Karyopharm Therapeutics Inc. (KPTI) NASDAQ
$1.28 (0.10) (-7.25%)
Market Cap: $147.29M
As of 04/18/24 04:00 PM EDT. Market closed.
Karyopharm Therapeutics Inc. (KPTI)
NASDAQ
$1.28
(0.10) (-7.25%)
Market Cap: $147.29M
As of 04/18/24 04:00 PM EDT. Market closed.
Add to Portfolio
karyopharm therapeutics inc. is a clinical-stage pharmaceutical company focused on discovery and development of novel first-in-class drugs directed against nuclear transport targets for the treatment of cancer and other major diseases. for more information, please visit ... read more
karyopharm therapeutics inc. is a clinical-stage pharmaceutical company focused on discovery and development of novel first-in-class drugs directed against nuclear transport targets for the treatment of cancer and other major diseases. for more information, please visit www.karyopharm.com read less
COMPANY PROFILE
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
Michael Kauffman
Full Time Employees
506
CEO Compensation (Base)
$550,000
CEO Compensation (Total)
$2.27M
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
Michael Kauffman
Full Time Employees
506
CEO Compensation (Base)
$550,000
CEO Compensation (Total)
$2.27M
Address
85 Wells Ave, Massachusetts, Newton Center, 02459-3298.
PRICE CHART FOR KARYOPHARM THERAPEUTICS INC
From:
To:
NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
-
Previous Close
$1.38
Days Range
$1.23 - $1.42
52 week range
$0.62 - $4.11
Volume
701
Avg. Volume (30 days)
1,131,947
Market Cap
$147.29M
Dividend Yield
-
P/E
(1.03)
Shares Outstanding
115,067,083
Open
-
Previous Close
$1.38
Days Range
$1.23 - $1.42
52 week range
$0.62 - $4.11
Volume
701
Avg. Volume (30 days)
1,131,947
Market Cap
$147.29M
Dividend Yield
-
P/E
(1.03)
Shares Outstanding
115,067,083
FINANCIAL STATEMENTS FOR KARYOPHARM THERAPEUTICS INC
LOADING...
Open in: 
Open in:
INSIDER TRANSACTIONS FOR KARYOPHARM THERAPEUTICS INC
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| Paulson Richard A. | President and CEO | Apr 04, 2024 | Sale | $1.29 | 3,563 | 4,596 | 1,157,273 | Apr 05, 2024, 05:20 PM |
| Paulson Richard A. | President and CEO | Mar 05, 2024 | Sale | $1.30 | 3,573 | 4,645 | 1,160,836 | Mar 06, 2024, 04:14 PM |
| Rangwala Reshma | EVP & Chief Medical Officer | Mar 01, 2024 | Sale | $1.20 | 5,969 | 7,163 | 349,720 | Mar 04, 2024, 07:41 PM |
| Rangwala Reshma | EVP & Chief Medical Officer | Feb 29, 2024 | Sale | $1.17 | 15,667 | 18,330 | 355,689 | Mar 04, 2024, 07:41 PM |
| Poulton Stuart | EVP, Chief Development Officer | Mar 01, 2024 | Sale | $1.20 | 6,155 | 7,386 | 329,511 | Mar 04, 2024, 07:40 PM |
| Poulton Stuart | EVP, Chief Development Officer | Feb 29, 2024 | Sale | $1.17 | 16,311 | 19,084 | 335,666 | Mar 04, 2024, 07:40 PM |
| Mason Michael | EVP, CFO & Treasurer | Mar 01, 2024 | Sale | $1.20 | 6,162 | 7,394 | 398,756 | Mar 04, 2024, 07:39 PM |
| Mason Michael | EVP, CFO & Treasurer | Feb 29, 2024 | Sale | $1.17 | 27,687 | 32,394 | 404,918 | Mar 04, 2024, 07:39 PM |
| Mano Michael | SVP, General Counsel&Secretary | Mar 01, 2024 | Sale | $1.20 | 3,576 | 4,291 | 277,852 | Mar 04, 2024, 07:38 PM |
| Mano Michael | SVP, General Counsel&Secretary | Feb 29, 2024 | Sale | $1.17 | 16,973 | 19,858 | 281,428 | Mar 04, 2024, 07:38 PM |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Mar 01, 2024 | Sale | $1.20 | 5,109 | 6,131 | 393,509 | Mar 04, 2024, 07:37 PM |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Feb 29, 2024 | Sale | $1.17 | 21,840 | 25,553 | 398,618 | Mar 04, 2024, 07:37 PM |
| Paulson Richard A. | President and CEO | Mar 01, 2024 | Sale | $1.20 | 19,374 | 23,249 | 1,164,409 | Mar 04, 2024, 07:36 PM |
| Paulson Richard A. | President and CEO | Feb 29, 2024 | Sale | $1.17 | 80,470 | 94,150 | 1,183,783 | Mar 04, 2024, 07:36 PM |
| Mason Michael | EVP, CFO & Treasurer | Feb 27, 2024 | Sale | $1.32 | 2,545 | 3,369 | 244,400 | Feb 29, 2024, 05:35 PM |
| Poulton Stuart | EVP, Chief Development Officer | Feb 15, 2024 | Sale | $1.33 | 5,847 | 7,783 | 163,871 | Feb 20, 2024, 04:59 PM |
| Mason Michael | EVP, CFO & Treasurer | Feb 06, 2024 | Sale | $1.59 | 4,205 | 6,671 | 246,945 | Feb 08, 2024, 04:36 PM |
| Paulson Richard A. | President and CEO | Feb 06, 2024 | Sale | $1.59 | 4,012 | 6,365 | 821,453 | Feb 08, 2024, 04:34 PM |
| Paulson Richard A. | President and CEO | Jan 04, 2024 | Sale | $0.82 | 4,114 | 3,373 | 783,465 | Jan 08, 2024, 09:00 PM |
| Paulson Richard A. | President and CEO | Dec 04, 2023 | Sale | $0.79 | 3,622 | 2,861 | 787,579 | Dec 05, 2023, 05:03 PM |
| Paulson Richard A. | President and CEO | Nov 06, 2023 | Sale | $0.92 | 3,606 | 3,319 | 791,201 | Nov 07, 2023, 05:32 PM |
| Paulson Richard A. | President and CEO | Oct 04, 2023 | Sale | $1.27 | 3,589 | 4,558 | 794,807 | Oct 05, 2023, 04:46 PM |
| BOHLIN GAREN G | Director | Sep 12, 2023 | Buy | $1.22 | 41,140 | 49,985 | 45,140 | Sep 12, 2023, 04:07 PM |
| Paulson Richard A. | President and CEO | Sep 05, 2023 | Sale | $1.33 | 3,622 | 4,817 | 798,460 | Sep 06, 2023, 04:06 PM |
| Mason Michael | EVP, CFO & Treasurer | Sep 01, 2023 | Sale | $1.33 | 6,913 | 9,203 | 237,817 | Sep 05, 2023, 04:30 PM |
| Mano Michael | SVP, General Counsel&Secretary | Sep 01, 2023 | Sale | $1.33 | 3,888 | 5,176 | 142,234 | Sep 05, 2023, 04:29 PM |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sep 01, 2023 | Sale | $1.33 | 7,415 | 9,872 | 204,086 | Sep 05, 2023, 04:27 PM |
| Paulson Richard A. | President and CEO | Aug 07, 2023 | Sale | $1.72 | 3,722 | 6,402 | 802,018 | Aug 08, 2023, 05:02 PM |
| Poulton Stuart | EVP, Chief Development Officer | Jul 28, 2023 | Sale | $1.70 | 2,845 | 4,837 | 156,286 | Aug 01, 2023, 05:37 PM |
| Paulson Richard A. | President and CEO | Jul 05, 2023 | Sale | $1.72 | 3,538 | 6,085 | 805,740 | Jul 06, 2023, 05:36 PM |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Jun 08, 2023 | Sale | $2.35 | 1,839 | 4,322 | 211,501 | Jun 12, 2023, 04:07 PM |
| Paulson Richard A. | President and CEO | Jun 05, 2023 | Sale | $2.24 | 3,536 | 7,922 | 809,278 | Jun 07, 2023, 04:11 PM |
| Mason Michael | EVP, CFO & Treasurer | Jun 02, 2023 | Sale | $2.22 | 631 | 1,401 | 244,730 | Jun 05, 2023, 04:10 PM |
| Paulson Richard A. | President and CEO | May 04, 2023 | Sale | $3.35 | 3,805 | 12,753 | 812,814 | May 05, 2023, 05:06 PM |
| Rangwala Reshma | EVP & Chief Medical Officer | Apr 20, 2023 | Sale | $4.05 | 6,770 | 27,416 | 164,885 | Apr 24, 2023, 06:09 PM |
| Paulson Richard A. | President and CEO | Apr 04, 2023 | Sale | $3.97 | 3,497 | 13,883 | 816,619 | Apr 05, 2023, 05:06 PM |
| Paulson Richard A. | President and CEO | Mar 06, 2023 | Sale | $3.16 | 3,506 | 11,079 | 820,116 | Mar 07, 2023, 04:06 PM |
| Mitchener Stephen | SVP, Chief Business Officer | Mar 01, 2023 | Sale | $3.03 | 6,357 | 19,257 | 128,313 | Mar 02, 2023, 05:36 PM |
| Mano Michael | SVP, General Counsel&Secretary | Mar 01, 2023 | Sale | $3.03 | 6,878 | 20,835 | 146,122 | Mar 02, 2023, 05:35 PM |
| Mano Michael | SVP, General Counsel&Secretary | Mar 01, 2023 | Sale | $3.03 | 6,878 | 20,835 | 146,122 | Mar 02, 2023, 05:35 PM |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Mar 01, 2023 | Sale | $3.03 | 11,239 | 34,045 | 210,687 | Mar 02, 2023, 05:33 PM |
| Mason Michael | EVP, CFO & Treasurer | Mar 01, 2023 | Sale | $3.03 | 11,205 | 33,942 | 245,361 | Mar 02, 2023, 05:30 PM |
| Paulson Richard A. | President and CEO | Mar 01, 2023 | Sale | $3.03 | 33,033 | 100,064 | 823,622 | Mar 02, 2023, 05:28 PM |
| Poulton Stuart | EVP, Chief Development Officer | Feb 15, 2023 | Sale | $3.19 | 5,869 | 18,717 | 64,335 | Feb 17, 2023, 04:07 PM |
| Mason Michael | EVP, CFO & Treasurer | Feb 06, 2023 | Sale | $3.40 | 4,141 | 14,079 | 164,368 | Feb 08, 2023, 04:11 PM |
| Paulson Richard A. | President and CEO | Feb 06, 2023 | Sale | $3.40 | 3,950 | 13,430 | 604,655 | Feb 08, 2023, 04:09 PM |
| Paulson Richard A. | President and CEO | Jan 04, 2023 | Sale | $3.27 | 3,922 | 12,825 | 608,605 | Jan 05, 2023, 06:16 PM |
| Paulson Richard A. | President and CEO | Dec 05, 2022 | Sale | $5.17 | 3,490 | 18,043 | 612,527 | Dec 06, 2022, 05:00 PM |
| Paulson Richard A. | President and CEO | Nov 04, 2022 | Sale | $4.54 | 3,493 | 15,858 | 616,017 | Nov 08, 2022, 06:19 PM |
| Paulson Richard A. | President and CEO | Oct 04, 2022 | Sale | $5.87 | 3,488 | 20,475 | 619,510 | Oct 05, 2022, 04:12 PM |
| Paulson Richard A. | President and CEO | Sep 08, 2022 | Sale | $5.23 | 3,479 | 18,196 | 626,461 | Sep 09, 2022, 08:17 AM |
| Greene Barry E | Director | Aug 11, 2022 | Option Exercise | $1.49 | 7,576 | 11,250 | 13,606 | Aug 15, 2022, 08:05 AM |
| Paulson Richard A. | President and CEO | Aug 04, 2022 | Sale | $4.48 | 2,314 | 10,367 | 626,477 | Aug 05, 2022, 04:08 PM |
| Paulson Richard A. | President and CEO | Jul 08, 2022 | Sale | $5.18 | 2,115 | 10,948 | 628,791 | Jul 11, 2022, 04:18 PM |
| Cheng Sohanya Roshan | Chief Commercial Officer | Jun 13, 2022 | Sale | $5.21 | 1,551 | 8,075 | 91,434 | Jun 14, 2022, 07:25 PM |
| PAKIANATHAN DEEPIKA | Director | Jun 10, 2022 | Sale | $6.00 | 1,307 | 7,844 | 1,707,549 | Jun 10, 2022, 05:20 PM |
| PAKIANATHAN DEEPIKA | Director | Jun 09, 2022 | Sale | $6.18 | 211,500 | 1,307,028 | 1,708,843 | Jun 10, 2022, 05:20 PM |
| PAKIANATHAN DEEPIKA | Director | Jun 08, 2022 | Sale | $6.50 | 325,977 | 2,119,926 | 1,918,298 | Jun 10, 2022, 05:20 PM |
| Paulson Richard A. | President and CEO | Jun 07, 2022 | Sale | $5.76 | 2,542 | 14,642 | 630,906 | Jun 08, 2022, 04:23 PM |
| Mason Michael | EVP, CFO, Treasurer | Jun 03, 2022 | Sale | $6.04 | 601 | 3,630 | 138,512 | Jun 06, 2022, 05:40 PM |
| Frenkel Ran | EVP, Chief Dev. Officer | Feb 28, 2022 | Sale | $10.24 | 1,663 | 17,025 | 168,290 | Mar 02, 2022, 03:34 PM |
| Mason Michael | EVP, CFO & Treasurer | Feb 28, 2022 | Sale | $10.24 | 2,398 | 24,550 | 139,110 | Mar 02, 2022, 03:33 PM |
| Shacham Sharon | Chief Scientific Officer | Feb 28, 2022 | Sale | $10.24 | 6,226 | 63,739 | 713,757 | Mar 02, 2022, 03:20 PM |
| Shacham Sharon | Chief Scientific Officer | Feb 28, 2022 | Sale | $10.24 | 6,226 | 63,739 | 898,131 | Mar 02, 2022, 03:20 PM |
| Shah Jatin | EVP, Chief Medical Officer | Feb 17, 2022 | Sale | $12.12 | 1,306 | 15,833 | 129,450 | Feb 22, 2022, 04:19 PM |
| Frenkel Ran | EVP, Chief Dev. Officer | Feb 17, 2022 | Sale | $12.12 | 2,929 | 35,509 | 101,703 | Feb 22, 2022, 04:16 PM |
| Shacham Sharon | Chief Scientific Officer | Feb 17, 2022 | Sale | $12.12 | 9,088 | 110,177 | 904,357 | Feb 22, 2022, 04:15 PM |
| Shacham Sharon | Chief Scientific Officer | Feb 17, 2022 | Sale | $12.12 | 9,079 | 110,068 | 698,983 | Feb 22, 2022, 04:15 PM |
| Kauffman Michael | Director | Feb 17, 2022 | Sale | $12.12 | 9,088 | 110,177 | 904,357 | Feb 22, 2022, 04:14 PM |
| Kauffman Michael | Director | Feb 17, 2022 | Sale | $12.12 | 9,079 | 110,068 | 698,983 | Feb 22, 2022, 04:14 PM |
| Shah Jatin | EVP, Chief Medical Officer | Feb 07, 2022 | Sale | $9.86 | 1,704 | 16,805 | 130,756 | Feb 09, 2022, 05:27 PM |
| Frenkel Ran | EVP, Chief Dev. Officer | Feb 07, 2022 | Sale | $9.86 | 1,991 | 19,635 | 104,632 | Feb 09, 2022, 05:26 PM |
| Mason Michael | EVP, CFO & Treasurer | Feb 07, 2022 | Sale | $9.86 | 3,947 | 38,925 | 53,308 | Feb 09, 2022, 05:25 PM |
| Kauffman Michael | Director | Feb 07, 2022 | Sale | $9.86 | 6,764 | 66,707 | 708,062 | Feb 09, 2022, 05:24 PM |
| Kauffman Michael | Director | Feb 07, 2022 | Sale | $9.86 | 6,707 | 66,144 | 913,445 | Feb 09, 2022, 05:24 PM |
| Shacham Sharon | Chief Scientific Officer | Feb 07, 2022 | Sale | $9.86 | 6,764 | 66,707 | 708,062 | Feb 09, 2022, 05:22 PM |
| Shacham Sharon | Chief Scientific Officer | Feb 07, 2022 | Sale | $9.86 | 6,707 | 66,144 | 913,445 | Feb 09, 2022, 05:22 PM |
| Mitchener Stephen | SVP, Chief Business Officer | Dec 02, 2021 | Sale | $6.69 | 499 | 3,338 | 3,296 | Dec 03, 2021, 06:17 PM |
| Shah Jatin | EVP, Chief Medical Officer | Jul 12, 2021 | Option Exercise | $9.73 | 665 | 6,470 | 131,137 | Jul 13, 2021, 06:21 PM |
| Shah Jatin | EVP, Chief Medical Officer | May 07, 2021 | Buy | $8.60 | 23,250 | 199,992 | 131,802 | May 11, 2021, 08:58 AM |
| Shacham Sharon | President & CSO | Mar 18, 2021 | Sale | $12.39 | 4,000 | 49,553 | 714,826 | Mar 23, 2021, 07:50 AM |
| Kauffman Michael | Chief Executive Officer | Mar 18, 2021 | Sale | $12.39 | 4,000 | 49,553 | 714,826 | Mar 23, 2021, 07:48 AM |
| Shah Jatin | EVP, Chief Medical Officer | Feb 18, 2021 | Sale | $14.83 | 1,186 | 17,590 | 51,791 | Feb 22, 2021, 08:12 PM |
| Frenkel Ran | EVP, Chief Dev. Officer | Feb 18, 2021 | Sale | $14.83 | 2,887 | 42,818 | 46,126 | Feb 22, 2021, 08:11 PM |
| Shacham Sharon | President & CSO | Feb 18, 2021 | Sale | $14.83 | 9,495 | 140,822 | 575,126 | Feb 22, 2021, 08:10 PM |
| Shacham Sharon | President & CSO | Feb 18, 2021 | Sale | $14.83 | 9,495 | 140,822 | 776,452 | Feb 22, 2021, 08:10 PM |
| Kauffman Michael | Chief Executive Officer | Feb 18, 2021 | Sale | $14.83 | 9,495 | 140,822 | 575,126 | Feb 22, 2021, 08:09 PM |
| Kauffman Michael | Chief Executive Officer | Feb 18, 2021 | Sale | $14.83 | 9,495 | 140,822 | 776,452 | Feb 22, 2021, 08:09 PM |
| Lewis Tanya | EVP, Chief Reg. Affairs | Feb 11, 2021 | Sale | $15.52 | 2,046 | 31,752 | 4,143 | Feb 17, 2021, 06:49 PM |
| Shah Jatin | EVP, Chief Medical Officer | Feb 11, 2021 | Sale | $15.52 | 1,748 | 27,127 | 48,127 | Feb 17, 2021, 06:48 PM |
| Frenkel Ran | EVP, Chief Dev. Officer | Feb 11, 2021 | Sale | $15.52 | 2,046 | 31,752 | 39,338 | Feb 17, 2021, 06:47 PM |
| Mason Michael | SVP, CFO & Treasurer | Feb 11, 2021 | Sale | $15.52 | 2,858 | 44,354 | 5,292 | Feb 17, 2021, 06:46 PM |
| Shacham Sharon | President & CSO | Feb 11, 2021 | Sale | $15.52 | 6,601 | 102,441 | 562,821 | Feb 17, 2021, 06:45 PM |
| Shacham Sharon | President & CSO | Feb 11, 2021 | Sale | $15.52 | 6,642 | 103,077 | 764,147 | Feb 17, 2021, 06:45 PM |
| Kauffman Michael | Chief Executive Officer | Feb 11, 2021 | Sale | $15.52 | 6,642 | 103,077 | 764,147 | Feb 17, 2021, 06:44 PM |
| Kauffman Michael | Chief Executive Officer | Feb 11, 2021 | Sale | $15.52 | 6,601 | 102,441 | 562,821 | Feb 17, 2021, 06:44 PM |
| Mirza Mansoor Raza | Director | Dec 18, 2020 | Option Exercise | $5.43 | 5,000 | 27,150 | 5,000 | Dec 22, 2020, 06:16 PM |
| Mirza Mansoor Raza | Director | Dec 18, 2020 | Sale | $18.00 | 5,000 | 90,000 | 0 | Dec 22, 2020, 06:16 PM |
| Mirza Mansoor Raza | Director | Dec 07, 2020 | Option Exercise | $5.43 | 20,000 | 108,600 | 20,000 | Dec 08, 2020, 05:14 PM |
| Mirza Mansoor Raza | Director | Dec 07, 2020 | Sale | $16.07 | 20,000 | 321,383 | 15,000 | Dec 08, 2020, 05:14 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Dec 01, 2020 | Option Exercise | $10.42 | 137,061 | 1,428,751 | 82,647 | Dec 03, 2020, 05:17 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Dec 01, 2020 | Sale | $17.53 | 137,061 | 2,402,227 | 4,523 | Dec 03, 2020, 05:17 PM |
| Lewis Tanya | EVP,Chief Reg.&Quality Officer | Oct 30, 2020 | Sale | $15.58 | 226 | 3,521 | 539 | Nov 04, 2020, 08:18 PM |
| Shah Jatin | EVP, Chief Medical Officer | Jul 15, 2020 | Sale | $19.46 | 589 | 11,462 | 43,229 | Nov 04, 2020, 08:16 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Nov 02, 2020 | Sale | $14.92 | 772 | 11,518 | 4,523 | Nov 04, 2020, 04:09 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Oct 13, 2020 | Option Exercise | $9.23 | 39,271 | 362,537 | 43,199 | Oct 14, 2020, 06:00 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Oct 13, 2020 | Sale | $16.86 | 39,271 | 661,969 | 4,649 | Oct 14, 2020, 06:00 PM |
| Kauffman Michael | Chief Executive Officer | Oct 12, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,989 | Oct 14, 2020, 05:56 PM |
| Kauffman Michael | Chief Executive Officer | Oct 12, 2020 | Sale | $14.89 | 7,500 | 111,682 | 756,489 | Oct 14, 2020, 05:56 PM |
| Shacham Sharon | President & CSO | Oct 12, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,989 | Oct 14, 2020, 05:54 PM |
| Shacham Sharon | President & CSO | Oct 12, 2020 | Sale | $14.89 | 7,500 | 111,682 | 756,489 | Oct 14, 2020, 05:54 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Sep 08, 2020 | Option Exercise | $6.54 | 10,054 | 65,753 | 14,703 | Sep 10, 2020, 08:49 AM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Sep 08, 2020 | Sale | $14.98 | 10,054 | 150,609 | 4,649 | Sep 10, 2020, 08:49 AM |
| DEMAREE JOHN | Chief Commercial Officer | Aug 26, 2020 | Buy | $14.53 | 7,500 | 109,012 | 7,500 | Aug 27, 2020, 04:00 PM |
| Kauffman Michael | Chief Executive Officer | Aug 17, 2020 | Option Exercise | $0.03 | 1,477 | 49 | 757,966 | Aug 18, 2020, 06:07 PM |
| Kauffman Michael | Chief Executive Officer | Aug 17, 2020 | Sale | $15.00 | 1,477 | 22,155 | 756,489 | Aug 18, 2020, 06:07 PM |
| Shacham Sharon | President & CSO | Aug 17, 2020 | Option Exercise | $0.03 | 1,477 | 49 | 757,966 | Aug 18, 2020, 06:05 PM |
| Shacham Sharon | President & CSO | Aug 17, 2020 | Sale | $15.00 | 1,477 | 22,155 | 756,489 | Aug 18, 2020, 06:05 PM |
| Kauffman Michael | Chief Executive Officer | Jul 15, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,989 | Jul 17, 2020, 04:26 PM |
| Kauffman Michael | Chief Executive Officer | Jul 15, 2020 | Sale | $19.43 | 7,500 | 145,723 | 756,489 | Jul 17, 2020, 04:26 PM |
| Shacham Sharon | President & CSO | Jul 15, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,989 | Jul 17, 2020, 04:24 PM |
| Shacham Sharon | President & CSO | Jul 15, 2020 | Sale | $19.43 | 7,500 | 145,723 | 756,489 | Jul 17, 2020, 04:24 PM |
| Kauffman Michael | Chief Executive Officer | Jul 09, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 763,989 | Jul 13, 2020, 06:45 PM |
| Kauffman Michael | Chief Executive Officer | Jul 10, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 562,622 | Jul 13, 2020, 06:45 PM |
| Kauffman Michael | Chief Executive Officer | Jul 09, 2020 | Sale | $19.53 | 7,500 | 146,487 | 756,489 | Jul 13, 2020, 06:45 PM |
| Kauffman Michael | Chief Executive Officer | Jul 10, 2020 | Sale | $19.01 | 7,500 | 142,539 | 555,422 | Jul 13, 2020, 06:45 PM |
| Shacham Sharon | President & CSO | Jul 10, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 562,622 | Jul 13, 2020, 06:43 PM |
| Shacham Sharon | President & CSO | Jul 09, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 763,989 | Jul 13, 2020, 06:43 PM |
| Shacham Sharon | President & CSO | Jul 10, 2020 | Sale | $19.01 | 7,500 | 142,539 | 555,422 | Jul 13, 2020, 06:43 PM |
| Shacham Sharon | President & CSO | Jul 09, 2020 | Sale | $19.53 | 7,500 | 146,487 | 756,489 | Jul 13, 2020, 06:43 PM |
| Kauffman Michael | Chief Executive Officer | Jun 22, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,989 | Jun 24, 2020, 04:07 PM |
| Kauffman Michael | Chief Executive Officer | Jun 22, 2020 | Sale | $20.00 | 7,500 | 150,000 | 756,489 | Jun 24, 2020, 04:07 PM |
| Shacham Sharon | President & CSO | Jun 22, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,989 | Jun 24, 2020, 04:05 PM |
| Shacham Sharon | President & CSO | Jun 22, 2020 | Sale | $20.00 | 7,500 | 150,000 | 756,489 | Jun 24, 2020, 04:05 PM |
| Kauffman Michael | Chief Executive Officer | Jun 15, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,632 | Jun 17, 2020, 04:07 PM |
| Kauffman Michael | Chief Executive Officer | Jun 15, 2020 | Sale | $16.37 | 7,500 | 122,779 | 756,489 | Jun 17, 2020, 04:07 PM |
| Shacham Sharon | President & CSO | Jun 15, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,632 | Jun 17, 2020, 04:05 PM |
| Shacham Sharon | President & CSO | Jun 15, 2020 | Sale | $16.37 | 7,500 | 122,779 | 756,489 | Jun 17, 2020, 04:05 PM |
| Kauffman Michael | Chief Executive Officer | Jun 09, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 763,989 | Jun 11, 2020, 04:39 PM |
| Kauffman Michael | Chief Executive Officer | Jun 10, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 562,622 | Jun 11, 2020, 04:39 PM |
| Kauffman Michael | Chief Executive Officer | Jun 10, 2020 | Sale | $18.13 | 7,500 | 135,944 | 555,122 | Jun 11, 2020, 04:39 PM |
| Kauffman Michael | Chief Executive Officer | Jun 09, 2020 | Sale | $18.50 | 7,500 | 138,745 | 756,489 | Jun 11, 2020, 04:39 PM |
| Shacham Sharon | President & CSO | Jun 10, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 562,622 | Jun 11, 2020, 04:36 PM |
| Shacham Sharon | President & CSO | Jun 09, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 763,989 | Jun 11, 2020, 04:36 PM |
| Shacham Sharon | President & CSO | Jun 10, 2020 | Sale | $18.13 | 7,500 | 135,944 | 555,122 | Jun 11, 2020, 04:36 PM |
| Shacham Sharon | President & CSO | Jun 09, 2020 | Sale | $18.50 | 7,500 | 138,745 | 756,489 | Jun 11, 2020, 04:36 PM |
| Kauffman Michael | Chief Executive Officer | May 18, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,989 | May 19, 2020, 05:36 PM |
| Kauffman Michael | Chief Executive Officer | May 15, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,989 | May 19, 2020, 05:36 PM |
| Kauffman Michael | Chief Executive Officer | May 18, 2020 | Sale | $20.00 | 7,500 | 150,000 | 756,489 | May 19, 2020, 05:36 PM |
| Kauffman Michael | Chief Executive Officer | May 15, 2020 | Sale | $18.65 | 7,500 | 139,840 | 756,489 | May 19, 2020, 05:36 PM |
| Shacham Sharon | President & CSO | May 15, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,989 | May 19, 2020, 05:34 PM |
| Shacham Sharon | President & CSO | May 18, 2020 | Option Exercise | $0.03 | 7,500 | 247 | 763,989 | May 19, 2020, 05:34 PM |
| Shacham Sharon | President & CSO | May 15, 2020 | Sale | $18.65 | 7,500 | 139,840 | 756,489 | May 19, 2020, 05:34 PM |
| Shacham Sharon | President & CSO | May 18, 2020 | Sale | $20.00 | 7,500 | 150,000 | 756,489 | May 19, 2020, 05:34 PM |
| Frenkel Ran | Chief Dev Operations Officer | May 07, 2020 | Sale | $20.00 | 1,974 | 39,480 | 35,088 | May 11, 2020, 04:26 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | May 07, 2020 | Option Exercise | $6.54 | 2,946 | 19,267 | 7,595 | May 11, 2020, 04:25 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | May 07, 2020 | Sale | $19.73 | 9,660 | 190,627 | 4,649 | May 11, 2020, 04:25 PM |
| Shacham Sharon | President & CSO | May 07, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 562,622 | May 11, 2020, 04:22 PM |
| Shacham Sharon | President & CSO | May 07, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 763,989 | May 11, 2020, 04:22 PM |
| Shacham Sharon | President & CSO | May 07, 2020 | Sale | $19.63 | 7,500 | 147,205 | 756,489 | May 11, 2020, 04:22 PM |
| Shacham Sharon | President & CSO | May 07, 2020 | Sale | $19.63 | 7,500 | 147,209 | 555,122 | May 11, 2020, 04:22 PM |
| Kauffman Michael | Chief Executive Officer | May 07, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 763,989 | May 11, 2020, 04:19 PM |
| Kauffman Michael | Chief Executive Officer | May 07, 2020 | Option Exercise | $4.75 | 7,500 | 35,640 | 562,622 | May 11, 2020, 04:19 PM |
| Kauffman Michael | Chief Executive Officer | May 07, 2020 | Sale | $19.63 | 7,500 | 147,205 | 756,489 | May 11, 2020, 04:19 PM |
| Kauffman Michael | Chief Executive Officer | May 07, 2020 | Sale | $19.63 | 7,500 | 147,209 | 555,122 | May 11, 2020, 04:19 PM |
| Kauffman Michael | Chief Executive Officer | Apr 08, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 766,489 | Apr 10, 2020, 05:09 PM |
| Kauffman Michael | Chief Executive Officer | Apr 09, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 565,122 | Apr 10, 2020, 05:09 PM |
| Kauffman Michael | Chief Executive Officer | Apr 08, 2020 | Sale | $18.61 | 10,000 | 186,115 | 756,489 | Apr 10, 2020, 05:09 PM |
| Kauffman Michael | Chief Executive Officer | Apr 09, 2020 | Sale | $20.64 | 10,000 | 206,404 | 555,122 | Apr 10, 2020, 05:09 PM |
| Shacham Sharon | President & CSO | Apr 08, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 766,489 | Apr 10, 2020, 05:06 PM |
| Shacham Sharon | President & CSO | Apr 09, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 565,122 | Apr 10, 2020, 05:06 PM |
| Shacham Sharon | President & CSO | Apr 08, 2020 | Sale | $18.61 | 10,000 | 186,115 | 756,489 | Apr 10, 2020, 05:06 PM |
| Shacham Sharon | President & CSO | Apr 09, 2020 | Sale | $20.64 | 10,000 | 206,404 | 555,122 | Apr 10, 2020, 05:06 PM |
| Greene Barry E | Director | Mar 13, 2020 | Option Exercise | $0.03 | 3,030 | 100 | 6,030 | Mar 17, 2020, 05:35 PM |
| Shacham Sharon | President & CSO | Mar 10, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 565,122 | Mar 11, 2020, 07:10 PM |
| Shacham Sharon | President & CSO | Mar 09, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 766,489 | Mar 11, 2020, 07:10 PM |
| Shacham Sharon | President & CSO | Mar 10, 2020 | Sale | $22.22 | 10,000 | 222,186 | 557,190 | Mar 11, 2020, 07:10 PM |
| Shacham Sharon | President & CSO | Mar 09, 2020 | Sale | $22.52 | 10,000 | 225,195 | 759,489 | Mar 11, 2020, 07:10 PM |
| Kauffman Michael | Chief Executive Officer | Mar 09, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 766,489 | Mar 11, 2020, 07:07 PM |
| Kauffman Michael | Chief Executive Officer | Mar 10, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 565,122 | Mar 11, 2020, 07:07 PM |
| Kauffman Michael | Chief Executive Officer | Mar 09, 2020 | Sale | $22.52 | 10,000 | 225,195 | 759,489 | Mar 11, 2020, 07:07 PM |
| Kauffman Michael | Chief Executive Officer | Mar 10, 2020 | Sale | $22.22 | 10,000 | 222,186 | 557,190 | Mar 11, 2020, 07:07 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Mar 02, 2020 | Option Exercise | $10.39 | 26,500 | 275,335 | 36,867 | Mar 04, 2020, 08:33 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Mar 02, 2020 | Sale | $25.37 | 26,500 | 672,279 | 29,367 | Mar 04, 2020, 08:33 PM |
| Mirza Mansoor Raza | Director | Mar 02, 2020 | Option Exercise | $8.06 | 5,000 | 40,300 | 5,000 | Mar 04, 2020, 06:51 PM |
| Mirza Mansoor Raza | Director | Mar 02, 2020 | Sale | $23.50 | 5,000 | 117,500 | 0 | Mar 04, 2020, 06:51 PM |
| Shah Jatin | EVP, Chief Medical Officer | Feb 19, 2020 | Sale | $16.48 | 1,375 | 22,663 | 40,759 | Feb 21, 2020, 05:58 PM |
| Frenkel Ran | Chief Dev Operations Officer | Feb 19, 2020 | Sale | $16.48 | 2,975 | 49,034 | 36,066 | Feb 21, 2020, 05:57 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Feb 19, 2020 | Sale | $16.48 | 2,961 | 48,803 | 10,367 | Feb 21, 2020, 05:55 PM |
| Shacham Sharon | President & CSO | Feb 19, 2020 | Sale | $16.48 | 8,817 | 145,321 | 756,489 | Feb 21, 2020, 05:54 PM |
| Shacham Sharon | President & CSO | Feb 19, 2020 | Sale | $16.48 | 8,817 | 145,321 | 555,122 | Feb 21, 2020, 05:54 PM |
| Kauffman Michael | Chief Executive Officer | Feb 19, 2020 | Sale | $16.48 | 8,817 | 145,321 | 756,489 | Feb 21, 2020, 05:53 PM |
| Kauffman Michael | Chief Executive Officer | Feb 19, 2020 | Sale | $16.48 | 8,817 | 145,321 | 555,122 | Feb 21, 2020, 05:53 PM |
| Shacham Sharon | President & CSO | Feb 11, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 552,139 | Feb 12, 2020, 04:21 PM |
| Shacham Sharon | President & CSO | Feb 10, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 753,506 | Feb 12, 2020, 04:21 PM |
| Shacham Sharon | President & CSO | Feb 11, 2020 | Sale | $17.43 | 10,000 | 174,294 | 542,139 | Feb 12, 2020, 04:21 PM |
| Shacham Sharon | President & CSO | Feb 10, 2020 | Sale | $16.93 | 10,000 | 169,327 | 743,506 | Feb 12, 2020, 04:21 PM |
| Kauffman Michael | Chief Executive Officer | Feb 10, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 753,506 | Feb 12, 2020, 04:20 PM |
| Kauffman Michael | Chief Executive Officer | Feb 11, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 552,139 | Feb 12, 2020, 04:20 PM |
| Kauffman Michael | Chief Executive Officer | Feb 11, 2020 | Sale | $17.43 | 10,000 | 174,294 | 542,139 | Feb 12, 2020, 04:20 PM |
| Kauffman Michael | Chief Executive Officer | Feb 10, 2020 | Sale | $16.93 | 10,000 | 169,327 | 743,506 | Feb 12, 2020, 04:20 PM |
| Mirza Mansoor Raza | Director | Jan 09, 2020 | Option Exercise | $8.06 | 2,056 | 16,571 | 2,056 | Jan 13, 2020, 05:02 PM |
| Mirza Mansoor Raza | Director | Jan 09, 2020 | Sale | $20.00 | 2,056 | 41,120 | 0 | Jan 13, 2020, 05:02 PM |
| Kauffman Michael | Chief Executive Officer | Jan 08, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 753,506 | Jan 10, 2020, 05:07 PM |
| Kauffman Michael | Chief Executive Officer | Jan 09, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 552,139 | Jan 10, 2020, 05:07 PM |
| Kauffman Michael | Chief Executive Officer | Jan 09, 2020 | Sale | $19.19 | 10,000 | 191,880 | 542,139 | Jan 10, 2020, 05:07 PM |
| Kauffman Michael | Chief Executive Officer | Jan 08, 2020 | Sale | $18.57 | 10,000 | 185,705 | 743,506 | Jan 10, 2020, 05:07 PM |
| Shacham Sharon | President & CSO | Jan 08, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 753,506 | Jan 10, 2020, 05:04 PM |
| Shacham Sharon | President & CSO | Jan 09, 2020 | Option Exercise | $4.75 | 10,000 | 47,520 | 552,139 | Jan 10, 2020, 05:04 PM |
| Shacham Sharon | President & CSO | Jan 09, 2020 | Sale | $19.19 | 10,000 | 191,880 | 542,139 | Jan 10, 2020, 05:04 PM |
| Shacham Sharon | President & CSO | Jan 08, 2020 | Sale | $18.57 | 10,000 | 185,705 | 743,506 | Jan 10, 2020, 05:04 PM |
| Mirza Mansoor Raza | Director | Dec 27, 2019 | Option Exercise | $8.06 | 2,944 | 23,729 | 2,944 | Dec 31, 2019, 09:15 AM |
| Mirza Mansoor Raza | Director | Dec 27, 2019 | Sale | $20.00 | 2,944 | 58,880 | 0 | Dec 31, 2019, 09:15 AM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Dec 27, 2019 | Option Exercise | $10.39 | 5,000 | 51,950 | 8,653 | Dec 31, 2019, 09:06 AM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Dec 27, 2019 | Sale | $20.00 | 5,000 | 100,000 | 3,653 | Dec 31, 2019, 09:06 AM |
| Mirza Mansoor Raza | Director | Dec 18, 2019 | Option Exercise | $1.49 | 12,121 | 18,000 | 12,121 | Dec 20, 2019, 04:04 PM |
| Mirza Mansoor Raza | Director | Dec 18, 2019 | Sale | $17.18 | 12,121 | 208,236 | 7,121 | Dec 20, 2019, 04:04 PM |
| Mirza Mansoor Raza | Director | Dec 09, 2019 | Option Exercise | $5.64 | 10,342 | 58,360 | 10,342 | Dec 11, 2019, 05:26 PM |
| Mirza Mansoor Raza | Director | Dec 09, 2019 | Sale | $17.02 | 10,342 | 176,034 | 5,342 | Dec 11, 2019, 05:26 PM |
| Kauffman Michael | Chief Executive Officer | Dec 09, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 741,134 | Dec 11, 2019, 05:24 PM |
| Kauffman Michael | Chief Executive Officer | Dec 10, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 539,767 | Dec 11, 2019, 05:24 PM |
| Kauffman Michael | Chief Executive Officer | Dec 09, 2019 | Sale | $17.02 | 10,000 | 170,210 | 731,134 | Dec 11, 2019, 05:24 PM |
| Kauffman Michael | Chief Executive Officer | Dec 10, 2019 | Sale | $15.99 | 10,000 | 159,896 | 529,767 | Dec 11, 2019, 05:24 PM |
| Shacham Sharon | President & CSO | Dec 10, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 539,767 | Dec 11, 2019, 05:21 PM |
| Shacham Sharon | President & CSO | Dec 09, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 741,134 | Dec 11, 2019, 05:21 PM |
| Shacham Sharon | President & CSO | Dec 10, 2019 | Sale | $15.99 | 10,000 | 159,896 | 529,767 | Dec 11, 2019, 05:21 PM |
| Shacham Sharon | President & CSO | Dec 09, 2019 | Sale | $17.02 | 10,000 | 170,210 | 731,134 | Dec 11, 2019, 05:21 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Dec 06, 2019 | Option Exercise | $8.47 | 10,000 | 84,650 | 16,653 | Dec 10, 2019, 05:18 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Dec 06, 2019 | Sale | $17.45 | 13,000 | 226,908 | 11,653 | Dec 10, 2019, 05:18 PM |
| Kauffman Michael | Chief Executive Officer | Nov 08, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 741,134 | Nov 12, 2019, 04:39 PM |
| Kauffman Michael | Chief Executive Officer | Nov 11, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 539,767 | Nov 12, 2019, 04:39 PM |
| Kauffman Michael | Chief Executive Officer | Nov 11, 2019 | Sale | $14.76 | 10,000 | 147,610 | 529,767 | Nov 12, 2019, 04:39 PM |
| Kauffman Michael | Chief Executive Officer | Nov 08, 2019 | Sale | $14.63 | 10,000 | 146,254 | 731,134 | Nov 12, 2019, 04:39 PM |
| Shacham Sharon | President & CSO | Nov 08, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 741,134 | Nov 12, 2019, 04:34 PM |
| Shacham Sharon | President & CSO | Nov 11, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 539,767 | Nov 12, 2019, 04:34 PM |
| Shacham Sharon | President & CSO | Nov 11, 2019 | Sale | $14.76 | 10,000 | 147,610 | 529,767 | Nov 12, 2019, 04:34 PM |
| Shacham Sharon | President & CSO | Nov 08, 2019 | Sale | $14.63 | 10,000 | 146,254 | 731,134 | Nov 12, 2019, 04:34 PM |
| Shacham Sharon | President & CSO | Nov 01, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 539,767 | Nov 05, 2019, 04:10 PM |
| Shacham Sharon | President & CSO | Nov 01, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 741,134 | Nov 05, 2019, 04:10 PM |
| Shacham Sharon | President & CSO | Nov 01, 2019 | Sale | $12.00 | 10,000 | 120,000 | 529,767 | Nov 05, 2019, 04:10 PM |
| Shacham Sharon | President & CSO | Nov 01, 2019 | Sale | $12.00 | 10,000 | 120,000 | 731,134 | Nov 05, 2019, 04:10 PM |
| Kauffman Michael | Chief Executive Officer | Nov 01, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 741,134 | Nov 05, 2019, 04:08 PM |
| Kauffman Michael | Chief Executive Officer | Nov 01, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 539,767 | Nov 05, 2019, 04:08 PM |
| Kauffman Michael | Chief Executive Officer | Nov 01, 2019 | Sale | $12.00 | 10,000 | 120,000 | 529,767 | Nov 05, 2019, 04:08 PM |
| Kauffman Michael | Chief Executive Officer | Nov 01, 2019 | Sale | $12.00 | 10,000 | 120,000 | 731,134 | Nov 05, 2019, 04:08 PM |
| Kauffman Michael | Chief Executive Officer | Sep 16, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 741,134 | Sep 17, 2019, 04:56 PM |
| Kauffman Michael | Chief Executive Officer | Sep 16, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 539,767 | Sep 17, 2019, 04:56 PM |
| Kauffman Michael | Chief Executive Officer | Sep 16, 2019 | Sale | $12.00 | 10,000 | 120,000 | 731,134 | Sep 17, 2019, 04:56 PM |
| Kauffman Michael | Chief Executive Officer | Sep 16, 2019 | Sale | $12.00 | 10,000 | 120,000 | 529,767 | Sep 17, 2019, 04:56 PM |
| Shacham Sharon | President & CSO | Sep 16, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 539,767 | Sep 17, 2019, 04:54 PM |
| Shacham Sharon | President & CSO | Sep 16, 2019 | Option Exercise | $4.75 | 10,000 | 47,520 | 741,134 | Sep 17, 2019, 04:54 PM |
| Shacham Sharon | President & CSO | Sep 16, 2019 | Sale | $12.00 | 10,000 | 120,000 | 529,767 | Sep 17, 2019, 04:54 PM |
| Shacham Sharon | President & CSO | Sep 16, 2019 | Sale | $12.00 | 10,000 | 120,000 | 731,134 | Sep 17, 2019, 04:54 PM |
| Chione Ltd | 10% Owner | Feb 28, 2019 | Sale | $4.14 | 149,624 | 619,114 | 6,000,000 | Mar 04, 2019, 08:28 PM |
| Chione Ltd | 10% Owner | Feb 26, 2019 | Sale | $5.00 | 123,400 | 617,210 | 6,707,867 | Feb 27, 2019, 08:12 PM |
| Chione Ltd | 10% Owner | Feb 25, 2019 | Sale | $4.99 | 800,000 | 3,994,880 | 6,831,267 | Feb 27, 2019, 08:12 PM |
| Chione Ltd | 10% Owner | Feb 27, 2019 | Sale | $4.51 | 558,243 | 2,515,834 | 6,149,624 | Feb 27, 2019, 08:12 PM |
| Kauffman Michael | Chief Executive Officer | Jan 07, 2019 | Option Exercise | $0.03 | 12,500 | 412 | 743,634 | Jan 09, 2019, 04:41 PM |
| Kauffman Michael | Chief Executive Officer | Jan 07, 2019 | Sale | $10.23 | 12,500 | 127,824 | 731,134 | Jan 09, 2019, 04:41 PM |
| Shacham Sharon | President & CSO | Jan 07, 2019 | Option Exercise | $0.03 | 12,500 | 412 | 743,634 | Jan 09, 2019, 04:37 PM |
| Shacham Sharon | President & CSO | Jan 07, 2019 | Sale | $10.23 | 12,500 | 127,824 | 731,134 | Jan 09, 2019, 04:37 PM |
| Kauffman Michael | Chief Executive Officer | Dec 07, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Dec 10, 2018, 04:29 PM |
| Kauffman Michael | Chief Executive Officer | Dec 07, 2018 | Sale | $10.11 | 12,500 | 126,423 | 713,510 | Dec 10, 2018, 04:29 PM |
| Shacham Sharon | President & CSO | Dec 07, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Dec 10, 2018, 04:28 PM |
| Shacham Sharon | President & CSO | Dec 07, 2018 | Sale | $10.11 | 12,500 | 126,423 | 713,510 | Dec 10, 2018, 04:28 PM |
| Shacham Sharon | President & CSO | Nov 26, 2018 | Option Exercise | $4.75 | 9,600 | 45,619 | 521,743 | Nov 27, 2018, 04:20 PM |
| Shacham Sharon | President & CSO | Nov 26, 2018 | Sale | $11.00 | 9,600 | 105,600 | 512,143 | Nov 27, 2018, 04:20 PM |
| Kauffman Michael | Chief Executive Officer | Nov 26, 2018 | Option Exercise | $4.75 | 9,600 | 45,619 | 521,743 | Nov 27, 2018, 04:17 PM |
| Kauffman Michael | Chief Executive Officer | Nov 26, 2018 | Sale | $11.00 | 9,600 | 105,600 | 512,143 | Nov 27, 2018, 04:17 PM |
| Shacham Sharon | President & CSO | Nov 19, 2018 | Option Exercise | $4.75 | 400 | 1,901 | 512,543 | Nov 21, 2018, 08:03 AM |
| Shacham Sharon | President & CSO | Nov 19, 2018 | Sale | $11.14 | 400 | 4,455 | 512,143 | Nov 21, 2018, 08:03 AM |
| Kauffman Michael | Chief Executive Officer | Nov 19, 2018 | Option Exercise | $4.75 | 400 | 1,901 | 512,543 | Nov 21, 2018, 08:00 AM |
| Kauffman Michael | Chief Executive Officer | Nov 19, 2018 | Sale | $11.14 | 400 | 4,455 | 512,143 | Nov 21, 2018, 08:00 AM |
| Kauffman Michael | Chief Executive Officer | Nov 07, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Nov 09, 2018, 04:17 PM |
| Kauffman Michael | Chief Executive Officer | Nov 07, 2018 | Sale | $11.65 | 12,500 | 145,592 | 713,510 | Nov 09, 2018, 04:17 PM |
| Shacham Sharon | President & CSO | Nov 07, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Nov 09, 2018, 04:16 PM |
| Shacham Sharon | President & CSO | Nov 07, 2018 | Sale | $11.65 | 12,500 | 145,592 | 713,510 | Nov 09, 2018, 04:16 PM |
| Shacham Sharon | President & CSO | Oct 18, 2018 | Option Exercise | $4.75 | 10,000 | 47,520 | 522,143 | Oct 22, 2018, 04:09 PM |
| Shacham Sharon | President & CSO | Oct 18, 2018 | Sale | $12.63 | 10,000 | 126,304 | 512,143 | Oct 22, 2018, 04:09 PM |
| Kauffman Michael | Chief Executive Officer | Oct 18, 2018 | Option Exercise | $4.75 | 10,000 | 47,520 | 522,143 | Oct 22, 2018, 04:06 PM |
| Kauffman Michael | Chief Executive Officer | Oct 18, 2018 | Sale | $12.63 | 10,000 | 126,304 | 512,143 | Oct 22, 2018, 04:06 PM |
| Kauffman Michael | Chief Executive Officer | Oct 08, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Oct 09, 2018, 08:05 AM |
| Kauffman Michael | Chief Executive Officer | Oct 08, 2018 | Sale | $15.75 | 12,500 | 196,832 | 719,510 | Oct 09, 2018, 08:05 AM |
| Shacham Sharon | President & CSO | Oct 08, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Oct 09, 2018, 08:00 AM |
| Shacham Sharon | President & CSO | Oct 08, 2018 | Sale | $15.75 | 12,500 | 196,832 | 719,510 | Oct 09, 2018, 08:00 AM |
| Shacham Sharon | President & CSO | Sep 18, 2018 | Option Exercise | $4.75 | 10,000 | 47,520 | 522,143 | Sep 18, 2018, 05:26 PM |
| Shacham Sharon | President & CSO | Sep 18, 2018 | Sale | $18.26 | 10,000 | 182,615 | 512,143 | Sep 18, 2018, 05:26 PM |
| Kauffman Michael | Chief Executive Officer | Sep 18, 2018 | Option Exercise | $4.75 | 10,000 | 47,520 | 522,143 | Sep 18, 2018, 05:23 PM |
| Kauffman Michael | Chief Executive Officer | Sep 18, 2018 | Sale | $18.26 | 10,000 | 182,615 | 512,143 | Sep 18, 2018, 05:23 PM |
| Kauffman Michael | Chief Executive Officer | Sep 07, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Sep 10, 2018, 04:13 PM |
| Kauffman Michael | Chief Executive Officer | Sep 07, 2018 | Sale | $19.31 | 12,500 | 241,384 | 713,510 | Sep 10, 2018, 04:13 PM |
| Shacham Sharon | President & CSO | Sep 07, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Sep 10, 2018, 04:11 PM |
| Shacham Sharon | President & CSO | Sep 07, 2018 | Sale | $19.31 | 12,500 | 241,384 | 713,510 | Sep 10, 2018, 04:11 PM |
| Chione Ltd | 10% Owner | Sep 05, 2018 | Sale | $21.06 | 160,000 | 3,370,256 | 7,636,067 | Sep 07, 2018, 06:27 PM |
| Chione Ltd | 10% Owner | Sep 06, 2018 | Sale | $20.52 | 4,800 | 98,474 | 7,631,267 | Sep 07, 2018, 06:27 PM |
| Chione Ltd | 10% Owner | Sep 04, 2018 | Sale | $20.60 | 40,000 | 824,072 | 7,796,067 | Sep 04, 2018, 06:59 PM |
| Chione Ltd | 10% Owner | Aug 31, 2018 | Sale | $21.05 | 11,468 | 241,396 | 7,836,067 | Sep 04, 2018, 06:59 PM |
| Chione Ltd | 10% Owner | Aug 30, 2018 | Sale | $21.00 | 200,000 | 4,199,900 | 7,847,535 | Sep 04, 2018, 06:59 PM |
| Mirza Mansoor Raza | Director | Aug 30, 2018 | Option Exercise | $1.92 | 2,500 | 4,810 | 2,236 | Sep 04, 2018, 04:10 PM |
| Mirza Mansoor Raza | Director | Aug 30, 2018 | Sale | $21.00 | 2,500 | 52,500 | 0 | Sep 04, 2018, 04:10 PM |
| Mirza Mansoor Raza | Director | Aug 29, 2018 | Option Exercise | $1.49 | 2,500 | 3,713 | 2,500 | Aug 30, 2018, 04:38 PM |
| Mirza Mansoor Raza | Director | Aug 29, 2018 | Sale | $20.00 | 2,500 | 50,000 | 0 | Aug 30, 2018, 04:38 PM |
| Chione Ltd | 10% Owner | Aug 29, 2018 | Sale | $19.59 | 200,000 | 3,918,280 | 8,047,535 | Aug 29, 2018, 08:12 PM |
| Chione Ltd | 10% Owner | Aug 27, 2018 | Sale | $18.52 | 14,026 | 259,776 | 8,247,535 | Aug 29, 2018, 08:12 PM |
| Shacham Sharon | President & CSO | Aug 20, 2018 | Option Exercise | $4.75 | 10,000 | 47,520 | 522,143 | Aug 21, 2018, 04:14 PM |
| Shacham Sharon | President & CSO | Aug 20, 2018 | Sale | $17.46 | 10,000 | 174,568 | 512,143 | Aug 21, 2018, 04:14 PM |
| Kauffman Michael | Chief Executive Officer | Aug 20, 2018 | Option Exercise | $4.75 | 10,000 | 47,520 | 522,143 | Aug 21, 2018, 04:11 PM |
| Kauffman Michael | Chief Executive Officer | Aug 20, 2018 | Sale | $17.46 | 10,000 | 174,568 | 512,143 | Aug 21, 2018, 04:11 PM |
| Chione Ltd | 10% Owner | Aug 10, 2018 | Sale | $18.50 | 702 | 12,987 | 8,261,561 | Aug 14, 2018, 07:08 PM |
| Chione Ltd | 10% Owner | Aug 09, 2018 | Sale | $18.51 | 67,474 | 1,248,782 | 8,262,263 | Aug 09, 2018, 08:24 PM |
| Chione Ltd | 10% Owner | Aug 08, 2018 | Sale | $18.61 | 2,800 | 52,098 | 8,329,737 | Aug 09, 2018, 08:24 PM |
| Chione Ltd | 10% Owner | Aug 07, 2018 | Sale | $18.60 | 10,602 | 197,197 | 8,332,537 | Aug 09, 2018, 08:24 PM |
| Kauffman Michael | Chief Executive Officer | Aug 07, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Aug 08, 2018, 04:08 PM |
| Kauffman Michael | Chief Executive Officer | Aug 07, 2018 | Sale | $18.04 | 12,500 | 225,556 | 713,510 | Aug 08, 2018, 04:08 PM |
| Shacham Sharon | President & CSO | Aug 07, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Aug 08, 2018, 04:04 PM |
| Shacham Sharon | President & CSO | Aug 07, 2018 | Sale | $18.04 | 12,500 | 225,556 | 713,510 | Aug 08, 2018, 04:04 PM |
| Chione Ltd | 10% Owner | Jul 25, 2018 | Sale | $18.52 | 895 | 16,571 | 8,343,139 | Jul 25, 2018, 07:55 PM |
| Chione Ltd | 10% Owner | Jul 24, 2018 | Sale | $18.63 | 9,144 | 170,342 | 8,344,034 | Jul 25, 2018, 07:55 PM |
| Chione Ltd | 10% Owner | Jul 23, 2018 | Sale | $18.66 | 20,000 | 373,222 | 8,353,178 | Jul 25, 2018, 07:55 PM |
| Chione Ltd | 10% Owner | Jul 19, 2018 | Sale | $18.90 | 100,000 | 1,889,940 | 8,399,920 | Jul 23, 2018, 05:00 PM |
| Chione Ltd | 10% Owner | Jul 20, 2018 | Sale | $19.21 | 26,742 | 513,805 | 8,373,178 | Jul 23, 2018, 05:00 PM |
| Shacham Sharon | President & CSO | Jul 18, 2018 | Option Exercise | $2.17 | 10,000 | 21,678 | 522,143 | Jul 20, 2018, 04:28 PM |
| Shacham Sharon | President & CSO | Jul 18, 2018 | Sale | $18.27 | 10,000 | 182,686 | 512,143 | Jul 20, 2018, 04:28 PM |
| Kauffman Michael | Chief Executive Officer | Jul 18, 2018 | Option Exercise | $2.17 | 10,000 | 21,678 | 522,143 | Jul 20, 2018, 04:23 PM |
| Kauffman Michael | Chief Executive Officer | Jul 18, 2018 | Sale | $18.27 | 10,000 | 182,686 | 512,143 | Jul 20, 2018, 04:23 PM |
| Chione Ltd | 10% Owner | Jul 16, 2018 | Sale | $18.52 | 2,654 | 49,161 | 8,547,266 | Jul 18, 2018, 07:34 PM |
| Chione Ltd | 10% Owner | Jul 18, 2018 | Sale | $18.53 | 30,000 | 556,005 | 8,499,920 | Jul 18, 2018, 07:34 PM |
| Chione Ltd | 10% Owner | Jul 17, 2018 | Sale | $18.50 | 17,346 | 320,901 | 8,529,920 | Jul 18, 2018, 07:34 PM |
| Kauffman Michael | Chief Executive Officer | Jul 09, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Jul 10, 2018, 04:10 PM |
| Kauffman Michael | Chief Executive Officer | Jul 09, 2018 | Sale | $18.72 | 12,500 | 233,990 | 713,510 | Jul 10, 2018, 04:10 PM |
| Shacham Sharon | President & CSO | Jul 09, 2018 | Option Exercise | $0.03 | 12,500 | 412 | 726,010 | Jul 10, 2018, 04:09 PM |
| Shacham Sharon | President & CSO | Jul 09, 2018 | Sale | $18.72 | 12,500 | 233,990 | 713,510 | Jul 10, 2018, 04:09 PM |
| Shacham Sharon | President & CSO | Jun 18, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Jun 19, 2018, 04:06 PM |
| Shacham Sharon | President & CSO | Jun 18, 2018 | Sale | $18.66 | 10,000 | 186,558 | 512,143 | Jun 19, 2018, 04:06 PM |
| Kauffman Michael | Chief Executive Officer | Jun 18, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Jun 19, 2018, 04:05 PM |
| Kauffman Michael | Chief Executive Officer | Jun 18, 2018 | Sale | $18.66 | 10,000 | 186,558 | 512,143 | Jun 19, 2018, 04:05 PM |
| Kauffman Michael | Chief Executive Officer | Jun 07, 2018 | Option Exercise | $0.26 | 10,000 | 2,570 | 723,510 | Jun 11, 2018, 04:17 PM |
| Kauffman Michael | Chief Executive Officer | Jun 07, 2018 | Sale | $17.30 | 10,000 | 172,991 | 713,510 | Jun 11, 2018, 04:17 PM |
| Shacham Sharon | President & CSO | Jun 07, 2018 | Option Exercise | $0.26 | 10,000 | 2,570 | 723,510 | Jun 11, 2018, 04:11 PM |
| Shacham Sharon | President & CSO | Jun 07, 2018 | Sale | $17.30 | 10,000 | 172,991 | 713,510 | Jun 11, 2018, 04:11 PM |
| Shacham Sharon | President & CSO | May 18, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | May 21, 2018, 04:28 PM |
| Shacham Sharon | President & CSO | May 18, 2018 | Sale | $19.39 | 10,000 | 193,870 | 512,143 | May 21, 2018, 04:28 PM |
| Kauffman Michael | Chief Executive Officer | May 18, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | May 21, 2018, 04:26 PM |
| Kauffman Michael | Chief Executive Officer | May 18, 2018 | Sale | $19.39 | 10,000 | 193,870 | 512,143 | May 21, 2018, 04:26 PM |
| Mirza Mansoor Raza | Director | May 10, 2018 | Option Exercise | $1.07 | 2,000 | 2,146 | 1,325 | May 11, 2018, 04:08 PM |
| Mirza Mansoor Raza | Director | May 10, 2018 | Sale | $18.00 | 2,000 | 36,000 | 0 | May 11, 2018, 04:08 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | May 10, 2018 | Sale | $18.01 | 2,000 | 36,024 | 2,881 | May 10, 2018, 04:10 PM |
| Kauffman Michael | Chief Executive Officer | May 07, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | May 08, 2018, 04:21 PM |
| Kauffman Michael | Chief Executive Officer | May 07, 2018 | Sale | $16.77 | 10,000 | 167,747 | 713,510 | May 08, 2018, 04:21 PM |
| Shacham Sharon | President & CSO | May 07, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | May 08, 2018, 04:19 PM |
| Shacham Sharon | President & CSO | May 07, 2018 | Sale | $16.77 | 10,000 | 167,747 | 713,510 | May 08, 2018, 04:19 PM |
| Shacham Sharon | President & CSO | Apr 18, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Apr 20, 2018, 04:07 PM |
| Shacham Sharon | President & CSO | Apr 18, 2018 | Sale | $14.79 | 10,000 | 147,878 | 512,143 | Apr 20, 2018, 04:07 PM |
| Kauffman Michael | Chief Executive Officer | Apr 18, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Apr 20, 2018, 04:06 PM |
| Kauffman Michael | Chief Executive Officer | Apr 18, 2018 | Sale | $14.79 | 10,000 | 147,878 | 512,143 | Apr 20, 2018, 04:06 PM |
| Kauffman Michael | Chief Executive Officer | Apr 09, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | Apr 10, 2018, 04:20 PM |
| Kauffman Michael | Chief Executive Officer | Apr 09, 2018 | Sale | $12.48 | 10,000 | 124,829 | 713,510 | Apr 10, 2018, 04:20 PM |
| Shacham Sharon | President & CSO | Apr 09, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | Apr 10, 2018, 04:17 PM |
| Shacham Sharon | President & CSO | Apr 09, 2018 | Sale | $12.48 | 10,000 | 124,829 | 713,510 | Apr 10, 2018, 04:17 PM |
| Shacham Sharon | President & CSO | Mar 19, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Mar 20, 2018, 04:36 PM |
| Shacham Sharon | President & CSO | Mar 19, 2018 | Sale | $15.29 | 10,000 | 152,895 | 512,143 | Mar 20, 2018, 04:36 PM |
| Kauffman Michael | Chief Executive Officer | Mar 19, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Mar 20, 2018, 04:34 PM |
| Kauffman Michael | Chief Executive Officer | Mar 19, 2018 | Sale | $15.29 | 10,000 | 152,895 | 512,143 | Mar 20, 2018, 04:34 PM |
| Mirza Mansoor Raza | Director | Mar 12, 2018 | Option Exercise | $0.26 | 2,500 | 660 | 2,500 | Mar 14, 2018, 05:08 PM |
| Mirza Mansoor Raza | Director | Mar 12, 2018 | Sale | $17.01 | 2,500 | 42,525 | 0 | Mar 14, 2018, 05:08 PM |
| Kauffman Michael | Chief Executive Officer | Mar 07, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | Mar 08, 2018, 05:57 PM |
| Kauffman Michael | Chief Executive Officer | Mar 07, 2018 | Sale | $16.15 | 10,000 | 161,463 | 713,510 | Mar 08, 2018, 05:57 PM |
| Shacham Sharon | President & CSO | Mar 07, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | Mar 08, 2018, 05:54 PM |
| Shacham Sharon | President & CSO | Mar 07, 2018 | Sale | $16.15 | 10,000 | 161,463 | 713,510 | Mar 08, 2018, 05:54 PM |
| Mirza Mansoor Raza | Director | Mar 05, 2018 | Option Exercise | $0.26 | 2,500 | 660 | 2,500 | Mar 06, 2018, 04:56 PM |
| Mirza Mansoor Raza | Director | Mar 05, 2018 | Sale | $16.00 | 2,500 | 40,000 | 0 | Mar 06, 2018, 04:56 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Mar 05, 2018 | Sale | $16.03 | 2,500 | 40,076 | 4,881 | Mar 06, 2018, 04:54 PM |
| Shacham Sharon | President & CSO | Feb 20, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Feb 22, 2018, 04:17 PM |
| Shacham Sharon | President & CSO | Feb 20, 2018 | Sale | $14.79 | 10,000 | 147,872 | 512,143 | Feb 22, 2018, 04:17 PM |
| Kauffman Michael | Chief Executive Officer | Feb 20, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Feb 22, 2018, 04:15 PM |
| Kauffman Michael | Chief Executive Officer | Feb 20, 2018 | Sale | $14.79 | 10,000 | 147,872 | 512,143 | Feb 22, 2018, 04:15 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Feb 16, 2018 | Sale | $15.01 | 1,486 | 22,298 | 7,381 | Feb 20, 2018, 04:21 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Feb 15, 2018 | Sale | $15.02 | 1,014 | 15,229 | 8,867 | Feb 20, 2018, 04:21 PM |
| Mirza Mansoor Raza | Director | Feb 08, 2018 | Option Exercise | $0.26 | 1,500 | 396 | 1,500 | Feb 12, 2018, 04:32 PM |
| Mirza Mansoor Raza | Director | Feb 08, 2018 | Sale | $14.00 | 1,500 | 21,000 | 0 | Feb 12, 2018, 04:32 PM |
| Mirza Mansoor Raza | Director | Feb 07, 2018 | Option Exercise | $0.26 | 1,500 | 396 | 1,500 | Feb 08, 2018, 04:11 PM |
| Mirza Mansoor Raza | Director | Feb 07, 2018 | Sale | $13.00 | 1,500 | 19,500 | 0 | Feb 08, 2018, 04:11 PM |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | Feb 07, 2018 | Sale | $13.00 | 1,500 | 19,500 | 9,881 | Feb 08, 2018, 04:10 PM |
| Kauffman Michael | Chief Executive Officer | Feb 07, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | Feb 08, 2018, 04:08 PM |
| Kauffman Michael | Chief Executive Officer | Feb 07, 2018 | Sale | $12.50 | 10,000 | 125,048 | 713,510 | Feb 08, 2018, 04:08 PM |
| Shacham Sharon | President & CSO | Feb 07, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | Feb 08, 2018, 04:07 PM |
| Shacham Sharon | President & CSO | Feb 07, 2018 | Sale | $12.50 | 10,000 | 125,048 | 713,510 | Feb 08, 2018, 04:07 PM |
| Shacham Sharon | President & CSO | Jan 18, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Jan 22, 2018, 04:08 PM |
| Shacham Sharon | President & CSO | Jan 18, 2018 | Sale | $10.09 | 10,000 | 100,882 | 512,143 | Jan 22, 2018, 04:08 PM |
| Kauffman Michael | Chief Executive Officer | Jan 18, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Jan 22, 2018, 04:05 PM |
| Kauffman Michael | Chief Executive Officer | Jan 18, 2018 | Sale | $10.09 | 10,000 | 100,882 | 512,143 | Jan 22, 2018, 04:05 PM |
| Kauffman Michael | Chief Executive Officer | Jan 08, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | Jan 09, 2018, 04:10 PM |
| Kauffman Michael | Chief Executive Officer | Jan 08, 2018 | Sale | $10.08 | 10,000 | 100,769 | 713,510 | Jan 09, 2018, 04:10 PM |
| Shacham Sharon | President & CSO | Jan 08, 2018 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | Jan 09, 2018, 04:08 PM |
| Shacham Sharon | President & CSO | Jan 08, 2018 | Sale | $10.08 | 10,000 | 100,769 | 713,510 | Jan 09, 2018, 04:08 PM |
| Shacham Sharon | President & CSO | Dec 18, 2017 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Dec 20, 2017, 04:21 PM |
| Shacham Sharon | President & CSO | Dec 18, 2017 | Sale | $9.16 | 10,000 | 91,553 | 512,143 | Dec 20, 2017, 04:21 PM |
| Kauffman Michael | Chief Executive Officer | Dec 18, 2017 | Option Exercise | $0.26 | 10,000 | 2,640 | 522,143 | Dec 20, 2017, 04:19 PM |
| Kauffman Michael | Chief Executive Officer | Dec 18, 2017 | Sale | $9.16 | 10,000 | 91,553 | 512,143 | Dec 20, 2017, 04:19 PM |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | Dec 12, 2017 | Option Exercise | $6.54 | 17,000 | 111,180 | 28,381 | Dec 13, 2017, 04:04 PM |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | Dec 12, 2017 | Sale | $9.92 | 17,000 | 168,616 | 12,025 | Dec 13, 2017, 04:04 PM |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | Dec 11, 2017 | Sale | $10.88 | 10,042 | 109,256 | 11,381 | Dec 13, 2017, 04:04 PM |
| Kauffman Michael | Chief Executive Officer | Dec 07, 2017 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | Dec 08, 2017, 04:07 PM |
| Kauffman Michael | Chief Executive Officer | Dec 07, 2017 | Sale | $10.39 | 10,000 | 103,903 | 713,510 | Dec 08, 2017, 04:07 PM |
| Shacham Sharon | President & CSO | Dec 07, 2017 | Option Exercise | $0.26 | 10,000 | 2,640 | 723,510 | Dec 08, 2017, 04:05 PM |
| Shacham Sharon | President & CSO | Dec 07, 2017 | Sale | $10.39 | 10,000 | 103,903 | 713,510 | Dec 08, 2017, 04:05 PM |
| Frenkel Ran | Chief Dev Operations Officer | Nov 07, 2017 | Sale | $11.25 | 4,958 | 55,755 | 24,733 | Nov 09, 2017, 04:04 PM |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | Nov 07, 2017 | Sale | $11.25 | 4,958 | 55,755 | 21,423 | Nov 09, 2017, 04:03 PM |
| Mirza Mansoor Raza | Director | Oct 02, 2017 | Option Exercise | $0.26 | 2,000 | 528 | 2,000 | Oct 04, 2017, 04:08 PM |
| Mirza Mansoor Raza | Director | Oct 02, 2017 | Sale | $12.00 | 2,000 | 24,000 | 0 | Oct 04, 2017, 04:08 PM |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | Oct 02, 2017 | Sale | $12.00 | 1,500 | 18,000 | 11,381 | Oct 04, 2017, 04:06 PM |
| Mirza Mansoor Raza | Director | Sep 15, 2017 | Option Exercise | $0.26 | 2,882 | 761 | 2,882 | Sep 18, 2017, 04:11 PM |
| Mirza Mansoor Raza | Director | Sep 15, 2017 | Sale | $11.00 | 2,882 | 31,702 | 0 | Sep 18, 2017, 04:11 PM |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | Sep 15, 2017 | Sale | $11.00 | 2,000 | 22,000 | 12,881 | Sep 18, 2017, 04:09 PM |
| Mirza Mansoor Raza | Director | Sep 11, 2017 | Option Exercise | $0.26 | 118 | 31 | 118 | Sep 13, 2017, 04:13 PM |
| Mirza Mansoor Raza | Director | Sep 11, 2017 | Sale | $11.00 | 118 | 1,298 | 0 | Sep 13, 2017, 04:13 PM |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | Jun 26, 2017 | Sale | $10.03 | 805 | 8,071 | 14,881 | Sep 01, 2017, 05:43 PM |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | Aug 29, 2017 | Sale | $10.00 | 2,195 | 21,950 | 15,686 | Aug 30, 2017, 04:09 PM |
| Frenkel Ran | Chief Dev Operations Officer | Nov 14, 2016 | Sale | $10.06 | 3,309 | 33,286 | 14,691 | Nov 15, 2016, 04:05 PM |
| Renz Justin A | EVP, CFO & Treasurer | Nov 09, 2016 | Sale | $8.19 | 4,342 | 35,544 | 19,173 | Nov 14, 2016, 05:49 PM |
| Primiano Christopher Brett | SVP,CORP DEV,GEN COUNSEL&SEC. | Nov 09, 2016 | Sale | $8.19 | 4,342 | 35,544 | 15,819 | Nov 14, 2016, 05:48 PM |
| Chione Ltd | 10% Owner | Jun 23, 2016 | Sale | $8.03 | 18,824 | 151,083 | 8,549,920 | Jun 27, 2016, 06:44 PM |
| Chione Ltd | 10% Owner | Jun 13, 2016 | Sale | $8.51 | 7,074 | 60,214 | 8,568,744 | Jun 15, 2016, 02:56 PM |
| Chione Ltd | 10% Owner | Jun 08, 2016 | Sale | $9.34 | 15,541 | 145,186 | 8,605,818 | Jun 10, 2016, 03:20 PM |
| Chione Ltd | 10% Owner | Jun 09, 2016 | Sale | $9.14 | 30,000 | 274,098 | 8,575,818 | Jun 10, 2016, 03:20 PM |
| Chione Ltd | 10% Owner | Jun 07, 2016 | Sale | $9.25 | 20,000 | 185,086 | 8,621,359 | Jun 08, 2016, 04:51 PM |
| Chione Ltd | 10% Owner | Jun 06, 2016 | Sale | $9.22 | 20,000 | 184,464 | 8,641,359 | Jun 08, 2016, 04:51 PM |
| Chione Ltd | 10% Owner | Jun 02, 2016 | Sale | $9.65 | 17,855 | 172,244 | 8,661,359 | Jun 06, 2016, 08:55 PM |
| Chione Ltd | 10% Owner | May 27, 2016 | Sale | $9.58 | 40,000 | 383,200 | 8,713,878 | Jun 01, 2016, 08:04 PM |
| Chione Ltd | 10% Owner | Jun 01, 2016 | Sale | $9.64 | 17,568 | 169,327 | 8,679,214 | Jun 01, 2016, 08:04 PM |
| Chione Ltd | 10% Owner | May 31, 2016 | Sale | $9.66 | 17,096 | 165,072 | 8,696,782 | Jun 01, 2016, 08:04 PM |
| Chione Ltd | 10% Owner | May 26, 2016 | Sale | $9.59 | 18,182 | 174,287 | 8,753,878 | May 27, 2016, 06:27 PM |
| Chione Ltd | 10% Owner | May 25, 2016 | Sale | $9.83 | 27,940 | 274,541 | 8,772,060 | May 27, 2016, 06:27 PM |
| Chione Ltd | 10% Owner | May 23, 2016 | Sale | $8.77 | 33,932 | 297,414 | 8,800,000 | May 23, 2016, 08:16 PM |
| Chione Ltd | 10% Owner | May 20, 2016 | Sale | $8.52 | 40,000 | 340,748 | 8,833,932 | May 23, 2016, 08:16 PM |
| Chione Ltd | 10% Owner | May 19, 2016 | Sale | $8.18 | 20,000 | 163,644 | 8,873,932 | May 23, 2016, 08:16 PM |
| Chione Ltd | 10% Owner | May 17, 2016 | Sale | $8.15 | 33,800 | 275,480 | 8,923,932 | May 19, 2016, 08:54 PM |
| Chione Ltd | 10% Owner | May 18, 2016 | Sale | $8.15 | 30,000 | 244,488 | 8,893,932 | May 19, 2016, 08:54 PM |
| Chione Ltd | 10% Owner | May 16, 2016 | Sale | $8.01 | 10,000 | 80,065 | 8,957,732 | May 17, 2016, 09:11 PM |
| Chione Ltd | 10% Owner | May 13, 2016 | Sale | $8.01 | 400 | 3,203 | 8,967,732 | May 17, 2016, 09:11 PM |
| Chione Ltd | 10% Owner | May 11, 2016 | Sale | $8.41 | 11,868 | 99,860 | 8,968,132 | May 12, 2016, 07:52 PM |
| Chione Ltd | 10% Owner | May 10, 2016 | Sale | $8.14 | 20,000 | 162,788 | 8,980,000 | May 12, 2016, 07:52 PM |
| Mirza Mansoor Raza | Director | Dec 08, 2015 | Option Exercise | $0.08 | 10,738 | 844 | 10,323 | Dec 10, 2015, 04:12 PM |
| Mirza Mansoor Raza | Director | Dec 08, 2015 | Sale | $15.01 | 15,000 | 225,136 | 4,262 | Dec 10, 2015, 04:12 PM |
| Frenkel Ran | EVP, WW Development Operations | Apr 07, 2015 | Buy | $33.00 | 2,000 | 66,000 | 3,000 | Apr 08, 2015, 04:12 PM |
| Frenkel Ran | EVP, WW Development Operations | Apr 06, 2015 | Buy | $29.43 | 1,000 | 29,430 | 1,000 | Apr 08, 2015, 04:12 PM |
| Greene Barry E | Director | Apr 02, 2015 | Buy | $29.31 | 3,000 | 87,938 | 3,000 | Apr 06, 2015, 05:57 PM |
| Renz Justin A | EVP, CFO & Treasurer | Apr 02, 2015 | Buy | $29.71 | 5,000 | 148,557 | 5,000 | Apr 06, 2015, 05:53 PM |
| WEG KENNETH E | Director | Apr 02, 2015 | Option Exercise | $29.55 | 5,000 | 147,760 | 5,000 | Apr 06, 2015, 05:35 PM |
| Shacham Sharon | President & CSO | Jan 12, 2015 | Sale | $33.00 | 25,000 | 825,000 | 562,596 | Jan 14, 2015, 04:07 PM |
| Shacham Sharon | President & CSO | Jan 12, 2015 | Sale | $33.00 | 25,000 | 825,000 | 763,963 | Jan 14, 2015, 04:07 PM |
| PAKIANATHAN DEEPIKA | Director | Jan 12, 2015 | Buy | $33.00 | 440 | 14,520 | 21,883 | Jan 14, 2015, 04:06 PM |
| PAKIANATHAN DEEPIKA | Director | Jan 12, 2015 | Buy | $33.00 | 45,014 | 1,485,462 | 2,241,123 | Jan 14, 2015, 04:06 PM |
| Kauffman Michael | Chief Executive Officer | Jan 12, 2015 | Sale | $33.00 | 25,000 | 825,000 | 562,596 | Jan 14, 2015, 04:03 PM |
| Kauffman Michael | Chief Executive Officer | Jan 12, 2015 | Sale | $33.00 | 25,000 | 825,000 | 763,963 | Jan 14, 2015, 04:03 PM |
| Mirza Mansoor Raza | Director | Dec 02, 2014 | Option Exercise | $0.03 | 5,000 | 165 | 9,262 | Dec 03, 2014, 04:15 PM |
| Mirza Mansoor Raza | Director | Dec 01, 2014 | Option Exercise | $0.03 | 1,535 | 51 | 9,262 | Dec 03, 2014, 04:15 PM |
| Mirza Mansoor Raza | Director | Dec 02, 2014 | Sale | $45.18 | 5,000 | 225,881 | 4,262 | Dec 03, 2014, 04:15 PM |
| Mirza Mansoor Raza | Director | Dec 01, 2014 | Sale | $41.86 | 5,000 | 209,286 | 4,262 | Dec 03, 2014, 04:15 PM |
| Chione Ltd | 10% Owner | Nov 26, 2014 | Sale | $42.38 | 55,000 | 2,330,917 | 9,355,815 | Dec 01, 2014, 08:58 PM |
| Chione Ltd | 10% Owner | Dec 01, 2014 | Sale | $41.76 | 198,115 | 8,273,223 | 9,132,700 | Dec 01, 2014, 08:58 PM |
| Chione Ltd | 10% Owner | Nov 28, 2014 | Sale | $42.18 | 25,000 | 1,054,520 | 9,330,815 | Dec 01, 2014, 08:58 PM |
| Chione Ltd | 10% Owner | Nov 25, 2014 | Sale | $43.14 | 125,000 | 5,393,104 | 9,482,642 | Nov 25, 2014, 09:13 PM |
| Chione Ltd | 10% Owner | Nov 24, 2014 | Sale | $41.78 | 75,000 | 3,133,800 | 9,535,815 | Nov 25, 2014, 09:13 PM |
| Chione Ltd | 10% Owner | Nov 21, 2014 | Sale | $41.29 | 42,800 | 1,767,143 | 9,610,815 | Nov 25, 2014, 09:13 PM |
| Chione Ltd | 10% Owner | Nov 19, 2014 | Sale | $40.01 | 60,268 | 2,411,021 | 9,653,615 | Nov 20, 2014, 07:06 PM |
| Chione Ltd | 10% Owner | Nov 18, 2014 | Sale | $41.01 | 5,700 | 233,770 | 9,713,883 | Nov 20, 2014, 07:06 PM |
| Chione Ltd | 10% Owner | Nov 11, 2014 | Sale | $42.51 | 54,100 | 2,299,878 | 9,631,883 | Nov 12, 2014, 08:10 PM |
| Chione Ltd | 10% Owner | Nov 10, 2014 | Sale | $43.40 | 65,000 | 2,820,802 | 9,719,583 | Nov 12, 2014, 08:10 PM |
| Chione Ltd | 10% Owner | Nov 12, 2014 | Sale | $42.39 | 45,000 | 1,907,348 | 9,593,083 | Nov 12, 2014, 08:10 PM |
| Mirza Mansoor Raza | Director | Nov 10, 2014 | Sale | $45.05 | 5,000 | 225,256 | 7,727 | Nov 12, 2014, 06:46 PM |
| Chione Ltd | 10% Owner | Nov 06, 2014 | Sale | $42.48 | 175,984 | 7,475,815 | 9,819,033 | Nov 06, 2014, 09:21 PM |
| Chione Ltd | 10% Owner | Nov 04, 2014 | Sale | $41.45 | 96,800 | 4,012,349 | 9,932,667 | Nov 06, 2014, 09:21 PM |
| Mirza Mansoor Raza | Director | Nov 03, 2014 | Sale | $40.95 | 5,000 | 204,750 | 12,727 | Nov 05, 2014, 05:04 PM |
| Mirza Mansoor Raza | Director | Oct 29, 2014 | Sale | $40.05 | 3,500 | 140,161 | 17,727 | Oct 31, 2014, 06:59 PM |
| Mirza Mansoor Raza | Director | Oct 20, 2014 | Sale | $35.04 | 1,500 | 52,560 | 21,227 | Oct 22, 2014, 07:53 PM |
| Chione Ltd | 10% Owner | Sep 26, 2014 | Sale | $42.65 | 200,000 | 8,529,202 | 10,074,318 | Sep 30, 2014, 09:56 PM |
| Czernik Marcin | 10% Owner | Sep 26, 2014 | Sale | $42.54 | 50,000 | 2,127,200 | 2,888,037 | Sep 30, 2014, 09:43 PM |
| Czernik Marcin | 10% Owner | Sep 24, 2014 | Sale | $40.32 | 22,498 | 907,133 | 2,900,517 | Sep 26, 2014, 07:11 PM |
| Czernik Marcin | 10% Owner | Sep 18, 2014 | Sale | $40.16 | 2,778 | 111,556 | 2,923,015 | Sep 19, 2014, 07:52 PM |
| Czernik Marcin | 10% Owner | Sep 17, 2014 | Sale | $40.26 | 9,569 | 385,270 | 2,925,793 | Sep 19, 2014, 07:52 PM |
| Chione Ltd | 10% Owner | Sep 12, 2014 | Sale | $41.12 | 4,312 | 177,325 | 10,223,767 | Sep 16, 2014, 07:47 PM |
| Czernik Marcin | 10% Owner | Sep 08, 2014 | Sale | $39.92 | 35,666 | 1,423,623 | 2,935,692 | Sep 10, 2014, 09:27 PM |
| Czernik Marcin | 10% Owner | Sep 04, 2014 | Sale | $38.07 | 12,795 | 487,095 | 2,971,358 | Sep 08, 2014, 09:13 PM |
| Czernik Marcin | 10% Owner | Aug 26, 2014 | Sale | $38.55 | 22,239 | 857,304 | 3,007,459 | Aug 28, 2014, 09:36 PM |
| Czernik Marcin | 10% Owner | Aug 27, 2014 | Sale | $39.07 | 21,460 | 838,431 | 2,984,153 | Aug 28, 2014, 09:36 PM |
| Czernik Marcin | 10% Owner | Aug 25, 2014 | Sale | $38.08 | 4,389 | 167,151 | 3,027,852 | Aug 27, 2014, 08:25 PM |
| Czernik Marcin | 10% Owner | Aug 18, 2014 | Sale | $39.10 | 3,175 | 124,132 | 3,032,241 | Aug 21, 2014, 09:44 PM |
| Czernik Marcin | 10% Owner | Aug 15, 2014 | Sale | $39.14 | 7,827 | 306,359 | 3,035,416 | Aug 18, 2014, 09:17 PM |
| Czernik Marcin | 10% Owner | Aug 14, 2014 | Sale | $38.04 | 200 | 7,609 | 3,043,243 | Aug 18, 2014, 09:17 PM |
| Czernik Marcin | 10% Owner | Aug 11, 2014 | Sale | $37.30 | 36,979 | 1,379,350 | 3,043,443 | Aug 13, 2014, 09:12 PM |
| Czernik Marcin | 10% Owner | Jul 30, 2014 | Sale | $37.13 | 41,481 | 1,540,115 | 3,080,422 | Aug 07, 2014, 09:23 PM |
| Czernik Marcin | 10% Owner | Jul 30, 2014 | Sale | $36.20 | 21,570 | 780,931 | 3,121,903 | Aug 01, 2014, 09:30 PM |
| Chione Ltd | 10% Owner | Jul 29, 2014 | Sale | $35.20 | 30,000 | 1,055,853 | 10,228,079 | Jul 31, 2014, 09:33 PM |
| Plio Ltd | 10% Owner | Jul 23, 2014 | Sale | $35.54 | 50,000 | 1,777,185 | 3,143,473 | Jul 28, 2014, 08:18 AM |
| Plio Ltd | 10% Owner | Jul 23, 2014 | Sale | $35.54 | 500,000 | 17,771,851 | 2,693,473 | Jul 25, 2014, 07:48 PM |
| Shacham Sharon | President & CSO | Jul 02, 2014 | Sale | $42.50 | 100,000 | 4,250,000 | 587,596 | Jul 02, 2014, 06:12 PM |
| Shacham Sharon | President & CSO | Jul 02, 2014 | Sale | $42.50 | 100,000 | 4,250,000 | 808,963 | Jul 02, 2014, 06:12 PM |
| Kauffman Michael | Chief Executive Officer | Jul 02, 2014 | Sale | $42.50 | 100,000 | 4,250,000 | 808,963 | Jul 02, 2014, 06:11 PM |
| Kauffman Michael | Chief Executive Officer | Jul 02, 2014 | Sale | $42.50 | 100,000 | 4,250,000 | 587,596 | Jul 02, 2014, 06:11 PM |
| Shacham Sharon | President & CSO | Jun 18, 2014 | Sale | $43.15 | 10,000 | 431,523 | 687,596 | Jun 19, 2014, 06:53 PM |
| Shacham Sharon | President & CSO | Jun 17, 2014 | Sale | $40.36 | 10,000 | 403,635 | 908,963 | Jun 19, 2014, 06:53 PM |
| Kauffman Michael | Chief Executive Officer | Jun 18, 2014 | Sale | $43.15 | 10,000 | 431,523 | 687,596 | Jun 19, 2014, 06:52 PM |
| Kauffman Michael | Chief Executive Officer | Jun 17, 2014 | Sale | $40.36 | 10,000 | 403,635 | 908,963 | Jun 19, 2014, 06:52 PM |
| PAKIANATHAN DEEPIKA | Director | May 22, 2014 | Buy | $26.09 | 19,807 | 516,769 | 2,194,357 | May 23, 2014, 07:44 PM |
| PAKIANATHAN DEEPIKA | Director | May 21, 2014 | Buy | $26.19 | 896 | 23,470 | 21,233 | May 23, 2014, 07:44 PM |
| PAKIANATHAN DEEPIKA | Director | May 21, 2014 | Buy | $26.19 | 91,754 | 2,403,404 | 2,174,550 | May 23, 2014, 07:44 PM |
| PAKIANATHAN DEEPIKA | Director | May 23, 2014 | Buy | $26.45 | 17 | 450 | 21,443 | May 23, 2014, 07:44 PM |
| PAKIANATHAN DEEPIKA | Director | May 23, 2014 | Buy | $26.45 | 1,752 | 46,334 | 2,196,109 | May 23, 2014, 07:44 PM |
| PAKIANATHAN DEEPIKA | Director | May 22, 2014 | Buy | $26.09 | 193 | 5,035 | 21,426 | May 23, 2014, 07:44 PM |
| Brannelly Paul | SVP, FINANCE & ADMIN, TREAS | May 15, 2014 | Buy | $25.95 | 700 | 18,165 | 66,136 | May 15, 2014, 04:42 PM |
| Brannelly Paul | SVP, FINANCE & ADMIN, TREAS | May 14, 2014 | Buy | $26.93 | 800 | 21,544 | 65,436 | May 14, 2014, 04:02 PM |
| Primiano Christopher Brett | VP, GEN COUNSEL & SECRETARY | May 13, 2014 | Buy | $26.75 | 1,000 | 26,750 | 1,000 | May 13, 2014, 05:22 PM |
| Brannelly Paul | SVP, FINANCE & ADMIN, TREAS | May 13, 2014 | Buy | $28.06 | 1,000 | 28,057 | 64,636 | May 13, 2014, 05:10 PM |
| PAKIANATHAN DEEPIKA | Director | Nov 12, 2013 | Buy | $16.00 | 3,022 | 48,352 | 20,337 | Nov 14, 2013, 04:33 PM |
| PAKIANATHAN DEEPIKA | Director | Nov 12, 2013 | Buy | $16.00 | 309,478 | 4,951,648 | 2,082,796 | Nov 14, 2013, 04:33 PM |
Load More Insider Transactions
Buy
Sale
Option Exercise
| Owner | Relationship | Date | Value($) |
| Paulson Richard A. | President and CEO | 04/04/2024 | 4,596 |
| Paulson Richard A. | President and CEO | 03/05/2024 | 4,645 |
| Rangwala Reshma | EVP & Chief Medical Officer | 03/01/2024 | 7,163 |
| Rangwala Reshma | EVP & Chief Medical Officer | 02/29/2024 | 18,330 |
| Poulton Stuart | EVP, Chief Development Officer | 03/01/2024 | 7,386 |
| Poulton Stuart | EVP, Chief Development Officer | 02/29/2024 | 19,084 |
| Mason Michael | EVP, CFO & Treasurer | 03/01/2024 | 7,394 |
| Mason Michael | EVP, CFO & Treasurer | 02/29/2024 | 32,394 |
| Mano Michael | SVP, General Counsel&Secretary | 03/01/2024 | 4,291 |
| Mano Michael | SVP, General Counsel&Secretary | 02/29/2024 | 19,858 |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | 03/01/2024 | 6,131 |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | 02/29/2024 | 25,553 |
| Paulson Richard A. | President and CEO | 03/01/2024 | 23,249 |
| Paulson Richard A. | President and CEO | 02/29/2024 | 94,150 |
| Mason Michael | EVP, CFO & Treasurer | 02/27/2024 | 3,369 |
| Poulton Stuart | EVP, Chief Development Officer | 02/15/2024 | 7,783 |
| Mason Michael | EVP, CFO & Treasurer | 02/06/2024 | 6,671 |
| Paulson Richard A. | President and CEO | 02/06/2024 | 6,365 |
| Paulson Richard A. | President and CEO | 01/04/2024 | 3,373 |
| Paulson Richard A. | President and CEO | 12/04/2023 | 2,861 |
| Paulson Richard A. | President and CEO | 11/06/2023 | 3,319 |
| Paulson Richard A. | President and CEO | 10/04/2023 | 4,558 |
| BOHLIN GAREN G | Director | 09/12/2023 | 49,985 |
| Paulson Richard A. | President and CEO | 09/05/2023 | 4,817 |
| Mason Michael | EVP, CFO & Treasurer | 09/01/2023 | 9,203 |
| Mano Michael | SVP, General Counsel&Secretary | 09/01/2023 | 5,176 |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | 09/01/2023 | 9,872 |
| Paulson Richard A. | President and CEO | 08/07/2023 | 6,402 |
| Poulton Stuart | EVP, Chief Development Officer | 07/28/2023 | 4,837 |
| Paulson Richard A. | President and CEO | 07/05/2023 | 6,085 |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | 06/08/2023 | 4,322 |
| Paulson Richard A. | President and CEO | 06/05/2023 | 7,922 |
| Mason Michael | EVP, CFO & Treasurer | 06/02/2023 | 1,401 |
| Paulson Richard A. | President and CEO | 05/04/2023 | 12,753 |
| Rangwala Reshma | EVP & Chief Medical Officer | 04/20/2023 | 27,416 |
| Paulson Richard A. | President and CEO | 04/04/2023 | 13,883 |
| Paulson Richard A. | President and CEO | 03/06/2023 | 11,079 |
| Mitchener Stephen | SVP, Chief Business Officer | 03/01/2023 | 19,257 |
| Mano Michael | SVP, General Counsel&Secretary | 03/01/2023 | 20,835 |
| Mano Michael | SVP, General Counsel&Secretary | 03/01/2023 | 20,835 |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | 03/01/2023 | 34,045 |
| Mason Michael | EVP, CFO & Treasurer | 03/01/2023 | 33,942 |
| Paulson Richard A. | President and CEO | 03/01/2023 | 100,064 |
| Poulton Stuart | EVP, Chief Development Officer | 02/15/2023 | 18,717 |
| Mason Michael | EVP, CFO & Treasurer | 02/06/2023 | 14,079 |
| Paulson Richard A. | President and CEO | 02/06/2023 | 13,430 |
| Paulson Richard A. | President and CEO | 01/04/2023 | 12,825 |
| Paulson Richard A. | President and CEO | 12/05/2022 | 18,043 |
| Paulson Richard A. | President and CEO | 11/04/2022 | 15,858 |
| Paulson Richard A. | President and CEO | 10/04/2022 | 20,475 |
| Paulson Richard A. | President and CEO | 09/08/2022 | 18,196 |
| Greene Barry E | Director | 08/11/2022 | 11,250 |
| Paulson Richard A. | President and CEO | 08/04/2022 | 10,367 |
| Paulson Richard A. | President and CEO | 07/08/2022 | 10,948 |
| Cheng Sohanya Roshan | Chief Commercial Officer | 06/13/2022 | 8,075 |
| PAKIANATHAN DEEPIKA | Director | 06/10/2022 | 7,844 |
| PAKIANATHAN DEEPIKA | Director | 06/09/2022 | 1,307,028 |
| PAKIANATHAN DEEPIKA | Director | 06/08/2022 | 2,119,926 |
| Paulson Richard A. | President and CEO | 06/07/2022 | 14,642 |
| Mason Michael | EVP, CFO, Treasurer | 06/03/2022 | 3,630 |
| Frenkel Ran | EVP, Chief Dev. Officer | 02/28/2022 | 17,025 |
| Mason Michael | EVP, CFO & Treasurer | 02/28/2022 | 24,550 |
| Shacham Sharon | Chief Scientific Officer | 02/28/2022 | 63,739 |
| Shacham Sharon | Chief Scientific Officer | 02/28/2022 | 63,739 |
| Shah Jatin | EVP, Chief Medical Officer | 02/17/2022 | 15,833 |
| Frenkel Ran | EVP, Chief Dev. Officer | 02/17/2022 | 35,509 |
| Shacham Sharon | Chief Scientific Officer | 02/17/2022 | 110,177 |
| Shacham Sharon | Chief Scientific Officer | 02/17/2022 | 110,068 |
| Kauffman Michael | Director | 02/17/2022 | 110,177 |
| Kauffman Michael | Director | 02/17/2022 | 110,068 |
| Shah Jatin | EVP, Chief Medical Officer | 02/07/2022 | 16,805 |
| Frenkel Ran | EVP, Chief Dev. Officer | 02/07/2022 | 19,635 |
| Mason Michael | EVP, CFO & Treasurer | 02/07/2022 | 38,925 |
| Kauffman Michael | Director | 02/07/2022 | 66,707 |
| Kauffman Michael | Director | 02/07/2022 | 66,144 |
| Shacham Sharon | Chief Scientific Officer | 02/07/2022 | 66,707 |
| Shacham Sharon | Chief Scientific Officer | 02/07/2022 | 66,144 |
| Mitchener Stephen | SVP, Chief Business Officer | 12/02/2021 | 3,338 |
| Shah Jatin | EVP, Chief Medical Officer | 07/12/2021 | 6,470 |
| Shah Jatin | EVP, Chief Medical Officer | 05/07/2021 | 199,992 |
| Shacham Sharon | President & CSO | 03/18/2021 | 49,553 |
| Kauffman Michael | Chief Executive Officer | 03/18/2021 | 49,553 |
| Shah Jatin | EVP, Chief Medical Officer | 02/18/2021 | 17,590 |
| Frenkel Ran | EVP, Chief Dev. Officer | 02/18/2021 | 42,818 |
| Shacham Sharon | President & CSO | 02/18/2021 | 140,822 |
| Shacham Sharon | President & CSO | 02/18/2021 | 140,822 |
| Kauffman Michael | Chief Executive Officer | 02/18/2021 | 140,822 |
| Kauffman Michael | Chief Executive Officer | 02/18/2021 | 140,822 |
| Lewis Tanya | EVP, Chief Reg. Affairs | 02/11/2021 | 31,752 |
| Shah Jatin | EVP, Chief Medical Officer | 02/11/2021 | 27,127 |
| Frenkel Ran | EVP, Chief Dev. Officer | 02/11/2021 | 31,752 |
| Mason Michael | SVP, CFO & Treasurer | 02/11/2021 | 44,354 |
| Shacham Sharon | President & CSO | 02/11/2021 | 102,441 |
| Shacham Sharon | President & CSO | 02/11/2021 | 103,077 |
| Kauffman Michael | Chief Executive Officer | 02/11/2021 | 103,077 |
| Kauffman Michael | Chief Executive Officer | 02/11/2021 | 102,441 |
| Mirza Mansoor Raza | Director | 12/18/2020 | 27,150 |
| Mirza Mansoor Raza | Director | 12/18/2020 | 90,000 |
| Mirza Mansoor Raza | Director | 12/07/2020 | 108,600 |
| Mirza Mansoor Raza | Director | 12/07/2020 | 321,383 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 12/01/2020 | 1,428,751 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 12/01/2020 | 2,402,227 |
| Lewis Tanya | EVP,Chief Reg.&Quality Officer | 10/30/2020 | 3,521 |
| Shah Jatin | EVP, Chief Medical Officer | 07/15/2020 | 11,462 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 11/02/2020 | 11,518 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 10/13/2020 | 362,537 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 10/13/2020 | 661,969 |
| Kauffman Michael | Chief Executive Officer | 10/12/2020 | 247 |
| Kauffman Michael | Chief Executive Officer | 10/12/2020 | 111,682 |
| Shacham Sharon | President & CSO | 10/12/2020 | 247 |
| Shacham Sharon | President & CSO | 10/12/2020 | 111,682 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 09/08/2020 | 65,753 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 09/08/2020 | 150,609 |
| DEMAREE JOHN | Chief Commercial Officer | 08/26/2020 | 109,012 |
| Kauffman Michael | Chief Executive Officer | 08/17/2020 | 49 |
| Kauffman Michael | Chief Executive Officer | 08/17/2020 | 22,155 |
| Shacham Sharon | President & CSO | 08/17/2020 | 49 |
| Shacham Sharon | President & CSO | 08/17/2020 | 22,155 |
| Kauffman Michael | Chief Executive Officer | 07/15/2020 | 247 |
| Kauffman Michael | Chief Executive Officer | 07/15/2020 | 145,723 |
| Shacham Sharon | President & CSO | 07/15/2020 | 247 |
| Shacham Sharon | President & CSO | 07/15/2020 | 145,723 |
| Kauffman Michael | Chief Executive Officer | 07/09/2020 | 35,640 |
| Kauffman Michael | Chief Executive Officer | 07/10/2020 | 35,640 |
| Kauffman Michael | Chief Executive Officer | 07/09/2020 | 146,487 |
| Kauffman Michael | Chief Executive Officer | 07/10/2020 | 142,539 |
| Shacham Sharon | President & CSO | 07/10/2020 | 35,640 |
| Shacham Sharon | President & CSO | 07/09/2020 | 35,640 |
| Shacham Sharon | President & CSO | 07/10/2020 | 142,539 |
| Shacham Sharon | President & CSO | 07/09/2020 | 146,487 |
| Kauffman Michael | Chief Executive Officer | 06/22/2020 | 247 |
| Kauffman Michael | Chief Executive Officer | 06/22/2020 | 150,000 |
| Shacham Sharon | President & CSO | 06/22/2020 | 247 |
| Shacham Sharon | President & CSO | 06/22/2020 | 150,000 |
| Kauffman Michael | Chief Executive Officer | 06/15/2020 | 247 |
| Kauffman Michael | Chief Executive Officer | 06/15/2020 | 122,779 |
| Shacham Sharon | President & CSO | 06/15/2020 | 247 |
| Shacham Sharon | President & CSO | 06/15/2020 | 122,779 |
| Kauffman Michael | Chief Executive Officer | 06/09/2020 | 35,640 |
| Kauffman Michael | Chief Executive Officer | 06/10/2020 | 35,640 |
| Kauffman Michael | Chief Executive Officer | 06/10/2020 | 135,944 |
| Kauffman Michael | Chief Executive Officer | 06/09/2020 | 138,745 |
| Shacham Sharon | President & CSO | 06/10/2020 | 35,640 |
| Shacham Sharon | President & CSO | 06/09/2020 | 35,640 |
| Shacham Sharon | President & CSO | 06/10/2020 | 135,944 |
| Shacham Sharon | President & CSO | 06/09/2020 | 138,745 |
| Kauffman Michael | Chief Executive Officer | 05/18/2020 | 247 |
| Kauffman Michael | Chief Executive Officer | 05/15/2020 | 247 |
| Kauffman Michael | Chief Executive Officer | 05/18/2020 | 150,000 |
| Kauffman Michael | Chief Executive Officer | 05/15/2020 | 139,840 |
| Shacham Sharon | President & CSO | 05/15/2020 | 247 |
| Shacham Sharon | President & CSO | 05/18/2020 | 247 |
| Shacham Sharon | President & CSO | 05/15/2020 | 139,840 |
| Shacham Sharon | President & CSO | 05/18/2020 | 150,000 |
| Frenkel Ran | Chief Dev Operations Officer | 05/07/2020 | 39,480 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 05/07/2020 | 19,267 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 05/07/2020 | 190,627 |
| Shacham Sharon | President & CSO | 05/07/2020 | 35,640 |
| Shacham Sharon | President & CSO | 05/07/2020 | 35,640 |
| Shacham Sharon | President & CSO | 05/07/2020 | 147,205 |
| Shacham Sharon | President & CSO | 05/07/2020 | 147,209 |
| Kauffman Michael | Chief Executive Officer | 05/07/2020 | 35,640 |
| Kauffman Michael | Chief Executive Officer | 05/07/2020 | 35,640 |
| Kauffman Michael | Chief Executive Officer | 05/07/2020 | 147,205 |
| Kauffman Michael | Chief Executive Officer | 05/07/2020 | 147,209 |
| Kauffman Michael | Chief Executive Officer | 04/08/2020 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 04/09/2020 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 04/08/2020 | 186,115 |
| Kauffman Michael | Chief Executive Officer | 04/09/2020 | 206,404 |
| Shacham Sharon | President & CSO | 04/08/2020 | 47,520 |
| Shacham Sharon | President & CSO | 04/09/2020 | 47,520 |
| Shacham Sharon | President & CSO | 04/08/2020 | 186,115 |
| Shacham Sharon | President & CSO | 04/09/2020 | 206,404 |
| Greene Barry E | Director | 03/13/2020 | 100 |
| Shacham Sharon | President & CSO | 03/10/2020 | 47,520 |
| Shacham Sharon | President & CSO | 03/09/2020 | 47,520 |
| Shacham Sharon | President & CSO | 03/10/2020 | 222,186 |
| Shacham Sharon | President & CSO | 03/09/2020 | 225,195 |
| Kauffman Michael | Chief Executive Officer | 03/09/2020 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 03/10/2020 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 03/09/2020 | 225,195 |
| Kauffman Michael | Chief Executive Officer | 03/10/2020 | 222,186 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 03/02/2020 | 275,335 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 03/02/2020 | 672,279 |
| Mirza Mansoor Raza | Director | 03/02/2020 | 40,300 |
| Mirza Mansoor Raza | Director | 03/02/2020 | 117,500 |
| Shah Jatin | EVP, Chief Medical Officer | 02/19/2020 | 22,663 |
| Frenkel Ran | Chief Dev Operations Officer | 02/19/2020 | 49,034 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 02/19/2020 | 48,803 |
| Shacham Sharon | President & CSO | 02/19/2020 | 145,321 |
| Shacham Sharon | President & CSO | 02/19/2020 | 145,321 |
| Kauffman Michael | Chief Executive Officer | 02/19/2020 | 145,321 |
| Kauffman Michael | Chief Executive Officer | 02/19/2020 | 145,321 |
| Shacham Sharon | President & CSO | 02/11/2020 | 47,520 |
| Shacham Sharon | President & CSO | 02/10/2020 | 47,520 |
| Shacham Sharon | President & CSO | 02/11/2020 | 174,294 |
| Shacham Sharon | President & CSO | 02/10/2020 | 169,327 |
| Kauffman Michael | Chief Executive Officer | 02/10/2020 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 02/11/2020 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 02/11/2020 | 174,294 |
| Kauffman Michael | Chief Executive Officer | 02/10/2020 | 169,327 |
| Mirza Mansoor Raza | Director | 01/09/2020 | 16,571 |
| Mirza Mansoor Raza | Director | 01/09/2020 | 41,120 |
| Kauffman Michael | Chief Executive Officer | 01/08/2020 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 01/09/2020 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 01/09/2020 | 191,880 |
| Kauffman Michael | Chief Executive Officer | 01/08/2020 | 185,705 |
| Shacham Sharon | President & CSO | 01/08/2020 | 47,520 |
| Shacham Sharon | President & CSO | 01/09/2020 | 47,520 |
| Shacham Sharon | President & CSO | 01/09/2020 | 191,880 |
| Shacham Sharon | President & CSO | 01/08/2020 | 185,705 |
| Mirza Mansoor Raza | Director | 12/27/2019 | 23,729 |
| Mirza Mansoor Raza | Director | 12/27/2019 | 58,880 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 12/27/2019 | 51,950 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 12/27/2019 | 100,000 |
| Mirza Mansoor Raza | Director | 12/18/2019 | 18,000 |
| Mirza Mansoor Raza | Director | 12/18/2019 | 208,236 |
| Mirza Mansoor Raza | Director | 12/09/2019 | 58,360 |
| Mirza Mansoor Raza | Director | 12/09/2019 | 176,034 |
| Kauffman Michael | Chief Executive Officer | 12/09/2019 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 12/10/2019 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 12/09/2019 | 170,210 |
| Kauffman Michael | Chief Executive Officer | 12/10/2019 | 159,896 |
| Shacham Sharon | President & CSO | 12/10/2019 | 47,520 |
| Shacham Sharon | President & CSO | 12/09/2019 | 47,520 |
| Shacham Sharon | President & CSO | 12/10/2019 | 159,896 |
| Shacham Sharon | President & CSO | 12/09/2019 | 170,210 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 12/06/2019 | 84,650 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 12/06/2019 | 226,908 |
| Kauffman Michael | Chief Executive Officer | 11/08/2019 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 11/11/2019 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 11/11/2019 | 147,610 |
| Kauffman Michael | Chief Executive Officer | 11/08/2019 | 146,254 |
| Shacham Sharon | President & CSO | 11/08/2019 | 47,520 |
| Shacham Sharon | President & CSO | 11/11/2019 | 47,520 |
| Shacham Sharon | President & CSO | 11/11/2019 | 147,610 |
| Shacham Sharon | President & CSO | 11/08/2019 | 146,254 |
| Shacham Sharon | President & CSO | 11/01/2019 | 47,520 |
| Shacham Sharon | President & CSO | 11/01/2019 | 47,520 |
| Shacham Sharon | President & CSO | 11/01/2019 | 120,000 |
| Shacham Sharon | President & CSO | 11/01/2019 | 120,000 |
| Kauffman Michael | Chief Executive Officer | 11/01/2019 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 11/01/2019 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 11/01/2019 | 120,000 |
| Kauffman Michael | Chief Executive Officer | 11/01/2019 | 120,000 |
| Kauffman Michael | Chief Executive Officer | 09/16/2019 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 09/16/2019 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 09/16/2019 | 120,000 |
| Kauffman Michael | Chief Executive Officer | 09/16/2019 | 120,000 |
| Shacham Sharon | President & CSO | 09/16/2019 | 47,520 |
| Shacham Sharon | President & CSO | 09/16/2019 | 47,520 |
| Shacham Sharon | President & CSO | 09/16/2019 | 120,000 |
| Shacham Sharon | President & CSO | 09/16/2019 | 120,000 |
| Chione Ltd | 10% Owner | 02/28/2019 | 619,114 |
| Chione Ltd | 10% Owner | 02/26/2019 | 617,210 |
| Chione Ltd | 10% Owner | 02/25/2019 | 3,994,880 |
| Chione Ltd | 10% Owner | 02/27/2019 | 2,515,834 |
| Kauffman Michael | Chief Executive Officer | 01/07/2019 | 412 |
| Kauffman Michael | Chief Executive Officer | 01/07/2019 | 127,824 |
| Shacham Sharon | President & CSO | 01/07/2019 | 412 |
| Shacham Sharon | President & CSO | 01/07/2019 | 127,824 |
| Kauffman Michael | Chief Executive Officer | 12/07/2018 | 412 |
| Kauffman Michael | Chief Executive Officer | 12/07/2018 | 126,423 |
| Shacham Sharon | President & CSO | 12/07/2018 | 412 |
| Shacham Sharon | President & CSO | 12/07/2018 | 126,423 |
| Shacham Sharon | President & CSO | 11/26/2018 | 45,619 |
| Shacham Sharon | President & CSO | 11/26/2018 | 105,600 |
| Kauffman Michael | Chief Executive Officer | 11/26/2018 | 45,619 |
| Kauffman Michael | Chief Executive Officer | 11/26/2018 | 105,600 |
| Shacham Sharon | President & CSO | 11/19/2018 | 1,901 |
| Shacham Sharon | President & CSO | 11/19/2018 | 4,455 |
| Kauffman Michael | Chief Executive Officer | 11/19/2018 | 1,901 |
| Kauffman Michael | Chief Executive Officer | 11/19/2018 | 4,455 |
| Kauffman Michael | Chief Executive Officer | 11/07/2018 | 412 |
| Kauffman Michael | Chief Executive Officer | 11/07/2018 | 145,592 |
| Shacham Sharon | President & CSO | 11/07/2018 | 412 |
| Shacham Sharon | President & CSO | 11/07/2018 | 145,592 |
| Shacham Sharon | President & CSO | 10/18/2018 | 47,520 |
| Shacham Sharon | President & CSO | 10/18/2018 | 126,304 |
| Kauffman Michael | Chief Executive Officer | 10/18/2018 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 10/18/2018 | 126,304 |
| Kauffman Michael | Chief Executive Officer | 10/08/2018 | 412 |
| Kauffman Michael | Chief Executive Officer | 10/08/2018 | 196,832 |
| Shacham Sharon | President & CSO | 10/08/2018 | 412 |
| Shacham Sharon | President & CSO | 10/08/2018 | 196,832 |
| Shacham Sharon | President & CSO | 09/18/2018 | 47,520 |
| Shacham Sharon | President & CSO | 09/18/2018 | 182,615 |
| Kauffman Michael | Chief Executive Officer | 09/18/2018 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 09/18/2018 | 182,615 |
| Kauffman Michael | Chief Executive Officer | 09/07/2018 | 412 |
| Kauffman Michael | Chief Executive Officer | 09/07/2018 | 241,384 |
| Shacham Sharon | President & CSO | 09/07/2018 | 412 |
| Shacham Sharon | President & CSO | 09/07/2018 | 241,384 |
| Chione Ltd | 10% Owner | 09/05/2018 | 3,370,256 |
| Chione Ltd | 10% Owner | 09/06/2018 | 98,474 |
| Chione Ltd | 10% Owner | 09/04/2018 | 824,072 |
| Chione Ltd | 10% Owner | 08/31/2018 | 241,396 |
| Chione Ltd | 10% Owner | 08/30/2018 | 4,199,900 |
| Mirza Mansoor Raza | Director | 08/30/2018 | 4,810 |
| Mirza Mansoor Raza | Director | 08/30/2018 | 52,500 |
| Mirza Mansoor Raza | Director | 08/29/2018 | 3,713 |
| Mirza Mansoor Raza | Director | 08/29/2018 | 50,000 |
| Chione Ltd | 10% Owner | 08/29/2018 | 3,918,280 |
| Chione Ltd | 10% Owner | 08/27/2018 | 259,776 |
| Shacham Sharon | President & CSO | 08/20/2018 | 47,520 |
| Shacham Sharon | President & CSO | 08/20/2018 | 174,568 |
| Kauffman Michael | Chief Executive Officer | 08/20/2018 | 47,520 |
| Kauffman Michael | Chief Executive Officer | 08/20/2018 | 174,568 |
| Chione Ltd | 10% Owner | 08/10/2018 | 12,987 |
| Chione Ltd | 10% Owner | 08/09/2018 | 1,248,782 |
| Chione Ltd | 10% Owner | 08/08/2018 | 52,098 |
| Chione Ltd | 10% Owner | 08/07/2018 | 197,197 |
| Kauffman Michael | Chief Executive Officer | 08/07/2018 | 412 |
| Kauffman Michael | Chief Executive Officer | 08/07/2018 | 225,556 |
| Shacham Sharon | President & CSO | 08/07/2018 | 412 |
| Shacham Sharon | President & CSO | 08/07/2018 | 225,556 |
| Chione Ltd | 10% Owner | 07/25/2018 | 16,571 |
| Chione Ltd | 10% Owner | 07/24/2018 | 170,342 |
| Chione Ltd | 10% Owner | 07/23/2018 | 373,222 |
| Chione Ltd | 10% Owner | 07/19/2018 | 1,889,940 |
| Chione Ltd | 10% Owner | 07/20/2018 | 513,805 |
| Shacham Sharon | President & CSO | 07/18/2018 | 21,678 |
| Shacham Sharon | President & CSO | 07/18/2018 | 182,686 |
| Kauffman Michael | Chief Executive Officer | 07/18/2018 | 21,678 |
| Kauffman Michael | Chief Executive Officer | 07/18/2018 | 182,686 |
| Chione Ltd | 10% Owner | 07/16/2018 | 49,161 |
| Chione Ltd | 10% Owner | 07/18/2018 | 556,005 |
| Chione Ltd | 10% Owner | 07/17/2018 | 320,901 |
| Kauffman Michael | Chief Executive Officer | 07/09/2018 | 412 |
| Kauffman Michael | Chief Executive Officer | 07/09/2018 | 233,990 |
| Shacham Sharon | President & CSO | 07/09/2018 | 412 |
| Shacham Sharon | President & CSO | 07/09/2018 | 233,990 |
| Shacham Sharon | President & CSO | 06/18/2018 | 2,640 |
| Shacham Sharon | President & CSO | 06/18/2018 | 186,558 |
| Kauffman Michael | Chief Executive Officer | 06/18/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 06/18/2018 | 186,558 |
| Kauffman Michael | Chief Executive Officer | 06/07/2018 | 2,570 |
| Kauffman Michael | Chief Executive Officer | 06/07/2018 | 172,991 |
| Shacham Sharon | President & CSO | 06/07/2018 | 2,570 |
| Shacham Sharon | President & CSO | 06/07/2018 | 172,991 |
| Shacham Sharon | President & CSO | 05/18/2018 | 2,640 |
| Shacham Sharon | President & CSO | 05/18/2018 | 193,870 |
| Kauffman Michael | Chief Executive Officer | 05/18/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 05/18/2018 | 193,870 |
| Mirza Mansoor Raza | Director | 05/10/2018 | 2,146 |
| Mirza Mansoor Raza | Director | 05/10/2018 | 36,000 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 05/10/2018 | 36,024 |
| Kauffman Michael | Chief Executive Officer | 05/07/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 05/07/2018 | 167,747 |
| Shacham Sharon | President & CSO | 05/07/2018 | 2,640 |
| Shacham Sharon | President & CSO | 05/07/2018 | 167,747 |
| Shacham Sharon | President & CSO | 04/18/2018 | 2,640 |
| Shacham Sharon | President & CSO | 04/18/2018 | 147,878 |
| Kauffman Michael | Chief Executive Officer | 04/18/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 04/18/2018 | 147,878 |
| Kauffman Michael | Chief Executive Officer | 04/09/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 04/09/2018 | 124,829 |
| Shacham Sharon | President & CSO | 04/09/2018 | 2,640 |
| Shacham Sharon | President & CSO | 04/09/2018 | 124,829 |
| Shacham Sharon | President & CSO | 03/19/2018 | 2,640 |
| Shacham Sharon | President & CSO | 03/19/2018 | 152,895 |
| Kauffman Michael | Chief Executive Officer | 03/19/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 03/19/2018 | 152,895 |
| Mirza Mansoor Raza | Director | 03/12/2018 | 660 |
| Mirza Mansoor Raza | Director | 03/12/2018 | 42,525 |
| Kauffman Michael | Chief Executive Officer | 03/07/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 03/07/2018 | 161,463 |
| Shacham Sharon | President & CSO | 03/07/2018 | 2,640 |
| Shacham Sharon | President & CSO | 03/07/2018 | 161,463 |
| Mirza Mansoor Raza | Director | 03/05/2018 | 660 |
| Mirza Mansoor Raza | Director | 03/05/2018 | 40,000 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 03/05/2018 | 40,076 |
| Shacham Sharon | President & CSO | 02/20/2018 | 2,640 |
| Shacham Sharon | President & CSO | 02/20/2018 | 147,872 |
| Kauffman Michael | Chief Executive Officer | 02/20/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 02/20/2018 | 147,872 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 02/16/2018 | 22,298 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 02/15/2018 | 15,229 |
| Mirza Mansoor Raza | Director | 02/08/2018 | 396 |
| Mirza Mansoor Raza | Director | 02/08/2018 | 21,000 |
| Mirza Mansoor Raza | Director | 02/07/2018 | 396 |
| Mirza Mansoor Raza | Director | 02/07/2018 | 19,500 |
| Primiano Christopher Brett | EVP, CBO, GC & Secretary | 02/07/2018 | 19,500 |
| Kauffman Michael | Chief Executive Officer | 02/07/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 02/07/2018 | 125,048 |
| Shacham Sharon | President & CSO | 02/07/2018 | 2,640 |
| Shacham Sharon | President & CSO | 02/07/2018 | 125,048 |
| Shacham Sharon | President & CSO | 01/18/2018 | 2,640 |
| Shacham Sharon | President & CSO | 01/18/2018 | 100,882 |
| Kauffman Michael | Chief Executive Officer | 01/18/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 01/18/2018 | 100,882 |
| Kauffman Michael | Chief Executive Officer | 01/08/2018 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 01/08/2018 | 100,769 |
| Shacham Sharon | President & CSO | 01/08/2018 | 2,640 |
| Shacham Sharon | President & CSO | 01/08/2018 | 100,769 |
| Shacham Sharon | President & CSO | 12/18/2017 | 2,640 |
| Shacham Sharon | President & CSO | 12/18/2017 | 91,553 |
| Kauffman Michael | Chief Executive Officer | 12/18/2017 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 12/18/2017 | 91,553 |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | 12/12/2017 | 111,180 |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | 12/12/2017 | 168,616 |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | 12/11/2017 | 109,256 |
| Kauffman Michael | Chief Executive Officer | 12/07/2017 | 2,640 |
| Kauffman Michael | Chief Executive Officer | 12/07/2017 | 103,903 |
| Shacham Sharon | President & CSO | 12/07/2017 | 2,640 |
| Shacham Sharon | President & CSO | 12/07/2017 | 103,903 |
| Frenkel Ran | Chief Dev Operations Officer | 11/07/2017 | 55,755 |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | 11/07/2017 | 55,755 |
| Mirza Mansoor Raza | Director | 10/02/2017 | 528 |
| Mirza Mansoor Raza | Director | 10/02/2017 | 24,000 |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | 10/02/2017 | 18,000 |
| Mirza Mansoor Raza | Director | 09/15/2017 | 761 |
| Mirza Mansoor Raza | Director | 09/15/2017 | 31,702 |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | 09/15/2017 | 22,000 |
| Mirza Mansoor Raza | Director | 09/11/2017 | 31 |
| Mirza Mansoor Raza | Director | 09/11/2017 | 1,298 |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | 06/26/2017 | 8,071 |
| Primiano Christopher Brett | SVP, OPS, BUS DEV, GC & SEC | 08/29/2017 | 21,950 |
| Frenkel Ran | Chief Dev Operations Officer | 11/14/2016 | 33,286 |
| Renz Justin A | EVP, CFO & Treasurer | 11/09/2016 | 35,544 |
| Primiano Christopher Brett | SVP,CORP DEV,GEN COUNSEL&SEC. | 11/09/2016 | 35,544 |
| Chione Ltd | 10% Owner | 06/23/2016 | 151,083 |
| Chione Ltd | 10% Owner | 06/13/2016 | 60,214 |
| Chione Ltd | 10% Owner | 06/08/2016 | 145,186 |
| Chione Ltd | 10% Owner | 06/09/2016 | 274,098 |
| Chione Ltd | 10% Owner | 06/07/2016 | 185,086 |
| Chione Ltd | 10% Owner | 06/06/2016 | 184,464 |
| Chione Ltd | 10% Owner | 06/02/2016 | 172,244 |
| Chione Ltd | 10% Owner | 05/27/2016 | 383,200 |
| Chione Ltd | 10% Owner | 06/01/2016 | 169,327 |
| Chione Ltd | 10% Owner | 05/31/2016 | 165,072 |
| Chione Ltd | 10% Owner | 05/26/2016 | 174,287 |
| Chione Ltd | 10% Owner | 05/25/2016 | 274,541 |
| Chione Ltd | 10% Owner | 05/23/2016 | 297,414 |
| Chione Ltd | 10% Owner | 05/20/2016 | 340,748 |
| Chione Ltd | 10% Owner | 05/19/2016 | 163,644 |
| Chione Ltd | 10% Owner | 05/17/2016 | 275,480 |
| Chione Ltd | 10% Owner | 05/18/2016 | 244,488 |
| Chione Ltd | 10% Owner | 05/16/2016 | 80,065 |
| Chione Ltd | 10% Owner | 05/13/2016 | 3,203 |
| Chione Ltd | 10% Owner | 05/11/2016 | 99,860 |
| Chione Ltd | 10% Owner | 05/10/2016 | 162,788 |
| Mirza Mansoor Raza | Director | 12/08/2015 | 844 |
| Mirza Mansoor Raza | Director | 12/08/2015 | 225,136 |
| Frenkel Ran | EVP, WW Development Operations | 04/07/2015 | 66,000 |
| Frenkel Ran | EVP, WW Development Operations | 04/06/2015 | 29,430 |
| Greene Barry E | Director | 04/02/2015 | 87,938 |
| Renz Justin A | EVP, CFO & Treasurer | 04/02/2015 | 148,557 |
| WEG KENNETH E | Director | 04/02/2015 | 147,760 |
| Shacham Sharon | President & CSO | 01/12/2015 | 825,000 |
| Shacham Sharon | President & CSO | 01/12/2015 | 825,000 |
| PAKIANATHAN DEEPIKA | Director | 01/12/2015 | 14,520 |
| PAKIANATHAN DEEPIKA | Director | 01/12/2015 | 1,485,462 |
| Kauffman Michael | Chief Executive Officer | 01/12/2015 | 825,000 |
| Kauffman Michael | Chief Executive Officer | 01/12/2015 | 825,000 |
| Mirza Mansoor Raza | Director | 12/02/2014 | 165 |
| Mirza Mansoor Raza | Director | 12/01/2014 | 51 |
| Mirza Mansoor Raza | Director | 12/02/2014 | 225,881 |
| Mirza Mansoor Raza | Director | 12/01/2014 | 209,286 |
| Chione Ltd | 10% Owner | 11/26/2014 | 2,330,917 |
| Chione Ltd | 10% Owner | 12/01/2014 | 8,273,223 |
| Chione Ltd | 10% Owner | 11/28/2014 | 1,054,520 |
| Chione Ltd | 10% Owner | 11/25/2014 | 5,393,104 |
| Chione Ltd | 10% Owner | 11/24/2014 | 3,133,800 |
| Chione Ltd | 10% Owner | 11/21/2014 | 1,767,143 |
| Chione Ltd | 10% Owner | 11/19/2014 | 2,411,021 |
| Chione Ltd | 10% Owner | 11/18/2014 | 233,770 |
| Chione Ltd | 10% Owner | 11/11/2014 | 2,299,878 |
| Chione Ltd | 10% Owner | 11/10/2014 | 2,820,802 |
| Chione Ltd | 10% Owner | 11/12/2014 | 1,907,348 |
| Mirza Mansoor Raza | Director | 11/10/2014 | 225,256 |
| Chione Ltd | 10% Owner | 11/06/2014 | 7,475,815 |
| Chione Ltd | 10% Owner | 11/04/2014 | 4,012,349 |
| Mirza Mansoor Raza | Director | 11/03/2014 | 204,750 |
| Mirza Mansoor Raza | Director | 10/29/2014 | 140,161 |
| Mirza Mansoor Raza | Director | 10/20/2014 | 52,560 |
| Chione Ltd | 10% Owner | 09/26/2014 | 8,529,202 |
| Czernik Marcin | 10% Owner | 09/26/2014 | 2,127,200 |
| Czernik Marcin | 10% Owner | 09/24/2014 | 907,133 |
| Czernik Marcin | 10% Owner | 09/18/2014 | 111,556 |
| Czernik Marcin | 10% Owner | 09/17/2014 | 385,270 |
| Chione Ltd | 10% Owner | 09/12/2014 | 177,325 |
| Czernik Marcin | 10% Owner | 09/08/2014 | 1,423,623 |
| Czernik Marcin | 10% Owner | 09/04/2014 | 487,095 |
| Czernik Marcin | 10% Owner | 08/26/2014 | 857,304 |
| Czernik Marcin | 10% Owner | 08/27/2014 | 838,431 |
| Czernik Marcin | 10% Owner | 08/25/2014 | 167,151 |
| Czernik Marcin | 10% Owner | 08/18/2014 | 124,132 |
| Czernik Marcin | 10% Owner | 08/15/2014 | 306,359 |
| Czernik Marcin | 10% Owner | 08/14/2014 | 7,609 |
| Czernik Marcin | 10% Owner | 08/11/2014 | 1,379,350 |
| Czernik Marcin | 10% Owner | 07/30/2014 | 1,540,115 |
| Czernik Marcin | 10% Owner | 07/30/2014 | 780,931 |
| Chione Ltd | 10% Owner | 07/29/2014 | 1,055,853 |
| Plio Ltd | 10% Owner | 07/23/2014 | 1,777,185 |
| Plio Ltd | 10% Owner | 07/23/2014 | 17,771,851 |
| Shacham Sharon | President & CSO | 07/02/2014 | 4,250,000 |
| Shacham Sharon | President & CSO | 07/02/2014 | 4,250,000 |
| Kauffman Michael | Chief Executive Officer | 07/02/2014 | 4,250,000 |
| Kauffman Michael | Chief Executive Officer | 07/02/2014 | 4,250,000 |
| Shacham Sharon | President & CSO | 06/18/2014 | 431,523 |
| Shacham Sharon | President & CSO | 06/17/2014 | 403,635 |
| Kauffman Michael | Chief Executive Officer | 06/18/2014 | 431,523 |
| Kauffman Michael | Chief Executive Officer | 06/17/2014 | 403,635 |
| PAKIANATHAN DEEPIKA | Director | 05/22/2014 | 516,769 |
| PAKIANATHAN DEEPIKA | Director | 05/21/2014 | 23,470 |
| PAKIANATHAN DEEPIKA | Director | 05/21/2014 | 2,403,404 |
| PAKIANATHAN DEEPIKA | Director | 05/23/2014 | 450 |
| PAKIANATHAN DEEPIKA | Director | 05/23/2014 | 46,334 |
| PAKIANATHAN DEEPIKA | Director | 05/22/2014 | 5,035 |
| Brannelly Paul | SVP, FINANCE & ADMIN, TREAS | 05/15/2014 | 18,165 |
| Brannelly Paul | SVP, FINANCE & ADMIN, TREAS | 05/14/2014 | 21,544 |
| Primiano Christopher Brett | VP, GEN COUNSEL & SECRETARY | 05/13/2014 | 26,750 |
| Brannelly Paul | SVP, FINANCE & ADMIN, TREAS | 05/13/2014 | 28,057 |
| PAKIANATHAN DEEPIKA | Director | 11/12/2013 | 48,352 |
| PAKIANATHAN DEEPIKA | Director | 11/12/2013 | 4,951,648 |
Load More Insider Transactions
FUNDS WITH A POSITION IN KARYOPHARM THERAPEUTICS INC
| Fund | # Shares Owned | % of Portfolio | % Change | Investing Style |
|---|---|---|---|---|
| BLACKROCK INC. | 10,071,677 | 0.00022% | -9.15% | Other |
| PALO ALTO INVESTORS LP | 5,102,193 | 0.4% | -10.11% | Other |
| GEODE CAPITAL MANAGEMENT, LLC | 2,382,428 | 0.00022% | 4.17% | Other |
| RENAISSANCE TECHNOLOGIES LLC | 1,964,377 | 0.00263% | 168.95% | Other |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,663,300 | 0.00298% | New | Other |
| UBS OCONNOR LLC | 802,327 | 0.05% | -8.48% | Value |
| D. E. SHAW & CO., INC. | 617,216 | 0.00047% | -0.91% | Other |
| AQR CAPITAL MANAGEMENT LLC | 598,142 | 0.00097% | 19.2% | Other |
| CANDRIAM S.C.A. | 530,694 | 0.00317% | -53.48% | Other |
| UBS OCONNOR LLC | 300,000 (Call) | 0.00054% | No change | Value |
CHANGE IN SHARES OUTSTANDING FOR KARYOPHARM THERAPEUTICS INC
STOCK BUYBACKS FOR KARYOPHARM THERAPEUTICS INC
Period of Report
Previous Period
% Change in Shares
10-K/10-Q Filings
Quarter
Load More
Period of Report: 12/31/2023
10-K/10-Q Filings: View
Previous Period
% Change in Shares
Quarter
09/30/2023
0.34%
1Q
06/30/2023
0.51%
2Q
03/31/2023
1.15%
3Q
12/31/2022
27.50%
4Q
09/30/2022
43.11%
5Q
06/30/2022
44.11%
6Q
03/31/2022
47.98%
7Q
12/31/2021
51.68%
8Q
09/30/2021
52.11%
9Q
06/30/2021
52.66%
10Q
03/31/2021
54.04%
11Q
12/31/2020
55.66%
12Q
09/30/2020
56.24%
13Q
06/30/2020
56.73%
14Q
03/31/2020
69.73%
15Q
12/31/2019
79.55%
16Q
Load More
BUYBACK ANNOUNCEMENT(S) FOR KARYOPHARM THERAPEUTICS INC
LOADING...