Odonate Therapeutics Inc. (ODT) NASDAQ
$1.12 - (-)
Market Cap: -
As of 01/14/22 12:00 AM EST. Market closed.
Odonate Therapeutics Inc. (ODT)
NASDAQ
$1.12
- (-)
Market Cap: -
As of 01/14/22 12:00 AM EST. Market closed.
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Odonate Therapeutics, Inc. is a pharmaceutical company dedicated to the development of best-in-class therapeutics that improve and extend the lives of patients with cancer. Odonate’s initial focus is on the development of tesetaxel, an investigational, orally administered chemotherapy agent that belongs to a class of drugs known as taxanes, which are widely used in the treatment of cancer. ... read more
COMPANY PROFILE
Sector
Manufacturing
Industry
Medicinal and Botanical Manufacturing
CEO Compensation (Base)
$1
CEO Compensation (Total)
$1
Sector
Manufacturing
Industry
Medicinal and Botanical Manufacturing
CEO Compensation (Base)
$1
CEO Compensation (Total)
$1
URL
Address
4747 Executive Dr, California, San Diego, 92121-3095.
PRICE CHART FOR ODONATE THERAPEUTICS INC
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NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
$1.16
Previous Close
$1.12
Days Range
- - -
52 week range
- - -
Volume
0
Avg. Volume (30 days)
0
Market Cap
-
Dividend Yield
-
P/E
-
Shares Outstanding
38,490,336
Open
$1.16
Previous Close
$1.12
Days Range
- - -
52 week range
- - -
Volume
0
Avg. Volume (30 days)
0
Market Cap
-
Dividend Yield
-
P/E
-
Shares Outstanding
38,490,336
FINANCIAL STATEMENTS FOR ODONATE THERAPEUTICS INC
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INSIDER TRANSACTIONS FOR ODONATE THERAPEUTICS INC
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| EcoR1 Capital, LLC | 10% Owner | Dec 01, 2021 | Buy | $1.66 | 185,941 | 308,662 | 5,701,669 | Dec 10, 2021, 06:50 PM |
| EcoR1 Capital, LLC | 10% Owner | Dec 10, 2021 | Sale | $1.65 | 5,545,000 | 9,147,420 | 545,000 | Dec 10, 2021, 06:50 PM |
| EcoR1 Capital, LLC | 10% Owner | Dec 09, 2021 | Sale | $1.82 | 156,669 | 284,981 | 5,545,000 | Dec 10, 2021, 06:50 PM |
| EcoR1 Capital, LLC | 10% Owner | Dec 01, 2021 | Sale | $1.66 | 185,941 | 308,662 | 5,701,669 | Dec 10, 2021, 06:50 PM |
| Boxer Capital, LLC | 10% Owner | Nov 24, 2021 | Sale | $1.57 | 200,000 | 313,680 | 4,207,086 | Nov 24, 2021, 06:00 PM |
| Boxer Capital, LLC | 10% Owner | Nov 22, 2021 | Sale | $1.55 | 200,000 | 309,660 | 4,407,086 | Nov 24, 2021, 06:00 PM |
| Davis Aaron I. | Director | Nov 19, 2021 | Sale | $1.84 | 150,000 | 276,285 | 4,607,086 | Nov 19, 2021, 07:22 PM |
| Davis Aaron I. | Director | Nov 19, 2021 | Sale | $1.92 | 30,000 | 57,495 | 445,756 | Nov 19, 2021, 07:22 PM |
| Davis Aaron I. | Director | Nov 18, 2021 | Sale | $1.95 | 250,000 | 487,250 | 4,757,086 | Nov 19, 2021, 07:22 PM |
| Davis Aaron I. | Director | Nov 17, 2021 | Sale | $2.17 | 600,000 | 1,299,240 | 5,007,086 | Nov 19, 2021, 07:22 PM |
| Davis Aaron I. | Director | Nov 17, 2021 | Sale | $2.23 | 170,000 | 379,678 | 475,756 | Nov 19, 2021, 07:22 PM |
| Boxer Capital, LLC | Director | Nov 19, 2021 | Sale | $1.84 | 150,000 | 276,285 | 4,607,086 | Nov 19, 2021, 07:21 PM |
| Boxer Capital, LLC | Director | Nov 18, 2021 | Sale | $1.95 | 250,000 | 487,250 | 4,757,086 | Nov 19, 2021, 07:21 PM |
| Boxer Capital, LLC | Director | Nov 17, 2021 | Sale | $2.17 | 600,000 | 1,299,240 | 5,007,086 | Nov 19, 2021, 07:21 PM |
| TANG KEVIN C | Chief Executive Officer | Nov 19, 2021 | Sale | $1.92 | 365,289 | 699,930 | 12,767,435 | Nov 19, 2021, 04:38 PM |
| TANG KEVIN C | Chief Executive Officer | Nov 18, 2021 | Sale | $1.90 | 1,094,265 | 2,081,879 | 14,014,566 | Nov 19, 2021, 04:38 PM |
| TANG KEVIN C | Chief Executive Officer | Nov 17, 2021 | Sale | $2.29 | 1,287,577 | 2,948,747 | 15,045,717 | Nov 19, 2021, 04:38 PM |
| Hearne Michael S | Chief Financial Officer | Mar 15, 2021 | Option Exercise | $16.22 | 37 | 600 | 2,620 | Mar 17, 2021, 04:04 PM |
| O'Connell Joseph P | Chief Medical Officer | Mar 15, 2021 | Option Exercise | $16.22 | 99 | 1,606 | 3,610 | Mar 17, 2021, 04:04 PM |
| Hearne Michael S | Chief Financial Officer | Feb 26, 2021 | Option Exercise | $17.89 | 34 | 608 | 2,583 | Mar 02, 2021, 04:03 PM |
| O'Connell Joseph P | Chief Medical Officer | Feb 26, 2021 | Option Exercise | $17.89 | 90 | 1,610 | 3,511 | Mar 02, 2021, 04:02 PM |
| Hearne Michael S | Chief Financial Officer | Feb 12, 2021 | Option Exercise | $21.19 | 28 | 593 | 2,549 | Feb 17, 2021, 04:07 PM |
| O'Connell Joseph P | Chief Medical Officer | Feb 12, 2021 | Option Exercise | $21.19 | 76 | 1,610 | 3,421 | Feb 17, 2021, 04:06 PM |
| Hearne Michael S | Chief Financial Officer | Jan 29, 2021 | Option Exercise | $19.64 | 31 | 609 | 2,521 | Feb 02, 2021, 04:10 PM |
| O'Connell Joseph P | Chief Medical Officer | Jan 29, 2021 | Option Exercise | $19.64 | 82 | 1,610 | 3,345 | Feb 02, 2021, 04:09 PM |
| Hearne Michael S | Chief Financial Officer | Jan 15, 2021 | Option Exercise | $16.99 | 35 | 595 | 2,490 | Jan 20, 2021, 04:01 PM |
| O'Connell Joseph P | Chief Medical Officer | Jan 15, 2021 | Option Exercise | $16.99 | 94 | 1,597 | 3,263 | Jan 20, 2021, 04:01 PM |
| Hearne Michael S | Chief Financial Officer | Dec 31, 2020 | Option Exercise | $16.32 | 350 | 5,712 | 2,455 | Jan 05, 2021, 04:06 PM |
| O'Connell Joseph P | Chief Medical Officer | Dec 31, 2020 | Option Exercise | $16.32 | 169 | 2,758 | 3,169 | Jan 05, 2021, 04:04 PM |
| Johnson Craig A | Director | Dec 29, 2020 | Buy | $17.00 | 3,000 | 51,000 | 3,000 | Dec 31, 2020, 04:01 PM |
| Boxer Capital, LLC | Director | Dec 30, 2020 | Buy | $17.46 | 100,000 | 1,746,380 | 5,607,086 | Dec 30, 2020, 06:19 PM |
| Boxer Capital, LLC | Director | Dec 28, 2020 | Buy | $17.06 | 300,000 | 5,117,048 | 5,507,086 | Dec 30, 2020, 06:19 PM |
| Davis Aaron I. | Director | Dec 30, 2020 | Buy | $17.46 | 100,000 | 1,746,380 | 5,607,086 | Dec 30, 2020, 06:18 PM |
| Davis Aaron I. | Director | Dec 29, 2020 | Buy | $17.11 | 225,000 | 3,849,548 | 5,507,086 | Dec 30, 2020, 06:18 PM |
| Davis Aaron I. | Director | Dec 28, 2020 | Buy | $16.90 | 75,000 | 1,267,500 | 5,282,086 | Dec 30, 2020, 06:18 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 22, 2020 | Buy | $14.87 | 74,502 | 1,107,587 | 15,375,428 | Dec 23, 2020, 04:41 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 21, 2020 | Buy | $14.58 | 62,144 | 905,767 | 15,300,926 | Dec 23, 2020, 04:41 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 23, 2020 | Buy | $15.58 | 139,138 | 2,167,853 | 15,514,566 | Dec 23, 2020, 04:41 PM |
| Hearne Michael S | Chief Financial Officer | Dec 15, 2020 | Option Exercise | $12.91 | 43 | 555 | 2,105 | Dec 17, 2020, 04:01 PM |
| O'Connell Joseph P | Chief Medical Officer | Dec 15, 2020 | Option Exercise | $12.91 | 121 | 1,562 | 3,000 | Dec 17, 2020, 04:01 PM |
| Hearne Michael S | Chief Financial Officer | Nov 30, 2020 | Option Exercise | $12.77 | 45 | 575 | 2,062 | Dec 02, 2020, 04:02 PM |
| O'Connell Joseph P | Chief Medical Officer | Nov 30, 2020 | Option Exercise | $12.77 | 122 | 1,558 | 2,879 | Dec 02, 2020, 04:02 PM |
| Lemkey John G | Chief Operating Officer | Nov 30, 2020 | Option Exercise | $12.77 | 12 | 153 | 3,457 | Dec 02, 2020, 04:01 PM |
| Hearne Michael S | Chief Financial Officer | Nov 13, 2020 | Option Exercise | $12.20 | 46 | 561 | 2,017 | Nov 17, 2020, 04:06 PM |
| O'Connell Joseph P | Chief Medical Officer | Nov 13, 2020 | Option Exercise | $12.20 | 128 | 1,562 | 2,757 | Nov 17, 2020, 04:06 PM |
| Lemkey John G | Chief Operating Officer | Nov 13, 2020 | Option Exercise | $12.20 | 96 | 1,171 | 3,445 | Nov 17, 2020, 04:04 PM |
| Hearne Michael S | Chief Financial Officer | Oct 30, 2020 | Option Exercise | $12.25 | 46 | 564 | 1,971 | Nov 03, 2020, 04:06 PM |
| O'Connell Joseph P | Chief Medical Officer | Oct 30, 2020 | Option Exercise | $12.25 | 127 | 1,556 | 2,629 | Nov 03, 2020, 04:06 PM |
| Lemkey John G | Chief Operating Officer | Oct 30, 2020 | Option Exercise | $12.25 | 96 | 1,176 | 3,349 | Nov 03, 2020, 04:05 PM |
| Hearne Michael S | Chief Financial Officer | Oct 15, 2020 | Option Exercise | $13.35 | 42 | 561 | 1,925 | Oct 19, 2020, 04:04 PM |
| O'Connell Joseph P | Chief Medical Officer | Oct 15, 2020 | Option Exercise | $13.35 | 117 | 1,562 | 2,502 | Oct 19, 2020, 04:01 PM |
| Lemkey John G | Chief Operating Officer | Oct 15, 2020 | Option Exercise | $13.35 | 88 | 1,175 | 3,253 | Oct 19, 2020, 04:01 PM |
| Hearne Michael S | Chief Financial Officer | Sep 30, 2020 | Option Exercise | $11.42 | 50 | 571 | 1,883 | Oct 02, 2020, 04:03 PM |
| O'Connell Joseph P | Chief Medical Officer | Sep 30, 2020 | Option Exercise | $11.42 | 82 | 936 | 2,385 | Oct 02, 2020, 04:02 PM |
| Lemkey John G | Chief Operating Officer | Sep 30, 2020 | Option Exercise | $11.42 | 102 | 1,165 | 3,165 | Oct 02, 2020, 04:02 PM |
| Davis Aaron I. | Director | Sep 29, 2020 | Buy | $14.08 | 122,000 | 1,717,760 | 5,207,086 | Sep 30, 2020, 04:36 PM |
| Davis Aaron I. | Director | Sep 28, 2020 | Buy | $13.03 | 93,200 | 1,214,396 | 5,085,086 | Sep 30, 2020, 04:36 PM |
| Boxer Capital, LLC | Director | Sep 29, 2020 | Buy | $14.08 | 122,000 | 1,717,760 | 5,207,086 | Sep 30, 2020, 04:31 PM |
| Boxer Capital, LLC | Director | Sep 28, 2020 | Buy | $13.03 | 93,200 | 1,214,396 | 5,085,086 | Sep 30, 2020, 04:31 PM |
| TANG KEVIN C | Chief Executive Officer | Sep 29, 2020 | Buy | $13.85 | 10,882 | 150,698 | 15,238,782 | Sep 30, 2020, 04:01 PM |
| TANG KEVIN C | Chief Executive Officer | Sep 28, 2020 | Buy | $13.06 | 100,000 | 1,305,710 | 15,227,900 | Sep 30, 2020, 04:01 PM |
| Hearne Michael S | Chief Financial Officer | Sep 15, 2020 | Option Exercise | $13.06 | 43 | 562 | 1,833 | Sep 17, 2020, 04:13 PM |
| O'Connell Joseph P | Chief Medical Officer | Sep 15, 2020 | Option Exercise | $13.06 | 72 | 940 | 2,303 | Sep 17, 2020, 04:12 PM |
| Lemkey John G | Chief Operating Officer | Sep 15, 2020 | Option Exercise | $13.06 | 90 | 1,175 | 3,063 | Sep 17, 2020, 04:09 PM |
| Davis Aaron I. | Director | Sep 09, 2020 | Buy | $15.20 | 81,100 | 1,232,720 | 4,991,886 | Sep 09, 2020, 05:59 PM |
| Davis Aaron I. | Director | Sep 08, 2020 | Buy | $14.69 | 18,800 | 276,172 | 4,910,786 | Sep 09, 2020, 05:59 PM |
| Davis Aaron I. | Director | Sep 04, 2020 | Buy | $14.89 | 125,100 | 1,862,739 | 4,891,986 | Sep 09, 2020, 05:59 PM |
| Boxer Capital, LLC | Director | Sep 09, 2020 | Buy | $15.20 | 81,100 | 1,232,720 | 4,991,886 | Sep 09, 2020, 05:59 PM |
| Boxer Capital, LLC | Director | Sep 08, 2020 | Buy | $14.69 | 18,800 | 276,172 | 4,910,786 | Sep 09, 2020, 05:59 PM |
| Boxer Capital, LLC | Director | Sep 04, 2020 | Buy | $14.89 | 125,100 | 1,862,739 | 4,891,986 | Sep 09, 2020, 05:59 PM |
| Hearne Michael S | Chief Financial Officer | Aug 31, 2020 | Option Exercise | $13.73 | 42 | 577 | 1,790 | Sep 02, 2020, 04:03 PM |
| O'Connell Joseph P | Chief Medical Officer | Aug 31, 2020 | Option Exercise | $13.73 | 69 | 947 | 2,231 | Sep 02, 2020, 04:02 PM |
| Lemkey John G | Chief Operating Officer | Aug 31, 2020 | Option Exercise | $13.73 | 87 | 1,195 | 2,973 | Sep 02, 2020, 04:00 PM |
| Boxer Capital, LLC | Director | Aug 28, 2020 | Buy | $14.25 | 1,403,509 | 20,000,003 | 4,766,886 | Sep 01, 2020, 04:30 PM |
| Davis Aaron I. | Director | Aug 28, 2020 | Buy | $14.25 | 1,403,509 | 20,000,003 | 4,766,886 | Sep 01, 2020, 04:30 PM |
| TANG KEVIN C | Chief Executive Officer | Aug 28, 2020 | Buy | $14.25 | 1,052,631 | 14,999,992 | 15,127,900 | Sep 01, 2020, 08:17 AM |
| Hearne Michael S | Chief Financial Officer | Aug 14, 2020 | Option Exercise | $30.71 | 18 | 553 | 1,748 | Aug 18, 2020, 04:03 PM |
| O'Connell Joseph P | Chief Medical Officer | Aug 14, 2020 | Option Exercise | $30.71 | 31 | 952 | 2,162 | Aug 18, 2020, 04:03 PM |
| Lemkey John G | Chief Operating Officer | Aug 14, 2020 | Option Exercise | $30.71 | 38 | 1,167 | 2,886 | Aug 18, 2020, 04:02 PM |
| Hearne Michael S | Chief Financial Officer | Jul 31, 2020 | Option Exercise | $30.91 | 18 | 556 | 1,730 | Aug 04, 2020, 04:03 PM |
| O'Connell Joseph P | Chief Medical Officer | Jul 31, 2020 | Option Exercise | $30.91 | 30 | 927 | 2,131 | Aug 04, 2020, 04:02 PM |
| Lemkey John G | Chief Operating Officer | Jul 31, 2020 | Option Exercise | $30.91 | 38 | 1,175 | 2,848 | Aug 04, 2020, 04:01 PM |
| Hearne Michael S | Chief Financial Officer | Jul 15, 2020 | Option Exercise | $34.99 | 17 | 595 | 1,712 | Jul 17, 2020, 04:04 PM |
| O'Connell Joseph P | Chief Medical Officer | Jul 15, 2020 | Option Exercise | $34.99 | 27 | 945 | 2,101 | Jul 17, 2020, 04:03 PM |
| Lemkey John G | Chief Operating Officer | Jul 15, 2020 | Option Exercise | $34.99 | 33 | 1,155 | 2,810 | Jul 17, 2020, 04:03 PM |
| Hearne Michael S | Chief Financial Officer | Jun 30, 2020 | Option Exercise | $35.99 | 15 | 540 | 1,695 | Jul 02, 2020, 04:25 PM |
| O'Connell Joseph P | Chief Medical Officer | Jun 30, 2020 | Option Exercise | $35.99 | 26 | 936 | 2,074 | Jul 02, 2020, 04:22 PM |
| Lemkey John G | Chief Operating Officer | Jun 30, 2020 | Option Exercise | $35.99 | 33 | 1,188 | 2,777 | Jul 02, 2020, 04:20 PM |
| Hearne Michael S | Chief Financial Officer | Jun 15, 2020 | Option Exercise | $34.21 | 17 | 582 | 1,680 | Jun 17, 2020, 04:27 PM |
| O'Connell Joseph P | Chief Medical Officer | Jun 15, 2020 | Option Exercise | $34.21 | 27 | 924 | 2,048 | Jun 17, 2020, 04:27 PM |
| Lemkey John G | Chief Operating Officer | Jun 15, 2020 | Option Exercise | $34.21 | 34 | 1,163 | 2,744 | Jun 17, 2020, 04:26 PM |
| Hearne Michael S | Chief Financial Officer | May 29, 2020 | Option Exercise | $27.77 | 40 | 1,111 | 1,663 | Jun 02, 2020, 04:04 PM |
| O'Connell Joseph P | Chief Medical Officer | May 29, 2020 | Option Exercise | $27.77 | 34 | 944 | 2,021 | Jun 02, 2020, 04:04 PM |
| Lemkey John G | Chief Operating Officer | May 29, 2020 | Option Exercise | $27.77 | 42 | 1,166 | 2,710 | Jun 02, 2020, 04:03 PM |
| Hearne Michael S | Chief Financial Officer | May 15, 2020 | Option Exercise | $24.00 | 47 | 1,128 | 1,623 | May 19, 2020, 08:14 PM |
| O'Connell Joseph P | Chief Medical Officer | May 15, 2020 | Option Exercise | $24.00 | 39 | 936 | 1,987 | May 19, 2020, 08:14 PM |
| Lemkey John G | Chief Operating Officer | May 15, 2020 | Option Exercise | $24.00 | 49 | 1,176 | 2,668 | May 19, 2020, 08:13 PM |
| Hearne Michael S | Chief Financial Officer | Apr 30, 2020 | Option Exercise | $23.93 | 47 | 1,125 | 1,576 | May 04, 2020, 04:03 PM |
| O'Connell Joseph P | Chief Medical Officer | Apr 30, 2020 | Option Exercise | $23.93 | 39 | 933 | 1,948 | May 04, 2020, 04:02 PM |
| Lemkey John G | Chief Operating Officer | Apr 30, 2020 | Option Exercise | $23.93 | 49 | 1,173 | 2,619 | May 04, 2020, 04:02 PM |
| Hearne Michael S | Chief Financial Officer | Apr 15, 2020 | Option Exercise | $22.82 | 50 | 1,141 | 1,529 | Apr 17, 2020, 04:07 PM |
| O'Connell Joseph P | Chief Medical Officer | Apr 15, 2020 | Option Exercise | $22.82 | 41 | 936 | 1,909 | Apr 17, 2020, 04:06 PM |
| Lemkey John G | Chief Operating Officer | Apr 15, 2020 | Option Exercise | $22.82 | 51 | 1,164 | 2,570 | Apr 17, 2020, 04:03 PM |
| Hearne Michael S | Chief Financial Officer | Mar 31, 2020 | Option Exercise | $23.47 | 24 | 563 | 1,479 | Apr 02, 2020, 04:13 PM |
| O'Connell Joseph P | Chief Medical Officer | Mar 31, 2020 | Option Exercise | $23.47 | 40 | 939 | 1,868 | Apr 02, 2020, 04:12 PM |
| Lemkey John G | Chief Operating Officer | Mar 31, 2020 | Option Exercise | $23.47 | 50 | 1,173 | 2,519 | Apr 02, 2020, 04:12 PM |
| Hearne Michael S | Chief Financial Officer | Mar 13, 2020 | Option Exercise | $19.59 | 29 | 568 | 1,455 | Mar 17, 2020, 04:17 PM |
| O'Connell Joseph P | Chief Medical Officer | Mar 13, 2020 | Option Exercise | $19.59 | 48 | 940 | 1,828 | Mar 17, 2020, 04:14 PM |
| Lemkey John G | Chief Operating Officer | Mar 13, 2020 | Option Exercise | $19.59 | 60 | 1,175 | 2,469 | Mar 17, 2020, 04:12 PM |
| Hearne Michael S | Chief Financial Officer | Feb 28, 2020 | Option Exercise | $25.15 | 22 | 553 | 1,426 | Mar 03, 2020, 04:05 PM |
| O'Connell Joseph P | Chief Medical Officer | Feb 28, 2020 | Option Exercise | $25.15 | 37 | 931 | 1,780 | Mar 03, 2020, 04:05 PM |
| Lemkey John G | Chief Operating Officer | Feb 28, 2020 | Option Exercise | $25.15 | 47 | 1,182 | 2,409 | Mar 03, 2020, 04:04 PM |
| Hearne Michael S | Chief Financial Officer | Feb 14, 2020 | Option Exercise | $26.73 | 21 | 561 | 1,404 | Feb 19, 2020, 04:12 PM |
| O'Connell Joseph P | Chief Medical Officer | Feb 14, 2020 | Option Exercise | $26.73 | 35 | 936 | 1,743 | Feb 19, 2020, 04:12 PM |
| Lemkey John G | Chief Operating Officer | Feb 14, 2020 | Option Exercise | $26.73 | 43 | 1,149 | 2,362 | Feb 19, 2020, 04:11 PM |
| Hearne Michael S | Chief Financial Officer | Jan 31, 2020 | Option Exercise | $24.82 | 23 | 571 | 1,383 | Feb 04, 2020, 04:31 PM |
| O'Connell Joseph P | Chief Medical Officer | Jan 31, 2020 | Option Exercise | $24.82 | 38 | 943 | 1,708 | Feb 04, 2020, 04:30 PM |
| Lemkey John G | Chief Operating Officer | Jan 31, 2020 | Option Exercise | $24.82 | 48 | 1,191 | 2,319 | Feb 04, 2020, 04:30 PM |
| Hearne Michael S | Chief Financial Officer | Jan 15, 2020 | Option Exercise | $23.15 | 24 | 556 | 1,360 | Jan 17, 2020, 04:02 PM |
| O'Connell Joseph P | Chief Medical Officer | Jan 15, 2020 | Option Exercise | $23.15 | 40 | 926 | 1,670 | Jan 17, 2020, 04:02 PM |
| Lemkey John G | Chief Operating Officer | Jan 15, 2020 | Option Exercise | $23.15 | 50 | 1,157 | 2,271 | Jan 17, 2020, 04:01 PM |
| Hearne Michael S | Chief Financial Officer | Dec 31, 2019 | Option Exercise | $27.58 | 20 | 552 | 1,336 | Jan 03, 2020, 04:04 PM |
| O'Connell Joseph P | Chief Medical Officer | Dec 31, 2019 | Option Exercise | $27.58 | 33 | 910 | 1,630 | Jan 03, 2020, 04:03 PM |
| Lemkey John G | Chief Operating Officer | Dec 31, 2019 | Option Exercise | $27.58 | 41 | 1,131 | 2,221 | Jan 03, 2020, 04:02 PM |
| Hearne Michael S | Chief Financial Officer | Dec 13, 2019 | Option Exercise | $24.62 | 22 | 542 | 1,316 | Dec 17, 2019, 04:05 PM |
| O'Connell Joseph P | Chief Medical Officer | Dec 13, 2019 | Option Exercise | $24.62 | 37 | 911 | 1,597 | Dec 17, 2019, 04:05 PM |
| Lemkey John G | Chief Operating Officer | Dec 13, 2019 | Option Exercise | $24.62 | 47 | 1,157 | 2,180 | Dec 17, 2019, 04:04 PM |
| Hearne Michael S | Chief Financial Officer | Nov 29, 2019 | Option Exercise | $29.22 | 19 | 555 | 1,294 | Dec 03, 2019, 04:02 PM |
| O'Connell Joseph P | Chief Medical Officer | Nov 29, 2019 | Option Exercise | $29.22 | 31 | 906 | 1,560 | Dec 03, 2019, 04:02 PM |
| Lemkey John G | Chief Operating Officer | Nov 29, 2019 | Option Exercise | $29.22 | 39 | 1,140 | 2,133 | Dec 03, 2019, 04:01 PM |
| Hearne Michael S | Chief Financial Officer | Nov 15, 2019 | Option Exercise | $28.14 | 19 | 535 | 1,275 | Nov 19, 2019, 06:04 PM |
| O'Connell Joseph P | Chief Medical Officer | Nov 15, 2019 | Option Exercise | $28.14 | 33 | 929 | 1,529 | Nov 19, 2019, 06:03 PM |
| Lemkey John G | Chief Operating Officer | Nov 15, 2019 | Option Exercise | $28.14 | 40 | 1,126 | 2,094 | Nov 19, 2019, 06:02 PM |
| Hearne Michael S | Chief Financial Officer | Oct 31, 2019 | Option Exercise | $27.00 | 21 | 567 | 1,256 | Nov 04, 2019, 04:11 PM |
| O'Connell Joseph P | Chief Medical Officer | Oct 31, 2019 | Option Exercise | $27.00 | 33 | 891 | 1,496 | Nov 04, 2019, 04:11 PM |
| Lemkey John G | Chief Operating Officer | Oct 31, 2019 | Option Exercise | $27.00 | 42 | 1,134 | 2,054 | Nov 04, 2019, 04:10 PM |
| Hearne Michael S | Chief Financial Officer | Oct 15, 2019 | Option Exercise | $24.23 | 22 | 533 | 1,235 | Oct 17, 2019, 05:46 PM |
| O'Connell Joseph P | Chief Medical Officer | Oct 15, 2019 | Option Exercise | $24.23 | 38 | 921 | 1,463 | Oct 17, 2019, 05:45 PM |
| Lemkey John G | Chief Operating Officer | Oct 15, 2019 | Option Exercise | $24.23 | 47 | 1,139 | 2,012 | Oct 17, 2019, 05:44 PM |
| Hearne Michael S | Chief Financial Officer | Sep 30, 2019 | Option Exercise | $22.13 | 25 | 553 | 1,213 | Oct 02, 2019, 04:02 PM |
| O'Connell Joseph P | Chief Medical Officer | Sep 30, 2019 | Option Exercise | $22.13 | 41 | 907 | 1,425 | Oct 02, 2019, 12:00 AM |
| Lemkey John G | Chief Operating Officer | Sep 30, 2019 | Option Exercise | $22.13 | 51 | 1,129 | 1,965 | Oct 02, 2019, 12:00 AM |
| Hearne Michael S | Chief Financial Officer | Sep 13, 2019 | Option Exercise | $24.11 | 23 | 555 | 1,188 | Sep 17, 2019, 07:24 PM |
| O'Connell Joseph P | Chief Medical Officer | Sep 13, 2019 | Option Exercise | $24.11 | 38 | 916 | 1,384 | Sep 17, 2019, 07:23 PM |
| Lemkey John G | Chief Operating Officer | Sep 13, 2019 | Option Exercise | $24.11 | 48 | 1,157 | 1,914 | Sep 17, 2019, 07:23 PM |
| Hearne Michael S | Chief Financial Officer | Aug 30, 2019 | Option Exercise | $26.19 | 21 | 550 | 1,165 | Sep 04, 2019, 04:18 PM |
| O'Connell Joseph P | Chief Medical Officer | Aug 30, 2019 | Option Exercise | $26.19 | 34 | 890 | 1,346 | Sep 04, 2019, 04:18 PM |
| Lemkey John G | Chief Operating Officer | Aug 30, 2019 | Option Exercise | $26.19 | 43 | 1,126 | 1,866 | Sep 04, 2019, 04:17 PM |
| Hearne Michael S | Chief Financial Officer | Aug 15, 2019 | Option Exercise | $28.42 | 19 | 540 | 1,144 | Aug 19, 2019, 04:12 PM |
| O'Connell Joseph P | Chief Medical Officer | Aug 15, 2019 | Option Exercise | $28.42 | 33 | 938 | 1,312 | Aug 19, 2019, 04:11 PM |
| Lemkey John G | Chief Operating Officer | Aug 15, 2019 | Option Exercise | $28.42 | 40 | 1,137 | 1,823 | Aug 19, 2019, 04:10 PM |
| Hearne Michael S | Chief Financial Officer | Jul 31, 2019 | Option Exercise | $34.64 | 16 | 554 | 1,125 | Aug 02, 2019, 04:05 PM |
| O'Connell Joseph P | Chief Medical Officer | Jul 31, 2019 | Option Exercise | $34.64 | 26 | 901 | 1,279 | Aug 02, 2019, 04:04 PM |
| Lemkey John G | Chief Operating Officer | Jul 31, 2019 | Option Exercise | $34.64 | 33 | 1,143 | 1,783 | Aug 02, 2019, 04:04 PM |
| Hearne Michael S | Chief Financial Officer | Jul 15, 2019 | Option Exercise | $29.89 | 18 | 538 | 1,109 | Jul 17, 2019, 06:53 PM |
| O'Connell Joseph P | Chief Medical Officer | Jul 15, 2019 | Option Exercise | $29.89 | 30 | 897 | 1,253 | Jul 17, 2019, 06:52 PM |
| Lemkey John G | Chief Operating Officer | Jul 15, 2019 | Option Exercise | $29.89 | 38 | 1,136 | 1,750 | Jul 17, 2019, 06:52 PM |
| Hearne Michael S | Chief Financial Officer | Jun 28, 2019 | Option Exercise | $31.19 | 17 | 530 | 1,091 | Jul 02, 2019, 06:40 PM |
| O'Connell Joseph P | Chief Medical Officer | Jun 28, 2019 | Option Exercise | $31.19 | 29 | 905 | 1,223 | Jul 02, 2019, 06:40 PM |
| Lemkey John G | Chief Operating Officer | Jun 28, 2019 | Option Exercise | $31.19 | 36 | 1,123 | 1,712 | Jul 02, 2019, 06:39 PM |
| Boxer Capital, LLC | 10% Owner | Jun 26, 2019 | Buy | $26.00 | 384,615 | 9,999,990 | 3,363,377 | Jun 28, 2019, 04:30 PM |
| Vacirca Jeff L | Director | Jun 26, 2019 | Buy | $26.00 | 19,231 | 500,006 | 23,231 | Jun 28, 2019, 04:03 PM |
| TANG KEVIN C | Chief Executive Officer | Jun 26, 2019 | Buy | $26.00 | 769,231 | 20,000,006 | 14,075,269 | Jun 28, 2019, 04:01 PM |
| TANG KEVIN C | Chief Executive Officer | Jun 17, 2019 | Buy | $26.81 | 10,042 | 269,231 | 13,284,688 | Jun 18, 2019, 09:43 PM |
| TANG KEVIN C | Chief Executive Officer | Jun 14, 2019 | Buy | $24.95 | 18,608 | 464,294 | 13,274,646 | Jun 18, 2019, 09:43 PM |
| TANG KEVIN C | Chief Executive Officer | Jun 18, 2019 | Buy | $26.89 | 21,350 | 574,020 | 13,306,038 | Jun 18, 2019, 09:43 PM |
| Hearne Michael S | Chief Financial Officer | Jun 14, 2019 | Option Exercise | $21.25 | 26 | 553 | 1,074 | Jun 18, 2019, 06:49 PM |
| O'Connell Joseph P | Chief Medical Officer | Jun 14, 2019 | Option Exercise | $21.25 | 43 | 914 | 1,194 | Jun 18, 2019, 06:48 PM |
| Lemkey John G | Chief Operating Officer | Jun 14, 2019 | Option Exercise | $21.25 | 54 | 1,148 | 1,676 | Jun 18, 2019, 06:48 PM |
| TANG KEVIN C | Chief Executive Officer | Jun 07, 2019 | Buy | $26.31 | 20,000 | 526,220 | 13,256,038 | Jun 10, 2019, 07:15 PM |
| TANG KEVIN C | Chief Executive Officer | Jun 06, 2019 | Buy | $27.73 | 56,308 | 1,561,237 | 13,236,038 | Jun 10, 2019, 07:15 PM |
| TANG KEVIN C | Chief Executive Officer | Jun 05, 2019 | Buy | $25.87 | 39,456 | 1,020,541 | 13,179,730 | Jun 05, 2019, 05:41 PM |
| TANG KEVIN C | Chief Executive Officer | Jun 04, 2019 | Buy | $24.92 | 38,950 | 970,772 | 13,140,274 | Jun 05, 2019, 05:41 PM |
| TANG KEVIN C | Chief Executive Officer | Jun 03, 2019 | Buy | $22.50 | 15,286 | 343,904 | 13,101,324 | Jun 05, 2019, 05:41 PM |
| Hearne Michael S | Chief Financial Officer | May 31, 2019 | Option Exercise | $18.27 | 30 | 548 | 1,048 | Jun 04, 2019, 04:33 PM |
| O'Connell Joseph P | Chief Medical Officer | May 31, 2019 | Option Exercise | $18.27 | 50 | 914 | 1,151 | Jun 04, 2019, 04:33 PM |
| Lemkey John G | Chief Operating Officer | May 31, 2019 | Option Exercise | $18.27 | 62 | 1,133 | 1,622 | Jun 04, 2019, 04:32 PM |
| Hearne Michael S | Chief Financial Officer | May 15, 2019 | Option Exercise | $18.87 | 29 | 547 | 1,018 | May 17, 2019, 06:05 PM |
| O'Connell Joseph P | Chief Medical Officer | May 15, 2019 | Option Exercise | $18.87 | 48 | 906 | 1,101 | May 17, 2019, 06:05 PM |
| Lemkey John G | Chief Operating Officer | May 15, 2019 | Option Exercise | $18.87 | 60 | 1,132 | 1,560 | May 17, 2019, 06:04 PM |
| Hearne Michael S | Chief Financial Officer | Apr 30, 2019 | Option Exercise | $16.71 | 33 | 551 | 989 | May 02, 2019, 07:58 PM |
| O'Connell Joseph P | Chief Medical Officer | Apr 30, 2019 | Option Exercise | $16.71 | 55 | 919 | 1,053 | May 02, 2019, 07:58 PM |
| Lemkey John G | Chief Operating Officer | Apr 30, 2019 | Option Exercise | $16.71 | 69 | 1,153 | 1,500 | May 02, 2019, 07:57 PM |
| Hearne Michael S | Chief Financial Officer | Apr 15, 2019 | Option Exercise | $21.24 | 26 | 552 | 956 | Apr 17, 2019, 04:04 PM |
| O'Connell Joseph P | Chief Medical Officer | Apr 15, 2019 | Option Exercise | $21.24 | 43 | 913 | 998 | Apr 17, 2019, 04:03 PM |
| Lemkey John G | Chief Operating Officer | Apr 15, 2019 | Option Exercise | $21.24 | 53 | 1,126 | 1,431 | Apr 17, 2019, 04:03 PM |
| Lemkey John G | Chief Operating Officer | Mar 29, 2019 | Option Exercise | $18.79 | 61 | 1,146 | 1,378 | Apr 02, 2019, 12:00 AM |
| Hearne Michael S | Chief Financial Officer | Mar 29, 2019 | Option Exercise | $18.79 | 29 | 545 | 930 | Apr 02, 2019, 12:00 AM |
| O'Connell Joseph P | Chief Medical Officer | Mar 29, 2019 | Option Exercise | $18.79 | 48 | 902 | 955 | Apr 02, 2019, 12:00 AM |
| O'Connell Joseph P | Chief Medical Officer | Mar 15, 2019 | Option Exercise | $20.19 | 45 | 909 | 907 | Mar 19, 2019, 04:05 PM |
| Hearne Michael S | Chief Financial Officer | Mar 15, 2019 | Option Exercise | $20.19 | 27 | 545 | 901 | Mar 19, 2019, 04:04 PM |
| Lemkey John G | Chief Operating Officer | Mar 15, 2019 | Option Exercise | $20.19 | 56 | 1,131 | 1,317 | Mar 19, 2019, 04:03 PM |
| TANG KEVIN C | Chief Executive Officer | Mar 08, 2019 | Buy | $18.75 | 100,000 | 1,874,583 | 13,086,038 | Mar 11, 2019, 05:42 PM |
| TANG KEVIN C | Chief Executive Officer | Mar 07, 2019 | Buy | $17.04 | 40,000 | 681,733 | 12,986,038 | Mar 11, 2019, 05:42 PM |
| Vacirca Jeff L | Director | Mar 04, 2019 | Buy | $17.00 | 3,000 | 51,000 | 4,000 | Mar 07, 2019, 04:57 PM |
| O'Connell Joseph P | Chief Medical Officer | Feb 28, 2019 | Option Exercise | $14.01 | 65 | 911 | 862 | Mar 04, 2019, 04:47 PM |
| Lemkey John G | Chief Operating Officer | Feb 28, 2019 | Option Exercise | $14.01 | 81 | 1,135 | 1,261 | Mar 04, 2019, 04:47 PM |
| Hearne Michael S | Chief Financial Officer | Feb 28, 2019 | Option Exercise | $14.01 | 39 | 546 | 874 | Mar 04, 2019, 12:00 AM |
| Hearne Michael S | Chief Financial Officer | Feb 15, 2019 | Option Exercise | $14.04 | 39 | 548 | 835 | Feb 20, 2019, 05:30 PM |
| O'Connell Joseph P | Chief Medical Officer | Feb 15, 2019 | Option Exercise | $14.04 | 65 | 913 | 797 | Feb 20, 2019, 05:29 PM |
| Lemkey John G | Chief Operating Officer | Feb 15, 2019 | Option Exercise | $14.04 | 81 | 1,137 | 1,180 | Feb 20, 2019, 05:29 PM |
| Hearne Michael S | Chief Financial Officer | Jan 31, 2019 | Option Exercise | $14.08 | 38 | 535 | 796 | Feb 04, 2019, 09:31 PM |
| O'Connell Joseph P | Chief Medical Officer | Jan 31, 2019 | Option Exercise | $14.08 | 64 | 901 | 732 | Feb 04, 2019, 09:31 PM |
| Lemkey John G | Chief Operating Officer | Jan 31, 2019 | Option Exercise | $14.08 | 81 | 1,140 | 1,099 | Feb 04, 2019, 09:30 PM |
| Hearne Michael S | Chief Financial Officer | Jan 15, 2019 | Option Exercise | $13.85 | 40 | 554 | 758 | Jan 17, 2019, 07:15 PM |
| O'Connell Joseph P | Chief Medical Officer | Jan 15, 2019 | Option Exercise | $13.85 | 66 | 914 | 668 | Jan 17, 2019, 07:12 PM |
| Lemkey John G | Chief Operating Officer | Jan 15, 2019 | Option Exercise | $13.85 | 82 | 1,136 | 1,018 | Jan 17, 2019, 07:11 PM |
| Hearne Michael S | Chief Financial Officer | Dec 31, 2018 | Option Exercise | $11.97 | 45 | 539 | 718 | Jan 03, 2019, 08:10 PM |
| O'Connell Joseph P | Chief Medical Officer | Dec 31, 2018 | Option Exercise | $11.97 | 74 | 886 | 602 | Jan 03, 2019, 08:09 PM |
| Lemkey John G | Chief Operating Officer | Dec 31, 2018 | Option Exercise | $11.97 | 70 | 838 | 936 | Jan 03, 2019, 08:09 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 31, 2018 | Buy | $13.68 | 33,700 | 460,929 | 12,946,038 | Dec 31, 2018, 05:17 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 28, 2018 | Buy | $12.69 | 20,000 | 253,863 | 12,912,338 | Dec 31, 2018, 05:17 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 27, 2018 | Buy | $12.03 | 10,000 | 120,315 | 12,892,338 | Dec 31, 2018, 05:17 PM |
| Davis Aaron I. | Director | Dec 21, 2018 | Buy | $13.47 | 100,000 | 1,347,015 | 2,953,762 | Dec 27, 2018, 05:01 PM |
| Davis Aaron I. | Director | Dec 26, 2018 | Buy | $12.47 | 25,000 | 311,815 | 2,978,762 | Dec 27, 2018, 05:01 PM |
| Boxer Capital, LLC | Director | Dec 26, 2018 | Buy | $12.47 | 25,000 | 311,815 | 2,978,762 | Dec 27, 2018, 05:00 PM |
| Boxer Capital, LLC | Director | Dec 21, 2018 | Buy | $13.47 | 100,000 | 1,347,015 | 2,953,762 | Dec 27, 2018, 05:00 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 26, 2018 | Buy | $12.28 | 30,000 | 368,287 | 12,882,338 | Dec 26, 2018, 06:21 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 21, 2018 | Buy | $12.79 | 20,000 | 255,828 | 12,852,338 | Dec 26, 2018, 06:21 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 20, 2018 | Buy | $13.17 | 10,000 | 131,742 | 12,832,338 | Dec 26, 2018, 06:21 PM |
| Hearne Michael S | Chief Financial Officer | Dec 14, 2018 | Option Exercise | $12.85 | 42 | 540 | 673 | Dec 18, 2018, 06:00 PM |
| O'Connell Joseph P | Chief Medical Officer | Dec 14, 2018 | Option Exercise | $12.85 | 68 | 874 | 528 | Dec 18, 2018, 06:00 PM |
| Lemkey John G | Chief Operating Officer | Dec 14, 2018 | Option Exercise | $12.85 | 64 | 822 | 866 | Dec 18, 2018, 05:59 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 18, 2018 | Buy | $14.28 | 11,704 | 167,189 | 12,822,338 | Dec 18, 2018, 05:58 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 17, 2018 | Buy | $14.68 | 18,296 | 268,612 | 12,810,634 | Dec 18, 2018, 05:58 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 14, 2018 | Buy | $15.08 | 10,000 | 150,838 | 12,792,338 | Dec 18, 2018, 05:58 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 12, 2018 | Buy | $15.74 | 14,550 | 228,946 | 12,782,338 | Dec 13, 2018, 08:18 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 11, 2018 | Buy | $15.25 | 5,450 | 83,128 | 12,767,788 | Dec 13, 2018, 08:18 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 06, 2018 | Buy | $14.63 | 10,500 | 153,573 | 12,752,838 | Dec 10, 2018, 06:24 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 07, 2018 | Buy | $14.98 | 9,500 | 142,291 | 12,762,338 | Dec 10, 2018, 06:24 PM |
| Hearne Michael S | Chief Financial Officer | Nov 30, 2018 | Option Exercise | $13.40 | 40 | 536 | 631 | Dec 04, 2018, 06:27 PM |
| O'Connell Joseph P | Chief Medical Officer | Nov 30, 2018 | Option Exercise | $13.40 | 66 | 884 | 460 | Dec 04, 2018, 06:26 PM |
| Lemkey John G | Chief Operating Officer | Nov 30, 2018 | Option Exercise | $13.40 | 63 | 844 | 802 | Dec 04, 2018, 06:25 PM |
| TANG KEVIN C | Chief Executive Officer | Nov 27, 2018 | Buy | $15.64 | 3,063 | 47,912 | 12,742,338 | Nov 29, 2018, 04:34 PM |
| TANG KEVIN C | Chief Executive Officer | Nov 23, 2018 | Buy | $15.25 | 4,644 | 70,830 | 12,732,338 | Nov 26, 2018, 07:49 PM |
| TANG KEVIN C | Chief Executive Officer | Nov 21, 2018 | Buy | $15.15 | 5,356 | 81,141 | 12,727,694 | Nov 26, 2018, 07:49 PM |
| TANG KEVIN C | Chief Executive Officer | Nov 26, 2018 | Buy | $15.43 | 6,937 | 107,046 | 12,739,275 | Nov 26, 2018, 07:49 PM |
| O'Connell Joseph P | Chief Medical Officer | Nov 15, 2018 | Option Exercise | $14.04 | 63 | 885 | 394 | Nov 19, 2018, 07:18 PM |
| Lemkey John G | Chief Financial Officer | Nov 15, 2018 | Option Exercise | $14.04 | 59 | 828 | 739 | Nov 19, 2018, 07:17 PM |
| TANG KEVIN C | Chief Executive Officer | Nov 01, 2018 | Buy | $14.87 | 10,000 | 148,727 | 12,722,338 | Nov 05, 2018, 09:31 PM |
| O'Connell Joseph P | Chief Medical Officer | Oct 31, 2018 | Option Exercise | $12.33 | 72 | 888 | 331 | Nov 02, 2018, 05:21 PM |
| Lemkey John G | Chief Financial Officer | Oct 31, 2018 | Option Exercise | $12.33 | 67 | 826 | 680 | Nov 02, 2018, 05:20 PM |
| TANG KEVIN C | Chief Executive Officer | Oct 29, 2018 | Buy | $14.96 | 10,000 | 149,642 | 12,712,338 | Oct 30, 2018, 04:24 PM |
| TANG KEVIN C | Chief Executive Officer | Oct 26, 2018 | Buy | $15.85 | 235 | 3,725 | 12,702,338 | Oct 30, 2018, 04:24 PM |
| Davis Aaron I. | Director | Oct 24, 2018 | Buy | $14.72 | 26,824 | 394,753 | 2,853,762 | Oct 26, 2018, 04:32 PM |
| Boxer Capital, LLC | Director | Oct 24, 2018 | Buy | $14.72 | 26,824 | 394,753 | 2,853,762 | Oct 26, 2018, 04:30 PM |
| TANG KEVIN C | Chief Executive Officer | Oct 25, 2018 | Buy | $15.78 | 9,765 | 154,059 | 12,702,103 | Oct 25, 2018, 07:31 PM |
| TANG KEVIN C | Chief Executive Officer | Oct 24, 2018 | Buy | $14.92 | 13,313 | 198,632 | 12,692,338 | Oct 25, 2018, 07:31 PM |
| TANG KEVIN C | Chief Executive Officer | Oct 23, 2018 | Buy | $15.44 | 16,687 | 257,609 | 12,679,025 | Oct 25, 2018, 07:31 PM |
| O'Connell Joseph P | Chief Medical Officer | Oct 15, 2018 | Option Exercise | $13.68 | 64 | 876 | 259 | Oct 17, 2018, 04:01 PM |
| Lemkey John G | Chief Financial Officer | Oct 15, 2018 | Option Exercise | $13.68 | 61 | 834 | 613 | Oct 17, 2018, 04:01 PM |
| O'Connell Joseph P | Chief Medical Officer | Sep 28, 2018 | Option Exercise | $16.50 | 18 | 297 | 195 | Oct 02, 2018, 04:04 PM |
| Lemkey John G | Chief Financial Officer | Sep 28, 2018 | Option Exercise | $16.50 | 51 | 842 | 552 | Oct 02, 2018, 04:03 PM |
| TANG KEVIN C | Chief Executive Officer | Sep 28, 2018 | Buy | $19.24 | 33,801 | 650,378 | 12,662,338 | Oct 01, 2018, 04:23 PM |
| TANG KEVIN C | Chief Executive Officer | Sep 27, 2018 | Buy | $18.70 | 6,199 | 115,929 | 12,628,537 | Oct 01, 2018, 04:23 PM |
| TANG KEVIN C | Chief Executive Officer | Sep 26, 2018 | Buy | $19.07 | 10,000 | 190,664 | 12,622,338 | Sep 26, 2018, 05:16 PM |
| TANG KEVIN C | Chief Executive Officer | Sep 25, 2018 | Buy | $19.65 | 10,000 | 196,477 | 12,612,338 | Sep 26, 2018, 05:16 PM |
| TANG KEVIN C | Chief Executive Officer | Sep 24, 2018 | Buy | $20.14 | 20,000 | 402,832 | 12,602,338 | Sep 26, 2018, 05:16 PM |
| TANG KEVIN C | Chief Executive Officer | Sep 20, 2018 | Buy | $20.11 | 27,983 | 562,736 | 12,582,338 | Sep 20, 2018, 08:01 PM |
| TANG KEVIN C | Chief Executive Officer | Sep 19, 2018 | Buy | $19.34 | 12,017 | 232,374 | 12,554,355 | Sep 20, 2018, 08:01 PM |
| TANG KEVIN C | Chief Executive Officer | Sep 18, 2018 | Buy | $19.28 | 50,000 | 964,186 | 12,542,338 | Sep 20, 2018, 08:01 PM |
| O'Connell Joseph P | Chief Medical Officer | Sep 14, 2018 | Option Exercise | $16.26 | 18 | 293 | 177 | Sep 18, 2018, 04:02 PM |
| Lemkey John G | Chief Financial Officer | Sep 14, 2018 | Option Exercise | $16.26 | 51 | 829 | 501 | Sep 18, 2018, 04:02 PM |
| O'Connell Joseph P | Chief Medical Officer | Aug 31, 2018 | Option Exercise | $16.31 | 18 | 294 | 159 | Sep 05, 2018, 04:01 PM |
| Lemkey John G | Chief Financial Officer | Aug 31, 2018 | Option Exercise | $16.31 | 51 | 832 | 450 | Sep 05, 2018, 04:01 PM |
| TANG KEVIN C | Chief Executive Officer | Aug 21, 2018 | Buy | $19.47 | 7,505 | 146,151 | 12,492,338 | Aug 23, 2018, 06:06 PM |
| TANG KEVIN C | Chief Executive Officer | Aug 16, 2018 | Buy | $19.65 | 37,190 | 730,681 | 12,472,338 | Aug 20, 2018, 06:10 PM |
| TANG KEVIN C | Chief Executive Officer | Aug 20, 2018 | Buy | $18.96 | 10,108 | 191,613 | 12,484,833 | Aug 20, 2018, 06:10 PM |
| TANG KEVIN C | Chief Executive Officer | Aug 17, 2018 | Buy | $19.26 | 2,387 | 45,980 | 12,474,725 | Aug 20, 2018, 06:10 PM |
| O'Connell Joseph P | Chief Medical Officer | Aug 15, 2018 | Option Exercise | $15.93 | 19 | 303 | 141 | Aug 17, 2018, 06:22 PM |
| Lemkey John G | Chief Financial Officer | Aug 15, 2018 | Option Exercise | $15.93 | 53 | 844 | 399 | Aug 17, 2018, 06:21 PM |
| TANG KEVIN C | Chief Executive Officer | Aug 15, 2018 | Buy | $19.04 | 9,416 | 179,242 | 12,435,148 | Aug 15, 2018, 05:42 PM |
| TANG KEVIN C | Chief Executive Officer | Aug 14, 2018 | Buy | $18.98 | 6,603 | 125,352 | 12,425,732 | Aug 15, 2018, 05:42 PM |
| TANG KEVIN C | Chief Executive Officer | Aug 13, 2018 | Buy | $18.72 | 6,791 | 127,111 | 12,419,129 | Aug 15, 2018, 05:42 PM |
| O'Connell Joseph P | Chief Medical Officer | Jul 31, 2018 | Option Exercise | $16.80 | 17 | 286 | 122 | Aug 02, 2018, 04:02 PM |
| Lemkey John G | Chief Financial Officer | Jul 31, 2018 | Option Exercise | $16.80 | 49 | 823 | 346 | Aug 02, 2018, 04:01 PM |
| O'Connell Joseph P | Chief Medical Officer | Jul 13, 2018 | Option Exercise | $20.36 | 15 | 305 | 105 | Jul 17, 2018, 04:01 PM |
| Lemkey John G | Chief Financial Officer | Jul 13, 2018 | Option Exercise | $20.36 | 41 | 835 | 297 | Jul 17, 2018, 04:01 PM |
| O'Connell Joseph P | Chief Medical Officer | Jun 29, 2018 | Option Exercise | $18.77 | 16 | 300 | 90 | Jul 03, 2018, 01:15 PM |
| Lemkey John G | Chief Financial Officer | Jun 29, 2018 | Option Exercise | $18.77 | 45 | 845 | 256 | Jul 03, 2018, 01:14 PM |
| O'Connell Joseph P | Chief Medical Officer | Jun 15, 2018 | Option Exercise | $22.54 | 13 | 293 | 74 | Jun 19, 2018, 04:06 PM |
| Lemkey John G | Chief Financial Officer | Jun 15, 2018 | Option Exercise | $22.54 | 37 | 834 | 211 | Jun 19, 2018, 04:05 PM |
| O'Connell Joseph P | Chief Medical Officer | May 31, 2018 | Option Exercise | $20.39 | 14 | 285 | 61 | Jun 04, 2018, 04:01 PM |
| Lemkey John G | Chief Financial Officer | May 31, 2018 | Option Exercise | $20.39 | 40 | 816 | 174 | Jun 04, 2018, 04:00 PM |
| O'Connell Joseph P | Chief Medical Officer | May 15, 2018 | Option Exercise | $19.69 | 15 | 295 | 47 | May 17, 2018, 04:05 PM |
| Lemkey John G | Chief Financial Officer | May 15, 2018 | Option Exercise | $19.69 | 43 | 847 | 134 | May 17, 2018, 04:04 PM |
| O'Connell Joseph P | Chief Medical Officer | Apr 30, 2018 | Option Exercise | $17.92 | 17 | 305 | 32 | May 02, 2018, 04:23 PM |
| Lemkey John G | Chief Financial Officer | Apr 30, 2018 | Option Exercise | $17.92 | 46 | 824 | 91 | May 02, 2018, 04:22 PM |
| O'Connell Joseph P | Chief Medical Officer | Apr 13, 2018 | Option Exercise | $18.41 | 15 | 276 | 15 | Apr 17, 2018, 04:16 PM |
| Lemkey John G | Chief Financial Officer | Apr 13, 2018 | Option Exercise | $18.41 | 45 | 828 | 45 | Apr 17, 2018, 04:15 PM |
| Boxer Capital, LLC | Director | Mar 26, 2018 | Buy | $22.41 | 33,650 | 754,096 | 2,826,938 | Mar 26, 2018, 06:59 PM |
| Boxer Capital, LLC | Director | Mar 23, 2018 | Buy | $23.96 | 42,943 | 1,028,914 | 2,793,288 | Mar 26, 2018, 06:59 PM |
| Boxer Capital, LLC | Director | Mar 22, 2018 | Buy | $20.94 | 23,407 | 490,143 | 2,750,345 | Mar 26, 2018, 06:59 PM |
| Davis Aaron I. | Director | Mar 23, 2018 | Buy | $23.96 | 42,943 | 1,028,914 | 2,793,288 | Mar 26, 2018, 06:56 PM |
| Davis Aaron I. | Director | Mar 22, 2018 | Buy | $20.94 | 23,407 | 490,143 | 2,750,345 | Mar 26, 2018, 06:56 PM |
| Davis Aaron I. | Director | Mar 26, 2018 | Buy | $22.41 | 33,650 | 754,096 | 2,826,938 | Mar 26, 2018, 06:56 PM |
| TANG KEVIN C | Chief Executive Officer | Mar 01, 2018 | Buy | $27.61 | 4,401 | 121,499 | 12,412,338 | Mar 02, 2018, 05:57 PM |
| TANG KEVIN C | Chief Executive Officer | Feb 28, 2018 | Buy | $27.33 | 9,649 | 263,683 | 12,407,937 | Mar 02, 2018, 05:57 PM |
| TANG KEVIN C | Chief Executive Officer | Feb 23, 2018 | Buy | $27.99 | 2,175 | 60,887 | 12,371,851 | Feb 27, 2018, 04:52 PM |
| TANG KEVIN C | Chief Executive Officer | Feb 27, 2018 | Buy | $27.11 | 12,591 | 341,285 | 12,398,288 | Feb 27, 2018, 04:52 PM |
| TANG KEVIN C | Chief Executive Officer | Feb 26, 2018 | Buy | $27.62 | 13,846 | 382,467 | 12,385,697 | Feb 27, 2018, 04:52 PM |
| TANG KEVIN C | Chief Executive Officer | Feb 22, 2018 | Buy | $27.57 | 17,338 | 478,065 | 12,369,676 | Feb 22, 2018, 06:17 PM |
| TANG KEVIN C | Chief Executive Officer | Feb 21, 2018 | Buy | $27.89 | 13,432 | 374,660 | 12,352,338 | Feb 22, 2018, 06:17 PM |
| TANG KEVIN C | Chief Executive Officer | Feb 20, 2018 | Buy | $25.15 | 8,313 | 209,086 | 12,338,906 | Feb 22, 2018, 06:17 PM |
| TANG KEVIN C | Chief Executive Officer | Feb 16, 2018 | Buy | $24.06 | 57,364 | 1,380,447 | 12,330,593 | Feb 16, 2018, 06:47 PM |
| TANG KEVIN C | Chief Executive Officer | Feb 15, 2018 | Buy | $21.98 | 34,943 | 768,075 | 12,273,229 | Feb 16, 2018, 06:47 PM |
| TANG KEVIN C | Chief Executive Officer | Feb 14, 2018 | Buy | $20.39 | 35,948 | 732,822 | 12,238,286 | Feb 16, 2018, 06:47 PM |
| Vacirca Jeff L | Director | Dec 12, 2017 | Buy | $23.30 | 1,000 | 23,300 | 1,000 | Dec 14, 2017, 08:01 PM |
| Davis Aaron I. | Director | Dec 06, 2017 | Buy | $24.00 | 416,666 | 9,999,984 | 2,726,938 | Dec 08, 2017, 05:21 PM |
| Boxer Capital, LLC | Director | Dec 06, 2017 | Buy | $24.00 | 416,666 | 9,999,984 | 2,726,938 | Dec 08, 2017, 05:19 PM |
| TANG KEVIN C | Chief Executive Officer | Dec 07, 2017 | Buy | $24.00 | 1,291,666 | 30,999,984 | 12,202,338 | Dec 08, 2017, 09:15 AM |
Load More Insider Transactions
Buy
Sale
Option Exercise
| Owner | Relationship | Date | Value($) |
| EcoR1 Capital, LLC | 10% Owner | 12/01/2021 | 308,662 |
| EcoR1 Capital, LLC | 10% Owner | 12/10/2021 | 9,147,420 |
| EcoR1 Capital, LLC | 10% Owner | 12/09/2021 | 284,981 |
| EcoR1 Capital, LLC | 10% Owner | 12/01/2021 | 308,662 |
| Boxer Capital, LLC | 10% Owner | 11/24/2021 | 313,680 |
| Boxer Capital, LLC | 10% Owner | 11/22/2021 | 309,660 |
| Davis Aaron I. | Director | 11/19/2021 | 276,285 |
| Davis Aaron I. | Director | 11/19/2021 | 57,495 |
| Davis Aaron I. | Director | 11/18/2021 | 487,250 |
| Davis Aaron I. | Director | 11/17/2021 | 1,299,240 |
| Davis Aaron I. | Director | 11/17/2021 | 379,678 |
| Boxer Capital, LLC | Director | 11/19/2021 | 276,285 |
| Boxer Capital, LLC | Director | 11/18/2021 | 487,250 |
| Boxer Capital, LLC | Director | 11/17/2021 | 1,299,240 |
| TANG KEVIN C | Chief Executive Officer | 11/19/2021 | 699,930 |
| TANG KEVIN C | Chief Executive Officer | 11/18/2021 | 2,081,879 |
| TANG KEVIN C | Chief Executive Officer | 11/17/2021 | 2,948,747 |
| Hearne Michael S | Chief Financial Officer | 03/15/2021 | 600 |
| O'Connell Joseph P | Chief Medical Officer | 03/15/2021 | 1,606 |
| Hearne Michael S | Chief Financial Officer | 02/26/2021 | 608 |
| O'Connell Joseph P | Chief Medical Officer | 02/26/2021 | 1,610 |
| Hearne Michael S | Chief Financial Officer | 02/12/2021 | 593 |
| O'Connell Joseph P | Chief Medical Officer | 02/12/2021 | 1,610 |
| Hearne Michael S | Chief Financial Officer | 01/29/2021 | 609 |
| O'Connell Joseph P | Chief Medical Officer | 01/29/2021 | 1,610 |
| Hearne Michael S | Chief Financial Officer | 01/15/2021 | 595 |
| O'Connell Joseph P | Chief Medical Officer | 01/15/2021 | 1,597 |
| Hearne Michael S | Chief Financial Officer | 12/31/2020 | 5,712 |
| O'Connell Joseph P | Chief Medical Officer | 12/31/2020 | 2,758 |
| Johnson Craig A | Director | 12/29/2020 | 51,000 |
| Boxer Capital, LLC | Director | 12/30/2020 | 1,746,380 |
| Boxer Capital, LLC | Director | 12/28/2020 | 5,117,048 |
| Davis Aaron I. | Director | 12/30/2020 | 1,746,380 |
| Davis Aaron I. | Director | 12/29/2020 | 3,849,548 |
| Davis Aaron I. | Director | 12/28/2020 | 1,267,500 |
| TANG KEVIN C | Chief Executive Officer | 12/22/2020 | 1,107,587 |
| TANG KEVIN C | Chief Executive Officer | 12/21/2020 | 905,767 |
| TANG KEVIN C | Chief Executive Officer | 12/23/2020 | 2,167,853 |
| Hearne Michael S | Chief Financial Officer | 12/15/2020 | 555 |
| O'Connell Joseph P | Chief Medical Officer | 12/15/2020 | 1,562 |
| Hearne Michael S | Chief Financial Officer | 11/30/2020 | 575 |
| O'Connell Joseph P | Chief Medical Officer | 11/30/2020 | 1,558 |
| Lemkey John G | Chief Operating Officer | 11/30/2020 | 153 |
| Hearne Michael S | Chief Financial Officer | 11/13/2020 | 561 |
| O'Connell Joseph P | Chief Medical Officer | 11/13/2020 | 1,562 |
| Lemkey John G | Chief Operating Officer | 11/13/2020 | 1,171 |
| Hearne Michael S | Chief Financial Officer | 10/30/2020 | 564 |
| O'Connell Joseph P | Chief Medical Officer | 10/30/2020 | 1,556 |
| Lemkey John G | Chief Operating Officer | 10/30/2020 | 1,176 |
| Hearne Michael S | Chief Financial Officer | 10/15/2020 | 561 |
| O'Connell Joseph P | Chief Medical Officer | 10/15/2020 | 1,562 |
| Lemkey John G | Chief Operating Officer | 10/15/2020 | 1,175 |
| Hearne Michael S | Chief Financial Officer | 09/30/2020 | 571 |
| O'Connell Joseph P | Chief Medical Officer | 09/30/2020 | 936 |
| Lemkey John G | Chief Operating Officer | 09/30/2020 | 1,165 |
| Davis Aaron I. | Director | 09/29/2020 | 1,717,760 |
| Davis Aaron I. | Director | 09/28/2020 | 1,214,396 |
| Boxer Capital, LLC | Director | 09/29/2020 | 1,717,760 |
| Boxer Capital, LLC | Director | 09/28/2020 | 1,214,396 |
| TANG KEVIN C | Chief Executive Officer | 09/29/2020 | 150,698 |
| TANG KEVIN C | Chief Executive Officer | 09/28/2020 | 1,305,710 |
| Hearne Michael S | Chief Financial Officer | 09/15/2020 | 562 |
| O'Connell Joseph P | Chief Medical Officer | 09/15/2020 | 940 |
| Lemkey John G | Chief Operating Officer | 09/15/2020 | 1,175 |
| Davis Aaron I. | Director | 09/09/2020 | 1,232,720 |
| Davis Aaron I. | Director | 09/08/2020 | 276,172 |
| Davis Aaron I. | Director | 09/04/2020 | 1,862,739 |
| Boxer Capital, LLC | Director | 09/09/2020 | 1,232,720 |
| Boxer Capital, LLC | Director | 09/08/2020 | 276,172 |
| Boxer Capital, LLC | Director | 09/04/2020 | 1,862,739 |
| Hearne Michael S | Chief Financial Officer | 08/31/2020 | 577 |
| O'Connell Joseph P | Chief Medical Officer | 08/31/2020 | 947 |
| Lemkey John G | Chief Operating Officer | 08/31/2020 | 1,195 |
| Boxer Capital, LLC | Director | 08/28/2020 | 20,000,003 |
| Davis Aaron I. | Director | 08/28/2020 | 20,000,003 |
| TANG KEVIN C | Chief Executive Officer | 08/28/2020 | 14,999,992 |
| Hearne Michael S | Chief Financial Officer | 08/14/2020 | 553 |
| O'Connell Joseph P | Chief Medical Officer | 08/14/2020 | 952 |
| Lemkey John G | Chief Operating Officer | 08/14/2020 | 1,167 |
| Hearne Michael S | Chief Financial Officer | 07/31/2020 | 556 |
| O'Connell Joseph P | Chief Medical Officer | 07/31/2020 | 927 |
| Lemkey John G | Chief Operating Officer | 07/31/2020 | 1,175 |
| Hearne Michael S | Chief Financial Officer | 07/15/2020 | 595 |
| O'Connell Joseph P | Chief Medical Officer | 07/15/2020 | 945 |
| Lemkey John G | Chief Operating Officer | 07/15/2020 | 1,155 |
| Hearne Michael S | Chief Financial Officer | 06/30/2020 | 540 |
| O'Connell Joseph P | Chief Medical Officer | 06/30/2020 | 936 |
| Lemkey John G | Chief Operating Officer | 06/30/2020 | 1,188 |
| Hearne Michael S | Chief Financial Officer | 06/15/2020 | 582 |
| O'Connell Joseph P | Chief Medical Officer | 06/15/2020 | 924 |
| Lemkey John G | Chief Operating Officer | 06/15/2020 | 1,163 |
| Hearne Michael S | Chief Financial Officer | 05/29/2020 | 1,111 |
| O'Connell Joseph P | Chief Medical Officer | 05/29/2020 | 944 |
| Lemkey John G | Chief Operating Officer | 05/29/2020 | 1,166 |
| Hearne Michael S | Chief Financial Officer | 05/15/2020 | 1,128 |
| O'Connell Joseph P | Chief Medical Officer | 05/15/2020 | 936 |
| Lemkey John G | Chief Operating Officer | 05/15/2020 | 1,176 |
| Hearne Michael S | Chief Financial Officer | 04/30/2020 | 1,125 |
| O'Connell Joseph P | Chief Medical Officer | 04/30/2020 | 933 |
| Lemkey John G | Chief Operating Officer | 04/30/2020 | 1,173 |
| Hearne Michael S | Chief Financial Officer | 04/15/2020 | 1,141 |
| O'Connell Joseph P | Chief Medical Officer | 04/15/2020 | 936 |
| Lemkey John G | Chief Operating Officer | 04/15/2020 | 1,164 |
| Hearne Michael S | Chief Financial Officer | 03/31/2020 | 563 |
| O'Connell Joseph P | Chief Medical Officer | 03/31/2020 | 939 |
| Lemkey John G | Chief Operating Officer | 03/31/2020 | 1,173 |
| Hearne Michael S | Chief Financial Officer | 03/13/2020 | 568 |
| O'Connell Joseph P | Chief Medical Officer | 03/13/2020 | 940 |
| Lemkey John G | Chief Operating Officer | 03/13/2020 | 1,175 |
| Hearne Michael S | Chief Financial Officer | 02/28/2020 | 553 |
| O'Connell Joseph P | Chief Medical Officer | 02/28/2020 | 931 |
| Lemkey John G | Chief Operating Officer | 02/28/2020 | 1,182 |
| Hearne Michael S | Chief Financial Officer | 02/14/2020 | 561 |
| O'Connell Joseph P | Chief Medical Officer | 02/14/2020 | 936 |
| Lemkey John G | Chief Operating Officer | 02/14/2020 | 1,149 |
| Hearne Michael S | Chief Financial Officer | 01/31/2020 | 571 |
| O'Connell Joseph P | Chief Medical Officer | 01/31/2020 | 943 |
| Lemkey John G | Chief Operating Officer | 01/31/2020 | 1,191 |
| Hearne Michael S | Chief Financial Officer | 01/15/2020 | 556 |
| O'Connell Joseph P | Chief Medical Officer | 01/15/2020 | 926 |
| Lemkey John G | Chief Operating Officer | 01/15/2020 | 1,157 |
| Hearne Michael S | Chief Financial Officer | 12/31/2019 | 552 |
| O'Connell Joseph P | Chief Medical Officer | 12/31/2019 | 910 |
| Lemkey John G | Chief Operating Officer | 12/31/2019 | 1,131 |
| Hearne Michael S | Chief Financial Officer | 12/13/2019 | 542 |
| O'Connell Joseph P | Chief Medical Officer | 12/13/2019 | 911 |
| Lemkey John G | Chief Operating Officer | 12/13/2019 | 1,157 |
| Hearne Michael S | Chief Financial Officer | 11/29/2019 | 555 |
| O'Connell Joseph P | Chief Medical Officer | 11/29/2019 | 906 |
| Lemkey John G | Chief Operating Officer | 11/29/2019 | 1,140 |
| Hearne Michael S | Chief Financial Officer | 11/15/2019 | 535 |
| O'Connell Joseph P | Chief Medical Officer | 11/15/2019 | 929 |
| Lemkey John G | Chief Operating Officer | 11/15/2019 | 1,126 |
| Hearne Michael S | Chief Financial Officer | 10/31/2019 | 567 |
| O'Connell Joseph P | Chief Medical Officer | 10/31/2019 | 891 |
| Lemkey John G | Chief Operating Officer | 10/31/2019 | 1,134 |
| Hearne Michael S | Chief Financial Officer | 10/15/2019 | 533 |
| O'Connell Joseph P | Chief Medical Officer | 10/15/2019 | 921 |
| Lemkey John G | Chief Operating Officer | 10/15/2019 | 1,139 |
| Hearne Michael S | Chief Financial Officer | 09/30/2019 | 553 |
| O'Connell Joseph P | Chief Medical Officer | 09/30/2019 | 907 |
| Lemkey John G | Chief Operating Officer | 09/30/2019 | 1,129 |
| Hearne Michael S | Chief Financial Officer | 09/13/2019 | 555 |
| O'Connell Joseph P | Chief Medical Officer | 09/13/2019 | 916 |
| Lemkey John G | Chief Operating Officer | 09/13/2019 | 1,157 |
| Hearne Michael S | Chief Financial Officer | 08/30/2019 | 550 |
| O'Connell Joseph P | Chief Medical Officer | 08/30/2019 | 890 |
| Lemkey John G | Chief Operating Officer | 08/30/2019 | 1,126 |
| Hearne Michael S | Chief Financial Officer | 08/15/2019 | 540 |
| O'Connell Joseph P | Chief Medical Officer | 08/15/2019 | 938 |
| Lemkey John G | Chief Operating Officer | 08/15/2019 | 1,137 |
| Hearne Michael S | Chief Financial Officer | 07/31/2019 | 554 |
| O'Connell Joseph P | Chief Medical Officer | 07/31/2019 | 901 |
| Lemkey John G | Chief Operating Officer | 07/31/2019 | 1,143 |
| Hearne Michael S | Chief Financial Officer | 07/15/2019 | 538 |
| O'Connell Joseph P | Chief Medical Officer | 07/15/2019 | 897 |
| Lemkey John G | Chief Operating Officer | 07/15/2019 | 1,136 |
| Hearne Michael S | Chief Financial Officer | 06/28/2019 | 530 |
| O'Connell Joseph P | Chief Medical Officer | 06/28/2019 | 905 |
| Lemkey John G | Chief Operating Officer | 06/28/2019 | 1,123 |
| Boxer Capital, LLC | 10% Owner | 06/26/2019 | 9,999,990 |
| Vacirca Jeff L | Director | 06/26/2019 | 500,006 |
| TANG KEVIN C | Chief Executive Officer | 06/26/2019 | 20,000,006 |
| TANG KEVIN C | Chief Executive Officer | 06/17/2019 | 269,231 |
| TANG KEVIN C | Chief Executive Officer | 06/14/2019 | 464,294 |
| TANG KEVIN C | Chief Executive Officer | 06/18/2019 | 574,020 |
| Hearne Michael S | Chief Financial Officer | 06/14/2019 | 553 |
| O'Connell Joseph P | Chief Medical Officer | 06/14/2019 | 914 |
| Lemkey John G | Chief Operating Officer | 06/14/2019 | 1,148 |
| TANG KEVIN C | Chief Executive Officer | 06/07/2019 | 526,220 |
| TANG KEVIN C | Chief Executive Officer | 06/06/2019 | 1,561,237 |
| TANG KEVIN C | Chief Executive Officer | 06/05/2019 | 1,020,541 |
| TANG KEVIN C | Chief Executive Officer | 06/04/2019 | 970,772 |
| TANG KEVIN C | Chief Executive Officer | 06/03/2019 | 343,904 |
| Hearne Michael S | Chief Financial Officer | 05/31/2019 | 548 |
| O'Connell Joseph P | Chief Medical Officer | 05/31/2019 | 914 |
| Lemkey John G | Chief Operating Officer | 05/31/2019 | 1,133 |
| Hearne Michael S | Chief Financial Officer | 05/15/2019 | 547 |
| O'Connell Joseph P | Chief Medical Officer | 05/15/2019 | 906 |
| Lemkey John G | Chief Operating Officer | 05/15/2019 | 1,132 |
| Hearne Michael S | Chief Financial Officer | 04/30/2019 | 551 |
| O'Connell Joseph P | Chief Medical Officer | 04/30/2019 | 919 |
| Lemkey John G | Chief Operating Officer | 04/30/2019 | 1,153 |
| Hearne Michael S | Chief Financial Officer | 04/15/2019 | 552 |
| O'Connell Joseph P | Chief Medical Officer | 04/15/2019 | 913 |
| Lemkey John G | Chief Operating Officer | 04/15/2019 | 1,126 |
| Lemkey John G | Chief Operating Officer | 03/29/2019 | 1,146 |
| Hearne Michael S | Chief Financial Officer | 03/29/2019 | 545 |
| O'Connell Joseph P | Chief Medical Officer | 03/29/2019 | 902 |
| O'Connell Joseph P | Chief Medical Officer | 03/15/2019 | 909 |
| Hearne Michael S | Chief Financial Officer | 03/15/2019 | 545 |
| Lemkey John G | Chief Operating Officer | 03/15/2019 | 1,131 |
| TANG KEVIN C | Chief Executive Officer | 03/08/2019 | 1,874,583 |
| TANG KEVIN C | Chief Executive Officer | 03/07/2019 | 681,733 |
| Vacirca Jeff L | Director | 03/04/2019 | 51,000 |
| O'Connell Joseph P | Chief Medical Officer | 02/28/2019 | 911 |
| Lemkey John G | Chief Operating Officer | 02/28/2019 | 1,135 |
| Hearne Michael S | Chief Financial Officer | 02/28/2019 | 546 |
| Hearne Michael S | Chief Financial Officer | 02/15/2019 | 548 |
| O'Connell Joseph P | Chief Medical Officer | 02/15/2019 | 913 |
| Lemkey John G | Chief Operating Officer | 02/15/2019 | 1,137 |
| Hearne Michael S | Chief Financial Officer | 01/31/2019 | 535 |
| O'Connell Joseph P | Chief Medical Officer | 01/31/2019 | 901 |
| Lemkey John G | Chief Operating Officer | 01/31/2019 | 1,140 |
| Hearne Michael S | Chief Financial Officer | 01/15/2019 | 554 |
| O'Connell Joseph P | Chief Medical Officer | 01/15/2019 | 914 |
| Lemkey John G | Chief Operating Officer | 01/15/2019 | 1,136 |
| Hearne Michael S | Chief Financial Officer | 12/31/2018 | 539 |
| O'Connell Joseph P | Chief Medical Officer | 12/31/2018 | 886 |
| Lemkey John G | Chief Operating Officer | 12/31/2018 | 838 |
| TANG KEVIN C | Chief Executive Officer | 12/31/2018 | 460,929 |
| TANG KEVIN C | Chief Executive Officer | 12/28/2018 | 253,863 |
| TANG KEVIN C | Chief Executive Officer | 12/27/2018 | 120,315 |
| Davis Aaron I. | Director | 12/21/2018 | 1,347,015 |
| Davis Aaron I. | Director | 12/26/2018 | 311,815 |
| Boxer Capital, LLC | Director | 12/26/2018 | 311,815 |
| Boxer Capital, LLC | Director | 12/21/2018 | 1,347,015 |
| TANG KEVIN C | Chief Executive Officer | 12/26/2018 | 368,287 |
| TANG KEVIN C | Chief Executive Officer | 12/21/2018 | 255,828 |
| TANG KEVIN C | Chief Executive Officer | 12/20/2018 | 131,742 |
| Hearne Michael S | Chief Financial Officer | 12/14/2018 | 540 |
| O'Connell Joseph P | Chief Medical Officer | 12/14/2018 | 874 |
| Lemkey John G | Chief Operating Officer | 12/14/2018 | 822 |
| TANG KEVIN C | Chief Executive Officer | 12/18/2018 | 167,189 |
| TANG KEVIN C | Chief Executive Officer | 12/17/2018 | 268,612 |
| TANG KEVIN C | Chief Executive Officer | 12/14/2018 | 150,838 |
| TANG KEVIN C | Chief Executive Officer | 12/12/2018 | 228,946 |
| TANG KEVIN C | Chief Executive Officer | 12/11/2018 | 83,128 |
| TANG KEVIN C | Chief Executive Officer | 12/06/2018 | 153,573 |
| TANG KEVIN C | Chief Executive Officer | 12/07/2018 | 142,291 |
| Hearne Michael S | Chief Financial Officer | 11/30/2018 | 536 |
| O'Connell Joseph P | Chief Medical Officer | 11/30/2018 | 884 |
| Lemkey John G | Chief Operating Officer | 11/30/2018 | 844 |
| TANG KEVIN C | Chief Executive Officer | 11/27/2018 | 47,912 |
| TANG KEVIN C | Chief Executive Officer | 11/23/2018 | 70,830 |
| TANG KEVIN C | Chief Executive Officer | 11/21/2018 | 81,141 |
| TANG KEVIN C | Chief Executive Officer | 11/26/2018 | 107,046 |
| O'Connell Joseph P | Chief Medical Officer | 11/15/2018 | 885 |
| Lemkey John G | Chief Financial Officer | 11/15/2018 | 828 |
| TANG KEVIN C | Chief Executive Officer | 11/01/2018 | 148,727 |
| O'Connell Joseph P | Chief Medical Officer | 10/31/2018 | 888 |
| Lemkey John G | Chief Financial Officer | 10/31/2018 | 826 |
| TANG KEVIN C | Chief Executive Officer | 10/29/2018 | 149,642 |
| TANG KEVIN C | Chief Executive Officer | 10/26/2018 | 3,725 |
| Davis Aaron I. | Director | 10/24/2018 | 394,753 |
| Boxer Capital, LLC | Director | 10/24/2018 | 394,753 |
| TANG KEVIN C | Chief Executive Officer | 10/25/2018 | 154,059 |
| TANG KEVIN C | Chief Executive Officer | 10/24/2018 | 198,632 |
| TANG KEVIN C | Chief Executive Officer | 10/23/2018 | 257,609 |
| O'Connell Joseph P | Chief Medical Officer | 10/15/2018 | 876 |
| Lemkey John G | Chief Financial Officer | 10/15/2018 | 834 |
| O'Connell Joseph P | Chief Medical Officer | 09/28/2018 | 297 |
| Lemkey John G | Chief Financial Officer | 09/28/2018 | 842 |
| TANG KEVIN C | Chief Executive Officer | 09/28/2018 | 650,378 |
| TANG KEVIN C | Chief Executive Officer | 09/27/2018 | 115,929 |
| TANG KEVIN C | Chief Executive Officer | 09/26/2018 | 190,664 |
| TANG KEVIN C | Chief Executive Officer | 09/25/2018 | 196,477 |
| TANG KEVIN C | Chief Executive Officer | 09/24/2018 | 402,832 |
| TANG KEVIN C | Chief Executive Officer | 09/20/2018 | 562,736 |
| TANG KEVIN C | Chief Executive Officer | 09/19/2018 | 232,374 |
| TANG KEVIN C | Chief Executive Officer | 09/18/2018 | 964,186 |
| O'Connell Joseph P | Chief Medical Officer | 09/14/2018 | 293 |
| Lemkey John G | Chief Financial Officer | 09/14/2018 | 829 |
| O'Connell Joseph P | Chief Medical Officer | 08/31/2018 | 294 |
| Lemkey John G | Chief Financial Officer | 08/31/2018 | 832 |
| TANG KEVIN C | Chief Executive Officer | 08/21/2018 | 146,151 |
| TANG KEVIN C | Chief Executive Officer | 08/16/2018 | 730,681 |
| TANG KEVIN C | Chief Executive Officer | 08/20/2018 | 191,613 |
| TANG KEVIN C | Chief Executive Officer | 08/17/2018 | 45,980 |
| O'Connell Joseph P | Chief Medical Officer | 08/15/2018 | 303 |
| Lemkey John G | Chief Financial Officer | 08/15/2018 | 844 |
| TANG KEVIN C | Chief Executive Officer | 08/15/2018 | 179,242 |
| TANG KEVIN C | Chief Executive Officer | 08/14/2018 | 125,352 |
| TANG KEVIN C | Chief Executive Officer | 08/13/2018 | 127,111 |
| O'Connell Joseph P | Chief Medical Officer | 07/31/2018 | 286 |
| Lemkey John G | Chief Financial Officer | 07/31/2018 | 823 |
| O'Connell Joseph P | Chief Medical Officer | 07/13/2018 | 305 |
| Lemkey John G | Chief Financial Officer | 07/13/2018 | 835 |
| O'Connell Joseph P | Chief Medical Officer | 06/29/2018 | 300 |
| Lemkey John G | Chief Financial Officer | 06/29/2018 | 845 |
| O'Connell Joseph P | Chief Medical Officer | 06/15/2018 | 293 |
| Lemkey John G | Chief Financial Officer | 06/15/2018 | 834 |
| O'Connell Joseph P | Chief Medical Officer | 05/31/2018 | 285 |
| Lemkey John G | Chief Financial Officer | 05/31/2018 | 816 |
| O'Connell Joseph P | Chief Medical Officer | 05/15/2018 | 295 |
| Lemkey John G | Chief Financial Officer | 05/15/2018 | 847 |
| O'Connell Joseph P | Chief Medical Officer | 04/30/2018 | 305 |
| Lemkey John G | Chief Financial Officer | 04/30/2018 | 824 |
| O'Connell Joseph P | Chief Medical Officer | 04/13/2018 | 276 |
| Lemkey John G | Chief Financial Officer | 04/13/2018 | 828 |
| Boxer Capital, LLC | Director | 03/26/2018 | 754,096 |
| Boxer Capital, LLC | Director | 03/23/2018 | 1,028,914 |
| Boxer Capital, LLC | Director | 03/22/2018 | 490,143 |
| Davis Aaron I. | Director | 03/23/2018 | 1,028,914 |
| Davis Aaron I. | Director | 03/22/2018 | 490,143 |
| Davis Aaron I. | Director | 03/26/2018 | 754,096 |
| TANG KEVIN C | Chief Executive Officer | 03/01/2018 | 121,499 |
| TANG KEVIN C | Chief Executive Officer | 02/28/2018 | 263,683 |
| TANG KEVIN C | Chief Executive Officer | 02/23/2018 | 60,887 |
| TANG KEVIN C | Chief Executive Officer | 02/27/2018 | 341,285 |
| TANG KEVIN C | Chief Executive Officer | 02/26/2018 | 382,467 |
| TANG KEVIN C | Chief Executive Officer | 02/22/2018 | 478,065 |
| TANG KEVIN C | Chief Executive Officer | 02/21/2018 | 374,660 |
| TANG KEVIN C | Chief Executive Officer | 02/20/2018 | 209,086 |
| TANG KEVIN C | Chief Executive Officer | 02/16/2018 | 1,380,447 |
| TANG KEVIN C | Chief Executive Officer | 02/15/2018 | 768,075 |
| TANG KEVIN C | Chief Executive Officer | 02/14/2018 | 732,822 |
| Vacirca Jeff L | Director | 12/12/2017 | 23,300 |
| Davis Aaron I. | Director | 12/06/2017 | 9,999,984 |
| Boxer Capital, LLC | Director | 12/06/2017 | 9,999,984 |
| TANG KEVIN C | Chief Executive Officer | 12/07/2017 | 30,999,984 |
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