| Symbol | Company | Owner | Relationship | Date | Transaction | Cost | # Shares | Value ($) | Total Shares | Filing | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| OPK | Opko Health, Inc. | John A. Paganelli | Director | Dec 14, 2016 | Gift | - | 500 | - | 325,208 | Dec 15, 2016, 04:15 PM | |
| OPK | Opko Health, Inc. | John A. Paganelli | Director | Dec 09, 2016 | Gift | - | 4,000 | - | 325,708 | Dec 12, 2016, 04:29 PM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Dec 02, 2016 | Buy | $10.49 | 1,000 | 10,488 | 160,377,643 | Dec 05, 2016, 06:08 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Dec 01, 2016 | Buy | $10.27 | 3,800 | 39,035 | 160,376,643 | Dec 02, 2016, 07:46 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 30, 2016 | Buy | $10.40 | 1,800 | 18,720 | 160,372,843 | Dec 01, 2016, 06:07 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 28, 2016 | Buy | $10.61 | 5,600 | 59,411 | 160,371,043 | Nov 29, 2016, 07:37 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 23, 2016 | Buy | $10.09 | 4,300 | 43,387 | 160,365,443 | Nov 25, 2016, 07:06 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 22, 2016 | Buy | $10.28 | 5,400 | 55,523 | 160,361,143 | Nov 23, 2016, 07:04 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 21, 2016 | Buy | $10.41 | 3,600 | 37,468 | 160,355,743 | Nov 22, 2016, 06:43 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 18, 2016 | Buy | $10.38 | 1,800 | 18,692 | 160,352,143 | Nov 21, 2016, 07:09 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 16, 2016 | Buy | $10.13 | 4,300 | 43,565 | 160,350,343 | Nov 17, 2016, 06:07 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 10, 2016 | Buy | $9.49 | 12,800 | 121,511 | 160,344,243 | Nov 14, 2016, 06:23 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 11, 2016 | Buy | $9.24 | 1,800 | 16,632 | 160,346,043 | Nov 14, 2016, 06:23 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 09, 2016 | Buy | $9.33 | 5,400 | 50,382 | 160,331,443 | Nov 10, 2016, 06:06 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 08, 2016 | Buy | $9.22 | 23,100 | 213,054 | 160,326,043 | Nov 09, 2016, 06:01 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 02, 2016 | Buy | $9.48 | 10,000 | 94,845 | 160,302,943 | Nov 03, 2016, 06:19 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Nov 01, 2016 | Buy | $9.49 | 10,000 | 94,878 | 160,292,943 | Nov 02, 2016, 06:13 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 31, 2016 | Buy | $9.43 | 11,800 | 111,279 | 160,282,943 | Nov 01, 2016, 06:10 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 28, 2016 | Buy | $9.46 | 10,000 | 94,566 | 160,271,143 | Oct 31, 2016, 06:23 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 27, 2016 | Buy | $9.36 | 10,000 | 93,568 | 160,261,143 | Oct 28, 2016, 06:17 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 26, 2016 | Buy | $9.27 | 5,600 | 51,939 | 160,251,143 | Oct 27, 2016, 07:03 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 25, 2016 | Buy | $9.38 | 3,600 | 33,750 | 160,245,543 | Oct 26, 2016, 07:57 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 24, 2016 | Buy | $9.49 | 1,800 | 17,091 | 160,241,943 | Oct 25, 2016, 06:05 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 21, 2016 | Buy | $9.38 | 1,800 | 16,884 | 160,240,143 | Oct 24, 2016, 06:06 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 20, 2016 | Buy | $9.26 | 2,700 | 24,989 | 160,238,343 | Oct 21, 2016, 06:04 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 19, 2016 | Buy | $9.26 | 14,700 | 136,131 | 160,235,643 | Oct 20, 2016, 07:49 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 18, 2016 | Buy | $9.29 | 1,800 | 16,722 | 160,220,943 | Oct 19, 2016, 07:45 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 17, 2016 | Buy | $9.34 | 3,600 | 33,641 | 160,219,143 | Oct 18, 2016, 06:05 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 14, 2016 | Buy | $9.48 | 1,800 | 17,064 | 160,215,543 | Oct 17, 2016, 06:01 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 13, 2016 | Buy | $9.52 | 5,400 | 51,432 | 160,213,743 | Oct 14, 2016, 06:17 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 11, 2016 | Buy | $9.78 | 7,200 | 70,431 | 160,208,343 | Oct 12, 2016, 06:07 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 10, 2016 | Buy | $9.91 | 7,200 | 71,319 | 160,201,143 | Oct 11, 2016, 06:02 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 07, 2016 | Buy | $9.79 | 17,600 | 172,277 | 160,193,943 | Oct 11, 2016, 06:02 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 06, 2016 | Buy | $10.53 | 4,200 | 44,242 | 160,176,343 | Oct 07, 2016, 06:06 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Oct 04, 2016 | Buy | $10.57 | 3,600 | 38,056 | 160,172,143 | Oct 05, 2016, 06:10 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 30, 2016 | Buy | $10.54 | 1,800 | 18,971 | 160,168,543 | Oct 03, 2016, 06:00 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 29, 2016 | Buy | $10.67 | 3,600 | 38,418 | 160,166,743 | Sep 30, 2016, 06:03 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 28, 2016 | Buy | $11.01 | 5,400 | 59,448 | 160,163,143 | Sep 29, 2016, 06:30 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 27, 2016 | Buy | $11.16 | 1,800 | 20,086 | 160,157,743 | Sep 28, 2016, 06:17 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 26, 2016 | Buy | $11.04 | 1,800 | 19,880 | 160,155,943 | Sep 27, 2016, 06:02 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 23, 2016 | Buy | $10.95 | 1,800 | 19,709 | 160,154,143 | Sep 26, 2016, 06:07 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 22, 2016 | Buy | $10.63 | 1,800 | 19,131 | 160,152,343 | Sep 23, 2016, 06:04 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 21, 2016 | Buy | $10.46 | 1,800 | 18,828 | 160,150,543 | Sep 22, 2016, 07:27 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 20, 2016 | Buy | $10.36 | 1,800 | 18,648 | 160,148,743 | Sep 21, 2016, 06:26 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 19, 2016 | Buy | $10.18 | 1,800 | 18,324 | 160,146,943 | Sep 20, 2016, 06:52 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 13, 2016 | Buy | $9.95 | 10,000 | 99,530 | 160,145,143 | Sep 14, 2016, 06:05 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 12, 2016 | Buy | $9.79 | 10,000 | 97,869 | 160,135,143 | Sep 13, 2016, 06:04 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 09, 2016 | Buy | $9.87 | 3,600 | 35,535 | 160,125,143 | Sep 12, 2016, 06:06 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Sep 02, 2016 | Buy | $9.28 | 10,000 | 92,800 | 160,121,543 | Sep 06, 2016, 11:00 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 25, 2016 | Buy | $9.06 | 48,400 | 438,293 | 160,111,543 | Aug 26, 2016, 06:26 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 24, 2016 | Buy | $9.24 | 15,000 | 138,586 | 160,063,143 | Aug 25, 2016, 06:26 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 23, 2016 | Buy | $9.53 | 29,000 | 276,464 | 160,048,143 | Aug 24, 2016, 07:31 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 22, 2016 | Buy | $9.76 | 11,800 | 115,214 | 160,019,143 | Aug 23, 2016, 07:06 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 19, 2016 | Buy | $9.82 | 15,000 | 147,236 | 160,007,343 | Aug 22, 2016, 07:09 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 18, 2016 | Buy | $9.87 | 10,000 | 98,717 | 159,992,343 | Aug 19, 2016, 07:23 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 17, 2016 | Buy | $9.90 | 10,000 | 98,953 | 159,982,343 | Aug 18, 2016, 06:07 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 16, 2016 | Buy | $10.02 | 10,000 | 100,183 | 159,972,343 | Aug 17, 2016, 06:29 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 15, 2016 | Buy | $10.07 | 10,000 | 100,665 | 159,962,343 | Aug 16, 2016, 06:23 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 10, 2016 | Buy | $9.98 | 10,000 | 99,763 | 159,952,343 | Aug 11, 2016, 06:29 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 09, 2016 | Buy | $10.21 | 10,000 | 102,140 | 159,942,343 | Aug 10, 2016, 06:28 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Aug 02, 2016 | Buy | $9.88 | 10,000 | 98,802 | 159,932,343 | Aug 03, 2016, 07:21 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jul 27, 2016 | Buy | $9.91 | 10,000 | 99,142 | 159,922,343 | Jul 28, 2016, 06:22 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jul 13, 2016 | Buy | $9.65 | 15,800 | 152,453 | 159,912,343 | Jul 14, 2016, 06:05 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jul 11, 2016 | Buy | $9.82 | 10,000 | 98,182 | 159,896,543 | Jul 12, 2016, 06:18 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 30, 2016 | Buy | $9.27 | 18,000 | 166,844 | 159,886,543 | Jul 01, 2016, 10:34 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 29, 2016 | Buy | $9.24 | 12,800 | 118,303 | 159,868,543 | Jun 30, 2016, 07:11 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 27, 2016 | Buy | $8.88 | 21,000 | 186,383 | 159,855,743 | Jun 28, 2016, 06:55 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 24, 2016 | Buy | $9.40 | 18,000 | 169,245 | 159,834,743 | Jun 27, 2016, 06:46 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 22, 2016 | Buy | $9.42 | 18,000 | 169,581 | 159,816,743 | Jun 23, 2016, 06:31 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 20, 2016 | Buy | $9.19 | 10,000 | 91,892 | 159,798,743 | Jun 21, 2016, 06:49 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 17, 2016 | Buy | $9.07 | 18,000 | 163,231 | 159,788,743 | Jun 20, 2016, 06:02 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 16, 2016 | Buy | $9.23 | 10,000 | 92,335 | 159,770,743 | Jun 17, 2016, 06:14 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 14, 2016 | Buy | $9.01 | 16,000 | 144,177 | 159,760,743 | Jun 15, 2016, 06:13 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 10, 2016 | Buy | $9.36 | 10,000 | 93,579 | 159,744,743 | Jun 13, 2016, 07:31 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 09, 2016 | Buy | $9.74 | 5,000 | 48,677 | 159,734,743 | Jun 10, 2016, 06:17 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 08, 2016 | Buy | $9.80 | 11,200 | 109,752 | 159,729,743 | Jun 09, 2016, 06:18 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 07, 2016 | Buy | $9.90 | 5,000 | 49,498 | 159,718,543 | Jun 08, 2016, 06:53 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 06, 2016 | Buy | $9.97 | 17,800 | 177,385 | 159,713,543 | Jun 07, 2016, 06:01 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 03, 2016 | Buy | $10.07 | 18,600 | 187,362 | 159,695,743 | Jun 06, 2016, 06:23 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Jun 01, 2016 | Buy | $10.49 | 10,800 | 113,262 | 159,677,143 | Jun 02, 2016, 06:37 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | May 27, 2016 | Buy | $10.35 | 20,000 | 207,014 | 159,666,343 | May 31, 2016, 06:06 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | May 26, 2016 | Buy | $10.45 | 12,000 | 125,436 | 159,646,343 | May 27, 2016, 06:00 AM | |
| OPK | Opko Health, Inc. | Steven D. Rubin | Executive VP-Administration | May 03, 2016 | Tax Payment (Shares) | $10.34 | 121,156 | 1,252,753 | 5,571,251 | May 17, 2016, 05:08 PM | |
| OPK | Opko Health, Inc. | Robert A. Baron | Director | May 13, 2016 | Sale | $9.83 | 37,500 | 368,491 | 297,604 | May 17, 2016, 04:22 PM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | May 12, 2016 | Buy | $9.56 | 30,600 | 292,656 | 159,634,343 | May 13, 2016, 06:04 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | May 11, 2016 | Buy | $10.05 | 19,400 | 194,980 | 159,603,743 | May 12, 2016, 07:06 AM | |
| OPK | Opko Health, Inc. | Steven D. Rubin | Executive VP-Administration | May 03, 2016 | Tax Payment (Shares) | $10.34 | 134,918 | 1,395,052 | 5,557,489 | May 05, 2016, 05:20 PM | |
| OPK | Opko Health, Inc. | Steven D. Rubin | Executive VP-Administration | May 03, 2016 | Option/RSU Exercise | $1.16 | 250,000 | 290,000 | 5,692,407 | May 05, 2016, 05:20 PM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | May 04, 2016 | Buy | $9.91 | 29,800 | 295,333 | 159,584,343 | May 05, 2016, 06:15 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | May 03, 2016 | Buy | $10.25 | 8,100 | 83,017 | 159,554,543 | May 04, 2016, 06:05 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | May 02, 2016 | Buy | $10.33 | 11,800 | 121,926 | 159,546,443 | May 03, 2016, 06:10 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Apr 29, 2016 | Buy | $10.70 | 10,000 | 107,049 | 159,534,643 | May 02, 2016, 06:06 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Apr 28, 2016 | Buy | $10.83 | 10,000 | 108,325 | 159,524,643 | Apr 29, 2016, 06:31 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Apr 27, 2016 | Buy | $10.95 | 11,800 | 129,157 | 159,514,643 | Apr 28, 2016, 07:01 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Apr 25, 2016 | Buy | $11.12 | 15,000 | 166,735 | 159,502,843 | Apr 26, 2016, 06:50 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Apr 19, 2016 | Buy | $11.00 | 7,400 | 81,373 | 159,487,843 | Apr 20, 2016, 06:50 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Apr 15, 2016 | Buy | $10.78 | 7,600 | 81,926 | 159,480,443 | Apr 18, 2016, 06:44 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Apr 06, 2016 | Buy | $10.61 | 20,000 | 212,157 | 159,472,843 | Apr 07, 2016, 07:10 AM | |
| OPK | Opko Health, Inc. | Phillip Frost, M.D. | CEO & Chairman | Apr 05, 2016 | Buy | $10.28 | 20,000 | 205,646 | 159,452,843 | Apr 06, 2016, 07:21 AM | |
| OPK | Opko Health, Inc. | Thomas E. Beier | Director | Apr 01, 2016 | Option/RSU Exercise | $1.54 | 20,000 | 30,800 | 40,000 | Apr 05, 2016, 04:39 PM |
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