,407,633 | 207,996 | New | $131.77 | 13F |
| DOCS | DOXIMITY INC | 0.11% | 374,000 | $27,358,100 | 374,000 | New | $73.15 | 13F |
| PRME | PRIME MEDICINE INC | 0.11% | 4,750,000 | $26,315,000 | 4,000,000 | 533.33% | $5.54 | 13F |
| ENTA | ENANTA PHARMACEUTICALS INC | 0.1% | 2,122,262 | $25,403,476 | | No Change | $11.97 | 13F |
| SGRY | SURGERY PARTNERS INC | 0.08% | 871,830 | $18,866,401 | -1,054,170 | -54.73% | $21.64 | 13F |
| TYRA | TYRA BIOSCIENCES INC | 0.07% | 1,143,818 | $16,002,014 | | No Change | $13.99 | 13F |
| NTLA | INTELLIA THERAPEUTICS INC | 0.04% | 607,200 | $10,486,344 | 607,200 | New | $17.27 | 13F |
| SVRA | SAVARA INC | 0.04% | 2,500,000 | $8,925,000 | -4,335,000 | -63.42% | $3.57 | 13F |
| SLNO | SOLENO THERAPEUTICS INC | 0.04% | 153,000 | $10,342,800 | 148,000 | 2960% | $67.6 | 13F |
| TECX | TECTONIC THERAPEUTIC INC | 0.04% | 640,000 | $10,041,600 | -213,050 | -24.98% | $15.69 | 13F |
| NVAX | NOVAVAX INC | 0.03% | 780,000 | $6,762,600 | 764,000 | 4775% | $8.67 | 13F |
| ALE | ALLETE INC | 0.02% | 75,000 | $4,980,000 | 75,000 | New | $66.4 | 13F |
| SOXX | ISHARES TR | 0.02% | 18,907 | $5,126,066 | 18,907 | New | $271.12 | 13F |
| SDGR | SCHRODINGER INC | 0.02% | 284,000 | $5,697,040 | -822,000 | -74.32% | $20.06 | 13F |
| TVRD | TVARDI THERAPEUTICS INC | 0.0069% | 43,225 | $1,684,478 | | No Change | $38.97 | 13F |
| ALVO | ALVOTECH | 0.00669% | 199,675 | $1,635,338 | | No Change | $8.19 | 13F |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 0.00623% | 3,319 | $1,522,293 | | No Change | $458.66 | 13F |
| SMC | SUMMIT MIDSTREAM CORPORATION | 0.00489% | 58,214 | $1,195,716 | | No Change | $20.54 | 13F |
| BTSG | BRIGHTSPRING HEALTH SVCS INC | 0.00266% | 22,000 | $650,320 | | No Change | $29.56 | 13F |
| ALKS | ALKERMES PLC | 0.00255% | 20,800 | $624,000 | -670,863 | -96.99% | $30 | 13F |
| ROIV | ROIVANT SCIENCES LTD | 0.00229% | 37,000 | $559,810 | | No Change | $15.13 | 13F |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 0.00223% | 15,800 | $544,942 | | No Change | $34.49 | 13F |
| WGS | GENEDX HOLDINGS CORP | 0.00221% | 5,000 | $538,700 | -321,677 | -98.47% | $107.74 | 13F |
| GH | GUARDANT HEALTH INC | 0.00205% | 8,000 | $499,840 | | No Change | $62.48 | 13F |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 0.00201% | 26,000 | $490,100 | | No Change | $18.85 | 13F |
| AXSM | AXSOME THERAPEUTICS INC | 0.00199% | 4,000 | $485,800 | | No Change | $121.45 | 13F |
| HQY | HEALTHEQUITY INC | 0.00194% | 5,000 | $473,850 | -314,800 | -98.44% | $94.77 | 13F |
| INSM | INSMED INC | 0.00177% | 3,000 | $432,030 | | No Change | $144.01 | 13F |
| PGNY | PROGYNY INC | 0.00159% | 18,000 | $387,360 | | No Change | $21.52 | 13F |
| ONC | BEONE MEDICINES LTD | 0.00153% | 1,100 | $374,770 | | No Change | $340.7 | 13F |
| KRYS | KRYSTAL BIOTECH INC | 0.00145% | 2,000 | $353,060 | | No Change | $176.53 | 13F |
| ACLX | ARCELLX INC | 0.00134% | 4,000 | $328,400 | | No Change | $82.1 | 13F |
| CGON | CG ONCOLOGY INC | 0.00132% | 8,000 | $322,240 | | No Change | $40.28 | 13F |
| IONS | IONIS PHARMACEUTICALS INC | 0.00129% | 4,800 | $314,016 | 4,800 | New | $65.42 | 13F |
| LIVN | LIVANOVA PLC | 0.00129% | 6,000 | $314,280 | | No Change | $52.38 | 13F |
| COR | CENCORA INC | 0.00128% | 1,000 | $312,530 | | No Change | $312.53 | 13F |
| CAPR | CAPRICOR THERAPEUTICS INC | 0.00121% | 41,000 | $295,610 | | No Change | $7.21 | 13F |
| TVTX | TRAVERE THERAPEUTICS INC | 0.00117% | 12,000 | $286,800 | | No Change | $23.9 | 13F |
| MRUS | MERUS N V | 0.00116% | 3,000 | $282,450 | 3,000 | New | $94.15 | 13F |
| ASND | ASCENDIS PHARMA A/S | 0.00114% | 1,400 | $278,334 | | No Change | $198.81 | 13F |
| GRFS | GRIFOLS S A | 0.00114% | 28,000 | $278,880 | | No Change | $9.96 | 13F |
| SBRA | SABRA HEALTH CARE REIT INC | 0.00107% | 14,000 | $260,960 | | No Change | $18.64 | 13F |
| SRRK | SCHOLAR ROCK HLDG CORP | 0.00107% | 7,000 | $260,680 | | No Change | $37.24 | 13F |
| NUVL | NUVALENT INC | 0.00106% | 3,000 | $259,440 | -147,000 | -98% | $86.48 | 13F |
| MMSI | MERIT MED SYS INC | 0.00102% | 3,000 | $249,690 | | No Change | $83.23 | 13F |
| COGT | COGENT BIOSCIENCES INC | 0.001% | 17,000 | $244,120 | | No Change | $14.36 | 13F |
| VCYT | VERACYTE INC | 0.00098% | 7,000 | $240,310 | 7,000 | New | $34.33 | 13F |
| GMED | GLOBUS MED INC | 0.00094% | 4,000 | $229,080 | -206,000 | -98.1% | $57.27 | 13F |
| ANNAW | ALEANNA INC | 0.00092% | 990,000 | $225,720 | | No Change | $0.23 | 13F |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 0.00092% | 3,000 | $225,300 | -1,319,000 | -99.77% | $75.1 | 13F |
| MIRM | MIRUM PHARMACEUTICALS INC | 0.0009% | 3,000 | $219,930 | 3,000 | New | $73.31 | 13F |
| URGN | UROGEN PHARMA LTD | 0.0009% | 11,000 | $219,450 | 11,000 | New | $19.95 | 13F |
| HR | HEALTHCARE RLTY TR | 0.00089% | 12,000 | $216,360 | | No Change | $18.03 | 13F |
| TWST | TWIST BIOSCIENCE CORP | 0.00088% | 7,650 | $215,271 | | No Change | $28.14 | 13F |
| GKOS | GLAUKOS CORP | 0.00087% | 2,600 | $212,030 | | No Change | $81.55 | 13F |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 0.00086% | 7,000 | $210,560 | -891,000 | -99.22% | $30.08 | 13F |
| ICLR | ICON PLC | 0.00086% | 1,200 | $210,000 | 1,200 | New | $175 | 13F |
| IMVT | IMMUNOVANT INC | 0.00079% | 12,000 | $193,440 | | No Change | $16.12 | 13F |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 0.00075% | 24,000 | $182,160 | 24,000 | New | $7.59 | 13F |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 0.00071% | 135,000 | $172,800 | | No Change | $1.28 | 13F |
| SLDPW | SOLID POWER INC | 0.00069% | 405,316 | $168,409 | | No Change | $0.42 | 13F |
| SNDX | SYNDAX PHARMACEUTICALS INC | 0.00063% | 10,000 | $153,850 | | No Change | $15.39 | 13F |
| BGLWW | BLUE GOLD LTD | 0.00056% | 300,000 | $137,280 | 300,000 | New | $0.46 | 13F |
| FOLD | AMICUS THERAPEUTICS INC | 0.00052% | 16,000 | $126,080 | | No Change | $7.88 | 13F |
| ARDX | ARDELYX INC | 0.00052% | 23,000 | $126,730 | | No Change | $5.51 | 13F |
| DYN | DYNE THERAPEUTICS INC | 0.00052% | 10,000 | $126,500 | | No Change | $12.65 | 13F |
| EVH | EVOLENT HEALTH INC | 0.00048% | 14,000 | $118,440 | | No Change | $8.46 | 13F |
| ALT | ALTIMMUNE INC | 0.00043% | 27,600 | $104,052 | | No Change | $3.77 | 13F |
| ANNA | ALEANNA INC | 0.00025% | 78,400 | $61,819 | | No Change | $0.79 | 13F |
| CCCC | C4 THERAPEUTICS INC | 0.00025% | 28,000 | $62,160 | | No Change | $2.22 | 13F |
| GERN | GERON CORP | 0.00024% | 43,000 | $58,910 | | No Change | $1.37 | 13F |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 0.00023% | 26,000 | $56,420 | | No Change | $2.17 | 13F |
| CGC | CANOPY GROWTH CORP | 0.00018% | 30,000 | $43,800 | | No Change | $1.46 | 13F |
| BYND | BEYOND MEAT INC | 0.00015% | 19,000 | $35,910 | 19,000 | New | $1.89 | 13F |
| RVMDW | REVOLUTION MEDICINES INC | 0.00015% | 120,085 | $36,026 | | No Change | $0.3 | 13F |
| NVNIW | NVNI GROUP LIMITED | 0.00011% | 375,000 | $27,000 | | No Change | $0.07 | 13F |
| IRWD | IRONWOOD PHARMACEUTICALS INC | 0.00007% | 13,000 | $17,030 | | No Change | $1.31 | 13F |
| ABT | ABBOTT LABS | | | | -136,000 | Exited | | 13F |
| AKRO | AKERO THERAPEUTICS INC | | | | -4,000 | Exited | | 13F |
| AMED | AMEDISYS INC | | | | -575,000 | Exited | | 13F |
| ANSS | ANSYS INC | | | | -997,128 | Exited | | 13F |
| AZEK | AZEK CO INC | | | | -3,141,400 | Exited | | 13F |
| BDSX | BIODESIX INC | | | | -128,000 | Exited | | 13F |
| BRKR | BRUKER CORP | | | | -5,000 | Exited | | 13F |
| CHX | CHAMPIONX CORPORATION | | | | -4,245,000 | Exited | | 13F |
| YMM | FULL TRUCK ALLIANCE CO LTD | | | | -1,550,598 | Exited | | 13F |
| HES | HESS CORP | | | | -5,805,000 | Exited | | 13F |
| JANX | JANUX THERAPEUTICS INC | | | | -48,000 | Exited | | 13F |
| JD | JD.COM INC (PRN) | | | | -40,000,000 | Exited | | 13F |
| LTM | LATAM AIRLINES GROUP SA | | | | -318,092 | Exited | | 13F |
| LBRDA | LIBERTY BROADBAND CORP | | | | -58,215 | Exited | | 13F |
| LBRDK | LIBERTY BROADBAND CORP | | | | -4,274,445 | Exited | | 13F |
| BYND | BEYOND MEAT INC | | | | -19,000 | Exited | | 13F |
| SPY | SPDR S&P 500 ETF TR | | | | -5,500,000 | Exited | | 13F |
| SAGE | SAGE THERAPEUTICS INC | | | | -42,800 | Exited | | 13F |
| SWTX | SPRINGWORKS THERAPEUTICS INC | | | | -5,000 | Exited | | 13F |
| THRD | THIRD HARMONIC BIO INC | | | | -15,361 | Exited | | 13F |
| UTHR | UNITED THERAPEUTICS CORP DEL | | | | -1,000 | Exited | | 13F |
| VRNA | VERONA PHARMA PLC | | | | -1,810,000 | Exited | | 13F |
| VERV | VERVE THERAPEUTICS INC | | | | -3,612,000 | Exited | | 13F |
| PARA | PARAMOUNT GLOBAL | | | | -1,346,151 | Exited | | 13F |
| VYGR | VOYAGER THERAPEUTICS INC | | | | -715,000 | Exited | | 13F |
| HLXB | HELIX ACQUISITION CORP II | | | | -600,000 | Exited | | 13F |
