| SPY | STATE STR SPDR S&P 500 ETF T (Put) | 13.75% | 950,000 | $709,431,500 | 600,000 | 171.43% | $746.77 | 13F |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 6.32% | 12,437,000 | $326,098,140 | 110,000 | 0.89% | $26.22 | 13F |
| MANE | Veradermics, Inc | 6.15% | 2,957,937 | $317,238,743 | -1,211,033 | -29.05% | | Form 4 |
| LEGN | LEGEND BIOTECH CORP | 3.96% | 7,070,000 | $204,181,600 | -511,029 | -6.74% | $28.88 | 13F |
| PVLA | PALVELLA THERAPEUTICS INC NE | 3.36% | 1,135,406 | $173,512,745 | -18,090 | -1.57% | $152.82 | 13F |
| AVBP | ARRIVENT BIOPHARMA INC | 3.04% | 4,515,531 | $156,869,547 | 114,448 | 2.6% | $34.74 | 13F |
| BNTC | BENITEC BIOPHARMA INC | 2.99% | 11,548,351 | $154,516,936 | | No Change | $13.38 | 13F |
| BHVN | BIOHAVEN LTD | 2.97% | 10,286,937 | $153,069,623 | | No Change | $14.88 | 13F |
| AMD | ADVANCED MICRO DEVICES INC | 2.90% | 257,240 | $149,433,288 | | No Change | $580.91 | 13F |
| RCUS | ARCUS BIOSCIENCES INC | 2.85% | 4,776,423 | $147,257,121 | -254,570 | -5.06% | $30.83 | 13F |
| TSM | TAIWAN SEMICONDUCTOR MANUFAC | 2.82% | 304,627 | $145,480,716 | 5,920 | 1.98% | $477.57 | 13F |
| NVDA | NVIDIA CORPORATION | 2.79% | 720,609 | $144,186,655 | 145,953 | 25.4% | $200.09 | 13F |
| EYPT | EYEPOINT INC | 2.30% | 8,296,375 | $118,638,163 | | No Change | $14.3 | 13F |
| SYY | SYSCO CORP | 2.29% | 1,411,550 | $117,977,349 | 252,394 | 21.77% | $83.58 | 13F |
| GE | GE AEROSPACE | 2.25% | 310,262 | $115,954,217 | | No Change | $373.73 | 13F |
| IMTX | IMMATICS N.V | 2.20% | 11,190,129 | $113,356,007 | | No Change | $10.13 | 13F |
| MGM | MGM RESORTS INTERNATIONAL | 2.15% | 2,325,360 | $111,175,462 | 166,560 | 7.72% | $47.81 | 13F |
| META | META PLATFORMS INC | 1.92% | 175,807 | $99,030,325 | 6,100 | 3.59% | $563.29 | 13F |
| CAPR | CAPRICOR THERAPEUTICS INC | 1.91% | 4,092,784 | $98,554,239 | 274,184 | 7.18% | $24.08 | 13F |
| KURA | KURA ONCOLOGY INC | 1.82% | 8,575,422 | $94,072,379 | | No Change | $10.97 | 13F |
| GLUE | MONTE ROSA THERAPEUTICS INC | 1.66% | 3,549,539 | $85,898,844 | -677,270 | -16.02% | $24.2 | 13F |
| AVLN | AVALYN PHARMACEUTICALS INC | 1.60% | 2,503,109 | $82,402,348 | 2,503,109 | New | $32.92 | 13F |
| HD | HOME DEPOT INC | 1.54% | 226,053 | $79,724,372 | 4,463 | 2.01% | $352.68 | 13F |
| HUT | HUT 8 CORP | 1.50% | 670,000 | $77,348,150 | 670,000 | New | $115.45 | 13F |
| COF | CAPITAL ONE FINL CORP | 1.29% | 333,098 | $66,826,121 | 30,698 | 10.15% | $200.62 | 13F |
| VMC | VULCAN MATLS CO | 1.23% | 214,978 | $63,420,660 | 33,384 | 18.38% | $295.01 | 13F |
| FERG | FERGUSON ENTERPRISES INC | 1.13% | 246,758 | $58,563,076 | 34,858 | 16.45% | $237.33 | 13F |
| ZURA | ZURA BIO LTD | 1.08% | 9,443,001 | $55,713,706 | 376,000 | 4.15% | $5.9 | 13F |
| IFRX | INFLARX NV | 1.00% | 22,933,910 | $51,371,958 | 15,000,000 | 189.06% | $2.24 | 13F |
| AURA | AURA BIOSCIENCES INC | 0.99% | 7,206,217 | $51,164,141 | 2,833,333 | 64.79% | $7.1 | 13F |
| FTH | FAETH THERAPEUTICS INC | 0.98% | 2,020,103 | $50,502,575 | 1,985,554 | 5747.07% | $25 | 13F |
| MSOS | ADVISORSHARES TR | 0.96% | 9,738,524 | $49,471,702 | 692,324 | 7.65% | $5.08 | 13F |
| AMZN | AMAZON COM INC | 0.95% | 204,860 | $48,826,332 | -49,149 | -19.35% | $238.34 | 13F |
| APH | AMPHENOL CORP | 0.92% | 269,300 | $47,482,976 | 269,300 | New | $176.32 | 13F |
| SPOT | SPOTIFY TECHNOLOGY S A | 0.91% | 101,800 | $46,739,434 | 100,700 | 9154.55% | $459.13 | 13F |
| CTNM | CONTINEUM THERAPEUTICS INC | 0.90% | 2,841,334 | $46,569,464 | | No Change | $16.39 | 13F |
| APO | APOLLO GLOBAL MGMT INC | 0.88% | 383,300 | $45,348,223 | -4,400 | -1.13% | $118.31 | 13F |
| BAC | BANK OF AMER CORP | 0.87% | 789,720 | $44,998,246 | -505,525 | -39.03% | $56.98 | 13F |
| CRNX | CRINETICS PHARMACEUTICALS IN | 0.86% | 1,186,279 | $44,390,560 | 142,400 | 13.64% | $37.42 | 13F |
| DRAM | ROUNDHILL ETF TRUST | 0.86% | 603,000 | $44,531,550 | 603,000 | New | $73.85 | 13F |
| CBRS | CEREBRAS SYSTEMS INC | 0.74% | 171,900 | $37,989,900 | 171,900 | New | $221 | 13F |
| REPL | Replimune Group, Inc. | 0.67% | 6,609,000 | $35,754,690 | 2,219,164 | 50.55% | | 13G |
| DKS | DICKS SPORTING GOODS INC | 0.66% | 151,320 | $34,320,889 | 151,320 | New | $226.81 | 13F |
| AVGO | BROADCOM INC | 0.61% | 83,600 | $31,579,900 | 83,600 | New | $377.75 | 13F |
| CMPX | COMPASS THERAPEUTICS INC | 0.60% | 14,101,159 | $30,881,538 | -206,220 | -1.44% | $2.19 | 13F |
| LXEO | LEXEO THERAPEUTICS INC | 0.58% | 6,384,200 | $29,718,451 | 5,134,200 | 410.74% | $4.66 | 13F |
| UNH | UNITEDHEALTH GROUP INC | 0.52% | 64,130 | $26,654,352 | -36,500 | -36.27% | $415.63 | 13F |
| PROK | PROKIDNEY CORP | 0.49% | 12,341,266 | $25,176,183 | | No Change | $2.04 | 13F |
| WHWK | WHITEHAWK THERAPEUTICS INC | 0.38% | 4,300,000 | $19,694,000 | 600,000 | 16.22% | $4.58 | 13F |
| SPCX | SPACE EXPLORATION TECHN CORP | 0.34% | 101,200 | $17,291,032 | 101,200 | New | $170.86 | 13F |
| MLM | MARTIN MARIETTA MATLS INC | 0.29% | 26,000 | $14,994,200 | 26,000 | New | $576.7 | 13F |
| FULC | FULCRUM THERAPEUTICS INC | 0.26% | 3,680,921 | $13,472,171 | -2,880,190 | -43.9% | $3.66 | 13F |
| PLNT | PLANET FITNESS MASTER ISSUER | 0.22% | 219,910 | $11,472,705 | 219,910 | New | $52.17 | 13F |
| BE | BLOOM ENERGY CORP | 0.20% | 33,800 | $10,231,260 | 33,800 | New | $302.7 | 13F |
| KARD | KARDIGAN INC | 0.18% | 400,000 | $9,540,000 | 400,000 | New | $23.85 | 13F |
| CVS | CVS HEALTH CORP | 0.17% | 84,500 | $8,741,525 | 84,500 | New | $103.45 | 13F |
| MOLN | MOLECULAR PARTNERS AG | 0.17% | 2,221,494 | $8,597,182 | | No Change | $3.87 | 13F |
| AVR | ANTERIS TECHNOLOGIES GLOBAL | 0.16% | 850,000 | $8,372,500 | | No Change | $9.85 | 13F |
| DXCM | DEXCOM INC | 0.13% | 101,980 | $6,868,353 | 70,300 | 221.91% | $67.35 | 13F |
| TMO | THERMO FISHER SCIENTIFIC INC | 0.13% | 13,400 | $6,718,224 | | No Change | $501.36 | 13F |
| ABT | ABBOTT LABORATORIES | 0.12% | 66,920 | $6,072,321 | | No Change | $90.74 | 13F |
| BSX | BOSTON SCIENTIFIC CORP | 0.12% | 140,083 | $5,978,742 | 16,142 | 13.02% | $42.68 | 13F |
| CNC | CENTENE CORP DEL | 0.12% | 99,100 | $6,361,229 | 99,100 | New | $64.19 | 13F |
| DHR | DANAHER CORP DEL | 0.10% | 26,600 | $5,066,768 | -9,780 | -26.88% | $190.48 | 13F |
| ISRG | INTUITIVE SURGICAL INC | 0.10% | 13,600 | $5,408,448 | 2,300 | 20.35% | $397.68 | 13F |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 0.09% | 121,297 | $4,513,461 | 121,297 | New | $37.21 | 13F |
| MLYS | MINERALYS THERAPEUTICS INC | 0.09% | 173,886 | $4,691,444 | -1,364,776 | -88.7% | $26.98 | 13F |
| COR | CENCORA INC | 0.07% | 12,488 | $3,533,854 | | No Change | $282.98 | 13F |
| MSLE | SATELLOS BIOSCIENCE INC | 0.07% | 475,000 | $3,693,125 | | No Change | $7.78 | 13F |
| TRLV | TRULIEVE CANNABIS CORP | 0.07% | 356,100 | $3,500,463 | 356,100 | New | $9.83 | 13F |
| ABEO | ABEONA THERAPEUTICS INC | 0.06% | 500,000 | $3,090,000 | -2,176,000 | -81.32% | $6.18 | 13F |
| NTRA | NATERA INC | 0.05% | 10,100 | $2,741,645 | | No Change | $271.45 | 13F |
| JNJ | JOHNSON & JOHNSON | 0.04% | 7,700 | $1,955,569 | -15,700 | -67.09% | $253.97 | 13F |
| LRCX | LAM RESEARCH CORP | 0.04% | 4,302 | $1,864,186 | 4,302 | New | $433.33 | 13F |
| MSFT | MICROSOFT CORP | 0.04% | 4,970 | $1,853,909 | | No Change | $373.02 | 13F |
| SYK | STRYKER CORPORATION | 0.04% | 5,860 | $1,844,962 | | No Change | $314.84 | 13F |
| IQV | IQVIA HLDGS INC | 0.03% | 7,175 | $1,386,354 | | No Change | $193.22 | 13F |
| PFGC | PERFORMANCE FOOD GROUP CO | 0.03% | 14,710 | $1,644,431 | -372,175 | -96.2% | $111.79 | 13F |
| SNOW | SNOWFLAKE INC | 0.03% | 5,600 | $1,425,200 | 5,600 | New | $254.5 | 13F |
| EW | EDWARDS LIFESCIENCES CORP | 0.03% | 18,700 | $1,691,602 | | No Change | $90.46 | 13F |
| MCK | MCKESSON CORP | 0.03% | 1,830 | $1,382,748 | | No Change | $755.6 | 13F |
| MDLN | MEDLINE INC | 0.03% | 42,500 | $1,676,200 | | No Change | $39.44 | 13F |
| GOOG | ALPHABET INC | 0.02% | 3,400 | $1,201,322 | 3,400 | New | $353.33 | 13F |
| GWW | WW GRAINGER INC | 0.02% | 770 | $1,047,508 | -230 | -23% | $1360.4 | 13F |
| HCA | HCA HEALTHCARE INC | 0.02% | 3,190 | $1,243,749 | | No Change | $389.89 | 13F |
| IONS | IONIS PHARMACEUTICALS INC | 0.02% | 10,800 | $856,332 | | No Change | $79.29 | 13F |
| WAT | WATERS CORP | 0.02% | 3,225 | $1,209,504 | | No Change | $375.04 | 13F |
| A | AGILENT TECHNOLOGIES INC | 0.01% | 4,990 | $662,822 | | No Change | $132.83 | 13F |
| USFD | US FOODS HLDG CORP | 0.01% | 6,920 | $707,570 | -389,050 | -98.25% | $102.25 | 13F |
| VLTO | VERALTO CORP | 0.00941% | 5,475 | $485,523 | | No Change | $88.68 | 13F |
| RMD | RESMED INC | 0.00902% | 2,390 | $465,763 | | No Change | $194.88 | 13F |
| STE | STERIS PLC | 0.00624% | 1,530 | $322,172 | | No Change | $210.57 | 13F |
| SRPT | SAREPTA THERAPEUTICS INC | 0.00623% | 17,888 | $321,447 | | No Change | $17.97 | 13F |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 0.00544% | 3,260 | $280,653 | | No Change | $86.09 | 13F |
| CRL | CHARLES RIV LABS INTL INC | 0.00444% | 1,010 | $229,058 | 1,010 | New | $226.79 | 13F |
| INM | INMED PHARMACEUTICALS INC | 0.00300% | 100,000 | $155,000 | 100,000 | New | $1.55 | 13F |
| APLS | APELLIS PHARMACEUTICALS INC | | | | -3,518,471 | Exited | | 13F |
| COHR | COHERENT CORP | | | | -30,000 | Exited | | 13F |
| ERAS | ERASCA INC | | | | -3,434,967 | Exited | | 13F |
| KALV | KALVISTA PHARMACEUTICALS INC | | | | -4,768,712 | Exited | | 13F |
| KZR | KEZAR LIFE SCIENCES INC | | | | -716,759 | Exited | | 13F |
| LTH | LIFE TIME GROUP HOLDINGS INC | | | | -510,349 | Exited | | 13F |
| MTD | METTLER TOLEDO INTERNATIONAL | | | | -1,964 | Exited | | 13F |
| RBLX | ROBLOX CORP | | | | -8,420 | Exited | | 13F |
| TLN | TALEN ENERGY CORP | | | | -5,970 | Exited | | 13F |
| TSLA | TESLA INC | | | | -5,177 | Exited | | 13F |
| VRDN | VIRIDIAN THERAPEUTICS INC | | | | -16,700 | Exited | | 13F |
| VST | VISTRA CORP | | | | -6,000 | Exited | | 13F |
| WING | WINGSTOP INC | | | | -59,500 | Exited | | 13F |
| MDT | MEDTRONIC PLC | | | | -72,260 | Exited | | 13F |
