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| Stock | Company | % Portfolio | Shares Held | Market Value | Change in Shares | % Change | Quarter End Price | Source |
|---|---|---|---|---|---|---|---|---|
| SLNO | Soleno Therapeutics Inc | 28.31% | 8,418,093 | $360,294,380 | No Change | $42.8 | 13F | |
| GERN | Geron Corp | 7.06% | 27,225,292 | $89,843,464 | 3,081,611 | 12.76% | $3.3 | 13F |
| HRMY | Harmony Biosciences Holdings Inc | 6.88% | 2,606,247 | $87,517,774 | No Change | $33.58 | 13F | |
| SVA | Sinovac Biotech Ltd. | 6% | 11,800,000 | $76,346,000 | 11,800,000 | New | $6.47 | 13F |
| AVDL | Avadel Pharmaceuticals PLC | 5.27% | 3,972,099 | $67,088,752 | -124,329 | -3.04% | $16.89 | 13F |
| VRNA | Verona Pharma PLC | 4.56% | 3,610,177 | $58,087,748 | -639,741 | -15.05% | $16.09 | 13F |
| ALXO | ALX Oncology Holdings Inc | 3.7% | 4,220,048 | $47,053,535 | No Change | $11.15 | 13F | |
| DYN | Dyne Therapeutics Inc | 3.65% | 1,635,136 | $46,421,511 | 600,000 | 57.96% | $28.39 | 13F |
| TERN | Terns Pharmaceuticals Inc | 3.43% | 6,657,992 | $43,676,428 | No Change | $6.56 | 13F | |
| ATXS | Astria Therapeutics Inc | 2.58% | 2,329,027 | $32,781,055 | -153,700 | -6.19% | $14.07 | 13F |
| VRDN | Viridian Therapeutics Inc | 2.31% | 1,678,207 | $29,385,405 | No Change | $17.51 | 13F | |
| SLN | Silence Therapeutics PLC | 1.88% | 1,105,454 | $23,877,806 | 595,250 | 116.67% | $21.6 | 13F |
| ADVM | Adverum Biotechnologies, Inc. | 1.67% | 1,500,000 | $21,210,000 | 1,500,000 | New | $14.14 | 13F |
| OLMA | Olema Pharmaceuticals Inc | 1.67% | 1,873,704 | $21,210,329 | No Change | $11.32 | 13F | |
| ALPN | Alpine Immune Sciences Inc | 1.63% | 520,505 | $20,794,175 | -298,770 | -36.47% | $39.95 | 13F |
| TARS | Tarsus Pharmaceuticals Inc | 1.62% | 565,550 | $20,557,743 | -1,218,456 | -68.3% | $36.35 | 13F |
| VSTM | Verastem Inc | 1.43% | 1,538,461 | $18,153,840 | No Change | $11.8 | 13F | |
| CRNX | Crinetics Pharmaceuticals Inc | 1.29% | 350,000 | $16,383,500 | No Change | $46.81 | 13F | |
| COGT | Cogent Biosciences Inc | 1.19% | 2,244,941 | $15,086,004 | No Change | $6.72 | 13F | |
| SERA | Sera Prognostics Inc | 1.18% | 1,650,440 | $15,019,004 | No Change | $9.1 | 13F | |
| RGLS | Regulus Therapeutics Inc | 1.13% | 5,000,000 | $14,400,000 | 5,000,000 | New | $2.88 | 13F |
| TRML | Tourmaline Bio Inc. | 1.07% | 591,882 | $13,554,098 | No Change | $22.9 | 13F | |
| CMPS | Compass Pathway PLC | 1.05% | 1,608,000 | $13,378,560 | No Change | $8.32 | 13F | |
| ORIC | Oric Pharmaceuticals Inc | 0.92% | 849,681 | $11,683,114 | No Change | $13.75 | 13F | |
| ENGN | Engene Holdings Inc. | 0.9% | 678,705 | $11,504,050 | No Change | $16.95 | 13F | |
| GTH | Genetron Holdings Ltd | 0.86% | 2,708,056 | $10,899,925 | No Change | $4.02 | 13F | |
| IOBT | IO Biotech Inc | 0.84% | 6,173,439 | $10,680,049 | No Change | $1.73 | 13F | |
| SVRA | Savara Inc | 0.82% | 2,088,323 | $10,399,849 | No Change | $4.98 | 13F | |
| ZLAB | Zai Lab Ltd | 0.67% | 531,198 | $8,509,792 | 119,521 | 29.03% | $16.02 | 13F |
| DCTH | Delcath Systems, Inc. | 0.62% | 1,666,746 | $7,950,378 | 811,555 | 94.9% | $4.77 | 13F |
| RZLT | Rezolute Inc | 0.56% | 2,797,704 | $7,134,145 | -445,138 | -13.73% | $2.55 | 13F |
| CMPX | Compass Therapeutics Inc | 0.55% | 3,556,023 | $7,040,926 | No Change | $1.98 | 13F | |
| TIL | Instil Bio Inc | 0.53% | 624,338 | $6,742,850 | -2 | -0.00032% | $10.8 | 13F |
| QTTB | Q32 Bio Inc. | 0.5% | 370,068 | $6,305,959 | 370,068 | New | $17.04 | 13F |
| BOLT | Bolt Therapeutics Inc | 0.39% | 3,521,291 | $4,929,807 | No Change | $1.4 | 13F | |
| UNCY | Unicycive Therapeutics | 0.38% | 3,470,152 | $4,788,810 | No Change | $1.38 | 13F | |
| ALLK | Allakos Inc | 0.3% | 2,988,000 | $3,764,880 | No Change | $1.26 | 13F | |
| ALGS | Aligos Therapeutics Inc | 0.27% | 3,547,030 | $3,476,089 | No Change | $0.98 | 13F | |
| DBVT | DBV Technologies SA | 0.16% | 2,708,875 | $2,029,218 | No Change | $0.75 | 13F | |
| CDXS | Codexis, Inc | 0.11% | 388,144 | $1,354,623 | No Change | $3.49 | 13F | |
| AADI | Aadi Bioscience Inc | 0.09% | 509,572 | $1,192,398 | No Change | $2.34 | 13F | |
| DTIL | Precision Biosciences Inc | 0.00498% | 4,675 | $63,395 | 4,675 | New | $13.56 | 13F |
| APGE | Apogee Therapeutics Inc | -400,000 | Exited | 13F | ||||
| ARWR | Arrowhead Pharmaceuticals Inc | -137,411 | Exited | 13F | ||||
| GRCL | Gracell Biotechnologies Inc | -9,546,485 | Exited | 13F | ||||
| FIXX | Homology Medicines, Inc. | -370,068 | Exited | 13F | ||||
| ICVX | Icosavax, Inc. | -1,704,568 | Exited | 13F | ||||
| IOVA | Iovance Biotherapeutics Inc | -655,057 | Exited | 13F | ||||
| KALV | KalVista Pharmaceuticals Inc. | -856,008 | Exited | 13F | ||||
| DTIL | Precision Biosciences Inc | -140,255 | Exited | 13F | ||||
| RYZB | Rayzebio Inc | -110,581 | Exited | 13F | ||||
| PHVS | Pharvaris NV | -285,000 | Exited | 13F |