Regulus Therapeutics Inc. (RGLS) NASDAQ
$2.22 (0.04) (-1.77%)
Market Cap: $147.95M
As of 04/24/24 04:00 PM EDT. Market closed.
Regulus Therapeutics Inc. (RGLS)
NASDAQ
$2.22
(0.04) (-1.77%)
Market Cap: $147.95M
As of 04/24/24 04:00 PM EDT. Market closed.
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regulus therapeutics inc. (nasdaq:rgls) is a biopharmaceutical company leading the discovery and development of innovative medicines targeting micrornas. regulus has leveraged its oligonucleotide drug discovery and development expertise to develop a well-balanced microrna therapeutics pipeline complemented by a maturing micromarkerssm biomarkers platform and a rich intellectual property estate to ... read more
COMPANY PROFILE
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
Joseph Hagan
Full Time Employees
47
CEO Compensation (Base)
$475,300
CEO Compensation (Total)
$1.92M
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
Joseph Hagan
Full Time Employees
47
CEO Compensation (Base)
$475,300
CEO Compensation (Total)
$1.92M
Address
10628 Science Center Dr Ste 225, California, San Diego, 92121-1124.
PRICE CHART FOR REGULUS THERAPEUTICS INC
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NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
$2.24
Previous Close
$2.26
Days Range
$2.22 - $2.29
52 week range
$1.08 - $3.79
Volume
91,807
Avg. Volume (30 days)
417,082
Market Cap
$147.95M
Dividend Yield
-
P/E
-
Shares Outstanding
65,465,251
Open
$2.24
Previous Close
$2.26
Days Range
$2.22 - $2.29
52 week range
$1.08 - $3.79
Volume
91,807
Avg. Volume (30 days)
417,082
Market Cap
$147.95M
Dividend Yield
-
P/E
-
Shares Outstanding
65,465,251
FINANCIAL STATEMENTS FOR REGULUS THERAPEUTICS INC
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INSIDER TRANSACTIONS FOR REGULUS THERAPEUTICS INC
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| PAPADOPOULOS STELIOS | Director | Mar 14, 2024 | Option Exercise | $1.60 | 250,000 | 400,000 | 978,388 | Mar 15, 2024, 04:19 PM |
| CALSADA CRISPINA | Chief Financial Officer | Jan 18, 2024 | Sale | $1.19 | 5,468 | 6,510 | 5,782 | Jan 18, 2024, 08:24 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Jan 18, 2024 | Sale | $1.19 | 5,468 | 6,510 | 10,056 | Jan 18, 2024, 08:23 PM |
| Hagan Joseph P | Chief Executive Officer | Jan 18, 2024 | Sale | $1.19 | 14,580 | 17,359 | 57,112 | Jan 18, 2024, 08:22 PM |
| PAPADOPOULOS STELIOS | Director | Apr 13, 2023 | Option Exercise | $0.90 | 222,198 | 200,000 | 728,388 | Apr 14, 2023, 04:39 PM |
| Drygin Denis | Chief Scientific Officer | Mar 01, 2022 | Buy | $0.23 | 76,686 | 17,638 | 100,000 | Mar 01, 2022, 05:58 PM |
| Drygin Denis | Chief Scientific Officer | Feb 04, 2022 | Buy | $0.23 | 23,314 | 5,362 | 23,314 | Feb 07, 2022, 05:09 PM |
| Hagan Joseph P | President and CEO | Jan 26, 2022 | Buy | $0.22 | 100,000 | 21,520 | 417,006 | Jan 26, 2022, 04:13 PM |
| PAPADOPOULOS STELIOS | Director | Nov 30, 2021 | Option Exercise | $0.36 | 2,222,222 | 800,000 | 5,061,929 | Dec 01, 2021, 04:12 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | May 17, 2021 | Sale | $0.89 | 860 | 765 | 41,754 | May 17, 2021, 07:12 PM |
| Hagan Joseph P | President and CEO | Feb 16, 2021 | Sale | $1.72 | 4,144 | 7,128 | 244,628 | Apr 16, 2021, 04:11 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Feb 16, 2021 | Sale | $1.72 | 828 | 1,424 | 42,614 | Feb 17, 2021, 05:23 PM |
| Hagan Joseph P | President and CEO | Feb 16, 2021 | Sale | $1.72 | 4,144 | 7,128 | 485,756 | Feb 17, 2021, 05:23 PM |
| PAPADOPOULOS STELIOS | Director | Dec 04, 2020 | Option Exercise | $0.63 | 793,528 | 500,002 | 2,839,707 | Jan 27, 2021, 08:16 PM |
| Walker Paul Edward | 10% Owner | Dec 04, 2020 | Buy | $0.62 | 4,398,602 | 2,735,930 | 6,451,056 | Dec 07, 2020, 05:14 PM |
| Sonsini Peter W. | 10% Owner | Dec 04, 2020 | Buy | $0.62 | 4,398,602 | 2,735,930 | 6,451,056 | Dec 07, 2020, 05:13 PM |
| SANDELL SCOTT D | 10% Owner | Dec 04, 2020 | Buy | $0.62 | 4,398,602 | 2,735,930 | 6,451,056 | Dec 07, 2020, 05:12 PM |
| MAKOWER JOSHUA | 10% Owner | Dec 04, 2020 | Buy | $0.62 | 4,398,602 | 2,735,930 | 6,451,056 | Dec 07, 2020, 05:12 PM |
| Makhzoumi Mohamad | 10% Owner | Dec 04, 2020 | Buy | $0.62 | 4,398,602 | 2,735,930 | 6,451,056 | Dec 07, 2020, 05:11 PM |
| Florence Anthony A. Jr. | 10% Owner | Dec 04, 2020 | Buy | $0.62 | 4,398,602 | 2,735,930 | 6,451,056 | Dec 07, 2020, 05:10 PM |
| Chang Carmen | 10% Owner | Dec 04, 2020 | Buy | $0.62 | 4,398,602 | 2,735,930 | 6,451,056 | Dec 07, 2020, 05:10 PM |
| Behbahani Ali | 10% Owner | Dec 04, 2020 | Buy | $0.62 | 4,398,602 | 2,735,930 | 6,451,056 | Dec 07, 2020, 05:09 PM |
| BASKETT FOREST | 10% Owner | Dec 04, 2020 | Buy | $0.62 | 4,398,602 | 2,735,930 | 6,451,056 | Dec 07, 2020, 05:08 PM |
| Growth Equity Opportunities V, LLC | 10% Owner | Dec 04, 2020 | Buy | $0.62 | 4,398,602 | 2,735,930 | 6,451,056 | Dec 07, 2020, 05:06 PM |
| Hagan Joseph P | President and CEO | Dec 04, 2020 | Option Exercise | $0.63 | 39,680 | 25,002 | 225,674 | Dec 07, 2020, 04:22 PM |
| PAPADOPOULOS STELIOS | Director | Dec 04, 2020 | Option Exercise | $0.63 | 793,528 | 500,002 | 1,986,729 | Dec 07, 2020, 04:21 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Nov 16, 2020 | Sale | $0.52 | 876 | 456 | 25,762 | Nov 18, 2020, 04:10 PM |
| Hagan Joseph P | President and CEO | Nov 16, 2020 | Sale | $0.52 | 6,094 | 3,176 | 215,994 | Nov 18, 2020, 04:09 PM |
| Hagan Joseph P | President and CEO | Aug 14, 2020 | Sale | $0.60 | 4,245 | 2,568 | 222,088 | Aug 17, 2020, 08:22 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Aug 14, 2020 | Sale | $0.61 | 872 | 528 | 26,638 | Aug 17, 2020, 08:21 PM |
| Hagan Joseph P | President and CEO | May 15, 2020 | Sale | $0.63 | 4,426 | 2,774 | 226,333 | May 18, 2020, 04:28 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | May 15, 2020 | Sale | $0.63 | 909 | 570 | 27,510 | May 18, 2020, 04:27 PM |
| Hagan Joseph P | President and CEO | Feb 18, 2020 | Sale | $0.83 | 4,324 | 3,591 | 230,759 | Feb 19, 2020, 06:09 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Feb 18, 2020 | Sale | $0.83 | 888 | 737 | 28,419 | Feb 19, 2020, 06:08 PM |
| Hagan Joseph P | President and CEO | Jan 02, 2020 | Sale | $0.97 | 8,345 | 8,067 | 235,083 | Jan 03, 2020, 04:07 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Jan 02, 2020 | Sale | $0.97 | 2,239 | 2,164 | 29,307 | Jan 03, 2020, 04:06 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Nov 14, 2019 | Sale | $0.64 | 833 | 533 | 31,546 | Nov 15, 2019, 05:37 PM |
| Hagan Joseph P | President and CEO | Nov 14, 2019 | Sale | $0.64 | 5,838 | 3,736 | 243,428 | Nov 15, 2019, 05:36 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Oct 01, 2019 | Sale | $0.68 | 2,346 | 1,602 | 32,379 | Oct 02, 2019, 06:50 PM |
| Hagan Joseph P | President and CEO | Oct 01, 2019 | Sale | $0.68 | 8,743 | 5,969 | 249,266 | Oct 02, 2019, 06:17 PM |
| Hagan Joseph P | President and CEO | Aug 15, 2019 | Sale | $0.55 | 4,375 | 2,409 | 258,009 | Aug 16, 2019, 04:17 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Aug 15, 2019 | Sale | $0.55 | 899 | 495 | 34,725 | Aug 16, 2019, 04:16 PM |
| Hagan Joseph P | President and CEO | Jul 01, 2019 | Sale | $1.31 | 5,783 | 7,584 | 262,384 | Jul 02, 2019, 05:42 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Jul 01, 2019 | Sale | $1.31 | 2,225 | 2,918 | 35,624 | Jul 02, 2019, 05:42 PM |
| Chevallard Daniel R. | Chief Financial Officer | Jul 01, 2019 | Sale | $1.31 | 2,669 | 3,500 | 77,870 | Jul 02, 2019, 05:41 PM |
| PAPADOPOULOS STELIOS | Director | May 07, 2019 | Option Exercise | $1.08 | 370,370 | 400,000 | 1,189,872 | May 21, 2019, 04:46 PM |
| RASTETTER WILLIAM H | Director | May 07, 2019 | Option Exercise | $1.08 | 92,889 | 100,320 | 154,223 | May 21, 2019, 04:45 PM |
| Witz Pascale | Director | May 07, 2019 | Option Exercise | $1.08 | 29,630 | 32,000 | 37,849 | May 21, 2019, 04:44 PM |
| Hagan Joseph P | President and CEO | May 07, 2019 | Option Exercise | $1.08 | 33,194 | 35,850 | 64,542 | May 21, 2019, 04:42 PM |
| Hagan Joseph P | President and CEO | May 16, 2019 | Sale | $1.22 | 39,352 | 47,966 | 268,167 | May 16, 2019, 05:25 PM |
| Chevallard Daniel R. | Chief Financial Officer | May 15, 2019 | Sale | $1.41 | 10,000 | 14,089 | 80,539 | May 16, 2019, 05:21 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | May 15, 2019 | Sale | $1.41 | 6,950 | 9,796 | 59,309 | May 16, 2019, 05:21 PM |
| Walker Paul Edward | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 10, 2019, 10:59 AM |
| Walker Paul Edward | Director | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:08 PM |
| Sonsini Peter W. | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:07 PM |
| SANDELL SCOTT D | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:07 PM |
| MOTT DAVID M | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:06 PM |
| MAKOWER JOSHUA | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:06 PM |
| Makhzoumi Mohamad | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:05 PM |
| Florence Anthony A. Jr. | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:05 PM |
| Chang Carmen | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:05 PM |
| Behbahani Ali | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:04 PM |
| BASKETT FOREST | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:04 PM |
| BARRIS PETER J | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:02 PM |
| Growth Equity Opportunities V, LLC | 10% Owner | May 07, 2019 | Buy | $1.08 | 1,136,704 | 1,227,640 | 2,052,454 | May 09, 2019, 06:02 PM |
| Hagan Joseph P | President and CEO | May 07, 2019 | Buy | $1.08 | 33,194 | 35,850 | 64,542 | May 08, 2019, 05:15 PM |
| Witz Pascale | Director | May 07, 2019 | Buy | $1.08 | 29,630 | 32,000 | 37,849 | May 08, 2019, 05:15 PM |
| RASTETTER WILLIAM H | Director | May 07, 2019 | Buy | $1.08 | 92,889 | 100,320 | 154,223 | May 08, 2019, 05:14 PM |
| PAPADOPOULOS STELIOS | Director | May 07, 2019 | Buy | $1.08 | 370,370 | 400,000 | 1,189,872 | May 08, 2019, 05:13 PM |
| Hagan Joseph P | President and CEO | Apr 01, 2019 | Sale | $0.98 | 5,842 | 5,731 | 31,348 | Apr 03, 2019, 04:31 PM |
| Aker Christopher Ray | Sr. VP & General Counsel | Apr 01, 2019 | Sale | $0.98 | 2,710 | 2,659 | 6,287 | Apr 03, 2019, 04:15 PM |
| Chevallard Daniel R. | Chief Financial Officer | Apr 01, 2019 | Sale | $0.98 | 3,253 | 3,192 | 9,372 | Apr 03, 2019, 12:00 AM |
| WRIGHT TIMOTHY MICHAEL | Chief R & D Officer | Feb 05, 2019 | Option Exercise | $0.95 | 40,000 | 38,000 | 62,893 | Feb 06, 2019, 04:52 PM |
| Hagan Joseph P | President and CEO | Feb 05, 2019 | Option Exercise | $0.95 | 65,000 | 61,750 | 84,148 | Feb 06, 2019, 04:51 PM |
| Chevallard Daniel R. | Chief Financial Officer | Feb 05, 2019 | Option Exercise | $0.95 | 30,000 | 28,500 | 34,578 | Feb 06, 2019, 04:50 PM |
| PAPADOPOULOS STELIOS | Director | Dec 28, 2018 | Buy | $1.09 | 50,000 | 54,570 | 835,073 | Jan 02, 2019, 04:12 PM |
| PAPADOPOULOS STELIOS | Director | Dec 26, 2018 | Buy | $0.95 | 90,000 | 85,878 | 758,672 | Dec 28, 2018, 04:21 PM |
| PAPADOPOULOS STELIOS | Director | Dec 27, 2018 | Buy | $1.04 | 26,401 | 27,460 | 785,073 | Dec 28, 2018, 04:21 PM |
| PAPADOPOULOS STELIOS | Director | Nov 16, 2018 | Buy | $1.38 | 300,000 | 415,470 | 668,672 | Nov 19, 2018, 04:03 PM |
| PAPADOPOULOS STELIOS | Director | Nov 15, 2018 | Buy | $1.33 | 200,000 | 265,080 | 368,672 | Nov 19, 2018, 04:03 PM |
| Collier Kathryn J | Director | Nov 16, 2018 | Buy | $1.41 | 7,100 | 10,011 | 27,596 | Nov 19, 2018, 04:01 PM |
| Collier Kathryn J | Director | Jun 05, 2018 | Option Exercise | $0.74 | 7,695 | 5,694 | 7,695 | Jun 05, 2018, 04:28 PM |
| Collier Kathryn J | Director | Apr 14, 2018 | Option Exercise | $0.64 | 60,234 | 38,550 | 60,234 | Apr 17, 2018, 04:36 PM |
| BALTIMORE DAVID | Director | Dec 04, 2017 | Option Exercise | $0.89 | 60,674 | 54,000 | 60,674 | Dec 06, 2017, 07:43 PM |
| FOLETTA MARK G | Director | Dec 04, 2017 | Option Exercise | $0.89 | 71,910 | 64,000 | 81,910 | Dec 06, 2017, 07:42 PM |
| PAPADOPOULOS STELIOS | Director | Dec 04, 2017 | Option Exercise | $0.89 | 96,629 | 86,000 | 1,797,306 | Dec 06, 2017, 07:41 PM |
| Rosen Hugh | Director | Dec 04, 2017 | Option Exercise | $0.89 | 56,179 | 49,999 | 56,179 | Dec 06, 2017, 07:40 PM |
| Witz Pascale | Director | Dec 04, 2017 | Option Exercise | $0.89 | 60,674 | 54,000 | 60,674 | Dec 06, 2017, 07:39 PM |
| RASTETTER WILLIAM H | Director | Dec 04, 2017 | Option Exercise | $0.89 | 69,662 | 61,999 | 694,387 | Dec 06, 2017, 07:38 PM |
| WRIGHT TIMOTHY MICHAEL | Chief R & D Officer | Jul 25, 2017 | Buy | $0.91 | 274,725 | 250,000 | 274,725 | Jul 25, 2017, 06:09 PM |
| RASTETTER WILLIAM H | Director | Jul 25, 2017 | Buy | $0.91 | 274,725 | 250,000 | 624,625 | Jul 25, 2017, 06:09 PM |
| Hagan Joseph P | President and CEO | Jul 25, 2017 | Buy | $0.91 | 219,780 | 200,000 | 241,297 | Jul 25, 2017, 06:08 PM |
| Chevallard Daniel R. | Chief Financial Officer | Jul 25, 2017 | Buy | $0.91 | 54,945 | 50,000 | 59,415 | Jul 25, 2017, 06:07 PM |
| PAPADOPOULOS STELIOS | Director | Jul 25, 2017 | Buy | $0.91 | 1,000,000 | 910,000 | 1,770,677 | Jul 25, 2017, 06:06 PM |
| PAPADOPOULOS STELIOS | Director | Mar 22, 2017 | Buy | $1.23 | 300,000 | 368,100 | 700,677 | Mar 23, 2017, 04:26 PM |
| PAPADOPOULOS STELIOS | Director | Mar 21, 2017 | Buy | $1.20 | 200,000 | 239,800 | 400,677 | Mar 23, 2017, 04:26 PM |
| RASTETTER WILLIAM H | Director | Mar 07, 2017 | Buy | $1.15 | 250,000 | 287,500 | 350,000 | Mar 07, 2017, 04:59 PM |
| Hagan Joseph P | Chief Operating Officer | Mar 03, 2016 | Buy | $7.19 | 10,000 | 71,900 | 10,000 | Mar 07, 2016, 05:20 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Feb 23, 2016 | Sale | $7.18 | 1,000,000 | 7,180,000 | 4,896,716 | Feb 24, 2016, 06:20 PM |
| FOLETTA MARK G | Director | Aug 13, 2015 | Buy | $7.64 | 10,000 | 76,405 | 10,000 | Aug 13, 2015, 06:10 PM |
| PAPADOPOULOS STELIOS | Director | Aug 07, 2015 | Option Exercise | $1.55 | 50,677 | 78,801 | 200,677 | Aug 07, 2015, 06:05 PM |
| RASTETTER WILLIAM H | Director | Jul 21, 2015 | Buy | $10.19 | 61,235 | 624,199 | 100,000 | Jul 21, 2015, 08:47 PM |
| RASTETTER WILLIAM H | Director | Jul 20, 2015 | Buy | $10.13 | 38,765 | 392,779 | 38,765 | Jul 21, 2015, 08:47 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Jul 16, 2015 | Sale | $10.79 | 167,000 | 1,801,362 | 5,284,172 | Jul 17, 2015, 06:08 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Jul 15, 2015 | Sale | $10.76 | 65,133 | 700,961 | 5,451,172 | Jul 17, 2015, 06:08 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Jul 17, 2015 | Sale | $10.21 | 111,000 | 1,133,754 | 5,173,172 | Jul 17, 2015, 06:08 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Jun 30, 2015 | Sale | $10.79 | 13,248 | 143,010 | 5,516,305 | Jul 02, 2015, 04:28 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Apr 21, 2015 | Option Exercise | $0.38 | 60,000 | 22,800 | 63,705 | Apr 21, 2015, 07:06 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Apr 20, 2015 | Option Exercise | $0.38 | 66,071 | 25,107 | 69,776 | Apr 21, 2015, 07:06 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Apr 17, 2015 | Option Exercise | $0.38 | 73,929 | 28,093 | 77,634 | Apr 21, 2015, 07:06 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Apr 21, 2015 | Sale | $17.73 | 60,000 | 1,063,980 | 3,705 | Apr 21, 2015, 07:06 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Apr 20, 2015 | Sale | $16.85 | 66,071 | 1,113,514 | 3,705 | Apr 21, 2015, 07:06 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Apr 17, 2015 | Sale | $16.94 | 73,929 | 1,252,002 | 3,705 | Apr 21, 2015, 07:06 PM |
| CARTER BRUCE L A | Director | Apr 13, 2015 | Option Exercise | $4.78 | 20,000 | 95,600 | 20,000 | Apr 14, 2015, 05:12 PM |
| CARTER BRUCE L A | Director | Apr 13, 2015 | Sale | $17.66 | 20,000 | 353,164 | 0 | Apr 14, 2015, 05:12 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Mar 05, 2015 | Option Exercise | $0.38 | 89,230 | 33,907 | 91,696 | Mar 05, 2015, 07:17 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Mar 05, 2015 | Sale | $20.26 | 89,230 | 1,808,063 | 26,082 | Mar 05, 2015, 07:17 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Feb 27, 2015 | Option Exercise | $0.38 | 70 | 27 | 2,536 | Mar 03, 2015, 05:27 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Feb 27, 2015 | Sale | $19.50 | 70 | 1,365 | 2,466 | Mar 03, 2015, 05:27 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Feb 02, 2015 | Option Exercise | $0.38 | 2,400 | 912 | 4,866 | Feb 03, 2015, 05:39 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Jan 30, 2015 | Option Exercise | $0.38 | 3,300 | 1,254 | 5,766 | Feb 03, 2015, 05:39 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Feb 02, 2015 | Sale | $19.77 | 2,400 | 47,440 | 2,466 | Feb 03, 2015, 05:39 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Jan 30, 2015 | Sale | $19.50 | 3,300 | 64,351 | 2,466 | Feb 03, 2015, 05:39 PM |
| Gibson Neil W | Chief Scientific Officer | Jan 28, 2015 | Sale | $18.05 | 80,000 | 1,444,304 | 8,655 | Jan 30, 2015, 05:45 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Jan 28, 2015 | Option Exercise | $0.38 | 85,000 | 32,300 | 87,466 | Jan 30, 2015, 05:22 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Jan 29, 2015 | Option Exercise | $0.38 | 60,000 | 22,800 | 62,466 | Jan 30, 2015, 05:22 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Jan 28, 2015 | Sale | $18.08 | 85,000 | 1,536,515 | 15,455 | Jan 30, 2015, 05:22 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Jan 29, 2015 | Sale | $18.04 | 60,000 | 1,082,634 | 28,693 | Jan 30, 2015, 05:22 PM |
| PAPADOPOULOS STELIOS | Director | Dec 12, 2014 | Option Exercise | $0.38 | 150,000 | 57,000 | 150,000 | Dec 15, 2014, 12:58 PM |
| Gibson Neil W | Chief Scientific Officer | Nov 28, 2014 | Option Exercise | $1.74 | 2,500 | 4,350 | 82,500 | Dec 01, 2014, 04:49 PM |
| Gibson Neil W | Chief Scientific Officer | Nov 28, 2014 | Sale | $19.30 | 2,500 | 48,245 | 81,500 | Dec 01, 2014, 04:49 PM |
| ASTRAZENECA PLC | 10% Owner | Nov 12, 2014 | Sale | $17.00 | 2,000,000 | 34,000,000 | 4,250,000 | Nov 14, 2014, 04:05 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Nov 03, 2014 | Sale | $15.94 | 1,279,411 | 20,390,613 | 5,516,305 | Nov 05, 2014, 06:48 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Oct 29, 2014 | Option Exercise | $0.38 | 3,505 | 1,332 | 5,971 | Oct 31, 2014, 04:52 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Oct 29, 2014 | Sale | $19.35 | 3,505 | 67,824 | 4,571 | Oct 31, 2014, 04:52 PM |
| Gibson Neil W | Chief Scientific Officer | Oct 29, 2014 | Option Exercise | $1.74 | 2,500 | 4,350 | 82,500 | Oct 31, 2014, 04:50 PM |
| Gibson Neil W | Chief Scientific Officer | Oct 29, 2014 | Sale | $19.29 | 2,500 | 48,234 | 81,400 | Oct 31, 2014, 04:50 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 22, 2014 | Sale | $14.00 | 109,534 | 1,533,135 | 6,899,517 | Oct 28, 2014, 05:03 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 24, 2014 | Sale | $15.19 | 1,850 | 28,109 | 6,796,512 | Oct 28, 2014, 05:03 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 23, 2014 | Sale | $14.24 | 1,700 | 24,202 | 6,798,066 | Oct 28, 2014, 05:03 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 24, 2014 | Sale | $15.19 | 1,850 | 28,109 | 5,897,512 | Oct 28, 2014, 04:59 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 23, 2014 | Sale | $14.24 | 1,700 | 24,202 | 5,899,066 | Oct 28, 2014, 04:59 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 22, 2014 | Sale | $14.00 | 109,534 | 1,533,135 | 6,000,517 | Oct 28, 2014, 04:59 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 24, 2014 | Sale | $15.19 | 1,850 | 28,109 | 6,795,716 | Oct 24, 2014, 09:29 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 23, 2014 | Sale | $14.24 | 1,700 | 24,202 | 6,797,566 | Oct 24, 2014, 09:29 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 22, 2014 | Sale | $14.00 | 109,534 | 1,533,126 | 6,799,266 | Oct 24, 2014, 09:29 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 24, 2014 | Sale | $15.19 | 1,850 | 28,109 | 5,896,716 | Oct 24, 2014, 09:27 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 23, 2014 | Sale | $14.24 | 1,700 | 24,202 | 5,898,566 | Oct 24, 2014, 09:27 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 22, 2014 | Sale | $14.00 | 109,534 | 1,533,126 | 5,900,266 | Oct 24, 2014, 09:27 PM |
| Gibson Neil W | Chief Scientific Officer | Oct 22, 2014 | Option Exercise | $1.74 | 3,300 | 5,742 | 83,300 | Oct 24, 2014, 04:16 PM |
| Gibson Neil W | Chief Scientific Officer | Oct 22, 2014 | Sale | $14.44 | 3,300 | 47,644 | 80,000 | Oct 24, 2014, 04:16 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Oct 20, 2014 | Option Exercise | $0.38 | 300 | 114 | 2,766 | Oct 21, 2014, 04:07 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Oct 17, 2014 | Option Exercise | $0.38 | 400 | 152 | 2,866 | Oct 21, 2014, 04:07 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Oct 17, 2014 | Sale | $7.04 | 400 | 2,816 | 2,466 | Oct 21, 2014, 04:07 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Oct 20, 2014 | Sale | $7.00 | 300 | 2,100 | 2,466 | Oct 21, 2014, 04:07 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 17, 2014 | Sale | $6.79 | 3,000 | 20,371 | 6,908,800 | Oct 17, 2014, 05:38 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 16, 2014 | Sale | $6.76 | 4,800 | 32,450 | 6,911,800 | Oct 17, 2014, 05:38 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 15, 2014 | Sale | $6.67 | 4,300 | 28,687 | 6,916,600 | Oct 17, 2014, 05:38 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 17, 2014 | Sale | $6.79 | 3,000 | 20,371 | 6,009,800 | Oct 17, 2014, 05:37 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 16, 2014 | Sale | $6.76 | 4,800 | 32,450 | 6,012,800 | Oct 17, 2014, 05:37 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 15, 2014 | Sale | $6.67 | 4,300 | 28,687 | 6,017,600 | Oct 17, 2014, 05:37 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Oct 14, 2014 | Option Exercise | $0.38 | 400 | 152 | 2,866 | Oct 14, 2014, 05:54 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Oct 09, 2014 | Option Exercise | $0.38 | 105 | 40 | 2,571 | Oct 14, 2014, 05:54 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Oct 09, 2014 | Sale | $7.00 | 105 | 735 | 2,466 | Oct 14, 2014, 05:54 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Oct 14, 2014 | Sale | $7.00 | 400 | 2,800 | 2,466 | Oct 14, 2014, 05:54 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 10, 2014 | Sale | $6.41 | 2,000 | 12,813 | 6,920,900 | Oct 10, 2014, 06:26 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 09, 2014 | Sale | $6.58 | 4,750 | 31,238 | 6,922,900 | Oct 10, 2014, 06:26 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 08, 2014 | Sale | $6.63 | 3,300 | 21,888 | 6,927,650 | Oct 10, 2014, 06:26 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 10, 2014 | Sale | $6.41 | 2,000 | 12,813 | 6,021,900 | Oct 10, 2014, 06:25 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 09, 2014 | Sale | $6.58 | 4,750 | 31,238 | 6,023,900 | Oct 10, 2014, 06:25 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 08, 2014 | Sale | $6.63 | 3,300 | 21,888 | 6,028,650 | Oct 10, 2014, 06:25 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 03, 2014 | Sale | $6.88 | 3,300 | 22,688 | 6,930,950 | Oct 03, 2014, 05:20 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 02, 2014 | Sale | $6.64 | 3,750 | 24,903 | 6,934,250 | Oct 03, 2014, 05:20 PM |
| ISIS PHARMACEUTICALS INC | Director | Oct 01, 2014 | Sale | $6.71 | 3,250 | 21,808 | 6,938,000 | Oct 03, 2014, 05:20 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 03, 2014 | Sale | $6.88 | 3,300 | 22,688 | 6,031,950 | Oct 03, 2014, 05:19 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 02, 2014 | Sale | $6.64 | 3,750 | 24,903 | 6,035,250 | Oct 03, 2014, 05:19 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Oct 01, 2014 | Sale | $6.71 | 3,250 | 21,808 | 6,039,000 | Oct 03, 2014, 05:19 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Sep 30, 2014 | Option Exercise | $0.38 | 2,300 | 874 | 4,766 | Oct 02, 2014, 07:17 PM |
| XANTHOPOULOS KLEANTHIS G | President and CEO | Sep 30, 2014 | Sale | $7.02 | 2,300 | 16,137 | 2,466 | Oct 02, 2014, 07:17 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 26, 2014 | Sale | $7.04 | 2,500 | 17,598 | 6,042,250 | Sep 26, 2014, 05:37 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 25, 2014 | Sale | $7.12 | 2,500 | 17,790 | 6,044,750 | Sep 26, 2014, 05:37 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 24, 2014 | Sale | $7.19 | 3,750 | 26,978 | 6,047,250 | Sep 26, 2014, 05:37 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 25, 2014 | Sale | $7.12 | 2,500 | 17,790 | 6,943,750 | Sep 26, 2014, 05:36 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 24, 2014 | Sale | $7.19 | 3,750 | 26,978 | 6,946,250 | Sep 26, 2014, 05:36 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 26, 2014 | Sale | $7.04 | 2,500 | 17,598 | 6,941,250 | Sep 26, 2014, 05:36 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 19, 2014 | Sale | $7.22 | 4,100 | 29,587 | 6,950,000 | Sep 19, 2014, 05:10 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 18, 2014 | Sale | $7.40 | 1,500 | 11,098 | 6,954,100 | Sep 19, 2014, 05:10 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 17, 2014 | Sale | $7.43 | 2,100 | 15,610 | 6,955,600 | Sep 19, 2014, 05:10 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 18, 2014 | Sale | $7.40 | 1,500 | 11,098 | 6,055,100 | Sep 19, 2014, 05:09 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 17, 2014 | Sale | $7.43 | 2,100 | 15,610 | 6,056,600 | Sep 19, 2014, 05:09 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 19, 2014 | Sale | $7.22 | 4,100 | 29,587 | 6,051,000 | Sep 19, 2014, 05:09 PM |
| Gibson Neil W | Chief Scientific Officer | Sep 12, 2014 | Option Exercise | $1.74 | 2,200 | 3,828 | 82,200 | Sep 15, 2014, 05:14 PM |
| Gibson Neil W | Chief Scientific Officer | Sep 11, 2014 | Option Exercise | $1.74 | 2,000 | 3,480 | 82,000 | Sep 15, 2014, 05:14 PM |
| Gibson Neil W | Chief Scientific Officer | Sep 12, 2014 | Sale | $8.01 | 2,200 | 17,616 | 80,000 | Sep 15, 2014, 05:14 PM |
| Gibson Neil W | Chief Scientific Officer | Sep 11, 2014 | Sale | $8.01 | 2,000 | 16,010 | 80,000 | Sep 15, 2014, 05:14 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 11, 2014 | Sale | $7.83 | 3,400 | 26,636 | 6,961,200 | Sep 12, 2014, 06:26 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 10, 2014 | Sale | $7.70 | 2,000 | 15,399 | 6,964,600 | Sep 12, 2014, 06:26 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 12, 2014 | Sale | $7.96 | 3,500 | 27,861 | 6,957,700 | Sep 12, 2014, 06:26 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 12, 2014 | Sale | $7.96 | 3,500 | 27,861 | 6,058,700 | Sep 12, 2014, 06:24 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 11, 2014 | Sale | $7.83 | 3,400 | 26,636 | 6,062,200 | Sep 12, 2014, 06:24 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 10, 2014 | Sale | $7.70 | 2,000 | 15,399 | 6,065,600 | Sep 12, 2014, 06:24 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 05, 2014 | Sale | $7.07 | 2,400 | 16,974 | 6,067,600 | Sep 05, 2014, 06:52 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 04, 2014 | Sale | $7.11 | 6,000 | 42,656 | 6,070,000 | Sep 05, 2014, 06:52 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Sep 03, 2014 | Sale | $6.95 | 1,650 | 11,471 | 6,076,000 | Sep 05, 2014, 06:52 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 03, 2014 | Sale | $6.95 | 1,650 | 11,471 | 6,975,000 | Sep 05, 2014, 05:57 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 05, 2014 | Sale | $7.07 | 2,400 | 16,974 | 6,966,600 | Sep 05, 2014, 05:57 PM |
| ISIS PHARMACEUTICALS INC | Director | Sep 04, 2014 | Sale | $7.11 | 6,000 | 42,656 | 6,969,000 | Sep 05, 2014, 05:57 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 29, 2014 | Sale | $6.84 | 1,500 | 10,254 | 6,976,650 | Aug 29, 2014, 07:13 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 28, 2014 | Sale | $6.96 | 2,000 | 13,921 | 6,978,150 | Aug 29, 2014, 07:13 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 27, 2014 | Sale | $7.21 | 1,500 | 10,821 | 6,980,150 | Aug 29, 2014, 07:13 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 29, 2014 | Sale | $6.84 | 1,500 | 10,254 | 6,077,650 | Aug 29, 2014, 07:12 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 28, 2014 | Sale | $6.96 | 2,000 | 13,921 | 6,079,150 | Aug 29, 2014, 07:12 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 27, 2014 | Sale | $7.21 | 1,500 | 10,821 | 6,081,150 | Aug 29, 2014, 07:12 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Aug 28, 2014 | Option Exercise | $0.38 | 3,505 | 1,332 | 3,505 | Aug 29, 2014, 05:19 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Aug 28, 2014 | Sale | $7.06 | 3,505 | 24,754 | 0 | Aug 29, 2014, 05:19 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 20, 2014 | Sale | $7.14 | 3,000 | 21,424 | 6,090,400 | Aug 22, 2014, 07:23 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 22, 2014 | Sale | $6.75 | 5,250 | 35,443 | 6,082,650 | Aug 22, 2014, 07:23 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 21, 2014 | Sale | $6.89 | 2,500 | 17,222 | 6,087,900 | Aug 22, 2014, 07:23 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 22, 2014 | Sale | $6.75 | 5,250 | 35,443 | 6,981,650 | Aug 22, 2014, 07:22 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 21, 2014 | Sale | $6.89 | 2,500 | 17,222 | 6,986,900 | Aug 22, 2014, 07:22 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 20, 2014 | Sale | $7.14 | 3,000 | 21,424 | 6,989,400 | Aug 22, 2014, 07:22 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 13, 2014 | Sale | $7.02 | 2,250 | 15,788 | 6,096,600 | Aug 15, 2014, 07:12 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 15, 2014 | Sale | $6.98 | 1,450 | 10,115 | 6,093,400 | Aug 15, 2014, 07:12 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 14, 2014 | Sale | $7.04 | 1,750 | 12,324 | 6,094,850 | Aug 15, 2014, 07:12 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 15, 2014 | Sale | $6.98 | 1,450 | 10,115 | 6,992,400 | Aug 15, 2014, 07:11 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 14, 2014 | Sale | $7.04 | 1,750 | 12,324 | 6,993,850 | Aug 15, 2014, 07:11 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 13, 2014 | Sale | $7.02 | 2,250 | 15,788 | 6,995,600 | Aug 15, 2014, 07:11 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 08, 2014 | Sale | $6.80 | 1,850 | 12,583 | 6,997,850 | Aug 08, 2014, 08:15 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 07, 2014 | Sale | $6.66 | 2,600 | 17,322 | 6,999,700 | Aug 08, 2014, 08:15 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 06, 2014 | Sale | $7.08 | 3,150 | 22,300 | 7,002,300 | Aug 08, 2014, 08:15 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 06, 2014 | Sale | $7.08 | 3,150 | 22,300 | 6,103,300 | Aug 08, 2014, 08:08 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 08, 2014 | Sale | $6.80 | 1,850 | 12,583 | 6,098,850 | Aug 08, 2014, 08:08 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 07, 2014 | Sale | $6.66 | 2,600 | 17,322 | 6,100,700 | Aug 08, 2014, 08:08 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Aug 05, 2014 | Option Exercise | $0.38 | 3,505 | 1,332 | 3,505 | Aug 07, 2014, 05:51 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Aug 05, 2014 | Sale | $7.06 | 3,505 | 24,739 | 0 | Aug 07, 2014, 05:51 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 31, 2014 | Sale | $6.42 | 1,750 | 11,235 | 6,109,050 | Aug 01, 2014, 06:52 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 30, 2014 | Sale | $6.60 | 1,000 | 6,602 | 6,110,800 | Aug 01, 2014, 06:52 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Aug 01, 2014 | Sale | $6.21 | 2,600 | 16,153 | 6,106,450 | Aug 01, 2014, 06:52 PM |
| ISIS PHARMACEUTICALS INC | Director | Aug 01, 2014 | Sale | $6.21 | 2,600 | 16,153 | 7,005,450 | Aug 01, 2014, 06:44 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 31, 2014 | Sale | $6.42 | 1,750 | 11,235 | 7,008,050 | Aug 01, 2014, 06:44 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 30, 2014 | Sale | $6.60 | 1,000 | 6,602 | 7,009,800 | Aug 01, 2014, 06:44 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 25, 2014 | Sale | $6.55 | 1,700 | 11,137 | 7,010,800 | Jul 25, 2014, 08:41 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 24, 2014 | Sale | $6.81 | 1,850 | 12,598 | 7,012,500 | Jul 25, 2014, 08:41 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 23, 2014 | Sale | $6.88 | 1,700 | 11,702 | 7,014,350 | Jul 25, 2014, 08:41 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 24, 2014 | Sale | $6.81 | 1,850 | 12,598 | 6,113,500 | Jul 25, 2014, 08:40 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 23, 2014 | Sale | $6.88 | 1,700 | 11,702 | 6,115,350 | Jul 25, 2014, 08:40 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 25, 2014 | Sale | $6.55 | 1,700 | 11,137 | 6,111,800 | Jul 25, 2014, 08:40 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 16, 2014 | Sale | $6.59 | 3,500 | 23,058 | 7,026,050 | Jul 18, 2014, 07:19 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 18, 2014 | Sale | $6.80 | 5,000 | 34,001 | 7,016,050 | Jul 18, 2014, 07:19 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 17, 2014 | Sale | $6.58 | 5,000 | 32,906 | 7,021,050 | Jul 18, 2014, 07:19 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 18, 2014 | Sale | $6.80 | 5,000 | 34,001 | 6,117,050 | Jul 18, 2014, 07:17 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 17, 2014 | Sale | $6.58 | 5,000 | 32,906 | 6,122,050 | Jul 18, 2014, 07:17 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 16, 2014 | Sale | $6.59 | 3,500 | 23,058 | 6,127,050 | Jul 18, 2014, 07:17 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 11, 2014 | Sale | $6.48 | 1,750 | 11,339 | 7,029,550 | Jul 11, 2014, 08:25 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 10, 2014 | Sale | $6.69 | 4,500 | 30,109 | 7,031,300 | Jul 11, 2014, 08:25 PM |
| ISIS PHARMACEUTICALS INC | Director | Jul 09, 2014 | Sale | $7.08 | 1,800 | 12,748 | 7,035,800 | Jul 11, 2014, 08:25 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 09, 2014 | Sale | $7.08 | 1,800 | 12,748 | 6,136,800 | Jul 11, 2014, 08:25 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 11, 2014 | Sale | $6.48 | 1,750 | 11,339 | 6,130,550 | Jul 11, 2014, 08:25 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 10, 2014 | Sale | $6.69 | 4,500 | 30,109 | 6,132,300 | Jul 11, 2014, 08:25 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 03, 2014 | Sale | $8.07 | 1,200 | 9,678 | 6,138,600 | Jul 07, 2014, 05:19 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jul 02, 2014 | Sale | $8.07 | 3,100 | 25,011 | 6,139,800 | Jul 07, 2014, 05:19 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Jul 03, 2014 | Sale | $8.07 | 1,200 | 9,678 | 7,037,600 | Jul 07, 2014, 05:14 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Jul 02, 2014 | Sale | $8.07 | 3,100 | 25,011 | 7,038,800 | Jul 07, 2014, 05:14 PM |
| Gibson Neil W | Chief Scientific Officer | Jul 01, 2014 | Option Exercise | $1.74 | 2,500 | 4,350 | 82,500 | Jul 02, 2014, 04:39 PM |
| Gibson Neil W | Chief Scientific Officer | Jul 01, 2014 | Sale | $8.10 | 2,500 | 20,260 | 80,000 | Jul 02, 2014, 04:39 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Jul 01, 2014 | Option Exercise | $0.38 | 3,505 | 1,332 | 3,505 | Jul 02, 2014, 04:35 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Jul 01, 2014 | Sale | $8.11 | 3,505 | 28,426 | 0 | Jul 02, 2014, 04:35 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Jun 27, 2014 | Sale | $7.91 | 3,150 | 24,931 | 7,041,900 | Jun 27, 2014, 07:00 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Jun 26, 2014 | Sale | $7.89 | 1,700 | 13,408 | 7,045,050 | Jun 27, 2014, 07:00 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Jun 25, 2014 | Sale | $7.84 | 2,750 | 21,566 | 7,046,750 | Jun 27, 2014, 07:00 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jun 26, 2014 | Sale | $7.89 | 1,700 | 13,408 | 6,146,050 | Jun 27, 2014, 06:45 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jun 25, 2014 | Sale | $7.84 | 2,750 | 21,566 | 6,147,750 | Jun 27, 2014, 06:45 PM |
| ALNYLAM PHARMACEUTICALS, INC. | 10% Owner | Jun 27, 2014 | Sale | $7.91 | 3,150 | 24,931 | 6,142,900 | Jun 27, 2014, 06:45 PM |
| Gibson Neil W | Chief Scientific Officer | Jun 17, 2014 | Option Exercise | $1.74 | 5,000 | 8,700 | 85,000 | Jun 18, 2014, 05:54 PM |
| Gibson Neil W | Chief Scientific Officer | Jun 17, 2014 | Sale | $8.05 | 5,000 | 40,227 | 80,000 | Jun 18, 2014, 05:54 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Jun 09, 2014 | Option Exercise | $0.38 | 3,505 | 1,332 | 3,505 | Jun 09, 2014, 07:31 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Jun 09, 2014 | Sale | $7.14 | 3,505 | 25,017 | 0 | Jun 09, 2014, 07:31 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | May 29, 2014 | Option Exercise | $0.38 | 887 | 337 | 887 | May 29, 2014, 07:57 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | May 28, 2014 | Option Exercise | $0.38 | 875 | 332 | 875 | May 29, 2014, 07:57 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | May 27, 2014 | Option Exercise | $0.38 | 1,743 | 662 | 1,743 | May 29, 2014, 07:57 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | May 29, 2014 | Sale | $7.00 | 887 | 6,209 | 0 | May 29, 2014, 07:57 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | May 28, 2014 | Sale | $7.00 | 875 | 6,126 | 0 | May 29, 2014, 07:57 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | May 27, 2014 | Sale | $7.00 | 1,743 | 12,203 | 0 | May 29, 2014, 07:57 PM |
| Gibson Neil W | Chief Scientific Officer | Apr 09, 2014 | Option Exercise | $1.74 | 2,500 | 4,350 | 82,500 | Apr 10, 2014, 02:51 PM |
| Gibson Neil W | Chief Scientific Officer | Apr 09, 2014 | Sale | $8.11 | 2,500 | 20,271 | 80,000 | Apr 10, 2014, 02:51 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Mar 06, 2014 | Option Exercise | $0.38 | 3,505 | 1,332 | 83,721 | Apr 09, 2014, 02:02 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Mar 06, 2014 | Sale | $7.60 | 3,505 | 26,623 | 80,216 | Apr 09, 2014, 02:02 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Mar 06, 2014 | Option Exercise | $0.38 | 3,505 | 1,332 | 83,721 | Mar 07, 2014, 02:33 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Mar 06, 2014 | Sale | $11.35 | 3,505 | 39,778 | 80,216 | Mar 07, 2014, 02:33 PM |
| Gibson Neil W | Chief Scientific Officer | Mar 06, 2014 | Option Exercise | $1.74 | 2,500 | 4,350 | 82,500 | Mar 07, 2014, 02:29 PM |
| Gibson Neil W | Chief Scientific Officer | Mar 06, 2014 | Sale | $11.37 | 2,500 | 28,428 | 80,000 | Mar 07, 2014, 02:29 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Feb 05, 2014 | Option Exercise | $0.38 | 3,505 | 1,332 | 83,721 | Feb 07, 2014, 03:09 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Feb 05, 2014 | Sale | $8.40 | 3,505 | 29,437 | 80,216 | Feb 07, 2014, 03:09 PM |
| Gibson Neil W | Chief Scientific Officer | Feb 06, 2014 | Option Exercise | $1.74 | 45,000 | 78,300 | 80,000 | Feb 07, 2014, 03:04 PM |
| Gibson Neil W | Chief Scientific Officer | Feb 05, 2014 | Option Exercise | $1.74 | 2,500 | 4,350 | 52,500 | Feb 07, 2014, 03:04 PM |
| Gibson Neil W | Chief Scientific Officer | Feb 05, 2014 | Sale | $8.38 | 17,500 | 146,706 | 35,000 | Feb 07, 2014, 03:04 PM |
| Sanofi | 10% Owner | Feb 04, 2014 | Buy | $7.67 | 1,303,780 | 9,999,993 | 5,053,779 | Feb 05, 2014, 03:38 PM |
| Gibson Neil W | Chief Scientific Officer | Jan 21, 2014 | Option Exercise | $2.66 | 4,421 | 11,760 | 54,421 | Jan 23, 2014, 02:33 PM |
| Gibson Neil W | Chief Scientific Officer | Jan 21, 2014 | Sale | $8.09 | 4,421 | 35,764 | 50,000 | Jan 23, 2014, 02:33 PM |
| Gibson Neil W | Chief Scientific Officer | Jan 17, 2014 | Option Exercise | $2.17 | 4,479 | 9,706 | 54,479 | Jan 21, 2014, 04:03 PM |
| Gibson Neil W | Chief Scientific Officer | Jan 17, 2014 | Sale | $8.15 | 4,479 | 36,494 | 50,000 | Jan 21, 2014, 04:03 PM |
| Gibson Neil W | Chief Scientific Officer | Jan 16, 2014 | Option Exercise | $1.74 | 1,100 | 1,914 | 51,100 | Jan 17, 2014, 01:35 PM |
| Gibson Neil W | Chief Scientific Officer | Jan 16, 2014 | Sale | $8.03 | 1,100 | 8,837 | 50,000 | Jan 17, 2014, 01:35 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Jan 02, 2014 | Option Exercise | $0.38 | 3,505 | 1,332 | 83,721 | Jan 02, 2014, 08:52 PM |
| XANTHOPOULOS KLEANTHIS G | President & CEO | Jan 02, 2014 | Sale | $7.25 | 3,505 | 25,408 | 80,216 | Jan 02, 2014, 08:52 PM |
| Gibson Neil W | Chief Scientific Officer | Feb 04, 2013 | Option Exercise | $1.74 | 50,000 | 87,000 | 50,000 | Feb 14, 2013, 09:08 PM |
| ISIS PHARMACEUTICALS INC | 10% Owner | Oct 10, 2012 | Buy | $4.00 | 750,000 | 3,000,000 | 7,049,500 | Oct 11, 2012, 07:56 PM |
| PARSHALL B LYNNE | Director | Oct 10, 2012 | Buy | $4.00 | 750,000 | 3,000,000 | 7,049,500 | Oct 11, 2012, 07:53 PM |
| CROOKE STANLEY T | Director | Oct 10, 2012 | Buy | $4.00 | 750,000 | 3,000,000 | 7,049,500 | Oct 11, 2012, 07:52 PM |
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FUNDS WITH A POSITION IN REGULUS THERAPEUTICS INC
| Fund | # Shares Owned | % of Portfolio | % Change | Investing Style |
|---|---|---|---|---|
| VIVO CAPITAL, LLC | 5,000,000 | 1.13% | New | Other |
| GEODE CAPITAL MANAGEMENT, LLC | 122,521 | 0.00002% | No change | Other |
| RENAISSANCE TECHNOLOGIES LLC | 54,600 | 0.00011% | 8.98% | Other |
| BLACKROCK INC. | 573 | 0% | -7.28% | Other |
CHANGE IN SHARES OUTSTANDING FOR REGULUS THERAPEUTICS INC
STOCK BUYBACKS FOR REGULUS THERAPEUTICS INC
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Period of Report: 12/31/2023
10-K/10-Q Filings: View
Previous Period
% Change in Shares
Quarter
09/30/2023
3.09%
1Q
06/30/2023
5.94%
2Q
03/31/2023
20.14%
3Q
12/31/2022
20.04%
4Q
09/30/2022
35.18%
5Q
06/30/2022
38.49%
6Q
03/31/2022
38.63%
7Q
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BUYBACK ANNOUNCEMENT(S) FOR REGULUS THERAPEUTICS INC
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