| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Mar 13, 2020 | Buy | $18.34 | 100,000 | 1,834,090 | 1,247,676 | Mar 17, 2020, 09:30 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Mar 16, 2020 | Buy | $15.73 | 10,164 | 159,916 | 1,257,840 | Mar 17, 2020, 09:30 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Mar 17, 2020 | Buy | $15.73 | 8,113 | 127,648 | 1,265,953 | Mar 17, 2020, 09:30 PM |
| CYTK | | CYTOKINETICS INC | Partners L. Bvf | 10% Owner | Feb 13, 2020 | Sale | $15.79 | 1,072,030 | 16,923,924 | 3,131,432 | Feb 18, 2020, 06:00 PM |
| MRUS | | Merus N.V. | Partners L. Bvf | 10% Owner | Jan 16, 2020 | Buy | $16.15 | 278,730 | 4,501,489 | 1,804,105 | Jan 21, 2020, 05:21 PM |
| MRUS | | Merus N.V. | Partners L. Bvf | 10% Owner | Jan 13, 2020 | Buy | $14.98 | 83,962 | 1,257,616 | 1,657,663 | Jan 15, 2020, 06:32 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 18, 2019 | ATM/ITM Option Exercise | $22.00 | 472,268 | 10,389,896 | 940,442 | Dec 20, 2019, 07:18 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 19, 2019 | Buy | $22.00 | 373,195 | 8,210,290 | 1,147,676 | Dec 20, 2019, 07:18 PM |
| CYTK | | CYTOKINETICS INC | Partners L. Bvf | 10% Owner | Dec 10, 2019 | Buy | $9.40 | 223,659 | 2,102,395 | 3,557,673 | Dec 12, 2019, 07:49 PM |
| CYTK | | CYTOKINETICS INC | Partners L. Bvf | 10% Owner | Dec 11, 2019 | Buy | $9.52 | 118,413 | 1,126,700 | 3,617,776 | Dec 12, 2019, 07:49 PM |
| PIRS | | PIERIS PHARMACEUTICALS, INC. | Partners L. Bvf | 10% Owner | Sep 06, 2019 | Sale | $4.50 | 50,000 | 224,970 | 2,385,055 | Sep 10, 2019, 06:00 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | May 10, 2019 | Buy | $14.57 | 10,300 | 150,037 | 728,841 | May 14, 2019, 09:01 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | May 13, 2019 | Buy | $14.36 | 3,797 | 54,526 | 732,638 | May 14, 2019, 09:01 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | May 14, 2019 | Buy | $14.74 | 13,816 | 203,664 | 746,454 | May 14, 2019, 09:01 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 17, 2018 | Buy | $14.19 | 25,000 | 354,792 | 718,541 | Dec 19, 2018, 09:26 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 13, 2018 | Buy | $14.41 | 24,253 | 349,525 | 693,541 | Dec 13, 2018, 06:54 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 11, 2018 | Buy | $14.50 | 9,400 | 136,270 | 666,478 | Dec 13, 2018, 06:54 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 12, 2018 | Buy | $14.75 | 2,810 | 41,448 | 669,288 | Dec 13, 2018, 06:54 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 06, 2018 | Buy | $14.80 | 10,927 | 161,698 | 606,982 | Dec 10, 2018, 07:03 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 07, 2018 | Buy | $14.77 | 32,015 | 472,778 | 638,997 | Dec 10, 2018, 07:03 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 10, 2018 | Buy | $14.54 | 18,081 | 262,972 | 657,078 | Dec 10, 2018, 07:03 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Nov 30, 2018 | Buy | $14.85 | 4,823 | 71,615 | 591,078 | Dec 04, 2018, 07:01 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 03, 2018 | Buy | $14.90 | 806 | 12,009 | 591,884 | Dec 04, 2018, 07:01 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Dec 04, 2018 | Buy | $14.99 | 4,171 | 62,515 | 596,055 | Dec 04, 2018, 07:01 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Nov 28, 2018 | Buy | $15.11 | 8,288 | 125,262 | 576,239 | Nov 29, 2018, 05:55 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Nov 29, 2018 | Buy | $14.93 | 10,016 | 149,543 | 586,255 | Nov 29, 2018, 05:55 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Nov 27, 2018 | Buy | $15.24 | 11,396 | 173,680 | 567,951 | Nov 29, 2018, 05:55 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Nov 19, 2018 | Buy | $13.93 | 9,771 | 136,064 | 494,073 | Nov 21, 2018, 05:42 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Nov 20, 2018 | Buy | $13.68 | 37,482 | 512,701 | 531,555 | Nov 21, 2018, 05:42 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Nov 21, 2018 | Buy | $15.00 | 25,000 | 374,892 | 556,555 | Nov 21, 2018, 05:42 PM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Nov 16, 2018 | Buy | $13.82 | 10,849 | 149,986 | 484,302 | Nov 19, 2018, 10:21 AM |
| XOMA | | XOMA Corp | Partners L. Bvf | 10% Owner | Nov 15, 2018 | Buy | $13.31 | 21,141 | 281,361 | 473,453 | Nov 19, 2018, 10:21 AM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Aug 14, 2017 | Buy | $2.70 | 41,344 | 111,778 | 1,663,039 | Aug 16, 2017, 06:55 PM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Aug 15, 2017 | Buy | $2.41 | 18,858 | 45,489 | 1,674,468 | Aug 16, 2017, 06:55 PM |
| CAPS | | Capstone Therapeutics Corp. | Partners L. Bvf | See Explanation of Responses | Jul 14, 2017 | Sale | $0.06 | 242,236 | 14,534 | 1,377,652 | Jul 18, 2017, 07:59 PM |
| CAPS | | Capstone Therapeutics Corp. | Partners L. Bvf | See Explanation of Responses | Jul 14, 2017 | Sale | $0.06 | 3,993,637 | 239,618 | 0 | Jul 18, 2017, 07:59 PM |
| CAPS | | Capstone Therapeutics Corp. | Partners L. Bvf | See Explanation of Responses | Jul 14, 2017 | Sale | $0.06 | 105,713 | 6,343 | 890,487 | Jul 18, 2017, 07:59 PM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Jun 27, 2017 | Buy | $3.04 | 85,461 | 259,468 | 1,635,032 | Jun 30, 2017, 12:00 PM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Jun 27, 2017 | Buy | $4.00 | 85,461 | 341,844 | 1,635,032 | Jun 29, 2017, 06:21 PM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Jun 21, 2017 | Buy | $4.00 | 12,148 | 48,592 | 1,583,712 | Jun 23, 2017, 07:16 PM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Jun 22, 2017 | Buy | $4.00 | 8,263 | 33,052 | 1,588,237 | Jun 23, 2017, 07:16 PM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Jun 19, 2017 | Buy | $3.85 | 3,595 | 13,841 | 1,577,332 | Jun 19, 2017, 07:33 PM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Jun 15, 2017 | Buy | $3.84 | 11,779 | 45,196 | 1,569,268 | Jun 19, 2017, 07:33 PM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Jun 16, 2017 | Buy | $3.85 | 11,034 | 42,481 | 1,575,365 | Jun 19, 2017, 07:33 PM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Jun 06, 2017 | Buy | $3.75 | 150,909 | 565,909 | 1,449,048 | Jun 08, 2017, 06:58 PM |
| XENE | | Xenon Pharmaceuticals Inc. | Partners L. Bvf | 10% Owner | Jun 07, 2017 | Buy | $3.85 | 207,789 | 800,237 | 1,562,494 | Jun 08, 2017, 06:58 PM |
| CAPS | | Capstone Therapeutics Corp. | Partners L. Bvf | 10% Owner | Jul 01, 2014 | Other Acquisition or Disposition | $0.30 | 616,563 | 184,969 | 3,993,637 | Jul 03, 2014, 07:56 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | See Explanation of Responses | Mar 25, 2014 | Sale | $69.95 | 10,203 | 713,734 | 130,175 | Mar 26, 2014, 07:28 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | See Explanation of Responses | Mar 25, 2014 | Sale | $69.95 | 18,019 | 1,260,489 | 230,125 | Mar 26, 2014, 07:28 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | See Explanation of Responses | Mar 24, 2014 | Sale | $70.17 | 18,306 | 1,284,483 | 140,378 | Mar 26, 2014, 07:28 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | See Explanation of Responses | Mar 24, 2014 | Sale | $70.17 | 31,698 | 2,224,163 | 248,144 | Mar 26, 2014, 07:28 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 20, 2014 | Sale | $73.05 | 10,557 | 771,167 | 158,684 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 18, 2014 | Sale | $74.66 | 14,003 | 1,045,409 | 87,520 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 20, 2014 | Sale | $73.05 | 18,615 | 1,359,787 | 279,842 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 19, 2014 | Sale | $73.03 | 5,395 | 394,015 | 169,241 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 20, 2014 | Sale | $73.05 | 112,369 | 8,208,319 | 1,685,344 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 19, 2014 | Sale | $73.03 | 9,464 | 691,187 | 298,457 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 18, 2014 | Sale | $74.66 | 16,331 | 1,219,209 | 174,636 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 20, 2014 | Sale | $73.05 | 5,359 | 391,464 | 79,390 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 19, 2014 | Sale | $73.03 | 57,370 | 4,189,921 | 1,797,713 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 18, 2014 | Sale | $74.66 | 16,915 | 1,262,808 | 307,921 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 19, 2014 | Sale | $73.03 | 2,771 | 202,375 | 84,749 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Feb 18, 2014 | Sale | $74.66 | 153,751 | 11,478,450 | 1,855,083 | Feb 20, 2014, 08:00 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Nov 26, 2013 | Sale | $57.57 | 208,500 | 12,003,345 | 411,271 | Nov 29, 2013, 11:38 AM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Nov 27, 2013 | Sale | $57.07 | 319,005 | 18,207,114 | 2,008,834 | Nov 29, 2013, 11:38 AM |
| RIGL | | RIGEL PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Nov 19, 2013 | Sale | $2.64 | 484,622 | 1,280,274 | 1,123,848 | Nov 20, 2013, 02:13 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Sep 23, 2013 | Sale | $44.50 | 359,023 | 15,976,524 | 530,410 | Sep 25, 2013, 06:54 PM |
| RIGL | | RIGEL PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Jun 07, 2013 | Buy | $3.47 | 32,700 | 113,394 | 1,455,414 | Jun 11, 2013, 05:55 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Jan 23, 2013 | Buy | $19.78 | 39,600 | 783,181 | 2,163,412 | Jan 25, 2013, 05:17 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Dec 14, 2012 | Buy | $18.63 | 5,386 | 100,365 | 2,123,812 | Dec 18, 2012, 04:36 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Dec 06, 2012 | Buy | $17.94 | 50,100 | 898,959 | 2,118,426 | Dec 10, 2012, 04:40 PM |
| TRGT | | TARGACEPT INC | Partners L. Bvf | 10% Owner | Nov 16, 2012 | Buy | $4.00 | 595,000 | 2,379,822 | 2,977,919 | Nov 20, 2012, 04:21 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 31, 2012 | Buy | $14.99 | 4,076 | 61,096 | 741,627 | Nov 19, 2012, 05:24 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 26, 2012 | Buy | $15.26 | 12,515 | 190,926 | 737,551 | Nov 19, 2012, 05:24 PM |
| TRGT | | TARGACEPT INC | Partners L. Bvf | 10% Owner | Nov 14, 2012 | Buy | $4.00 | 1,216,712 | 4,866,848 | 2,599,919 | Nov 19, 2012, 05:21 PM |
| TRGT | | TARGACEPT INC | Partners L. Bvf | 10% Owner | Nov 16, 2012 | Buy | $5.11 | 73,500 | 375,460 | 2,646,619 | Nov 19, 2012, 05:21 PM |
| TRGT | | TARGACEPT INC | Partners L. Bvf | 10% Owner | Nov 07, 2012 | Buy | $4.08 | 23,100 | 94,276 | 1,795,927 | Nov 09, 2012, 04:52 PM |
| TRGT | | TARGACEPT INC | Partners L. Bvf | 10% Owner | Nov 08, 2012 | Buy | $4.01 | 49,329 | 197,651 | 1,827,856 | Nov 09, 2012, 04:52 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 26, 2012 | Buy | $15.26 | 12,515 | 190,926 | 737,551 | Nov 02, 2012, 06:36 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 31, 2012 | Buy | $14.99 | 4,076 | 61,096 | 741,627 | Nov 02, 2012, 06:36 PM |
| TRGT | | TARGACEPT INC | Partners L. Bvf | 10% Owner | Oct 31, 2012 | Buy | $4.06 | 52,000 | 210,896 | 1,738,827 | Nov 02, 2012, 06:35 PM |
| TRGT | | TARGACEPT INC | Partners L. Bvf | 10% Owner | Nov 01, 2012 | Buy | $4.05 | 30,100 | 121,800 | 1,745,527 | Nov 02, 2012, 06:35 PM |
| TRGT | | TARGACEPT INC | Partners L. Bvf | 10% Owner | Nov 02, 2012 | Buy | $4.05 | 57,600 | 233,482 | 1,781,627 | Nov 02, 2012, 06:35 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Nov 18, 2011 | Buy | $11.01 | 72,669 | 799,795 | 1,788,226 | Nov 22, 2011, 04:29 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Nov 21, 2011 | Buy | $10.59 | 98,171 | 1,039,631 | 725,036 | Nov 22, 2011, 04:29 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Nov 21, 2011 | Buy | $10.59 | 340,200 | 3,602,718 | 2,068,326 | Nov 22, 2011, 04:29 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 26, 2011 | Buy | $13.91 | 6,020 | 83,751 | 1,741,800 | Oct 28, 2011, 04:55 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 21, 2011 | Buy | $13.93 | 4,600 | 64,062 | 1,738,000 | Oct 25, 2011, 04:22 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 18, 2011 | Buy | $13.73 | 2,200 | 30,215 | 1,727,400 | Oct 20, 2011, 05:40 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 20, 2011 | Buy | $13.93 | 11,900 | 165,809 | 1,735,000 | Oct 20, 2011, 05:40 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 13, 2011 | Buy | $13.55 | 4,995 | 67,692 | 605,053 | Oct 14, 2011, 04:16 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 13, 2011 | Buy | $13.55 | 17,258 | 233,880 | 1,726,000 | Oct 14, 2011, 04:16 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 12, 2011 | Buy | $13.69 | 53,100 | 726,992 | 1,711,762 | Oct 14, 2011, 04:16 PM |
| NBIX | | NEUROCRINE BIOSCIENCES INC | Partners L. Bvf | 10% Owner | Oct 12, 2011 | Buy | $5.95 | 29,500 | 175,672 | 3,527,700 | Oct 14, 2011, 04:15 PM |
| NBIX | | NEUROCRINE BIOSCIENCES INC | Partners L. Bvf | 10% Owner | Oct 10, 2011 | Buy | $5.59 | 15,800 | 88,289 | 1,230,465 | Oct 12, 2011, 05:11 PM |
| NBIX | | NEUROCRINE BIOSCIENCES INC | Partners L. Bvf | 10% Owner | Oct 10, 2011 | Buy | $5.59 | 44,700 | 249,779 | 3,501,600 | Oct 12, 2011, 05:11 PM |
| NBIX | | NEUROCRINE BIOSCIENCES INC | Partners L. Bvf | 10% Owner | Oct 11, 2011 | Buy | $5.73 | 3,800 | 21,768 | 3,505,400 | Oct 12, 2011, 05:11 PM |
| NBIX | | NEUROCRINE BIOSCIENCES INC | Partners L. Bvf | 10% Owner | Oct 10, 2011 | Buy | $5.59 | 9,600 | 53,644 | 756,600 | Oct 12, 2011, 05:11 PM |
| LGND | | LIGAND PHARMACEUTICALS INC | Partners L. Bvf | 10% Owner | Oct 04, 2011 | Buy | $12.78 | 14,400 | 183,961 | 1,675,562 | Oct 06, 2011, 05:02 PM |
| CAPS | | Capstone Therapeutics Corp. | Partners L. Bvf | 10% Owner | Sep 06, 2011 | Buy | $0.26 | 312,900 | 81,041 | 4,610,200 | Sep 08, 2011, 04:26 PM |
