| SPY | SPDR S&P 500 ETF TR (Put) | 10.29% | 3,300,000 | $1,845,987,000 | -850,000 | -20.48% | $559.39 | 13F |
| MSFT | MICROSOFT CORP | 4.78% | 2,285,835 | $858,079,601 | 652,688 | 39.97% | $375.39 | 13F |
| EXEL | EXELIXIS INC | 4.64% | 22,533,500 | $831,936,820 | -906,000 | -3.87% | $36.92 | 13F |
| UNH | UNITEDHEALTH GROUP INC | 4.37% | 1,497,900 | $784,525,125 | 35,400 | 2.42% | $523.75 | 13F |
| NTRA | NATERA INC | 3.59% | 4,547,809 | $643,105,671 | 116,200 | 2.62% | $141.41 | 13F |
| IQV | IQVIA HLDGS INC | 3.35% | 3,411,851 | $601,509,331 | 288,700 | 9.24% | $176.3 | 13F |
| LNTH | LANTHEUS HLDGS INC | 3.28% | 6,023,227 | $587,866,955 | 707,000 | 13.3% | $97.6 | 13F |
| ARMK | ARAMARK | 3.13% | 16,241,996 | $560,673,702 | 4,831,656 | 42.34% | $34.52 | 13F |
| DIS | DISNEY WALT CO | 3.02% | 5,496,223 | $542,477,210 | 1,068,155 | 24.12% | $98.7 | 13F |
| CRM | SALESFORCE INC | 2.94% | 1,967,110 | $527,893,640 | 756,972 | 62.55% | $268.36 | 13F |
| ADSK | AUTODESK INC | 2.92% | 1,997,400 | $522,919,320 | 155,600 | 8.45% | $261.8 | 13F |
| INTU | INTUIT | 2.88% | 840,258 | $515,910,009 | 86,500 | 11.48% | $613.99 | 13F |
| TMO | THERMO FISHER SCIENTIFIC INC | 2.87% | 1,035,856 | $515,441,946 | -197,400 | -16.01% | $497.6 | 13F |
| RVMD | REVOLUTION MEDICINES INC | 2.67% | 13,534,692 | $478,586,709 | 286,000 | 2.16% | $35.36 | 13F |
| IBB | ISHARES TR (Put) | 2.57% | 3,600,000 | $460,440,000 | | No Change | $127.9 | 13F |
| TRU | TRANSUNION | 2.5% | 5,413,206 | $449,241,966 | 86,887 | 1.63% | $82.99 | 13F |
| NYT | NEW YORK TIMES CO | 2.47% | 8,932,113 | $443,032,805 | 1,556,000 | 21.1% | $49.6 | 13F |
| ITCI | INTRA-CELLULAR THERAPIES INC | 2.25% | 3,055,000 | $403,015,600 | 3,055,000 | New | $131.92 | 13F |
| BSX | BOSTON SCIENTIFIC CORP | 2.12% | 3,762,757 | $379,586,926 | -1,260,200 | -25.09% | $100.88 | 13F |
| AON | AON PLC | 2.11% | 1,361,744 | $378,337,320 | -470,989 | -25.7% | $277.83 | 13F |
| MCK | MCKESSON CORP | 2.07% | 552,500 | $371,826,975 | -58,200 | -9.53% | $672.99 | 13F |
| NDAQ | NASDAQ INC | 1.89% | 4,460,288 | $338,357,448 | 462,269 | 11.56% | $75.86 | 13F |
| CBRE | CBRE GROUP INC | 1.82% | 2,495,700 | $326,387,646 | 315,900 | 14.49% | $130.78 | 13F |
| SCHW | SCHWAB CHARLES CORP | 1.67% | 3,832,857 | $300,036,046 | 663,857 | 20.95% | $78.28 | 13F |
| PTGX | PROTAGONIST THERAPEUTICS INC | 1.65% | 6,107,006 | $295,334,810 | 177,000 | 2.98% | $48.36 | 13F |
| WAB | WABTEC | 1.63% | 1,608,098 | $291,628,572 | 177,900 | 12.44% | $181.35 | 13F |
| IBIT | ISHARES BITCOIN TRUST ETF | 1.51% | 5,793,800 | $271,207,778 | -1,465,300 | -20.19% | $46.81 | 13F |
| ADI | ANALOG DEVICES INC | 1.49% | 1,327,000 | $267,616,090 | 169,800 | 14.67% | $201.67 | 13F |
| GOOG | ALPHABET INC | 1.45% | 1,666,040 | $260,285,429 | -414,500 | -19.92% | $156.23 | 13F |
| WWD | WOODWARD INC | 1.44% | 1,419,700 | $259,081,053 | -101,600 | -6.68% | $182.49 | 13F |
| HIMS | HIMS & HERS HEALTH INC | 1.31% | 7,953,705 | $235,031,983 | -423,295 | -5.05% | $29.55 | 13F |
| BBIO | BRIDGEBIO PHARMA INC | 1.1% | 5,731,000 | $198,120,670 | 1,536,000 | 36.62% | $34.57 | 13F |
| BEAM | BEAM THERAPEUTICS INC | 1.08% | 9,928,111 | $193,896,008 | 1,688,988 | 20.5% | $19.53 | 13F |
| AGIO | AGIOS PHARMACEUTICALS INC | 0.93% | 5,700,466 | $167,023,654 | 26,000 | 0.46% | $29.3 | 13F |
| V | VISA INC | 0.93% | 474,210 | $166,191,637 | -75,300 | -13.7% | $350.46 | 13F |
| CRNX | CRINETICS PHARMACEUTICALS IN | 0.86% | 4,605,098 | $154,454,987 | 530,000 | 13.01% | $33.54 | 13F |
| SRPT | SAREPTA THERAPEUTICS INC | 0.83% | 2,341,424 | $149,429,680 | -523,676 | -18.28% | $63.82 | 13F |
| BHVN | BIOHAVEN LTD | 0.65% | 4,813,167 | $115,708,535 | 385,000 | 8.69% | $24.04 | 13F |
| MA | MASTERCARD INCORPORATED | 0.62% | 201,371 | $110,375,473 | -94,300 | -31.89% | $548.12 | 13F |
| YMM | FULL TRUCK ALLIANCE CO LTD | 0.52% | 7,357,207 | $93,951,533 | -9,227,888 | -55.64% | $12.77 | 13F |
| SGI | SOMNIGROUP INTERNATIONAL INC | 0.44% | 1,326,242 | $79,415,371 | 1,326,242 | New | $59.88 | 13F |
| WAY | WAYSTAR HLDG CORP | 0.42% | 2,020,000 | $75,467,200 | 678,000 | 50.52% | $37.36 | 13F |
| VRNA | VERONA PHARMA PLC | 0.38% | 1,084,989 | $68,885,952 | 1,084,989 | New | $63.49 | 13F |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 0.35% | 4,334,318 | $62,327,493 | 835,609 | 23.88% | $14.38 | 13F |
| EHC | ENCOMPASS HEALTH CORP | 0.35% | 619,000 | $62,692,320 | 158,000 | 34.27% | $101.28 | 13F |
| EDU | NEW ORIENTAL ED & TECHNOLOGY | 0.35% | 1,305,150 | $62,399,222 | -1,054,000 | -44.68% | $47.81 | 13F |
| LQDA | LIQUIDIA CORPORATION | 0.33% | 3,990,956 | $58,866,601 | 700,000 | 21.27% | $14.75 | 13F |
| FLUT | FLUTTER ENTMT PLC | 0.3% | 241,467 | $53,497,014 | 151,167 | 167.41% | $221.55 | 13F |
| ALKS | ALKERMES PLC | 0.26% | 1,389,800 | $45,891,196 | 1,389,800 | New | $33.02 | 13F |
| ABT | ABBOTT LABS | 0.25% | 333,000 | $44,172,450 | 333,000 | New | $132.65 | 13F |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 0.24% | 537,000 | $43,341,270 | 413,000 | 333.06% | $80.71 | 13F |
| BBNX | BETA BIONICS INC | 0.23% | 3,332,220 | $40,786,373 | 3,332,220 | New | $12.24 | 13F |
| CAH | CARDINAL HEALTH INC | 0.21% | 273,000 | $37,611,210 | 273,000 | New | $137.77 | 13F |
| HQY | HEALTHEQUITY INC | 0.21% | 421,800 | $37,274,466 | 419,000 | 14964.3% | $88.37 | 13F |
| JOYY | JOYY INC | 0.18% | 780,000 | $32,744,400 | 780,000 | New | $41.98 | 13F |
| WGS | GENEDX HOLDINGS CORP | 0.15% | 303,000 | $26,835,195 | 108,000 | 55.38% | $88.57 | 13F |
| CAPR | CAPRICOR THERAPEUTICS INC | 0.12% | 2,250,400 | $21,356,296 | | No Change | $9.49 | 13F |
| SVRA | SAVARA INC | 0.11% | 6,835,000 | $18,932,950 | | No Change | $2.77 | 13F |
| VNET | VNET GROUP INC | 0.11% | 2,439,120 | $20,000,784 | 1,789,120 | 275.25% | $8.2 | 13F |
| LTM | LATAM AIRLINES GROUP SA | 0.1% | 562,010 | $17,579,673 | -56,459 | -9.13% | $31.28 | 13F |
| TECX | TECTONIC THERAPEUTIC INC | 0.08% | 853,050 | $15,107,516 | 140,000 | 19.63% | $17.71 | 13F |
| ENTA | ENANTA PHARMACEUTICALS INC | 0.07% | 2,122,262 | $11,714,886 | 14,000 | 0.66% | $5.52 | 13F |
| NUVL | NUVALENT INC | 0.06% | 150,000 | $10,638,000 | | No Change | $70.92 | 13F |
| TYRA | TYRA BIOSCIENCES INC | 0.06% | 1,143,818 | $10,637,507 | 142,837 | 14.27% | $9.3 | 13F |
| MARA | MARA HOLDINGS INC | 0.05% | 835,000 | $9,602,500 | 280,000 | 50.45% | $11.5 | 13F |
| VYGR | VOYAGER THERAPEUTICS INC | 0.05% | 2,570,700 | $8,688,966 | | No Change | $3.38 | 13F |
| TNGX | TANGO THERAPEUTICS INC | 0.04% | 4,610,930 | $6,316,974 | 610,930 | 15.27% | $1.37 | 13F |
| HLXB | HELIX ACQUISITION CORP II | 0.04% | 600,000 | $6,780,000 | | No Change | $11.3 | 13F |
| GMED | GLOBUS MED INC | 0.03% | 83,000 | $6,075,600 | 79,400 | 2205.56% | $73.2 | 13F |
| SWTX | SPRINGWORKS THERAPEUTICS INC | 0.03% | 118,000 | $5,207,340 | 118,000 | New | $44.13 | 13F |
| ZYME | ZYMEWORKS INC | 0.03% | 400,000 | $4,764,000 | -929,974 | -69.92% | $11.91 | 13F |
| RXST | RXSIGHT INC | 0.02% | 175,000 | $4,418,750 | 175,000 | New | $25.25 | 13F |
| VERV | VERVE THERAPEUTICS INC | 0.02% | 912,000 | $4,167,840 | 912,000 | New | $4.57 | 13F |
| SMC | SUMMIT MIDSTREAM CORPORATION | 0.01% | 58,214 | $1,972,872 | | No Change | $33.89 | 13F |
| ALVO | ALVOTECH | 0.01% | 199,675 | $1,930,857 | | No Change | $9.67 | 13F |
| A105PS | MARBLEGATE ACQUISITION CORP | 0.00924% | 150,000 | $1,656,930 | | No Change | $11.05 | 13F |
| PRME | PRIME MEDICINE INC | 0.00832% | 750,000 | $1,492,500 | | No Change | $1.99 | 13F |
| SIMO | SILICON MOTION TECHNOLOGY CO | 0.00826% | 29,298 | $1,481,307 | -385,702 | -92.94% | $50.56 | 13F |
| LIVN | LIVANOVA PLC | 0.0081% | 37,000 | $1,453,360 | 37,000 | New | $39.28 | 13F |
| JANX | JANUX THERAPEUTICS INC | 0.00723% | 48,000 | $1,296,000 | | No Change | $27 | 13F |
| BDSX | BIODESIX INC | 0.00648% | 1,859,308 | $1,162,439 | -1,952,118 | -51.22% | $0.63 | 13F |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 0.00613% | 3,319 | $1,099,352 | | No Change | $331.23 | 13F |
| CARA | CARA THERAPEUTICS INC | 0.00367% | 129,685 | $657,503 | | No Change | $5.07 | 13F |
| FBRX | FORTE BIOSCIENCES INC | 0.00305% | 70,429 | $546,529 | 35,429 | 101.23% | $7.76 | 13F |
| AXSM | AXSOME THERAPEUTICS INC | 0.0026% | 4,000 | $466,520 | | No Change | $116.63 | 13F |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 0.00227% | 26,000 | $406,640 | | No Change | $15.64 | 13F |
| PGNY | PROGYNY INC | 0.00224% | 18,000 | $402,120 | | No Change | $22.34 | 13F |
| BTSG | BRIGHTSPRING HEALTH SVCS INC | 0.00222% | 22,000 | $397,980 | | No Change | $18.09 | 13F |
| ROIV | ROIVANT SCIENCES LTD | 0.00208% | 37,000 | $373,330 | | No Change | $10.09 | 13F |
| KRYS | KRYSTAL BIOTECH INC | 0.00201% | 2,000 | $360,600 | | No Change | $180.3 | 13F |
| SLNO | SOLENO THERAPEUTICS INC | 0.00199% | 5,000 | $357,250 | -85,000 | -94.44% | $71.45 | 13F |
| BPMC | BLUEPRINT MEDICINES CORP | 0.00197% | 4,000 | $354,040 | | No Change | $88.51 | 13F |
| SAGE | SAGE THERAPEUTICS INC | 0.0019% | 42,800 | $340,260 | | No Change | $7.95 | 13F |
| MMSI | MERIT MED SYS INC | 0.00177% | 3,000 | $317,130 | | No Change | $105.71 | 13F |
| UTHR | UNITED THERAPEUTICS CORP DEL | 0.00172% | 1,000 | $308,270 | | No Change | $308.27 | 13F |
| ONC | BEIGENE LTD | 0.00167% | 1,100 | $299,387 | | No Change | $272.17 | 13F |
| TWST | TWIST BIOSCIENCE CORP | 0.00167% | 7,650 | $300,339 | | No Change | $39.26 | 13F |
| COR | CENCORA INC | 0.00155% | 1,000 | $278,090 | | No Change | $278.09 | 13F |
| ACLX | ARCELLX INC | 0.00146% | 4,000 | $262,400 | | No Change | $65.6 | 13F |
| GKOS | GLAUKOS CORP | 0.00143% | 2,600 | $255,892 | | No Change | $98.42 | 13F |
| ANNAW | ALEANNA INC | 0.00138% | 990,000 | $247,401 | | No Change | $0.25 | 13F |
| CHE | CHEMED CORP NEW | 0.00137% | 400 | $246,128 | | No Change | $615.32 | 13F |
| SBRA | SABRA HEALTH CARE REIT INC | 0.00136% | 14,000 | $244,580 | | No Change | $17.47 | 13F |
| GATEW | MARBLEGATE ACQUISITION CORP | 0.00132% | 1,485,000 | $237,600 | | No Change | $0.16 | 13F |
| INSM | INSMED INC | 0.00128% | 3,000 | $228,870 | | No Change | $76.29 | 13F |
| SRRK | SCHOLAR ROCK HLDG CORP | 0.00125% | 7,000 | $225,050 | | No Change | $32.15 | 13F |
| ASND | ASCENDIS PHARMA A/S | 0.00122% | 1,400 | $218,204 | 1,400 | New | $155.86 | 13F |
| BRKR | BRUKER CORP | 0.00116% | 5,000 | $208,700 | | No Change | $41.74 | 13F |
| IMVT | IMMUNOVANT INC | 0.00114% | 12,000 | $205,080 | | No Change | $17.09 | 13F |
| HR | HEALTHCARE RLTY TR | 0.00113% | 12,000 | $202,800 | -3,252,000 | -99.63% | $16.9 | 13F |
| TMDX | TRANSMEDICS GROUP INC | 0.00113% | 3,000 | $201,840 | 3,000 | New | $67.28 | 13F |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 0.00112% | 15,800 | $201,292 | -613,000 | -97.49% | $12.74 | 13F |
| GRFS | GRIFOLS S A | 0.00111% | 28,000 | $199,080 | | No Change | $7.11 | 13F |
| ELAN | ELANCO ANIMAL HEALTH INC | 0.00094% | 16,000 | $168,000 | | No Change | $10.5 | 13F |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 0.00089% | 135,000 | $159,300 | | No Change | $1.18 | 13F |
| QURE | UNIQURE NV | 0.00083% | 14,000 | $148,400 | 14,000 | New | $10.6 | 13F |
| OSCR | OSCAR HEALTH INC | 0.0008% | 11,000 | $144,210 | | No Change | $13.11 | 13F |
| ALT | ALTIMMUNE INC | 0.00077% | 27,600 | $138,000 | | No Change | $5 | 13F |
| EVH | EVOLENT HEALTH INC | 0.00074% | 14,000 | $132,580 | | No Change | $9.47 | 13F |
| FOLD | AMICUS THERAPEUTICS INC | 0.00073% | 16,000 | $130,560 | | No Change | $8.16 | 13F |
| SNDX | SYNDAX PHARMACEUTICALS INC | 0.00068% | 10,000 | $122,850 | | No Change | $12.29 | 13F |
| ARDX | ARDELYX INC | 0.00063% | 23,000 | $112,930 | | No Change | $4.91 | 13F |
| DYN | DYNE THERAPEUTICS INC | 0.00058% | 10,000 | $104,600 | -219,121 | -95.64% | $10.46 | 13F |
| COGT | COGENT BIOSCIENCES INC | 0.00057% | 17,000 | $101,830 | | No Change | $5.99 | 13F |
| NVAX | NOVAVAX INC | 0.00057% | 16,000 | $102,560 | | No Change | $6.41 | 13F |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 0.00048% | 26,000 | $86,580 | | No Change | $3.33 | 13F |
| GERN | GERON CORP | 0.00038% | 43,000 | $68,370 | | No Change | $1.59 | 13F |
| SLDPW | SOLID POWER INC | 0.00038% | 405,316 | $68,863 | | No Change | $0.17 | 13F |
| BYND | BEYOND MEAT INC | 0.00032% | 19,000 | $57,950 | 19,000 | New | $3.05 | 13F |
| CCCC | C4 THERAPEUTICS INC | 0.00025% | 28,000 | $44,800 | | No Change | $1.6 | 13F |
| ANNA | ALEANNA INC | 0.0002% | 78,400 | $35,008 | | No Change | $0.45 | 13F |
| CGC | CANOPY GROWTH CORP | 0.00015% | 30,000 | $27,300 | | No Change | $0.91 | 13F |
| IRWD | IRONWOOD PHARMACEUTICALS INC | 0.00011% | 13,000 | $19,110 | | No Change | $1.47 | 13F |
| NVNIW | NVNI GROUP LIMITED | 0.00006% | 375,000 | $10,725 | | No Change | $0.03 | 13F |
| RVMDW | REVOLUTION MEDICINES INC | 0.00003% | 120,085 | $4,563 | | No Change | $0.04 | 13F |
| ABNB | AIRBNB INC | | | | -2,429,200 | Exited | | 13F |
| ALTR | ALTAIR ENGR INC | | | | -282,000 | Exited | | 13F |
| BYND | BEYOND MEAT INC | | | | -19,000 | Exited | | 13F |
| BMY | BRISTOL-MYERS SQUIBB CO | | | | -3,188,000 | Exited | | 13F |
| ASHR | DBX ETF TR (Call) | | | | -1,020,000 | Exited | | 13F |
| EW | EDWARDS LIFESCIENCES CORP | | | | -3,000 | Exited | | 13F |
| ELEV | ELEVATION ONCOLOGY INC | | | | -3,527,482 | Exited | | 13F |
| EDR | ENDEAVOR GROUP HLDGS INC | | | | -1,835,185 | Exited | | 13F |
| GDS | GDS HLDGS LTD | | | | -1,531,133 | Exited | | 13F |
| GXO | GXO LOGISTICS INCORPORATED | | | | -513,400 | Exited | | 13F |
| GRNDWS | GRINDR INC | | | | -540,000 | Exited | | 13F |
| HCA | HCA HEALTHCARE INC | | | | -1,000 | Exited | | 13F |
| HCP | HASHICORP INC | | | | -6,453,000 | Exited | | 13F |
| ICUI | ICU MED INC | | | | -1,400 | Exited | | 13F |
| RSP | INVESCO EXCHANGE TRADED FD T (Put) | | | | -4,400,000 | Exited | | 13F |
| MASI | MASIMO CORP | | | | -397,000 | Exited | | 13F |
| MTTR | MATTERPORT INC | | | | -5,069,100 | Exited | | 13F |
| MRNA | MODERNA INC (Put) | | | | -2,620,800 | Exited | | 13F |
| SPY | SPDR S&P 500 ETF TR | | | | -82,000 | Exited | | 13F |
| ZTO | ZTO EXPRESS CAYMAN INC (PRN) | | | | -54,930,000 | Exited | | 13F |
| CITEW | CARTICA ACQUISITION CORP | | | | -175,000 | Exited | | 13F |
| ICLR | ICON PLC | | | | -1,000 | Exited | | 13F |
| MTAL | MAC COPPER LIMITED | | | | -330,901 | Exited | | 13F |
