| SPY | SPDR S&P 500 ETF TR | 14.66% | 5,500,000 | $3,398,175,000 | 5,500,000 | New | $617.85 | 13F |
| HYG | ISHARES TR (Put) | 6.26% | 18,000,000 | $1,451,700,000 | 18,000,000 | New | $80.65 | 13F |
| MSFT | MICROSOFT CORP | 3.75% | 1,747,835 | $869,390,607 | -538,000 | -23.54% | $497.41 | 13F |
| NTRA | NATERA INC | 3.51% | 4,821,809 | $814,596,412 | 274,000 | 6.02% | $168.94 | 13F |
| HES | HESS CORP | 3.47% | 5,805,000 | $804,224,700 | 380,000 | 7% | $138.54 | 13F |
| AON | AON PLC | 3.06% | 1,986,417 | $708,674,129 | 624,673 | 45.87% | $356.76 | 13F |
| EXEL | EXELIXIS INC | 3.05% | 16,035,500 | $706,764,663 | -6,498,000 | -28.84% | $44.08 | 13F |
| AMZN | AMAZON COM INC | 2.87% | 3,034,600 | $665,760,894 | 3,034,600 | New | $219.39 | 13F |
| IQV | IQVIA HLDGS INC | 2.62% | 3,851,351 | $606,934,404 | 439,500 | 12.88% | $157.59 | 13F |
| DIS | DISNEY WALT CO | 2.61% | 4,874,268 | $604,457,975 | -621,955 | -11.32% | $124.01 | 13F |
| CRM | SALESFORCE INC | 2.48% | 2,109,110 | $575,133,206 | 142,000 | 7.22% | $272.69 | 13F |
| TMO | THERMO FISHER SCIENTIFIC INC | 2.42% | 1,383,241 | $560,848,896 | 347,385 | 33.54% | $405.46 | 13F |
| LNTH | LANTHEUS HLDGS INC | 2.37% | 6,722,227 | $550,281,502 | 699,000 | 11.61% | $81.86 | 13F |
| ARMK | ARAMARK | 2.33% | 12,899,701 | $540,110,481 | -3,342,295 | -20.58% | $41.87 | 13F |
| ADSK | AUTODESK INC | 2.33% | 1,744,652 | $540,091,920 | -252,748 | -12.65% | $309.57 | 13F |
| RVMD | REVOLUTION MEDICINES INC | 2.27% | 14,325,692 | $527,042,209 | 791,000 | 5.84% | $36.79 | 13F |
| UNH | UNITEDHEALTH GROUP INC | 2.18% | 1,617,300 | $504,549,081 | 119,400 | 7.97% | $311.97 | 13F |
| TRU | TRANSUNION | 2.05% | 5,404,575 | $475,602,600 | -8,631 | -0.16% | $88 | 13F |
| IBIT | ISHARES BITCOIN TRUST ETF | 1.85% | 7,020,050 | $429,697,261 | 1,226,250 | 21.16% | $61.21 | 13F |
| BSX | BOSTON SCIENTIFIC CORP | 1.84% | 3,981,057 | $427,605,332 | 218,300 | 5.8% | $107.41 | 13F |
| INTU | INTUIT | 1.82% | 536,658 | $422,687,941 | -303,600 | -36.13% | $787.63 | 13F |
| RSP | INVESCO EXCHANGE TRADED FD T (Put) | 1.8% | 2,300,000 | $418,002,000 | 2,300,000 | New | $181.74 | 13F |
| HIMS | HIMS & HERS HEALTH INC | 1.77% | 8,213,581 | $409,447,013 | 259,876 | 3.27% | $49.85 | 13F |
| NDAQ | NASDAQ INC | 1.58% | 4,083,743 | $365,168,299 | -376,545 | -8.44% | $89.42 | 13F |
| SCHW | SCHWAB CHARLES CORP | 1.56% | 3,959,057 | $361,224,361 | 126,200 | 3.29% | $91.24 | 13F |
| ANSS | ANSYS INC | 1.51% | 997,128 | $350,211,296 | 49,128 | 5.18% | $351.22 | 13F |
| BBIO | BRIDGEBIO PHARMA INC | 1.47% | 7,900,000 | $341,122,000 | 2,169,000 | 37.85% | $43.18 | 13F |
| PTGX | PROTAGONIST THERAPEUTICS INC | 1.47% | 6,172,006 | $341,126,772 | 65,000 | 1.06% | $55.27 | 13F |
| GOOG | ALPHABET INC | 1.35% | 1,761,840 | $312,532,798 | 95,800 | 5.75% | $177.39 | 13F |
| NYT | NEW YORK TIMES CO | 1.35% | 5,609,546 | $314,022,385 | -3,322,567 | -37.2% | $55.98 | 13F |
| ADI | ANALOG DEVICES INC | 1.31% | 1,272,200 | $302,809,044 | -54,800 | -4.13% | $238.02 | 13F |
| CBRE | CBRE GROUP INC | 1.28% | 2,113,138 | $296,092,897 | -382,562 | -15.33% | $140.12 | 13F |
| WAB | WABTEC | 1.18% | 1,308,198 | $273,871,251 | -299,900 | -18.65% | $209.35 | 13F |
| MCK | MCKESSON CORP | 0.99% | 314,600 | $230,532,588 | -237,900 | -43.06% | $732.78 | 13F |
| WWD | WOODWARD INC | 0.97% | 914,673 | $224,177,206 | -505,027 | -35.57% | $245.09 | 13F |
| AGIO | AGIOS PHARMACEUTICALS INC | 0.83% | 5,767,466 | $191,825,919 | 67,000 | 1.18% | $33.26 | 13F |
| AZEK | AZEK CO INC | 0.74% | 3,141,400 | $170,735,090 | 2,001,400 | 175.56% | $54.35 | 13F |
| VRNA | VERONA PHARMA PLC | 0.74% | 1,810,000 | $171,189,800 | 725,011 | 66.82% | $94.58 | 13F |
| BEAM | BEAM THERAPEUTICS INC | 0.73% | 10,013,111 | $170,323,018 | 85,000 | 0.86% | $17.01 | 13F |
| CRNX | CRINETICS PHARMACEUTICALS IN | 0.58% | 4,646,098 | $133,621,778 | 41,000 | 0.89% | $28.76 | 13F |
| V | VISA INC | 0.47% | 308,810 | $109,642,991 | -165,400 | -34.88% | $355.05 | 13F |
| CHX | CHAMPIONX CORPORATION | 0.45% | 4,245,000 | $105,445,800 | 1,340,000 | 46.13% | $24.84 | 13F |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 0.42% | 1,322,000 | $97,920,540 | 785,000 | 146.18% | $74.07 | 13F |
| THC | TENET HEALTHCARE CORP | 0.4% | 529,000 | $93,104,000 | 529,000 | New | $176 | 13F |
| EHC | ENCOMPASS HEALTH CORP | 0.37% | 708,000 | $86,822,040 | 89,000 | 14.38% | $122.63 | 13F |
| MA | MASTERCARD INCORPORATED | 0.37% | 152,071 | $85,454,778 | -49,300 | -24.48% | $561.94 | 13F |
| CAH | CARDINAL HEALTH INC | 0.33% | 454,000 | $76,272,000 | 181,000 | 66.3% | $168 | 13F |
| EDU | NEW ORIENTAL ED & TECHNOLOGY | 0.27% | 1,155,150 | $62,320,343 | -150,000 | -11.49% | $53.95 | 13F |
| BBNX | BETA BIONICS INC | 0.26% | 4,203,920 | $61,209,075 | 871,700 | 26.16% | $14.56 | 13F |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 0.26% | 4,529,318 | $59,515,239 | 195,000 | 4.5% | $13.14 | 13F |
| LQDA | LIQUIDIA CORPORATION | 0.23% | 4,238,762 | $52,814,975 | 247,806 | 6.21% | $12.46 | 13F |
| FLUT | FLUTTER ENTMT PLC | 0.22% | 181,229 | $51,787,999 | -60,238 | -24.95% | $285.76 | 13F |
| TNGX | TANGO THERAPEUTICS INC | 0.2% | 9,157,000 | $46,883,840 | 4,546,070 | 98.59% | $5.12 | 13F |
| JD | JD.COM INC (PRN) | 0.18% | 40,000,000 | $41,822,000 | 40,000,000 | New | $1.05 | 13F |
| SGRY | SURGERY PARTNERS INC | 0.18% | 1,926,000 | $42,814,980 | 1,926,000 | New | $22.23 | 13F |
| VERV | VERVE THERAPEUTICS INC | 0.18% | 3,612,000 | $40,562,760 | 2,700,000 | 296.05% | $11.23 | 13F |
| JOYY | JOYY INC | 0.17% | 787,906 | $40,112,294 | 7,906 | 1.01% | $50.91 | 13F |
| HQY | HEALTHEQUITY INC | 0.14% | 319,800 | $33,502,248 | -102,000 | -24.18% | $104.76 | 13F |
| OSCR | OSCAR HEALTH INC | 0.14% | 1,476,000 | $31,645,440 | 1,465,000 | 13318.2% | $21.44 | 13F |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 0.14% | 898,000 | $32,651,280 | 898,000 | New | $36.36 | 13F |
| WGS | GENEDX HOLDINGS CORP | 0.13% | 326,677 | $30,155,554 | 23,677 | 7.81% | $92.31 | 13F |
| GRAL | GRAIL INC | 0.11% | 502,000 | $25,812,840 | 502,000 | New | $51.42 | 13F |
| WAY | WAYSTAR HLDG CORP | 0.11% | 613,000 | $25,053,310 | -1,407,000 | -69.65% | $40.87 | 13F |
| SDGR | SCHRODINGER INC | 0.1% | 1,106,000 | $22,252,720 | 1,106,000 | New | $20.12 | 13F |
| VNET | VNET GROUP INC | 0.09% | 2,994,120 | $20,659,428 | 555,000 | 22.75% | $6.9 | 13F |
| ALKS | ALKERMES PLC | 0.09% | 691,663 | $19,788,478 | -698,137 | -50.23% | $28.61 | 13F |
| ABT | ABBOTT LABS | 0.08% | 136,000 | $18,497,360 | -197,000 | -59.16% | $136.01 | 13F |
| YMM | FULL TRUCK ALLIANCE CO LTD | 0.08% | 1,550,598 | $18,312,562 | -5,806,609 | -78.92% | $11.81 | 13F |
| COOP | MR COOPER GROUP INC | 0.08% | 122,500 | $18,278,225 | 122,500 | New | $149.21 | 13F |
| ENTA | ENANTA PHARMACEUTICALS INC | 0.07% | 2,122,262 | $16,044,301 | | No Change | $7.56 | 13F |
| SVRA | SAVARA INC | 0.07% | 6,835,000 | $15,583,800 | | No Change | $2.28 | 13F |
| TECX | TECTONIC THERAPEUTIC INC | 0.07% | 853,050 | $16,950,104 | | No Change | $19.87 | 13F |
| PARA | PARAMOUNT GLOBAL | 0.07% | 1,346,151 | $17,365,348 | 1,346,151 | New | $12.9 | 13F |
| LTM | LATAM AIRLINES GROUP SA | 0.06% | 318,092 | $12,927,259 | -243,918 | -43.4% | $40.64 | 13F |
| MARA | MARA HOLDINGS INC | 0.06% | 835,000 | $13,092,800 | | No Change | $15.68 | 13F |
| GMED | GLOBUS MED INC | 0.05% | 210,000 | $12,394,200 | 127,000 | 153.01% | $59.02 | 13F |
| NUVL | NUVALENT INC | 0.05% | 150,000 | $11,445,000 | | No Change | $76.3 | 13F |
| TYRA | TYRA BIOSCIENCES INC | 0.05% | 1,143,818 | $10,946,338 | | No Change | $9.57 | 13F |
| CDTX | CIDARA THERAPEUTICS INC | 0.04% | 200,000 | $9,742,000 | 200,000 | New | $48.71 | 13F |
| HLXB | HELIX ACQUISITION CORP II | 0.03% | 600,000 | $6,390,000 | | No Change | $10.65 | 13F |
| VYGR | VOYAGER THERAPEUTICS INC | 0.00959% | 715,000 | $2,223,650 | -1,855,700 | -72.19% | $3.11 | 13F |
| PRME | PRIME MEDICINE INC | 0.00799% | 750,000 | $1,852,500 | | No Change | $2.47 | 13F |
| ALVO | ALVOTECH | 0.00786% | 199,675 | $1,821,036 | | No Change | $9.12 | 13F |
| SMC | SUMMIT MIDSTREAM CORPORATION | 0.00616% | 58,214 | $1,427,989 | | No Change | $24.53 | 13F |
| JANX | JANUX THERAPEUTICS INC | 0.00478% | 48,000 | $1,108,800 | | No Change | $23.1 | 13F |
| TVRD | TVARDI THERAPEUTICS INC | 0.00435% | 43,225 | $1,008,439 | 43,225 | New | $23.33 | 13F |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 0.00433% | 3,319 | $1,004,462 | | No Change | $302.64 | 13F |
| BTSG | BRIGHTSPRING HEALTH SVCS INC | 0.00224% | 22,000 | $518,980 | | No Change | $23.59 | 13F |
| SLNO | SOLENO THERAPEUTICS INC | 0.00181% | 5,000 | $418,900 | | No Change | $83.78 | 13F |
| AXSM | AXSOME THERAPEUTICS INC | 0.0018% | 4,000 | $417,560 | | No Change | $104.39 | 13F |
| GH | GUARDANT HEALTH INC | 0.0018% | 8,000 | $416,320 | 8,000 | New | $52.04 | 13F |
| ROIV | ROIVANT SCIENCES LTD | 0.0018% | 37,000 | $416,990 | | No Change | $11.27 | 13F |
| CAPR | CAPRICOR THERAPEUTICS INC | 0.00176% | 41,000 | $407,130 | -2,209,400 | -98.18% | $9.93 | 13F |
| PGNY | PROGYNY INC | 0.00171% | 18,000 | $396,000 | | No Change | $22 | 13F |
| SAGE | SAGE THERAPEUTICS INC | 0.00168% | 42,800 | $390,336 | | No Change | $9.12 | 13F |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 0.00157% | 26,000 | $364,520 | | No Change | $14.02 | 13F |
| INSM | INSMED INC | 0.0013% | 3,000 | $301,920 | | No Change | $100.64 | 13F |
| COR | CENCORA INC | 0.00129% | 1,000 | $299,850 | | No Change | $299.85 | 13F |
| UTHR | UNITED THERAPEUTICS CORP DEL | 0.00124% | 1,000 | $287,350 | | No Change | $287.35 | 13F |
| MMSI | MERIT MED SYS INC | 0.00121% | 3,000 | $280,440 | | No Change | $93.48 | 13F |
| TWST | TWIST BIOSCIENCE CORP | 0.00121% | 7,650 | $281,444 | | No Change | $36.79 | 13F |
| KRYS | KRYSTAL BIOTECH INC | 0.00119% | 2,000 | $274,920 | | No Change | $137.46 | 13F |
| LIVN | LIVANOVA PLC | 0.00117% | 6,000 | $270,120 | -31,000 | -83.78% | $45.02 | 13F |
| GKOS | GLAUKOS CORP | 0.00116% | 2,600 | $268,554 | | No Change | $103.29 | 13F |
| ONC | BEONE MEDICINES LTD | 0.00115% | 1,100 | $266,277 | | No Change | $242.07 | 13F |
| ACLX | ARCELLX INC | 0.00114% | 4,000 | $263,400 | | No Change | $65.85 | 13F |
| SBRA | SABRA HEALTH CARE REIT INC | 0.00111% | 14,000 | $258,160 | | No Change | $18.44 | 13F |
| GRFS | GRIFOLS S A | 0.00109% | 28,000 | $253,120 | | No Change | $9.04 | 13F |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 0.00108% | 15,800 | $249,640 | | No Change | $15.8 | 13F |
| SRRK | SCHOLAR ROCK HLDG CORP | 0.00107% | 7,000 | $247,940 | | No Change | $35.42 | 13F |
| ASND | ASCENDIS PHARMA A/S | 0.00104% | 1,400 | $241,640 | | No Change | $172.6 | 13F |
| SWTX | SPRINGWORKS THERAPEUTICS INC | 0.00101% | 5,000 | $234,950 | -113,000 | -95.76% | $46.99 | 13F |
| ANNAW | ALEANNA INC | 0.001% | 990,000 | $232,650 | | No Change | $0.24 | 13F |
| AKRO | AKERO THERAPEUTICS INC | 0.00092% | 4,000 | $213,440 | 4,000 | New | $53.36 | 13F |
| CGON | CG ONCOLOGY INC | 0.0009% | 8,000 | $208,000 | 8,000 | New | $26 | 13F |
| BRKR | BRUKER CORP | 0.00089% | 5,000 | $206,000 | | No Change | $41.2 | 13F |
| QURE | UNIQURE NV | 0.00084% | 14,000 | $195,160 | | No Change | $13.94 | 13F |
| IMVT | IMMUNOVANT INC | 0.00083% | 12,000 | $192,000 | | No Change | $16 | 13F |
| HR | HEALTHCARE RLTY TR | 0.00082% | 12,000 | $190,320 | | No Change | $15.86 | 13F |
| TVTX | TRAVERE THERAPEUTICS INC | 0.00077% | 12,000 | $177,600 | 12,000 | New | $14.8 | 13F |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 0.00072% | 135,000 | $167,400 | | No Change | $1.24 | 13F |
| EVH | EVOLENT HEALTH INC | 0.00068% | 14,000 | $157,640 | | No Change | $11.26 | 13F |
| SLDPW | SOLID POWER INC | 0.00066% | 405,316 | $151,994 | | No Change | $0.38 | 13F |
| COGT | COGENT BIOSCIENCES INC | 0.00053% | 17,000 | $122,060 | | No Change | $7.18 | 13F |
| ALT | ALTIMMUNE INC | 0.00046% | 27,600 | $106,812 | | No Change | $3.87 | 13F |
| NVAX | NOVAVAX INC | 0.00043% | 16,000 | $100,800 | | No Change | $6.3 | 13F |
| DYN | DYNE THERAPEUTICS INC | 0.00041% | 10,000 | $95,200 | | No Change | $9.52 | 13F |
| FOLD | AMICUS THERAPEUTICS INC | 0.0004% | 16,000 | $91,680 | | No Change | $5.73 | 13F |
| SNDX | SYNDAX PHARMACEUTICALS INC | 0.0004% | 10,000 | $93,650 | | No Change | $9.37 | 13F |
| ARDX | ARDELYX INC | 0.00039% | 23,000 | $90,160 | | No Change | $3.92 | 13F |
| THRD | THIRD HARMONIC BIO INC | 0.00036% | 15,361 | $83,410 | 15,361 | New | $5.43 | 13F |
| BYND | BEYOND MEAT INC | 0.00029% | 19,000 | $66,310 | 19,000 | New | $3.49 | 13F |
| GERN | GERON CORP | 0.00026% | 43,000 | $60,630 | | No Change | $1.41 | 13F |
| ANNA | ALEANNA INC | 0.00021% | 78,400 | $49,761 | | No Change | $0.63 | 13F |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 0.00019% | 26,000 | $44,720 | | No Change | $1.72 | 13F |
| CCCC | C4 THERAPEUTICS INC | 0.00017% | 28,000 | $40,040 | | No Change | $1.43 | 13F |
| BDSX | BIODESIX INC | 0.00016% | 128,000 | $36,122 | -1,731,308 | -93.12% | $0.28 | 13F |
| CGC | CANOPY GROWTH CORP | 0.00016% | 30,000 | $36,600 | | No Change | $1.22 | 13F |
| RVMDW | REVOLUTION MEDICINES INC | 0.00014% | 120,085 | $32,423 | | No Change | $0.27 | 13F |
| NVNIW | NVNI GROUP LIMITED | 0.00008% | 375,000 | $19,350 | | No Change | $0.05 | 13F |
| IRWD | IRONWOOD PHARMACEUTICALS INC | 0.00004% | 13,000 | $9,324 | | No Change | $0.72 | 13F |
| BPMC | BLUEPRINT MEDICINES CORP | | | | -4,000 | Exited | | 13F |
| CARA | CARA THERAPEUTICS INC | | | | -129,685 | Exited | | 13F |
| CHE | CHEMED CORP NEW | | | | -400 | Exited | | 13F |
| DFS | DISCOVER FINL SVCS | | | | -4,780,000 | Exited | | 13F |
| ELAN | ELANCO ANIMAL HEALTH INC | | | | -16,000 | Exited | | 13F |
| FBRX | FORTE BIOSCIENCES INC | | | | -70,429 | Exited | | 13F |
| ITCI | INTRA-CELLULAR THERAPIES INC | | | | -3,055,000 | Exited | | 13F |
| IBB | ISHARES TR (Put) | | | | -3,600,000 | Exited | | 13F |
| JNPR | JUNIPER NETWORKS INC | | | | -295,000 | Exited | | 13F |
| A105PS | MARBLEGATE ACQUISITION CORP | | | | -150,000 | Exited | | 13F |
| GATEW | MARBLEGATE ACQUISITION CORP | | | | -1,485,000 | Exited | | 13F |
| RXST | RXSIGHT INC | | | | -175,000 | Exited | | 13F |
| SPY | SPDR S&P 500 ETF TR (Put) | | | | -3,300,000 | Exited | | 13F |
| SRPT | SAREPTA THERAPEUTICS INC | | | | -2,341,424 | Exited | | 13F |
| SIMO | SILICON MOTION TECHNOLOGY CO | | | | -29,298 | Exited | | 13F |
| SGI | SOMNIGROUP INTERNATIONAL INC | | | | -1,326,242 | Exited | | 13F |
| TMDX | TRANSMEDICS GROUP INC | | | | -3,000 | Exited | | 13F |
| X | UNITED STATES STL CORP NEW | | | | -2,135,000 | Exited | | 13F |
| ZYME | ZYMEWORKS INC | | | | -400,000 | Exited | | 13F |
| BYND | BEYOND MEAT INC | | | | -19,000 | Exited | | 13F |
| BHVN | BIOHAVEN LTD | | | | -4,813,167 | Exited | | 13F |
