Exelixis Inc. (EXEL) NASDAQ
$22.61 0.12 (0.51%)
Market Cap: $6.82B
As of 04/19/24 10:07 AM EDT. Market open.
Exelixis Inc. (EXEL)
NASDAQ
$22.61
0.12 (0.51%)
Market Cap: $6.82B
As of 04/19/24 10:07 AM EDT. Market open.
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exelixis is a biopharmaceutical company focused on developing and commercializing small molecule therapies with the potential to improve the treatment of cancer. over the past decade, we have established a broad development platform, laying the foundation for our continued efforts to bring new therapies for cancer to patients in need. our first commercial product, cometriq® (cabozantinib), ... read more
exelixis is a biopharmaceutical company focused on developing and commercializing small molecule therapies with the potential to improve the treatment of cancer. over the past decade, we have established a broad development platform, laying the foundation for our continued efforts to bring new therapies for cancer to patients in need. our first commercial product, cometriq® (cabozantinib), received its initial regulatory approval in late 2012. we are committed to excellence in all aspects of our business and are dedicated to improving the care of, and outcomes for, patients with cancer. for more information about the company and potential job opportunities, please visit our website at www.exelixis.com. read less
COMPANY PROFILE
Sector
Professional, Scientific, and Technical Services
Industry
Research and Development in Biotechnology (except Nanobiotechnology)
CEO Compensation (Base)
$945,080
CEO Compensation (Total)
$7.98M
Sector
Professional, Scientific, and Technical Services
Industry
Research and Development in Biotechnology (except Nanobiotechnology)
Full Time Employees
1,493
CEO Compensation (Base)
$945,080
CEO Compensation (Total)
$7.98M
URL
Address
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PRICE CHART FOR EXELIXIS INC
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NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
$22.47
Previous Close
$22.49
Days Range
$22.46 - $23.23
52 week range
$18.08 - $24.34
Volume
227,407
Avg. Volume (30 days)
2,057,133
Market Cap
$6.82B
Dividend Yield
-
P/E
32.82
Shares Outstanding
303,194,259
Open
$22.47
Previous Close
$22.49
Days Range
$22.46 - $23.23
52 week range
$18.08 - $24.34
Volume
227,407
Avg. Volume (30 days)
2,057,133
Market Cap
$6.82B
Dividend Yield
-
P/E
32.82
Shares Outstanding
303,194,259
FINANCIAL STATEMENTS FOR EXELIXIS INC
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INSIDER TRANSACTIONS FOR EXELIXIS INC
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| Garber Alan M | Director | Mar 21, 2024 | Option Exercise | $19.57 | 23,491 | 459,719 | 54,908 | Mar 25, 2024, 07:31 PM |
| Garber Alan M | Director | Mar 21, 2024 | Sale | $24.01 | 19,205 | 461,112 | 35,703 | Mar 25, 2024, 07:31 PM |
| Haley Patrick J. | EVP, Commercial | Feb 23, 2024 | Sale | $21.45 | 47,020 | 1,008,579 | 384,866 | Feb 27, 2024, 06:58 PM |
| JOHNSON DAVID EDWARD | Director | Feb 21, 2024 | Buy | $20.70 | 190,000 | 3,932,734 | 1,100,730 | Feb 22, 2024, 05:08 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | Feb 15, 2024 | Option Exercise | $20.39 | 10,630 | 216,746 | 479,031 | Feb 16, 2024, 07:21 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 11, 2024 | Option Exercise | $22.86 | 63,717 | 1,456,571 | 796,657 | Jan 16, 2024, 08:50 PM |
| Senner Christopher J. | EVP and CFO | Jan 11, 2024 | Option Exercise | $22.86 | 21,862 | 499,765 | 669,869 | Jan 16, 2024, 08:50 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Jan 11, 2024 | Option Exercise | $22.86 | 13,061 | 298,574 | 591,702 | Jan 16, 2024, 08:50 PM |
| Haley Patrick J. | EVP, Commercial | Jan 11, 2024 | Option Exercise | $22.86 | 13,613 | 311,193 | 368,536 | Jan 16, 2024, 08:50 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | Jan 11, 2024 | Option Exercise | $22.86 | 11,606 | 265,313 | 489,661 | Jan 16, 2024, 08:50 PM |
| Haley Patrick J. | EVP, Commercial | Dec 14, 2023 | Option Exercise | $16.29 | 50,000 | 814,500 | 357,687 | Dec 14, 2023, 07:56 PM |
| Haley Patrick J. | EVP, Commercial | Dec 14, 2023 | Sale | $23.35 | 50,000 | 1,167,500 | 307,687 | Dec 14, 2023, 07:56 PM |
| Haley Patrick J. | EVP, Commercial | Dec 12, 2023 | Sale | $22.50 | 14,149 | 318,353 | 307,687 | Dec 14, 2023, 07:56 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Dec 13, 2023 | Sale | $23.01 | 25,000 | 575,250 | 533,345 | Dec 14, 2023, 07:55 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Nov 30, 2023 | Sale | $22.01 | 25,000 | 550,250 | 583,345 | Dec 04, 2023, 06:22 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Dec 04, 2023 | Sale | $22.06 | 25,000 | 551,500 | 558,345 | Dec 04, 2023, 06:22 PM |
| JOHNSON DAVID EDWARD | Director | Nov 27, 2023 | Buy | $21.61 | 120,409 | 2,602,039 | 910,730 | Nov 29, 2023, 04:30 PM |
| JOHNSON DAVID EDWARD | Director | Nov 27, 2023 | Sale | $21.61 | 120,409 | 2,602,039 | 790,321 | Nov 29, 2023, 04:30 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 06, 2023 | Option Exercise | $22.27 | 46,608 | 1,037,960 | 726,893 | Sep 08, 2023, 09:28 PM |
| Senner Christopher J. | EVP and CFO | Sep 06, 2023 | Option Exercise | $22.27 | 17,147 | 381,864 | 611,545 | Sep 08, 2023, 09:26 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | Sep 06, 2023 | Option Exercise | $22.27 | 12,560 | 279,711 | 438,043 | Sep 08, 2023, 09:25 PM |
| Haley Patrick J. | EVP, Commercial | Sep 06, 2023 | Option Exercise | $22.27 | 14,354 | 319,664 | 321,836 | Sep 08, 2023, 09:24 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Sep 06, 2023 | Option Exercise | $22.27 | 14,354 | 319,664 | 608,345 | Sep 08, 2023, 09:22 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | Aug 30, 2023 | Sale | $22.47 | 4,600 | 103,362 | 399,943 | Sep 01, 2023, 08:15 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 28, 2023 | Option Exercise | $22.18 | 303,779 | 6,737,818 | 641,717 | Aug 30, 2023, 09:48 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 28, 2023 | Option Exercise | $15.31 | 360,000 | 5,511,600 | 945,496 | Aug 30, 2023, 09:48 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 15, 2023 | Option Exercise | $21.51 | 23,304 | 501,269 | 585,496 | Aug 17, 2023, 08:20 PM |
| Senner Christopher J. | EVP and CFO | Aug 15, 2023 | Option Exercise | $21.51 | 8,074 | 173,672 | 563,557 | Aug 17, 2023, 08:19 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Aug 15, 2023 | Option Exercise | $21.51 | 7,177 | 154,377 | 564,799 | Aug 17, 2023, 08:17 PM |
| Haley Patrick J. | EVP, Commercial | Aug 15, 2023 | Option Exercise | $21.51 | 7,177 | 154,377 | 278,290 | Aug 17, 2023, 08:16 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | Aug 15, 2023 | Option Exercise | $21.51 | 6,280 | 135,083 | 404,543 | Aug 17, 2023, 08:14 PM |
| Senner Christopher J. | EVP and CFO | Aug 03, 2023 | Option Exercise | $14.74 | 60,000 | 884,400 | 631,631 | Aug 07, 2023, 09:20 PM |
| Senner Christopher J. | EVP and CFO | Aug 04, 2023 | Option Exercise | $14.74 | 60,000 | 884,400 | 631,631 | Aug 07, 2023, 09:20 PM |
| Senner Christopher J. | EVP and CFO | Aug 04, 2023 | Sale | $20.68 | 60,000 | 1,240,800 | 571,631 | Aug 07, 2023, 09:20 PM |
| Senner Christopher J. | EVP and CFO | Aug 03, 2023 | Sale | $20.51 | 60,000 | 1,230,600 | 571,631 | Aug 07, 2023, 09:20 PM |
| Haley Patrick J. | EVP, Commercial | Aug 03, 2023 | Sale | $20.67 | 30,553 | 631,531 | 285,467 | Aug 07, 2023, 08:24 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Aug 01, 2023 | Option Exercise | $14.74 | 55,710 | 821,165 | 627,686 | Aug 03, 2023, 08:02 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Aug 01, 2023 | Sale | $19.63 | 55,710 | 1,093,587 | 571,976 | Aug 03, 2023, 08:02 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | May 15, 2023 | Option Exercise | $19.18 | 11,967 | 229,527 | 579,003 | May 17, 2023, 08:20 PM |
| Senner Christopher J. | EVP and CFO | May 15, 2023 | Option Exercise | $19.18 | 18,446 | 353,794 | 581,633 | May 17, 2023, 08:16 PM |
| MORRISSEY MICHAEL | President and CEO | May 15, 2023 | Option Exercise | $19.18 | 33,518 | 642,875 | 608,800 | May 17, 2023, 08:14 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | May 15, 2023 | Option Exercise | $19.18 | 10,488 | 201,160 | 416,938 | May 17, 2023, 08:12 PM |
| Haley Patrick J. | EVP, Commercial | May 15, 2023 | Option Exercise | $19.18 | 18,065 | 346,487 | 331,059 | May 17, 2023, 08:09 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Apr 05, 2023 | Option Exercise | $14.74 | 13,930 | 205,328 | 621,365 | Apr 05, 2023, 08:57 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Apr 05, 2023 | Sale | $20.01 | 38,930 | 778,989 | 582,435 | Apr 05, 2023, 08:57 PM |
| WYSZOMIERSKI JACK L | Director | Mar 10, 2023 | Option Exercise | $6.30 | 40,000 | 252,000 | 332,767 | Mar 14, 2023, 08:22 PM |
| WYSZOMIERSKI JACK L | Director | Mar 10, 2023 | Sale | $16.61 | 15,300 | 254,133 | 317,467 | Mar 14, 2023, 08:22 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Mar 01, 2023 | Option Exercise | $14.74 | 27,860 | 410,656 | 605,576 | Mar 03, 2023, 07:59 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Mar 01, 2023 | Sale | $17.13 | 77,860 | 1,333,742 | 527,716 | Mar 03, 2023, 07:59 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | Feb 28, 2023 | Option Exercise | $14.74 | 82,490 | 1,215,903 | 433,962 | Mar 01, 2023, 07:56 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | Feb 27, 2023 | Option Exercise | $14.74 | 10 | 147 | 351,482 | Mar 01, 2023, 07:56 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | Feb 28, 2023 | Sale | $17.50 | 82,490 | 1,443,575 | 351,472 | Mar 01, 2023, 07:56 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | Feb 27, 2023 | Sale | $17.50 | 10 | 175 | 351,472 | Mar 01, 2023, 07:56 PM |
| Garber Alan M | Director | Feb 21, 2023 | Option Exercise | $6.30 | 40,000 | 252,000 | 71,417 | Feb 23, 2023, 09:08 PM |
| Garber Alan M | Director | Feb 21, 2023 | Sale | $17.49 | 40,000 | 699,600 | 31,417 | Feb 23, 2023, 09:08 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 15, 2023 | Option Exercise | $18.08 | 11,522 | 208,318 | 329,133 | Feb 17, 2023, 09:46 PM |
| Haley Patrick J. | EVP, Commercial | Feb 15, 2023 | Option Exercise | $18.08 | 1,556 | 28,132 | 252,858 | Feb 17, 2023, 09:44 PM |
| Senner Christopher J. | EVP and CFO | Feb 15, 2023 | Option Exercise | $18.08 | 5,278 | 95,426 | 504,663 | Feb 17, 2023, 09:42 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Feb 15, 2023 | Option Exercise | $18.08 | 1,929 | 34,876 | 577,716 | Feb 17, 2023, 09:41 PM |
| Aftab Dana | CSO/EVP Disc & Trans Research | Feb 15, 2023 | Option Exercise | $18.08 | 1,529 | 27,644 | 351,472 | Feb 17, 2023, 09:39 PM |
| Goodman Vicki L | EVP, Prod Dev & Med Aff &CMO | Feb 15, 2023 | Option Exercise | $18.08 | 17,299 | 312,766 | 225,088 | Feb 17, 2023, 09:38 PM |
| FELDBAUM CARL B | Director | Feb 09, 2023 | Option Exercise | $6.30 | 40,000 | 252,000 | 58,701 | Feb 10, 2023, 07:56 PM |
| FELDBAUM CARL B | Director | Feb 09, 2023 | Sale | $17.78 | 40,000 | 711,200 | 18,701 | Feb 10, 2023, 07:56 PM |
| Haley Patrick J. | EVP, Commercial | Feb 06, 2023 | Option Exercise | $4.20 | 25,000 | 105,000 | 279,414 | Feb 08, 2023, 08:17 PM |
| Haley Patrick J. | EVP, Commercial | Feb 06, 2023 | Sale | $17.37 | 25,000 | 434,250 | 254,414 | Feb 08, 2023, 08:17 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 24, 2023 | Option Exercise | $17.36 | 62,006 | 1,076,424 | 378,649 | Jan 26, 2023, 08:59 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 24, 2023 | Option Exercise | $4.20 | 100,000 | 420,000 | 440,655 | Jan 26, 2023, 08:59 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Dec 15, 2022 | Option Exercise | $4.20 | 20,000 | 84,000 | 430,958 | Dec 16, 2022, 08:09 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Dec 15, 2022 | Sale | $15.88 | 20,000 | 317,600 | 410,958 | Dec 16, 2022, 08:09 PM |
| POSTE GEORGE | Director | Nov 29, 2022 | Option Exercise | $6.30 | 40,000 | 252,000 | 233,189 | Dec 01, 2022, 08:11 PM |
| POSTE GEORGE | Director | Nov 29, 2022 | Sale | $16.68 | 40,000 | 667,200 | 193,189 | Dec 01, 2022, 08:11 PM |
| Haley Patrick J. | EVP, Commercial | Nov 15, 2022 | Option Exercise | $16.71 | 7,177 | 119,928 | 254,414 | Nov 17, 2022, 08:48 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Nov 15, 2022 | Option Exercise | $16.71 | 7,177 | 119,928 | 579,645 | Nov 17, 2022, 08:46 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | May 16, 2022 | Sale | $20.07 | 18,000 | 361,260 | 586,822 | Nov 17, 2022, 08:46 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | May 17, 2021 | Sale | $25.39 | 18,000 | 457,020 | 604,822 | Nov 17, 2022, 08:46 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Nov 15, 2022 | Option Exercise | $16.71 | 7,177 | 119,928 | 410,958 | Nov 17, 2022, 08:42 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 15, 2022 | Option Exercise | $16.71 | 23,304 | 389,410 | 446,665 | Nov 17, 2022, 08:40 PM |
| Senner Christopher J. | EVP and CFO | Nov 15, 2022 | Option Exercise | $16.71 | 8,074 | 134,917 | 509,941 | Nov 17, 2022, 08:38 PM |
| Haley Patrick J. | EVP, Commercial | Sep 12, 2022 | Option Exercise | $6.21 | 40,000 | 248,400 | 301,591 | Sep 14, 2022, 07:57 PM |
| Haley Patrick J. | EVP, Commercial | Sep 12, 2022 | Sale | $17.94 | 40,000 | 717,600 | 261,591 | Sep 14, 2022, 07:57 PM |
| Senner Christopher J. | EVP and CFO | Aug 11, 2022 | Option Exercise | $19.23 | 152,867 | 2,939,632 | 518,015 | Aug 12, 2022, 08:23 PM |
| Senner Christopher J. | EVP and CFO | Aug 11, 2022 | Option Exercise | $6.21 | 225,000 | 1,397,250 | 670,882 | Aug 12, 2022, 08:23 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 03, 2022 | Option Exercise | $21.49 | 23,304 | 500,803 | 469,969 | Aug 05, 2022, 09:50 PM |
| Senner Christopher J. | EVP and CFO | Aug 03, 2022 | Option Exercise | $21.49 | 8,074 | 173,510 | 445,882 | Aug 05, 2022, 09:48 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Aug 03, 2022 | Option Exercise | $21.49 | 7,177 | 154,234 | 418,135 | Aug 05, 2022, 09:45 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Aug 03, 2022 | Option Exercise | $21.49 | 7,177 | 154,234 | 622,804 | Aug 05, 2022, 09:44 PM |
| Haley Patrick J. | EVP, Commercial | Aug 03, 2022 | Option Exercise | $21.49 | 7,177 | 154,234 | 261,591 | Aug 05, 2022, 09:43 PM |
| Haley Patrick J. | EVP, Commercial | May 27, 2022 | Sale | $18.21 | 18,812 | 342,567 | 239,818 | Jun 01, 2022, 08:28 PM |
| Haley Patrick J. | EVP, Commercial | May 15, 2022 | Option Exercise | $20.08 | 11,723 | 235,398 | 266,014 | May 17, 2022, 08:29 PM |
| Senner Christopher J. | EVP and CFO | May 15, 2022 | Option Exercise | $20.08 | 8,444 | 169,556 | 421,389 | May 17, 2022, 08:23 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | May 15, 2022 | Option Exercise | $20.08 | 6,123 | 122,950 | 396,362 | May 17, 2022, 08:22 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | May 15, 2022 | Option Exercise | $20.08 | 5,349 | 107,408 | 601,031 | May 17, 2022, 08:19 PM |
| WILLSEY LANCE | Director | May 12, 2022 | Option Exercise | $3.13 | 40,000 | 125,200 | 464,415 | May 13, 2022, 08:10 PM |
| WILLSEY LANCE | Director | May 12, 2022 | Sale | $19.65 | 40,000 | 786,000 | 424,415 | May 13, 2022, 08:10 PM |
| WYSZOMIERSKI JACK L | Director | Apr 04, 2022 | Option Exercise | $3.13 | 40,000 | 125,200 | 279,888 | Apr 06, 2022, 08:08 PM |
| WYSZOMIERSKI JACK L | Director | Apr 04, 2022 | Sale | $23.00 | 6,696 | 154,008 | 273,192 | Apr 06, 2022, 08:08 PM |
| Haley Patrick J. | EVP, Commercial | Mar 31, 2022 | Option Exercise | $6.21 | 10,000 | 62,100 | 279,191 | Apr 04, 2022, 08:11 PM |
| Haley Patrick J. | EVP, Commercial | Apr 01, 2022 | Option Exercise | $6.21 | 10,000 | 62,100 | 279,191 | Apr 04, 2022, 08:11 PM |
| Haley Patrick J. | EVP, Commercial | Apr 01, 2022 | Sale | $23.00 | 10,000 | 230,000 | 269,191 | Apr 04, 2022, 08:11 PM |
| Haley Patrick J. | EVP, Commercial | Mar 31, 2022 | Sale | $22.43 | 10,000 | 224,300 | 269,191 | Apr 04, 2022, 08:11 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Mar 29, 2022 | Sale | $22.00 | 13,283 | 292,226 | 605,236 | Mar 30, 2022, 08:17 PM |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | Mar 28, 2022 | Sale | $22.00 | 4,717 | 103,774 | 618,519 | Mar 30, 2022, 08:17 PM |
| Garber Alan M | Director | Mar 01, 2022 | Option Exercise | $3.13 | 40,000 | 125,200 | 52,718 | Mar 03, 2022, 08:07 PM |
| Garber Alan M | Director | Mar 01, 2022 | Sale | $21.00 | 21,301 | 447,321 | 31,417 | Mar 03, 2022, 08:07 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Feb 24, 2022 | Sale | $20.00 | 18,000 | 360,000 | 555,361 | Feb 28, 2022, 08:11 PM |
| Haley Patrick J. | EVP, Commercial | Feb 25, 2022 | Sale | $19.53 | 31,238 | 610,078 | 198,476 | Feb 28, 2022, 08:09 PM |
| PAPADOPOULOS STELIOS | Director | Feb 22, 2022 | Sale | $19.56 | 84,515 | 1,653,113 | 1,220,036 | Feb 24, 2022, 08:22 PM |
| FELDBAUM CARL B | Director | Feb 22, 2022 | Option Exercise | $3.13 | 20,000 | 62,600 | 28,521 | Feb 24, 2022, 08:20 PM |
| FELDBAUM CARL B | Director | Feb 22, 2022 | Sale | $19.49 | 20,000 | 389,800 | 8,521 | Feb 24, 2022, 08:20 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Feb 15, 2022 | Option Exercise | $18.59 | 20,177 | 375,090 | 360,646 | Feb 17, 2022, 08:09 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Feb 15, 2022 | Option Exercise | $18.59 | 12,226 | 227,281 | 584,570 | Feb 17, 2022, 08:07 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 15, 2022 | Option Exercise | $18.59 | 65,147 | 1,211,083 | 187,900 | Feb 17, 2022, 08:06 PM |
| Senner Christopher J. | EVP and CFO | Feb 15, 2022 | Option Exercise | $18.59 | 18,327 | 340,699 | 369,474 | Feb 17, 2022, 08:04 PM |
| Haley Patrick J. | EVP, Commercial | Feb 15, 2022 | Option Exercise | $18.59 | 15,527 | 288,647 | 244,443 | Feb 17, 2022, 07:59 PM |
| Haley Patrick J. | EVP, Commercial | Feb 03, 2022 | Option Exercise | $1.90 | 60,000 | 114,000 | 305,241 | Feb 04, 2022, 09:52 PM |
| Haley Patrick J. | EVP, Commercial | Feb 03, 2022 | Sale | $17.91 | 60,000 | 1,074,600 | 245,241 | Feb 04, 2022, 09:52 PM |
| Goodman Vicki L | EVP, Prod Dev & Med Aff &CMO | Jan 04, 2022 | Option Exercise | $19.18 | 7,613 | 146,017 | 242,387 | Jan 06, 2022, 08:02 PM |
| MORRISSEY MICHAEL | President and CEO | Dec 15, 2021 | Option Exercise | $17.00 | 12,236 | 208,012 | 205,006 | Dec 17, 2021, 08:41 PM |
| Haley Patrick J. | EVP, Commercial | Dec 15, 2021 | Option Exercise | $17.00 | 1,556 | 26,452 | 245,241 | Dec 17, 2021, 08:38 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Dec 15, 2021 | Option Exercise | $17.00 | 4,646 | 78,982 | 363,172 | Dec 17, 2021, 08:35 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Dec 15, 2021 | Option Exercise | $6.21 | 47,500 | 294,975 | 410,672 | Dec 17, 2021, 08:35 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Dec 15, 2021 | Sale | $17.44 | 47,500 | 828,400 | 363,172 | Dec 17, 2021, 08:35 PM |
| Senner Christopher J. | EVP and CFO | Dec 15, 2021 | Option Exercise | $17.00 | 5,131 | 87,227 | 372,175 | Dec 17, 2021, 08:32 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Dec 15, 2021 | Option Exercise | $17.00 | 2,621 | 44,557 | 585,587 | Dec 17, 2021, 08:26 PM |
| Haley Patrick J. | EVP, Commercial | Nov 24, 2021 | Sale | $17.25 | 17,236 | 297,321 | 237,802 | Nov 26, 2021, 07:39 PM |
| FELDBAUM CARL B | Director | Nov 19, 2021 | Option Exercise | $3.13 | 20,000 | 62,600 | 28,521 | Nov 23, 2021, 08:11 PM |
| FELDBAUM CARL B | Director | Nov 19, 2021 | Sale | $17.62 | 20,000 | 352,400 | 8,521 | Nov 23, 2021, 08:11 PM |
| Haley Patrick J. | EVP, Commercial | Nov 15, 2021 | Option Exercise | $18.10 | 49,490 | 895,769 | 300,205 | Nov 17, 2021, 08:40 PM |
| Senner Christopher J. | EVP and CFO | Nov 15, 2021 | Option Exercise | $18.10 | 57,713 | 1,044,605 | 407,301 | Nov 17, 2021, 08:39 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Nov 15, 2021 | Option Exercise | $18.10 | 54,611 | 988,459 | 626,268 | Nov 17, 2021, 08:37 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 15, 2021 | Option Exercise | $18.10 | 193,780 | 3,507,418 | 550,538 | Nov 17, 2021, 08:33 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Nov 15, 2021 | Option Exercise | $18.10 | 62,163 | 1,125,150 | 404,422 | Nov 17, 2021, 08:02 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Nov 15, 2021 | Option Exercise | $6.21 | 47,500 | 294,975 | 458,740 | Nov 17, 2021, 08:02 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Nov 15, 2021 | Sale | $18.09 | 47,500 | 859,275 | 411,240 | Nov 17, 2021, 08:02 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Nov 01, 2021 | Sale | $22.03 | 5,117 | 112,728 | 632,825 | Nov 03, 2021, 08:12 PM |
| MORRISSEY MICHAEL | President and CEO | Oct 22, 2021 | Option Exercise | $21.33 | 24,747 | 527,854 | 561,068 | Oct 22, 2021, 08:19 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Oct 15, 2021 | Option Exercise | $6.21 | 47,500 | 294,975 | 458,740 | Oct 15, 2021, 08:15 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Oct 15, 2021 | Sale | $21.92 | 47,500 | 1,041,200 | 411,240 | Oct 15, 2021, 08:15 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Oct 15, 2021 | Sale | $22.02 | 12,883 | 283,684 | 637,942 | Oct 15, 2021, 08:14 PM |
| Senner Christopher J. | EVP and CFO | Sep 30, 2021 | Option Exercise | $20.63 | 8,573 | 176,861 | 415,528 | Oct 04, 2021, 08:13 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 30, 2021 | Option Exercise | $20.63 | 7,593 | 156,644 | 650,825 | Oct 04, 2021, 08:12 PM |
| Haley Patrick J. | EVP, Commercial | Sep 30, 2021 | Option Exercise | $20.63 | 5,416 | 111,732 | 304,528 | Oct 04, 2021, 08:08 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Sep 30, 2021 | Option Exercise | $20.63 | 7,177 | 148,062 | 411,240 | Oct 04, 2021, 08:02 PM |
| Senner Christopher J. | EVP and CFO | Sep 21, 2021 | Option Exercise | $20.33 | 55,057 | 1,119,309 | 391,534 | Sep 23, 2021, 08:16 PM |
| Senner Christopher J. | EVP and CFO | Sep 21, 2021 | Option Exercise | $3.66 | 90,000 | 329,400 | 446,591 | Sep 23, 2021, 08:16 PM |
| Haley Patrick J. | EVP, Commercial | Sep 16, 2021 | Option Exercise | $1.70 | 25,000 | 42,500 | 305,994 | Sep 17, 2021, 07:58 PM |
| Haley Patrick J. | EVP, Commercial | Sep 16, 2021 | Sale | $20.36 | 25,000 | 509,000 | 280,994 | Sep 17, 2021, 07:58 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Sep 15, 2021 | Option Exercise | $6.21 | 47,500 | 294,975 | 436,967 | Sep 17, 2021, 07:56 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Sep 15, 2021 | Sale | $20.46 | 47,500 | 971,850 | 389,467 | Sep 17, 2021, 07:56 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Aug 16, 2021 | Option Exercise | $1.90 | 55,000 | 104,500 | 444,467 | Aug 18, 2021, 07:56 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Aug 16, 2021 | Sale | $18.44 | 55,000 | 1,014,200 | 389,467 | Aug 18, 2021, 07:56 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Jul 26, 2021 | Option Exercise | $4.20 | 40,000 | 168,000 | 689,078 | Jul 28, 2021, 08:06 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Jul 21, 2021 | Option Exercise | $4.20 | 35,000 | 147,000 | 649,078 | Jul 23, 2021, 07:47 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jul 15, 2021 | Option Exercise | $1.90 | 60,000 | 114,000 | 449,467 | Jul 16, 2021, 07:58 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jul 15, 2021 | Sale | $17.47 | 60,000 | 1,048,200 | 389,467 | Jul 16, 2021, 07:58 PM |
| COHEN CHARLES | Director | Jul 06, 2021 | Option Exercise | $4.72 | 80,000 | 377,200 | 261,375 | Jul 08, 2021, 07:45 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 17, 2021 | Option Exercise | $1.90 | 60,000 | 114,000 | 449,467 | Jun 22, 2021, 08:03 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 17, 2021 | Sale | $22.18 | 60,000 | 1,330,800 | 389,467 | Jun 22, 2021, 08:03 PM |
| Freire Maria C | Director | May 11, 2021 | Sale | $25.01 | 8,275 | 206,958 | 31,827 | May 17, 2021, 08:15 PM |
| POSTE GEORGE | Director | May 14, 2021 | Sale | $24.97 | 40,802 | 1,018,826 | 157,190 | May 17, 2021, 08:11 PM |
| MORRISSEY MICHAEL | President and CEO | May 12, 2021 | Option Exercise | $25.16 | 30,278 | 761,794 | 511,535 | May 14, 2021, 08:51 PM |
| MORRISSEY MICHAEL | President and CEO | May 12, 2021 | Option Exercise | $4.20 | 50,000 | 210,000 | 541,813 | May 14, 2021, 08:51 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | May 13, 2021 | Option Exercise | $1.90 | 100,000 | 190,000 | 714,078 | May 14, 2021, 08:35 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | May 13, 2021 | Sale | $25.38 | 100,000 | 2,538,000 | 614,078 | May 14, 2021, 08:35 PM |
| PAPADOPOULOS STELIOS | Director | May 11, 2021 | Option Exercise | $4.27 | 120,000 | 512,400 | 1,293,600 | May 13, 2021, 08:32 PM |
| PAPADOPOULOS STELIOS | Director | May 11, 2021 | Sale | $24.98 | 20,770 | 518,794 | 1,288,127 | May 13, 2021, 08:32 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Apr 26, 2021 | Option Exercise | $1.70 | 50,000 | 85,000 | 663,482 | Apr 28, 2021, 08:10 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Apr 26, 2021 | Sale | $25.00 | 50,000 | 1,250,000 | 613,482 | Apr 28, 2021, 08:10 PM |
| Haley Patrick J. | EVP, Commercial | Apr 26, 2021 | Sale | $25.03 | 7,665 | 191,855 | 297,392 | Apr 28, 2021, 08:08 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Apr 26, 2021 | Sale | $25.03 | 18,000 | 450,540 | 628,248 | Apr 28, 2021, 08:06 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Apr 01, 2021 | Option Exercise | $1.70 | 60,000 | 102,000 | 449,467 | Apr 02, 2021, 07:51 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Apr 01, 2021 | Sale | $22.96 | 60,000 | 1,377,600 | 389,467 | Apr 02, 2021, 07:51 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Apr 01, 2021 | Option Exercise | $1.70 | 50,000 | 85,000 | 663,482 | Apr 02, 2021, 07:41 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Apr 01, 2021 | Sale | $23.00 | 50,000 | 1,150,000 | 613,482 | Apr 02, 2021, 07:41 PM |
| WYSZOMIERSKI JACK L | Director | Mar 29, 2021 | Option Exercise | $3.38 | 40,000 | 135,200 | 237,809 | Mar 31, 2021, 09:02 PM |
| WYSZOMIERSKI JACK L | Director | Mar 29, 2021 | Sale | $22.64 | 6,220 | 140,821 | 231,589 | Mar 31, 2021, 09:02 PM |
| Garber Alan M | Director | Mar 15, 2021 | Option Exercise | $3.38 | 40,000 | 135,200 | 52,718 | Mar 17, 2021, 08:11 PM |
| Garber Alan M | Director | Mar 15, 2021 | Sale | $23.60 | 40,000 | 944,000 | 12,718 | Mar 17, 2021, 08:11 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Mar 01, 2021 | Option Exercise | $1.70 | 65,000 | 110,500 | 405,072 | Mar 03, 2021, 07:49 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Mar 01, 2021 | Sale | $22.11 | 65,000 | 1,437,150 | 340,072 | Mar 03, 2021, 07:49 PM |
| COHEN CHARLES | Director | Feb 24, 2021 | Option Exercise | $3.38 | 40,000 | 135,200 | 221,375 | Feb 26, 2021, 08:10 PM |
| COHEN CHARLES | Director | Feb 24, 2021 | Sale | $22.69 | 40,000 | 907,600 | 181,375 | Feb 26, 2021, 08:10 PM |
| POSTE GEORGE | Director | Feb 22, 2021 | Option Exercise | $3.38 | 40,000 | 135,200 | 197,992 | Feb 24, 2021, 08:18 PM |
| MARCHESI VINCENT T | Director | Feb 22, 2021 | Sale | $22.29 | 24,097 | 537,122 | 66,115 | Feb 24, 2021, 08:15 PM |
| WILLSEY LANCE | Director | Feb 23, 2021 | Option Exercise | $3.38 | 40,000 | 135,200 | 464,415 | Feb 24, 2021, 08:11 PM |
| WILLSEY LANCE | Director | Feb 23, 2021 | Sale | $21.93 | 40,000 | 877,136 | 425,215 | Feb 24, 2021, 08:11 PM |
| WILLSEY LANCE | Director | Feb 16, 2021 | Sale | $21.90 | 50,000 | 1,095,000 | 424,415 | Feb 24, 2021, 08:11 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 17, 2021 | Option Exercise | $1.70 | 50,000 | 85,000 | 590,597 | Feb 19, 2021, 07:57 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 18, 2021 | Option Exercise | $1.70 | 50,000 | 85,000 | 590,597 | Feb 19, 2021, 07:57 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 18, 2021 | Sale | $22.35 | 50,000 | 1,117,500 | 540,597 | Feb 19, 2021, 07:57 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 17, 2021 | Sale | $22.50 | 50,000 | 1,125,000 | 540,597 | Feb 19, 2021, 07:57 PM |
| Haley Patrick J. | EVP, Commercial | Feb 15, 2021 | Option Exercise | $21.91 | 1,400 | 30,674 | 245,487 | Feb 17, 2021, 08:15 PM |
| Haley Patrick J. | EVP, Commercial | Feb 12, 2021 | Sale | $21.57 | 45,000 | 970,650 | 246,887 | Feb 17, 2021, 08:15 PM |
| Senner Christopher J. | EVP and CFO | Feb 15, 2021 | Option Exercise | $21.91 | 4,105 | 89,941 | 292,441 | Feb 17, 2021, 08:13 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Feb 15, 2021 | Option Exercise | $21.91 | 1,685 | 36,918 | 589,113 | Feb 17, 2021, 08:11 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 15, 2021 | Option Exercise | $21.91 | 2,858 | 62,619 | 540,597 | Feb 17, 2021, 08:10 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 15, 2021 | Option Exercise | $21.91 | 9,789 | 214,477 | 559,187 | Feb 17, 2021, 08:07 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Feb 15, 2021 | Option Exercise | $21.91 | 3,718 | 81,461 | 340,072 | Feb 17, 2021, 08:05 PM |
| FELDBAUM CARL B | Director | Feb 16, 2021 | Option Exercise | $3.38 | 20,000 | 67,600 | 28,521 | Feb 17, 2021, 08:03 PM |
| FELDBAUM CARL B | Director | Feb 16, 2021 | Sale | $21.96 | 20,000 | 439,200 | 8,521 | Feb 17, 2021, 08:03 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 03, 2021 | Option Exercise | $22.56 | 65,190 | 1,470,686 | 568,976 | Feb 05, 2021, 09:53 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Feb 03, 2021 | Option Exercise | $22.56 | 19,997 | 451,132 | 343,790 | Feb 05, 2021, 09:18 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Feb 03, 2021 | Option Exercise | $22.56 | 15,365 | 346,634 | 590,798 | Feb 05, 2021, 09:16 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 03, 2021 | Option Exercise | $22.56 | 14,982 | 337,994 | 543,455 | Feb 05, 2021, 09:16 PM |
| Haley Patrick J. | EVP, Commercial | Feb 03, 2021 | Option Exercise | $22.56 | 11,267 | 254,184 | 291,887 | Feb 05, 2021, 09:15 PM |
| Senner Christopher J. | EVP and CFO | Feb 03, 2021 | Option Exercise | $22.56 | 18,206 | 410,727 | 296,546 | Feb 05, 2021, 09:14 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Feb 01, 2021 | Option Exercise | $1.70 | 65,000 | 110,500 | 348,124 | Feb 03, 2021, 07:57 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Feb 01, 2021 | Sale | $22.08 | 65,000 | 1,435,200 | 283,124 | Feb 03, 2021, 07:57 PM |
| Senner Christopher J. | EVP and CFO | Jan 12, 2021 | Option Exercise | $3.66 | 30,000 | 109,800 | 275,596 | Jan 14, 2021, 08:22 PM |
| Senner Christopher J. | EVP and CFO | Jan 12, 2021 | Sale | $25.00 | 30,000 | 750,000 | 245,596 | Jan 14, 2021, 08:22 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jan 04, 2021 | Option Exercise | $1.70 | 65,000 | 110,500 | 348,124 | Jan 06, 2021, 08:40 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jan 04, 2021 | Sale | $20.32 | 65,000 | 1,320,800 | 283,124 | Jan 06, 2021, 08:40 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Jan 04, 2021 | Option Exercise | $5.12 | 50,000 | 256,100 | 541,754 | Jan 06, 2021, 08:22 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Dec 18, 2020 | Option Exercise | $1.70 | 65,000 | 110,500 | 348,124 | Dec 22, 2020, 07:58 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Dec 18, 2020 | Sale | $20.01 | 65,000 | 1,300,650 | 283,124 | Dec 22, 2020, 07:58 PM |
| WILLSEY LANCE | Director | Dec 04, 2020 | Option Exercise | $5.82 | 106,142 | 617,746 | 474,415 | Dec 04, 2020, 07:56 PM |
| MARCHESI VINCENT T | Director | Nov 24, 2020 | Option Exercise | $5.82 | 40,004 | 232,823 | 130,216 | Nov 25, 2020, 07:46 PM |
| MARCHESI VINCENT T | Director | Nov 24, 2020 | Sale | $18.50 | 40,004 | 740,074 | 90,212 | Nov 25, 2020, 07:46 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 15, 2020 | Option Exercise | $20.16 | 24,954 | 503,073 | 592,308 | Nov 17, 2020, 08:11 PM |
| Haley Patrick J. | EVP, Commercial | Nov 15, 2020 | Option Exercise | $20.16 | 10,446 | 210,591 | 248,352 | Nov 17, 2020, 08:09 PM |
| Senner Christopher J. | EVP and CFO | Nov 15, 2020 | Option Exercise | $20.16 | 13,597 | 274,116 | 256,456 | Nov 17, 2020, 08:07 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Nov 15, 2020 | Option Exercise | $20.16 | 11,311 | 228,030 | 291,956 | Nov 17, 2020, 08:06 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Nov 15, 2020 | Option Exercise | $20.16 | 10,261 | 206,862 | 472,942 | Nov 17, 2020, 08:00 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Nov 15, 2020 | Option Exercise | $7.27 | 30,000 | 218,100 | 494,254 | Nov 17, 2020, 08:00 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Nov 15, 2020 | Option Exercise | $20.16 | 14,953 | 301,452 | 489,667 | Nov 17, 2020, 07:57 PM |
| WYSZOMIERSKI JACK L | Director | Nov 10, 2020 | Option Exercise | $5.82 | 62,403 | 363,185 | 231,809 | Nov 13, 2020, 08:18 PM |
| WYSZOMIERSKI JACK L | Director | Nov 10, 2020 | Sale | $20.61 | 34,000 | 700,740 | 197,809 | Nov 13, 2020, 08:18 PM |
| MORRISSEY MICHAEL | President and CEO | Oct 22, 2020 | Option Exercise | $21.79 | 177,132 | 3,859,706 | 598,834 | Oct 26, 2020, 08:12 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Oct 22, 2020 | Option Exercise | $21.79 | 55,235 | 1,203,571 | 491,835 | Oct 26, 2020, 08:11 PM |
| Haley Patrick J. | EVP, Commercial | Oct 22, 2020 | Option Exercise | $21.79 | 44,184 | 962,769 | 249,618 | Oct 26, 2020, 08:07 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Oct 22, 2020 | Option Exercise | $21.79 | 46,742 | 1,018,508 | 474,515 | Oct 26, 2020, 08:04 PM |
| Senner Christopher J. | EVP and CFO | Oct 22, 2020 | Option Exercise | $21.79 | 46,920 | 1,022,387 | 259,193 | Oct 26, 2020, 08:00 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Oct 22, 2020 | Option Exercise | $21.79 | 53,022 | 1,155,349 | 294,435 | Oct 26, 2020, 07:57 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Oct 21, 2020 | Option Exercise | $7.27 | 39,742 | 288,924 | 382,768 | Oct 23, 2020, 08:08 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Oct 21, 2020 | Sale | $21.95 | 39,742 | 872,337 | 343,026 | Oct 23, 2020, 08:08 PM |
| Senner Christopher J. | EVP and CFO | Oct 08, 2020 | Option Exercise | $3.66 | 10,000 | 36,600 | 137,882 | Oct 09, 2020, 08:04 PM |
| Senner Christopher J. | EVP and CFO | Oct 08, 2020 | Sale | $25.00 | 10,000 | 250,000 | 127,882 | Oct 09, 2020, 08:04 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 22, 2020 | Option Exercise | $7.27 | 10,258 | 74,576 | 353,284 | Sep 24, 2020, 08:03 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 22, 2020 | Sale | $26.14 | 10,258 | 268,144 | 343,026 | Sep 24, 2020, 08:03 PM |
| Haley Patrick J. | EVP, Commercial | Sep 21, 2020 | Option Exercise | $5.82 | 4,680 | 27,238 | 120,251 | Sep 23, 2020, 08:12 PM |
| Haley Patrick J. | EVP, Commercial | Sep 21, 2020 | Sale | $26.09 | 4,680 | 122,101 | 115,571 | Sep 23, 2020, 08:12 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 16, 2020 | Option Exercise | $7.27 | 20,000 | 145,400 | 363,026 | Sep 16, 2020, 08:24 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 16, 2020 | Sale | $26.11 | 20,000 | 522,200 | 343,026 | Sep 16, 2020, 08:24 PM |
| Senner Christopher J. | EVP and CFO | Sep 15, 2020 | Option Exercise | $3.66 | 20,000 | 73,200 | 147,882 | Sep 15, 2020, 08:03 PM |
| Senner Christopher J. | EVP and CFO | Sep 15, 2020 | Sale | $25.00 | 20,000 | 500,000 | 127,882 | Sep 15, 2020, 08:03 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 08, 2020 | Option Exercise | $20.71 | 160,666 | 3,327,393 | 343,026 | Sep 10, 2020, 08:39 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 08, 2020 | Option Exercise | $5.18 | 249,692 | 1,293,315 | 503,692 | Sep 10, 2020, 08:39 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Sep 02, 2020 | Option Exercise | $21.58 | 2,323 | 50,130 | 133,578 | Sep 04, 2020, 06:41 PM |
| Haley Patrick J. | EVP, Commercial | Sep 02, 2020 | Option Exercise | $21.58 | 1,116 | 24,083 | 115,571 | Sep 04, 2020, 06:40 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 02, 2020 | Option Exercise | $21.58 | 1,311 | 28,291 | 254,000 | Sep 04, 2020, 06:38 PM |
| Senner Christopher J. | EVP and CFO | Sep 02, 2020 | Option Exercise | $21.58 | 2,566 | 55,374 | 127,882 | Sep 04, 2020, 06:36 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Sep 02, 2020 | Option Exercise | $21.58 | 2,517 | 54,317 | 333,191 | Sep 04, 2020, 06:32 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 02, 2020 | Option Exercise | $21.58 | 6,118 | 132,026 | 103,105 | Sep 04, 2020, 06:31 PM |
| COHEN CHARLES | Director | Sep 01, 2020 | Option Exercise | $5.82 | 115,396 | 671,605 | 181,375 | Sep 03, 2020, 08:05 PM |
| POSTE GEORGE | Director | Aug 14, 2020 | Option Exercise | $5.82 | 29,662 | 172,633 | 157,992 | Aug 14, 2020, 07:50 PM |
| MORRISSEY MICHAEL | President and CEO | Jul 20, 2020 | Option Exercise | $25.60 | 64,137 | 1,641,907 | 121,848 | Jul 22, 2020, 07:06 PM |
| MORRISSEY MICHAEL | President and CEO | Jul 20, 2020 | Option Exercise | $6.21 | 100,000 | 621,000 | 185,985 | Jul 22, 2020, 07:06 PM |
| Haley Patrick J. | EVP, Commercial | Jul 20, 2020 | Sale | $25.36 | 3,151 | 79,909 | 112,189 | Jul 22, 2020, 07:01 PM |
| MORRISSEY MICHAEL | President and CEO | Jul 10, 2020 | Option Exercise | $24.94 | 64,441 | 1,607,159 | 121,544 | Jul 10, 2020, 08:48 PM |
| MORRISSEY MICHAEL | President and CEO | Jul 10, 2020 | Option Exercise | $6.21 | 100,000 | 621,000 | 185,985 | Jul 10, 2020, 08:48 PM |
| MORRISSEY MICHAEL | President and CEO | Jun 19, 2020 | Option Exercise | $24.18 | 64,811 | 1,567,130 | 121,174 | Jun 19, 2020, 09:20 PM |
| MORRISSEY MICHAEL | President and CEO | Jun 19, 2020 | Option Exercise | $6.21 | 100,000 | 621,000 | 185,985 | Jun 19, 2020, 09:20 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 08, 2020 | Option Exercise | $5.51 | 26,000 | 143,260 | 152,531 | Jun 10, 2020, 08:19 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 08, 2020 | Sale | $22.56 | 26,000 | 586,560 | 126,531 | Jun 10, 2020, 08:19 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Jun 04, 2020 | Option Exercise | $1.70 | 100,000 | 170,000 | 425,963 | Jun 05, 2020, 08:00 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Jun 04, 2020 | Sale | $22.96 | 100,000 | 2,296,000 | 325,963 | Jun 05, 2020, 08:00 PM |
| MORRISSEY MICHAEL | President and CEO | May 29, 2020 | Option Exercise | $24.71 | 64,550 | 1,595,030 | 121,435 | May 29, 2020, 09:36 PM |
| MORRISSEY MICHAEL | President and CEO | May 29, 2020 | Option Exercise | $6.21 | 100,000 | 621,000 | 185,985 | May 29, 2020, 09:36 PM |
| MARCHESI VINCENT T | Director | May 21, 2020 | Option Exercise | $5.82 | 40,000 | 232,800 | 130,212 | May 22, 2020, 09:11 PM |
| MARCHESI VINCENT T | Director | May 21, 2020 | Sale | $24.64 | 40,000 | 985,600 | 90,212 | May 22, 2020, 09:11 PM |
| Garber Alan M | Director | May 22, 2020 | Sale | $24.42 | 36,111 | 881,831 | 12,718 | May 22, 2020, 08:53 PM |
| Haley Patrick J. | EVP, Commercial | May 20, 2020 | Sale | $24.99 | 3,151 | 78,743 | 115,340 | May 22, 2020, 08:17 PM |
| WILLSEY LANCE | Director | May 18, 2020 | Option Exercise | $4.58 | 30,000 | 137,400 | 398,273 | May 20, 2020, 08:36 PM |
| WILLSEY LANCE | Director | May 18, 2020 | Sale | $26.26 | 30,000 | 787,800 | 368,273 | May 20, 2020, 08:36 PM |
| SCANGOS GEORGE A | Director | May 18, 2020 | Sale | $25.96 | 75,000 | 1,947,000 | 714,717 | May 20, 2020, 08:35 PM |
| MORRISSEY MICHAEL | President and CEO | May 15, 2020 | Option Exercise | $25.76 | 64,065 | 1,650,314 | 121,920 | May 15, 2020, 09:29 PM |
| MORRISSEY MICHAEL | President and CEO | May 15, 2020 | Option Exercise | $6.21 | 100,000 | 621,000 | 185,985 | May 15, 2020, 09:29 PM |
| SCANGOS GEORGE A | Director | May 15, 2020 | Option Exercise | $5.10 | 51,686 | 263,613 | 789,717 | May 15, 2020, 08:31 PM |
| Hessekiel Jeffrey | EVP and General Counsel | May 13, 2020 | Option Exercise | $26.53 | 13,875 | 368,104 | 250,313 | May 15, 2020, 08:20 PM |
| Hessekiel Jeffrey | EVP and General Counsel | May 13, 2020 | Option Exercise | $1.70 | 25,000 | 42,500 | 264,188 | May 15, 2020, 08:20 PM |
| WILLSEY LANCE | Director | May 14, 2020 | Option Exercise | $5.92 | 15,000 | 88,800 | 383,273 | May 15, 2020, 08:19 PM |
| WILLSEY LANCE | Director | May 14, 2020 | Sale | $25.26 | 15,000 | 378,900 | 368,273 | May 15, 2020, 08:19 PM |
| PAPADOPOULOS STELIOS | Director | May 13, 2020 | Option Exercise | $5.82 | 120,791 | 703,004 | 1,173,359 | May 15, 2020, 08:18 PM |
| MARCHESI VINCENT T | Director | May 11, 2020 | Option Exercise | $4.58 | 30,000 | 137,400 | 112,484 | May 13, 2020, 09:16 PM |
| MARCHESI VINCENT T | Director | May 11, 2020 | Sale | $26.30 | 30,000 | 789,000 | 82,484 | May 13, 2020, 09:16 PM |
| Hessekiel Jeffrey | EVP and General Counsel | May 08, 2020 | Option Exercise | $1.90 | 25,000 | 47,500 | 264,188 | May 11, 2020, 08:36 PM |
| Hessekiel Jeffrey | EVP and General Counsel | May 07, 2020 | Option Exercise | $1.90 | 30,000 | 57,000 | 269,188 | May 11, 2020, 08:36 PM |
| Hessekiel Jeffrey | EVP and General Counsel | May 11, 2020 | Option Exercise | $1.90 | 38,006 | 72,211 | 277,194 | May 11, 2020, 08:36 PM |
| Hessekiel Jeffrey | EVP and General Counsel | May 07, 2020 | Sale | $25.61 | 30,000 | 768,300 | 239,188 | May 11, 2020, 08:36 PM |
| Hessekiel Jeffrey | EVP and General Counsel | May 11, 2020 | Sale | $27.09 | 38,006 | 1,029,583 | 239,188 | May 11, 2020, 08:36 PM |
| Hessekiel Jeffrey | EVP and General Counsel | May 08, 2020 | Sale | $26.04 | 25,000 | 651,000 | 239,188 | May 11, 2020, 08:36 PM |
| Senner Christopher J. | EVP and CFO | May 07, 2020 | Option Exercise | $3.66 | 21,417 | 78,386 | 142,120 | May 08, 2020, 09:22 PM |
| Senner Christopher J. | EVP and CFO | May 08, 2020 | Option Exercise | $3.66 | 78,583 | 287,614 | 199,286 | May 08, 2020, 09:22 PM |
| Senner Christopher J. | EVP and CFO | May 08, 2020 | Sale | $25.81 | 78,583 | 2,028,227 | 120,703 | May 08, 2020, 09:22 PM |
| Senner Christopher J. | EVP and CFO | May 07, 2020 | Sale | $25.80 | 21,417 | 552,559 | 120,703 | May 08, 2020, 09:22 PM |
| PAPADOPOULOS STELIOS | Director | May 08, 2020 | Option Exercise | $5.03 | 45,000 | 226,200 | 1,097,568 | May 08, 2020, 09:18 PM |
| PAPADOPOULOS STELIOS | Director | May 08, 2020 | Sale | $25.84 | 45,000 | 1,162,800 | 1,052,568 | May 08, 2020, 09:18 PM |
| Haley Patrick J. | EVP, Commercial | May 08, 2020 | Option Exercise | $1.76 | 21,375 | 37,620 | 139,866 | May 08, 2020, 09:16 PM |
| Haley Patrick J. | EVP, Commercial | May 08, 2020 | Sale | $25.87 | 21,375 | 552,971 | 118,491 | May 08, 2020, 09:16 PM |
| FELDBAUM CARL B | Director | May 07, 2020 | Option Exercise | $4.27 | 31,546 | 134,798 | 40,067 | May 08, 2020, 09:14 PM |
| FELDBAUM CARL B | Director | May 07, 2020 | Sale | $25.02 | 31,546 | 789,281 | 8,521 | May 08, 2020, 09:14 PM |
| POSTE GEORGE | Director | May 07, 2020 | Option Exercise | $5.82 | 30,000 | 174,600 | 142,792 | May 08, 2020, 09:13 PM |
| POSTE GEORGE | Director | May 07, 2020 | Sale | $25.61 | 30,000 | 768,300 | 112,792 | May 08, 2020, 09:13 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | May 07, 2020 | Option Exercise | $5.51 | 50,000 | 275,500 | 176,531 | May 08, 2020, 09:11 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | May 07, 2020 | Sale | $25.54 | 50,000 | 1,277,000 | 126,531 | May 08, 2020, 09:11 PM |
| MORRISSEY MICHAEL | President and CEO | May 06, 2020 | Option Exercise | $26.19 | 158,971 | 4,163,451 | 212,298 | May 08, 2020, 09:10 PM |
| MORRISSEY MICHAEL | President and CEO | May 06, 2020 | Option Exercise | $1.70 | 285,284 | 484,983 | 371,269 | May 08, 2020, 09:10 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 27, 2020 | Option Exercise | $27.37 | 158,435 | 4,336,366 | 212,550 | Apr 29, 2020, 08:10 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 27, 2020 | Option Exercise | $1.70 | 285,000 | 484,500 | 370,985 | Apr 29, 2020, 08:10 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 23, 2020 | Option Exercise | $26.37 | 156,360 | 4,123,213 | 179,625 | Apr 24, 2020, 08:41 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 23, 2020 | Option Exercise | $5.51 | 250,000 | 1,377,500 | 335,985 | Apr 24, 2020, 08:41 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Apr 23, 2020 | Option Exercise | $1.70 | 100,000 | 170,000 | 425,122 | Apr 24, 2020, 08:25 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Apr 23, 2020 | Sale | $26.00 | 100,000 | 2,600,000 | 325,122 | Apr 24, 2020, 08:25 PM |
| SCANGOS GEORGE A | Director | Apr 24, 2020 | Sale | $26.24 | 15,000 | 393,600 | 738,031 | Apr 24, 2020, 08:24 PM |
| SCANGOS GEORGE A | Director | Apr 23, 2020 | Sale | $25.99 | 100,000 | 2,598,635 | 808,731 | Apr 24, 2020, 08:24 PM |
| Haley Patrick J. | EVP, Commercial | Apr 23, 2020 | Option Exercise | $1.70 | 5,000 | 8,500 | 121,873 | Apr 24, 2020, 08:22 PM |
| Haley Patrick J. | EVP, Commercial | Apr 23, 2020 | Sale | $26.00 | 5,000 | 130,000 | 116,873 | Apr 24, 2020, 08:22 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 21, 2020 | Option Exercise | $24.56 | 139,201 | 3,418,776 | 253,863 | Apr 22, 2020, 09:53 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 20, 2020 | Option Exercise | $23.58 | 152,921 | 3,605,877 | 173,064 | Apr 22, 2020, 09:53 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 20, 2020 | Option Exercise | $5.51 | 240,000 | 1,322,400 | 325,985 | Apr 22, 2020, 09:53 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 21, 2020 | Option Exercise | $5.51 | 220,000 | 1,212,200 | 393,064 | Apr 22, 2020, 09:53 PM |
| SCANGOS GEORGE A | Director | Apr 22, 2020 | Sale | $25.05 | 4,200 | 105,210 | 853,031 | Apr 22, 2020, 08:50 PM |
| SCANGOS GEORGE A | Director | Apr 21, 2020 | Sale | $25.04 | 5,800 | 145,232 | 857,231 | Apr 22, 2020, 08:50 PM |
| SCANGOS GEORGE A | Director | Apr 20, 2020 | Sale | $23.89 | 50,000 | 1,194,637 | 894,531 | Apr 22, 2020, 08:50 PM |
| Haley Patrick J. | EVP, Commercial | Apr 20, 2020 | Option Exercise | $1.70 | 5,000 | 8,500 | 121,873 | Apr 22, 2020, 08:49 PM |
| Haley Patrick J. | EVP, Commercial | Apr 20, 2020 | Sale | $24.00 | 5,000 | 120,000 | 116,873 | Apr 22, 2020, 08:49 PM |
| SCANGOS GEORGE A | Director | Apr 15, 2020 | Sale | $18.31 | 25,000 | 457,750 | 913,031 | Apr 17, 2020, 08:11 PM |
| SCANGOS GEORGE A | Director | Apr 08, 2020 | Sale | $18.35 | 7,065 | 129,643 | 938,031 | Apr 09, 2020, 08:20 PM |
| SCANGOS GEORGE A | Director | Apr 07, 2020 | Sale | $18.25 | 16,435 | 299,939 | 945,096 | Apr 09, 2020, 08:20 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Apr 06, 2020 | Option Exercise | $5.51 | 50,000 | 275,500 | 176,531 | Apr 08, 2020, 08:12 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Apr 06, 2020 | Sale | $17.26 | 50,000 | 863,000 | 126,531 | Apr 08, 2020, 08:12 PM |
| WYSZOMIERSKI JACK L | Director | Apr 03, 2020 | Option Exercise | $5.03 | 45,000 | 226,200 | 175,526 | Apr 03, 2020, 08:38 PM |
| WYSZOMIERSKI JACK L | Director | Apr 03, 2020 | Sale | $16.57 | 13,848 | 229,461 | 161,678 | Apr 03, 2020, 08:38 PM |
| SCANGOS GEORGE A | Director | Mar 31, 2020 | Sale | $18.06 | 1,500 | 27,090 | 961,531 | Apr 02, 2020, 08:08 PM |
| Haley Patrick J. | EVP, Commercial | Mar 20, 2020 | Sale | $15.37 | 4,318 | 66,368 | 116,873 | Mar 20, 2020, 09:03 PM |
| MORRISSEY MICHAEL | President and CEO | Mar 04, 2020 | Option Exercise | $19.89 | 32,884 | 654,063 | 103,101 | Mar 06, 2020, 08:07 PM |
| MORRISSEY MICHAEL | President and CEO | Mar 04, 2020 | Option Exercise | $5.51 | 50,000 | 275,500 | 135,985 | Mar 06, 2020, 08:07 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Mar 04, 2020 | Option Exercise | $1.70 | 100,000 | 170,000 | 425,122 | Mar 06, 2020, 08:01 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Mar 04, 2020 | Sale | $19.40 | 100,000 | 1,940,000 | 375,122 | Mar 06, 2020, 08:01 PM |
| FELDBAUM CARL B | Director | Mar 03, 2020 | Option Exercise | $5.62 | 38,000 | 213,720 | 46,521 | Mar 05, 2020, 08:00 PM |
| FELDBAUM CARL B | Director | Mar 03, 2020 | Sale | $18.84 | 38,000 | 716,013 | 9,174 | Mar 05, 2020, 08:00 PM |
| COHEN CHARLES | Director | Feb 28, 2020 | Option Exercise | $5.03 | 45,000 | 226,200 | 65,979 | Mar 02, 2020, 09:14 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 26, 2020 | Option Exercise | $5.51 | 25,000 | 137,750 | 110,985 | Feb 28, 2020, 08:05 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 26, 2020 | Sale | $18.91 | 25,000 | 472,850 | 86,485 | Feb 28, 2020, 08:05 PM |
| SCANGOS GEORGE A | Director | Feb 18, 2020 | Sale | $20.73 | 50,000 | 1,036,500 | 963,031 | Feb 21, 2020, 08:28 PM |
| Haley Patrick J. | EVP, Commercial | Feb 19, 2020 | Sale | $22.00 | 5,000 | 110,000 | 121,191 | Feb 21, 2020, 08:17 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 19, 2020 | Sale | $21.75 | 25,000 | 543,750 | 85,985 | Feb 21, 2020, 08:03 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 19, 2020 | Option Exercise | $5.51 | 40,000 | 220,400 | 365,122 | Feb 21, 2020, 08:00 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 19, 2020 | Sale | $21.50 | 40,000 | 860,000 | 325,122 | Feb 21, 2020, 08:00 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 13, 2020 | Option Exercise | $5.51 | 25,000 | 137,750 | 110,985 | Feb 14, 2020, 08:48 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 13, 2020 | Sale | $20.11 | 25,000 | 502,750 | 85,985 | Feb 14, 2020, 08:48 PM |
| Garber Alan M | Director | Feb 14, 2020 | Sale | $21.02 | 12,500 | 262,750 | 48,829 | Feb 14, 2020, 08:36 PM |
| SCANGOS GEORGE A | Director | Feb 11, 2020 | Sale | $20.14 | 4,000 | 80,560 | 1,034,031 | Feb 12, 2020, 08:21 PM |
| SCANGOS GEORGE A | Director | Feb 12, 2020 | Sale | $20.02 | 21,000 | 420,420 | 1,013,031 | Feb 12, 2020, 08:21 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 07, 2020 | Option Exercise | $5.51 | 50,000 | 275,500 | 375,122 | Feb 07, 2020, 08:43 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 07, 2020 | Sale | $18.37 | 50,000 | 918,500 | 325,122 | Feb 07, 2020, 08:43 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 29, 2020 | Option Exercise | $5.51 | 25,000 | 137,750 | 110,985 | Jan 31, 2020, 08:03 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 29, 2020 | Sale | $17.87 | 25,000 | 446,750 | 85,985 | Jan 31, 2020, 08:03 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 23, 2020 | Option Exercise | $5.51 | 25,000 | 137,750 | 110,985 | Jan 24, 2020, 08:19 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 23, 2020 | Sale | $19.41 | 25,000 | 485,250 | 85,985 | Jan 24, 2020, 08:19 PM |
| SCANGOS GEORGE A | Director | Jan 22, 2020 | Sale | $19.75 | 25,000 | 493,750 | 1,038,031 | Jan 24, 2020, 08:17 PM |
| MARCHESI VINCENT T | Director | Jan 15, 2020 | Sale | $20.01 | 61,683 | 1,234,277 | 82,484 | Jan 17, 2020, 08:50 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 16, 2020 | Option Exercise | $5.51 | 25,000 | 137,750 | 110,985 | Jan 17, 2020, 08:45 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 16, 2020 | Sale | $20.33 | 25,000 | 508,250 | 85,985 | Jan 17, 2020, 08:45 PM |
| SCANGOS GEORGE A | Director | Jan 15, 2020 | Sale | $20.39 | 25,000 | 509,750 | 1,063,031 | Jan 17, 2020, 08:42 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 08, 2020 | Option Exercise | $5.51 | 25,000 | 137,750 | 110,985 | Jan 09, 2020, 08:35 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 08, 2020 | Sale | $18.85 | 25,000 | 471,250 | 85,985 | Jan 09, 2020, 08:35 PM |
| Garber Alan M | Director | Jan 07, 2020 | Option Exercise | $5.39 | 86,956 | 468,884 | 148,285 | Jan 09, 2020, 08:31 PM |
| Garber Alan M | Director | Jan 07, 2020 | Sale | $18.01 | 86,956 | 1,566,078 | 61,329 | Jan 09, 2020, 08:31 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Jan 07, 2020 | Option Exercise | $5.51 | 50,000 | 275,500 | 375,122 | Jan 09, 2020, 08:27 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Jan 07, 2020 | Sale | $17.96 | 50,000 | 898,000 | 325,122 | Jan 09, 2020, 08:27 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 02, 2020 | Option Exercise | $5.51 | 25,000 | 137,750 | 110,985 | Jan 03, 2020, 07:46 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 02, 2020 | Sale | $17.49 | 25,000 | 437,250 | 85,985 | Jan 03, 2020, 07:46 PM |
| SCANGOS GEORGE A | Director | Dec 27, 2019 | Sale | $18.25 | 25,000 | 456,250 | 1,090,531 | Dec 27, 2019, 08:52 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Dec 04, 2019 | Option Exercise | $17.67 | 4,027 | 71,157 | 325,122 | Dec 06, 2019, 07:23 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Dec 04, 2019 | Option Exercise | $17.67 | 2,360 | 41,701 | 237,570 | Dec 06, 2019, 07:21 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Dec 04, 2019 | Option Exercise | $17.67 | 3,872 | 68,418 | 126,531 | Dec 06, 2019, 07:18 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Dec 04, 2019 | Option Exercise | $17.67 | 2,007 | 35,464 | 86,191 | Dec 06, 2019, 07:16 PM |
| Senner Christopher J. | EVP and CFO | Dec 04, 2019 | Option Exercise | $17.67 | 4,090 | 72,270 | 120,703 | Dec 06, 2019, 07:13 PM |
| MORRISSEY MICHAEL | President and CEO | Dec 04, 2019 | Option Exercise | $17.67 | 9,788 | 172,954 | 214,114 | Dec 06, 2019, 07:11 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Dec 03, 2019 | Option Exercise | $5.51 | 50,000 | 275,500 | 363,557 | Dec 05, 2019, 08:11 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Dec 03, 2019 | Sale | $16.22 | 50,000 | 811,000 | 313,557 | Dec 05, 2019, 08:11 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Nov 15, 2019 | Option Exercise | $16.51 | 8,688 | 143,439 | 233,065 | Nov 15, 2019, 09:42 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Nov 15, 2019 | Option Exercise | $16.51 | 12,268 | 202,545 | 316,140 | Nov 15, 2019, 09:39 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Nov 15, 2019 | Option Exercise | $16.51 | 9,201 | 151,909 | 117,509 | Nov 15, 2019, 09:37 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 15, 2019 | Option Exercise | $16.51 | 18,428 | 304,246 | 194,619 | Nov 15, 2019, 09:34 PM |
| Senner Christopher J. | EVP and CFO | Nov 15, 2019 | Option Exercise | $16.51 | 10,819 | 178,622 | 111,824 | Nov 15, 2019, 09:31 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Nov 15, 2019 | Option Exercise | $16.51 | 9,107 | 150,357 | 83,011 | Nov 15, 2019, 09:28 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Nov 04, 2019 | Option Exercise | $5.51 | 50,000 | 275,500 | 374,331 | Nov 06, 2019, 07:55 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Nov 04, 2019 | Sale | $15.99 | 50,000 | 799,500 | 324,331 | Nov 06, 2019, 07:55 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Oct 10, 2019 | Sale | $16.27 | 303 | 4,930 | 89,209 | Oct 11, 2019, 08:20 PM |
| MORRISSEY MICHAEL | President and CEO | Oct 02, 2019 | Option Exercise | $7.18 | 35,409 | 254,237 | 231,513 | Oct 04, 2019, 08:02 PM |
| MORRISSEY MICHAEL | President and CEO | Oct 02, 2019 | Sale | $17.66 | 26,364 | 465,588 | 205,149 | Oct 04, 2019, 08:02 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Oct 01, 2019 | Option Exercise | $5.51 | 30,000 | 165,300 | 354,331 | Oct 03, 2019, 09:03 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Oct 01, 2019 | Sale | $17.87 | 30,000 | 536,100 | 324,331 | Oct 03, 2019, 09:03 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 18, 2019 | Option Exercise | $7.18 | 50,000 | 359,000 | 233,331 | Sep 20, 2019, 08:05 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 18, 2019 | Sale | $19.20 | 37,227 | 714,758 | 196,104 | Sep 20, 2019, 08:05 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 12, 2019 | Option Exercise | $19.26 | 1,487 | 28,640 | 238,330 | Sep 13, 2019, 08:49 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Sep 12, 2019 | Option Exercise | $19.26 | 2,581 | 49,710 | 124,611 | Sep 13, 2019, 08:47 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 12, 2019 | Option Exercise | $19.26 | 6,526 | 125,691 | 183,331 | Sep 13, 2019, 08:45 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Sep 12, 2019 | Option Exercise | $19.26 | 1,338 | 25,770 | 89,512 | Sep 13, 2019, 08:42 PM |
| Senner Christopher J. | EVP and CFO | Sep 12, 2019 | Option Exercise | $19.26 | 2,737 | 52,715 | 120,020 | Sep 13, 2019, 08:22 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Sep 12, 2019 | Option Exercise | $19.26 | 2,577 | 49,633 | 324,331 | Sep 13, 2019, 08:13 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Sep 10, 2019 | Sale | $18.84 | 1,000 | 18,840 | 85,453 | Sep 12, 2019, 08:07 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Aug 16, 2019 | Option Exercise | $1.70 | 75,000 | 127,500 | 308,820 | Aug 20, 2019, 08:39 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Aug 16, 2019 | Sale | $21.10 | 75,000 | 1,582,500 | 233,820 | Aug 20, 2019, 08:39 PM |
| POSTE GEORGE | Director | Aug 16, 2019 | Option Exercise | $4.58 | 25,000 | 114,500 | 137,792 | Aug 19, 2019, 08:18 PM |
| POSTE GEORGE | Director | Aug 16, 2019 | Sale | $20.50 | 25,000 | 512,500 | 112,792 | Aug 19, 2019, 08:18 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 14, 2019 | Option Exercise | $7.18 | 50,000 | 359,000 | 200,109 | Aug 16, 2019, 08:02 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 14, 2019 | Sale | $20.11 | 35,040 | 704,654 | 165,069 | Aug 16, 2019, 08:02 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Aug 12, 2019 | Sale | $20.39 | 1,000 | 20,390 | 86,453 | Aug 14, 2019, 08:00 PM |
| POSTE GEORGE | Director | Aug 09, 2019 | Option Exercise | $5.59 | 20,000 | 111,700 | 132,792 | Aug 09, 2019, 07:55 PM |
| POSTE GEORGE | Director | Aug 09, 2019 | Sale | $20.60 | 20,000 | 412,000 | 112,792 | Aug 09, 2019, 07:55 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Aug 06, 2019 | Option Exercise | $1.70 | 25,000 | 42,500 | 112,453 | Aug 08, 2019, 08:13 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Aug 06, 2019 | Sale | $20.02 | 25,000 | 500,500 | 87,453 | Aug 08, 2019, 08:13 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 02, 2019 | Option Exercise | $7.18 | 50,000 | 359,000 | 185,149 | Aug 02, 2019, 08:29 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 02, 2019 | Sale | $20.25 | 35,040 | 709,560 | 150,109 | Aug 02, 2019, 08:29 PM |
| SCANGOS GEORGE A | Director | Aug 01, 2019 | Sale | $20.59 | 40,000 | 823,737 | 1,134,081 | Aug 02, 2019, 08:27 PM |
| MORRISSEY MICHAEL | President and CEO | Jul 17, 2019 | Option Exercise | $7.18 | 50,000 | 359,000 | 169,870 | Jul 19, 2019, 08:04 PM |
| MORRISSEY MICHAEL | President and CEO | Jul 17, 2019 | Sale | $21.37 | 34,721 | 741,988 | 135,149 | Jul 19, 2019, 08:04 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jul 10, 2019 | Sale | $20.96 | 1,000 | 20,960 | 87,453 | Jul 12, 2019, 07:53 PM |
| SCANGOS GEORGE A | Director | Jul 01, 2019 | Sale | $21.58 | 40,000 | 863,200 | 1,168,031 | Jul 03, 2019, 08:13 PM |
| MORRISSEY MICHAEL | President and CEO | Jul 03, 2019 | Option Exercise | $7.18 | 50,000 | 359,000 | 154,591 | Jul 03, 2019, 08:11 PM |
| MORRISSEY MICHAEL | President and CEO | Jul 03, 2019 | Sale | $21.03 | 34,721 | 730,183 | 119,870 | Jul 03, 2019, 08:11 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 19, 2019 | Option Exercise | $5.51 | 17,404 | 95,896 | 134,601 | Jun 19, 2019, 09:30 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 18, 2019 | Option Exercise | $2.64 | 100,000 | 263,711 | 217,197 | Jun 19, 2019, 09:30 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 17, 2019 | Option Exercise | $5.38 | 100,000 | 538,259 | 217,197 | Jun 19, 2019, 09:30 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 18, 2019 | Sale | $20.67 | 100,000 | 2,067,000 | 117,197 | Jun 19, 2019, 09:30 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 17, 2019 | Sale | $20.53 | 117,404 | 2,410,307 | 117,197 | Jun 19, 2019, 09:30 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 13, 2019 | Option Exercise | $5.56 | 27,596 | 153,434 | 144,793 | Jun 14, 2019, 08:11 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jun 13, 2019 | Sale | $20.03 | 27,596 | 552,748 | 117,197 | Jun 14, 2019, 08:11 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jun 10, 2019 | Sale | $20.23 | 1,000 | 20,230 | 88,453 | Jun 12, 2019, 08:16 PM |
| SCANGOS GEORGE A | Director | Jun 04, 2019 | Sale | $20.00 | 15,000 | 300,000 | 1,208,031 | Jun 05, 2019, 08:21 PM |
| SCANGOS GEORGE A | Director | Jun 03, 2019 | Sale | $19.61 | 25,000 | 490,250 | 1,223,031 | Jun 05, 2019, 08:21 PM |
| MORRISSEY MICHAEL | President and CEO | May 29, 2019 | Option Exercise | $7.18 | 14,591 | 104,763 | 104,591 | May 30, 2019, 08:53 PM |
| SCANGOS GEORGE A | Director | May 21, 2019 | Option Exercise | $4.57 | 15,000 | 68,550 | 1,248,031 | May 22, 2019, 08:52 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | May 10, 2019 | Sale | $19.58 | 1,000 | 19,580 | 89,453 | May 10, 2019, 08:35 PM |
| MORRISSEY MICHAEL | President and CEO | May 08, 2019 | Option Exercise | $5.56 | 42,000 | 233,520 | 132,000 | May 10, 2019, 08:21 PM |
| MORRISSEY MICHAEL | President and CEO | May 08, 2019 | Sale | $20.15 | 42,000 | 846,300 | 90,000 | May 10, 2019, 08:21 PM |
| WILLSEY LANCE | Director | May 08, 2019 | Sale | $20.36 | 50,000 | 1,018,000 | 368,273 | May 10, 2019, 08:20 PM |
| Senner Christopher J. | EVP and CFO | May 03, 2019 | Sale | $20.70 | 36,261 | 750,603 | 112,362 | May 03, 2019, 08:55 PM |
| SCANGOS GEORGE A | Director | May 02, 2019 | Sale | $20.00 | 15,000 | 300,000 | 1,233,031 | May 03, 2019, 08:52 PM |
| SCANGOS GEORGE A | Director | May 01, 2019 | Sale | $19.75 | 25,000 | 493,750 | 1,248,031 | May 03, 2019, 08:52 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 24, 2019 | Option Exercise | $5.56 | 40,000 | 222,400 | 130,000 | Apr 26, 2019, 08:14 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 24, 2019 | Sale | $20.75 | 40,000 | 830,000 | 90,000 | Apr 26, 2019, 08:14 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Apr 10, 2019 | Sale | $24.04 | 1,000 | 24,040 | 88,780 | Apr 12, 2019, 07:59 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 10, 2019 | Option Exercise | $5.56 | 40,000 | 222,400 | 130,000 | Apr 12, 2019, 07:56 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 10, 2019 | Sale | $24.06 | 40,000 | 962,400 | 90,000 | Apr 12, 2019, 07:56 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Apr 03, 2019 | Option Exercise | $7.18 | 63,109 | 453,123 | 379,622 | Apr 03, 2019, 08:17 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Apr 03, 2019 | Sale | $25.00 | 63,109 | 1,577,725 | 316,513 | Apr 03, 2019, 08:17 PM |
| WYSZOMIERSKI JACK L | Director | Apr 01, 2019 | Option Exercise | $4.39 | 26,250 | 115,350 | 128,031 | Apr 03, 2019, 08:09 PM |
| WYSZOMIERSKI JACK L | Director | Apr 01, 2019 | Sale | $23.97 | 7,822 | 187,493 | 120,209 | Apr 03, 2019, 08:09 PM |
| SCANGOS GEORGE A | Director | Apr 03, 2019 | Sale | $25.03 | 5,000 | 125,150 | 1,273,031 | Apr 03, 2019, 08:05 PM |
| SCANGOS GEORGE A | Director | Apr 01, 2019 | Sale | $24.02 | 40,000 | 960,800 | 1,278,031 | Apr 03, 2019, 08:05 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Apr 01, 2019 | Option Exercise | $1.70 | 20,000 | 34,000 | 253,820 | Apr 03, 2019, 08:01 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Apr 01, 2019 | Sale | $24.03 | 20,000 | 480,600 | 233,820 | Apr 03, 2019, 08:01 PM |
| Garber Alan M | Director | Apr 01, 2019 | Option Exercise | $5.25 | 30,000 | 157,350 | 76,329 | Apr 03, 2019, 07:58 PM |
| Garber Alan M | Director | Apr 01, 2019 | Sale | $23.98 | 30,000 | 719,550 | 61,329 | Apr 03, 2019, 07:58 PM |
| MORRISSEY MICHAEL | President and CEO | Mar 27, 2019 | Option Exercise | $5.56 | 40,000 | 222,400 | 130,000 | Mar 29, 2019, 07:41 PM |
| MORRISSEY MICHAEL | President and CEO | Mar 27, 2019 | Sale | $23.39 | 40,000 | 935,600 | 90,000 | Mar 29, 2019, 07:41 PM |
| POSTE GEORGE | Director | Mar 29, 2019 | Option Exercise | $4.57 | 15,000 | 68,550 | 106,335 | Mar 29, 2019, 07:37 PM |
| POSTE GEORGE | Director | Mar 29, 2019 | Sale | $23.89 | 3,860 | 92,215 | 102,475 | Mar 29, 2019, 07:37 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Mar 25, 2019 | Option Exercise | $7.18 | 100,000 | 718,000 | 416,513 | Mar 27, 2019, 08:33 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Mar 25, 2019 | Sale | $23.14 | 100,000 | 2,314,000 | 316,513 | Mar 27, 2019, 08:33 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Mar 26, 2019 | Option Exercise | $5.18 | 2,700 | 13,986 | 92,480 | Mar 27, 2019, 08:31 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Mar 26, 2019 | Sale | $23.47 | 2,700 | 63,369 | 89,780 | Mar 27, 2019, 08:31 PM |
| SCANGOS GEORGE A | Director | Mar 14, 2019 | Sale | $25.00 | 5,000 | 125,000 | 1,318,031 | Mar 15, 2019, 08:25 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Mar 14, 2019 | Option Exercise | $1.76 | 2,000 | 3,520 | 91,780 | Mar 15, 2019, 08:10 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Mar 14, 2019 | Sale | $25.00 | 2,000 | 50,000 | 89,780 | Mar 15, 2019, 08:10 PM |
| MORRISSEY MICHAEL | President and CEO | Mar 13, 2019 | Option Exercise | $5.56 | 40,000 | 222,400 | 130,000 | Mar 15, 2019, 08:07 PM |
| MORRISSEY MICHAEL | President and CEO | Mar 13, 2019 | Sale | $24.64 | 40,000 | 985,485 | 118,367 | Mar 15, 2019, 08:07 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Mar 11, 2019 | Sale | $23.13 | 959 | 22,182 | 89,780 | Mar 13, 2019, 08:03 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 27, 2019 | Option Exercise | $5.56 | 40,000 | 222,400 | 130,000 | Mar 01, 2019, 08:19 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 27, 2019 | Sale | $22.69 | 40,000 | 907,600 | 90,000 | Mar 01, 2019, 08:19 PM |
| SCANGOS GEORGE A | Director | Mar 01, 2019 | Sale | $22.66 | 40,000 | 906,400 | 1,323,031 | Mar 01, 2019, 08:17 PM |
| COHEN CHARLES | Director | Feb 25, 2019 | Option Exercise | $4.39 | 26,250 | 115,350 | 26,250 | Feb 27, 2019, 08:30 PM |
| COHEN CHARLES | Director | Feb 25, 2019 | Sale | $22.18 | 5,271 | 116,911 | 20,979 | Feb 27, 2019, 08:30 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Feb 25, 2019 | Sale | $22.27 | 4,272 | 95,137 | 90,739 | Feb 27, 2019, 08:28 PM |
| PAPADOPOULOS STELIOS | Director | Feb 21, 2019 | Option Exercise | $4.39 | 26,250 | 115,350 | 1,068,501 | Feb 22, 2019, 07:35 PM |
| PAPADOPOULOS STELIOS | Director | Feb 21, 2019 | Sale | $21.25 | 26,250 | 557,813 | 1,042,251 | Feb 22, 2019, 07:35 PM |
| WILLSEY LANCE | Director | Feb 20, 2019 | Option Exercise | $4.39 | 26,250 | 115,350 | 444,523 | Feb 22, 2019, 07:33 PM |
| WILLSEY LANCE | Director | Feb 20, 2019 | Sale | $21.11 | 26,250 | 554,138 | 418,273 | Feb 22, 2019, 07:33 PM |
| MARCHESI VINCENT T | Director | Feb 22, 2019 | Option Exercise | $4.95 | 41,250 | 204,150 | 175,100 | Feb 22, 2019, 07:32 PM |
| MARCHESI VINCENT T | Director | Feb 22, 2019 | Sale | $21.50 | 41,250 | 886,875 | 133,850 | Feb 22, 2019, 07:32 PM |
| COHEN CHARLES | Director | Feb 19, 2019 | Sale | $21.48 | 48,180 | 1,034,906 | 0 | Feb 19, 2019, 08:10 PM |
| COHEN CHARLES | Director | Feb 15, 2019 | Sale | $22.19 | 100,000 | 2,219,000 | 48,180 | Feb 19, 2019, 08:10 PM |
| COHEN CHARLES | Director | Feb 14, 2019 | Sale | $22.41 | 100,000 | 2,241,000 | 148,180 | Feb 19, 2019, 08:10 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 14, 2019 | Option Exercise | $5.56 | 40,000 | 222,400 | 130,000 | Feb 15, 2019, 08:14 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 14, 2019 | Sale | $22.39 | 40,000 | 895,654 | 90,200 | Feb 15, 2019, 08:14 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 14, 2019 | Option Exercise | $5.56 | 100,000 | 556,000 | 416,513 | Feb 15, 2019, 08:11 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 15, 2019 | Option Exercise | $5.56 | 23,000 | 127,880 | 339,513 | Feb 15, 2019, 08:11 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 14, 2019 | Sale | $21.66 | 100,000 | 2,166,000 | 316,513 | Feb 15, 2019, 08:11 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Feb 15, 2019 | Sale | $22.20 | 23,000 | 510,600 | 316,513 | Feb 15, 2019, 08:11 PM |
| FELDBAUM CARL B | Director | Feb 14, 2019 | Option Exercise | $4.98 | 50,500 | 251,275 | 65,721 | Feb 15, 2019, 08:06 PM |
| FELDBAUM CARL B | Director | Feb 14, 2019 | Sale | $22.03 | 50,500 | 1,112,515 | 15,221 | Feb 15, 2019, 08:06 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Feb 11, 2019 | Sale | $21.30 | 1,000 | 21,300 | 95,011 | Feb 13, 2019, 08:36 PM |
| SCANGOS GEORGE A | Director | Feb 01, 2019 | Sale | $23.53 | 40,000 | 941,200 | 1,363,031 | Feb 01, 2019, 08:03 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 30, 2019 | Option Exercise | $5.56 | 40,000 | 222,400 | 130,000 | Feb 01, 2019, 07:58 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 30, 2019 | Sale | $23.12 | 40,000 | 924,800 | 90,000 | Feb 01, 2019, 07:58 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 16, 2019 | Option Exercise | $5.56 | 40,000 | 222,400 | 130,000 | Jan 18, 2019, 08:16 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 16, 2019 | Sale | $23.29 | 40,000 | 931,456 | 90,400 | Jan 18, 2019, 08:16 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jan 10, 2019 | Option Exercise | $1.76 | 2,000 | 3,520 | 99,011 | Jan 11, 2019, 07:56 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jan 10, 2019 | Sale | $23.85 | 3,000 | 71,540 | 97,011 | Jan 11, 2019, 07:56 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jan 07, 2019 | Option Exercise | $2.90 | 5,560 | 16,119 | 101,011 | Jan 09, 2019, 07:49 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jan 09, 2019 | Option Exercise | $5.82 | 1,560 | 9,079 | 98,571 | Jan 09, 2019, 07:49 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jan 08, 2019 | Option Exercise | $1.76 | 2,000 | 3,520 | 99,011 | Jan 09, 2019, 07:49 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jan 09, 2019 | Sale | $23.50 | 1,560 | 36,660 | 97,011 | Jan 09, 2019, 07:49 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jan 08, 2019 | Sale | $23.00 | 2,000 | 46,000 | 97,011 | Jan 09, 2019, 07:49 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jan 07, 2019 | Sale | $21.51 | 5,560 | 119,620 | 97,011 | Jan 09, 2019, 07:49 PM |
| Garber Alan M | Director | Jan 08, 2019 | Option Exercise | $4.16 | 11,250 | 46,800 | 72,579 | Jan 09, 2019, 07:47 PM |
| Garber Alan M | Director | Jan 08, 2019 | Sale | $23.00 | 11,250 | 258,750 | 61,329 | Jan 09, 2019, 07:47 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 03, 2019 | Option Exercise | $5.56 | 3,571 | 19,855 | 93,571 | Jan 04, 2019, 08:50 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 02, 2019 | Option Exercise | $5.56 | 6,046 | 33,616 | 96,046 | Jan 04, 2019, 08:50 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 04, 2019 | Option Exercise | $5.56 | 30,383 | 168,929 | 120,383 | Jan 04, 2019, 08:50 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 02, 2019 | Sale | $20.00 | 6,046 | 120,920 | 90,000 | Jan 04, 2019, 08:50 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 04, 2019 | Sale | $20.14 | 30,383 | 611,914 | 90,000 | Jan 04, 2019, 08:50 PM |
| MORRISSEY MICHAEL | President and CEO | Jan 03, 2019 | Sale | $20.00 | 3,571 | 71,420 | 90,000 | Jan 04, 2019, 08:50 PM |
| SCANGOS GEORGE A | Director | Jan 03, 2019 | Sale | $20.00 | 96 | 1,920 | 1,403,031 | Jan 04, 2019, 08:18 PM |
| SCANGOS GEORGE A | Director | Jan 02, 2019 | Sale | $19.64 | 39,904 | 783,715 | 1,403,127 | Jan 04, 2019, 08:18 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jan 03, 2019 | Option Exercise | $1.76 | 8,000 | 14,080 | 105,011 | Jan 04, 2019, 08:15 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Jan 03, 2019 | Sale | $19.95 | 8,000 | 159,600 | 97,011 | Jan 04, 2019, 08:15 PM |
| SCANGOS GEORGE A | Director | Nov 29, 2018 | Sale | $20.00 | 6,500 | 130,000 | 1,505,481 | Dec 03, 2018, 08:03 PM |
| SCANGOS GEORGE A | Director | Dec 03, 2018 | Sale | $21.16 | 40,000 | 846,400 | 1,456,981 | Dec 03, 2018, 08:03 PM |
| SCANGOS GEORGE A | Director | Nov 30, 2018 | Sale | $20.00 | 8,500 | 170,000 | 1,496,981 | Dec 03, 2018, 08:03 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Dec 03, 2018 | Option Exercise | $5.04 | 13,499 | 68,035 | 330,012 | Dec 03, 2018, 08:00 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Dec 03, 2018 | Sale | $21.02 | 13,499 | 283,749 | 316,513 | Dec 03, 2018, 08:00 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Nov 30, 2018 | Sale | $19.91 | 1,943 | 38,685 | 233,820 | Nov 30, 2018, 08:02 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Nov 29, 2018 | Sale | $19.51 | 1,116 | 21,773 | 235,763 | Nov 30, 2018, 08:02 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Nov 28, 2018 | Sale | $19.12 | 11,759 | 224,832 | 236,879 | Nov 30, 2018, 08:02 PM |
| Senner Christopher J. | EVP and CFO | Nov 30, 2018 | Sale | $19.70 | 8,791 | 173,183 | 146,950 | Nov 30, 2018, 08:00 PM |
| Senner Christopher J. | EVP and CFO | Nov 15, 2018 | Option Exercise | $17.45 | 7,764 | 135,482 | 157,623 | Nov 16, 2018, 08:26 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Nov 15, 2018 | Option Exercise | $17.45 | 11,775 | 205,474 | 318,992 | Nov 16, 2018, 08:24 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 15, 2018 | Option Exercise | $17.45 | 17,353 | 302,810 | 115,084 | Nov 16, 2018, 08:22 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 15, 2018 | Option Exercise | $4.42 | 25,000 | 110,500 | 132,647 | Nov 16, 2018, 08:22 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 15, 2018 | Sale | $17.22 | 25,000 | 430,500 | 107,647 | Nov 16, 2018, 08:22 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Nov 15, 2018 | Option Exercise | $17.45 | 9,199 | 160,523 | 119,295 | Nov 16, 2018, 08:19 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Nov 15, 2018 | Option Exercise | $17.45 | 5,812 | 101,419 | 250,042 | Nov 16, 2018, 08:16 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Nov 15, 2018 | Option Exercise | $17.45 | 9,106 | 158,900 | 99,920 | Nov 16, 2018, 08:12 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Nov 07, 2018 | Sale | $17.32 | 20,000 | 346,400 | 104,917 | Nov 09, 2018, 07:56 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Nov 01, 2018 | Option Exercise | $5.04 | 12,000 | 60,480 | 340,288 | Nov 02, 2018, 08:05 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Nov 01, 2018 | Sale | $14.16 | 12,000 | 169,920 | 328,288 | Nov 02, 2018, 08:05 PM |
| SCANGOS GEORGE A | Director | Nov 01, 2018 | Sale | $14.66 | 25,000 | 366,400 | 1,521,981 | Nov 02, 2018, 08:03 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 02, 2018 | Option Exercise | $5.04 | 37,499 | 188,995 | 162,499 | Nov 02, 2018, 08:02 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 02, 2018 | Sale | $17.57 | 37,499 | 658,964 | 129,144 | Nov 02, 2018, 08:02 PM |
| SCANGOS GEORGE A | Director | Oct 01, 2018 | Sale | $17.86 | 25,000 | 446,500 | 1,536,981 | Oct 03, 2018, 08:12 PM |
| MORRISSEY MICHAEL | President and CEO | Oct 01, 2018 | Option Exercise | $5.04 | 12,501 | 63,005 | 137,501 | Oct 03, 2018, 08:11 PM |
| MORRISSEY MICHAEL | President and CEO | Oct 01, 2018 | Sale | $17.82 | 12,501 | 222,768 | 125,000 | Oct 03, 2018, 08:11 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Oct 01, 2018 | Option Exercise | $5.04 | 12,000 | 60,480 | 340,288 | Oct 03, 2018, 08:08 PM |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | Oct 01, 2018 | Sale | $17.77 | 12,000 | 213,240 | 328,288 | Oct 03, 2018, 08:08 PM |
| SCANGOS GEORGE A | Director | Sep 24, 2018 | Sale | $16.85 | 25,000 | 421,250 | 1,561,981 | Sep 26, 2018, 07:40 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Sep 04, 2018 | Option Exercise | $5.50 | 22,500 | 123,750 | 350,788 | Sep 06, 2018, 08:00 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Sep 04, 2018 | Sale | $18.53 | 22,500 | 416,925 | 328,288 | Sep 06, 2018, 08:00 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 20, 2018 | Option Exercise | $5.50 | 90,000 | 495,000 | 215,000 | Aug 22, 2018, 08:10 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 20, 2018 | Sale | $17.82 | 90,000 | 1,604,216 | 211,200 | Aug 22, 2018, 08:10 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Aug 17, 2018 | Option Exercise | $5.51 | 50,000 | 275,500 | 328,288 | Aug 20, 2018, 08:10 PM |
| MARCHESI VINCENT T | Director | Aug 15, 2018 | Option Exercise | $3.38 | 40,000 | 135,200 | 173,850 | Aug 17, 2018, 07:39 PM |
| MARCHESI VINCENT T | Director | Aug 15, 2018 | Sale | $19.50 | 40,000 | 780,000 | 133,850 | Aug 17, 2018, 07:39 PM |
| SCANGOS GEORGE A | Director | Aug 10, 2018 | Option Exercise | $4.85 | 108,333 | 525,332 | 1,586,981 | Aug 10, 2018, 09:25 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 07, 2018 | Option Exercise | $1.70 | 100,000 | 170,000 | 225,000 | Aug 09, 2018, 07:35 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 09, 2018 | Option Exercise | $1.70 | 34,267 | 58,254 | 159,267 | Aug 09, 2018, 07:35 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 08, 2018 | Option Exercise | $1.70 | 100,000 | 170,000 | 225,000 | Aug 09, 2018, 07:35 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 07, 2018 | Sale | $21.10 | 100,000 | 2,110,000 | 125,000 | Aug 09, 2018, 07:35 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 09, 2018 | Sale | $20.91 | 34,267 | 716,523 | 125,000 | Aug 09, 2018, 07:35 PM |
| MORRISSEY MICHAEL | President and CEO | Aug 08, 2018 | Sale | $21.02 | 100,000 | 2,102,000 | 125,000 | Aug 09, 2018, 07:35 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Aug 06, 2018 | Sale | $20.92 | 2,361 | 49,392 | 124,917 | Aug 08, 2018, 07:26 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Aug 01, 2018 | Option Exercise | $5.50 | 22,500 | 123,750 | 300,788 | Aug 03, 2018, 07:13 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Aug 01, 2018 | Sale | $20.56 | 22,500 | 462,600 | 278,288 | Aug 03, 2018, 07:13 PM |
| MORRISSEY MICHAEL | President and CEO | Jul 16, 2018 | Option Exercise | $5.50 | 90,000 | 495,000 | 215,000 | Jul 17, 2018, 08:19 PM |
| MORRISSEY MICHAEL | President and CEO | Jul 16, 2018 | Sale | $21.13 | 90,000 | 1,901,700 | 125,000 | Jul 17, 2018, 08:19 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Jul 02, 2018 | Option Exercise | $5.50 | 22,500 | 123,750 | 300,788 | Jul 03, 2018, 09:07 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Jul 02, 2018 | Sale | $21.20 | 22,500 | 477,000 | 278,288 | Jul 03, 2018, 09:07 PM |
| MORRISSEY MICHAEL | President and CEO | Jun 25, 2018 | Option Exercise | $5.50 | 90,000 | 495,000 | 215,000 | Jun 27, 2018, 08:12 PM |
| MORRISSEY MICHAEL | President and CEO | Jun 25, 2018 | Sale | $19.62 | 90,000 | 1,765,800 | 125,000 | Jun 27, 2018, 08:12 PM |
| Hessekiel Jeffrey | EVP and General Counsel | May 31, 2018 | Sale | $20.71 | 65,000 | 1,346,150 | 254,450 | Jun 01, 2018, 08:00 PM |
| FELDBAUM CARL B | Director | May 30, 2018 | Option Exercise | $4.26 | 14,750 | 62,795 | 49,483 | Jun 01, 2018, 07:59 PM |
| FELDBAUM CARL B | Director | May 30, 2018 | Sale | $20.60 | 34,262 | 705,797 | 15,221 | Jun 01, 2018, 07:59 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Jun 01, 2018 | Option Exercise | $5.50 | 22,500 | 123,750 | 300,788 | Jun 01, 2018, 07:58 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Jun 01, 2018 | Sale | $20.80 | 22,500 | 468,000 | 278,288 | Jun 01, 2018, 07:58 PM |
| WILLSEY LANCE | Director | May 22, 2018 | Sale | $21.40 | 50,000 | 1,070,000 | 418,273 | May 24, 2018, 08:24 PM |
| MORRISSEY MICHAEL | President and CEO | May 24, 2018 | Option Exercise | $5.50 | 90,000 | 495,000 | 215,000 | May 24, 2018, 08:16 PM |
| MORRISSEY MICHAEL | President and CEO | May 24, 2018 | Sale | $20.55 | 90,000 | 1,849,500 | 125,000 | May 24, 2018, 08:16 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | May 18, 2018 | Sale | $21.61 | 3,663 | 79,157 | 127,278 | May 18, 2018, 08:02 PM |
| SCANGOS GEORGE A | Director | May 15, 2018 | Option Exercise | $11.66 | 15,000 | 174,900 | 1,478,648 | May 16, 2018, 07:59 PM |
| MARCHESI VINCENT T | Director | May 11, 2018 | Option Exercise | $11.66 | 15,000 | 174,900 | 140,913 | May 11, 2018, 07:58 PM |
| MARCHESI VINCENT T | Director | May 11, 2018 | Sale | $19.03 | 15,000 | 285,450 | 125,913 | May 11, 2018, 07:58 PM |
| COHEN CHARLES | Director | May 09, 2018 | Option Exercise | $11.66 | 15,000 | 174,900 | 263,180 | May 10, 2018, 08:03 PM |
| COHEN CHARLES | Director | May 09, 2018 | Sale | $21.42 | 15,000 | 321,300 | 248,180 | May 10, 2018, 08:03 PM |
| PAPADOPOULOS STELIOS | Director | May 07, 2018 | Option Exercise | $11.66 | 15,000 | 174,900 | 1,049,314 | May 07, 2018, 08:07 PM |
| PAPADOPOULOS STELIOS | Director | May 07, 2018 | Sale | $22.15 | 15,000 | 332,250 | 1,034,314 | May 07, 2018, 08:07 PM |
| Hessekiel Jeffrey | EVP and General Counsel | May 04, 2018 | Sale | $22.36 | 20,000 | 447,200 | 319,450 | May 07, 2018, 08:07 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | May 07, 2018 | Option Exercise | $1.90 | 15,000 | 28,500 | 145,941 | May 07, 2018, 08:06 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | May 04, 2018 | Option Exercise | $1.90 | 10,000 | 19,000 | 143,490 | May 07, 2018, 08:06 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | May 07, 2018 | Sale | $22.00 | 15,000 | 330,000 | 130,941 | May 07, 2018, 08:06 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | May 04, 2018 | Sale | $22.38 | 12,549 | 280,847 | 130,941 | May 07, 2018, 08:06 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | May 03, 2018 | Option Exercise | $5.50 | 22,500 | 123,750 | 300,788 | May 04, 2018, 07:06 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | May 03, 2018 | Sale | $23.09 | 22,500 | 519,417 | 292,988 | May 04, 2018, 07:06 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Apr 27, 2018 | Option Exercise | $1.70 | 25,000 | 42,500 | 339,450 | Apr 30, 2018, 08:23 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Apr 24, 2018 | Option Exercise | $1.70 | 20,000 | 34,000 | 133,490 | Apr 26, 2018, 08:22 PM |
| WYSZOMIERSKI JACK L | Director | Apr 16, 2018 | Option Exercise | $9.81 | 30,000 | 294,450 | 108,803 | Apr 18, 2018, 08:12 PM |
| WYSZOMIERSKI JACK L | Director | Apr 16, 2018 | Sale | $20.25 | 14,959 | 302,920 | 93,844 | Apr 18, 2018, 08:12 PM |
| Garber Alan M | Director | Apr 16, 2018 | Option Exercise | $11.66 | 15,000 | 174,900 | 76,329 | Apr 18, 2018, 08:11 PM |
| Garber Alan M | Director | Apr 16, 2018 | Sale | $20.25 | 15,000 | 303,750 | 61,329 | Apr 18, 2018, 08:11 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 11, 2018 | Option Exercise | $5.50 | 90,000 | 495,000 | 221,653 | Apr 13, 2018, 08:09 PM |
| MORRISSEY MICHAEL | President and CEO | Apr 11, 2018 | Sale | $20.78 | 90,000 | 1,870,200 | 131,653 | Apr 13, 2018, 08:09 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Apr 06, 2018 | Option Exercise | $7.18 | 14,591 | 104,763 | 277,280 | Apr 06, 2018, 07:48 PM |
| FELDBAUM CARL B | Director | Mar 05, 2018 | Option Exercise | $11.66 | 11,000 | 128,260 | 45,733 | Mar 07, 2018, 07:26 PM |
| FELDBAUM CARL B | Director | Mar 05, 2018 | Sale | $23.88 | 11,000 | 262,680 | 34,733 | Mar 07, 2018, 07:26 PM |
| COHEN CHARLES | Director | Mar 05, 2018 | Option Exercise | $7.97 | 15,000 | 119,550 | 263,180 | Mar 07, 2018, 07:25 PM |
| COHEN CHARLES | Director | Mar 05, 2018 | Sale | $24.23 | 15,000 | 363,450 | 248,180 | Mar 07, 2018, 07:25 PM |
| MARCHESI VINCENT T | Director | Mar 06, 2018 | Option Exercise | $7.97 | 15,000 | 119,550 | 140,913 | Mar 07, 2018, 07:23 PM |
| MARCHESI VINCENT T | Director | Mar 06, 2018 | Sale | $24.73 | 15,000 | 370,950 | 125,913 | Mar 07, 2018, 07:23 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Mar 01, 2018 | Option Exercise | $4.42 | 7,293 | 32,235 | 262,689 | Mar 02, 2018, 08:04 PM |
| PAPADOPOULOS STELIOS | Director | Mar 02, 2018 | Option Exercise | $7.97 | 15,000 | 119,550 | 1,049,314 | Mar 02, 2018, 08:03 PM |
| PAPADOPOULOS STELIOS | Director | Mar 02, 2018 | Sale | $24.05 | 15,000 | 360,750 | 1,034,314 | Mar 02, 2018, 08:03 PM |
| WILLSEY LANCE | Director | Mar 02, 2018 | Option Exercise | $9.81 | 30,000 | 294,450 | 498,273 | Mar 02, 2018, 08:01 PM |
| WILLSEY LANCE | Director | Mar 02, 2018 | Sale | $23.91 | 30,000 | 717,300 | 468,273 | Mar 02, 2018, 08:01 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Feb 28, 2018 | Option Exercise | $2.58 | 13,625 | 35,200 | 158,519 | Mar 02, 2018, 08:00 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Feb 28, 2018 | Sale | $27.13 | 45,029 | 1,221,637 | 113,490 | Mar 02, 2018, 08:00 PM |
| POSTE GEORGE | Director | Feb 28, 2018 | Option Exercise | $11.66 | 15,000 | 174,900 | 98,398 | Mar 02, 2018, 07:59 PM |
| POSTE GEORGE | Director | Feb 28, 2018 | Sale | $26.26 | 15,000 | 393,900 | 83,398 | Mar 02, 2018, 07:59 PM |
| Garber Alan M | Director | Jan 09, 2018 | Option Exercise | $7.97 | 11,500 | 91,655 | 72,829 | Jan 10, 2018, 07:27 PM |
| Garber Alan M | Director | Jan 08, 2018 | Option Exercise | $7.97 | 3,500 | 27,895 | 64,829 | Jan 10, 2018, 07:27 PM |
| Garber Alan M | Director | Jan 09, 2018 | Sale | $30.00 | 11,500 | 345,000 | 61,329 | Jan 10, 2018, 07:27 PM |
| Garber Alan M | Director | Jan 08, 2018 | Sale | $31.29 | 3,500 | 109,515 | 61,329 | Jan 10, 2018, 07:27 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Nov 15, 2017 | Option Exercise | $24.75 | 2,204 | 54,549 | 126,396 | Nov 17, 2017, 07:47 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Nov 15, 2017 | Option Exercise | $24.75 | 2,609 | 64,573 | 255,396 | Nov 17, 2017, 07:47 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Nov 15, 2017 | Option Exercise | $24.75 | 3,739 | 92,540 | 91,709 | Nov 17, 2017, 07:46 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Nov 15, 2017 | Option Exercise | $24.75 | 2,120 | 52,470 | 316,942 | Nov 17, 2017, 07:45 PM |
| Senner Christopher J. | EVP and CFO | Nov 15, 2017 | Option Exercise | $24.75 | 2,762 | 68,360 | 162,497 | Nov 17, 2017, 07:44 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 15, 2017 | Option Exercise | $24.75 | 8,347 | 206,588 | 131,653 | Nov 17, 2017, 07:43 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 27, 2017 | Option Exercise | $1.90 | 2,302 | 4,374 | 270,248 | Sep 28, 2017, 07:47 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 28, 2017 | Option Exercise | $1.90 | 25,000 | 47,500 | 292,946 | Sep 28, 2017, 07:47 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 28, 2017 | Sale | $24.32 | 25,000 | 608,000 | 267,946 | Sep 28, 2017, 07:47 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Sep 27, 2017 | Sale | $23.90 | 2,302 | 55,018 | 267,946 | Sep 28, 2017, 07:47 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Sep 26, 2017 | Option Exercise | $9.91 | 33,333 | 330,330 | 216,338 | Sep 28, 2017, 07:45 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Sep 28, 2017 | Option Exercise | $9.91 | 33,334 | 330,340 | 216,339 | Sep 28, 2017, 07:45 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Sep 27, 2017 | Option Exercise | $9.91 | 33,333 | 330,330 | 216,338 | Sep 28, 2017, 07:45 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Sep 28, 2017 | Sale | $23.74 | 33,334 | 791,349 | 183,005 | Sep 28, 2017, 07:45 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Sep 27, 2017 | Sale | $23.94 | 33,333 | 797,992 | 183,005 | Sep 28, 2017, 07:45 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Sep 26, 2017 | Sale | $23.68 | 33,333 | 789,325 | 183,005 | Sep 28, 2017, 07:45 PM |
| PAPADOPOULOS STELIOS | Director | Sep 22, 2017 | Sale | $25.40 | 10,000 | 254,000 | 0 | Sep 22, 2017, 07:07 PM |
| PAPADOPOULOS STELIOS | Director | Sep 19, 2017 | Sale | $27.63 | 127,790 | 3,530,838 | 1,034,314 | Sep 20, 2017, 06:48 PM |
| PAPADOPOULOS STELIOS | Director | Sep 18, 2017 | Sale | $27.76 | 72,210 | 2,004,550 | 1,162,104 | Sep 20, 2017, 06:48 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Sep 14, 2017 | Sale | $27.21 | 60,640 | 1,650,014 | 41,553 | Sep 15, 2017, 06:43 PM |
| WILLSEY LANCE | Director | Sep 13, 2017 | Sale | $26.97 | 50,000 | 1,348,500 | 468,273 | Sep 14, 2017, 07:18 PM |
| WILLSEY LANCE | Director | Sep 12, 2017 | Sale | $26.79 | 50,000 | 1,339,500 | 518,273 | Sep 14, 2017, 07:18 PM |
| Senner Christopher J. | EVP and CFO | Sep 12, 2017 | Option Exercise | $3.66 | 100,000 | 366,000 | 202,759 | Sep 14, 2017, 07:17 PM |
| Senner Christopher J. | EVP and CFO | Sep 12, 2017 | Sale | $26.79 | 100,000 | 2,679,000 | 102,759 | Sep 14, 2017, 07:17 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 12, 2017 | Option Exercise | $1.70 | 100,000 | 170,000 | 160,000 | Sep 14, 2017, 07:14 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 14, 2017 | Option Exercise | $1.70 | 100,000 | 170,000 | 160,000 | Sep 14, 2017, 07:14 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 13, 2017 | Option Exercise | $1.70 | 100,000 | 170,000 | 160,000 | Sep 14, 2017, 07:14 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 14, 2017 | Sale | $27.08 | 100,000 | 2,708,000 | 60,000 | Sep 14, 2017, 07:14 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 13, 2017 | Sale | $27.04 | 100,000 | 2,704,000 | 60,000 | Sep 14, 2017, 07:14 PM |
| MORRISSEY MICHAEL | President and CEO | Sep 12, 2017 | Sale | $26.59 | 100,000 | 2,659,000 | 60,000 | Sep 14, 2017, 07:14 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | May 30, 2017 | Sale | $18.46 | 5,000 | 92,300 | 102,193 | Jun 01, 2017, 07:09 PM |
| FELDBAUM CARL B | Director | May 15, 2017 | Option Exercise | $8.75 | 19,000 | 166,190 | 67,721 | May 16, 2017, 09:13 PM |
| FELDBAUM CARL B | Director | May 15, 2017 | Sale | $21.58 | 32,988 | 711,831 | 48,721 | May 16, 2017, 09:13 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | May 15, 2017 | Option Exercise | $5.04 | 12,501 | 63,005 | 183,005 | May 16, 2017, 09:12 PM |
| MORRISSEY MICHAEL | President and CEO | May 10, 2017 | Option Exercise | $1.86 | 100,000 | 185,910 | 160,000 | May 10, 2017, 08:07 PM |
| MORRISSEY MICHAEL | President and CEO | May 09, 2017 | Option Exercise | $1.90 | 100,000 | 190,000 | 111,214 | May 10, 2017, 08:07 PM |
| MORRISSEY MICHAEL | President and CEO | May 08, 2017 | Option Exercise | $1.90 | 11,300 | 21,470 | 71,300 | May 10, 2017, 08:07 PM |
| MORRISSEY MICHAEL | President and CEO | May 09, 2017 | Sale | $21.69 | 100,000 | 2,168,706 | 60,000 | May 10, 2017, 08:07 PM |
| MORRISSEY MICHAEL | President and CEO | May 08, 2017 | Sale | $21.81 | 11,300 | 246,453 | 60,000 | May 10, 2017, 08:07 PM |
| MORRISSEY MICHAEL | President and CEO | May 10, 2017 | Sale | $22.07 | 100,000 | 2,207,000 | 60,000 | May 10, 2017, 08:07 PM |
| MORRISSEY MICHAEL | President and CEO | May 04, 2017 | Option Exercise | $1.90 | 59,149 | 112,383 | 119,149 | May 05, 2017, 06:53 PM |
| MORRISSEY MICHAEL | President and CEO | May 03, 2017 | Option Exercise | $1.90 | 100,000 | 190,000 | 129,427 | May 05, 2017, 06:53 PM |
| MORRISSEY MICHAEL | President and CEO | May 05, 2017 | Option Exercise | $1.90 | 100,000 | 190,000 | 149,555 | May 05, 2017, 06:53 PM |
| MORRISSEY MICHAEL | President and CEO | May 04, 2017 | Sale | $22.17 | 59,149 | 1,311,333 | 60,000 | May 05, 2017, 06:53 PM |
| MORRISSEY MICHAEL | President and CEO | May 03, 2017 | Sale | $22.67 | 100,000 | 2,266,803 | 60,000 | May 05, 2017, 06:53 PM |
| MORRISSEY MICHAEL | President and CEO | May 05, 2017 | Sale | $21.85 | 100,000 | 2,184,702 | 60,000 | May 05, 2017, 06:53 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | May 01, 2017 | Option Exercise | $9.91 | 89,910 | 891,008 | 260,414 | May 03, 2017, 08:02 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | May 01, 2017 | Sale | $23.01 | 89,910 | 2,068,519 | 172,404 | May 03, 2017, 08:02 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Apr 17, 2017 | Option Exercise | $9.91 | 10,090 | 99,992 | 168,143 | Apr 18, 2017, 07:57 PM |
| MARCHESI VINCENT T | Director | Apr 03, 2017 | Option Exercise | $10.53 | 10,000 | 105,300 | 130,070 | Apr 04, 2017, 08:00 PM |
| MARCHESI VINCENT T | Director | Apr 03, 2017 | Sale | $21.30 | 10,000 | 213,000 | 120,070 | Apr 04, 2017, 08:00 PM |
| WYSZOMIERSKI JACK L | Director | Mar 31, 2017 | Option Exercise | $10.53 | 10,000 | 105,300 | 78,110 | Mar 31, 2017, 06:35 PM |
| WYSZOMIERSKI JACK L | Director | Mar 31, 2017 | Sale | $21.57 | 5,150 | 111,085 | 72,960 | Mar 31, 2017, 06:35 PM |
| COHEN CHARLES | Director | Mar 27, 2017 | Option Exercise | $10.53 | 10,000 | 105,300 | 248,180 | Mar 28, 2017, 08:15 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Mar 27, 2017 | Sale | $21.02 | 6,884 | 144,702 | 267,946 | Mar 28, 2017, 08:15 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Mar 22, 2017 | Option Exercise | $1.70 | 55,000 | 93,500 | 301,617 | Mar 24, 2017, 07:41 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Mar 22, 2017 | Sale | $20.54 | 23,787 | 488,585 | 277,830 | Mar 24, 2017, 07:41 PM |
| FELDBAUM CARL B | Director | Mar 20, 2017 | Option Exercise | $10.53 | 10,000 | 105,300 | 58,721 | Mar 21, 2017, 07:29 PM |
| FELDBAUM CARL B | Director | Mar 20, 2017 | Sale | $21.77 | 10,000 | 217,700 | 48,721 | Mar 21, 2017, 07:29 PM |
| PAPADOPOULOS STELIOS | Director | Mar 20, 2017 | Option Exercise | $10.53 | 10,000 | 105,300 | 1,238,471 | Mar 21, 2017, 07:28 PM |
| PAPADOPOULOS STELIOS | Director | Mar 20, 2017 | Sale | $21.66 | 10,000 | 216,600 | 1,228,471 | Mar 21, 2017, 07:28 PM |
| WILLSEY LANCE | Director | Mar 15, 2017 | Option Exercise | $10.53 | 10,000 | 105,300 | 578,273 | Mar 17, 2017, 07:52 PM |
| WILLSEY LANCE | Director | Mar 15, 2017 | Sale | $22.86 | 10,000 | 228,600 | 568,273 | Mar 17, 2017, 07:52 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Mar 15, 2017 | Option Exercise | $6.20 | 50,007 | 310,179 | 208,060 | Mar 17, 2017, 07:51 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Mar 15, 2017 | Sale | $22.53 | 50,007 | 1,126,658 | 158,053 | Mar 17, 2017, 07:51 PM |
| COHEN CHARLES | Director | Mar 13, 2017 | Sale | $21.82 | 10,000 | 218,200 | 238,180 | Mar 14, 2017, 08:12 PM |
| MARCHESI VINCENT T | Director | Mar 10, 2017 | Option Exercise | $3.13 | 40,000 | 125,200 | 160,070 | Mar 10, 2017, 07:37 PM |
| MARCHESI VINCENT T | Director | Mar 10, 2017 | Sale | $21.98 | 40,000 | 879,200 | 120,070 | Mar 10, 2017, 07:37 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Mar 03, 2017 | Option Exercise | $7.27 | 100,000 | 727,000 | 346,617 | Mar 07, 2017, 08:00 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Mar 03, 2017 | Sale | $23.04 | 100,000 | 2,303,678 | 309,618 | Mar 07, 2017, 08:00 PM |
| MORRISSEY MICHAEL | President and CEO | Mar 06, 2017 | Option Exercise | $9.91 | 100,000 | 991,000 | 160,000 | Mar 07, 2017, 07:56 PM |
| MORRISSEY MICHAEL | President and CEO | Mar 03, 2017 | Option Exercise | $9.91 | 100,000 | 991,000 | 160,000 | Mar 07, 2017, 07:56 PM |
| MORRISSEY MICHAEL | President and CEO | Mar 06, 2017 | Sale | $22.61 | 100,000 | 2,261,000 | 60,000 | Mar 07, 2017, 07:56 PM |
| MORRISSEY MICHAEL | President and CEO | Mar 03, 2017 | Sale | $22.83 | 100,000 | 2,283,000 | 60,000 | Mar 07, 2017, 07:56 PM |
| Haley Patrick J. | Sr. Vice President, Commercial | Mar 03, 2017 | Sale | $23.04 | 2,500 | 57,600 | 107,193 | Mar 07, 2017, 07:45 PM |
| Senner Christopher J. | EVP and CFO | Mar 03, 2017 | Sale | $22.80 | 11,000 | 250,800 | 100,398 | Mar 03, 2017, 08:20 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Mar 01, 2017 | Option Exercise | $7.36 | 45,000 | 331,350 | 118,600 | Mar 03, 2017, 08:18 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Mar 01, 2017 | Sale | $22.19 | 45,000 | 998,550 | 73,600 | Mar 03, 2017, 08:18 PM |
| POSTE GEORGE | Director | Mar 01, 2017 | Option Exercise | $10.53 | 8,850 | 93,190 | 86,405 | Mar 03, 2017, 08:17 PM |
| POSTE GEORGE | Director | Mar 02, 2017 | Option Exercise | $4.51 | 67,400 | 303,659 | 144,955 | Mar 03, 2017, 08:17 PM |
| POSTE GEORGE | Director | Mar 01, 2017 | Sale | $22.18 | 8,850 | 196,293 | 77,555 | Mar 03, 2017, 08:17 PM |
| POSTE GEORGE | Director | Mar 02, 2017 | Sale | $22.58 | 67,400 | 1,521,892 | 77,555 | Mar 03, 2017, 08:17 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Feb 01, 2017 | Option Exercise | $6.92 | 70,000 | 484,300 | 143,600 | Feb 03, 2017, 07:55 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Feb 01, 2017 | Sale | $18.65 | 70,000 | 1,305,500 | 73,600 | Feb 03, 2017, 07:55 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jan 03, 2017 | Option Exercise | $5.74 | 70,000 | 401,800 | 143,600 | Jan 05, 2017, 08:25 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Jan 03, 2017 | Sale | $14.65 | 70,000 | 1,025,636 | 76,000 | Jan 05, 2017, 08:25 PM |
| FELDBAUM CARL B | Director | Dec 16, 2016 | Option Exercise | $10.41 | 25,000 | 260,250 | 73,721 | Dec 16, 2016, 07:29 PM |
| FELDBAUM CARL B | Director | Dec 16, 2016 | Sale | $17.03 | 25,000 | 425,750 | 48,721 | Dec 16, 2016, 07:29 PM |
| Garber Alan M | Director | Dec 09, 2016 | Option Exercise | $10.53 | 10,000 | 105,300 | 69,161 | Dec 09, 2016, 08:02 PM |
| Garber Alan M | Director | Dec 09, 2016 | Sale | $16.90 | 7,832 | 132,361 | 61,329 | Dec 09, 2016, 08:02 PM |
| SCANGOS GEORGE A | Director | Dec 07, 2016 | Option Exercise | $8.99 | 356 | 3,200 | 1,463,824 | Dec 07, 2016, 07:03 PM |
| SCANGOS GEORGE A | Director | Dec 05, 2016 | Option Exercise | $8.99 | 357,976 | 3,218,204 | 1,668,186 | Dec 07, 2016, 07:03 PM |
| SCANGOS GEORGE A | Director | Dec 07, 2016 | Sale | $17.90 | 176 | 3,150 | 1,463,648 | Dec 07, 2016, 07:03 PM |
| SCANGOS GEORGE A | Director | Dec 05, 2016 | Sale | $17.81 | 204,718 | 3,646,027 | 1,463,468 | Dec 07, 2016, 07:03 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Dec 01, 2016 | Option Exercise | $5.27 | 70,000 | 368,800 | 143,600 | Dec 02, 2016, 07:14 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Dec 01, 2016 | Sale | $16.66 | 70,000 | 1,166,200 | 73,600 | Dec 02, 2016, 07:14 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Dec 01, 2016 | Option Exercise | $8.99 | 22,000 | 197,780 | 180,053 | Dec 02, 2016, 07:13 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Dec 01, 2016 | Sale | $16.73 | 22,000 | 368,060 | 158,053 | Dec 02, 2016, 07:13 PM |
| Senner Christopher J. | EVP and CFO | Jul 15, 2016 | Option Exercise | $8.44 | 46,751 | 394,578 | 105,976 | Nov 23, 2016, 04:16 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 09, 2016 | Option Exercise | $8.99 | 200,000 | 1,798,000 | 260,000 | Nov 14, 2016, 07:37 PM |
| MORRISSEY MICHAEL | President and CEO | Nov 09, 2016 | Sale | $15.00 | 200,000 | 3,000,000 | 60,000 | Nov 14, 2016, 07:37 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Nov 09, 2016 | Option Exercise | $8.99 | 22,000 | 197,780 | 180,053 | Nov 14, 2016, 07:36 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Nov 09, 2016 | Sale | $15.00 | 22,000 | 330,000 | 158,053 | Nov 14, 2016, 07:36 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Nov 09, 2016 | Option Exercise | $5.17 | 70,000 | 362,000 | 143,600 | Nov 14, 2016, 07:34 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Nov 09, 2016 | Sale | $13.15 | 70,000 | 920,500 | 73,600 | Nov 14, 2016, 07:34 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Aug 31, 2016 | Option Exercise | $9.73 | 132,662 | 1,290,801 | 267,596 | Sep 02, 2016, 04:34 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Aug 31, 2016 | Sale | $10.98 | 131,155 | 1,440,082 | 136,441 | Sep 02, 2016, 04:34 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Aug 04, 2016 | Option Exercise | $9.73 | 42,338 | 411,949 | 174,354 | Aug 05, 2016, 07:29 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Aug 04, 2016 | Sale | $11.00 | 42,338 | 465,718 | 132,016 | Aug 05, 2016, 07:29 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Jun 01, 2016 | Option Exercise | $1.70 | 200,000 | 340,000 | 230,367 | Jun 02, 2016, 06:37 PM |
| WILLSEY LANCE | Director | May 11, 2016 | Buy | $4.95 | 20,000 | 99,000 | 568,273 | May 11, 2016, 05:23 PM |
| WILLSEY LANCE | Director | May 09, 2016 | Buy | $4.97 | 40,000 | 198,900 | 548,273 | May 11, 2016, 05:23 PM |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | Feb 11, 2016 | Option Exercise | $4.20 | 25,232 | 105,974 | 132,016 | Feb 16, 2016, 08:52 PM |
| Lamb Peter | EVP, Scientific Strategy & CSO | Feb 11, 2016 | Option Exercise | $4.20 | 25,454 | 106,907 | 57,350 | Feb 16, 2016, 08:51 PM |
| Hessekiel Jeffrey | EVP and General Counsel | Feb 11, 2016 | Option Exercise | $4.20 | 19,535 | 82,047 | 30,367 | Feb 16, 2016, 08:50 PM |
| Senner Christopher J. | EVP and CFO | Feb 11, 2016 | Option Exercise | $4.20 | 20,845 | 87,549 | 132,727 | Feb 16, 2016, 08:49 PM |
| MORRISSEY MICHAEL | President and CEO | Feb 11, 2016 | Option Exercise | $4.20 | 43,149 | 181,226 | 71,137 | Feb 16, 2016, 08:48 PM |
| WILLSEY LANCE | Director | Dec 11, 2015 | Buy | $4.78 | 50,000 | 239,000 | 494,975 | Dec 11, 2015, 07:43 PM |
| WILLSEY LANCE | Director | Dec 10, 2015 | Buy | $4.99 | 50,000 | 249,550 | 444,975 | Dec 11, 2015, 07:43 PM |
| Lamb Peter | EVP, Discovery Research & CSO | Oct 16, 2015 | Option Exercise | $5.63 | 51,549 | 290,221 | 88,022 | Oct 19, 2015, 05:08 PM |
| Lamb Peter | EVP, Discovery Research & CSO | Oct 16, 2015 | Sale | $5.80 | 51,549 | 298,984 | 36,473 | Oct 19, 2015, 05:08 PM |
| Lamb Peter | EVP, Discovery Research & CSO | Oct 13, 2015 | Option Exercise | $5.63 | 600 | 3,378 | 37,073 | Oct 14, 2015, 05:05 PM |
| Lamb Peter | EVP, Discovery Research & CSO | Oct 12, 2015 | Option Exercise | $5.63 | 300,276 | 1,690,554 | 336,749 | Oct 14, 2015, 05:05 PM |
| Lamb Peter | EVP, Discovery Research & CSO | Oct 13, 2015 | Sale | $5.80 | 600 | 3,480 | 36,473 | Oct 14, 2015, 05:05 PM |
| Lamb Peter | EVP, Discovery Research & CSO | Oct 12, 2015 | Sale | $5.84 | 300,276 | 1,753,312 | 36,473 | Oct 14, 2015, 05:05 PM |
| MARCHESI VINCENT T | Director | Sep 17, 2014 | Buy | $1.71 | 20,000 | 34,199 | 45,000 | Sep 19, 2014, 05:05 PM |
| WILLSEY LANCE | Director | Aug 29, 2013 | Buy | $5.15 | 10,000 | 51,454 | 333,700 | Aug 30, 2013, 06:44 PM |
| MARCHESI VINCENT T | Director | Dec 20, 2012 | Buy | $4.68 | 4,000 | 18,720 | 25,000 | Dec 20, 2012, 07:11 PM |
| MARCHESI VINCENT T | Director | Dec 19, 2012 | Buy | $4.67 | 1,500 | 7,005 | 21,000 | Dec 19, 2012, 07:49 PM |
| MARCHESI VINCENT T | Director | Dec 18, 2012 | Buy | $4.82 | 1,500 | 7,230 | 19,500 | Dec 19, 2012, 07:49 PM |
| MARCHESI VINCENT T | Director | Dec 17, 2012 | Buy | $4.70 | 3,000 | 14,093 | 18,000 | Dec 19, 2012, 07:49 PM |
| Schwab Gisela | EVP and Chief Medical Officer | Dec 10, 2012 | Buy | $4.39 | 25,000 | 109,750 | 56,874 | Dec 10, 2012, 08:25 PM |
| MARCHESI VINCENT T | Director | Jun 14, 2012 | Sale | $5.13 | 7,000 | 35,911 | 21,900 | Jun 15, 2012, 05:03 PM |
| RIVERA LUPE M | EVP, Operations | Dec 17, 2010 | Option Exercise | $5.45 | 29,427 | 160,317 | 25,000 | Dec 17, 2010, 08:52 PM |
| RIVERA LUPE M | EVP, Operations | Dec 17, 2010 | Sale | $8.50 | 29,427 | 250,130 | 0 | Dec 17, 2010, 08:52 PM |
| RIVERA LUPE M | EVP, Operations | Dec 15, 2010 | Option Exercise | $5.63 | 50,000 | 281,500 | 25,000 | Dec 16, 2010, 09:09 PM |
| RIVERA LUPE M | EVP, Operations | Dec 14, 2010 | Option Exercise | $5.63 | 25,000 | 140,750 | 11,750 | Dec 16, 2010, 09:09 PM |
| RIVERA LUPE M | EVP, Operations | Dec 15, 2010 | Sale | $7.75 | 50,000 | 387,500 | 0 | Dec 16, 2010, 09:09 PM |
| RIVERA LUPE M | EVP, Operations | Dec 14, 2010 | Sale | $7.00 | 25,000 | 175,000 | 0 | Dec 16, 2010, 09:09 PM |
| Schwab Gisela | EVP & Chief Medical Officer | Dec 09, 2010 | Sale | $6.50 | 4,112 | 26,728 | 7,322 | Dec 10, 2010, 07:54 PM |
| WILLSEY LANCE | Director | Sep 07, 2010 | Buy | $3.66 | 21,078 | 77,171 | 323,700 | Sep 08, 2010, 04:53 PM |
| WILLSEY LANCE | Director | Sep 03, 2010 | Buy | $3.52 | 15,122 | 53,299 | 302,622 | Sep 08, 2010, 04:53 PM |
| WILLSEY LANCE | Director | Aug 30, 2010 | Buy | $3.18 | 71,300 | 226,515 | 287,500 | Sep 01, 2010, 07:37 PM |
| WILLSEY LANCE | Director | Aug 27, 2010 | Buy | $3.26 | 28,700 | 93,539 | 216,200 | Aug 31, 2010, 07:55 PM |
| KARBE FRANK | EVP & CFO | Aug 24, 2010 | Buy | $2.98 | 16,500 | 49,165 | 60,110 | Aug 25, 2010, 08:51 PM |
| PAPADOPOULOS STELIOS | Director | Aug 24, 2010 | Buy | $3.05 | 200,000 | 610,197 | 1,143,956 | Aug 25, 2010, 08:48 PM |
| WILLSEY LANCE | Director | Aug 16, 2010 | Buy | $2.90 | 53,600 | 155,350 | 187,500 | Aug 17, 2010, 08:55 PM |
| WILLSEY LANCE | Director | Aug 13, 2010 | Buy | $2.97 | 46,400 | 137,690 | 133,900 | Aug 17, 2010, 08:55 PM |
| MORRISSEY MICHAEL | President & CEO | Aug 13, 2010 | Buy | $2.94 | 30,000 | 88,344 | 72,500 | Aug 17, 2010, 08:42 PM |
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| Owner | Relationship | Date | Value($) |
| Garber Alan M | Director | 03/21/2024 | 459,719 |
| Garber Alan M | Director | 03/21/2024 | 461,112 |
| Haley Patrick J. | EVP, Commercial | 02/23/2024 | 1,008,579 |
| JOHNSON DAVID EDWARD | Director | 02/21/2024 | 3,932,734 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 02/15/2024 | 216,746 |
| MORRISSEY MICHAEL | President and CEO | 01/11/2024 | 1,456,571 |
| Senner Christopher J. | EVP and CFO | 01/11/2024 | 499,765 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 01/11/2024 | 298,574 |
| Haley Patrick J. | EVP, Commercial | 01/11/2024 | 311,193 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 01/11/2024 | 265,313 |
| Haley Patrick J. | EVP, Commercial | 12/14/2023 | 814,500 |
| Haley Patrick J. | EVP, Commercial | 12/14/2023 | 1,167,500 |
| Haley Patrick J. | EVP, Commercial | 12/12/2023 | 318,353 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 12/13/2023 | 575,250 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 11/30/2023 | 550,250 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 12/04/2023 | 551,500 |
| JOHNSON DAVID EDWARD | Director | 11/27/2023 | 2,602,039 |
| JOHNSON DAVID EDWARD | Director | 11/27/2023 | 2,602,039 |
| MORRISSEY MICHAEL | President and CEO | 09/06/2023 | 1,037,960 |
| Senner Christopher J. | EVP and CFO | 09/06/2023 | 381,864 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 09/06/2023 | 279,711 |
| Haley Patrick J. | EVP, Commercial | 09/06/2023 | 319,664 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 09/06/2023 | 319,664 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 08/30/2023 | 103,362 |
| MORRISSEY MICHAEL | President and CEO | 08/28/2023 | 6,737,818 |
| MORRISSEY MICHAEL | President and CEO | 08/28/2023 | 5,511,600 |
| MORRISSEY MICHAEL | President and CEO | 08/15/2023 | 501,269 |
| Senner Christopher J. | EVP and CFO | 08/15/2023 | 173,672 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 08/15/2023 | 154,377 |
| Haley Patrick J. | EVP, Commercial | 08/15/2023 | 154,377 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 08/15/2023 | 135,083 |
| Senner Christopher J. | EVP and CFO | 08/03/2023 | 884,400 |
| Senner Christopher J. | EVP and CFO | 08/04/2023 | 884,400 |
| Senner Christopher J. | EVP and CFO | 08/04/2023 | 1,240,800 |
| Senner Christopher J. | EVP and CFO | 08/03/2023 | 1,230,600 |
| Haley Patrick J. | EVP, Commercial | 08/03/2023 | 631,531 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 08/01/2023 | 821,165 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 08/01/2023 | 1,093,587 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 05/15/2023 | 229,527 |
| Senner Christopher J. | EVP and CFO | 05/15/2023 | 353,794 |
| MORRISSEY MICHAEL | President and CEO | 05/15/2023 | 642,875 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 05/15/2023 | 201,160 |
| Haley Patrick J. | EVP, Commercial | 05/15/2023 | 346,487 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 04/05/2023 | 205,328 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 04/05/2023 | 778,989 |
| WYSZOMIERSKI JACK L | Director | 03/10/2023 | 252,000 |
| WYSZOMIERSKI JACK L | Director | 03/10/2023 | 254,133 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 03/01/2023 | 410,656 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 03/01/2023 | 1,333,742 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 02/28/2023 | 1,215,903 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 02/27/2023 | 147 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 02/28/2023 | 1,443,575 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 02/27/2023 | 175 |
| Garber Alan M | Director | 02/21/2023 | 252,000 |
| Garber Alan M | Director | 02/21/2023 | 699,600 |
| MORRISSEY MICHAEL | President and CEO | 02/15/2023 | 208,318 |
| Haley Patrick J. | EVP, Commercial | 02/15/2023 | 28,132 |
| Senner Christopher J. | EVP and CFO | 02/15/2023 | 95,426 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 02/15/2023 | 34,876 |
| Aftab Dana | CSO/EVP Disc & Trans Research | 02/15/2023 | 27,644 |
| Goodman Vicki L | EVP, Prod Dev & Med Aff &CMO | 02/15/2023 | 312,766 |
| FELDBAUM CARL B | Director | 02/09/2023 | 252,000 |
| FELDBAUM CARL B | Director | 02/09/2023 | 711,200 |
| Haley Patrick J. | EVP, Commercial | 02/06/2023 | 105,000 |
| Haley Patrick J. | EVP, Commercial | 02/06/2023 | 434,250 |
| MORRISSEY MICHAEL | President and CEO | 01/24/2023 | 1,076,424 |
| MORRISSEY MICHAEL | President and CEO | 01/24/2023 | 420,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 12/15/2022 | 84,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 12/15/2022 | 317,600 |
| POSTE GEORGE | Director | 11/29/2022 | 252,000 |
| POSTE GEORGE | Director | 11/29/2022 | 667,200 |
| Haley Patrick J. | EVP, Commercial | 11/15/2022 | 119,928 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 11/15/2022 | 119,928 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 05/16/2022 | 361,260 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 05/17/2021 | 457,020 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 11/15/2022 | 119,928 |
| MORRISSEY MICHAEL | President and CEO | 11/15/2022 | 389,410 |
| Senner Christopher J. | EVP and CFO | 11/15/2022 | 134,917 |
| Haley Patrick J. | EVP, Commercial | 09/12/2022 | 248,400 |
| Haley Patrick J. | EVP, Commercial | 09/12/2022 | 717,600 |
| Senner Christopher J. | EVP and CFO | 08/11/2022 | 2,939,632 |
| Senner Christopher J. | EVP and CFO | 08/11/2022 | 1,397,250 |
| MORRISSEY MICHAEL | President and CEO | 08/03/2022 | 500,803 |
| Senner Christopher J. | EVP and CFO | 08/03/2022 | 173,510 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 08/03/2022 | 154,234 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 08/03/2022 | 154,234 |
| Haley Patrick J. | EVP, Commercial | 08/03/2022 | 154,234 |
| Haley Patrick J. | EVP, Commercial | 05/27/2022 | 342,567 |
| Haley Patrick J. | EVP, Commercial | 05/15/2022 | 235,398 |
| Senner Christopher J. | EVP and CFO | 05/15/2022 | 169,556 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 05/15/2022 | 122,950 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 05/15/2022 | 107,408 |
| WILLSEY LANCE | Director | 05/12/2022 | 125,200 |
| WILLSEY LANCE | Director | 05/12/2022 | 786,000 |
| WYSZOMIERSKI JACK L | Director | 04/04/2022 | 125,200 |
| WYSZOMIERSKI JACK L | Director | 04/04/2022 | 154,008 |
| Haley Patrick J. | EVP, Commercial | 03/31/2022 | 62,100 |
| Haley Patrick J. | EVP, Commercial | 04/01/2022 | 62,100 |
| Haley Patrick J. | EVP, Commercial | 04/01/2022 | 230,000 |
| Haley Patrick J. | EVP, Commercial | 03/31/2022 | 224,300 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 03/29/2022 | 292,226 |
| Hessekiel Jeffrey | EVP, General Counsel & Sec | 03/28/2022 | 103,774 |
| Garber Alan M | Director | 03/01/2022 | 125,200 |
| Garber Alan M | Director | 03/01/2022 | 447,321 |
| Hessekiel Jeffrey | EVP and General Counsel | 02/24/2022 | 360,000 |
| Haley Patrick J. | EVP, Commercial | 02/25/2022 | 610,078 |
| PAPADOPOULOS STELIOS | Director | 02/22/2022 | 1,653,113 |
| FELDBAUM CARL B | Director | 02/22/2022 | 62,600 |
| FELDBAUM CARL B | Director | 02/22/2022 | 389,800 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 02/15/2022 | 375,090 |
| Hessekiel Jeffrey | EVP and General Counsel | 02/15/2022 | 227,281 |
| MORRISSEY MICHAEL | President and CEO | 02/15/2022 | 1,211,083 |
| Senner Christopher J. | EVP and CFO | 02/15/2022 | 340,699 |
| Haley Patrick J. | EVP, Commercial | 02/15/2022 | 288,647 |
| Haley Patrick J. | EVP, Commercial | 02/03/2022 | 114,000 |
| Haley Patrick J. | EVP, Commercial | 02/03/2022 | 1,074,600 |
| Goodman Vicki L | EVP, Prod Dev & Med Aff &CMO | 01/04/2022 | 146,017 |
| MORRISSEY MICHAEL | President and CEO | 12/15/2021 | 208,012 |
| Haley Patrick J. | EVP, Commercial | 12/15/2021 | 26,452 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 12/15/2021 | 78,982 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 12/15/2021 | 294,975 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 12/15/2021 | 828,400 |
| Senner Christopher J. | EVP and CFO | 12/15/2021 | 87,227 |
| Hessekiel Jeffrey | EVP and General Counsel | 12/15/2021 | 44,557 |
| Haley Patrick J. | EVP, Commercial | 11/24/2021 | 297,321 |
| FELDBAUM CARL B | Director | 11/19/2021 | 62,600 |
| FELDBAUM CARL B | Director | 11/19/2021 | 352,400 |
| Haley Patrick J. | EVP, Commercial | 11/15/2021 | 895,769 |
| Senner Christopher J. | EVP and CFO | 11/15/2021 | 1,044,605 |
| Hessekiel Jeffrey | EVP and General Counsel | 11/15/2021 | 988,459 |
| MORRISSEY MICHAEL | President and CEO | 11/15/2021 | 3,507,418 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 11/15/2021 | 1,125,150 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 11/15/2021 | 294,975 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 11/15/2021 | 859,275 |
| Hessekiel Jeffrey | EVP and General Counsel | 11/01/2021 | 112,728 |
| MORRISSEY MICHAEL | President and CEO | 10/22/2021 | 527,854 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 10/15/2021 | 294,975 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 10/15/2021 | 1,041,200 |
| Hessekiel Jeffrey | EVP and General Counsel | 10/15/2021 | 283,684 |
| Senner Christopher J. | EVP and CFO | 09/30/2021 | 176,861 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/30/2021 | 156,644 |
| Haley Patrick J. | EVP, Commercial | 09/30/2021 | 111,732 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 09/30/2021 | 148,062 |
| Senner Christopher J. | EVP and CFO | 09/21/2021 | 1,119,309 |
| Senner Christopher J. | EVP and CFO | 09/21/2021 | 329,400 |
| Haley Patrick J. | EVP, Commercial | 09/16/2021 | 42,500 |
| Haley Patrick J. | EVP, Commercial | 09/16/2021 | 509,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 09/15/2021 | 294,975 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 09/15/2021 | 971,850 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 08/16/2021 | 104,500 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 08/16/2021 | 1,014,200 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 07/26/2021 | 168,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 07/21/2021 | 147,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 07/15/2021 | 114,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 07/15/2021 | 1,048,200 |
| COHEN CHARLES | Director | 07/06/2021 | 377,200 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/17/2021 | 114,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/17/2021 | 1,330,800 |
| Freire Maria C | Director | 05/11/2021 | 206,958 |
| POSTE GEORGE | Director | 05/14/2021 | 1,018,826 |
| MORRISSEY MICHAEL | President and CEO | 05/12/2021 | 761,794 |
| MORRISSEY MICHAEL | President and CEO | 05/12/2021 | 210,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 05/13/2021 | 190,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 05/13/2021 | 2,538,000 |
| PAPADOPOULOS STELIOS | Director | 05/11/2021 | 512,400 |
| PAPADOPOULOS STELIOS | Director | 05/11/2021 | 518,794 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 04/26/2021 | 85,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 04/26/2021 | 1,250,000 |
| Haley Patrick J. | EVP, Commercial | 04/26/2021 | 191,855 |
| Hessekiel Jeffrey | EVP and General Counsel | 04/26/2021 | 450,540 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 04/01/2021 | 102,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 04/01/2021 | 1,377,600 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 04/01/2021 | 85,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 04/01/2021 | 1,150,000 |
| WYSZOMIERSKI JACK L | Director | 03/29/2021 | 135,200 |
| WYSZOMIERSKI JACK L | Director | 03/29/2021 | 140,821 |
| Garber Alan M | Director | 03/15/2021 | 135,200 |
| Garber Alan M | Director | 03/15/2021 | 944,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 03/01/2021 | 110,500 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 03/01/2021 | 1,437,150 |
| COHEN CHARLES | Director | 02/24/2021 | 135,200 |
| COHEN CHARLES | Director | 02/24/2021 | 907,600 |
| POSTE GEORGE | Director | 02/22/2021 | 135,200 |
| MARCHESI VINCENT T | Director | 02/22/2021 | 537,122 |
| WILLSEY LANCE | Director | 02/23/2021 | 135,200 |
| WILLSEY LANCE | Director | 02/23/2021 | 877,136 |
| WILLSEY LANCE | Director | 02/16/2021 | 1,095,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/17/2021 | 85,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/18/2021 | 85,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/18/2021 | 1,117,500 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/17/2021 | 1,125,000 |
| Haley Patrick J. | EVP, Commercial | 02/15/2021 | 30,674 |
| Haley Patrick J. | EVP, Commercial | 02/12/2021 | 970,650 |
| Senner Christopher J. | EVP and CFO | 02/15/2021 | 89,941 |
| Hessekiel Jeffrey | EVP and General Counsel | 02/15/2021 | 36,918 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/15/2021 | 62,619 |
| MORRISSEY MICHAEL | President and CEO | 02/15/2021 | 214,477 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 02/15/2021 | 81,461 |
| FELDBAUM CARL B | Director | 02/16/2021 | 67,600 |
| FELDBAUM CARL B | Director | 02/16/2021 | 439,200 |
| MORRISSEY MICHAEL | President and CEO | 02/03/2021 | 1,470,686 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 02/03/2021 | 451,132 |
| Hessekiel Jeffrey | EVP and General Counsel | 02/03/2021 | 346,634 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/03/2021 | 337,994 |
| Haley Patrick J. | EVP, Commercial | 02/03/2021 | 254,184 |
| Senner Christopher J. | EVP and CFO | 02/03/2021 | 410,727 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 02/01/2021 | 110,500 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 02/01/2021 | 1,435,200 |
| Senner Christopher J. | EVP and CFO | 01/12/2021 | 109,800 |
| Senner Christopher J. | EVP and CFO | 01/12/2021 | 750,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 01/04/2021 | 110,500 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 01/04/2021 | 1,320,800 |
| Hessekiel Jeffrey | EVP and General Counsel | 01/04/2021 | 256,100 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 12/18/2020 | 110,500 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 12/18/2020 | 1,300,650 |
| WILLSEY LANCE | Director | 12/04/2020 | 617,746 |
| MARCHESI VINCENT T | Director | 11/24/2020 | 232,823 |
| MARCHESI VINCENT T | Director | 11/24/2020 | 740,074 |
| MORRISSEY MICHAEL | President and CEO | 11/15/2020 | 503,073 |
| Haley Patrick J. | EVP, Commercial | 11/15/2020 | 210,591 |
| Senner Christopher J. | EVP and CFO | 11/15/2020 | 274,116 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 11/15/2020 | 228,030 |
| Hessekiel Jeffrey | EVP and General Counsel | 11/15/2020 | 206,862 |
| Hessekiel Jeffrey | EVP and General Counsel | 11/15/2020 | 218,100 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 11/15/2020 | 301,452 |
| WYSZOMIERSKI JACK L | Director | 11/10/2020 | 363,185 |
| WYSZOMIERSKI JACK L | Director | 11/10/2020 | 700,740 |
| MORRISSEY MICHAEL | President and CEO | 10/22/2020 | 3,859,706 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 10/22/2020 | 1,203,571 |
| Haley Patrick J. | EVP, Commercial | 10/22/2020 | 962,769 |
| Hessekiel Jeffrey | EVP and General Counsel | 10/22/2020 | 1,018,508 |
| Senner Christopher J. | EVP and CFO | 10/22/2020 | 1,022,387 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 10/22/2020 | 1,155,349 |
| Hessekiel Jeffrey | EVP and General Counsel | 10/21/2020 | 288,924 |
| Hessekiel Jeffrey | EVP and General Counsel | 10/21/2020 | 872,337 |
| Senner Christopher J. | EVP and CFO | 10/08/2020 | 36,600 |
| Senner Christopher J. | EVP and CFO | 10/08/2020 | 250,000 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/22/2020 | 74,576 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/22/2020 | 268,144 |
| Haley Patrick J. | EVP, Commercial | 09/21/2020 | 27,238 |
| Haley Patrick J. | EVP, Commercial | 09/21/2020 | 122,101 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/16/2020 | 145,400 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/16/2020 | 522,200 |
| Senner Christopher J. | EVP and CFO | 09/15/2020 | 73,200 |
| Senner Christopher J. | EVP and CFO | 09/15/2020 | 500,000 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/08/2020 | 3,327,393 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/08/2020 | 1,293,315 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 09/02/2020 | 50,130 |
| Haley Patrick J. | EVP, Commercial | 09/02/2020 | 24,083 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/02/2020 | 28,291 |
| Senner Christopher J. | EVP and CFO | 09/02/2020 | 55,374 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 09/02/2020 | 54,317 |
| MORRISSEY MICHAEL | President and CEO | 09/02/2020 | 132,026 |
| COHEN CHARLES | Director | 09/01/2020 | 671,605 |
| POSTE GEORGE | Director | 08/14/2020 | 172,633 |
| MORRISSEY MICHAEL | President and CEO | 07/20/2020 | 1,641,907 |
| MORRISSEY MICHAEL | President and CEO | 07/20/2020 | 621,000 |
| Haley Patrick J. | EVP, Commercial | 07/20/2020 | 79,909 |
| MORRISSEY MICHAEL | President and CEO | 07/10/2020 | 1,607,159 |
| MORRISSEY MICHAEL | President and CEO | 07/10/2020 | 621,000 |
| MORRISSEY MICHAEL | President and CEO | 06/19/2020 | 1,567,130 |
| MORRISSEY MICHAEL | President and CEO | 06/19/2020 | 621,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/08/2020 | 143,260 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/08/2020 | 586,560 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 06/04/2020 | 170,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 06/04/2020 | 2,296,000 |
| MORRISSEY MICHAEL | President and CEO | 05/29/2020 | 1,595,030 |
| MORRISSEY MICHAEL | President and CEO | 05/29/2020 | 621,000 |
| MARCHESI VINCENT T | Director | 05/21/2020 | 232,800 |
| MARCHESI VINCENT T | Director | 05/21/2020 | 985,600 |
| Garber Alan M | Director | 05/22/2020 | 881,831 |
| Haley Patrick J. | EVP, Commercial | 05/20/2020 | 78,743 |
| WILLSEY LANCE | Director | 05/18/2020 | 137,400 |
| WILLSEY LANCE | Director | 05/18/2020 | 787,800 |
| SCANGOS GEORGE A | Director | 05/18/2020 | 1,947,000 |
| MORRISSEY MICHAEL | President and CEO | 05/15/2020 | 1,650,314 |
| MORRISSEY MICHAEL | President and CEO | 05/15/2020 | 621,000 |
| SCANGOS GEORGE A | Director | 05/15/2020 | 263,613 |
| Hessekiel Jeffrey | EVP and General Counsel | 05/13/2020 | 368,104 |
| Hessekiel Jeffrey | EVP and General Counsel | 05/13/2020 | 42,500 |
| WILLSEY LANCE | Director | 05/14/2020 | 88,800 |
| WILLSEY LANCE | Director | 05/14/2020 | 378,900 |
| PAPADOPOULOS STELIOS | Director | 05/13/2020 | 703,004 |
| MARCHESI VINCENT T | Director | 05/11/2020 | 137,400 |
| MARCHESI VINCENT T | Director | 05/11/2020 | 789,000 |
| Hessekiel Jeffrey | EVP and General Counsel | 05/08/2020 | 47,500 |
| Hessekiel Jeffrey | EVP and General Counsel | 05/07/2020 | 57,000 |
| Hessekiel Jeffrey | EVP and General Counsel | 05/11/2020 | 72,211 |
| Hessekiel Jeffrey | EVP and General Counsel | 05/07/2020 | 768,300 |
| Hessekiel Jeffrey | EVP and General Counsel | 05/11/2020 | 1,029,583 |
| Hessekiel Jeffrey | EVP and General Counsel | 05/08/2020 | 651,000 |
| Senner Christopher J. | EVP and CFO | 05/07/2020 | 78,386 |
| Senner Christopher J. | EVP and CFO | 05/08/2020 | 287,614 |
| Senner Christopher J. | EVP and CFO | 05/08/2020 | 2,028,227 |
| Senner Christopher J. | EVP and CFO | 05/07/2020 | 552,559 |
| PAPADOPOULOS STELIOS | Director | 05/08/2020 | 226,200 |
| PAPADOPOULOS STELIOS | Director | 05/08/2020 | 1,162,800 |
| Haley Patrick J. | EVP, Commercial | 05/08/2020 | 37,620 |
| Haley Patrick J. | EVP, Commercial | 05/08/2020 | 552,971 |
| FELDBAUM CARL B | Director | 05/07/2020 | 134,798 |
| FELDBAUM CARL B | Director | 05/07/2020 | 789,281 |
| POSTE GEORGE | Director | 05/07/2020 | 174,600 |
| POSTE GEORGE | Director | 05/07/2020 | 768,300 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 05/07/2020 | 275,500 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 05/07/2020 | 1,277,000 |
| MORRISSEY MICHAEL | President and CEO | 05/06/2020 | 4,163,451 |
| MORRISSEY MICHAEL | President and CEO | 05/06/2020 | 484,983 |
| MORRISSEY MICHAEL | President and CEO | 04/27/2020 | 4,336,366 |
| MORRISSEY MICHAEL | President and CEO | 04/27/2020 | 484,500 |
| MORRISSEY MICHAEL | President and CEO | 04/23/2020 | 4,123,213 |
| MORRISSEY MICHAEL | President and CEO | 04/23/2020 | 1,377,500 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 04/23/2020 | 170,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 04/23/2020 | 2,600,000 |
| SCANGOS GEORGE A | Director | 04/24/2020 | 393,600 |
| SCANGOS GEORGE A | Director | 04/23/2020 | 2,598,635 |
| Haley Patrick J. | EVP, Commercial | 04/23/2020 | 8,500 |
| Haley Patrick J. | EVP, Commercial | 04/23/2020 | 130,000 |
| MORRISSEY MICHAEL | President and CEO | 04/21/2020 | 3,418,776 |
| MORRISSEY MICHAEL | President and CEO | 04/20/2020 | 3,605,877 |
| MORRISSEY MICHAEL | President and CEO | 04/20/2020 | 1,322,400 |
| MORRISSEY MICHAEL | President and CEO | 04/21/2020 | 1,212,200 |
| SCANGOS GEORGE A | Director | 04/22/2020 | 105,210 |
| SCANGOS GEORGE A | Director | 04/21/2020 | 145,232 |
| SCANGOS GEORGE A | Director | 04/20/2020 | 1,194,637 |
| Haley Patrick J. | EVP, Commercial | 04/20/2020 | 8,500 |
| Haley Patrick J. | EVP, Commercial | 04/20/2020 | 120,000 |
| SCANGOS GEORGE A | Director | 04/15/2020 | 457,750 |
| SCANGOS GEORGE A | Director | 04/08/2020 | 129,643 |
| SCANGOS GEORGE A | Director | 04/07/2020 | 299,939 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 04/06/2020 | 275,500 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 04/06/2020 | 863,000 |
| WYSZOMIERSKI JACK L | Director | 04/03/2020 | 226,200 |
| WYSZOMIERSKI JACK L | Director | 04/03/2020 | 229,461 |
| SCANGOS GEORGE A | Director | 03/31/2020 | 27,090 |
| Haley Patrick J. | EVP, Commercial | 03/20/2020 | 66,368 |
| MORRISSEY MICHAEL | President and CEO | 03/04/2020 | 654,063 |
| MORRISSEY MICHAEL | President and CEO | 03/04/2020 | 275,500 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 03/04/2020 | 170,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 03/04/2020 | 1,940,000 |
| FELDBAUM CARL B | Director | 03/03/2020 | 213,720 |
| FELDBAUM CARL B | Director | 03/03/2020 | 716,013 |
| COHEN CHARLES | Director | 02/28/2020 | 226,200 |
| MORRISSEY MICHAEL | President and CEO | 02/26/2020 | 137,750 |
| MORRISSEY MICHAEL | President and CEO | 02/26/2020 | 472,850 |
| SCANGOS GEORGE A | Director | 02/18/2020 | 1,036,500 |
| Haley Patrick J. | EVP, Commercial | 02/19/2020 | 110,000 |
| MORRISSEY MICHAEL | President and CEO | 02/19/2020 | 543,750 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/19/2020 | 220,400 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/19/2020 | 860,000 |
| MORRISSEY MICHAEL | President and CEO | 02/13/2020 | 137,750 |
| MORRISSEY MICHAEL | President and CEO | 02/13/2020 | 502,750 |
| Garber Alan M | Director | 02/14/2020 | 262,750 |
| SCANGOS GEORGE A | Director | 02/11/2020 | 80,560 |
| SCANGOS GEORGE A | Director | 02/12/2020 | 420,420 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/07/2020 | 275,500 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/07/2020 | 918,500 |
| MORRISSEY MICHAEL | President and CEO | 01/29/2020 | 137,750 |
| MORRISSEY MICHAEL | President and CEO | 01/29/2020 | 446,750 |
| MORRISSEY MICHAEL | President and CEO | 01/23/2020 | 137,750 |
| MORRISSEY MICHAEL | President and CEO | 01/23/2020 | 485,250 |
| SCANGOS GEORGE A | Director | 01/22/2020 | 493,750 |
| MARCHESI VINCENT T | Director | 01/15/2020 | 1,234,277 |
| MORRISSEY MICHAEL | President and CEO | 01/16/2020 | 137,750 |
| MORRISSEY MICHAEL | President and CEO | 01/16/2020 | 508,250 |
| SCANGOS GEORGE A | Director | 01/15/2020 | 509,750 |
| MORRISSEY MICHAEL | President and CEO | 01/08/2020 | 137,750 |
| MORRISSEY MICHAEL | President and CEO | 01/08/2020 | 471,250 |
| Garber Alan M | Director | 01/07/2020 | 468,884 |
| Garber Alan M | Director | 01/07/2020 | 1,566,078 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 01/07/2020 | 275,500 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 01/07/2020 | 898,000 |
| MORRISSEY MICHAEL | President and CEO | 01/02/2020 | 137,750 |
| MORRISSEY MICHAEL | President and CEO | 01/02/2020 | 437,250 |
| SCANGOS GEORGE A | Director | 12/27/2019 | 456,250 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 12/04/2019 | 71,157 |
| Hessekiel Jeffrey | EVP and General Counsel | 12/04/2019 | 41,701 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 12/04/2019 | 68,418 |
| Haley Patrick J. | Sr. Vice President, Commercial | 12/04/2019 | 35,464 |
| Senner Christopher J. | EVP and CFO | 12/04/2019 | 72,270 |
| MORRISSEY MICHAEL | President and CEO | 12/04/2019 | 172,954 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 12/03/2019 | 275,500 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 12/03/2019 | 811,000 |
| Hessekiel Jeffrey | EVP and General Counsel | 11/15/2019 | 143,439 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 11/15/2019 | 202,545 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 11/15/2019 | 151,909 |
| MORRISSEY MICHAEL | President and CEO | 11/15/2019 | 304,246 |
| Senner Christopher J. | EVP and CFO | 11/15/2019 | 178,622 |
| Haley Patrick J. | Sr. Vice President, Commercial | 11/15/2019 | 150,357 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 11/04/2019 | 275,500 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 11/04/2019 | 799,500 |
| Haley Patrick J. | Sr. Vice President, Commercial | 10/10/2019 | 4,930 |
| MORRISSEY MICHAEL | President and CEO | 10/02/2019 | 254,237 |
| MORRISSEY MICHAEL | President and CEO | 10/02/2019 | 465,588 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 10/01/2019 | 165,300 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 10/01/2019 | 536,100 |
| MORRISSEY MICHAEL | President and CEO | 09/18/2019 | 359,000 |
| MORRISSEY MICHAEL | President and CEO | 09/18/2019 | 714,758 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/12/2019 | 28,640 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 09/12/2019 | 49,710 |
| MORRISSEY MICHAEL | President and CEO | 09/12/2019 | 125,691 |
| Haley Patrick J. | Sr. Vice President, Commercial | 09/12/2019 | 25,770 |
| Senner Christopher J. | EVP and CFO | 09/12/2019 | 52,715 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 09/12/2019 | 49,633 |
| Haley Patrick J. | Sr. Vice President, Commercial | 09/10/2019 | 18,840 |
| Hessekiel Jeffrey | EVP and General Counsel | 08/16/2019 | 127,500 |
| Hessekiel Jeffrey | EVP and General Counsel | 08/16/2019 | 1,582,500 |
| POSTE GEORGE | Director | 08/16/2019 | 114,500 |
| POSTE GEORGE | Director | 08/16/2019 | 512,500 |
| MORRISSEY MICHAEL | President and CEO | 08/14/2019 | 359,000 |
| MORRISSEY MICHAEL | President and CEO | 08/14/2019 | 704,654 |
| Haley Patrick J. | Sr. Vice President, Commercial | 08/12/2019 | 20,390 |
| POSTE GEORGE | Director | 08/09/2019 | 111,700 |
| POSTE GEORGE | Director | 08/09/2019 | 412,000 |
| Haley Patrick J. | Sr. Vice President, Commercial | 08/06/2019 | 42,500 |
| Haley Patrick J. | Sr. Vice President, Commercial | 08/06/2019 | 500,500 |
| MORRISSEY MICHAEL | President and CEO | 08/02/2019 | 359,000 |
| MORRISSEY MICHAEL | President and CEO | 08/02/2019 | 709,560 |
| SCANGOS GEORGE A | Director | 08/01/2019 | 823,737 |
| MORRISSEY MICHAEL | President and CEO | 07/17/2019 | 359,000 |
| MORRISSEY MICHAEL | President and CEO | 07/17/2019 | 741,988 |
| Haley Patrick J. | Sr. Vice President, Commercial | 07/10/2019 | 20,960 |
| SCANGOS GEORGE A | Director | 07/01/2019 | 863,200 |
| MORRISSEY MICHAEL | President and CEO | 07/03/2019 | 359,000 |
| MORRISSEY MICHAEL | President and CEO | 07/03/2019 | 730,183 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/19/2019 | 95,896 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/18/2019 | 263,711 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/17/2019 | 538,259 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/18/2019 | 2,067,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/17/2019 | 2,410,307 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/13/2019 | 153,434 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 06/13/2019 | 552,748 |
| Haley Patrick J. | Sr. Vice President, Commercial | 06/10/2019 | 20,230 |
| SCANGOS GEORGE A | Director | 06/04/2019 | 300,000 |
| SCANGOS GEORGE A | Director | 06/03/2019 | 490,250 |
| MORRISSEY MICHAEL | President and CEO | 05/29/2019 | 104,763 |
| SCANGOS GEORGE A | Director | 05/21/2019 | 68,550 |
| Haley Patrick J. | Sr. Vice President, Commercial | 05/10/2019 | 19,580 |
| MORRISSEY MICHAEL | President and CEO | 05/08/2019 | 233,520 |
| MORRISSEY MICHAEL | President and CEO | 05/08/2019 | 846,300 |
| WILLSEY LANCE | Director | 05/08/2019 | 1,018,000 |
| Senner Christopher J. | EVP and CFO | 05/03/2019 | 750,603 |
| SCANGOS GEORGE A | Director | 05/02/2019 | 300,000 |
| SCANGOS GEORGE A | Director | 05/01/2019 | 493,750 |
| MORRISSEY MICHAEL | President and CEO | 04/24/2019 | 222,400 |
| MORRISSEY MICHAEL | President and CEO | 04/24/2019 | 830,000 |
| Haley Patrick J. | Sr. Vice President, Commercial | 04/10/2019 | 24,040 |
| MORRISSEY MICHAEL | President and CEO | 04/10/2019 | 222,400 |
| MORRISSEY MICHAEL | President and CEO | 04/10/2019 | 962,400 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 04/03/2019 | 453,123 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 04/03/2019 | 1,577,725 |
| WYSZOMIERSKI JACK L | Director | 04/01/2019 | 115,350 |
| WYSZOMIERSKI JACK L | Director | 04/01/2019 | 187,493 |
| SCANGOS GEORGE A | Director | 04/03/2019 | 125,150 |
| SCANGOS GEORGE A | Director | 04/01/2019 | 960,800 |
| Hessekiel Jeffrey | EVP and General Counsel | 04/01/2019 | 34,000 |
| Hessekiel Jeffrey | EVP and General Counsel | 04/01/2019 | 480,600 |
| Garber Alan M | Director | 04/01/2019 | 157,350 |
| Garber Alan M | Director | 04/01/2019 | 719,550 |
| MORRISSEY MICHAEL | President and CEO | 03/27/2019 | 222,400 |
| MORRISSEY MICHAEL | President and CEO | 03/27/2019 | 935,600 |
| POSTE GEORGE | Director | 03/29/2019 | 68,550 |
| POSTE GEORGE | Director | 03/29/2019 | 92,215 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 03/25/2019 | 718,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 03/25/2019 | 2,314,000 |
| Haley Patrick J. | Sr. Vice President, Commercial | 03/26/2019 | 13,986 |
| Haley Patrick J. | Sr. Vice President, Commercial | 03/26/2019 | 63,369 |
| SCANGOS GEORGE A | Director | 03/14/2019 | 125,000 |
| Haley Patrick J. | Sr. Vice President, Commercial | 03/14/2019 | 3,520 |
| Haley Patrick J. | Sr. Vice President, Commercial | 03/14/2019 | 50,000 |
| MORRISSEY MICHAEL | President and CEO | 03/13/2019 | 222,400 |
| MORRISSEY MICHAEL | President and CEO | 03/13/2019 | 985,485 |
| Haley Patrick J. | Sr. Vice President, Commercial | 03/11/2019 | 22,182 |
| MORRISSEY MICHAEL | President and CEO | 02/27/2019 | 222,400 |
| MORRISSEY MICHAEL | President and CEO | 02/27/2019 | 907,600 |
| SCANGOS GEORGE A | Director | 03/01/2019 | 906,400 |
| COHEN CHARLES | Director | 02/25/2019 | 115,350 |
| COHEN CHARLES | Director | 02/25/2019 | 116,911 |
| Haley Patrick J. | Sr. Vice President, Commercial | 02/25/2019 | 95,137 |
| PAPADOPOULOS STELIOS | Director | 02/21/2019 | 115,350 |
| PAPADOPOULOS STELIOS | Director | 02/21/2019 | 557,813 |
| WILLSEY LANCE | Director | 02/20/2019 | 115,350 |
| WILLSEY LANCE | Director | 02/20/2019 | 554,138 |
| MARCHESI VINCENT T | Director | 02/22/2019 | 204,150 |
| MARCHESI VINCENT T | Director | 02/22/2019 | 886,875 |
| COHEN CHARLES | Director | 02/19/2019 | 1,034,906 |
| COHEN CHARLES | Director | 02/15/2019 | 2,219,000 |
| COHEN CHARLES | Director | 02/14/2019 | 2,241,000 |
| MORRISSEY MICHAEL | President and CEO | 02/14/2019 | 222,400 |
| MORRISSEY MICHAEL | President and CEO | 02/14/2019 | 895,654 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/14/2019 | 556,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/15/2019 | 127,880 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/14/2019 | 2,166,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 02/15/2019 | 510,600 |
| FELDBAUM CARL B | Director | 02/14/2019 | 251,275 |
| FELDBAUM CARL B | Director | 02/14/2019 | 1,112,515 |
| Haley Patrick J. | Sr. Vice President, Commercial | 02/11/2019 | 21,300 |
| SCANGOS GEORGE A | Director | 02/01/2019 | 941,200 |
| MORRISSEY MICHAEL | President and CEO | 01/30/2019 | 222,400 |
| MORRISSEY MICHAEL | President and CEO | 01/30/2019 | 924,800 |
| MORRISSEY MICHAEL | President and CEO | 01/16/2019 | 222,400 |
| MORRISSEY MICHAEL | President and CEO | 01/16/2019 | 931,456 |
| Haley Patrick J. | Sr. Vice President, Commercial | 01/10/2019 | 3,520 |
| Haley Patrick J. | Sr. Vice President, Commercial | 01/10/2019 | 71,540 |
| Haley Patrick J. | Sr. Vice President, Commercial | 01/07/2019 | 16,119 |
| Haley Patrick J. | Sr. Vice President, Commercial | 01/09/2019 | 9,079 |
| Haley Patrick J. | Sr. Vice President, Commercial | 01/08/2019 | 3,520 |
| Haley Patrick J. | Sr. Vice President, Commercial | 01/09/2019 | 36,660 |
| Haley Patrick J. | Sr. Vice President, Commercial | 01/08/2019 | 46,000 |
| Haley Patrick J. | Sr. Vice President, Commercial | 01/07/2019 | 119,620 |
| Garber Alan M | Director | 01/08/2019 | 46,800 |
| Garber Alan M | Director | 01/08/2019 | 258,750 |
| MORRISSEY MICHAEL | President and CEO | 01/03/2019 | 19,855 |
| MORRISSEY MICHAEL | President and CEO | 01/02/2019 | 33,616 |
| MORRISSEY MICHAEL | President and CEO | 01/04/2019 | 168,929 |
| MORRISSEY MICHAEL | President and CEO | 01/02/2019 | 120,920 |
| MORRISSEY MICHAEL | President and CEO | 01/04/2019 | 611,914 |
| MORRISSEY MICHAEL | President and CEO | 01/03/2019 | 71,420 |
| SCANGOS GEORGE A | Director | 01/03/2019 | 1,920 |
| SCANGOS GEORGE A | Director | 01/02/2019 | 783,715 |
| Haley Patrick J. | Sr. Vice President, Commercial | 01/03/2019 | 14,080 |
| Haley Patrick J. | Sr. Vice President, Commercial | 01/03/2019 | 159,600 |
| SCANGOS GEORGE A | Director | 11/29/2018 | 130,000 |
| SCANGOS GEORGE A | Director | 12/03/2018 | 846,400 |
| SCANGOS GEORGE A | Director | 11/30/2018 | 170,000 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 12/03/2018 | 68,035 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 12/03/2018 | 283,749 |
| Hessekiel Jeffrey | EVP and General Counsel | 11/30/2018 | 38,685 |
| Hessekiel Jeffrey | EVP and General Counsel | 11/29/2018 | 21,773 |
| Hessekiel Jeffrey | EVP and General Counsel | 11/28/2018 | 224,832 |
| Senner Christopher J. | EVP and CFO | 11/30/2018 | 173,183 |
| Senner Christopher J. | EVP and CFO | 11/15/2018 | 135,482 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 11/15/2018 | 205,474 |
| MORRISSEY MICHAEL | President and CEO | 11/15/2018 | 302,810 |
| MORRISSEY MICHAEL | President and CEO | 11/15/2018 | 110,500 |
| MORRISSEY MICHAEL | President and CEO | 11/15/2018 | 430,500 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 11/15/2018 | 160,523 |
| Hessekiel Jeffrey | EVP and General Counsel | 11/15/2018 | 101,419 |
| Haley Patrick J. | Sr. Vice President, Commercial | 11/15/2018 | 158,900 |
| Haley Patrick J. | Sr. Vice President, Commercial | 11/07/2018 | 346,400 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 11/01/2018 | 60,480 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 11/01/2018 | 169,920 |
| SCANGOS GEORGE A | Director | 11/01/2018 | 366,400 |
| MORRISSEY MICHAEL | President and CEO | 11/02/2018 | 188,995 |
| MORRISSEY MICHAEL | President and CEO | 11/02/2018 | 658,964 |
| SCANGOS GEORGE A | Director | 10/01/2018 | 446,500 |
| MORRISSEY MICHAEL | President and CEO | 10/01/2018 | 63,005 |
| MORRISSEY MICHAEL | President and CEO | 10/01/2018 | 222,768 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 10/01/2018 | 60,480 |
| Schwab Gisela | Pres, Prod Dev & Med Aff & CMO | 10/01/2018 | 213,240 |
| SCANGOS GEORGE A | Director | 09/24/2018 | 421,250 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 09/04/2018 | 123,750 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 09/04/2018 | 416,925 |
| MORRISSEY MICHAEL | President and CEO | 08/20/2018 | 495,000 |
| MORRISSEY MICHAEL | President and CEO | 08/20/2018 | 1,604,216 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 08/17/2018 | 275,500 |
| MARCHESI VINCENT T | Director | 08/15/2018 | 135,200 |
| MARCHESI VINCENT T | Director | 08/15/2018 | 780,000 |
| SCANGOS GEORGE A | Director | 08/10/2018 | 525,332 |
| MORRISSEY MICHAEL | President and CEO | 08/07/2018 | 170,000 |
| MORRISSEY MICHAEL | President and CEO | 08/09/2018 | 58,254 |
| MORRISSEY MICHAEL | President and CEO | 08/08/2018 | 170,000 |
| MORRISSEY MICHAEL | President and CEO | 08/07/2018 | 2,110,000 |
| MORRISSEY MICHAEL | President and CEO | 08/09/2018 | 716,523 |
| MORRISSEY MICHAEL | President and CEO | 08/08/2018 | 2,102,000 |
| Haley Patrick J. | Sr. Vice President, Commercial | 08/06/2018 | 49,392 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 08/01/2018 | 123,750 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 08/01/2018 | 462,600 |
| MORRISSEY MICHAEL | President and CEO | 07/16/2018 | 495,000 |
| MORRISSEY MICHAEL | President and CEO | 07/16/2018 | 1,901,700 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 07/02/2018 | 123,750 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 07/02/2018 | 477,000 |
| MORRISSEY MICHAEL | President and CEO | 06/25/2018 | 495,000 |
| MORRISSEY MICHAEL | President and CEO | 06/25/2018 | 1,765,800 |
| Hessekiel Jeffrey | EVP and General Counsel | 05/31/2018 | 1,346,150 |
| FELDBAUM CARL B | Director | 05/30/2018 | 62,795 |
| FELDBAUM CARL B | Director | 05/30/2018 | 705,797 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 06/01/2018 | 123,750 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 06/01/2018 | 468,000 |
| WILLSEY LANCE | Director | 05/22/2018 | 1,070,000 |
| MORRISSEY MICHAEL | President and CEO | 05/24/2018 | 495,000 |
| MORRISSEY MICHAEL | President and CEO | 05/24/2018 | 1,849,500 |
| Haley Patrick J. | Sr. Vice President, Commercial | 05/18/2018 | 79,157 |
| SCANGOS GEORGE A | Director | 05/15/2018 | 174,900 |
| MARCHESI VINCENT T | Director | 05/11/2018 | 174,900 |
| MARCHESI VINCENT T | Director | 05/11/2018 | 285,450 |
| COHEN CHARLES | Director | 05/09/2018 | 174,900 |
| COHEN CHARLES | Director | 05/09/2018 | 321,300 |
| PAPADOPOULOS STELIOS | Director | 05/07/2018 | 174,900 |
| PAPADOPOULOS STELIOS | Director | 05/07/2018 | 332,250 |
| Hessekiel Jeffrey | EVP and General Counsel | 05/04/2018 | 447,200 |
| Haley Patrick J. | Sr. Vice President, Commercial | 05/07/2018 | 28,500 |
| Haley Patrick J. | Sr. Vice President, Commercial | 05/04/2018 | 19,000 |
| Haley Patrick J. | Sr. Vice President, Commercial | 05/07/2018 | 330,000 |
| Haley Patrick J. | Sr. Vice President, Commercial | 05/04/2018 | 280,847 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 05/03/2018 | 123,750 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 05/03/2018 | 519,417 |
| Hessekiel Jeffrey | EVP and General Counsel | 04/27/2018 | 42,500 |
| Haley Patrick J. | Sr. Vice President, Commercial | 04/24/2018 | 34,000 |
| WYSZOMIERSKI JACK L | Director | 04/16/2018 | 294,450 |
| WYSZOMIERSKI JACK L | Director | 04/16/2018 | 302,920 |
| Garber Alan M | Director | 04/16/2018 | 174,900 |
| Garber Alan M | Director | 04/16/2018 | 303,750 |
| MORRISSEY MICHAEL | President and CEO | 04/11/2018 | 495,000 |
| MORRISSEY MICHAEL | President and CEO | 04/11/2018 | 1,870,200 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 04/06/2018 | 104,763 |
| FELDBAUM CARL B | Director | 03/05/2018 | 128,260 |
| FELDBAUM CARL B | Director | 03/05/2018 | 262,680 |
| COHEN CHARLES | Director | 03/05/2018 | 119,550 |
| COHEN CHARLES | Director | 03/05/2018 | 363,450 |
| MARCHESI VINCENT T | Director | 03/06/2018 | 119,550 |
| MARCHESI VINCENT T | Director | 03/06/2018 | 370,950 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 03/01/2018 | 32,235 |
| PAPADOPOULOS STELIOS | Director | 03/02/2018 | 119,550 |
| PAPADOPOULOS STELIOS | Director | 03/02/2018 | 360,750 |
| WILLSEY LANCE | Director | 03/02/2018 | 294,450 |
| WILLSEY LANCE | Director | 03/02/2018 | 717,300 |
| Haley Patrick J. | Sr. Vice President, Commercial | 02/28/2018 | 35,200 |
| Haley Patrick J. | Sr. Vice President, Commercial | 02/28/2018 | 1,221,637 |
| POSTE GEORGE | Director | 02/28/2018 | 174,900 |
| POSTE GEORGE | Director | 02/28/2018 | 393,900 |
| Garber Alan M | Director | 01/09/2018 | 91,655 |
| Garber Alan M | Director | 01/08/2018 | 27,895 |
| Garber Alan M | Director | 01/09/2018 | 345,000 |
| Garber Alan M | Director | 01/08/2018 | 109,515 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 11/15/2017 | 54,549 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 11/15/2017 | 64,573 |
| Haley Patrick J. | Sr. Vice President, Commercial | 11/15/2017 | 92,540 |
| Hessekiel Jeffrey | EVP and General Counsel | 11/15/2017 | 52,470 |
| Senner Christopher J. | EVP and CFO | 11/15/2017 | 68,360 |
| MORRISSEY MICHAEL | President and CEO | 11/15/2017 | 206,588 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/27/2017 | 4,374 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/28/2017 | 47,500 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/28/2017 | 608,000 |
| Hessekiel Jeffrey | EVP and General Counsel | 09/27/2017 | 55,018 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 09/26/2017 | 330,330 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 09/28/2017 | 330,340 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 09/27/2017 | 330,330 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 09/28/2017 | 791,349 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 09/27/2017 | 797,992 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 09/26/2017 | 789,325 |
| PAPADOPOULOS STELIOS | Director | 09/22/2017 | 254,000 |
| PAPADOPOULOS STELIOS | Director | 09/19/2017 | 3,530,838 |
| PAPADOPOULOS STELIOS | Director | 09/18/2017 | 2,004,550 |
| Haley Patrick J. | Sr. Vice President, Commercial | 09/14/2017 | 1,650,014 |
| WILLSEY LANCE | Director | 09/13/2017 | 1,348,500 |
| WILLSEY LANCE | Director | 09/12/2017 | 1,339,500 |
| Senner Christopher J. | EVP and CFO | 09/12/2017 | 366,000 |
| Senner Christopher J. | EVP and CFO | 09/12/2017 | 2,679,000 |
| MORRISSEY MICHAEL | President and CEO | 09/12/2017 | 170,000 |
| MORRISSEY MICHAEL | President and CEO | 09/14/2017 | 170,000 |
| MORRISSEY MICHAEL | President and CEO | 09/13/2017 | 170,000 |
| MORRISSEY MICHAEL | President and CEO | 09/14/2017 | 2,708,000 |
| MORRISSEY MICHAEL | President and CEO | 09/13/2017 | 2,704,000 |
| MORRISSEY MICHAEL | President and CEO | 09/12/2017 | 2,659,000 |
| Haley Patrick J. | Sr. Vice President, Commercial | 05/30/2017 | 92,300 |
| FELDBAUM CARL B | Director | 05/15/2017 | 166,190 |
| FELDBAUM CARL B | Director | 05/15/2017 | 711,831 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 05/15/2017 | 63,005 |
| MORRISSEY MICHAEL | President and CEO | 05/10/2017 | 185,910 |
| MORRISSEY MICHAEL | President and CEO | 05/09/2017 | 190,000 |
| MORRISSEY MICHAEL | President and CEO | 05/08/2017 | 21,470 |
| MORRISSEY MICHAEL | President and CEO | 05/09/2017 | 2,168,706 |
| MORRISSEY MICHAEL | President and CEO | 05/08/2017 | 246,453 |
| MORRISSEY MICHAEL | President and CEO | 05/10/2017 | 2,207,000 |
| MORRISSEY MICHAEL | President and CEO | 05/04/2017 | 112,383 |
| MORRISSEY MICHAEL | President and CEO | 05/03/2017 | 190,000 |
| MORRISSEY MICHAEL | President and CEO | 05/05/2017 | 190,000 |
| MORRISSEY MICHAEL | President and CEO | 05/04/2017 | 1,311,333 |
| MORRISSEY MICHAEL | President and CEO | 05/03/2017 | 2,266,803 |
| MORRISSEY MICHAEL | President and CEO | 05/05/2017 | 2,184,702 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 05/01/2017 | 891,008 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 05/01/2017 | 2,068,519 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 04/17/2017 | 99,992 |
| MARCHESI VINCENT T | Director | 04/03/2017 | 105,300 |
| MARCHESI VINCENT T | Director | 04/03/2017 | 213,000 |
| WYSZOMIERSKI JACK L | Director | 03/31/2017 | 105,300 |
| WYSZOMIERSKI JACK L | Director | 03/31/2017 | 111,085 |
| COHEN CHARLES | Director | 03/27/2017 | 105,300 |
| Hessekiel Jeffrey | EVP and General Counsel | 03/27/2017 | 144,702 |
| Hessekiel Jeffrey | EVP and General Counsel | 03/22/2017 | 93,500 |
| Hessekiel Jeffrey | EVP and General Counsel | 03/22/2017 | 488,585 |
| FELDBAUM CARL B | Director | 03/20/2017 | 105,300 |
| FELDBAUM CARL B | Director | 03/20/2017 | 217,700 |
| PAPADOPOULOS STELIOS | Director | 03/20/2017 | 105,300 |
| PAPADOPOULOS STELIOS | Director | 03/20/2017 | 216,600 |
| WILLSEY LANCE | Director | 03/15/2017 | 105,300 |
| WILLSEY LANCE | Director | 03/15/2017 | 228,600 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 03/15/2017 | 310,179 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 03/15/2017 | 1,126,658 |
| COHEN CHARLES | Director | 03/13/2017 | 218,200 |
| MARCHESI VINCENT T | Director | 03/10/2017 | 125,200 |
| MARCHESI VINCENT T | Director | 03/10/2017 | 879,200 |
| Hessekiel Jeffrey | EVP and General Counsel | 03/03/2017 | 727,000 |
| Hessekiel Jeffrey | EVP and General Counsel | 03/03/2017 | 2,303,678 |
| MORRISSEY MICHAEL | President and CEO | 03/06/2017 | 991,000 |
| MORRISSEY MICHAEL | President and CEO | 03/03/2017 | 991,000 |
| MORRISSEY MICHAEL | President and CEO | 03/06/2017 | 2,261,000 |
| MORRISSEY MICHAEL | President and CEO | 03/03/2017 | 2,283,000 |
| Haley Patrick J. | Sr. Vice President, Commercial | 03/03/2017 | 57,600 |
| Senner Christopher J. | EVP and CFO | 03/03/2017 | 250,800 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 03/01/2017 | 331,350 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 03/01/2017 | 998,550 |
| POSTE GEORGE | Director | 03/01/2017 | 93,190 |
| POSTE GEORGE | Director | 03/02/2017 | 303,659 |
| POSTE GEORGE | Director | 03/01/2017 | 196,293 |
| POSTE GEORGE | Director | 03/02/2017 | 1,521,892 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 02/01/2017 | 484,300 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 02/01/2017 | 1,305,500 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 01/03/2017 | 401,800 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 01/03/2017 | 1,025,636 |
| FELDBAUM CARL B | Director | 12/16/2016 | 260,250 |
| FELDBAUM CARL B | Director | 12/16/2016 | 425,750 |
| Garber Alan M | Director | 12/09/2016 | 105,300 |
| Garber Alan M | Director | 12/09/2016 | 132,361 |
| SCANGOS GEORGE A | Director | 12/07/2016 | 3,200 |
| SCANGOS GEORGE A | Director | 12/05/2016 | 3,218,204 |
| SCANGOS GEORGE A | Director | 12/07/2016 | 3,150 |
| SCANGOS GEORGE A | Director | 12/05/2016 | 3,646,027 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 12/01/2016 | 368,800 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 12/01/2016 | 1,166,200 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 12/01/2016 | 197,780 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 12/01/2016 | 368,060 |
| Senner Christopher J. | EVP and CFO | 07/15/2016 | 394,578 |
| MORRISSEY MICHAEL | President and CEO | 11/09/2016 | 1,798,000 |
| MORRISSEY MICHAEL | President and CEO | 11/09/2016 | 3,000,000 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 11/09/2016 | 197,780 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 11/09/2016 | 330,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 11/09/2016 | 362,000 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 11/09/2016 | 920,500 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 08/31/2016 | 1,290,801 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 08/31/2016 | 1,440,082 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 08/04/2016 | 411,949 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 08/04/2016 | 465,718 |
| Hessekiel Jeffrey | EVP and General Counsel | 06/01/2016 | 340,000 |
| WILLSEY LANCE | Director | 05/11/2016 | 99,000 |
| WILLSEY LANCE | Director | 05/09/2016 | 198,900 |
| Schwab Gisela | Pres Prod Dev & Med Aff & CMO | 02/11/2016 | 105,974 |
| Lamb Peter | EVP, Scientific Strategy & CSO | 02/11/2016 | 106,907 |
| Hessekiel Jeffrey | EVP and General Counsel | 02/11/2016 | 82,047 |
| Senner Christopher J. | EVP and CFO | 02/11/2016 | 87,549 |
| MORRISSEY MICHAEL | President and CEO | 02/11/2016 | 181,226 |
| WILLSEY LANCE | Director | 12/11/2015 | 239,000 |
| WILLSEY LANCE | Director | 12/10/2015 | 249,550 |
| Lamb Peter | EVP, Discovery Research & CSO | 10/16/2015 | 290,221 |
| Lamb Peter | EVP, Discovery Research & CSO | 10/16/2015 | 298,984 |
| Lamb Peter | EVP, Discovery Research & CSO | 10/13/2015 | 3,378 |
| Lamb Peter | EVP, Discovery Research & CSO | 10/12/2015 | 1,690,554 |
| Lamb Peter | EVP, Discovery Research & CSO | 10/13/2015 | 3,480 |
| Lamb Peter | EVP, Discovery Research & CSO | 10/12/2015 | 1,753,312 |
| MARCHESI VINCENT T | Director | 09/17/2014 | 34,199 |
| WILLSEY LANCE | Director | 08/29/2013 | 51,454 |
| MARCHESI VINCENT T | Director | 12/20/2012 | 18,720 |
| MARCHESI VINCENT T | Director | 12/19/2012 | 7,005 |
| MARCHESI VINCENT T | Director | 12/18/2012 | 7,230 |
| MARCHESI VINCENT T | Director | 12/17/2012 | 14,093 |
| Schwab Gisela | EVP and Chief Medical Officer | 12/10/2012 | 109,750 |
| MARCHESI VINCENT T | Director | 06/14/2012 | 35,911 |
| RIVERA LUPE M | EVP, Operations | 12/17/2010 | 160,317 |
| RIVERA LUPE M | EVP, Operations | 12/17/2010 | 250,130 |
| RIVERA LUPE M | EVP, Operations | 12/15/2010 | 281,500 |
| RIVERA LUPE M | EVP, Operations | 12/14/2010 | 140,750 |
| RIVERA LUPE M | EVP, Operations | 12/15/2010 | 387,500 |
| RIVERA LUPE M | EVP, Operations | 12/14/2010 | 175,000 |
| Schwab Gisela | EVP & Chief Medical Officer | 12/09/2010 | 26,728 |
| WILLSEY LANCE | Director | 09/07/2010 | 77,171 |
| WILLSEY LANCE | Director | 09/03/2010 | 53,299 |
| WILLSEY LANCE | Director | 08/30/2010 | 226,515 |
| WILLSEY LANCE | Director | 08/27/2010 | 93,539 |
| KARBE FRANK | EVP & CFO | 08/24/2010 | 49,165 |
| PAPADOPOULOS STELIOS | Director | 08/24/2010 | 610,197 |
| WILLSEY LANCE | Director | 08/16/2010 | 155,350 |
| WILLSEY LANCE | Director | 08/13/2010 | 137,690 |
| MORRISSEY MICHAEL | President & CEO | 08/13/2010 | 88,344 |
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FUNDS WITH A POSITION IN EXELIXIS INC
| Fund | # Shares Owned | % of Portfolio | % Change | Investing Style |
|---|---|---|---|---|
| BLACKROCK INC. | 36,014,432 | 0.02% | -2.73% | Other |
| FARALLON CAPITAL MANAGEMENT LLC | 26,634,500 | 3.17% | 2.99% | Event Driven, Value |
| RENAISSANCE TECHNOLOGIES LLC | 15,615,716 | 0.58% | 2.62% | Other |
| GEODE CAPITAL MANAGEMENT, LLC | 5,145,318 | 0.01% | 1.39% | Other |
| FULLER & THALER ASSET MANAGEMENT, INC. | 2,615,300 | 0.32% | 2.1% | Other |
| AQR CAPITAL MANAGEMENT LLC | 2,178,705 | 0.1% | 8.08% | Other |
| D. E. SHAW & CO., INC. | 854,140 | 0.02% | -43.04% | Other |
| CANDRIAM S.C.A. | 711,625 | 0.12% | No change | Other |
| GOTHAM ASSET MANAGEMENT, LLC | 156,395 | 0.07% | 5.45% | Other |
| TUDOR INVESTMENT CORP ET AL | 139,210 | 0.03% | -18.15% | Event Driven, Other |
| FIRST EAGLE INVESTMENT MANAGEMENT, LLC | 25,195 | 0.00144% | No change | Value |
| PZENA INVESTMENT MANAGEMENT LLC | 18,979 | 0.00171% | -13.84% | Value |
| BALYASNY ASSET MANAGEMENT L.P. | 15,726 | 0.00071% | 44.95% | Event Driven |
| DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 8,400 | 0.00372% | New | Other |
CHANGE IN SHARES OUTSTANDING FOR EXELIXIS INC
STOCK BUYBACKS FOR EXELIXIS INC
Period of Report
Previous Period
% Change in Shares
10-K/10-Q Filings
Quarter
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Period of Report: 12/31/2023
10-K/10-Q Filings: View
Previous Period
% Change in Shares
Quarter
09/30/2023
-1.95%
1Q
06/30/2023
-4.36%
2Q
03/31/2023
-4.06%
3Q
12/31/2022
-3.67%
4Q
09/30/2022
-3.70%
5Q
06/30/2022
-3.66%
6Q
03/31/2022
-3.17%
7Q
12/31/2021
-3.14%
8Q
09/30/2021
-2.79%
9Q
06/30/2021
-3.07%
10Q
03/31/2021
-2.57%
11Q
12/31/2020
-2.03%
12Q
09/30/2020
1.26%
13Q
06/30/2020
-1.61%
14Q
03/31/2020
-0.89%
15Q
12/31/2019
-0.59%
16Q
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BUYBACK ANNOUNCEMENT(S) FOR EXELIXIS INC
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