Neurocrine Biosciences, Inc.. (NBIX) NASDAQ
$136.39 (2.58) (-1.86%)
Market Cap: $13.83B
As of 04/25/24 03:08 PM EDT. Market open.
Neurocrine Biosciences, Inc.. (NBIX)
NASDAQ
$136.39
(2.58) (-1.86%)
Market Cap: $13.83B
As of 04/25/24 03:08 PM EDT. Market open.
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neurocrine biosciences, inc of san diego is a product based biopharmaceutical company focusing on the development and commercialization of innovative pharmaceutical products to treat unmet medical needs. the company's research and development efforts are focused on neurological and endocrine diseases and disorders. our product candidates address some of the largest pharmaceutical markets in the ... read more
COMPANY PROFILE
Sector
Industry
CEO
Kevin Gorman
Full Time Employees
1,252
CEO Compensation (Base)
$675,000
CEO Compensation (Total)
$8.63M
Sector
Industry
CEO
Kevin Gorman
Full Time Employees
1,252
CEO Compensation (Base)
$675,000
CEO Compensation (Total)
$8.63M
Address
12780 El Camino Real, California, San Diego, 92130-2042.
PRICE CHART FOR NEUROCRINE BIOSCIENCES, INC.
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NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
$138.80
Previous Close
$138.97
Days Range
$138.01 - $144.52
52 week range
$89.04 - $148.37
Volume
377,301
Avg. Volume (30 days)
814,152
Market Cap
$13.83B
Dividend Yield
-
P/E
55.38
Shares Outstanding
99,507,000
Open
$138.80
Previous Close
$138.97
Days Range
$138.01 - $144.52
52 week range
$89.04 - $148.37
Volume
377,301
Avg. Volume (30 days)
814,152
Market Cap
$13.83B
Dividend Yield
-
P/E
55.38
Shares Outstanding
99,507,000
FINANCIAL STATEMENTS FOR NEUROCRINE BIOSCIENCES, INC.
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INSIDER TRANSACTIONS FOR NEUROCRINE BIOSCIENCES, INC.
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| BENEVICH ERIC | Chief Commercial Officer | Apr 15, 2024 | Option Exercise | $81.21 | 19,818 | 1,609,431 | 53,365 | Apr 17, 2024, 05:19 PM |
| BENEVICH ERIC | Chief Commercial Officer | Apr 15, 2024 | Sale | $133.36 | 19,818 | 2,643,020 | 40,778 | Apr 17, 2024, 05:19 PM |
| Delaet Ingrid | Chief Regulatory Officer | Mar 21, 2024 | Option Exercise | $103.52 | 5,000 | 517,600 | 12,507 | Mar 25, 2024, 06:02 PM |
| Delaet Ingrid | Chief Regulatory Officer | Mar 21, 2024 | Sale | $145.06 | 5,000 | 725,320 | 7,507 | Mar 25, 2024, 06:02 PM |
| BENEVICH ERIC | Chief Commercial Officer | Mar 14, 2024 | Option Exercise | $80.90 | 75,000 | 6,067,628 | 110,299 | Mar 15, 2024, 05:33 PM |
| BENEVICH ERIC | Chief Commercial Officer | Mar 14, 2024 | Sale | $139.38 | 75,000 | 10,453,418 | 40,778 | Mar 15, 2024, 05:33 PM |
| MORROW GEORGE J | Director | Mar 14, 2024 | Option Exercise | $39.79 | 40,000 | 1,591,600 | 20,000 | Mar 15, 2024, 05:25 PM |
| MORROW GEORGE J | Director | Mar 14, 2024 | Sale | $139.42 | 40,000 | 5,576,710 | 0 | Mar 15, 2024, 05:25 PM |
| POPS RICHARD F | Director | Mar 13, 2024 | Option Exercise | $42.76 | 23,200 | 992,032 | 52,712 | Mar 15, 2024, 05:19 PM |
| POPS RICHARD F | Director | Mar 13, 2024 | Sale | $140.33 | 23,200 | 3,255,621 | 29,512 | Mar 15, 2024, 05:19 PM |
| Delaet Ingrid | Chief Regulatory Officer | Mar 13, 2024 | Option Exercise | $106.02 | 3,000 | 318,060 | 10,507 | Mar 15, 2024, 05:15 PM |
| Delaet Ingrid | Chief Regulatory Officer | Mar 13, 2024 | Sale | $140.14 | 3,000 | 420,419 | 7,507 | Mar 15, 2024, 05:15 PM |
| POPS RICHARD F | Director | Mar 08, 2024 | Option Exercise | $42.76 | 1,700 | 72,692 | 31,212 | Mar 12, 2024, 06:47 PM |
| POPS RICHARD F | Director | Mar 11, 2024 | Option Exercise | $42.76 | 100 | 4,276 | 29,612 | Mar 12, 2024, 06:47 PM |
| POPS RICHARD F | Director | Mar 08, 2024 | Sale | $140.05 | 1,700 | 238,078 | 29,512 | Mar 12, 2024, 06:47 PM |
| POPS RICHARD F | Director | Mar 11, 2024 | Sale | $140.00 | 100 | 14,000 | 29,512 | Mar 12, 2024, 06:47 PM |
| Delaet Ingrid | Chief Regulatory Officer | Mar 11, 2024 | Option Exercise | $106.02 | 200 | 21,204 | 7,707 | Mar 12, 2024, 06:38 PM |
| Delaet Ingrid | Chief Regulatory Officer | Mar 08, 2024 | Option Exercise | $106.02 | 1,800 | 190,836 | 9,307 | Mar 12, 2024, 06:38 PM |
| Delaet Ingrid | Chief Regulatory Officer | Mar 11, 2024 | Sale | $140.00 | 200 | 28,000 | 7,507 | Mar 12, 2024, 06:38 PM |
| Delaet Ingrid | Chief Regulatory Officer | Mar 08, 2024 | Sale | $140.03 | 1,800 | 252,053 | 7,507 | Mar 12, 2024, 06:38 PM |
| Delaet Ingrid | Chief Regulatory Officer | Feb 29, 2024 | Option Exercise | $79.02 | 273 | 21,572 | 7,780 | Feb 29, 2024, 07:02 PM |
| Delaet Ingrid | Chief Regulatory Officer | Feb 28, 2024 | Option Exercise | $79.02 | 6,544 | 517,107 | 10,007 | Feb 29, 2024, 07:02 PM |
| Delaet Ingrid | Chief Regulatory Officer | Feb 28, 2024 | Sale | $135.34 | 6,544 | 885,637 | 7,507 | Feb 29, 2024, 07:02 PM |
| Delaet Ingrid | Chief Regulatory Officer | Feb 29, 2024 | Sale | $135.51 | 273 | 36,994 | 7,507 | Feb 29, 2024, 07:02 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 28, 2024 | Option Exercise | $53.67 | 75,000 | 4,025,043 | 93,759 | Feb 29, 2024, 06:55 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 28, 2024 | Sale | $134.69 | 75,000 | 10,101,607 | 40,616 | Feb 29, 2024, 06:55 PM |
| Norwalk Leslie V | Director | Feb 27, 2024 | Option Exercise | $84.95 | 8,000 | 679,600 | 8,000 | Feb 29, 2024, 06:50 PM |
| Norwalk Leslie V | Director | Feb 27, 2024 | Sale | $135.67 | 8,000 | 1,085,388 | 0 | Feb 29, 2024, 06:50 PM |
| POPS RICHARD F | Director | Feb 20, 2024 | Option Exercise | $12.98 | 15,000 | 194,700 | 44,512 | Feb 22, 2024, 05:11 PM |
| POPS RICHARD F | Director | Feb 20, 2024 | Sale | $132.47 | 15,000 | 1,987,047 | 29,512 | Feb 22, 2024, 05:11 PM |
| ROBERTS EIRY | Chief Medical Officer | Feb 13, 2024 | Sale | $132.96 | 1,114 | 148,122 | 23,716 | Feb 15, 2024, 05:51 PM |
| Onyia Jude | Chief Scientific Officer | Feb 13, 2024 | Sale | $132.94 | 1,432 | 190,371 | 13,128 | Feb 15, 2024, 05:48 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 13, 2024 | Sale | $132.99 | 1,098 | 146,028 | 39,740 | Feb 15, 2024, 05:45 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 13, 2024 | Sale | $133.02 | 2,832 | 376,700 | 514,596 | Feb 15, 2024, 05:43 PM |
| Gano Kyle | Chief Business Development Off | Feb 13, 2024 | Sale | $132.89 | 1,352 | 179,674 | 135,166 | Feb 15, 2024, 05:40 PM |
| Delaet Ingrid | Chief Regulatory Officer | Feb 13, 2024 | Sale | $133.03 | 716 | 95,253 | 7,507 | Feb 15, 2024, 05:38 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 13, 2024 | Sale | $133.04 | 796 | 105,902 | 17,976 | Feb 15, 2024, 05:35 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Feb 13, 2024 | Sale | $133.07 | 1,811 | 240,996 | 5,751 | Feb 15, 2024, 05:33 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 13, 2024 | Sale | $133.01 | 1,098 | 146,050 | 40,616 | Feb 15, 2024, 05:29 PM |
| ABERNETHY MATT | Chief Financial Officer | Feb 13, 2024 | Sale | $132.85 | 1,352 | 179,612 | 31,528 | Feb 15, 2024, 05:27 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 13, 2024 | Option Exercise | $39.28 | 5,090 | 199,951 | 512,052 | Feb 14, 2024, 05:17 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Feb 08, 2024 | Sale | $135.41 | 1,328 | 179,830 | 5,523 | Feb 08, 2024, 07:46 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Feb 06, 2024 | Sale | $141.96 | 456 | 64,734 | 5,110 | Feb 08, 2024, 07:46 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 08, 2024 | Sale | $135.44 | 1,329 | 179,995 | 17,892 | Feb 08, 2024, 07:35 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 06, 2024 | Sale | $142.07 | 1,215 | 172,617 | 17,838 | Feb 08, 2024, 07:35 PM |
| ROBERTS EIRY | Chief Medical Officer | Feb 08, 2024 | Sale | $134.21 | 980 | 131,522 | 22,717 | Feb 08, 2024, 07:28 PM |
| ROBERTS EIRY | Chief Medical Officer | Feb 06, 2024 | Sale | $142.24 | 1,121 | 159,446 | 21,837 | Feb 08, 2024, 07:28 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 08, 2024 | Sale | $134.24 | 911 | 122,289 | 38,755 | Feb 08, 2024, 07:25 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 06, 2024 | Sale | $142.17 | 1,041 | 147,995 | 37,939 | Feb 08, 2024, 07:25 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 08, 2024 | Sale | $134.15 | 2,274 | 305,052 | 506,962 | Feb 08, 2024, 07:21 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 06, 2024 | Sale | $142.18 | 3,040 | 432,218 | 504,919 | Feb 08, 2024, 07:21 PM |
| Gano Kyle | Chief Business Development Off | Feb 08, 2024 | Sale | $134.20 | 980 | 131,519 | 133,952 | Feb 08, 2024, 07:17 PM |
| Gano Kyle | Chief Business Development Off | Feb 06, 2024 | Sale | $142.20 | 1,600 | 227,522 | 133,072 | Feb 08, 2024, 07:17 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 06, 2024 | Sale | $142.12 | 1,280 | 181,910 | 38,751 | Feb 08, 2024, 07:15 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 08, 2024 | Sale | $134.19 | 980 | 131,509 | 39,631 | Feb 08, 2024, 07:15 PM |
| ABERNETHY MATT | Chief Financial Officer | Feb 08, 2024 | Sale | $134.21 | 980 | 131,529 | 30,314 | Feb 08, 2024, 07:12 PM |
| ABERNETHY MATT | Chief Financial Officer | Feb 06, 2024 | Sale | $142.19 | 1,280 | 182,000 | 29,434 | Feb 08, 2024, 07:12 PM |
| ROBERTS EIRY | Chief Medical Officer | Jan 31, 2024 | Sale | $140.79 | 1,457 | 205,132 | 20,832 | Feb 02, 2024, 07:29 PM |
| Onyia Jude | Chief Scientific Officer | Jan 31, 2024 | Sale | $141.94 | 126 | 17,884 | 11,843 | Feb 02, 2024, 07:26 PM |
| Lippoldt Darin | Chief Legal Officer | Jan 31, 2024 | Sale | $140.65 | 1,250 | 175,810 | 37,005 | Feb 02, 2024, 07:24 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 31, 2024 | Sale | $140.69 | 2,707 | 380,845 | 502,188 | Feb 02, 2024, 07:21 PM |
| Gano Kyle | Chief Business Development Off | Jan 31, 2024 | Sale | $140.70 | 1,541 | 216,813 | 131,635 | Feb 02, 2024, 07:17 PM |
| Delaet Ingrid | Chief Regulatory Officer | Feb 01, 2024 | Sale | $139.77 | 623 | 87,077 | 6,865 | Feb 02, 2024, 07:14 PM |
| Delaet Ingrid | Chief Regulatory Officer | Jan 31, 2024 | Sale | $141.94 | 422 | 59,899 | 6,309 | Feb 02, 2024, 07:14 PM |
| Cooke Julie | Chief Human Resources Officer | Jan 31, 2024 | Sale | $141.29 | 1,740 | 245,842 | 18,087 | Feb 02, 2024, 07:11 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Jan 31, 2024 | Sale | $140.80 | 2,096 | 295,115 | 5,886 | Feb 02, 2024, 07:07 PM |
| BENEVICH ERIC | Chief Commercial Officer | Jan 31, 2024 | Sale | $140.78 | 1,207 | 169,927 | 37,601 | Feb 02, 2024, 07:05 PM |
| ABERNETHY MATT | Chief Financial Officer | Jan 31, 2024 | Sale | $140.72 | 1,283 | 180,539 | 28,284 | Feb 02, 2024, 07:00 PM |
| Lippoldt Darin | Chief Legal Officer | Jan 22, 2024 | Option Exercise | $79.02 | 10,000 | 790,200 | 45,882 | Jan 24, 2024, 05:47 PM |
| Lippoldt Darin | Chief Legal Officer | Jan 22, 2024 | Sale | $139.86 | 10,000 | 1,398,553 | 35,882 | Jan 24, 2024, 05:47 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 08, 2024 | Option Exercise | $19.59 | 105,835 | 2,073,308 | 605,589 | Jan 10, 2024, 04:31 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 09, 2024 | Option Exercise | $19.59 | 62,023 | 1,215,031 | 561,777 | Jan 10, 2024, 04:31 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 09, 2024 | Sale | $134.01 | 62,023 | 8,311,895 | 499,754 | Jan 10, 2024, 04:31 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 08, 2024 | Sale | $132.44 | 105,835 | 14,016,523 | 499,754 | Jan 10, 2024, 04:31 PM |
| Gano Kyle | Chief Business Development Off | Jan 02, 2024 | Option Exercise | $19.59 | 75,000 | 1,469,250 | 199,134 | Jan 04, 2024, 06:32 PM |
| Gano Kyle | Chief Business Development Off | Jan 02, 2024 | Sale | $131.47 | 75,000 | 9,860,195 | 130,250 | Jan 04, 2024, 06:32 PM |
| RASTETTER WILLIAM H | Director | Jan 02, 2024 | Option Exercise | $12.98 | 20,000 | 259,600 | 62,785 | Jan 04, 2024, 06:26 PM |
| RASTETTER WILLIAM H | Director | Jan 02, 2024 | Sale | $131.47 | 11,044 | 1,451,927 | 51,741 | Jan 04, 2024, 06:26 PM |
| ROBERTS EIRY | Chief Medical Officer | Dec 22, 2023 | Sale | $126.74 | 10,000 | 1,267,448 | 19,521 | Dec 27, 2023, 04:15 PM |
| LYONS GARY A | Director | Dec 22, 2023 | Sale | $130.04 | 10,000 | 1,300,443 | 193,697 | Dec 27, 2023, 04:10 PM |
| Cooke Julie | Chief Human Resources Officer | Dec 22, 2023 | Option Exercise | $73.04 | 24,000 | 1,752,900 | 31,263 | Dec 27, 2023, 04:08 PM |
| Cooke Julie | Chief Human Resources Officer | Dec 22, 2023 | Sale | $128.66 | 24,000 | 3,087,808 | 17,263 | Dec 27, 2023, 04:08 PM |
| ROBERTS EIRY | Chief Medical Officer | Dec 12, 2023 | Option Exercise | $81.05 | 13,925 | 1,128,621 | 36,499 | Dec 14, 2023, 05:22 PM |
| ROBERTS EIRY | Chief Medical Officer | Dec 12, 2023 | Sale | $120.30 | 13,925 | 1,675,240 | 29,521 | Dec 14, 2023, 05:22 PM |
| ROBERTS EIRY | Chief Medical Officer | Dec 07, 2023 | Option Exercise | $78.52 | 77,379 | 6,076,120 | 68,243 | Dec 11, 2023, 06:18 PM |
| ROBERTS EIRY | Chief Medical Officer | Dec 08, 2023 | Option Exercise | $81.05 | 300 | 24,315 | 29,721 | Dec 11, 2023, 06:18 PM |
| ROBERTS EIRY | Chief Medical Officer | Dec 07, 2023 | Sale | $120.37 | 77,379 | 9,314,319 | 29,521 | Dec 11, 2023, 06:18 PM |
| ROBERTS EIRY | Chief Medical Officer | Dec 08, 2023 | Sale | $120.10 | 300 | 36,031 | 29,521 | Dec 11, 2023, 06:18 PM |
| ROBERTS EIRY | Chief Medical Officer | Dec 06, 2023 | Option Exercise | $77.81 | 8,396 | 653,293 | 37,917 | Dec 08, 2023, 07:09 PM |
| ROBERTS EIRY | Chief Medical Officer | Dec 06, 2023 | Sale | $120.03 | 8,396 | 1,007,780 | 29,521 | Dec 08, 2023, 07:09 PM |
| Lippoldt Darin | Chief Legal Officer | Dec 06, 2023 | Option Exercise | $43.24 | 20,830 | 900,689 | 56,712 | Dec 08, 2023, 06:23 PM |
| Lippoldt Darin | Chief Legal Officer | Dec 06, 2023 | Sale | $119.86 | 20,830 | 2,496,648 | 35,882 | Dec 08, 2023, 06:23 PM |
| LYONS GARY A | Director | Dec 01, 2023 | Option Exercise | $12.98 | 5,000 | 64,900 | 208,697 | Dec 05, 2023, 04:54 PM |
| LYONS GARY A | Director | Dec 01, 2023 | Sale | $116.77 | 5,000 | 583,837 | 203,697 | Dec 05, 2023, 04:54 PM |
| Onyia Jude | Chief Scientific Officer | Nov 29, 2023 | Sale | $113.57 | 2,331 | 264,733 | 11,732 | Dec 01, 2023, 05:41 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 27, 2023 | Sale | $112.27 | 10,919 | 1,225,911 | 35,882 | Nov 29, 2023, 04:36 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Oct 02, 2023 | Sale | $112.68 | 1,437 | 161,921 | 4,894 | Oct 04, 2023, 05:07 PM |
| LYONS GARY A | Director | Sep 12, 2023 | Option Exercise | $12.98 | 5,000 | 64,900 | 208,697 | Sep 14, 2023, 04:51 PM |
| LYONS GARY A | Director | Sep 12, 2023 | Sale | $115.02 | 5,000 | 575,120 | 203,697 | Sep 14, 2023, 04:51 PM |
| LYONS GARY A | Director | Sep 01, 2023 | Option Exercise | $12.98 | 5,000 | 64,900 | 208,697 | Sep 06, 2023, 04:25 PM |
| LYONS GARY A | Director | Sep 01, 2023 | Sale | $110.06 | 5,000 | 550,316 | 203,697 | Sep 06, 2023, 04:25 PM |
| Cooke Julie | Chief Human Resources Officer | Sep 01, 2023 | Sale | $110.93 | 824 | 91,406 | 17,263 | Sep 06, 2023, 04:22 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Aug 30, 2023 | Sale | $107.60 | 2,733 | 294,058 | 4,898 | Sep 01, 2023, 04:36 PM |
| Delaet Ingrid | Chief Regulatory Officer | Aug 28, 2023 | Sale | $107.52 | 1,431 | 153,861 | 5,931 | Aug 30, 2023, 04:38 PM |
| ROBERTS EIRY | Chief Medical Officer | Aug 21, 2023 | Sale | $107.38 | 3,198 | 343,388 | 29,521 | Aug 23, 2023, 08:20 PM |
| Onyia Jude | Chief Scientific Officer | Aug 21, 2023 | Sale | $107.37 | 3,198 | 343,368 | 9,638 | Aug 23, 2023, 08:10 PM |
| Lippoldt Darin | Chief Legal Officer | Aug 21, 2023 | Sale | $107.39 | 2,132 | 228,951 | 46,991 | Aug 23, 2023, 08:09 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Aug 21, 2023 | Sale | $107.40 | 9,328 | 1,001,816 | 499,754 | Aug 23, 2023, 08:08 PM |
| Gano Kyle | Chief Business Development Off | Aug 21, 2023 | Sale | $107.41 | 2,132 | 228,993 | 130,250 | Aug 23, 2023, 08:05 PM |
| Delaet Ingrid | Chief Regulatory Officer | Aug 21, 2023 | Sale | $107.42 | 1,404 | 150,820 | 4,645 | Aug 23, 2023, 08:04 PM |
| Cooke Julie | Chief Human Resources Officer | Aug 21, 2023 | Sale | $107.41 | 2,132 | 228,991 | 18,087 | Aug 23, 2023, 08:03 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Aug 21, 2023 | Sale | $107.41 | 1,600 | 171,862 | 6,193 | Aug 23, 2023, 08:01 PM |
| BENEVICH ERIC | Chief Commercial Officer | Aug 21, 2023 | Sale | $107.40 | 1,600 | 171,836 | 36,436 | Aug 23, 2023, 07:59 PM |
| ABERNETHY MATT | Chief Financial Officer | Aug 21, 2023 | Sale | $107.39 | 2,132 | 228,958 | 27,131 | Aug 23, 2023, 07:58 PM |
| RASTETTER WILLIAM H | Director | May 01, 2023 | Option Exercise | $12.71 | 7,625 | 96,914 | 47,085 | May 03, 2023, 05:34 PM |
| RASTETTER WILLIAM H | Director | May 01, 2023 | Sale | $101.43 | 4,300 | 436,135 | 42,785 | May 03, 2023, 05:34 PM |
| Cooke Julie | Chief Human Resources Officer | May 01, 2023 | Sale | $103.89 | 11,397 | 1,184,049 | 16,169 | May 03, 2023, 05:28 PM |
| Cooke Julie | Chief Human Resources Officer | Apr 25, 2023 | Sale | $103.82 | 100 | 10,382 | 27,561 | Apr 27, 2023, 04:37 PM |
| ROBERTS EIRY | Chief Medical Officer | Apr 24, 2023 | Sale | $103.48 | 14,400 | 1,490,059 | 26,644 | Apr 26, 2023, 09:22 PM |
| RASTETTER WILLIAM H | Director | Apr 21, 2023 | Option Exercise | $12.71 | 10,765 | 136,823 | 45,494 | Apr 21, 2023, 06:58 PM |
| RASTETTER WILLIAM H | Director | Apr 19, 2023 | Option Exercise | $12.71 | 1,610 | 20,463 | 35,632 | Apr 21, 2023, 06:58 PM |
| RASTETTER WILLIAM H | Director | Apr 21, 2023 | Sale | $105.04 | 6,034 | 633,787 | 39,460 | Apr 21, 2023, 06:58 PM |
| RASTETTER WILLIAM H | Director | Apr 19, 2023 | Sale | $105.00 | 903 | 94,819 | 34,729 | Apr 21, 2023, 06:58 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 06, 2023 | Sale | $104.90 | 1,215 | 127,459 | 16,501 | Feb 08, 2023, 07:56 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 08, 2023 | Sale | $103.83 | 1,328 | 137,883 | 28,052 | Feb 08, 2023, 07:56 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 07, 2023 | Sale | $102.49 | 14,536 | 1,489,779 | 28,246 | Feb 08, 2023, 07:56 PM |
| ROBERTS EIRY | Chief Medical Officer | Feb 08, 2023 | Sale | $104.16 | 980 | 102,072 | 41,015 | Feb 08, 2023, 07:40 PM |
| ROBERTS EIRY | Chief Medical Officer | Feb 07, 2023 | Sale | $102.40 | 14,424 | 1,477,032 | 40,135 | Feb 08, 2023, 07:40 PM |
| ROBERTS EIRY | Chief Medical Officer | Feb 06, 2023 | Sale | $105.80 | 1,121 | 118,602 | 27,176 | Feb 08, 2023, 07:40 PM |
| Onyia Jude | Chief Scientific Officer | Feb 07, 2023 | Sale | $102.30 | 4,508 | 461,166 | 6,525 | Feb 08, 2023, 07:38 PM |
| Lloyd-Smith Malcolm | Chief Integration Officer | Feb 07, 2023 | Sale | $102.39 | 13,816 | 1,414,654 | 41,710 | Feb 08, 2023, 07:35 PM |
| Lloyd-Smith Malcolm | Chief Integration Officer | Feb 06, 2023 | Sale | $105.82 | 801 | 84,758 | 29,300 | Feb 08, 2023, 07:35 PM |
| Lloyd-Smith Malcolm | Chief Integration Officer | Feb 08, 2023 | Sale | $103.83 | 701 | 72,785 | 42,337 | Feb 08, 2023, 07:35 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 08, 2023 | Sale | $104.08 | 911 | 94,815 | 44,973 | Feb 08, 2023, 07:32 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 07, 2023 | Sale | $102.40 | 14,323 | 1,466,680 | 44,157 | Feb 08, 2023, 07:32 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 06, 2023 | Sale | $105.80 | 1,041 | 110,141 | 31,290 | Feb 08, 2023, 07:32 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 06, 2023 | Sale | $105.68 | 3,040 | 321,259 | 468,008 | Feb 08, 2023, 07:28 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 08, 2023 | Sale | $104.30 | 2,274 | 237,185 | 491,365 | Feb 08, 2023, 07:28 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 07, 2023 | Sale | $102.42 | 23,730 | 2,430,315 | 489,322 | Feb 08, 2023, 07:28 PM |
| Gano Kyle | Chief Business Development Off | Feb 08, 2023 | Sale | $103.99 | 980 | 101,910 | 128,096 | Feb 08, 2023, 07:25 PM |
| Gano Kyle | Chief Business Development Off | Feb 07, 2023 | Sale | $102.40 | 14,424 | 1,476,982 | 127,216 | Feb 08, 2023, 07:25 PM |
| Gano Kyle | Chief Business Development Off | Feb 06, 2023 | Sale | $105.64 | 1,600 | 169,028 | 114,257 | Feb 08, 2023, 07:25 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Feb 06, 2023 | Sale | $105.61 | 240 | 25,346 | 4,127 | Feb 08, 2023, 07:22 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Feb 08, 2023 | Sale | $104.11 | 700 | 72,876 | 4,755 | Feb 08, 2023, 07:22 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Feb 07, 2023 | Sale | $102.42 | 24,298 | 2,488,519 | 15,624 | Feb 08, 2023, 07:22 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 08, 2023 | Sale | $104.12 | 980 | 102,036 | 34,381 | Feb 08, 2023, 07:18 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 07, 2023 | Sale | $102.41 | 17,390 | 1,780,868 | 33,501 | Feb 08, 2023, 07:18 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 06, 2023 | Sale | $105.63 | 1,280 | 135,201 | 17,879 | Feb 08, 2023, 07:18 PM |
| ABERNETHY MATT | Chief Financial Officer | Feb 06, 2023 | Sale | $105.67 | 1,280 | 135,253 | 22,507 | Feb 08, 2023, 07:16 PM |
| ABERNETHY MATT | Chief Financial Officer | Feb 08, 2023 | Sale | $104.19 | 980 | 102,110 | 25,213 | Feb 08, 2023, 07:16 PM |
| ABERNETHY MATT | Chief Financial Officer | Feb 07, 2023 | Sale | $102.40 | 26,328 | 2,696,107 | 35,824 | Feb 08, 2023, 07:16 PM |
| ROBERTS EIRY | Chief Medical Officer | Jan 31, 2023 | Sale | $109.99 | 1,457 | 160,254 | 26,171 | Feb 02, 2023, 05:28 PM |
| Onyia Jude | Chief Scientific Officer | Jan 31, 2023 | Sale | $108.48 | 126 | 13,668 | 2,477 | Feb 02, 2023, 05:26 PM |
| Lloyd-Smith Malcolm | Chief Integration Officer | Jan 31, 2023 | Sale | $110.02 | 1,666 | 183,290 | 28,582 | Feb 02, 2023, 05:24 PM |
| Lippoldt Darin | Chief Legal Officer | Jan 31, 2023 | Sale | $109.97 | 1,250 | 137,464 | 30,357 | Feb 02, 2023, 05:21 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 31, 2023 | Sale | $110.08 | 2,707 | 297,997 | 465,278 | Feb 02, 2023, 05:19 PM |
| Gano Kyle | Chief Business Development Off | Jan 31, 2023 | Sale | $109.98 | 1,541 | 169,486 | 112,820 | Feb 02, 2023, 05:15 PM |
| Cooke Julie | Chief Human Resources Officer | Jan 31, 2023 | Sale | $108.48 | 916 | 99,368 | 15,926 | Feb 02, 2023, 05:07 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Jan 31, 2023 | Sale | $109.92 | 1,104 | 121,349 | 3,911 | Feb 02, 2023, 05:04 PM |
| BENEVICH ERIC | Chief Commercial Officer | Jan 31, 2023 | Sale | $109.95 | 1,207 | 132,710 | 16,729 | Feb 02, 2023, 05:00 PM |
| ABERNETHY MATT | Chief Financial Officer | Jan 31, 2023 | Sale | $109.98 | 1,283 | 141,108 | 21,357 | Feb 02, 2023, 04:53 PM |
| BENEVICH ERIC | Chief Commercial Officer | Jan 06, 2023 | Option Exercise | $43.24 | 400 | 17,296 | 16,043 | Jan 10, 2023, 05:13 PM |
| BENEVICH ERIC | Chief Commercial Officer | Jan 06, 2023 | Sale | $125.00 | 400 | 50,000 | 15,643 | Jan 10, 2023, 05:13 PM |
| SHERWIN STEPHEN A | Director | Jan 03, 2023 | Option Exercise | $12.84 | 30,000 | 385,350 | 40,055 | Jan 05, 2023, 06:21 PM |
| SHERWIN STEPHEN A | Director | Jan 03, 2023 | Sale | $118.86 | 30,000 | 3,565,728 | 25,055 | Jan 05, 2023, 06:21 PM |
| POPS RICHARD F | Director | Jan 03, 2023 | Option Exercise | $12.71 | 15,000 | 190,650 | 44,512 | Jan 05, 2023, 06:18 PM |
| POPS RICHARD F | Director | Jan 03, 2023 | Sale | $119.20 | 15,000 | 1,788,045 | 29,512 | Jan 05, 2023, 06:18 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 30, 2022 | Option Exercise | $41.47 | 50,000 | 2,073,275 | 37,805 | Dec 01, 2022, 06:43 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 30, 2022 | Sale | $125.90 | 50,000 | 6,295,100 | 15,643 | Dec 01, 2022, 06:43 PM |
| Onyia Jude | Chief Scientific Officer | Nov 29, 2022 | Sale | $121.90 | 2,331 | 284,161 | 2,366 | Dec 01, 2022, 06:35 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 10, 2022 | Option Exercise | $41.78 | 100 | 4,178 | 15,743 | Nov 10, 2022, 05:50 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 08, 2022 | Option Exercise | $41.78 | 24,593 | 1,027,496 | 40,236 | Nov 10, 2022, 05:50 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 10, 2022 | Sale | $125.36 | 100 | 12,536 | 15,643 | Nov 10, 2022, 05:50 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 08, 2022 | Sale | $125.33 | 24,593 | 3,082,314 | 15,643 | Nov 10, 2022, 05:50 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 08, 2022 | Option Exercise | $43.24 | 5,082 | 219,746 | 34,316 | Nov 10, 2022, 05:48 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 08, 2022 | Sale | $125.04 | 5,082 | 635,443 | 29,234 | Nov 10, 2022, 05:48 PM |
| Cooke Julie | Chief Human Resources Officer | Nov 08, 2022 | Option Exercise | $81.05 | 5,592 | 453,232 | 20,694 | Nov 10, 2022, 05:47 PM |
| Cooke Julie | Chief Human Resources Officer | Nov 08, 2022 | Sale | $124.99 | 5,592 | 698,950 | 15,102 | Nov 10, 2022, 05:47 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 03, 2022 | Option Exercise | $43.24 | 4,518 | 195,358 | 33,752 | Nov 04, 2022, 05:51 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 03, 2022 | Sale | $125.02 | 4,518 | 564,849 | 29,234 | Nov 04, 2022, 05:51 PM |
| Cooke Julie | Chief Human Resources Officer | Nov 02, 2022 | Option Exercise | $81.05 | 1,144 | 92,721 | 16,246 | Nov 04, 2022, 05:02 PM |
| Cooke Julie | Chief Human Resources Officer | Nov 03, 2022 | Option Exercise | $81.05 | 7,264 | 588,747 | 22,366 | Nov 04, 2022, 05:02 PM |
| Cooke Julie | Chief Human Resources Officer | Nov 03, 2022 | Sale | $125.00 | 7,264 | 908,036 | 15,102 | Nov 04, 2022, 05:02 PM |
| Cooke Julie | Chief Human Resources Officer | Nov 02, 2022 | Sale | $124.97 | 1,144 | 142,962 | 15,102 | Nov 04, 2022, 05:02 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 03, 2022 | Option Exercise | $41.78 | 8,968 | 374,683 | 24,611 | Nov 04, 2022, 04:56 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 02, 2022 | Option Exercise | $41.78 | 400 | 16,712 | 16,043 | Nov 04, 2022, 04:56 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 03, 2022 | Sale | $125.02 | 8,968 | 1,121,179 | 15,643 | Nov 04, 2022, 04:56 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 02, 2022 | Sale | $125.00 | 400 | 50,000 | 15,643 | Nov 04, 2022, 04:56 PM |
| LYONS GARY A | Director | Oct 31, 2022 | Option Exercise | $12.71 | 15,000 | 190,650 | 218,697 | Nov 02, 2022, 06:42 PM |
| LYONS GARY A | Director | Oct 31, 2022 | Sale | $114.76 | 15,000 | 1,721,400 | 203,697 | Nov 02, 2022, 06:42 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 02, 2022 | Option Exercise | $43.24 | 400 | 17,296 | 29,634 | Nov 02, 2022, 06:33 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 01, 2022 | Option Exercise | $43.24 | 10,000 | 432,400 | 39,234 | Nov 02, 2022, 06:33 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 02, 2022 | Sale | $125.00 | 400 | 50,000 | 29,234 | Nov 02, 2022, 06:33 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 01, 2022 | Sale | $120.09 | 10,000 | 1,200,900 | 29,234 | Nov 02, 2022, 06:33 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Oct 31, 2022 | Sale | $114.12 | 1,295 | 147,785 | 2,919 | Nov 02, 2022, 06:28 PM |
| Lippoldt Darin | Chief Legal Officer | Oct 27, 2022 | Option Exercise | $43.24 | 4,923 | 212,871 | 34,157 | Oct 28, 2022, 05:45 PM |
| Lippoldt Darin | Chief Legal Officer | Oct 26, 2022 | Option Exercise | $43.24 | 5,077 | 219,529 | 34,311 | Oct 28, 2022, 05:45 PM |
| Lippoldt Darin | Chief Legal Officer | Oct 26, 2022 | Sale | $115.02 | 5,077 | 583,967 | 29,234 | Oct 28, 2022, 05:45 PM |
| Lippoldt Darin | Chief Legal Officer | Oct 27, 2022 | Sale | $115.04 | 4,923 | 566,332 | 29,234 | Oct 28, 2022, 05:45 PM |
| BENEVICH ERIC | Chief Commercial Officer | Oct 17, 2022 | Sale | $110.82 | 4,960 | 549,682 | 15,643 | Oct 19, 2022, 05:55 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Oct 03, 2022 | Sale | $106.59 | 1,437 | 153,170 | 4,214 | Oct 05, 2022, 07:07 PM |
| LYONS GARY A | Director | Oct 04, 2022 | Sale | $110.54 | 5,000 | 552,710 | 203,697 | Oct 05, 2022, 07:00 PM |
| Lippoldt Darin | Chief Legal Officer | Oct 04, 2022 | Option Exercise | $43.24 | 10,000 | 432,400 | 39,234 | Oct 05, 2022, 06:33 PM |
| Lippoldt Darin | Chief Legal Officer | Oct 04, 2022 | Sale | $111.04 | 10,000 | 1,110,450 | 29,234 | Oct 05, 2022, 06:33 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Aug 15, 2022 | Option Exercise | $45.96 | 8,043 | 369,663 | 26,931 | Aug 16, 2022, 06:44 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Aug 12, 2022 | Option Exercise | $35.99 | 21,533 | 774,973 | 40,421 | Aug 16, 2022, 06:44 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Aug 12, 2022 | Sale | $105.95 | 21,533 | 2,281,335 | 18,888 | Aug 16, 2022, 06:44 PM |
| Cooke Julie | Chief Human Resources Officer | Aug 05, 2022 | Sale | $100.00 | 1,816 | 181,600 | 15,102 | Aug 09, 2022, 06:54 PM |
| Cooke Julie | Chief Human Resources Officer | Jun 27, 2022 | Sale | $100.00 | 754 | 75,400 | 16,918 | Jun 29, 2022, 04:26 PM |
| POPS RICHARD F | Director | May 09, 2022 | Option Exercise | $6.66 | 15,000 | 99,900 | 37,012 | May 11, 2022, 05:36 PM |
| POPS RICHARD F | Director | May 09, 2022 | Sale | $76.30 | 15,000 | 1,144,463 | 29,512 | May 11, 2022, 05:36 PM |
| LYONS GARY A | Director | Apr 25, 2022 | Option Exercise | $6.66 | 15,000 | 99,900 | 223,697 | Apr 27, 2022, 05:26 PM |
| LYONS GARY A | Director | Apr 25, 2022 | Sale | $92.76 | 15,000 | 1,391,392 | 208,697 | Apr 27, 2022, 05:26 PM |
| RASTETTER WILLIAM H | Director | Apr 01, 2022 | Option Exercise | $6.66 | 20,000 | 133,200 | 44,750 | Apr 05, 2022, 06:20 PM |
| RASTETTER WILLIAM H | Director | Apr 01, 2022 | Sale | $94.93 | 10,728 | 1,018,366 | 34,022 | Apr 05, 2022, 06:20 PM |
| Lippoldt Darin | Chief Legal Officer | Mar 22, 2022 | Sale | $95.05 | 8,455 | 803,656 | 29,396 | Mar 22, 2022, 06:55 PM |
| Lippoldt Darin | Chief Legal Officer | Mar 18, 2022 | Sale | $95.00 | 300 | 28,500 | 37,851 | Mar 22, 2022, 06:55 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Feb 08, 2022 | Sale | $79.62 | 700 | 55,736 | 2,919 | Feb 09, 2022, 08:04 PM |
| Boyer David W. | Chief Corp. Affairs Officer | Feb 07, 2022 | Sale | $81.07 | 240 | 19,457 | 2,291 | Feb 09, 2022, 08:04 PM |
| ROBERTS EIRY | Chief Medical Officer | Feb 07, 2022 | Sale | $80.78 | 2,744 | 221,660 | 23,746 | Feb 09, 2022, 07:06 PM |
| ROBERTS EIRY | Chief Medical Officer | Feb 08, 2022 | Sale | $79.52 | 980 | 77,931 | 24,625 | Feb 09, 2022, 07:06 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 08, 2022 | Sale | $79.53 | 701 | 55,751 | 18,731 | Feb 09, 2022, 07:04 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 07, 2022 | Sale | $80.72 | 2,681 | 216,417 | 18,104 | Feb 09, 2022, 07:04 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 08, 2022 | Sale | $79.51 | 911 | 72,435 | 38,112 | Feb 09, 2022, 07:03 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 07, 2022 | Sale | $80.72 | 3,168 | 255,725 | 37,296 | Feb 09, 2022, 07:03 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 07, 2022 | Sale | $80.82 | 8,710 | 703,907 | 460,801 | Feb 09, 2022, 07:00 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 08, 2022 | Sale | $79.49 | 2,274 | 180,768 | 462,844 | Feb 09, 2022, 07:00 PM |
| Gano Kyle | Chief Business Development Off | Feb 08, 2022 | Sale | $79.67 | 980 | 78,079 | 111,173 | Feb 09, 2022, 06:58 PM |
| Gano Kyle | Chief Business Development Off | Feb 07, 2022 | Sale | $80.77 | 5,900 | 476,549 | 110,294 | Feb 09, 2022, 06:58 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 08, 2022 | Sale | $79.56 | 700 | 55,689 | 17,411 | Feb 09, 2022, 06:55 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 07, 2022 | Sale | $80.65 | 2,158 | 174,038 | 16,783 | Feb 09, 2022, 06:55 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 08, 2022 | Sale | $79.67 | 980 | 78,073 | 20,338 | Feb 09, 2022, 06:53 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 07, 2022 | Sale | $80.78 | 4,119 | 332,748 | 19,459 | Feb 09, 2022, 06:53 PM |
| ABERNETHY MATT | Chief Financial Officer | Feb 08, 2022 | Sale | $79.65 | 980 | 78,058 | 20,204 | Feb 09, 2022, 06:51 PM |
| ABERNETHY MATT | Chief Financial Officer | Feb 07, 2022 | Sale | $80.79 | 3,310 | 267,428 | 19,325 | Feb 09, 2022, 06:51 PM |
| SHERWIN STEPHEN A | Director | Jan 24, 2022 | Option Exercise | $6.66 | 15,000 | 99,900 | 40,055 | Jan 26, 2022, 05:52 PM |
| SHERWIN STEPHEN A | Director | Jan 24, 2022 | Sale | $74.43 | 15,000 | 1,116,378 | 25,055 | Jan 26, 2022, 05:52 PM |
| ROBERTS EIRY | Chief Medical Officer | Jan 10, 2022 | Sale | $74.50 | 2,632 | 196,088 | 21,279 | Jan 12, 2022, 05:53 PM |
| Gano Kyle | Chief Business Development Off | Jan 05, 2022 | Option Exercise | $8.66 | 28,266 | 244,784 | 133,250 | Jan 07, 2022, 06:04 PM |
| Gano Kyle | Chief Business Development Off | Jan 05, 2022 | Sale | $85.50 | 28,266 | 2,416,751 | 104,984 | Jan 07, 2022, 06:04 PM |
| ABERNETHY MATT | Chief Financial Officer | Dec 01, 2021 | Sale | $82.59 | 1,645 | 135,852 | 16,349 | Dec 03, 2021, 05:02 PM |
| LYONS GARY A | Director | Oct 07, 2021 | Sale | $105.06 | 5,000 | 525,295 | 208,697 | Oct 12, 2021, 06:34 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Oct 07, 2021 | Option Exercise | $43.24 | 5,000 | 216,200 | 87,273 | Oct 12, 2021, 06:32 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Oct 07, 2021 | Sale | $104.81 | 8,000 | 838,510 | 82,273 | Oct 12, 2021, 06:32 PM |
| Cooke Julie | Chief Human Resources Officer | Oct 04, 2021 | Sale | $101.73 | 987 | 100,408 | 14,841 | Oct 06, 2021, 04:37 PM |
| BENEVICH ERIC | Chief Commercial Officer | Aug 16, 2021 | Sale | $89.62 | 5,628 | 504,395 | 15,608 | Aug 18, 2021, 06:18 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Jul 27, 2021 | Sale | $93.80 | 16,709 | 1,567,336 | 15,801 | Jul 29, 2021, 05:32 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 10, 2021 | Option Exercise | $35.99 | 1,700 | 61,183 | 33,610 | Feb 12, 2021, 08:27 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 10, 2021 | Sale | $119.96 | 1,700 | 203,925 | 32,510 | Feb 12, 2021, 08:27 PM |
| Gano Kyle | Chief Business Development Off | Feb 08, 2021 | Sale | $116.85 | 3,693 | 431,518 | 104,768 | Feb 09, 2021, 09:42 PM |
| Gano Kyle | Chief Business Development Off | Feb 05, 2021 | Sale | $114.00 | 2,677 | 305,185 | 100,439 | Feb 09, 2021, 09:42 PM |
| ABERNETHY MATT | Chief Financial Officer | Feb 08, 2021 | Sale | $116.82 | 2,910 | 339,942 | 14,869 | Feb 09, 2021, 09:30 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 08, 2021 | Sale | $116.80 | 3,842 | 448,748 | 157,651 | Feb 09, 2021, 09:27 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 05, 2021 | Sale | $113.79 | 704 | 80,108 | 153,328 | Feb 09, 2021, 09:27 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 08, 2021 | Sale | $116.83 | 4,270 | 498,843 | 21,099 | Feb 09, 2021, 09:26 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 05, 2021 | Sale | $114.03 | 809 | 92,247 | 16,434 | Feb 09, 2021, 09:26 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 08, 2021 | Sale | $116.73 | 1,338 | 156,189 | 13,737 | Feb 09, 2021, 09:24 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 05, 2021 | Sale | $113.86 | 605 | 68,887 | 12,125 | Feb 09, 2021, 09:24 PM |
| ROBERTS EIRY | Chief Medical Officer | Feb 08, 2021 | Sale | $116.78 | 2,363 | 275,944 | 18,693 | Feb 09, 2021, 09:21 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 08, 2021 | Sale | $116.81 | 3,261 | 380,928 | 32,510 | Feb 09, 2021, 09:20 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 05, 2021 | Sale | $114.15 | 865 | 98,739 | 29,675 | Feb 09, 2021, 09:20 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 08, 2021 | Sale | $116.69 | 2,708 | 315,999 | 85,273 | Feb 09, 2021, 09:18 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 05, 2021 | Sale | $113.76 | 605 | 68,822 | 82,169 | Feb 09, 2021, 09:18 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 08, 2021 | Sale | $116.75 | 10,466 | 1,221,862 | 452,972 | Feb 09, 2021, 09:17 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 05, 2021 | Sale | $114.16 | 2,422 | 276,505 | 443,249 | Feb 09, 2021, 09:17 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 09, 2021 | Option Exercise | $35.99 | 36,194 | 1,302,622 | 64,361 | Feb 09, 2021, 09:16 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 08, 2021 | Sale | $116.72 | 3,407 | 397,675 | 34,361 | Feb 09, 2021, 09:16 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 05, 2021 | Sale | $114.05 | 605 | 69,003 | 30,627 | Feb 09, 2021, 09:16 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 09, 2021 | Sale | $116.17 | 36,194 | 4,204,824 | 34,361 | Feb 09, 2021, 09:16 PM |
| LYONS GARY A | Director | Jan 26, 2021 | Sale | $120.00 | 400 | 48,000 | 223,697 | Jan 27, 2021, 09:53 PM |
| LYONS GARY A | Director | Jan 25, 2021 | Sale | $120.03 | 1,600 | 192,046 | 224,097 | Jan 27, 2021, 09:53 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Jan 25, 2021 | Option Exercise | $34.46 | 17,570 | 605,470 | 37,960 | Jan 27, 2021, 09:30 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Jan 26, 2021 | Option Exercise | $35.99 | 1,100 | 39,589 | 29,602 | Jan 27, 2021, 09:30 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Jan 26, 2021 | Sale | $119.97 | 1,100 | 131,966 | 29,002 | Jan 27, 2021, 09:30 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Jan 25, 2021 | Sale | $119.97 | 17,570 | 2,107,814 | 29,002 | Jan 27, 2021, 09:30 PM |
| BENEVICH ERIC | Chief Commercial Officer | Jan 26, 2021 | Option Exercise | $41.78 | 300 | 12,534 | 16,105 | Jan 27, 2021, 08:58 PM |
| BENEVICH ERIC | Chief Commercial Officer | Jan 25, 2021 | Option Exercise | $41.78 | 3,477 | 145,269 | 20,882 | Jan 27, 2021, 08:58 PM |
| BENEVICH ERIC | Chief Commercial Officer | Jan 26, 2021 | Sale | $120.00 | 400 | 48,000 | 15,805 | Jan 27, 2021, 08:58 PM |
| BENEVICH ERIC | Chief Commercial Officer | Jan 25, 2021 | Sale | $120.03 | 5,077 | 609,370 | 17,405 | Jan 27, 2021, 08:58 PM |
| ROBERTS EIRY | Chief Medical Officer | Jan 08, 2021 | Sale | $111.06 | 2,632 | 292,297 | 15,845 | Jan 12, 2021, 04:17 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 08, 2021 | Option Exercise | $8.65 | 308,250 | 2,667,797 | 605,872 | Jan 12, 2021, 04:16 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 08, 2021 | Sale | $110.22 | 308,250 | 33,973,945 | 441,071 | Jan 12, 2021, 04:16 PM |
| ABERNETHY MATT | Chief Financial Officer | Dec 01, 2020 | Sale | $94.66 | 1,645 | 155,721 | 11,494 | Dec 02, 2020, 04:12 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 12, 2020 | Sale | $90.71 | 2,257 | 204,723 | 17,405 | Nov 16, 2020, 06:27 PM |
| ROBERTS EIRY | Chief Medical Officer | Nov 12, 2020 | Sale | $90.74 | 2,257 | 204,810 | 13,477 | Nov 16, 2020, 06:23 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Nov 12, 2020 | Sale | $90.73 | 2,257 | 204,776 | 29,002 | Nov 16, 2020, 06:21 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 12, 2020 | Sale | $90.72 | 2,257 | 204,755 | 30,082 | Nov 16, 2020, 06:20 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Nov 12, 2020 | Sale | $90.73 | 2,257 | 204,784 | 81,624 | Nov 16, 2020, 06:19 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Nov 12, 2020 | Sale | $90.78 | 3,390 | 307,748 | 441,071 | Nov 16, 2020, 06:16 PM |
| Gano Kyle | Chief Business Development Off | Nov 12, 2020 | Sale | $90.73 | 2,257 | 204,770 | 98,028 | Nov 16, 2020, 06:11 PM |
| Cooke Julie | Chief Human Resources Officer | Nov 12, 2020 | Sale | $90.73 | 2,257 | 204,778 | 11,580 | Nov 16, 2020, 06:10 PM |
| Bozigian Haig P. | Chief Development Officer | Nov 12, 2020 | Sale | $90.74 | 2,257 | 204,806 | 152,694 | Nov 16, 2020, 06:08 PM |
| ABERNETHY MATT | Chief Financial Officer | Nov 12, 2020 | Sale | $90.74 | 2,257 | 204,810 | 10,014 | Nov 16, 2020, 06:02 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 02, 2020 | Option Exercise | $35.99 | 20,595 | 741,214 | 35,969 | Nov 04, 2020, 06:09 PM |
| BENEVICH ERIC | Chief Commercial Officer | Nov 02, 2020 | Sale | $96.53 | 20,595 | 1,987,972 | 15,374 | Nov 04, 2020, 06:09 PM |
| Cooke Julie | Chief Human Resources Officer | Oct 02, 2020 | Sale | $95.26 | 987 | 94,022 | 9,549 | Oct 06, 2020, 04:05 PM |
| ROBERTS EIRY | Chief Medical Officer | Aug 05, 2020 | Sale | $118.84 | 2,257 | 268,224 | 11,446 | Aug 07, 2020, 07:51 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Aug 05, 2020 | Sale | $118.86 | 2,257 | 268,278 | 26,971 | Aug 07, 2020, 07:47 PM |
| Lippoldt Darin | Chief Legal Officer | Aug 05, 2020 | Sale | $118.87 | 2,257 | 268,296 | 28,051 | Aug 07, 2020, 07:40 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Aug 05, 2020 | Sale | $118.83 | 2,257 | 268,199 | 79,593 | Aug 07, 2020, 07:36 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Aug 05, 2020 | Sale | $118.91 | 3,390 | 403,101 | 438,021 | Aug 07, 2020, 07:29 PM |
| Gano Kyle | Chief Business Development Off | Aug 05, 2020 | Sale | $118.87 | 2,257 | 268,285 | 95,997 | Aug 07, 2020, 07:24 PM |
| Cooke Julie | Chief Human Resources Officer | Aug 05, 2020 | Sale | $118.91 | 2,257 | 268,382 | 8,661 | Aug 07, 2020, 07:21 PM |
| Bozigian Haig P. | Chief Development Officer | Aug 05, 2020 | Sale | $118.89 | 2,257 | 268,323 | 150,663 | Aug 07, 2020, 07:14 PM |
| BENEVICH ERIC | Chief Commercial Officer | Aug 05, 2020 | Sale | $118.85 | 2,257 | 268,253 | 15,374 | Aug 07, 2020, 06:35 PM |
| ABERNETHY MATT | Chief Financial Officer | Aug 05, 2020 | Sale | $118.90 | 2,257 | 268,355 | 7,983 | Aug 07, 2020, 06:22 PM |
| Lippoldt Darin | Chief Legal Officer | Jul 09, 2020 | Option Exercise | $35.99 | 1,657 | 59,635 | 27,678 | Jul 10, 2020, 04:26 PM |
| Lippoldt Darin | Chief Legal Officer | Jul 09, 2020 | Sale | $136.02 | 1,657 | 225,385 | 26,021 | Jul 10, 2020, 04:26 PM |
| ROBERTS EIRY | Chief Medical Officer | Jun 23, 2020 | Option Exercise | $77.81 | 5,000 | 389,050 | 14,416 | Jun 25, 2020, 04:19 PM |
| ROBERTS EIRY | Chief Medical Officer | Jun 23, 2020 | Sale | $130.00 | 5,000 | 650,000 | 9,416 | Jun 25, 2020, 04:19 PM |
| Lippoldt Darin | Chief Legal Officer | Jun 23, 2020 | Option Exercise | $32.99 | 5,000 | 164,950 | 31,021 | Jun 25, 2020, 04:15 PM |
| Lippoldt Darin | Chief Legal Officer | Jun 23, 2020 | Sale | $130.00 | 5,000 | 650,000 | 26,021 | Jun 25, 2020, 04:15 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 11, 2020 | Option Exercise | $35.90 | 5,571 | 199,976 | 77,563 | Jun 15, 2020, 05:31 PM |
| Lippoldt Darin | Chief Legal Officer | May 18, 2020 | Option Exercise | $32.99 | 5,000 | 164,950 | 31,021 | May 20, 2020, 07:15 PM |
| Lippoldt Darin | Chief Legal Officer | May 18, 2020 | Sale | $120.00 | 5,000 | 600,000 | 26,021 | May 20, 2020, 07:15 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | May 19, 2020 | Option Exercise | $35.99 | 10,000 | 359,900 | 114,741 | May 20, 2020, 06:59 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | May 18, 2020 | Option Exercise | $35.99 | 10,000 | 359,900 | 114,741 | May 20, 2020, 06:59 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | May 19, 2020 | Sale | $126.55 | 42,749 | 5,409,950 | 104,741 | May 20, 2020, 06:59 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | May 18, 2020 | Sale | $119.98 | 10,000 | 1,199,800 | 104,741 | May 20, 2020, 06:59 PM |
| Bozigian Haig P. | Chief Development Officer | May 12, 2020 | Option Exercise | $63.10 | 61,555 | 3,884,054 | 167,204 | May 14, 2020, 08:09 PM |
| Bozigian Haig P. | Chief Development Officer | May 12, 2020 | Sale | $114.94 | 61,555 | 7,075,378 | 148,633 | May 14, 2020, 08:09 PM |
| ABERNETHY MATT | Chief Financial Officer | May 07, 2020 | Option Exercise | $73.60 | 15,000 | 1,104,000 | 20,953 | May 11, 2020, 08:17 PM |
| ABERNETHY MATT | Chief Financial Officer | May 07, 2020 | Sale | $110.21 | 15,000 | 1,653,135 | 5,953 | May 11, 2020, 08:17 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | May 07, 2020 | Sale | $105.44 | 8,682 | 915,456 | 104,741 | May 11, 2020, 08:06 PM |
| SHERWIN STEPHEN A | Director | Apr 28, 2020 | Sale | $99.39 | 17,687 | 1,757,966 | 29,861 | Apr 30, 2020, 04:27 PM |
| ABERNETHY MATT | Chief Financial Officer | Apr 28, 2020 | Sale | $102.49 | 1,741 | 178,435 | 5,953 | Apr 30, 2020, 04:25 PM |
| ROBERTS EIRY | Chief Medical Officer | Apr 24, 2020 | Sale | $99.47 | 1,934 | 192,376 | 9,416 | Apr 28, 2020, 08:46 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Apr 24, 2020 | Sale | $99.45 | 1,934 | 192,329 | 24,941 | Apr 28, 2020, 08:44 PM |
| Lippoldt Darin | Chief Legal Officer | Apr 24, 2020 | Sale | $99.49 | 1,934 | 192,416 | 26,021 | Apr 28, 2020, 08:43 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Apr 24, 2020 | Sale | $99.41 | 1,934 | 192,258 | 113,423 | Apr 28, 2020, 08:42 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Apr 24, 2020 | Sale | $99.45 | 2,906 | 289,016 | 434,971 | Apr 28, 2020, 08:41 PM |
| Gano Kyle | Chief Business Development Off | Apr 24, 2020 | Sale | $99.47 | 1,934 | 192,377 | 93,967 | Apr 28, 2020, 08:40 PM |
| Cooke Julie | Chief Human Resources Officer | Apr 24, 2020 | Sale | $99.46 | 1,934 | 192,364 | 6,631 | Apr 28, 2020, 08:38 PM |
| Bozigian Haig P. | Chief Development Officer | Apr 24, 2020 | Sale | $99.46 | 1,934 | 192,351 | 148,633 | Apr 28, 2020, 08:35 PM |
| BENEVICH ERIC | Chief Commercial Officer | Apr 24, 2020 | Sale | $99.45 | 1,934 | 192,338 | 13,344 | Apr 28, 2020, 08:33 PM |
| ABERNETHY MATT | Chief Financial Officer | Apr 24, 2020 | Sale | $99.52 | 1,934 | 192,467 | 7,694 | Apr 28, 2020, 08:32 PM |
| BENEVICH ERIC | Chief Commercial Officer | Apr 15, 2020 | Sale | $94.65 | 8,632 | 817,018 | 11,603 | Apr 17, 2020, 09:48 PM |
| ROBERTS EIRY | Chief Medical Officer | Feb 07, 2020 | Sale | $103.31 | 1,623 | 167,675 | 7,452 | Feb 11, 2020, 07:23 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 10, 2020 | Option Exercise | $59.66 | 28,969 | 1,728,147 | 39,127 | Feb 11, 2020, 07:21 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 10, 2020 | Sale | $104.56 | 28,969 | 3,029,086 | 23,200 | Feb 11, 2020, 07:21 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 07, 2020 | Sale | $103.28 | 1,015 | 104,826 | 23,200 | Feb 11, 2020, 07:21 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 07, 2020 | Sale | $103.32 | 1,522 | 157,247 | 24,124 | Feb 11, 2020, 07:17 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 07, 2020 | Sale | $103.31 | 1,218 | 125,833 | 111,682 | Feb 11, 2020, 07:16 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 07, 2020 | Sale | $103.36 | 3,248 | 335,697 | 432,357 | Feb 11, 2020, 07:14 PM |
| Gano Kyle | Chief Business Development Off | Feb 07, 2020 | Sale | $103.33 | 1,623 | 167,711 | 91,975 | Feb 11, 2020, 07:13 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 07, 2020 | Sale | $103.26 | 913 | 94,276 | 4,643 | Feb 11, 2020, 07:10 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 07, 2020 | Sale | $103.33 | 1,623 | 167,701 | 146,641 | Feb 11, 2020, 07:09 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 07, 2020 | Sale | $103.32 | 2,030 | 209,748 | 20,087 | Feb 11, 2020, 07:08 PM |
| ABERNETHY MATT | Chief Financial Officer | Feb 07, 2020 | Sale | $103.35 | 2,030 | 209,807 | 5,701 | Feb 11, 2020, 07:06 PM |
| Gano Kyle | Chief Business Development Off | Feb 06, 2020 | Sale | $101.41 | 1,000 | 101,413 | 90,514 | Feb 07, 2020, 06:54 PM |
| Gano Kyle | Chief Business Development Off | Feb 05, 2020 | Sale | $103.05 | 3,690 | 380,262 | 89,614 | Feb 07, 2020, 06:54 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 06, 2020 | Sale | $101.44 | 803 | 81,456 | 110,587 | Feb 07, 2020, 06:50 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 05, 2020 | Sale | $103.15 | 1,618 | 166,894 | 109,865 | Feb 07, 2020, 06:50 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 06, 2020 | Sale | $101.51 | 1,490 | 151,257 | 22,287 | Feb 07, 2020, 06:47 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 05, 2020 | Sale | $103.05 | 1,948 | 200,734 | 21,127 | Feb 07, 2020, 06:47 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 06, 2020 | Sale | $101.46 | 1,198 | 121,555 | 22,755 | Feb 07, 2020, 06:46 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 05, 2020 | Sale | $102.97 | 1,750 | 180,206 | 21,678 | Feb 07, 2020, 06:46 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 05, 2020 | Sale | $103.09 | 5,449 | 561,726 | 425,529 | Feb 07, 2020, 06:44 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 06, 2020 | Sale | $101.56 | 4,343 | 441,066 | 429,436 | Feb 07, 2020, 06:44 PM |
| Cooke Julie | Chief Human Resources Officer | Feb 05, 2020 | Sale | $103.17 | 605 | 62,417 | 3,821 | Feb 07, 2020, 06:38 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 06, 2020 | Sale | $101.56 | 1,395 | 141,671 | 145,180 | Feb 07, 2020, 06:37 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 05, 2020 | Sale | $103.02 | 2,046 | 210,779 | 143,925 | Feb 07, 2020, 06:37 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 06, 2020 | Sale | $101.48 | 1,395 | 141,560 | 18,262 | Feb 07, 2020, 06:35 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 05, 2020 | Sale | $103.03 | 1,954 | 201,311 | 17,007 | Feb 07, 2020, 06:35 PM |
| ROBERTS EIRY | Chief Medical Officer | Jan 08, 2020 | Sale | $111.11 | 2,632 | 292,444 | 5,991 | Jan 10, 2020, 04:10 PM |
| ABERNETHY MATT | Chief Financial Officer | Dec 02, 2019 | Sale | $116.33 | 1,645 | 191,360 | 3,876 | Dec 04, 2019, 06:06 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Nov 18, 2019 | Option Exercise | $35.99 | 5,000 | 179,950 | 113,408 | Nov 19, 2019, 05:37 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Nov 18, 2019 | Sale | $115.98 | 5,000 | 579,900 | 108,408 | Nov 19, 2019, 05:37 PM |
| LYONS GARY A | Director | Nov 08, 2019 | Sale | $110.00 | 5,000 | 550,000 | 225,697 | Nov 13, 2019, 04:41 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 08, 2019 | Option Exercise | $32.99 | 10,000 | 329,900 | 26,728 | Nov 13, 2019, 04:36 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 08, 2019 | Sale | $110.01 | 10,000 | 1,100,057 | 20,103 | Nov 13, 2019, 04:36 PM |
| LYONS GARY A | Director | Nov 01, 2019 | Sale | $100.22 | 5,000 | 501,105 | 230,697 | Nov 05, 2019, 04:38 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Nov 01, 2019 | Option Exercise | $32.99 | 10,188 | 336,102 | 118,596 | Nov 05, 2019, 04:37 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Nov 01, 2019 | Sale | $100.34 | 10,188 | 1,022,295 | 108,408 | Nov 05, 2019, 04:37 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Oct 14, 2019 | Option Exercise | $15.45 | 9,956 | 153,820 | 29,569 | Oct 16, 2019, 04:20 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Oct 14, 2019 | Sale | $90.85 | 9,956 | 904,487 | 19,613 | Oct 16, 2019, 04:20 PM |
| Cooke Julie | Chief Human Resources Officer | Oct 02, 2019 | Sale | $88.56 | 987 | 87,409 | 3,276 | Oct 04, 2019, 06:15 PM |
| Lippoldt Darin | Chief Legal Officer | Sep 03, 2019 | Option Exercise | $32.99 | 6,736 | 222,221 | 26,839 | Sep 05, 2019, 04:09 PM |
| Lippoldt Darin | Chief Legal Officer | Sep 03, 2019 | Sale | $100.00 | 6,736 | 673,600 | 20,103 | Sep 05, 2019, 04:09 PM |
| Lippoldt Darin | Chief Legal Officer | Aug 27, 2019 | Option Exercise | $32.99 | 1,600 | 52,784 | 21,561 | Aug 27, 2019, 07:52 PM |
| Lippoldt Darin | Chief Legal Officer | Aug 23, 2019 | Option Exercise | $32.99 | 1,664 | 54,895 | 21,625 | Aug 27, 2019, 07:52 PM |
| Lippoldt Darin | Chief Legal Officer | Aug 27, 2019 | Sale | $100.00 | 1,600 | 160,000 | 19,961 | Aug 27, 2019, 07:52 PM |
| Lippoldt Darin | Chief Legal Officer | Aug 23, 2019 | Sale | $100.09 | 1,664 | 166,555 | 19,961 | Aug 27, 2019, 07:52 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Aug 09, 2019 | Option Exercise | $32.99 | 3,031 | 99,993 | 420,628 | Aug 13, 2019, 04:44 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Aug 08, 2019 | Option Exercise | $8.66 | 26,330 | 228,018 | 443,927 | Aug 08, 2019, 07:39 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Aug 07, 2019 | Option Exercise | $8.66 | 2,759 | 23,893 | 420,356 | Aug 08, 2019, 07:39 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Aug 06, 2019 | Option Exercise | $8.66 | 50,911 | 440,889 | 468,508 | Aug 08, 2019, 07:39 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Aug 08, 2019 | Sale | $95.64 | 26,330 | 2,518,154 | 417,597 | Aug 08, 2019, 07:39 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Aug 07, 2019 | Sale | $95.12 | 2,759 | 262,440 | 417,597 | Aug 08, 2019, 07:39 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Aug 06, 2019 | Sale | $95.15 | 50,911 | 4,844,380 | 417,597 | Aug 08, 2019, 07:39 PM |
| LYONS GARY A | Director | Jul 30, 2019 | Sale | $92.07 | 10,000 | 920,686 | 235,697 | Jul 31, 2019, 07:15 PM |
| Lippoldt Darin | Chief Legal Officer | Jul 30, 2019 | Option Exercise | $18.15 | 15,831 | 287,333 | 35,792 | Jul 31, 2019, 07:14 PM |
| Lippoldt Darin | Chief Legal Officer | Jul 30, 2019 | Sale | $92.13 | 15,831 | 1,458,569 | 19,961 | Jul 31, 2019, 07:14 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jul 30, 2019 | Option Exercise | $32.99 | 50,000 | 1,649,500 | 168,408 | Jul 31, 2019, 07:12 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jul 30, 2019 | Sale | $92.92 | 60,000 | 5,575,438 | 118,408 | Jul 31, 2019, 07:12 PM |
| Bozigian Haig P. | Chief Development Officer | Jul 30, 2019 | Option Exercise | $38.91 | 44,356 | 1,725,705 | 167,576 | Jul 31, 2019, 07:11 PM |
| Bozigian Haig P. | Chief Development Officer | Jul 30, 2019 | Sale | $92.77 | 44,356 | 4,114,858 | 141,976 | Jul 31, 2019, 07:11 PM |
| Bozigian Haig P. | Chief Development Officer | Jul 15, 2019 | Option Exercise | $32.99 | 30,680 | 1,012,133 | 172,656 | Jul 17, 2019, 07:08 PM |
| Bozigian Haig P. | Chief Development Officer | Jul 15, 2019 | Sale | $87.50 | 30,680 | 2,684,506 | 141,976 | Jul 17, 2019, 07:08 PM |
| BENEVICH ERIC | Chief Commercial Officer | Jul 15, 2019 | Sale | $87.44 | 5,835 | 510,201 | 14,910 | Jul 17, 2019, 07:06 PM |
| Bozigian Haig P. | Chief Development Officer | Jul 10, 2019 | Option Exercise | $32.99 | 7,120 | 234,889 | 149,096 | Jul 12, 2019, 04:15 PM |
| Bozigian Haig P. | Chief Development Officer | Jul 11, 2019 | Option Exercise | $32.99 | 100 | 3,299 | 142,076 | Jul 12, 2019, 04:15 PM |
| Bozigian Haig P. | Chief Development Officer | Jul 11, 2019 | Sale | $87.59 | 100 | 8,759 | 141,976 | Jul 12, 2019, 04:15 PM |
| Bozigian Haig P. | Chief Development Officer | Jul 10, 2019 | Sale | $87.63 | 7,120 | 623,958 | 141,976 | Jul 12, 2019, 04:15 PM |
| Bozigian Haig P. | Chief Development Officer | Jun 18, 2019 | Option Exercise | $32.99 | 2,100 | 69,279 | 144,076 | Jun 20, 2019, 05:56 PM |
| Bozigian Haig P. | Chief Development Officer | Jun 18, 2019 | Sale | $87.82 | 2,100 | 184,417 | 141,976 | Jun 20, 2019, 05:56 PM |
| Bozigian Haig P. | Chief Development Officer | Jun 13, 2019 | Option Exercise | $20.70 | 17,268 | 357,469 | 157,812 | Jun 17, 2019, 05:47 PM |
| Bozigian Haig P. | Chief Development Officer | Jun 13, 2019 | Sale | $82.62 | 17,268 | 1,426,628 | 141,976 | Jun 17, 2019, 05:47 PM |
| Bozigian Haig P. | Chief Development Officer | Jun 03, 2019 | Option Exercise | $19.59 | 3,435 | 67,292 | 145,411 | Jun 05, 2019, 06:26 PM |
| Bozigian Haig P. | Chief Development Officer | Jun 03, 2019 | Sale | $85.51 | 3,435 | 293,719 | 141,976 | Jun 05, 2019, 06:26 PM |
| Bozigian Haig P. | Chief Development Officer | May 31, 2019 | Option Exercise | $19.59 | 19,297 | 378,028 | 161,273 | Jun 03, 2019, 06:18 PM |
| Bozigian Haig P. | Chief Development Officer | May 31, 2019 | Sale | $85.02 | 19,297 | 1,640,581 | 141,976 | Jun 03, 2019, 06:18 PM |
| Bozigian Haig P. | Chief Development Officer | May 24, 2019 | Option Exercise | $19.59 | 17,486 | 342,551 | 159,462 | May 29, 2019, 05:45 PM |
| Bozigian Haig P. | Chief Development Officer | May 24, 2019 | Sale | $80.03 | 17,486 | 1,399,434 | 141,976 | May 29, 2019, 05:45 PM |
| Bozigian Haig P. | Chief Development Officer | May 22, 2019 | Option Exercise | $19.59 | 1,300 | 25,467 | 143,276 | May 23, 2019, 06:27 PM |
| Bozigian Haig P. | Chief Development Officer | May 22, 2019 | Sale | $80.03 | 1,300 | 104,037 | 141,976 | May 23, 2019, 06:27 PM |
| Bozigian Haig P. | Chief Development Officer | May 16, 2019 | Option Exercise | $17.58 | 66,667 | 1,171,789 | 176,352 | May 20, 2019, 06:36 PM |
| Bozigian Haig P. | Chief Development Officer | May 16, 2019 | Sale | $80.13 | 66,667 | 5,341,893 | 141,976 | May 20, 2019, 06:36 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | May 13, 2019 | Sale | $75.44 | 1,657 | 125,007 | 118,408 | May 15, 2019, 07:24 PM |
| Bozigian Haig P. | Chief Development Officer | May 13, 2019 | Option Exercise | $8.66 | 34,547 | 299,177 | 176,523 | May 15, 2019, 07:23 PM |
| Bozigian Haig P. | Chief Development Officer | May 13, 2019 | Sale | $75.51 | 34,547 | 2,608,813 | 141,976 | May 15, 2019, 07:23 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 06, 2019 | Sale | $83.58 | 920 | 76,894 | 19,238 | Feb 08, 2019, 05:11 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 06, 2019 | Sale | $83.52 | 791 | 66,063 | 19,646 | Feb 08, 2019, 05:10 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 06, 2019 | Sale | $84.03 | 531 | 44,622 | 120,065 | Feb 08, 2019, 05:09 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 06, 2019 | Sale | $84.22 | 4,096 | 344,986 | 417,597 | Feb 08, 2019, 05:09 PM |
| Gano Kyle | Chief Business Development Off | Feb 06, 2019 | Sale | $83.56 | 762 | 63,673 | 85,833 | Feb 08, 2019, 05:07 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 06, 2019 | Sale | $83.54 | 920 | 76,859 | 141,639 | Feb 08, 2019, 05:06 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 06, 2019 | Sale | $83.57 | 920 | 76,883 | 20,745 | Feb 08, 2019, 05:06 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 05, 2019 | Sale | $88.14 | 1,272 | 112,119 | 17,508 | Feb 06, 2019, 06:06 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 05, 2019 | Sale | $88.09 | 1,225 | 107,911 | 18,162 | Feb 06, 2019, 06:05 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 05, 2019 | Sale | $88.17 | 1,070 | 94,338 | 119,071 | Feb 06, 2019, 06:04 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 04, 2019 | Sale | $88.12 | 1,375 | 121,167 | 117,066 | Feb 06, 2019, 06:04 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 05, 2019 | Sale | $88.19 | 4,489 | 395,895 | 413,943 | Feb 06, 2019, 06:03 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 04, 2019 | Sale | $88.10 | 3,125 | 275,321 | 408,082 | Feb 06, 2019, 06:03 PM |
| Gano Kyle | Chief Business Development Off | Feb 05, 2019 | Sale | $88.12 | 2,434 | 214,482 | 84,695 | Feb 06, 2019, 06:03 PM |
| Gano Kyle | Chief Business Development Off | Feb 04, 2019 | Sale | $88.14 | 1,375 | 121,186 | 80,117 | Feb 06, 2019, 06:03 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 05, 2019 | Sale | $88.14 | 1,350 | 118,986 | 139,909 | Feb 06, 2019, 05:59 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 04, 2019 | Sale | $88.10 | 1,375 | 121,139 | 137,372 | Feb 06, 2019, 05:59 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 05, 2019 | Sale | $88.01 | 1,357 | 119,427 | 19,015 | Feb 06, 2019, 05:59 PM |
| ROBERTS EIRY | Chief Medical Officer | Jan 08, 2019 | Sale | $84.09 | 1,857 | 156,159 | 3,143 | Jan 10, 2019, 04:47 PM |
| ABERNETHY MATT | Chief Financial Officer | Dec 03, 2018 | Sale | $90.00 | 1,178 | 106,020 | 1,947 | Dec 06, 2018, 05:54 PM |
| POPS RICHARD F | Director | Nov 26, 2018 | Sale | $91.37 | 4,124 | 376,790 | 29,512 | Nov 27, 2018, 06:58 PM |
| POPS RICHARD F | Director | Nov 12, 2018 | Sale | $103.30 | 4,123 | 425,894 | 33,636 | Nov 13, 2018, 06:18 PM |
| Bozigian Haig P. | Chief Development Officer | Nov 08, 2018 | Option Exercise | $8.66 | 36,295 | 314,147 | 155,498 | Nov 13, 2018, 04:15 PM |
| Bozigian Haig P. | Chief Development Officer | Nov 08, 2018 | Sale | $110.00 | 36,295 | 3,992,450 | 135,997 | Nov 13, 2018, 04:15 PM |
| Bozigian Haig P. | Chief Development Officer | Nov 07, 2018 | Option Exercise | $12.62 | 29,399 | 371,105 | 151,043 | Nov 08, 2018, 05:04 PM |
| Bozigian Haig P. | Chief Development Officer | Nov 06, 2018 | Option Exercise | $35.99 | 9,420 | 339,026 | 145,417 | Nov 08, 2018, 05:04 PM |
| Bozigian Haig P. | Chief Development Officer | Nov 07, 2018 | Sale | $110.14 | 29,399 | 3,238,139 | 135,997 | Nov 08, 2018, 05:04 PM |
| Bozigian Haig P. | Chief Development Officer | Nov 06, 2018 | Sale | $110.10 | 9,420 | 1,037,170 | 135,997 | Nov 08, 2018, 05:04 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Nov 07, 2018 | Option Exercise | $15.45 | 3,300 | 50,985 | 18,618 | Nov 08, 2018, 05:03 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Nov 06, 2018 | Option Exercise | $15.45 | 5,700 | 88,065 | 21,018 | Nov 08, 2018, 05:03 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Nov 07, 2018 | Sale | $110.00 | 3,300 | 363,000 | 15,318 | Nov 08, 2018, 05:03 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Nov 06, 2018 | Sale | $110.02 | 5,700 | 627,097 | 15,318 | Nov 08, 2018, 05:03 PM |
| LYONS GARY A | Director | Nov 02, 2018 | Sale | $114.41 | 15,000 | 1,716,210 | 245,697 | Nov 05, 2018, 04:11 PM |
| POPS RICHARD F | Director | Oct 29, 2018 | Sale | $107.13 | 5,500 | 589,237 | 37,759 | Oct 30, 2018, 05:58 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Sep 04, 2018 | Option Exercise | $12.21 | 32,749 | 399,977 | 115,691 | Sep 05, 2018, 08:41 PM |
| Gano Kyle | Chief Business Development Off | Aug 01, 2018 | Option Exercise | $8.66 | 28,266 | 244,784 | 107,008 | Aug 03, 2018, 04:08 PM |
| Gano Kyle | Chief Business Development Off | Aug 01, 2018 | Sale | $115.00 | 28,266 | 3,250,590 | 78,742 | Aug 03, 2018, 04:08 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Aug 01, 2018 | Option Exercise | $19.59 | 23,022 | 451,001 | 105,964 | Aug 03, 2018, 04:07 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Aug 01, 2018 | Sale | $110.00 | 23,022 | 2,532,420 | 82,942 | Aug 03, 2018, 04:07 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jun 28, 2018 | Option Exercise | $9.21 | 57,924 | 533,416 | 404,957 | Jun 29, 2018, 07:32 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 20, 2018 | Option Exercise | $19.59 | 23,000 | 450,570 | 105,942 | Jun 21, 2018, 06:16 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 20, 2018 | Sale | $105.00 | 23,000 | 2,415,000 | 82,942 | Jun 21, 2018, 06:16 PM |
| LYONS GARY A | Director | Jun 13, 2018 | Sale | $99.24 | 15,000 | 1,488,549 | 260,697 | Jun 15, 2018, 04:45 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 14, 2018 | Option Exercise | $19.59 | 2,785 | 54,558 | 85,727 | Jun 15, 2018, 04:44 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 13, 2018 | Option Exercise | $11.28 | 84,178 | 949,292 | 146,905 | Jun 15, 2018, 04:44 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 14, 2018 | Sale | $100.00 | 2,785 | 278,500 | 82,942 | Jun 15, 2018, 04:44 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 13, 2018 | Sale | $99.46 | 84,178 | 8,372,246 | 82,942 | Jun 15, 2018, 04:44 PM |
| SHERWIN STEPHEN A | Director | Jun 11, 2018 | Sale | $98.44 | 10,000 | 984,420 | 47,548 | Jun 13, 2018, 12:34 PM |
| BENEVICH ERIC | Chief Commercial Officer | Jun 01, 2018 | Sale | $97.34 | 12,350 | 1,202,164 | 16,690 | Jun 05, 2018, 06:53 PM |
| Nevinny Corinne H | Director | May 07, 2018 | Sale | $83.13 | 5,000 | 415,625 | 43,283 | May 09, 2018, 06:12 PM |
| Nevinny Corinne H | Director | May 02, 2018 | Option Exercise | $80.08 | 1,320 | 105,706 | 48,283 | May 03, 2018, 07:53 PM |
| Nevinny Corinne H | Director | May 02, 2018 | Option Exercise | $7.05 | 15,000 | 105,750 | 49,603 | May 03, 2018, 07:53 PM |
| POPS RICHARD F | Director | May 01, 2018 | Option Exercise | $84.39 | 1,253 | 105,741 | 43,259 | May 03, 2018, 07:42 PM |
| POPS RICHARD F | Director | May 01, 2018 | Option Exercise | $7.05 | 15,000 | 105,750 | 44,512 | May 03, 2018, 07:42 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | May 01, 2018 | Option Exercise | $5.76 | 126,832 | 730,552 | 473,865 | May 03, 2018, 07:39 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | May 01, 2018 | Sale | $80.75 | 126,832 | 10,241,734 | 347,033 | May 03, 2018, 07:39 PM |
| SHERWIN STEPHEN A | Director | Apr 26, 2018 | Option Exercise | $79.44 | 1,331 | 105,735 | 57,548 | Apr 30, 2018, 04:03 PM |
| SHERWIN STEPHEN A | Director | Apr 26, 2018 | Option Exercise | $7.05 | 15,000 | 105,750 | 58,879 | Apr 30, 2018, 04:03 PM |
| LYONS GARY A | Director | Apr 03, 2018 | Option Exercise | $77.23 | 1,369 | 105,728 | 275,697 | Apr 05, 2018, 06:52 PM |
| LYONS GARY A | Director | Apr 03, 2018 | Option Exercise | $7.05 | 15,000 | 105,750 | 277,066 | Apr 05, 2018, 06:52 PM |
| Lippoldt Darin | Chief Legal Officer | Mar 05, 2018 | Option Exercise | $18.15 | 1,979 | 35,919 | 18,041 | Mar 07, 2018, 04:18 PM |
| Lippoldt Darin | Chief Legal Officer | Mar 05, 2018 | Sale | $88.47 | 1,979 | 175,090 | 16,062 | Mar 07, 2018, 04:18 PM |
| Gano Kyle | Chief Business Development Off | Mar 05, 2018 | Option Exercise | $8.65 | 23,650 | 204,572 | 102,392 | Mar 07, 2018, 04:16 PM |
| Gano Kyle | Chief Business Development Off | Mar 05, 2018 | Sale | $90.00 | 23,650 | 2,128,500 | 78,742 | Mar 07, 2018, 04:16 PM |
| Bozigian Haig P. | Chief Development Officer | Mar 05, 2018 | Option Exercise | $12.87 | 75,873 | 976,703 | 197,471 | Mar 07, 2018, 04:13 PM |
| Bozigian Haig P. | Chief Development Officer | Mar 05, 2018 | Sale | $90.00 | 75,873 | 6,828,570 | 135,997 | Mar 07, 2018, 04:13 PM |
| LYONS GARY A | Director | Feb 15, 2018 | Sale | $84.67 | 5,000 | 423,341 | 262,066 | Feb 20, 2018, 04:02 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 12, 2018 | Option Exercise | $8.66 | 14,593 | 126,375 | 97,535 | Feb 13, 2018, 04:12 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 09, 2018 | Option Exercise | $8.66 | 71,775 | 621,571 | 154,717 | Feb 13, 2018, 04:12 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 12, 2018 | Sale | $80.00 | 14,593 | 1,167,453 | 82,942 | Feb 13, 2018, 04:12 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 09, 2018 | Sale | $77.98 | 71,775 | 5,596,720 | 82,942 | Feb 13, 2018, 04:12 PM |
| OBrien Christopher Flint | Former Chief Medical Officer | Feb 06, 2018 | Option Exercise | $82.48 | 1,014 | 83,635 | 55,946 | Feb 07, 2018, 06:08 PM |
| OBrien Christopher Flint | Former Chief Medical Officer | Feb 05, 2018 | Sale | $83.18 | 2,613 | 217,341 | 54,310 | Feb 07, 2018, 06:08 PM |
| LYONS GARY A | Director | Feb 05, 2018 | Sale | $83.08 | 5,000 | 415,380 | 267,066 | Feb 07, 2018, 06:08 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 06, 2018 | Option Exercise | $82.48 | 1,314 | 108,379 | 15,318 | Feb 07, 2018, 06:07 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 05, 2018 | Sale | $83.19 | 960 | 79,863 | 13,982 | Feb 07, 2018, 06:07 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 06, 2018 | Option Exercise | $82.48 | 787 | 64,912 | 16,062 | Feb 07, 2018, 06:07 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 05, 2018 | Option Exercise | $18.15 | 1,979 | 35,919 | 15,136 | Feb 07, 2018, 06:07 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 05, 2018 | Sale | $83.12 | 2,737 | 227,494 | 14,574 | Feb 07, 2018, 06:07 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 06, 2018 | Option Exercise | $82.48 | 528 | 43,549 | 82,942 | Feb 07, 2018, 06:06 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 05, 2018 | Sale | $83.09 | 2,046 | 169,997 | 81,945 | Feb 07, 2018, 06:06 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 06, 2018 | Option Exercise | $82.48 | 4,091 | 337,426 | 347,033 | Feb 07, 2018, 06:06 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 06, 2018 | Option Exercise | $5.76 | 100,000 | 576,000 | 442,874 | Feb 07, 2018, 06:06 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 05, 2018 | Sale | $83.26 | 5,983 | 498,164 | 342,874 | Feb 07, 2018, 06:06 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 06, 2018 | Sale | $80.07 | 100,000 | 8,006,620 | 342,874 | Feb 07, 2018, 06:06 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 06, 2018 | Option Exercise | $82.48 | 917 | 75,634 | 135,997 | Feb 07, 2018, 06:05 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 05, 2018 | Sale | $83.10 | 2,262 | 187,977 | 134,264 | Feb 07, 2018, 06:05 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 06, 2018 | Option Exercise | $82.48 | 917 | 75,634 | 4,310 | Feb 07, 2018, 06:00 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 05, 2018 | Sale | $83.14 | 820 | 68,174 | 2,577 | Feb 07, 2018, 06:00 PM |
| Gano Kyle | Chief Business Development Off | Feb 06, 2018 | Option Exercise | $82.48 | 658 | 54,272 | 79,446 | Feb 07, 2018, 05:59 PM |
| Gano Kyle | Chief Business Development Off | Feb 05, 2018 | Sale | $83.05 | 2,046 | 169,914 | 78,204 | Feb 07, 2018, 05:59 PM |
| RASTETTER WILLIAM H | Director | Jan 24, 2018 | Option Exercise | $7.05 | 20,000 | 141,000 | 34,250 | Jan 26, 2018, 04:04 PM |
| RASTETTER WILLIAM H | Director | Jan 24, 2018 | Sale | $90.00 | 9,500 | 855,000 | 24,750 | Jan 26, 2018, 04:04 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 16, 2018 | Sale | $79.14 | 1,750 | 138,499 | 50,723 | Jan 18, 2018, 04:12 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 16, 2018 | Sale | $79.12 | 1,625 | 128,563 | 79,316 | Jan 18, 2018, 04:10 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 16, 2018 | Sale | $78.89 | 3,750 | 295,820 | 336,357 | Jan 18, 2018, 04:09 PM |
| Gano Kyle | Chief Business Development Off | Jan 16, 2018 | Sale | $79.05 | 1,625 | 128,460 | 74,871 | Jan 18, 2018, 04:08 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 16, 2018 | Sale | $79.12 | 1,625 | 128,575 | 131,226 | Jan 18, 2018, 04:07 PM |
| Lippoldt Darin | Chief Legal Officer | Jan 03, 2018 | Option Exercise | $18.15 | 1,979 | 35,919 | 15,136 | Jan 04, 2018, 04:07 PM |
| Lippoldt Darin | Chief Legal Officer | Jan 03, 2018 | Sale | $79.36 | 1,979 | 157,053 | 13,157 | Jan 04, 2018, 04:07 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Jan 02, 2018 | Option Exercise | $15.45 | 18,084 | 279,398 | 31,101 | Jan 04, 2018, 04:05 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Jan 02, 2018 | Sale | $77.52 | 18,084 | 1,401,823 | 13,017 | Jan 04, 2018, 04:05 PM |
| Lippoldt Darin | Chief Legal Officer | Dec 28, 2017 | Option Exercise | $18.15 | 15,237 | 276,552 | 28,394 | Jan 02, 2018, 04:02 PM |
| Lippoldt Darin | Chief Legal Officer | Dec 28, 2017 | Sale | $75.00 | 15,237 | 1,142,775 | 13,157 | Jan 02, 2018, 04:02 PM |
| Lippoldt Darin | Chief Legal Officer | Dec 08, 2017 | Option Exercise | $18.15 | 2,955 | 53,633 | 16,112 | Dec 11, 2017, 04:48 PM |
| Lippoldt Darin | Chief Legal Officer | Dec 08, 2017 | Sale | $75.00 | 2,955 | 221,625 | 13,157 | Dec 11, 2017, 04:48 PM |
| Lippoldt Darin | Chief Legal Officer | Dec 04, 2017 | Option Exercise | $18.15 | 6,279 | 113,964 | 19,436 | Dec 06, 2017, 04:59 PM |
| Lippoldt Darin | Chief Legal Officer | Dec 04, 2017 | Sale | $75.04 | 6,279 | 471,160 | 13,157 | Dec 06, 2017, 04:59 PM |
| LYONS GARY A | Director | Dec 01, 2017 | Sale | $72.92 | 10,000 | 729,182 | 272,066 | Dec 05, 2017, 04:31 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 15, 2017 | Option Exercise | $18.15 | 9,900 | 179,685 | 23,057 | Nov 17, 2017, 04:29 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 15, 2017 | Sale | $73.05 | 9,900 | 723,191 | 13,157 | Nov 17, 2017, 04:29 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Nov 08, 2017 | Sale | $74.58 | 30,000 | 2,237,343 | 77,691 | Nov 13, 2017, 04:15 PM |
| OBrien Christopher Flint | Chief Medical Officer | Nov 02, 2017 | Option Exercise | $8.66 | 52,817 | 457,320 | 94,272 | Nov 06, 2017, 04:45 PM |
| OBrien Christopher Flint | Chief Medical Officer | Nov 02, 2017 | Sale | $69.71 | 52,817 | 3,681,641 | 48,973 | Nov 06, 2017, 04:45 PM |
| Gano Kyle | Chief Business Development Off | Nov 02, 2017 | Option Exercise | $8.66 | 24,818 | 214,810 | 86,714 | Nov 06, 2017, 04:44 PM |
| Gano Kyle | Chief Business Development Off | Nov 02, 2017 | Sale | $71.05 | 24,818 | 1,763,319 | 73,246 | Nov 06, 2017, 04:44 PM |
| OBrien Christopher Flint | Chief Medical Officer | Oct 02, 2017 | Option Exercise | $8.65 | 6,925 | 59,901 | 55,898 | Oct 03, 2017, 07:14 PM |
| OBrien Christopher Flint | Chief Medical Officer | Oct 02, 2017 | Sale | $61.04 | 6,925 | 422,702 | 48,973 | Oct 03, 2017, 07:14 PM |
| Gano Kyle | Chief Business Development Off | Sep 06, 2017 | Option Exercise | $8.65 | 20,393 | 176,399 | 93,639 | Oct 03, 2017, 07:13 PM |
| Gano Kyle | Chief Business Development Off | Sep 06, 2017 | Sale | $60.00 | 20,393 | 1,223,580 | 73,246 | Oct 03, 2017, 07:13 PM |
| Lippoldt Darin | Chief Legal Officer | Sep 06, 2017 | Option Exercise | $18.15 | 100 | 1,815 | 13,257 | Sep 08, 2017, 02:59 PM |
| Lippoldt Darin | Chief Legal Officer | Sep 06, 2017 | Sale | $60.00 | 100 | 6,000 | 13,157 | Sep 08, 2017, 02:59 PM |
| Gano Kyle | Chief Business Development Off | Sep 06, 2017 | Option Exercise | $8.65 | 4,607 | 39,851 | 77,853 | Sep 08, 2017, 02:58 PM |
| Gano Kyle | Chief Business Development Off | Sep 06, 2017 | Sale | $60.00 | 4,607 | 276,420 | 73,246 | Sep 08, 2017, 02:58 PM |
| Bozigian Haig P. | Chief Development Officer | Sep 06, 2017 | Option Exercise | $13.34 | 26,250 | 350,137 | 144,601 | Sep 08, 2017, 02:58 PM |
| Bozigian Haig P. | Chief Development Officer | Sep 06, 2017 | Sale | $60.00 | 26,250 | 1,575,000 | 129,601 | Sep 08, 2017, 02:58 PM |
| OBrien Christopher Flint | Chief Medical Officer | Sep 05, 2017 | Option Exercise | $8.66 | 52,817 | 457,395 | 101,790 | Sep 07, 2017, 05:55 PM |
| OBrien Christopher Flint | Chief Medical Officer | Sep 05, 2017 | Sale | $57.50 | 52,817 | 3,036,978 | 48,973 | Sep 07, 2017, 05:55 PM |
| Lippoldt Darin | Chief Legal Officer | Aug 09, 2017 | Option Exercise | $18.15 | 5,000 | 90,750 | 18,157 | Aug 14, 2017, 12:30 PM |
| Lippoldt Darin | Chief Legal Officer | Aug 09, 2017 | Sale | $55.00 | 5,000 | 275,000 | 13,157 | Aug 14, 2017, 12:30 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Aug 09, 2017 | Option Exercise | $5.76 | 15,354 | 88,439 | 123,045 | Aug 14, 2017, 12:29 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Aug 09, 2017 | Sale | $55.00 | 15,354 | 844,470 | 107,691 | Aug 14, 2017, 12:29 PM |
| Bozigian Haig P. | Chief Development Officer | Aug 04, 2017 | Option Exercise | $7.05 | 45,000 | 317,200 | 154,601 | Aug 08, 2017, 05:44 PM |
| Bozigian Haig P. | Chief Development Officer | Aug 04, 2017 | Sale | $50.00 | 22,500 | 1,125,000 | 129,601 | Aug 08, 2017, 05:44 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jul 27, 2017 | Option Exercise | $8.65 | 8,734 | 75,549 | 57,707 | Jul 31, 2017, 04:29 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jul 27, 2017 | Sale | $50.00 | 8,734 | 436,700 | 48,973 | Jul 31, 2017, 04:29 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | May 23, 2017 | Sale | $53.39 | 10,000 | 533,900 | 107,691 | May 24, 2017, 04:13 PM |
| OBrien Christopher Flint | Chief Medical Officer | May 18, 2017 | Option Exercise | $6.36 | 105,634 | 671,915 | 154,607 | May 23, 2017, 04:36 PM |
| OBrien Christopher Flint | Chief Medical Officer | May 18, 2017 | Sale | $53.32 | 105,634 | 5,632,405 | 48,973 | May 23, 2017, 04:36 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | May 19, 2017 | Option Exercise | $15.45 | 4,980 | 76,941 | 17,997 | May 23, 2017, 04:34 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | May 18, 2017 | Option Exercise | $15.45 | 4,980 | 76,941 | 17,997 | May 23, 2017, 04:34 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | May 18, 2017 | Sale | $53.26 | 4,980 | 265,235 | 13,017 | May 23, 2017, 04:34 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | May 19, 2017 | Sale | $54.00 | 4,980 | 268,920 | 13,017 | May 23, 2017, 04:34 PM |
| Lippoldt Darin | Chief Legal Officer | May 18, 2017 | Option Exercise | $18.15 | 10,000 | 181,500 | 23,157 | May 23, 2017, 04:34 PM |
| Lippoldt Darin | Chief Legal Officer | May 18, 2017 | Sale | $53.27 | 10,000 | 532,700 | 13,157 | May 23, 2017, 04:34 PM |
| Nevinny Corinne H | Director | May 05, 2017 | Sale | $53.98 | 5,000 | 269,900 | 34,603 | May 08, 2017, 08:22 PM |
| POPS RICHARD F | Director | May 03, 2017 | Option Exercise | $53.37 | 952 | 50,808 | 29,512 | May 05, 2017, 01:27 PM |
| POPS RICHARD F | Director | May 03, 2017 | Option Exercise | $3.40 | 15,000 | 51,000 | 30,454 | May 05, 2017, 01:27 PM |
| Nevinny Corinne H | Director | May 03, 2017 | Option Exercise | $53.37 | 952 | 50,808 | 39,603 | May 05, 2017, 01:26 PM |
| Nevinny Corinne H | Director | May 03, 2017 | Option Exercise | $3.40 | 15,000 | 51,000 | 40,555 | May 05, 2017, 01:26 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | May 02, 2017 | Sale | $55.00 | 10,000 | 550,000 | 117,691 | May 03, 2017, 06:43 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | May 02, 2017 | Option Exercise | $2.59 | 21,739 | 56,304 | 354,346 | May 03, 2017, 06:42 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | May 02, 2017 | Sale | $53.23 | 21,739 | 1,157,167 | 332,607 | May 03, 2017, 06:42 PM |
| Gano Kyle | Chief Business Development Off | May 01, 2017 | Option Exercise | $2.59 | 15,000 | 38,850 | 88,246 | May 03, 2017, 06:41 PM |
| Gano Kyle | Chief Business Development Off | May 01, 2017 | Sale | $54.00 | 15,000 | 810,000 | 73,246 | May 03, 2017, 06:41 PM |
| MOLLICA JOSEPH A | Director | Apr 12, 2017 | Option Exercise | $51.80 | 1,312 | 67,962 | 56,042 | Apr 13, 2017, 05:32 PM |
| MOLLICA JOSEPH A | Director | Apr 12, 2017 | Option Exercise | $3.40 | 20,000 | 68,000 | 57,354 | Apr 13, 2017, 05:32 PM |
| OBrien Christopher Flint | Chief Medical Officer | Apr 12, 2017 | Sale | $50.42 | 13,065 | 658,774 | 49,177 | Apr 13, 2017, 04:56 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Apr 12, 2017 | Sale | $50.42 | 13,065 | 658,774 | 13,221 | Apr 13, 2017, 04:56 PM |
| Lippoldt Darin | Chief Legal Officer | Apr 12, 2017 | Sale | $50.42 | 13,065 | 658,774 | 13,361 | Apr 13, 2017, 04:55 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Apr 12, 2017 | Sale | $50.42 | 13,065 | 658,774 | 127,895 | Apr 13, 2017, 04:54 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Apr 12, 2017 | Sale | $50.42 | 19,596 | 988,085 | 332,913 | Apr 13, 2017, 04:53 PM |
| Gano Kyle | Chief Business Development Off | Apr 12, 2017 | Sale | $50.42 | 13,065 | 658,774 | 73,450 | Apr 13, 2017, 04:53 PM |
| Bozigian Haig P. | Chief Development Officer | Apr 12, 2017 | Sale | $50.42 | 13,065 | 658,774 | 129,805 | Apr 13, 2017, 04:52 PM |
| LYONS GARY A | Director | Feb 14, 2017 | Option Exercise | $3.40 | 15,000 | 51,000 | 282,066 | Feb 15, 2017, 06:52 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 06, 2017 | Sale | $43.13 | 727 | 31,356 | 115,756 | Feb 08, 2017, 07:44 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 06, 2017 | Sale | $43.14 | 963 | 41,544 | 117,666 | Feb 08, 2017, 07:43 PM |
| Gano Kyle | Chief Business Development Off | Feb 06, 2017 | Sale | $43.15 | 727 | 31,370 | 61,311 | Feb 08, 2017, 07:42 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 07, 2017 | Sale | $44.61 | 116 | 5,175 | 1,082 | Feb 08, 2017, 07:41 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Feb 06, 2017 | Sale | $43.15 | 727 | 31,370 | 0 | Feb 08, 2017, 07:41 PM |
| OBrien Christopher Flint | Chief Medical Officer | Feb 06, 2017 | Sale | $43.17 | 1,206 | 52,063 | 37,038 | Feb 08, 2017, 07:40 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 07, 2017 | Sale | $44.65 | 132 | 5,894 | 1,222 | Feb 08, 2017, 07:40 PM |
| BENEVICH ERIC | Chief Commercial Officer | Feb 06, 2017 | Sale | $43.11 | 821 | 35,393 | 0 | Feb 08, 2017, 07:40 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 07, 2017 | Sale | $44.62 | 132 | 5,890 | 1,222 | Feb 08, 2017, 07:39 PM |
| Lippoldt Darin | Chief Legal Officer | Feb 06, 2017 | Sale | $43.13 | 821 | 35,410 | 0 | Feb 08, 2017, 07:39 PM |
| Coughlin Timothy P | Chief Financial Officer | Feb 06, 2017 | Sale | $43.14 | 963 | 41,544 | 137,961 | Feb 08, 2017, 07:39 PM |
| SHERWIN STEPHEN A | Director | Feb 07, 2017 | Option Exercise | $43.60 | 1,169 | 50,968 | 43,879 | Feb 08, 2017, 07:38 PM |
| SHERWIN STEPHEN A | Director | Feb 07, 2017 | Option Exercise | $3.40 | 15,000 | 51,000 | 45,048 | Feb 08, 2017, 07:38 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 08, 2017 | Option Exercise | $2.59 | 64,161 | 166,177 | 314,703 | Feb 08, 2017, 07:37 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 06, 2017 | Sale | $43.18 | 3,010 | 129,972 | 250,542 | Feb 08, 2017, 07:37 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 03, 2017 | Sale | $42.57 | 1,375 | 58,534 | 116,079 | Feb 06, 2017, 07:19 PM |
| Coughlin Timothy P | Chief Financial Officer | Feb 03, 2017 | Sale | $42.55 | 1,500 | 63,825 | 136,324 | Feb 06, 2017, 07:19 PM |
| Gano Kyle | Chief Business Development Off | Feb 03, 2017 | Sale | $42.57 | 1,375 | 58,534 | 60,113 | Feb 06, 2017, 07:18 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Feb 03, 2017 | Sale | $42.55 | 3,125 | 132,969 | 247,802 | Feb 06, 2017, 07:18 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 03, 2017 | Sale | $42.56 | 1,375 | 58,520 | 114,558 | Feb 06, 2017, 07:17 PM |
| OBrien Christopher Flint | Chief Medical Officer | Feb 03, 2017 | Sale | $42.50 | 1,500 | 63,750 | 35,044 | Feb 06, 2017, 07:16 PM |
| RASTETTER WILLIAM H | Director | Feb 01, 2017 | Option Exercise | $2.17 | 25,000 | 54,250 | 25,000 | Feb 02, 2017, 07:29 PM |
| RASTETTER WILLIAM H | Director | Feb 01, 2017 | Sale | $42.28 | 10,750 | 454,510 | 14,250 | Feb 02, 2017, 07:29 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 17, 2017 | Sale | $40.63 | 1,625 | 66,024 | 114,704 | Jan 18, 2017, 06:45 PM |
| Coughlin Timothy P | Chief Financial Officer | Jan 17, 2017 | Sale | $40.65 | 1,750 | 71,138 | 134,824 | Jan 18, 2017, 06:45 PM |
| Gano Kyle | Chief Business Development Off | Jan 17, 2017 | Sale | $40.65 | 1,625 | 66,056 | 58,738 | Jan 18, 2017, 06:44 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 17, 2017 | Sale | $40.65 | 3,750 | 152,438 | 244,677 | Jan 18, 2017, 06:43 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 17, 2017 | Sale | $40.63 | 1,625 | 66,024 | 113,183 | Jan 18, 2017, 06:41 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 17, 2017 | Sale | $40.66 | 1,750 | 71,155 | 33,544 | Jan 18, 2017, 06:41 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 10, 2017 | Sale | $43.35 | 1,750 | 75,862 | 31,794 | Jan 12, 2017, 07:02 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 10, 2017 | Sale | $43.39 | 1,625 | 70,509 | 111,558 | Jan 12, 2017, 07:02 PM |
| GORMAN KEVIN CHARLES | Chief Executive Officer | Jan 10, 2017 | Sale | $43.28 | 3,750 | 162,300 | 240,927 | Jan 12, 2017, 07:01 PM |
| Gano Kyle | Chief Business Development Off | Jan 10, 2017 | Sale | $43.37 | 1,250 | 54,212 | 57,113 | Jan 12, 2017, 07:00 PM |
| Coughlin Timothy P | Chief Financial Officer | Jan 10, 2017 | Sale | $43.37 | 1,750 | 75,897 | 133,124 | Jan 12, 2017, 06:59 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 10, 2017 | Sale | $43.37 | 1,625 | 70,476 | 113,079 | Jan 12, 2017, 06:59 PM |
| GORMAN KEVIN CHARLES | President and CEO | Dec 23, 2016 | Option Exercise | $2.59 | 9,100 | 23,569 | 237,177 | Dec 23, 2016, 03:44 PM |
| OBrien Christopher Flint | Chief Medical Officer | Nov 15, 2016 | Sale | $52.84 | 25,000 | 1,321,000 | 30,044 | Nov 16, 2016, 03:52 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Sep 01, 2016 | Option Exercise | $15.45 | 9,000 | 139,050 | 9,000 | Sep 02, 2016, 03:26 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | Sep 01, 2016 | Sale | $50.00 | 9,000 | 450,000 | 0 | Sep 02, 2016, 03:26 PM |
| OBrien Christopher Flint | Chief Medical Officer | Aug 15, 2016 | Sale | $48.73 | 12,500 | 609,125 | 55,044 | Aug 16, 2016, 06:46 PM |
| Nevinny Corinne H | Director | Aug 08, 2016 | Sale | $48.54 | 5,000 | 242,700 | 25,555 | Aug 09, 2016, 06:05 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | May 31, 2016 | Option Exercise | $15.45 | 9,000 | 139,050 | 9,000 | Jun 02, 2016, 04:03 PM |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | May 31, 2016 | Sale | $50.00 | 9,000 | 450,000 | 0 | Jun 02, 2016, 04:03 PM |
| OBrien Christopher Flint | Chief Medical Officer | May 31, 2016 | Sale | $50.00 | 12,500 | 625,000 | 67,544 | Jun 02, 2016, 04:02 PM |
| POPS RICHARD F | Director | May 25, 2016 | Sale | $46.72 | 15,000 | 700,800 | 15,464 | May 26, 2016, 07:03 PM |
| OBrien Christopher Flint | Chief Medical Officer | May 16, 2016 | Sale | $45.00 | 25,000 | 1,125,000 | 80,044 | May 18, 2016, 07:54 PM |
| POPS RICHARD F | Director | May 16, 2016 | Option Exercise | $45.64 | 1,008 | 46,005 | 30,464 | May 18, 2016, 07:53 PM |
| POPS RICHARD F | Director | May 16, 2016 | Option Exercise | $3.07 | 15,000 | 46,050 | 31,472 | May 18, 2016, 07:53 PM |
| LYONS GARY A | Director | May 06, 2016 | Option Exercise | $3.07 | 15,000 | 46,050 | 267,066 | May 10, 2016, 06:09 PM |
| Nevinny Corinne H | Director | May 03, 2016 | Option Exercise | $45.05 | 1,022 | 46,041 | 30,555 | May 05, 2016, 03:42 PM |
| Nevinny Corinne H | Director | May 03, 2016 | Option Exercise | $3.07 | 15,000 | 46,050 | 31,577 | May 05, 2016, 03:42 PM |
| SHERWIN STEPHEN A | Director | Apr 14, 2016 | Option Exercise | $46.86 | 982 | 46,017 | 30,048 | Apr 18, 2016, 06:02 PM |
| SHERWIN STEPHEN A | Director | Apr 14, 2016 | Option Exercise | $3.07 | 15,000 | 46,050 | 31,030 | Apr 18, 2016, 06:02 PM |
| Gano Kyle | Chief Business Development Off | Apr 11, 2016 | Option Exercise | $5.76 | 41,770 | 240,595 | 97,633 | Apr 13, 2016, 08:46 PM |
| Gano Kyle | Chief Business Development Off | Apr 11, 2016 | Sale | $44.02 | 41,770 | 1,838,511 | 95,708 | Apr 13, 2016, 08:46 PM |
| OBrien Christopher Flint | Chief Medical Officer | Apr 06, 2016 | Sale | $45.00 | 25,000 | 1,125,000 | 105,044 | Apr 08, 2016, 05:27 PM |
| MOLLICA JOSEPH A | Director | Feb 10, 2016 | Option Exercise | $33.70 | 1,821 | 61,368 | 37,354 | Feb 12, 2016, 03:47 PM |
| MOLLICA JOSEPH A | Director | Feb 10, 2016 | Option Exercise | $3.07 | 20,000 | 61,400 | 39,175 | Feb 12, 2016, 03:47 PM |
| OBrien Christopher Flint | Chief Medical Officer | Feb 03, 2016 | Sale | $38.01 | 1,500 | 57,015 | 130,044 | Feb 04, 2016, 07:25 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 03, 2016 | Sale | $37.98 | 1,375 | 52,222 | 109,933 | Feb 04, 2016, 07:24 PM |
| GORMAN KEVIN CHARLES | President and CEO | Feb 03, 2016 | Sale | $38.04 | 3,125 | 118,875 | 228,077 | Feb 04, 2016, 07:24 PM |
| Gano Kyle | Chief Business Development Off | Feb 03, 2016 | Sale | $37.98 | 1,375 | 52,222 | 55,863 | Feb 04, 2016, 07:23 PM |
| Coughlin Timothy P | Chief Financial Officer | Feb 03, 2016 | Sale | $38.06 | 1,500 | 57,090 | 131,374 | Feb 04, 2016, 07:23 PM |
| Bozigian Haig P. | Chief Development Officer | Feb 03, 2016 | Sale | $38.13 | 1,375 | 52,429 | 111,454 | Feb 04, 2016, 07:22 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 19, 2016 | Sale | $46.77 | 1,750 | 81,848 | 128,544 | Jan 21, 2016, 04:14 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 19, 2016 | Sale | $46.76 | 1,625 | 75,985 | 108,558 | Jan 21, 2016, 04:14 PM |
| GORMAN KEVIN CHARLES | President and CEO | Jan 19, 2016 | Sale | $46.70 | 3,750 | 175,125 | 224,952 | Jan 21, 2016, 04:13 PM |
| Gano Kyle | Chief Business Development Off | Jan 19, 2016 | Sale | $46.84 | 1,625 | 76,115 | 54,488 | Jan 21, 2016, 04:13 PM |
| Coughlin Timothy P | Chief Financial Officer | Jan 19, 2016 | Sale | $46.69 | 1,750 | 81,707 | 129,874 | Jan 21, 2016, 04:13 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 19, 2016 | Sale | $46.77 | 1,625 | 76,001 | 110,079 | Jan 21, 2016, 04:12 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 11, 2016 | Sale | $44.25 | 1,750 | 77,438 | 126,794 | Jan 13, 2016, 06:20 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 11, 2016 | Sale | $44.21 | 1,625 | 71,841 | 106,933 | Jan 13, 2016, 06:20 PM |
| GORMAN KEVIN CHARLES | President and CEO | Jan 11, 2016 | Sale | $44.17 | 3,750 | 165,637 | 221,202 | Jan 13, 2016, 06:19 PM |
| Gano Kyle | Chief Business Development Off | Jan 11, 2016 | Sale | $44.23 | 1,250 | 55,287 | 52,863 | Jan 13, 2016, 06:18 PM |
| Coughlin Timothy P | Chief Financial Officer | Jan 11, 2016 | Sale | $44.25 | 1,750 | 77,438 | 128,124 | Jan 13, 2016, 06:17 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 11, 2016 | Sale | $44.25 | 1,625 | 71,906 | 108,454 | Jan 13, 2016, 06:17 PM |
| SHERWIN STEPHEN A | Director | Apr 07, 2015 | Option Exercise | $40.20 | 1,776 | 71,395 | 16,030 | Jan 12, 2016, 06:06 PM |
| SHERWIN STEPHEN A | Director | Apr 07, 2015 | Option Exercise | $4.76 | 15,000 | 71,400 | 17,806 | Jan 12, 2016, 06:06 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Nov 27, 2015 | Option Exercise | $5.76 | 10,000 | 57,600 | 115,308 | Dec 01, 2015, 03:48 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Nov 27, 2015 | Sale | $57.50 | 10,000 | 575,000 | 105,308 | Dec 01, 2015, 03:48 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 09, 2015 | Option Exercise | $18.15 | 23,761 | 431,262 | 23,761 | Nov 10, 2015, 05:23 PM |
| Lippoldt Darin | Chief Legal Officer | Nov 09, 2015 | Sale | $52.92 | 23,761 | 1,257,432 | 0 | Nov 10, 2015, 05:23 PM |
| OBrien Christopher Flint | Chief Medical Officer | Oct 16, 2015 | Sale | $47.78 | 25,000 | 1,194,500 | 125,044 | Oct 19, 2015, 07:59 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Oct 16, 2015 | Sale | $47.77 | 25,000 | 1,194,250 | 105,308 | Oct 19, 2015, 07:58 PM |
| GORMAN KEVIN CHARLES | President and CEO | Oct 16, 2015 | Sale | $47.77 | 33,500 | 1,600,295 | 217,452 | Oct 19, 2015, 07:58 PM |
| Gano Kyle | Chief Business Development Off | Oct 16, 2015 | Sale | $47.77 | 25,000 | 1,194,250 | 51,613 | Oct 19, 2015, 07:57 PM |
| Coughlin Timothy P | Chief Financial Officer | Oct 16, 2015 | Sale | $47.78 | 25,000 | 1,194,500 | 126,374 | Oct 19, 2015, 07:57 PM |
| Bozigian Haig P. | Chief Development Officer | Oct 16, 2015 | Sale | $47.78 | 25,000 | 1,194,500 | 106,829 | Oct 19, 2015, 07:56 PM |
| LYONS GARY A | Director | Sep 18, 2015 | Sale | $54.89 | 15,000 | 823,300 | 257,066 | Sep 21, 2015, 07:31 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jul 20, 2015 | Option Exercise | $5.76 | 11,250 | 64,800 | 111,294 | Jul 21, 2015, 08:11 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jul 20, 2015 | Sale | $55.00 | 11,250 | 618,750 | 100,044 | Jul 21, 2015, 08:11 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jul 20, 2015 | Option Exercise | $5.76 | 19,646 | 113,161 | 99,954 | Jul 21, 2015, 08:10 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jul 20, 2015 | Sale | $55.00 | 19,646 | 1,080,530 | 80,308 | Jul 21, 2015, 08:10 PM |
| Coughlin Timothy P | Chief Financial Officer | Jul 20, 2015 | Option Exercise | $5.76 | 20,000 | 115,200 | 121,374 | Jul 21, 2015, 08:09 PM |
| Coughlin Timothy P | Chief Financial Officer | Jul 20, 2015 | Sale | $55.00 | 20,000 | 1,100,000 | 101,374 | Jul 21, 2015, 08:09 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jul 13, 2015 | Option Exercise | $5.76 | 10,000 | 57,600 | 110,004 | Jul 14, 2015, 06:52 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jul 13, 2015 | Sale | $50.00 | 10,000 | 500,000 | 100,044 | Jul 14, 2015, 06:52 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jul 13, 2015 | Option Exercise | $5.76 | 10,000 | 57,600 | 90,308 | Jul 14, 2015, 06:51 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jul 13, 2015 | Sale | $50.00 | 10,000 | 500,000 | 80,308 | Jul 14, 2015, 06:51 PM |
| Coughlin Timothy P | Chief Financial Officer | Jul 13, 2015 | Option Exercise | $5.76 | 20,000 | 115,200 | 121,374 | Jul 14, 2015, 06:51 PM |
| Coughlin Timothy P | Chief Financial Officer | Jul 13, 2015 | Sale | $50.00 | 20,000 | 1,000,000 | 101,374 | Jul 14, 2015, 06:51 PM |
| MITCHELL W THOMAS | Director | Jun 23, 2015 | Option Exercise | $6.66 | 15,000 | 99,900 | 16,000 | Jun 24, 2015, 06:20 PM |
| MITCHELL W THOMAS | Director | Jun 23, 2015 | Sale | $49.35 | 15,000 | 740,250 | 1,000 | Jun 24, 2015, 06:20 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jun 08, 2015 | Option Exercise | $5.76 | 10,000 | 57,600 | 110,044 | Jun 10, 2015, 06:03 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jun 08, 2015 | Sale | $45.00 | 10,000 | 450,000 | 100,044 | Jun 10, 2015, 06:03 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 08, 2015 | Option Exercise | $5.76 | 10,000 | 57,600 | 90,308 | Jun 10, 2015, 06:01 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 08, 2015 | Sale | $45.00 | 10,000 | 450,000 | 80,308 | Jun 10, 2015, 06:01 PM |
| Coughlin Timothy P | Chief Financial Officer | Jun 08, 2015 | Option Exercise | $2.59 | 60,000 | 155,400 | 161,374 | Jun 10, 2015, 05:58 PM |
| Coughlin Timothy P | Chief Financial Officer | Jun 08, 2015 | Sale | $45.08 | 60,000 | 2,704,800 | 101,374 | Jun 10, 2015, 05:58 PM |
| Gano Kyle | See Remarks | Jun 01, 2015 | Option Exercise | $4.52 | 38,230 | 172,655 | 64,843 | Jun 03, 2015, 05:39 PM |
| Gano Kyle | See Remarks | Jun 01, 2015 | Sale | $42.19 | 38,230 | 1,612,924 | 26,613 | Jun 03, 2015, 05:39 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jun 01, 2015 | Option Exercise | $5.76 | 10,000 | 57,600 | 110,044 | Jun 03, 2015, 05:34 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jun 01, 2015 | Sale | $42.20 | 10,000 | 422,000 | 100,044 | Jun 03, 2015, 05:34 PM |
| POPS RICHARD F | Director | May 11, 2015 | Option Exercise | $39.63 | 1,801 | 71,374 | 16,472 | May 13, 2015, 03:02 PM |
| POPS RICHARD F | Director | May 11, 2015 | Option Exercise | $4.76 | 15,000 | 71,400 | 18,273 | May 13, 2015, 03:02 PM |
| Nevinny Corinne H | Director | Apr 08, 2015 | Option Exercise | $42.09 | 1,696 | 71,385 | 16,577 | Apr 10, 2015, 05:34 PM |
| Nevinny Corinne H | Director | Apr 08, 2015 | Option Exercise | $4.76 | 15,000 | 71,400 | 18,273 | Apr 10, 2015, 05:34 PM |
| NEUROCRINE BIOSCIENCES INC | Director | Apr 07, 2015 | Option Exercise | $40.20 | 1,776 | 71,395 | 16,030 | Apr 09, 2015, 04:22 PM |
| NEUROCRINE BIOSCIENCES INC | Director | Apr 07, 2015 | Option Exercise | $4.76 | 15,000 | 71,400 | 17,806 | Apr 09, 2015, 04:22 PM |
| Coughlin Timothy P | Chief Financial Officer | Mar 20, 2015 | Option Exercise | $2.59 | 40,000 | 103,600 | 141,374 | Mar 24, 2015, 06:23 PM |
| Coughlin Timothy P | Chief Financial Officer | Mar 20, 2015 | Sale | $44.49 | 40,000 | 1,779,600 | 101,374 | Mar 24, 2015, 06:23 PM |
| GORMAN KEVIN CHARLES | President and CEO | Mar 24, 2015 | Option Exercise | $2.59 | 40,000 | 103,600 | 228,452 | Mar 24, 2015, 06:21 PM |
| GORMAN KEVIN CHARLES | President and CEO | Mar 24, 2015 | Sale | $41.53 | 40,000 | 1,661,200 | 188,452 | Mar 24, 2015, 06:21 PM |
| LYONS GARY A | Director | Mar 24, 2015 | Sale | $41.53 | 30,000 | 1,245,900 | 267,066 | Mar 24, 2015, 06:21 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 23, 2015 | Option Exercise | $5.76 | 20,000 | 115,200 | 100,308 | Feb 25, 2015, 06:31 AM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 23, 2015 | Sale | $40.00 | 20,000 | 800,000 | 80,308 | Feb 25, 2015, 06:31 AM |
| LYONS GARY A | Director | Feb 10, 2015 | Option Exercise | $35.83 | 996 | 35,687 | 297,066 | Feb 11, 2015, 05:52 PM |
| LYONS GARY A | Director | Feb 10, 2015 | Option Exercise | $4.76 | 7,500 | 35,700 | 298,062 | Feb 11, 2015, 05:52 PM |
| LYONS GARY A | Director | Feb 10, 2015 | Option Exercise | $35.83 | 996 | 35,687 | 297,066 | Feb 11, 2015, 05:05 PM |
| LYONS GARY A | Director | Feb 10, 2015 | Option Exercise | $4.76 | 7,500 | 35,700 | 298,062 | Feb 11, 2015, 05:05 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 10, 2015 | Option Exercise | $5.76 | 20,000 | 115,200 | 100,308 | Feb 11, 2015, 05:02 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Feb 10, 2015 | Sale | $35.00 | 20,000 | 700,000 | 80,308 | Feb 11, 2015, 05:02 PM |
| LYONS GARY A | Director | Jan 20, 2015 | Option Exercise | $32.38 | 1,102 | 35,683 | 290,562 | Jan 22, 2015, 01:09 PM |
| LYONS GARY A | Director | Jan 20, 2015 | Option Exercise | $4.76 | 7,500 | 35,700 | 291,664 | Jan 22, 2015, 01:09 PM |
| GORMAN KEVIN CHARLES | President and CEO | Jan 16, 2015 | Sale | $30.79 | 3,750 | 115,463 | 188,452 | Jan 21, 2015, 02:45 PM |
| Coughlin Timothy P | Chief Financial Officer | Jan 16, 2015 | Sale | $30.81 | 1,750 | 53,917 | 101,374 | Jan 21, 2015, 02:42 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 16, 2015 | Sale | $30.79 | 1,750 | 53,883 | 100,044 | Jan 21, 2015, 02:40 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 16, 2015 | Sale | $30.77 | 1,625 | 50,001 | 80,308 | Jan 21, 2015, 02:36 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 16, 2015 | Sale | $30.79 | 1,625 | 50,034 | 81,829 | Jan 21, 2015, 02:34 PM |
| Gano Kyle | Chief Business Dev Officer | Jan 16, 2015 | Sale | $30.80 | 1,625 | 50,050 | 26,613 | Jan 21, 2015, 02:31 PM |
| Gano Kyle | Chief Business Dev Officer | Jan 13, 2015 | Option Exercise | $3.86 | 25,000 | 96,450 | 49,988 | Jan 15, 2015, 01:37 PM |
| Gano Kyle | Chief Business Dev Officer | Jan 13, 2015 | Sale | $30.00 | 25,000 | 750,000 | 24,988 | Jan 15, 2015, 01:37 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 13, 2015 | Option Exercise | $5.76 | 20,000 | 115,200 | 98,683 | Jan 15, 2015, 01:34 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 13, 2015 | Sale | $30.00 | 20,000 | 600,000 | 78,683 | Jan 15, 2015, 01:34 PM |
| MITCHELL W THOMAS | Director | Jan 13, 2015 | Option Exercise | $4.51 | 45,000 | 202,800 | 46,000 | Jan 15, 2015, 01:33 PM |
| MITCHELL W THOMAS | Director | Jan 13, 2015 | Sale | $30.07 | 45,000 | 1,353,150 | 1,000 | Jan 15, 2015, 01:33 PM |
| Coughlin Timothy P | Chief Financial Officer | Jan 12, 2015 | Sale | $28.37 | 1,750 | 49,648 | 99,624 | Jan 13, 2015, 06:02 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 12, 2015 | Sale | $28.45 | 1,625 | 46,231 | 80,204 | Jan 13, 2015, 05:54 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 12, 2015 | Sale | $28.41 | 1,750 | 49,717 | 98,294 | Jan 13, 2015, 05:53 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 12, 2015 | Sale | $28.38 | 1,625 | 46,117 | 78,683 | Jan 13, 2015, 05:50 PM |
| Gano Kyle | Chief Business Dev Officer | Jan 12, 2015 | Sale | $28.41 | 1,250 | 35,512 | 24,988 | Jan 13, 2015, 05:42 PM |
| GORMAN KEVIN CHARLES | President and CEO | Jan 12, 2015 | Sale | $28.43 | 3,750 | 106,613 | 184,702 | Jan 13, 2015, 05:41 PM |
| GORMAN KEVIN CHARLES | President and CEO | Jan 08, 2015 | Option Exercise | $2.59 | 25,000 | 64,750 | 205,952 | Jan 09, 2015, 04:45 PM |
| GORMAN KEVIN CHARLES | President and CEO | Jan 08, 2015 | Sale | $27.39 | 25,000 | 684,750 | 180,952 | Jan 09, 2015, 04:45 PM |
| Coughlin Timothy P | Chief Financial Officer | Jan 08, 2015 | Option Exercise | $2.59 | 10,000 | 25,900 | 107,874 | Jan 09, 2015, 04:37 PM |
| Coughlin Timothy P | Chief Financial Officer | Jan 08, 2015 | Sale | $27.25 | 10,000 | 272,500 | 97,874 | Jan 09, 2015, 04:37 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 08, 2015 | Option Exercise | $2.59 | 55,000 | 142,450 | 116,544 | Jan 09, 2015, 04:30 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 08, 2015 | Sale | $27.22 | 55,000 | 1,496,900 | 96,544 | Jan 09, 2015, 04:30 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 08, 2015 | Option Exercise | $2.59 | 30,000 | 77,700 | 98,579 | Jan 09, 2015, 04:27 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 08, 2015 | Sale | $27.24 | 30,000 | 817,200 | 78,579 | Jan 09, 2015, 04:27 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 08, 2015 | Option Exercise | $2.59 | 30,000 | 77,700 | 97,058 | Jan 09, 2015, 04:24 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 08, 2015 | Sale | $27.35 | 30,000 | 820,600 | 77,058 | Jan 09, 2015, 04:24 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 05, 2015 | Option Exercise | $5.12 | 2,500 | 12,800 | 81,079 | Jan 06, 2015, 05:35 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 05, 2015 | Sale | $22.76 | 2,500 | 56,900 | 78,579 | Jan 06, 2015, 05:35 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 05, 2015 | Option Exercise | $5.12 | 2,500 | 12,800 | 79,558 | Jan 06, 2015, 05:17 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 05, 2015 | Sale | $22.76 | 2,500 | 56,900 | 77,058 | Jan 06, 2015, 05:17 PM |
| MITCHELL W THOMAS | Director | Jan 02, 2015 | Option Exercise | $4.76 | 8,000 | 38,080 | 9,000 | Jan 06, 2015, 05:15 PM |
| MITCHELL W THOMAS | Director | Jan 02, 2015 | Sale | $22.79 | 8,000 | 182,320 | 1,000 | Jan 06, 2015, 05:15 PM |
| OBrien Christopher Flint | CHIEF MEDICAL OFFICER | Dec 19, 2014 | Option Exercise | $2.59 | 20,000 | 51,800 | 116,544 | Dec 19, 2014, 07:05 PM |
| OBrien Christopher Flint | CHIEF MEDICAL OFFICER | Dec 19, 2014 | Sale | $24.02 | 20,000 | 480,400 | 95,644 | Dec 19, 2014, 07:05 PM |
| GORMAN KEVIN CHARLES | PRESIDENT AND CEO | Dec 18, 2014 | Option Exercise | $4.22 | 70,000 | 295,150 | 210,952 | Dec 19, 2014, 07:03 PM |
| GORMAN KEVIN CHARLES | PRESIDENT AND CEO | Dec 19, 2014 | Sale | $24.01 | 15,000 | 360,150 | 180,952 | Dec 19, 2014, 07:03 PM |
| GORMAN KEVIN CHARLES | PRESIDENT AND CEO | Dec 18, 2014 | Sale | $23.24 | 55,000 | 1,278,200 | 180,952 | Dec 19, 2014, 07:03 PM |
| Coughlin Timothy P | Chief Financial Officer | Dec 19, 2014 | Option Exercise | $2.59 | 10,000 | 25,900 | 107,874 | Dec 19, 2014, 07:01 PM |
| Coughlin Timothy P | Chief Financial Officer | Dec 18, 2014 | Option Exercise | $2.59 | 20,000 | 51,800 | 117,874 | Dec 19, 2014, 07:01 PM |
| Coughlin Timothy P | Chief Financial Officer | Dec 18, 2014 | Sale | $23.18 | 20,000 | 463,600 | 107,874 | Dec 19, 2014, 07:01 PM |
| Coughlin Timothy P | Chief Financial Officer | Dec 19, 2014 | Sale | $24.02 | 10,000 | 240,200 | 97,874 | Dec 19, 2014, 07:01 PM |
| Bozigian Haig P. | Chief Development Officer | Dec 17, 2014 | Option Exercise | $2.59 | 15,002 | 38,855 | 93,581 | Dec 19, 2014, 02:36 PM |
| Bozigian Haig P. | Chief Development Officer | Dec 17, 2014 | Sale | $22.51 | 15,002 | 337,695 | 78,579 | Dec 19, 2014, 02:36 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Dec 17, 2014 | Option Exercise | $2.59 | 14,706 | 38,089 | 91,764 | Dec 19, 2014, 02:34 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Dec 17, 2014 | Sale | $22.50 | 14,706 | 330,885 | 77,058 | Dec 19, 2014, 02:34 PM |
| Gano Kyle | Chief Business Dev Officer | Dec 17, 2014 | Option Exercise | $5.00 | 4,957 | 24,785 | 28,695 | Dec 19, 2014, 02:32 PM |
| Gano Kyle | Chief Business Dev Officer | Dec 17, 2014 | Sale | $22.50 | 4,957 | 111,533 | 23,738 | Dec 19, 2014, 02:32 PM |
| MOLLICA JOSEPH A | Director | Dec 12, 2014 | Option Exercise | $21.97 | 4,333 | 95,196 | 19,175 | Dec 15, 2014, 07:28 PM |
| MOLLICA JOSEPH A | Director | Dec 12, 2014 | Option Exercise | $4.76 | 20,000 | 95,200 | 23,508 | Dec 15, 2014, 07:28 PM |
| Bozigian Haig P. | Chief Development Officer | Dec 15, 2014 | Option Exercise | $5.12 | 2,500 | 12,800 | 81,079 | Dec 15, 2014, 07:26 PM |
| Bozigian Haig P. | Chief Development Officer | Dec 12, 2014 | Option Exercise | $3.86 | 9,998 | 38,545 | 88,577 | Dec 15, 2014, 07:26 PM |
| Bozigian Haig P. | Chief Development Officer | Dec 15, 2014 | Sale | $21.72 | 2,500 | 54,300 | 78,579 | Dec 15, 2014, 07:26 PM |
| Bozigian Haig P. | Chief Development Officer | Dec 12, 2014 | Sale | $22.50 | 9,998 | 224,955 | 78,579 | Dec 15, 2014, 07:26 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Dec 15, 2014 | Option Exercise | $5.12 | 2,500 | 12,800 | 79,558 | Dec 15, 2014, 07:24 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Dec 12, 2014 | Option Exercise | $3.82 | 10,294 | 39,311 | 87,352 | Dec 15, 2014, 07:24 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Dec 15, 2014 | Sale | $21.71 | 2,500 | 54,275 | 77,058 | Dec 15, 2014, 07:24 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Dec 12, 2014 | Sale | $22.50 | 10,294 | 231,615 | 77,058 | Dec 15, 2014, 07:24 PM |
| Gano Kyle | Chief Business Dev Officer | Dec 12, 2014 | Option Exercise | $5.00 | 4,043 | 20,215 | 27,781 | Dec 15, 2014, 07:22 PM |
| Gano Kyle | Chief Business Dev Officer | Dec 12, 2014 | Sale | $22.50 | 4,043 | 90,968 | 23,738 | Dec 15, 2014, 07:22 PM |
| MITCHELL W THOMAS | Director | Dec 10, 2014 | Option Exercise | $4.76 | 7,000 | 33,320 | 8,000 | Dec 12, 2014, 05:52 PM |
| MITCHELL W THOMAS | Director | Dec 10, 2014 | Sale | $21.90 | 7,000 | 153,300 | 1,000 | Dec 12, 2014, 05:52 PM |
| OBrien Christopher Flint | Chief Medical Officer | Dec 11, 2014 | Option Exercise | $2.59 | 19,875 | 51,476 | 106,517 | Dec 12, 2014, 05:52 PM |
| OBrien Christopher Flint | Chief Medical Officer | Dec 10, 2014 | Option Exercise | $2.59 | 20,125 | 52,124 | 116,544 | Dec 12, 2014, 05:52 PM |
| OBrien Christopher Flint | Chief Medical Officer | Dec 11, 2014 | Sale | $22.10 | 19,875 | 439,238 | 96,544 | Dec 12, 2014, 05:52 PM |
| OBrien Christopher Flint | Chief Medical Officer | Dec 10, 2014 | Sale | $21.55 | 20,125 | 433,750 | 96,544 | Dec 12, 2014, 05:52 PM |
| Coughlin Timothy P | Chief Financial Officer | Dec 10, 2014 | Option Exercise | $3.85 | 20,000 | 77,100 | 107,874 | Dec 12, 2014, 05:48 PM |
| Coughlin Timothy P | Chief Financial Officer | Dec 10, 2014 | Sale | $21.48 | 20,000 | 429,500 | 97,874 | Dec 12, 2014, 05:48 PM |
| Coughlin Timothy P | Chief Financial Officer | Nov 28, 2014 | Sale | $20.14 | 10,000 | 201,400 | 97,874 | Dec 02, 2014, 04:05 PM |
| OBrien Christopher Flint | Chief Medical Officer | Nov 24, 2014 | Sale | $19.53 | 5,463 | 106,692 | 96,544 | Nov 25, 2014, 04:37 PM |
| OBrien Christopher Flint | Chief Medical Officer | Nov 17, 2014 | Sale | $19.51 | 11,300 | 220,463 | 96,544 | Nov 19, 2014, 05:18 PM |
| OBrien Christopher Flint | Chief Medical Officer | Nov 13, 2014 | Sale | $19.50 | 3,237 | 63,122 | 96,544 | Nov 17, 2014, 05:02 PM |
| OBrien Christopher Flint | Chief Medical Officer | Nov 10, 2014 | Sale | $18.62 | 20,000 | 372,400 | 96,544 | Nov 12, 2014, 04:18 PM |
| Coughlin Timothy P | Chief Financial Officer | Oct 31, 2014 | Sale | $19.00 | 10,000 | 190,000 | 97,874 | Nov 03, 2014, 06:19 PM |
| Coughlin Timothy P | Chief Financial Officer | Oct 30, 2014 | Sale | $18.62 | 10,000 | 186,200 | 97,874 | Oct 30, 2014, 05:51 PM |
| Coughlin Timothy P | Chief Financial Officer | Oct 28, 2014 | Sale | $18.00 | 10,000 | 180,000 | 97,874 | Oct 30, 2014, 05:51 PM |
| MITCHELL W THOMAS | Director | Oct 01, 2014 | Sale | $15.50 | 1,275 | 19,763 | 1,000 | Oct 03, 2014, 02:26 PM |
| LYONS GARY A | Director | Sep 15, 2014 | Sale | $15.66 | 20,000 | 313,200 | 284,164 | Sep 17, 2014, 02:32 PM |
| Nevinny Corinne H | Director | May 12, 2014 | Option Exercise | $14.47 | 10,258 | 148,433 | 3,273 | May 14, 2014, 02:17 PM |
| Nevinny Corinne H | Director | May 12, 2014 | Option Exercise | $12.37 | 12,000 | 148,440 | 13,531 | May 14, 2014, 02:17 PM |
| POPS RICHARD F | Director | May 12, 2014 | Option Exercise | $14.47 | 10,258 | 148,433 | 3,273 | May 14, 2014, 02:16 PM |
| POPS RICHARD F | Director | May 12, 2014 | Option Exercise | $12.37 | 12,000 | 148,440 | 13,531 | May 14, 2014, 02:16 PM |
| MOLLICA JOSEPH A | Director | Apr 16, 2014 | Option Exercise | $13.84 | 13,406 | 185,539 | 3,508 | Apr 18, 2014, 02:41 PM |
| MOLLICA JOSEPH A | Director | Apr 16, 2014 | Option Exercise | $12.37 | 15,000 | 185,550 | 16,914 | Apr 18, 2014, 02:41 PM |
| MITCHELL W THOMAS | Director | Apr 16, 2014 | Option Exercise | $13.84 | 10,725 | 148,434 | 2,275 | Apr 18, 2014, 02:38 PM |
| MITCHELL W THOMAS | Director | Apr 16, 2014 | Option Exercise | $12.37 | 12,000 | 148,440 | 13,000 | Apr 18, 2014, 02:38 PM |
| SHERWIN STEPHEN A | Director | Apr 16, 2014 | Option Exercise | $13.84 | 10,725 | 148,434 | 2,806 | Apr 18, 2014, 02:34 PM |
| SHERWIN STEPHEN A | Director | Apr 16, 2014 | Option Exercise | $12.37 | 12,000 | 148,440 | 13,531 | Apr 18, 2014, 02:34 PM |
| LYONS GARY A | Director | Mar 07, 2014 | Option Exercise | $17.50 | 53,331 | 933,293 | 304,164 | Mar 10, 2014, 07:16 PM |
| LYONS GARY A | Director | Mar 07, 2014 | Option Exercise | $10.98 | 85,000 | 933,300 | 357,495 | Mar 10, 2014, 07:16 PM |
| Bozigian Haig P. | CHIEF DEVELOPMENT OFFICER | Jan 17, 2014 | Option Exercise | $3.10 | 25,000 | 77,400 | 103,579 | Jan 21, 2014, 04:39 PM |
| Bozigian Haig P. | CHIEF DEVELOPMENT OFFICER | Jan 17, 2014 | Sale | $20.00 | 25,000 | 500,000 | 78,579 | Jan 21, 2014, 04:39 PM |
| Grigoriadis Dimitri E. | CHIEF RESEARCH OFFICER | Jan 17, 2014 | Option Exercise | $3.10 | 25,000 | 77,400 | 102,058 | Jan 21, 2014, 04:36 PM |
| Grigoriadis Dimitri E. | CHIEF RESEARCH OFFICER | Jan 17, 2014 | Sale | $20.00 | 25,000 | 500,000 | 77,058 | Jan 21, 2014, 04:36 PM |
| GORMAN KEVIN CHARLES | President and CEO | Jan 10, 2014 | Sale | $18.57 | 3,750 | 69,637 | 180,952 | Jan 13, 2014, 06:26 PM |
| Coughlin Timothy P | Chief Financial Officer | Jan 10, 2014 | Sale | $18.56 | 1,750 | 32,480 | 97,874 | Jan 13, 2014, 06:21 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 10, 2014 | Sale | $18.88 | 6,750 | 127,462 | 96,544 | Jan 13, 2014, 06:19 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 10, 2014 | Sale | $18.56 | 1,625 | 30,160 | 77,058 | Jan 13, 2014, 06:16 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 10, 2014 | Sale | $18.58 | 1,625 | 30,192 | 78,579 | Jan 13, 2014, 06:14 PM |
| Gano Kyle | Chief Business Dev Officer | Jan 10, 2014 | Sale | $18.57 | 1,250 | 23,212 | 23,738 | Jan 13, 2014, 06:13 PM |
| GORMAN KEVIN CHARLES | President and CEO | Jan 07, 2014 | Sale | $16.76 | 108,000 | 1,810,080 | 177,202 | Jan 08, 2014, 05:07 PM |
| Coughlin Timothy P | Chief Financial Officer | Jan 07, 2014 | Sale | $16.75 | 70,000 | 1,172,500 | 96,124 | Jan 08, 2014, 05:03 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jan 07, 2014 | Sale | $17.50 | 5,000 | 87,500 | 94,794 | Jan 08, 2014, 05:01 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jan 07, 2014 | Sale | $17.50 | 25,000 | 437,500 | 75,433 | Jan 08, 2014, 05:00 PM |
| Bozigian Haig P. | Chief Development Officer | Jan 07, 2014 | Sale | $17.50 | 25,000 | 437,500 | 76,954 | Jan 08, 2014, 05:00 PM |
| Gano Kyle | Chief Business Dev Officer | Sep 04, 2013 | Sale | $15.61 | 2,400 | 37,464 | 22,488 | Sep 05, 2013, 05:31 PM |
| OBrien Christopher Flint | Chief Medical Officer | Sep 03, 2013 | Sale | $16.00 | 5,000 | 80,000 | 94,794 | Sep 05, 2013, 05:30 PM |
| Coughlin Timothy P | Chief Financial Officer | Aug 21, 2013 | Sale | $15.05 | 19,035 | 286,477 | 96,124 | Aug 22, 2013, 04:22 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Aug 21, 2013 | Sale | $15.05 | 13,600 | 204,635 | 75,433 | Aug 22, 2013, 04:20 PM |
| Bozigian Haig P. | Chief Development Officer | Aug 21, 2013 | Sale | $15.04 | 13,999 | 210,552 | 76,954 | Aug 22, 2013, 04:19 PM |
| OBrien Christopher Flint | Chief Medical Officer | Aug 05, 2013 | Sale | $15.00 | 5,000 | 75,000 | 94,794 | Aug 07, 2013, 04:24 PM |
| Coughlin Timothy P | Chief Financial Officer | Aug 05, 2013 | Sale | $14.99 | 10,965 | 164,365 | 96,124 | Aug 07, 2013, 04:23 PM |
| MITCHELL W THOMAS | Director | Aug 06, 2013 | Sale | $14.70 | 1,531 | 22,506 | 1,000 | Aug 07, 2013, 04:22 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Aug 05, 2013 | Sale | $15.01 | 11,400 | 171,064 | 75,433 | Aug 07, 2013, 04:21 PM |
| Bozigian Haig P. | Chief Development Officer | Aug 05, 2013 | Sale | $15.00 | 11,001 | 165,015 | 76,954 | Aug 07, 2013, 04:20 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jul 12, 2013 | Sale | $14.50 | 5,000 | 72,500 | 94,794 | Jul 16, 2013, 05:49 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jun 28, 2013 | Sale | $13.50 | 7,500 | 101,250 | 94,794 | Jul 01, 2013, 05:39 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jun 27, 2013 | Sale | $13.00 | 3,857 | 50,141 | 94,794 | Jul 01, 2013, 05:39 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 27, 2013 | Sale | $13.00 | 3,837 | 49,881 | 75,433 | Jul 01, 2013, 05:34 PM |
| Bozigian Haig P. | Chief Development Officer | Jun 27, 2013 | Sale | $13.00 | 8,000 | 104,000 | 76,954 | Jul 01, 2013, 05:31 PM |
| Bozigian Haig P. | Chief Development Officer | Jun 24, 2013 | Sale | $12.72 | 769 | 9,782 | 76,954 | Jun 26, 2013, 05:40 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jun 21, 2013 | Sale | $12.59 | 14,926 | 187,861 | 94,794 | Jun 24, 2013, 07:32 PM |
| OBrien Christopher Flint | Chief Medical Officer | Jun 20, 2013 | Sale | $12.32 | 21,217 | 261,386 | 94,794 | Jun 24, 2013, 07:32 PM |
| Bozigian Haig P. | Chief Development Officer | Jun 21, 2013 | Sale | $12.66 | 23,962 | 303,375 | 76,954 | Jun 24, 2013, 07:27 PM |
| Bozigian Haig P. | Chief Development Officer | Jun 20, 2013 | Sale | $12.31 | 20,769 | 255,651 | 76,954 | Jun 24, 2013, 07:27 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 21, 2013 | Sale | $12.68 | 25,937 | 328,931 | 75,433 | Jun 24, 2013, 07:24 PM |
| Grigoriadis Dimitri E. | Chief Research Officer | Jun 20, 2013 | Sale | $12.30 | 20,900 | 257,086 | 75,433 | Jun 24, 2013, 07:24 PM |
| Nevinny Corinne H | Director | Mar 28, 2013 | Option Exercise | $12.15 | 10,469 | 127,198 | 1,531 | Apr 01, 2013, 05:28 PM |
| Nevinny Corinne H | Director | Mar 28, 2013 | Option Exercise | $10.60 | 12,000 | 127,200 | 12,000 | Apr 01, 2013, 05:28 PM |
| MITCHELL W THOMAS | Director | Mar 28, 2013 | Option Exercise | $12.15 | 10,469 | 127,198 | 2,531 | Apr 01, 2013, 05:26 PM |
| MITCHELL W THOMAS | Director | Mar 28, 2013 | Option Exercise | $10.60 | 12,000 | 127,200 | 13,000 | Apr 01, 2013, 05:26 PM |
| POPS RICHARD F | Director | Mar 28, 2013 | Option Exercise | $12.15 | 10,469 | 127,198 | 1,531 | Apr 01, 2013, 05:24 PM |
| POPS RICHARD F | Director | Mar 28, 2013 | Option Exercise | $10.60 | 12,000 | 127,200 | 12,000 | Apr 01, 2013, 05:24 PM |
| SHERWIN STEPHEN A | Director | Mar 28, 2013 | Option Exercise | $12.15 | 10,469 | 127,198 | 1,531 | Apr 01, 2013, 05:22 PM |
| SHERWIN STEPHEN A | Director | Mar 28, 2013 | Option Exercise | $10.60 | 12,000 | 127,200 | 12,000 | Apr 01, 2013, 05:22 PM |
| MOLLICA JOSEPH A | Director | Mar 28, 2013 | Option Exercise | $12.15 | 13,086 | 158,995 | 1,914 | Apr 01, 2013, 05:21 PM |
| MOLLICA JOSEPH A | Director | Mar 28, 2013 | Option Exercise | $10.60 | 15,000 | 159,000 | 15,000 | Apr 01, 2013, 05:21 PM |
| MITCHELL W THOMAS | Director | Dec 05, 2012 | Sale | $7.41 | 900 | 6,669 | 1,000 | Dec 07, 2012, 04:55 PM |
| BVF PARTNERS L P/IL | 10% Owner | Oct 12, 2011 | Buy | $5.95 | 29,500 | 175,672 | 3,527,700 | Oct 14, 2011, 04:15 PM |
| BVF PARTNERS L P/IL | 10% Owner | Oct 11, 2011 | Buy | $5.73 | 3,800 | 21,768 | 3,505,400 | Oct 12, 2011, 05:11 PM |
| BVF PARTNERS L P/IL | 10% Owner | Oct 10, 2011 | Buy | $5.59 | 44,700 | 249,779 | 3,501,600 | Oct 12, 2011, 05:11 PM |
| BVF PARTNERS L P/IL | 10% Owner | Oct 10, 2011 | Buy | $5.59 | 9,600 | 53,644 | 756,600 | Oct 12, 2011, 05:11 PM |
| BVF PARTNERS L P/IL | 10% Owner | Oct 10, 2011 | Buy | $5.59 | 15,800 | 88,289 | 1,230,465 | Oct 12, 2011, 05:11 PM |
| GORMAN KEVIN CHARLES | President and CEO | Feb 28, 2011 | Sale | $6.83 | 15,400 | 105,134 | 177,202 | Mar 02, 2011, 05:06 PM |
| Coughlin Timothy P | VP and Chief Financial Officer | Feb 28, 2011 | Sale | $6.83 | 12,320 | 84,104 | 96,124 | Mar 02, 2011, 05:04 PM |
| VALEUR JENSEN MARGARET E | EVP and General Counsel | Feb 28, 2011 | Sale | $6.83 | 12,320 | 84,104 | 118,256 | Mar 02, 2011, 05:02 PM |
| OBrien Christopher Flint | Sr. VP & Chief Medical Officer | Feb 28, 2011 | Sale | $6.83 | 12,320 | 84,091 | 94,794 | Mar 02, 2011, 05:00 PM |
| Grigoriadis Dimitri E. | Vice President, Research | Feb 28, 2011 | Sale | $6.82 | 12,320 | 84,075 | 75,433 | Mar 02, 2011, 04:59 PM |
| Bozigian Haig P. | Sr Vice President, Development | Feb 28, 2011 | Sale | $6.83 | 12,320 | 84,085 | 76,954 | Mar 02, 2011, 04:56 PM |
Load More Insider Transactions
Buy
Sale
Option Exercise
| Owner | Relationship | Date | Value($) |
| BENEVICH ERIC | Chief Commercial Officer | 04/15/2024 | 1,609,431 |
| BENEVICH ERIC | Chief Commercial Officer | 04/15/2024 | 2,643,020 |
| Delaet Ingrid | Chief Regulatory Officer | 03/21/2024 | 517,600 |
| Delaet Ingrid | Chief Regulatory Officer | 03/21/2024 | 725,320 |
| BENEVICH ERIC | Chief Commercial Officer | 03/14/2024 | 6,067,628 |
| BENEVICH ERIC | Chief Commercial Officer | 03/14/2024 | 10,453,418 |
| MORROW GEORGE J | Director | 03/14/2024 | 1,591,600 |
| MORROW GEORGE J | Director | 03/14/2024 | 5,576,710 |
| POPS RICHARD F | Director | 03/13/2024 | 992,032 |
| POPS RICHARD F | Director | 03/13/2024 | 3,255,621 |
| Delaet Ingrid | Chief Regulatory Officer | 03/13/2024 | 318,060 |
| Delaet Ingrid | Chief Regulatory Officer | 03/13/2024 | 420,419 |
| POPS RICHARD F | Director | 03/08/2024 | 72,692 |
| POPS RICHARD F | Director | 03/11/2024 | 4,276 |
| POPS RICHARD F | Director | 03/08/2024 | 238,078 |
| POPS RICHARD F | Director | 03/11/2024 | 14,000 |
| Delaet Ingrid | Chief Regulatory Officer | 03/11/2024 | 21,204 |
| Delaet Ingrid | Chief Regulatory Officer | 03/08/2024 | 190,836 |
| Delaet Ingrid | Chief Regulatory Officer | 03/11/2024 | 28,000 |
| Delaet Ingrid | Chief Regulatory Officer | 03/08/2024 | 252,053 |
| Delaet Ingrid | Chief Regulatory Officer | 02/29/2024 | 21,572 |
| Delaet Ingrid | Chief Regulatory Officer | 02/28/2024 | 517,107 |
| Delaet Ingrid | Chief Regulatory Officer | 02/28/2024 | 885,637 |
| Delaet Ingrid | Chief Regulatory Officer | 02/29/2024 | 36,994 |
| BENEVICH ERIC | Chief Commercial Officer | 02/28/2024 | 4,025,043 |
| BENEVICH ERIC | Chief Commercial Officer | 02/28/2024 | 10,101,607 |
| Norwalk Leslie V | Director | 02/27/2024 | 679,600 |
| Norwalk Leslie V | Director | 02/27/2024 | 1,085,388 |
| POPS RICHARD F | Director | 02/20/2024 | 194,700 |
| POPS RICHARD F | Director | 02/20/2024 | 1,987,047 |
| ROBERTS EIRY | Chief Medical Officer | 02/13/2024 | 148,122 |
| Onyia Jude | Chief Scientific Officer | 02/13/2024 | 190,371 |
| Lippoldt Darin | Chief Legal Officer | 02/13/2024 | 146,028 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/13/2024 | 376,700 |
| Gano Kyle | Chief Business Development Off | 02/13/2024 | 179,674 |
| Delaet Ingrid | Chief Regulatory Officer | 02/13/2024 | 95,253 |
| Cooke Julie | Chief Human Resources Officer | 02/13/2024 | 105,902 |
| Boyer David W. | Chief Corp. Affairs Officer | 02/13/2024 | 240,996 |
| BENEVICH ERIC | Chief Commercial Officer | 02/13/2024 | 146,050 |
| ABERNETHY MATT | Chief Financial Officer | 02/13/2024 | 179,612 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/13/2024 | 199,951 |
| Boyer David W. | Chief Corp. Affairs Officer | 02/08/2024 | 179,830 |
| Boyer David W. | Chief Corp. Affairs Officer | 02/06/2024 | 64,734 |
| Cooke Julie | Chief Human Resources Officer | 02/08/2024 | 179,995 |
| Cooke Julie | Chief Human Resources Officer | 02/06/2024 | 172,617 |
| ROBERTS EIRY | Chief Medical Officer | 02/08/2024 | 131,522 |
| ROBERTS EIRY | Chief Medical Officer | 02/06/2024 | 159,446 |
| Lippoldt Darin | Chief Legal Officer | 02/08/2024 | 122,289 |
| Lippoldt Darin | Chief Legal Officer | 02/06/2024 | 147,995 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/08/2024 | 305,052 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/06/2024 | 432,218 |
| Gano Kyle | Chief Business Development Off | 02/08/2024 | 131,519 |
| Gano Kyle | Chief Business Development Off | 02/06/2024 | 227,522 |
| BENEVICH ERIC | Chief Commercial Officer | 02/06/2024 | 181,910 |
| BENEVICH ERIC | Chief Commercial Officer | 02/08/2024 | 131,509 |
| ABERNETHY MATT | Chief Financial Officer | 02/08/2024 | 131,529 |
| ABERNETHY MATT | Chief Financial Officer | 02/06/2024 | 182,000 |
| ROBERTS EIRY | Chief Medical Officer | 01/31/2024 | 205,132 |
| Onyia Jude | Chief Scientific Officer | 01/31/2024 | 17,884 |
| Lippoldt Darin | Chief Legal Officer | 01/31/2024 | 175,810 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/31/2024 | 380,845 |
| Gano Kyle | Chief Business Development Off | 01/31/2024 | 216,813 |
| Delaet Ingrid | Chief Regulatory Officer | 02/01/2024 | 87,077 |
| Delaet Ingrid | Chief Regulatory Officer | 01/31/2024 | 59,899 |
| Cooke Julie | Chief Human Resources Officer | 01/31/2024 | 245,842 |
| Boyer David W. | Chief Corp. Affairs Officer | 01/31/2024 | 295,115 |
| BENEVICH ERIC | Chief Commercial Officer | 01/31/2024 | 169,927 |
| ABERNETHY MATT | Chief Financial Officer | 01/31/2024 | 180,539 |
| Lippoldt Darin | Chief Legal Officer | 01/22/2024 | 790,200 |
| Lippoldt Darin | Chief Legal Officer | 01/22/2024 | 1,398,553 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/08/2024 | 2,073,308 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/09/2024 | 1,215,031 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/09/2024 | 8,311,895 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/08/2024 | 14,016,523 |
| Gano Kyle | Chief Business Development Off | 01/02/2024 | 1,469,250 |
| Gano Kyle | Chief Business Development Off | 01/02/2024 | 9,860,195 |
| RASTETTER WILLIAM H | Director | 01/02/2024 | 259,600 |
| RASTETTER WILLIAM H | Director | 01/02/2024 | 1,451,927 |
| ROBERTS EIRY | Chief Medical Officer | 12/22/2023 | 1,267,448 |
| LYONS GARY A | Director | 12/22/2023 | 1,300,443 |
| Cooke Julie | Chief Human Resources Officer | 12/22/2023 | 1,752,900 |
| Cooke Julie | Chief Human Resources Officer | 12/22/2023 | 3,087,808 |
| ROBERTS EIRY | Chief Medical Officer | 12/12/2023 | 1,128,621 |
| ROBERTS EIRY | Chief Medical Officer | 12/12/2023 | 1,675,240 |
| ROBERTS EIRY | Chief Medical Officer | 12/07/2023 | 6,076,120 |
| ROBERTS EIRY | Chief Medical Officer | 12/08/2023 | 24,315 |
| ROBERTS EIRY | Chief Medical Officer | 12/07/2023 | 9,314,319 |
| ROBERTS EIRY | Chief Medical Officer | 12/08/2023 | 36,031 |
| ROBERTS EIRY | Chief Medical Officer | 12/06/2023 | 653,293 |
| ROBERTS EIRY | Chief Medical Officer | 12/06/2023 | 1,007,780 |
| Lippoldt Darin | Chief Legal Officer | 12/06/2023 | 900,689 |
| Lippoldt Darin | Chief Legal Officer | 12/06/2023 | 2,496,648 |
| LYONS GARY A | Director | 12/01/2023 | 64,900 |
| LYONS GARY A | Director | 12/01/2023 | 583,837 |
| Onyia Jude | Chief Scientific Officer | 11/29/2023 | 264,733 |
| Lippoldt Darin | Chief Legal Officer | 11/27/2023 | 1,225,911 |
| Boyer David W. | Chief Corp. Affairs Officer | 10/02/2023 | 161,921 |
| LYONS GARY A | Director | 09/12/2023 | 64,900 |
| LYONS GARY A | Director | 09/12/2023 | 575,120 |
| LYONS GARY A | Director | 09/01/2023 | 64,900 |
| LYONS GARY A | Director | 09/01/2023 | 550,316 |
| Cooke Julie | Chief Human Resources Officer | 09/01/2023 | 91,406 |
| Boyer David W. | Chief Corp. Affairs Officer | 08/30/2023 | 294,058 |
| Delaet Ingrid | Chief Regulatory Officer | 08/28/2023 | 153,861 |
| ROBERTS EIRY | Chief Medical Officer | 08/21/2023 | 343,388 |
| Onyia Jude | Chief Scientific Officer | 08/21/2023 | 343,368 |
| Lippoldt Darin | Chief Legal Officer | 08/21/2023 | 228,951 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 08/21/2023 | 1,001,816 |
| Gano Kyle | Chief Business Development Off | 08/21/2023 | 228,993 |
| Delaet Ingrid | Chief Regulatory Officer | 08/21/2023 | 150,820 |
| Cooke Julie | Chief Human Resources Officer | 08/21/2023 | 228,991 |
| Boyer David W. | Chief Corp. Affairs Officer | 08/21/2023 | 171,862 |
| BENEVICH ERIC | Chief Commercial Officer | 08/21/2023 | 171,836 |
| ABERNETHY MATT | Chief Financial Officer | 08/21/2023 | 228,958 |
| RASTETTER WILLIAM H | Director | 05/01/2023 | 96,914 |
| RASTETTER WILLIAM H | Director | 05/01/2023 | 436,135 |
| Cooke Julie | Chief Human Resources Officer | 05/01/2023 | 1,184,049 |
| Cooke Julie | Chief Human Resources Officer | 04/25/2023 | 10,382 |
| ROBERTS EIRY | Chief Medical Officer | 04/24/2023 | 1,490,059 |
| RASTETTER WILLIAM H | Director | 04/21/2023 | 136,823 |
| RASTETTER WILLIAM H | Director | 04/19/2023 | 20,463 |
| RASTETTER WILLIAM H | Director | 04/21/2023 | 633,787 |
| RASTETTER WILLIAM H | Director | 04/19/2023 | 94,819 |
| Cooke Julie | Chief Human Resources Officer | 02/06/2023 | 127,459 |
| Cooke Julie | Chief Human Resources Officer | 02/08/2023 | 137,883 |
| Cooke Julie | Chief Human Resources Officer | 02/07/2023 | 1,489,779 |
| ROBERTS EIRY | Chief Medical Officer | 02/08/2023 | 102,072 |
| ROBERTS EIRY | Chief Medical Officer | 02/07/2023 | 1,477,032 |
| ROBERTS EIRY | Chief Medical Officer | 02/06/2023 | 118,602 |
| Onyia Jude | Chief Scientific Officer | 02/07/2023 | 461,166 |
| Lloyd-Smith Malcolm | Chief Integration Officer | 02/07/2023 | 1,414,654 |
| Lloyd-Smith Malcolm | Chief Integration Officer | 02/06/2023 | 84,758 |
| Lloyd-Smith Malcolm | Chief Integration Officer | 02/08/2023 | 72,785 |
| Lippoldt Darin | Chief Legal Officer | 02/08/2023 | 94,815 |
| Lippoldt Darin | Chief Legal Officer | 02/07/2023 | 1,466,680 |
| Lippoldt Darin | Chief Legal Officer | 02/06/2023 | 110,141 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/06/2023 | 321,259 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/08/2023 | 237,185 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/07/2023 | 2,430,315 |
| Gano Kyle | Chief Business Development Off | 02/08/2023 | 101,910 |
| Gano Kyle | Chief Business Development Off | 02/07/2023 | 1,476,982 |
| Gano Kyle | Chief Business Development Off | 02/06/2023 | 169,028 |
| Boyer David W. | Chief Corp. Affairs Officer | 02/06/2023 | 25,346 |
| Boyer David W. | Chief Corp. Affairs Officer | 02/08/2023 | 72,876 |
| Boyer David W. | Chief Corp. Affairs Officer | 02/07/2023 | 2,488,519 |
| BENEVICH ERIC | Chief Commercial Officer | 02/08/2023 | 102,036 |
| BENEVICH ERIC | Chief Commercial Officer | 02/07/2023 | 1,780,868 |
| BENEVICH ERIC | Chief Commercial Officer | 02/06/2023 | 135,201 |
| ABERNETHY MATT | Chief Financial Officer | 02/06/2023 | 135,253 |
| ABERNETHY MATT | Chief Financial Officer | 02/08/2023 | 102,110 |
| ABERNETHY MATT | Chief Financial Officer | 02/07/2023 | 2,696,107 |
| ROBERTS EIRY | Chief Medical Officer | 01/31/2023 | 160,254 |
| Onyia Jude | Chief Scientific Officer | 01/31/2023 | 13,668 |
| Lloyd-Smith Malcolm | Chief Integration Officer | 01/31/2023 | 183,290 |
| Lippoldt Darin | Chief Legal Officer | 01/31/2023 | 137,464 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/31/2023 | 297,997 |
| Gano Kyle | Chief Business Development Off | 01/31/2023 | 169,486 |
| Cooke Julie | Chief Human Resources Officer | 01/31/2023 | 99,368 |
| Boyer David W. | Chief Corp. Affairs Officer | 01/31/2023 | 121,349 |
| BENEVICH ERIC | Chief Commercial Officer | 01/31/2023 | 132,710 |
| ABERNETHY MATT | Chief Financial Officer | 01/31/2023 | 141,108 |
| BENEVICH ERIC | Chief Commercial Officer | 01/06/2023 | 17,296 |
| BENEVICH ERIC | Chief Commercial Officer | 01/06/2023 | 50,000 |
| SHERWIN STEPHEN A | Director | 01/03/2023 | 385,350 |
| SHERWIN STEPHEN A | Director | 01/03/2023 | 3,565,728 |
| POPS RICHARD F | Director | 01/03/2023 | 190,650 |
| POPS RICHARD F | Director | 01/03/2023 | 1,788,045 |
| BENEVICH ERIC | Chief Commercial Officer | 11/30/2022 | 2,073,275 |
| BENEVICH ERIC | Chief Commercial Officer | 11/30/2022 | 6,295,100 |
| Onyia Jude | Chief Scientific Officer | 11/29/2022 | 284,161 |
| BENEVICH ERIC | Chief Commercial Officer | 11/10/2022 | 4,178 |
| BENEVICH ERIC | Chief Commercial Officer | 11/08/2022 | 1,027,496 |
| BENEVICH ERIC | Chief Commercial Officer | 11/10/2022 | 12,536 |
| BENEVICH ERIC | Chief Commercial Officer | 11/08/2022 | 3,082,314 |
| Lippoldt Darin | Chief Legal Officer | 11/08/2022 | 219,746 |
| Lippoldt Darin | Chief Legal Officer | 11/08/2022 | 635,443 |
| Cooke Julie | Chief Human Resources Officer | 11/08/2022 | 453,232 |
| Cooke Julie | Chief Human Resources Officer | 11/08/2022 | 698,950 |
| Lippoldt Darin | Chief Legal Officer | 11/03/2022 | 195,358 |
| Lippoldt Darin | Chief Legal Officer | 11/03/2022 | 564,849 |
| Cooke Julie | Chief Human Resources Officer | 11/02/2022 | 92,721 |
| Cooke Julie | Chief Human Resources Officer | 11/03/2022 | 588,747 |
| Cooke Julie | Chief Human Resources Officer | 11/03/2022 | 908,036 |
| Cooke Julie | Chief Human Resources Officer | 11/02/2022 | 142,962 |
| BENEVICH ERIC | Chief Commercial Officer | 11/03/2022 | 374,683 |
| BENEVICH ERIC | Chief Commercial Officer | 11/02/2022 | 16,712 |
| BENEVICH ERIC | Chief Commercial Officer | 11/03/2022 | 1,121,179 |
| BENEVICH ERIC | Chief Commercial Officer | 11/02/2022 | 50,000 |
| LYONS GARY A | Director | 10/31/2022 | 190,650 |
| LYONS GARY A | Director | 10/31/2022 | 1,721,400 |
| Lippoldt Darin | Chief Legal Officer | 11/02/2022 | 17,296 |
| Lippoldt Darin | Chief Legal Officer | 11/01/2022 | 432,400 |
| Lippoldt Darin | Chief Legal Officer | 11/02/2022 | 50,000 |
| Lippoldt Darin | Chief Legal Officer | 11/01/2022 | 1,200,900 |
| Boyer David W. | Chief Corp. Affairs Officer | 10/31/2022 | 147,785 |
| Lippoldt Darin | Chief Legal Officer | 10/27/2022 | 212,871 |
| Lippoldt Darin | Chief Legal Officer | 10/26/2022 | 219,529 |
| Lippoldt Darin | Chief Legal Officer | 10/26/2022 | 583,967 |
| Lippoldt Darin | Chief Legal Officer | 10/27/2022 | 566,332 |
| BENEVICH ERIC | Chief Commercial Officer | 10/17/2022 | 549,682 |
| Boyer David W. | Chief Corp. Affairs Officer | 10/03/2022 | 153,170 |
| LYONS GARY A | Director | 10/04/2022 | 552,710 |
| Lippoldt Darin | Chief Legal Officer | 10/04/2022 | 432,400 |
| Lippoldt Darin | Chief Legal Officer | 10/04/2022 | 1,110,450 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 08/15/2022 | 369,663 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 08/12/2022 | 774,973 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 08/12/2022 | 2,281,335 |
| Cooke Julie | Chief Human Resources Officer | 08/05/2022 | 181,600 |
| Cooke Julie | Chief Human Resources Officer | 06/27/2022 | 75,400 |
| POPS RICHARD F | Director | 05/09/2022 | 99,900 |
| POPS RICHARD F | Director | 05/09/2022 | 1,144,463 |
| LYONS GARY A | Director | 04/25/2022 | 99,900 |
| LYONS GARY A | Director | 04/25/2022 | 1,391,392 |
| RASTETTER WILLIAM H | Director | 04/01/2022 | 133,200 |
| RASTETTER WILLIAM H | Director | 04/01/2022 | 1,018,366 |
| Lippoldt Darin | Chief Legal Officer | 03/22/2022 | 803,656 |
| Lippoldt Darin | Chief Legal Officer | 03/18/2022 | 28,500 |
| Boyer David W. | Chief Corp. Affairs Officer | 02/08/2022 | 55,736 |
| Boyer David W. | Chief Corp. Affairs Officer | 02/07/2022 | 19,457 |
| ROBERTS EIRY | Chief Medical Officer | 02/07/2022 | 221,660 |
| ROBERTS EIRY | Chief Medical Officer | 02/08/2022 | 77,931 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/08/2022 | 55,751 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/07/2022 | 216,417 |
| Lippoldt Darin | Chief Legal Officer | 02/08/2022 | 72,435 |
| Lippoldt Darin | Chief Legal Officer | 02/07/2022 | 255,725 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/07/2022 | 703,907 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/08/2022 | 180,768 |
| Gano Kyle | Chief Business Development Off | 02/08/2022 | 78,079 |
| Gano Kyle | Chief Business Development Off | 02/07/2022 | 476,549 |
| Cooke Julie | Chief Human Resources Officer | 02/08/2022 | 55,689 |
| Cooke Julie | Chief Human Resources Officer | 02/07/2022 | 174,038 |
| BENEVICH ERIC | Chief Commercial Officer | 02/08/2022 | 78,073 |
| BENEVICH ERIC | Chief Commercial Officer | 02/07/2022 | 332,748 |
| ABERNETHY MATT | Chief Financial Officer | 02/08/2022 | 78,058 |
| ABERNETHY MATT | Chief Financial Officer | 02/07/2022 | 267,428 |
| SHERWIN STEPHEN A | Director | 01/24/2022 | 99,900 |
| SHERWIN STEPHEN A | Director | 01/24/2022 | 1,116,378 |
| ROBERTS EIRY | Chief Medical Officer | 01/10/2022 | 196,088 |
| Gano Kyle | Chief Business Development Off | 01/05/2022 | 244,784 |
| Gano Kyle | Chief Business Development Off | 01/05/2022 | 2,416,751 |
| ABERNETHY MATT | Chief Financial Officer | 12/01/2021 | 135,852 |
| LYONS GARY A | Director | 10/07/2021 | 525,295 |
| Grigoriadis Dimitri E. | Chief Research Officer | 10/07/2021 | 216,200 |
| Grigoriadis Dimitri E. | Chief Research Officer | 10/07/2021 | 838,510 |
| Cooke Julie | Chief Human Resources Officer | 10/04/2021 | 100,408 |
| BENEVICH ERIC | Chief Commercial Officer | 08/16/2021 | 504,395 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 07/27/2021 | 1,567,336 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/10/2021 | 61,183 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/10/2021 | 203,925 |
| Gano Kyle | Chief Business Development Off | 02/08/2021 | 431,518 |
| Gano Kyle | Chief Business Development Off | 02/05/2021 | 305,185 |
| ABERNETHY MATT | Chief Financial Officer | 02/08/2021 | 339,942 |
| Bozigian Haig P. | Chief Development Officer | 02/08/2021 | 448,748 |
| Bozigian Haig P. | Chief Development Officer | 02/05/2021 | 80,108 |
| BENEVICH ERIC | Chief Commercial Officer | 02/08/2021 | 498,843 |
| BENEVICH ERIC | Chief Commercial Officer | 02/05/2021 | 92,247 |
| Cooke Julie | Chief Human Resources Officer | 02/08/2021 | 156,189 |
| Cooke Julie | Chief Human Resources Officer | 02/05/2021 | 68,887 |
| ROBERTS EIRY | Chief Medical Officer | 02/08/2021 | 275,944 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/08/2021 | 380,928 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/05/2021 | 98,739 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/08/2021 | 315,999 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/05/2021 | 68,822 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/08/2021 | 1,221,862 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/05/2021 | 276,505 |
| Lippoldt Darin | Chief Legal Officer | 02/09/2021 | 1,302,622 |
| Lippoldt Darin | Chief Legal Officer | 02/08/2021 | 397,675 |
| Lippoldt Darin | Chief Legal Officer | 02/05/2021 | 69,003 |
| Lippoldt Darin | Chief Legal Officer | 02/09/2021 | 4,204,824 |
| LYONS GARY A | Director | 01/26/2021 | 48,000 |
| LYONS GARY A | Director | 01/25/2021 | 192,046 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 01/25/2021 | 605,470 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 01/26/2021 | 39,589 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 01/26/2021 | 131,966 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 01/25/2021 | 2,107,814 |
| BENEVICH ERIC | Chief Commercial Officer | 01/26/2021 | 12,534 |
| BENEVICH ERIC | Chief Commercial Officer | 01/25/2021 | 145,269 |
| BENEVICH ERIC | Chief Commercial Officer | 01/26/2021 | 48,000 |
| BENEVICH ERIC | Chief Commercial Officer | 01/25/2021 | 609,370 |
| ROBERTS EIRY | Chief Medical Officer | 01/08/2021 | 292,297 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/08/2021 | 2,667,797 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/08/2021 | 33,973,945 |
| ABERNETHY MATT | Chief Financial Officer | 12/01/2020 | 155,721 |
| BENEVICH ERIC | Chief Commercial Officer | 11/12/2020 | 204,723 |
| ROBERTS EIRY | Chief Medical Officer | 11/12/2020 | 204,810 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 11/12/2020 | 204,776 |
| Lippoldt Darin | Chief Legal Officer | 11/12/2020 | 204,755 |
| Grigoriadis Dimitri E. | Chief Research Officer | 11/12/2020 | 204,784 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 11/12/2020 | 307,748 |
| Gano Kyle | Chief Business Development Off | 11/12/2020 | 204,770 |
| Cooke Julie | Chief Human Resources Officer | 11/12/2020 | 204,778 |
| Bozigian Haig P. | Chief Development Officer | 11/12/2020 | 204,806 |
| ABERNETHY MATT | Chief Financial Officer | 11/12/2020 | 204,810 |
| BENEVICH ERIC | Chief Commercial Officer | 11/02/2020 | 741,214 |
| BENEVICH ERIC | Chief Commercial Officer | 11/02/2020 | 1,987,972 |
| Cooke Julie | Chief Human Resources Officer | 10/02/2020 | 94,022 |
| ROBERTS EIRY | Chief Medical Officer | 08/05/2020 | 268,224 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 08/05/2020 | 268,278 |
| Lippoldt Darin | Chief Legal Officer | 08/05/2020 | 268,296 |
| Grigoriadis Dimitri E. | Chief Research Officer | 08/05/2020 | 268,199 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 08/05/2020 | 403,101 |
| Gano Kyle | Chief Business Development Off | 08/05/2020 | 268,285 |
| Cooke Julie | Chief Human Resources Officer | 08/05/2020 | 268,382 |
| Bozigian Haig P. | Chief Development Officer | 08/05/2020 | 268,323 |
| BENEVICH ERIC | Chief Commercial Officer | 08/05/2020 | 268,253 |
| ABERNETHY MATT | Chief Financial Officer | 08/05/2020 | 268,355 |
| Lippoldt Darin | Chief Legal Officer | 07/09/2020 | 59,635 |
| Lippoldt Darin | Chief Legal Officer | 07/09/2020 | 225,385 |
| ROBERTS EIRY | Chief Medical Officer | 06/23/2020 | 389,050 |
| ROBERTS EIRY | Chief Medical Officer | 06/23/2020 | 650,000 |
| Lippoldt Darin | Chief Legal Officer | 06/23/2020 | 164,950 |
| Lippoldt Darin | Chief Legal Officer | 06/23/2020 | 650,000 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/11/2020 | 199,976 |
| Lippoldt Darin | Chief Legal Officer | 05/18/2020 | 164,950 |
| Lippoldt Darin | Chief Legal Officer | 05/18/2020 | 600,000 |
| Grigoriadis Dimitri E. | Chief Research Officer | 05/19/2020 | 359,900 |
| Grigoriadis Dimitri E. | Chief Research Officer | 05/18/2020 | 359,900 |
| Grigoriadis Dimitri E. | Chief Research Officer | 05/19/2020 | 5,409,950 |
| Grigoriadis Dimitri E. | Chief Research Officer | 05/18/2020 | 1,199,800 |
| Bozigian Haig P. | Chief Development Officer | 05/12/2020 | 3,884,054 |
| Bozigian Haig P. | Chief Development Officer | 05/12/2020 | 7,075,378 |
| ABERNETHY MATT | Chief Financial Officer | 05/07/2020 | 1,104,000 |
| ABERNETHY MATT | Chief Financial Officer | 05/07/2020 | 1,653,135 |
| Grigoriadis Dimitri E. | Chief Research Officer | 05/07/2020 | 915,456 |
| SHERWIN STEPHEN A | Director | 04/28/2020 | 1,757,966 |
| ABERNETHY MATT | Chief Financial Officer | 04/28/2020 | 178,435 |
| ROBERTS EIRY | Chief Medical Officer | 04/24/2020 | 192,376 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 04/24/2020 | 192,329 |
| Lippoldt Darin | Chief Legal Officer | 04/24/2020 | 192,416 |
| Grigoriadis Dimitri E. | Chief Research Officer | 04/24/2020 | 192,258 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 04/24/2020 | 289,016 |
| Gano Kyle | Chief Business Development Off | 04/24/2020 | 192,377 |
| Cooke Julie | Chief Human Resources Officer | 04/24/2020 | 192,364 |
| Bozigian Haig P. | Chief Development Officer | 04/24/2020 | 192,351 |
| BENEVICH ERIC | Chief Commercial Officer | 04/24/2020 | 192,338 |
| ABERNETHY MATT | Chief Financial Officer | 04/24/2020 | 192,467 |
| BENEVICH ERIC | Chief Commercial Officer | 04/15/2020 | 817,018 |
| ROBERTS EIRY | Chief Medical Officer | 02/07/2020 | 167,675 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/10/2020 | 1,728,147 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/10/2020 | 3,029,086 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/07/2020 | 104,826 |
| Lippoldt Darin | Chief Legal Officer | 02/07/2020 | 157,247 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/07/2020 | 125,833 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/07/2020 | 335,697 |
| Gano Kyle | Chief Business Development Off | 02/07/2020 | 167,711 |
| Cooke Julie | Chief Human Resources Officer | 02/07/2020 | 94,276 |
| Bozigian Haig P. | Chief Development Officer | 02/07/2020 | 167,701 |
| BENEVICH ERIC | Chief Commercial Officer | 02/07/2020 | 209,748 |
| ABERNETHY MATT | Chief Financial Officer | 02/07/2020 | 209,807 |
| Gano Kyle | Chief Business Development Off | 02/06/2020 | 101,413 |
| Gano Kyle | Chief Business Development Off | 02/05/2020 | 380,262 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/06/2020 | 81,456 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/05/2020 | 166,894 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/06/2020 | 151,257 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/05/2020 | 200,734 |
| Lippoldt Darin | Chief Legal Officer | 02/06/2020 | 121,555 |
| Lippoldt Darin | Chief Legal Officer | 02/05/2020 | 180,206 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/05/2020 | 561,726 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/06/2020 | 441,066 |
| Cooke Julie | Chief Human Resources Officer | 02/05/2020 | 62,417 |
| Bozigian Haig P. | Chief Development Officer | 02/06/2020 | 141,671 |
| Bozigian Haig P. | Chief Development Officer | 02/05/2020 | 210,779 |
| BENEVICH ERIC | Chief Commercial Officer | 02/06/2020 | 141,560 |
| BENEVICH ERIC | Chief Commercial Officer | 02/05/2020 | 201,311 |
| ROBERTS EIRY | Chief Medical Officer | 01/08/2020 | 292,444 |
| ABERNETHY MATT | Chief Financial Officer | 12/02/2019 | 191,360 |
| Grigoriadis Dimitri E. | Chief Research Officer | 11/18/2019 | 179,950 |
| Grigoriadis Dimitri E. | Chief Research Officer | 11/18/2019 | 579,900 |
| LYONS GARY A | Director | 11/08/2019 | 550,000 |
| Lippoldt Darin | Chief Legal Officer | 11/08/2019 | 329,900 |
| Lippoldt Darin | Chief Legal Officer | 11/08/2019 | 1,100,057 |
| LYONS GARY A | Director | 11/01/2019 | 501,105 |
| Grigoriadis Dimitri E. | Chief Research Officer | 11/01/2019 | 336,102 |
| Grigoriadis Dimitri E. | Chief Research Officer | 11/01/2019 | 1,022,295 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 10/14/2019 | 153,820 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 10/14/2019 | 904,487 |
| Cooke Julie | Chief Human Resources Officer | 10/02/2019 | 87,409 |
| Lippoldt Darin | Chief Legal Officer | 09/03/2019 | 222,221 |
| Lippoldt Darin | Chief Legal Officer | 09/03/2019 | 673,600 |
| Lippoldt Darin | Chief Legal Officer | 08/27/2019 | 52,784 |
| Lippoldt Darin | Chief Legal Officer | 08/23/2019 | 54,895 |
| Lippoldt Darin | Chief Legal Officer | 08/27/2019 | 160,000 |
| Lippoldt Darin | Chief Legal Officer | 08/23/2019 | 166,555 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 08/09/2019 | 99,993 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 08/08/2019 | 228,018 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 08/07/2019 | 23,893 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 08/06/2019 | 440,889 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 08/08/2019 | 2,518,154 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 08/07/2019 | 262,440 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 08/06/2019 | 4,844,380 |
| LYONS GARY A | Director | 07/30/2019 | 920,686 |
| Lippoldt Darin | Chief Legal Officer | 07/30/2019 | 287,333 |
| Lippoldt Darin | Chief Legal Officer | 07/30/2019 | 1,458,569 |
| Grigoriadis Dimitri E. | Chief Research Officer | 07/30/2019 | 1,649,500 |
| Grigoriadis Dimitri E. | Chief Research Officer | 07/30/2019 | 5,575,438 |
| Bozigian Haig P. | Chief Development Officer | 07/30/2019 | 1,725,705 |
| Bozigian Haig P. | Chief Development Officer | 07/30/2019 | 4,114,858 |
| Bozigian Haig P. | Chief Development Officer | 07/15/2019 | 1,012,133 |
| Bozigian Haig P. | Chief Development Officer | 07/15/2019 | 2,684,506 |
| BENEVICH ERIC | Chief Commercial Officer | 07/15/2019 | 510,201 |
| Bozigian Haig P. | Chief Development Officer | 07/10/2019 | 234,889 |
| Bozigian Haig P. | Chief Development Officer | 07/11/2019 | 3,299 |
| Bozigian Haig P. | Chief Development Officer | 07/11/2019 | 8,759 |
| Bozigian Haig P. | Chief Development Officer | 07/10/2019 | 623,958 |
| Bozigian Haig P. | Chief Development Officer | 06/18/2019 | 69,279 |
| Bozigian Haig P. | Chief Development Officer | 06/18/2019 | 184,417 |
| Bozigian Haig P. | Chief Development Officer | 06/13/2019 | 357,469 |
| Bozigian Haig P. | Chief Development Officer | 06/13/2019 | 1,426,628 |
| Bozigian Haig P. | Chief Development Officer | 06/03/2019 | 67,292 |
| Bozigian Haig P. | Chief Development Officer | 06/03/2019 | 293,719 |
| Bozigian Haig P. | Chief Development Officer | 05/31/2019 | 378,028 |
| Bozigian Haig P. | Chief Development Officer | 05/31/2019 | 1,640,581 |
| Bozigian Haig P. | Chief Development Officer | 05/24/2019 | 342,551 |
| Bozigian Haig P. | Chief Development Officer | 05/24/2019 | 1,399,434 |
| Bozigian Haig P. | Chief Development Officer | 05/22/2019 | 25,467 |
| Bozigian Haig P. | Chief Development Officer | 05/22/2019 | 104,037 |
| Bozigian Haig P. | Chief Development Officer | 05/16/2019 | 1,171,789 |
| Bozigian Haig P. | Chief Development Officer | 05/16/2019 | 5,341,893 |
| Grigoriadis Dimitri E. | Chief Research Officer | 05/13/2019 | 125,007 |
| Bozigian Haig P. | Chief Development Officer | 05/13/2019 | 299,177 |
| Bozigian Haig P. | Chief Development Officer | 05/13/2019 | 2,608,813 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/06/2019 | 76,894 |
| Lippoldt Darin | Chief Legal Officer | 02/06/2019 | 66,063 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/06/2019 | 44,622 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/06/2019 | 344,986 |
| Gano Kyle | Chief Business Development Off | 02/06/2019 | 63,673 |
| Bozigian Haig P. | Chief Development Officer | 02/06/2019 | 76,859 |
| BENEVICH ERIC | Chief Commercial Officer | 02/06/2019 | 76,883 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/05/2019 | 112,119 |
| Lippoldt Darin | Chief Legal Officer | 02/05/2019 | 107,911 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/05/2019 | 94,338 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/04/2019 | 121,167 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/05/2019 | 395,895 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/04/2019 | 275,321 |
| Gano Kyle | Chief Business Development Off | 02/05/2019 | 214,482 |
| Gano Kyle | Chief Business Development Off | 02/04/2019 | 121,186 |
| Bozigian Haig P. | Chief Development Officer | 02/05/2019 | 118,986 |
| Bozigian Haig P. | Chief Development Officer | 02/04/2019 | 121,139 |
| BENEVICH ERIC | Chief Commercial Officer | 02/05/2019 | 119,427 |
| ROBERTS EIRY | Chief Medical Officer | 01/08/2019 | 156,159 |
| ABERNETHY MATT | Chief Financial Officer | 12/03/2018 | 106,020 |
| POPS RICHARD F | Director | 11/26/2018 | 376,790 |
| POPS RICHARD F | Director | 11/12/2018 | 425,894 |
| Bozigian Haig P. | Chief Development Officer | 11/08/2018 | 314,147 |
| Bozigian Haig P. | Chief Development Officer | 11/08/2018 | 3,992,450 |
| Bozigian Haig P. | Chief Development Officer | 11/07/2018 | 371,105 |
| Bozigian Haig P. | Chief Development Officer | 11/06/2018 | 339,026 |
| Bozigian Haig P. | Chief Development Officer | 11/07/2018 | 3,238,139 |
| Bozigian Haig P. | Chief Development Officer | 11/06/2018 | 1,037,170 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 11/07/2018 | 50,985 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 11/06/2018 | 88,065 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 11/07/2018 | 363,000 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 11/06/2018 | 627,097 |
| LYONS GARY A | Director | 11/02/2018 | 1,716,210 |
| POPS RICHARD F | Director | 10/29/2018 | 589,237 |
| Grigoriadis Dimitri E. | Chief Research Officer | 09/04/2018 | 399,977 |
| Gano Kyle | Chief Business Development Off | 08/01/2018 | 244,784 |
| Gano Kyle | Chief Business Development Off | 08/01/2018 | 3,250,590 |
| Grigoriadis Dimitri E. | Chief Research Officer | 08/01/2018 | 451,001 |
| Grigoriadis Dimitri E. | Chief Research Officer | 08/01/2018 | 2,532,420 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 06/28/2018 | 533,416 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/20/2018 | 450,570 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/20/2018 | 2,415,000 |
| LYONS GARY A | Director | 06/13/2018 | 1,488,549 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/14/2018 | 54,558 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/13/2018 | 949,292 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/14/2018 | 278,500 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/13/2018 | 8,372,246 |
| SHERWIN STEPHEN A | Director | 06/11/2018 | 984,420 |
| BENEVICH ERIC | Chief Commercial Officer | 06/01/2018 | 1,202,164 |
| Nevinny Corinne H | Director | 05/07/2018 | 415,625 |
| Nevinny Corinne H | Director | 05/02/2018 | 105,706 |
| Nevinny Corinne H | Director | 05/02/2018 | 105,750 |
| POPS RICHARD F | Director | 05/01/2018 | 105,741 |
| POPS RICHARD F | Director | 05/01/2018 | 105,750 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 05/01/2018 | 730,552 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 05/01/2018 | 10,241,734 |
| SHERWIN STEPHEN A | Director | 04/26/2018 | 105,735 |
| SHERWIN STEPHEN A | Director | 04/26/2018 | 105,750 |
| LYONS GARY A | Director | 04/03/2018 | 105,728 |
| LYONS GARY A | Director | 04/03/2018 | 105,750 |
| Lippoldt Darin | Chief Legal Officer | 03/05/2018 | 35,919 |
| Lippoldt Darin | Chief Legal Officer | 03/05/2018 | 175,090 |
| Gano Kyle | Chief Business Development Off | 03/05/2018 | 204,572 |
| Gano Kyle | Chief Business Development Off | 03/05/2018 | 2,128,500 |
| Bozigian Haig P. | Chief Development Officer | 03/05/2018 | 976,703 |
| Bozigian Haig P. | Chief Development Officer | 03/05/2018 | 6,828,570 |
| LYONS GARY A | Director | 02/15/2018 | 423,341 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/12/2018 | 126,375 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/09/2018 | 621,571 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/12/2018 | 1,167,453 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/09/2018 | 5,596,720 |
| OBrien Christopher Flint | Former Chief Medical Officer | 02/06/2018 | 83,635 |
| OBrien Christopher Flint | Former Chief Medical Officer | 02/05/2018 | 217,341 |
| LYONS GARY A | Director | 02/05/2018 | 415,380 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/06/2018 | 108,379 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/05/2018 | 79,863 |
| Lippoldt Darin | Chief Legal Officer | 02/06/2018 | 64,912 |
| Lippoldt Darin | Chief Legal Officer | 02/05/2018 | 35,919 |
| Lippoldt Darin | Chief Legal Officer | 02/05/2018 | 227,494 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/06/2018 | 43,549 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/05/2018 | 169,997 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/06/2018 | 337,426 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/06/2018 | 576,000 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/05/2018 | 498,164 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/06/2018 | 8,006,620 |
| Bozigian Haig P. | Chief Development Officer | 02/06/2018 | 75,634 |
| Bozigian Haig P. | Chief Development Officer | 02/05/2018 | 187,977 |
| BENEVICH ERIC | Chief Commercial Officer | 02/06/2018 | 75,634 |
| BENEVICH ERIC | Chief Commercial Officer | 02/05/2018 | 68,174 |
| Gano Kyle | Chief Business Development Off | 02/06/2018 | 54,272 |
| Gano Kyle | Chief Business Development Off | 02/05/2018 | 169,914 |
| RASTETTER WILLIAM H | Director | 01/24/2018 | 141,000 |
| RASTETTER WILLIAM H | Director | 01/24/2018 | 855,000 |
| OBrien Christopher Flint | Chief Medical Officer | 01/16/2018 | 138,499 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/16/2018 | 128,563 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/16/2018 | 295,820 |
| Gano Kyle | Chief Business Development Off | 01/16/2018 | 128,460 |
| Bozigian Haig P. | Chief Development Officer | 01/16/2018 | 128,575 |
| Lippoldt Darin | Chief Legal Officer | 01/03/2018 | 35,919 |
| Lippoldt Darin | Chief Legal Officer | 01/03/2018 | 157,053 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 01/02/2018 | 279,398 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 01/02/2018 | 1,401,823 |
| Lippoldt Darin | Chief Legal Officer | 12/28/2017 | 276,552 |
| Lippoldt Darin | Chief Legal Officer | 12/28/2017 | 1,142,775 |
| Lippoldt Darin | Chief Legal Officer | 12/08/2017 | 53,633 |
| Lippoldt Darin | Chief Legal Officer | 12/08/2017 | 221,625 |
| Lippoldt Darin | Chief Legal Officer | 12/04/2017 | 113,964 |
| Lippoldt Darin | Chief Legal Officer | 12/04/2017 | 471,160 |
| LYONS GARY A | Director | 12/01/2017 | 729,182 |
| Lippoldt Darin | Chief Legal Officer | 11/15/2017 | 179,685 |
| Lippoldt Darin | Chief Legal Officer | 11/15/2017 | 723,191 |
| Grigoriadis Dimitri E. | Chief Research Officer | 11/08/2017 | 2,237,343 |
| OBrien Christopher Flint | Chief Medical Officer | 11/02/2017 | 457,320 |
| OBrien Christopher Flint | Chief Medical Officer | 11/02/2017 | 3,681,641 |
| Gano Kyle | Chief Business Development Off | 11/02/2017 | 214,810 |
| Gano Kyle | Chief Business Development Off | 11/02/2017 | 1,763,319 |
| OBrien Christopher Flint | Chief Medical Officer | 10/02/2017 | 59,901 |
| OBrien Christopher Flint | Chief Medical Officer | 10/02/2017 | 422,702 |
| Gano Kyle | Chief Business Development Off | 09/06/2017 | 176,399 |
| Gano Kyle | Chief Business Development Off | 09/06/2017 | 1,223,580 |
| Lippoldt Darin | Chief Legal Officer | 09/06/2017 | 1,815 |
| Lippoldt Darin | Chief Legal Officer | 09/06/2017 | 6,000 |
| Gano Kyle | Chief Business Development Off | 09/06/2017 | 39,851 |
| Gano Kyle | Chief Business Development Off | 09/06/2017 | 276,420 |
| Bozigian Haig P. | Chief Development Officer | 09/06/2017 | 350,137 |
| Bozigian Haig P. | Chief Development Officer | 09/06/2017 | 1,575,000 |
| OBrien Christopher Flint | Chief Medical Officer | 09/05/2017 | 457,395 |
| OBrien Christopher Flint | Chief Medical Officer | 09/05/2017 | 3,036,978 |
| Lippoldt Darin | Chief Legal Officer | 08/09/2017 | 90,750 |
| Lippoldt Darin | Chief Legal Officer | 08/09/2017 | 275,000 |
| Grigoriadis Dimitri E. | Chief Research Officer | 08/09/2017 | 88,439 |
| Grigoriadis Dimitri E. | Chief Research Officer | 08/09/2017 | 844,470 |
| Bozigian Haig P. | Chief Development Officer | 08/04/2017 | 317,200 |
| Bozigian Haig P. | Chief Development Officer | 08/04/2017 | 1,125,000 |
| OBrien Christopher Flint | Chief Medical Officer | 07/27/2017 | 75,549 |
| OBrien Christopher Flint | Chief Medical Officer | 07/27/2017 | 436,700 |
| Grigoriadis Dimitri E. | Chief Research Officer | 05/23/2017 | 533,900 |
| OBrien Christopher Flint | Chief Medical Officer | 05/18/2017 | 671,915 |
| OBrien Christopher Flint | Chief Medical Officer | 05/18/2017 | 5,632,405 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 05/19/2017 | 76,941 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 05/18/2017 | 76,941 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 05/18/2017 | 265,235 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 05/19/2017 | 268,920 |
| Lippoldt Darin | Chief Legal Officer | 05/18/2017 | 181,500 |
| Lippoldt Darin | Chief Legal Officer | 05/18/2017 | 532,700 |
| Nevinny Corinne H | Director | 05/05/2017 | 269,900 |
| POPS RICHARD F | Director | 05/03/2017 | 50,808 |
| POPS RICHARD F | Director | 05/03/2017 | 51,000 |
| Nevinny Corinne H | Director | 05/03/2017 | 50,808 |
| Nevinny Corinne H | Director | 05/03/2017 | 51,000 |
| Grigoriadis Dimitri E. | Chief Research Officer | 05/02/2017 | 550,000 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 05/02/2017 | 56,304 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 05/02/2017 | 1,157,167 |
| Gano Kyle | Chief Business Development Off | 05/01/2017 | 38,850 |
| Gano Kyle | Chief Business Development Off | 05/01/2017 | 810,000 |
| MOLLICA JOSEPH A | Director | 04/12/2017 | 67,962 |
| MOLLICA JOSEPH A | Director | 04/12/2017 | 68,000 |
| OBrien Christopher Flint | Chief Medical Officer | 04/12/2017 | 658,774 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 04/12/2017 | 658,774 |
| Lippoldt Darin | Chief Legal Officer | 04/12/2017 | 658,774 |
| Grigoriadis Dimitri E. | Chief Research Officer | 04/12/2017 | 658,774 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 04/12/2017 | 988,085 |
| Gano Kyle | Chief Business Development Off | 04/12/2017 | 658,774 |
| Bozigian Haig P. | Chief Development Officer | 04/12/2017 | 658,774 |
| LYONS GARY A | Director | 02/14/2017 | 51,000 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/06/2017 | 31,356 |
| Bozigian Haig P. | Chief Development Officer | 02/06/2017 | 41,544 |
| Gano Kyle | Chief Business Development Off | 02/06/2017 | 31,370 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/07/2017 | 5,175 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 02/06/2017 | 31,370 |
| OBrien Christopher Flint | Chief Medical Officer | 02/06/2017 | 52,063 |
| BENEVICH ERIC | Chief Commercial Officer | 02/07/2017 | 5,894 |
| BENEVICH ERIC | Chief Commercial Officer | 02/06/2017 | 35,393 |
| Lippoldt Darin | Chief Legal Officer | 02/07/2017 | 5,890 |
| Lippoldt Darin | Chief Legal Officer | 02/06/2017 | 35,410 |
| Coughlin Timothy P | Chief Financial Officer | 02/06/2017 | 41,544 |
| SHERWIN STEPHEN A | Director | 02/07/2017 | 50,968 |
| SHERWIN STEPHEN A | Director | 02/07/2017 | 51,000 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/08/2017 | 166,177 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/06/2017 | 129,972 |
| Bozigian Haig P. | Chief Development Officer | 02/03/2017 | 58,534 |
| Coughlin Timothy P | Chief Financial Officer | 02/03/2017 | 63,825 |
| Gano Kyle | Chief Business Development Off | 02/03/2017 | 58,534 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 02/03/2017 | 132,969 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/03/2017 | 58,520 |
| OBrien Christopher Flint | Chief Medical Officer | 02/03/2017 | 63,750 |
| RASTETTER WILLIAM H | Director | 02/01/2017 | 54,250 |
| RASTETTER WILLIAM H | Director | 02/01/2017 | 454,510 |
| Bozigian Haig P. | Chief Development Officer | 01/17/2017 | 66,024 |
| Coughlin Timothy P | Chief Financial Officer | 01/17/2017 | 71,138 |
| Gano Kyle | Chief Business Development Off | 01/17/2017 | 66,056 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/17/2017 | 152,438 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/17/2017 | 66,024 |
| OBrien Christopher Flint | Chief Medical Officer | 01/17/2017 | 71,155 |
| OBrien Christopher Flint | Chief Medical Officer | 01/10/2017 | 75,862 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/10/2017 | 70,509 |
| GORMAN KEVIN CHARLES | Chief Executive Officer | 01/10/2017 | 162,300 |
| Gano Kyle | Chief Business Development Off | 01/10/2017 | 54,212 |
| Coughlin Timothy P | Chief Financial Officer | 01/10/2017 | 75,897 |
| Bozigian Haig P. | Chief Development Officer | 01/10/2017 | 70,476 |
| GORMAN KEVIN CHARLES | President and CEO | 12/23/2016 | 23,569 |
| OBrien Christopher Flint | Chief Medical Officer | 11/15/2016 | 1,321,000 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 09/01/2016 | 139,050 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 09/01/2016 | 450,000 |
| OBrien Christopher Flint | Chief Medical Officer | 08/15/2016 | 609,125 |
| Nevinny Corinne H | Director | 08/08/2016 | 242,700 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 05/31/2016 | 139,050 |
| Lloyd-Smith Malcolm | Chief Regulatory Officer | 05/31/2016 | 450,000 |
| OBrien Christopher Flint | Chief Medical Officer | 05/31/2016 | 625,000 |
| POPS RICHARD F | Director | 05/25/2016 | 700,800 |
| OBrien Christopher Flint | Chief Medical Officer | 05/16/2016 | 1,125,000 |
| POPS RICHARD F | Director | 05/16/2016 | 46,005 |
| POPS RICHARD F | Director | 05/16/2016 | 46,050 |
| LYONS GARY A | Director | 05/06/2016 | 46,050 |
| Nevinny Corinne H | Director | 05/03/2016 | 46,041 |
| Nevinny Corinne H | Director | 05/03/2016 | 46,050 |
| SHERWIN STEPHEN A | Director | 04/14/2016 | 46,017 |
| SHERWIN STEPHEN A | Director | 04/14/2016 | 46,050 |
| Gano Kyle | Chief Business Development Off | 04/11/2016 | 240,595 |
| Gano Kyle | Chief Business Development Off | 04/11/2016 | 1,838,511 |
| OBrien Christopher Flint | Chief Medical Officer | 04/06/2016 | 1,125,000 |
| MOLLICA JOSEPH A | Director | 02/10/2016 | 61,368 |
| MOLLICA JOSEPH A | Director | 02/10/2016 | 61,400 |
| OBrien Christopher Flint | Chief Medical Officer | 02/03/2016 | 57,015 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/03/2016 | 52,222 |
| GORMAN KEVIN CHARLES | President and CEO | 02/03/2016 | 118,875 |
| Gano Kyle | Chief Business Development Off | 02/03/2016 | 52,222 |
| Coughlin Timothy P | Chief Financial Officer | 02/03/2016 | 57,090 |
| Bozigian Haig P. | Chief Development Officer | 02/03/2016 | 52,429 |
| OBrien Christopher Flint | Chief Medical Officer | 01/19/2016 | 81,848 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/19/2016 | 75,985 |
| GORMAN KEVIN CHARLES | President and CEO | 01/19/2016 | 175,125 |
| Gano Kyle | Chief Business Development Off | 01/19/2016 | 76,115 |
| Coughlin Timothy P | Chief Financial Officer | 01/19/2016 | 81,707 |
| Bozigian Haig P. | Chief Development Officer | 01/19/2016 | 76,001 |
| OBrien Christopher Flint | Chief Medical Officer | 01/11/2016 | 77,438 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/11/2016 | 71,841 |
| GORMAN KEVIN CHARLES | President and CEO | 01/11/2016 | 165,637 |
| Gano Kyle | Chief Business Development Off | 01/11/2016 | 55,287 |
| Coughlin Timothy P | Chief Financial Officer | 01/11/2016 | 77,438 |
| Bozigian Haig P. | Chief Development Officer | 01/11/2016 | 71,906 |
| SHERWIN STEPHEN A | Director | 04/07/2015 | 71,395 |
| SHERWIN STEPHEN A | Director | 04/07/2015 | 71,400 |
| Grigoriadis Dimitri E. | Chief Research Officer | 11/27/2015 | 57,600 |
| Grigoriadis Dimitri E. | Chief Research Officer | 11/27/2015 | 575,000 |
| Lippoldt Darin | Chief Legal Officer | 11/09/2015 | 431,262 |
| Lippoldt Darin | Chief Legal Officer | 11/09/2015 | 1,257,432 |
| OBrien Christopher Flint | Chief Medical Officer | 10/16/2015 | 1,194,500 |
| Grigoriadis Dimitri E. | Chief Research Officer | 10/16/2015 | 1,194,250 |
| GORMAN KEVIN CHARLES | President and CEO | 10/16/2015 | 1,600,295 |
| Gano Kyle | Chief Business Development Off | 10/16/2015 | 1,194,250 |
| Coughlin Timothy P | Chief Financial Officer | 10/16/2015 | 1,194,500 |
| Bozigian Haig P. | Chief Development Officer | 10/16/2015 | 1,194,500 |
| LYONS GARY A | Director | 09/18/2015 | 823,300 |
| OBrien Christopher Flint | Chief Medical Officer | 07/20/2015 | 64,800 |
| OBrien Christopher Flint | Chief Medical Officer | 07/20/2015 | 618,750 |
| Grigoriadis Dimitri E. | Chief Research Officer | 07/20/2015 | 113,161 |
| Grigoriadis Dimitri E. | Chief Research Officer | 07/20/2015 | 1,080,530 |
| Coughlin Timothy P | Chief Financial Officer | 07/20/2015 | 115,200 |
| Coughlin Timothy P | Chief Financial Officer | 07/20/2015 | 1,100,000 |
| OBrien Christopher Flint | Chief Medical Officer | 07/13/2015 | 57,600 |
| OBrien Christopher Flint | Chief Medical Officer | 07/13/2015 | 500,000 |
| Grigoriadis Dimitri E. | Chief Research Officer | 07/13/2015 | 57,600 |
| Grigoriadis Dimitri E. | Chief Research Officer | 07/13/2015 | 500,000 |
| Coughlin Timothy P | Chief Financial Officer | 07/13/2015 | 115,200 |
| Coughlin Timothy P | Chief Financial Officer | 07/13/2015 | 1,000,000 |
| MITCHELL W THOMAS | Director | 06/23/2015 | 99,900 |
| MITCHELL W THOMAS | Director | 06/23/2015 | 740,250 |
| OBrien Christopher Flint | Chief Medical Officer | 06/08/2015 | 57,600 |
| OBrien Christopher Flint | Chief Medical Officer | 06/08/2015 | 450,000 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/08/2015 | 57,600 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/08/2015 | 450,000 |
| Coughlin Timothy P | Chief Financial Officer | 06/08/2015 | 155,400 |
| Coughlin Timothy P | Chief Financial Officer | 06/08/2015 | 2,704,800 |
| Gano Kyle | See Remarks | 06/01/2015 | 172,655 |
| Gano Kyle | See Remarks | 06/01/2015 | 1,612,924 |
| OBrien Christopher Flint | Chief Medical Officer | 06/01/2015 | 57,600 |
| OBrien Christopher Flint | Chief Medical Officer | 06/01/2015 | 422,000 |
| POPS RICHARD F | Director | 05/11/2015 | 71,374 |
| POPS RICHARD F | Director | 05/11/2015 | 71,400 |
| Nevinny Corinne H | Director | 04/08/2015 | 71,385 |
| Nevinny Corinne H | Director | 04/08/2015 | 71,400 |
| NEUROCRINE BIOSCIENCES INC | Director | 04/07/2015 | 71,395 |
| NEUROCRINE BIOSCIENCES INC | Director | 04/07/2015 | 71,400 |
| Coughlin Timothy P | Chief Financial Officer | 03/20/2015 | 103,600 |
| Coughlin Timothy P | Chief Financial Officer | 03/20/2015 | 1,779,600 |
| GORMAN KEVIN CHARLES | President and CEO | 03/24/2015 | 103,600 |
| GORMAN KEVIN CHARLES | President and CEO | 03/24/2015 | 1,661,200 |
| LYONS GARY A | Director | 03/24/2015 | 1,245,900 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/23/2015 | 115,200 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/23/2015 | 800,000 |
| LYONS GARY A | Director | 02/10/2015 | 35,687 |
| LYONS GARY A | Director | 02/10/2015 | 35,700 |
| LYONS GARY A | Director | 02/10/2015 | 35,687 |
| LYONS GARY A | Director | 02/10/2015 | 35,700 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/10/2015 | 115,200 |
| Grigoriadis Dimitri E. | Chief Research Officer | 02/10/2015 | 700,000 |
| LYONS GARY A | Director | 01/20/2015 | 35,683 |
| LYONS GARY A | Director | 01/20/2015 | 35,700 |
| GORMAN KEVIN CHARLES | President and CEO | 01/16/2015 | 115,463 |
| Coughlin Timothy P | Chief Financial Officer | 01/16/2015 | 53,917 |
| OBrien Christopher Flint | Chief Medical Officer | 01/16/2015 | 53,883 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/16/2015 | 50,001 |
| Bozigian Haig P. | Chief Development Officer | 01/16/2015 | 50,034 |
| Gano Kyle | Chief Business Dev Officer | 01/16/2015 | 50,050 |
| Gano Kyle | Chief Business Dev Officer | 01/13/2015 | 96,450 |
| Gano Kyle | Chief Business Dev Officer | 01/13/2015 | 750,000 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/13/2015 | 115,200 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/13/2015 | 600,000 |
| MITCHELL W THOMAS | Director | 01/13/2015 | 202,800 |
| MITCHELL W THOMAS | Director | 01/13/2015 | 1,353,150 |
| Coughlin Timothy P | Chief Financial Officer | 01/12/2015 | 49,648 |
| Bozigian Haig P. | Chief Development Officer | 01/12/2015 | 46,231 |
| OBrien Christopher Flint | Chief Medical Officer | 01/12/2015 | 49,717 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/12/2015 | 46,117 |
| Gano Kyle | Chief Business Dev Officer | 01/12/2015 | 35,512 |
| GORMAN KEVIN CHARLES | President and CEO | 01/12/2015 | 106,613 |
| GORMAN KEVIN CHARLES | President and CEO | 01/08/2015 | 64,750 |
| GORMAN KEVIN CHARLES | President and CEO | 01/08/2015 | 684,750 |
| Coughlin Timothy P | Chief Financial Officer | 01/08/2015 | 25,900 |
| Coughlin Timothy P | Chief Financial Officer | 01/08/2015 | 272,500 |
| OBrien Christopher Flint | Chief Medical Officer | 01/08/2015 | 142,450 |
| OBrien Christopher Flint | Chief Medical Officer | 01/08/2015 | 1,496,900 |
| Bozigian Haig P. | Chief Development Officer | 01/08/2015 | 77,700 |
| Bozigian Haig P. | Chief Development Officer | 01/08/2015 | 817,200 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/08/2015 | 77,700 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/08/2015 | 820,600 |
| Bozigian Haig P. | Chief Development Officer | 01/05/2015 | 12,800 |
| Bozigian Haig P. | Chief Development Officer | 01/05/2015 | 56,900 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/05/2015 | 12,800 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/05/2015 | 56,900 |
| MITCHELL W THOMAS | Director | 01/02/2015 | 38,080 |
| MITCHELL W THOMAS | Director | 01/02/2015 | 182,320 |
| OBrien Christopher Flint | CHIEF MEDICAL OFFICER | 12/19/2014 | 51,800 |
| OBrien Christopher Flint | CHIEF MEDICAL OFFICER | 12/19/2014 | 480,400 |
| GORMAN KEVIN CHARLES | PRESIDENT AND CEO | 12/18/2014 | 295,150 |
| GORMAN KEVIN CHARLES | PRESIDENT AND CEO | 12/19/2014 | 360,150 |
| GORMAN KEVIN CHARLES | PRESIDENT AND CEO | 12/18/2014 | 1,278,200 |
| Coughlin Timothy P | Chief Financial Officer | 12/19/2014 | 25,900 |
| Coughlin Timothy P | Chief Financial Officer | 12/18/2014 | 51,800 |
| Coughlin Timothy P | Chief Financial Officer | 12/18/2014 | 463,600 |
| Coughlin Timothy P | Chief Financial Officer | 12/19/2014 | 240,200 |
| Bozigian Haig P. | Chief Development Officer | 12/17/2014 | 38,855 |
| Bozigian Haig P. | Chief Development Officer | 12/17/2014 | 337,695 |
| Grigoriadis Dimitri E. | Chief Research Officer | 12/17/2014 | 38,089 |
| Grigoriadis Dimitri E. | Chief Research Officer | 12/17/2014 | 330,885 |
| Gano Kyle | Chief Business Dev Officer | 12/17/2014 | 24,785 |
| Gano Kyle | Chief Business Dev Officer | 12/17/2014 | 111,533 |
| MOLLICA JOSEPH A | Director | 12/12/2014 | 95,196 |
| MOLLICA JOSEPH A | Director | 12/12/2014 | 95,200 |
| Bozigian Haig P. | Chief Development Officer | 12/15/2014 | 12,800 |
| Bozigian Haig P. | Chief Development Officer | 12/12/2014 | 38,545 |
| Bozigian Haig P. | Chief Development Officer | 12/15/2014 | 54,300 |
| Bozigian Haig P. | Chief Development Officer | 12/12/2014 | 224,955 |
| Grigoriadis Dimitri E. | Chief Research Officer | 12/15/2014 | 12,800 |
| Grigoriadis Dimitri E. | Chief Research Officer | 12/12/2014 | 39,311 |
| Grigoriadis Dimitri E. | Chief Research Officer | 12/15/2014 | 54,275 |
| Grigoriadis Dimitri E. | Chief Research Officer | 12/12/2014 | 231,615 |
| Gano Kyle | Chief Business Dev Officer | 12/12/2014 | 20,215 |
| Gano Kyle | Chief Business Dev Officer | 12/12/2014 | 90,968 |
| MITCHELL W THOMAS | Director | 12/10/2014 | 33,320 |
| MITCHELL W THOMAS | Director | 12/10/2014 | 153,300 |
| OBrien Christopher Flint | Chief Medical Officer | 12/11/2014 | 51,476 |
| OBrien Christopher Flint | Chief Medical Officer | 12/10/2014 | 52,124 |
| OBrien Christopher Flint | Chief Medical Officer | 12/11/2014 | 439,238 |
| OBrien Christopher Flint | Chief Medical Officer | 12/10/2014 | 433,750 |
| Coughlin Timothy P | Chief Financial Officer | 12/10/2014 | 77,100 |
| Coughlin Timothy P | Chief Financial Officer | 12/10/2014 | 429,500 |
| Coughlin Timothy P | Chief Financial Officer | 11/28/2014 | 201,400 |
| OBrien Christopher Flint | Chief Medical Officer | 11/24/2014 | 106,692 |
| OBrien Christopher Flint | Chief Medical Officer | 11/17/2014 | 220,463 |
| OBrien Christopher Flint | Chief Medical Officer | 11/13/2014 | 63,122 |
| OBrien Christopher Flint | Chief Medical Officer | 11/10/2014 | 372,400 |
| Coughlin Timothy P | Chief Financial Officer | 10/31/2014 | 190,000 |
| Coughlin Timothy P | Chief Financial Officer | 10/30/2014 | 186,200 |
| Coughlin Timothy P | Chief Financial Officer | 10/28/2014 | 180,000 |
| MITCHELL W THOMAS | Director | 10/01/2014 | 19,763 |
| LYONS GARY A | Director | 09/15/2014 | 313,200 |
| Nevinny Corinne H | Director | 05/12/2014 | 148,433 |
| Nevinny Corinne H | Director | 05/12/2014 | 148,440 |
| POPS RICHARD F | Director | 05/12/2014 | 148,433 |
| POPS RICHARD F | Director | 05/12/2014 | 148,440 |
| MOLLICA JOSEPH A | Director | 04/16/2014 | 185,539 |
| MOLLICA JOSEPH A | Director | 04/16/2014 | 185,550 |
| MITCHELL W THOMAS | Director | 04/16/2014 | 148,434 |
| MITCHELL W THOMAS | Director | 04/16/2014 | 148,440 |
| SHERWIN STEPHEN A | Director | 04/16/2014 | 148,434 |
| SHERWIN STEPHEN A | Director | 04/16/2014 | 148,440 |
| LYONS GARY A | Director | 03/07/2014 | 933,293 |
| LYONS GARY A | Director | 03/07/2014 | 933,300 |
| Bozigian Haig P. | CHIEF DEVELOPMENT OFFICER | 01/17/2014 | 77,400 |
| Bozigian Haig P. | CHIEF DEVELOPMENT OFFICER | 01/17/2014 | 500,000 |
| Grigoriadis Dimitri E. | CHIEF RESEARCH OFFICER | 01/17/2014 | 77,400 |
| Grigoriadis Dimitri E. | CHIEF RESEARCH OFFICER | 01/17/2014 | 500,000 |
| GORMAN KEVIN CHARLES | President and CEO | 01/10/2014 | 69,637 |
| Coughlin Timothy P | Chief Financial Officer | 01/10/2014 | 32,480 |
| OBrien Christopher Flint | Chief Medical Officer | 01/10/2014 | 127,462 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/10/2014 | 30,160 |
| Bozigian Haig P. | Chief Development Officer | 01/10/2014 | 30,192 |
| Gano Kyle | Chief Business Dev Officer | 01/10/2014 | 23,212 |
| GORMAN KEVIN CHARLES | President and CEO | 01/07/2014 | 1,810,080 |
| Coughlin Timothy P | Chief Financial Officer | 01/07/2014 | 1,172,500 |
| OBrien Christopher Flint | Chief Medical Officer | 01/07/2014 | 87,500 |
| Grigoriadis Dimitri E. | Chief Research Officer | 01/07/2014 | 437,500 |
| Bozigian Haig P. | Chief Development Officer | 01/07/2014 | 437,500 |
| Gano Kyle | Chief Business Dev Officer | 09/04/2013 | 37,464 |
| OBrien Christopher Flint | Chief Medical Officer | 09/03/2013 | 80,000 |
| Coughlin Timothy P | Chief Financial Officer | 08/21/2013 | 286,477 |
| Grigoriadis Dimitri E. | Chief Research Officer | 08/21/2013 | 204,635 |
| Bozigian Haig P. | Chief Development Officer | 08/21/2013 | 210,552 |
| OBrien Christopher Flint | Chief Medical Officer | 08/05/2013 | 75,000 |
| Coughlin Timothy P | Chief Financial Officer | 08/05/2013 | 164,365 |
| MITCHELL W THOMAS | Director | 08/06/2013 | 22,506 |
| Grigoriadis Dimitri E. | Chief Research Officer | 08/05/2013 | 171,064 |
| Bozigian Haig P. | Chief Development Officer | 08/05/2013 | 165,015 |
| OBrien Christopher Flint | Chief Medical Officer | 07/12/2013 | 72,500 |
| OBrien Christopher Flint | Chief Medical Officer | 06/28/2013 | 101,250 |
| OBrien Christopher Flint | Chief Medical Officer | 06/27/2013 | 50,141 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/27/2013 | 49,881 |
| Bozigian Haig P. | Chief Development Officer | 06/27/2013 | 104,000 |
| Bozigian Haig P. | Chief Development Officer | 06/24/2013 | 9,782 |
| OBrien Christopher Flint | Chief Medical Officer | 06/21/2013 | 187,861 |
| OBrien Christopher Flint | Chief Medical Officer | 06/20/2013 | 261,386 |
| Bozigian Haig P. | Chief Development Officer | 06/21/2013 | 303,375 |
| Bozigian Haig P. | Chief Development Officer | 06/20/2013 | 255,651 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/21/2013 | 328,931 |
| Grigoriadis Dimitri E. | Chief Research Officer | 06/20/2013 | 257,086 |
| Nevinny Corinne H | Director | 03/28/2013 | 127,198 |
| Nevinny Corinne H | Director | 03/28/2013 | 127,200 |
| MITCHELL W THOMAS | Director | 03/28/2013 | 127,198 |
| MITCHELL W THOMAS | Director | 03/28/2013 | 127,200 |
| POPS RICHARD F | Director | 03/28/2013 | 127,198 |
| POPS RICHARD F | Director | 03/28/2013 | 127,200 |
| SHERWIN STEPHEN A | Director | 03/28/2013 | 127,198 |
| SHERWIN STEPHEN A | Director | 03/28/2013 | 127,200 |
| MOLLICA JOSEPH A | Director | 03/28/2013 | 158,995 |
| MOLLICA JOSEPH A | Director | 03/28/2013 | 159,000 |
| MITCHELL W THOMAS | Director | 12/05/2012 | 6,669 |
| BVF PARTNERS L P/IL | 10% Owner | 10/12/2011 | 175,672 |
| BVF PARTNERS L P/IL | 10% Owner | 10/11/2011 | 21,768 |
| BVF PARTNERS L P/IL | 10% Owner | 10/10/2011 | 249,779 |
| BVF PARTNERS L P/IL | 10% Owner | 10/10/2011 | 53,644 |
| BVF PARTNERS L P/IL | 10% Owner | 10/10/2011 | 88,289 |
| GORMAN KEVIN CHARLES | President and CEO | 02/28/2011 | 105,134 |
| Coughlin Timothy P | VP and Chief Financial Officer | 02/28/2011 | 84,104 |
| VALEUR JENSEN MARGARET E | EVP and General Counsel | 02/28/2011 | 84,104 |
| OBrien Christopher Flint | Sr. VP & Chief Medical Officer | 02/28/2011 | 84,091 |
| Grigoriadis Dimitri E. | Vice President, Research | 02/28/2011 | 84,075 |
| Bozigian Haig P. | Sr Vice President, Development | 02/28/2011 | 84,085 |
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FUNDS WITH A POSITION IN NEUROCRINE BIOSCIENCES, INC.
| Fund | # Shares Owned | % of Portfolio | % Change | Investing Style |
|---|---|---|---|---|
| BLACKROCK INC. | 13,647,891 | 0.05% | 2.07% | Other |
| RENAISSANCE TECHNOLOGIES LLC | 1,988,546 | 0.41% | 25.05% | Other |
| GEODE CAPITAL MANAGEMENT, LLC | 1,623,124 | 0.02% | 4.41% | Other |
| DODGE & COX | 1,259,744 | 0.11% | 489.76% | Value |
| DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 896,719 | 2.18% | -25.87% | Other |
| AQR CAPITAL MANAGEMENT LLC | 738,852 | 0.18% | 97.57% | Other |
| ORBIMED ADVISORS LLC | 519,279 | 1.37% | 24.86% | Other |
| CANDRIAM S.C.A. | 369,899 | 0.34% | -1.95% | Other |
| BALYASNY ASSET MANAGEMENT L.P. | 219,826 | 0.05% | -54.02% | Event Driven |
| SOROS FUND MANAGEMENT LLC | 185,000 | 0.32% | 236.36% | Other |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 116,914 | 0.19% | -39.57% | Growth |
| TIG ADVISORS, LLC | 92,100 (Call) | 1.51% | New | Event Driven |
| D. E. SHAW & CO., INC. | 76,002 | 0.00875% | 28.68% | Other |
| FARALLON CAPITAL MANAGEMENT LLC | 72,398 | 0.05% | -83.84% | Event Driven, Value |
| FISHER ASSET MANAGEMENT, LLC | 60,227 | 0.0042% | -2.59% | Other |
| BRIDGEWATER ASSOCIATES, LP | 23,505 | 0.02% | -57.26% | Other |
| UBS OCONNOR LLC | 19,796 | 0.19% | -41.43% | Value |
| UBS OCONNOR LLC | 10,000 (Call) | 0.00611% | New | Value |
| GOTHAM ASSET MANAGEMENT, LLC | 5,538 | 0.01% | 9.49% | Other |
| TUDOR INVESTMENT CORP ET AL | 3,574 | 0.00379% | -92.68% | Event Driven, Other |
| ALPS ADVISORS INC | 2,915 | 0.00302% | -5.36% | Other |
| MOTLEY FOOL ASSET MANAGEMENT LLC | 1,870 | 0.02% | -8.24% | Growth At A Reasonable Price |
CHANGE IN SHARES OUTSTANDING FOR NEUROCRINE BIOSCIENCES, INC.
STOCK BUYBACKS FOR NEUROCRINE BIOSCIENCES, INC.
Period of Report
Previous Period
% Change in Shares
10-K/10-Q Filings
Quarter
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Period of Report: 12/31/2023
10-K/10-Q Filings: View
Previous Period
% Change in Shares
Quarter
09/30/2023
1.09%
1Q
06/30/2023
2.00%
2Q
03/31/2023
5.25%
3Q
12/31/2022
1.49%
4Q
09/30/2022
3.23%
5Q
06/30/2022
6.90%
6Q
03/31/2022
4.71%
7Q
12/31/2021
4.39%
8Q
09/30/2021
4.61%
9Q
06/30/2021
4.61%
10Q
03/31/2021
4.07%
11Q
12/31/2020
5.14%
12Q
09/30/2020
9.54%
13Q
06/30/2020
4.07%
14Q
03/31/2020
5.36%
15Q
12/31/2019
5.14%
16Q
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BUYBACK ANNOUNCEMENT(S) FOR NEUROCRINE BIOSCIENCES, INC.
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