Seagen Inc. (SGEN) NASDAQ

$139.43 0.40 (0.29%)

Market Cap: $25.81B

As of 02/02/23 04:00 PM EST. Market closed.

(SGEN)

Seagen Inc. (SGEN) NASDAQ

$139.43 0.40 (0.29%)

Market Cap: $25.81B

As of 02/02/23 04:00 PM EST. Market closed.

Seagen Inc. is a global biotechnology company that discovers, develops and commercializes transformative cancer medicines to make a meaningful difference in people’s lives. Seagen is headquartered in the Seattle, Washington area, and has locations in California, Canada, Switzerland and the European ... read more

Seagen Inc. is a global biotechnology company that discovers, develops and commercializes transformative cancer medicines to make a meaningful difference in people’s lives. Seagen is headquartered in the Seattle, Washington area, and has locations in California, Canada, Switzerland and the European Union. read less

COMPANY PROFILE
Sector
Manufacturing
Industry
Biological Product (except Diagnostic) Manufacturing
CEO Compensation (Base)
$918,554
CEO Compensation (Total)
$18.11M
URL
Address
.
Sector
Manufacturing
Industry
Biological Product (except Diagnostic) Manufacturing
Full Time Employees
2,675
CEO Compensation (Base)
$918,554
CEO Compensation (Total)
$18.11M
Address
.
PRICE CHART
1w
1m
3m
6m
YTD
1y
5y
MAX
From: To:
NEWS
KEY STATS
Open
$139.19
Previous Close
$139.03
Days Range
$135.85 - $140
52 week range
$105.43 - $183
Volume
888,770
Avg. Volume (30 days)
1,005,733
Market Cap
$25.81B
Dividend Yield
0.00%
P/E
-40.54
Shares Outstanding
185,664,901
Open
$139.19
Previous Close
$139.03
Days Range
$135.85 - $140
52 week range
$105.43 - $183
Volume
888,770
Avg. Volume (30 days)
1,005,733
Market Cap
$25.81B
Dividend Yield
0.00%
P/E
-40.54
Shares Outstanding
185,664,901

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

INSIDER TRANSACTIONS FOR SEAGEN INC
Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
DANSEY ROGER D President, R&D & CMO Jan 24, 2023 Option Exercise $72.64 10,000 726,400 107,539 Jan 26, 2023, 07:41 PM
DANSEY ROGER D President, R&D & CMO Jan 24, 2023 Sale $135.00 10,000 1,350,000 97,539 Jan 26, 2023, 07:41 PM
LIU JEAN I Chief Legal Officer Jan 24, 2023 Option Exercise $39.15 5,000 195,750 90,113 Jan 26, 2023, 07:39 PM
LIU JEAN I Chief Legal Officer Jan 24, 2023 Sale $135.03 5,000 675,134 85,113 Jan 26, 2023, 07:39 PM
LIU JEAN I Chief Legal Officer Jan 17, 2023 Sale $130.71 578 75,548 85,113 Jan 19, 2023, 07:16 PM
DANSEY ROGER D President R&D & CMO Jan 05, 2023 Option Exercise $72.64 7,500 544,800 105,039 Jan 06, 2023, 07:10 PM
DANSEY ROGER D President R&D & CMO Jan 04, 2023 Option Exercise $72.64 2,500 181,600 100,039 Jan 06, 2023, 07:10 PM
DANSEY ROGER D President R&D & CMO Jan 05, 2023 Sale $135.00 7,500 1,012,500 97,539 Jan 06, 2023, 07:10 PM
DANSEY ROGER D President R&D & CMO Jan 04, 2023 Sale $135.00 2,500 337,500 97,539 Jan 06, 2023, 07:10 PM
LIU JEAN I Chief Legal Officer Jan 04, 2023 Option Exercise $39.15 475 18,596 86,166 Jan 06, 2023, 07:08 PM
LIU JEAN I Chief Legal Officer Jan 05, 2023 Option Exercise $39.15 4,525 177,154 90,216 Jan 06, 2023, 07:08 PM
LIU JEAN I Chief Legal Officer Jan 05, 2023 Sale $135.00 4,525 610,875 85,691 Jan 06, 2023, 07:08 PM
LIU JEAN I Chief Legal Officer Jan 04, 2023 Sale $135.00 475 64,125 85,691 Jan 06, 2023, 07:08 PM
ROMP CHARLES R EVP, Commercial U.S. Dec 20, 2022 Sale $127.63 1,129 144,094 58,475 Dec 21, 2022, 06:48 PM
DANSEY ROGER D President, Research and Develo Dec 14, 2022 Option Exercise $77.16 10,000 771,628 106,942 Dec 16, 2022, 07:42 PM
DANSEY ROGER D President, Research and Develo Dec 14, 2022 Sale $135.00 10,000 1,350,000 97,539 Dec 16, 2022, 07:42 PM
Simonian Nancy A Director Dec 12, 2022 Option Exercise $36.70 8,750 321,125 62,753 Dec 14, 2022, 05:49 PM
LIU JEAN I Chief Legal Officer Nov 17, 2022 Option Exercise $34.20 8,333 284,989 94,024 Nov 18, 2022, 07:53 PM
LIU JEAN I Chief Legal Officer Nov 17, 2022 Sale $131.05 8,333 1,092,056 85,691 Nov 18, 2022, 07:53 PM
LIU JEAN I Chief Legal Officer Nov 14, 2022 Option Exercise $76.86 1,301 99,995 85,691 Nov 16, 2022, 06:22 PM
GRYSKA DAVID W Director Nov 11, 2022 Sale $129.10 7,500 968,220 40,253 Nov 15, 2022, 05:46 PM
DANSEY ROGER D Interim CEO & CMO Oct 17, 2022 Option Exercise $74.54 10,000 745,421 102,146 Oct 19, 2022, 07:17 PM
DANSEY ROGER D Interim CEO & CMO Oct 17, 2022 Sale $135.00 10,000 1,350,000 97,539 Oct 19, 2022, 07:17 PM
SIMPSON TODD E Chief Financial Officer Aug 31, 2022 Sale $154.41 4,186 646,381 139,249 Sep 01, 2022, 06:09 PM
HIMES VAUGHN B Chief Technical Officer Aug 31, 2022 Sale $154.41 3,584 553,423 68,972 Sep 01, 2022, 06:07 PM
ROMP CHARLES R EVP, Commercial Aug 31, 2022 Sale $154.41 1,133 174,952 60,159 Sep 01, 2022, 06:06 PM
DANSEY ROGER D Interim CEO & CMO Aug 31, 2022 Sale $154.41 5,019 775,009 101,752 Sep 01, 2022, 06:03 PM
LIU JEAN I Chief Legal Officer Aug 31, 2022 Sale $154.41 3,648 563,306 86,283 Sep 01, 2022, 06:03 PM
SIMPSON TODD E Chief Financial Officer Aug 16, 2022 Sale $170.21 1,967 334,813 142,477 Aug 17, 2022, 09:19 PM
ROMP CHARLES R EVP, Commercial Aug 16, 2022 Sale $170.21 1,765 300,429 61,725 Aug 17, 2022, 09:16 PM
LIU JEAN I Chief Legal Officer Aug 16, 2022 Sale $170.21 1,639 278,982 88,755 Aug 17, 2022, 09:14 PM
HIMES VAUGHN B Chief Technical Officer Aug 16, 2022 Sale $170.21 1,527 259,918 71,636 Aug 17, 2022, 09:13 PM
DANSEY ROGER D Interim CEO & CMO Aug 16, 2022 Sale $170.21 4,254 724,095 104,406 Aug 17, 2022, 09:12 PM
ROMP CHARLES R EVP, Commercial Jul 05, 2022 Sale $179.46 712 127,776 48,771 Jul 07, 2022, 06:50 PM
DANSEY ROGER D Chief Medical Officer Jun 28, 2022 Option Exercise $65.11 19,744 1,285,532 94,336 Jun 30, 2022, 06:02 PM
DANSEY ROGER D Chief Medical Officer Jun 28, 2022 Sale $180.00 34,635 6,234,300 76,975 Jun 30, 2022, 06:02 PM
HIMES VAUGHN B Chief Technical Officer Jun 17, 2022 Option Exercise $41.04 1,134 46,539 60,198 Jun 22, 2022, 07:03 PM
HIMES VAUGHN B Chief Technical Officer Jun 17, 2022 Sale $160.00 1,134 181,440 119,471 Jun 22, 2022, 07:03 PM
HIMES VAUGHN B Chief Technical Officer May 24, 2022 Option Exercise $26.10 10,866 283,603 67,359 May 26, 2022, 06:07 PM
HIMES VAUGHN B Chief Technical Officer May 24, 2022 Sale $136.79 10,866 1,486,376 59,064 May 26, 2022, 06:07 PM
ROMP CHARLES R EVP, Commercial May 16, 2022 Sale $134.21 333 44,691 49,483 May 18, 2022, 07:34 PM
SIEGALL CLAY B President & CEO May 12, 2022 Option Exercise $26.10 17,043 444,822 676,653 May 13, 2022, 07:13 PM
SIEGALL CLAY B President & CEO May 12, 2022 Sale $125.69 17,043 2,142,117 666,060 May 13, 2022, 07:13 PM
SIEGALL CLAY B President & CEO Apr 20, 2022 Sale $144.32 1,885 272,041 666,060 Apr 22, 2022, 08:34 PM
SIMPSON TODD E Chief Financial Officer Apr 20, 2022 Sale $144.32 567 81,829 127,891 Apr 22, 2022, 08:32 PM
LIU JEAN I Chief Legal Officer Apr 20, 2022 Sale $144.32 401 57,872 75,946 Apr 22, 2022, 08:31 PM
ROMP CHARLES R EVP, Commercial Apr 20, 2022 Sale $144.32 319 46,038 49,816 Apr 22, 2022, 08:30 PM
HIMES VAUGHN B Chief Technical Officer Apr 20, 2022 Sale $144.32 574 82,839 59,064 Apr 22, 2022, 08:29 PM
DANSEY ROGER D Chief Medical Officer Apr 21, 2022 Sale $144.15 652 93,986 76,975 Apr 22, 2022, 08:27 PM
DANSEY ROGER D Chief Medical Officer Apr 20, 2022 Sale $144.32 787 113,579 77,627 Apr 22, 2022, 08:27 PM
GRYSKA DAVID W Director Apr 19, 2022 Option Exercise $20.06 4,000 80,240 48,044 Apr 21, 2022, 06:37 PM
GRYSKA DAVID W Director Apr 19, 2022 Sale $143.95 4,000 575,783 46,250 Apr 21, 2022, 06:37 PM
SIEGALL CLAY B President and CEO Apr 07, 2022 Option Exercise $26.10 17,043 444,822 672,637 Apr 08, 2022, 09:41 PM
SIEGALL CLAY B President and CEO Apr 07, 2022 Sale $154.23 17,043 2,628,610 667,945 Apr 08, 2022, 09:41 PM
BAKER BROS. ADVISORS LP Director Mar 08, 2022 Option Exercise $20.06 35,000 702,100 42,965,004 Mar 10, 2022, 04:39 PM
SIEGALL CLAY B President & CEO Mar 07, 2022 Option Exercise $26.10 17,043 444,822 674,588 Mar 09, 2022, 07:42 PM
SIEGALL CLAY B President & CEO Mar 07, 2022 Sale $134.35 17,043 2,289,655 667,945 Mar 09, 2022, 07:42 PM
HIMES VAUGHN B Chief Technical Officer Mar 03, 2022 Option Exercise $26.10 12,000 313,200 70,343 Mar 04, 2022, 07:24 PM
HIMES VAUGHN B Chief Technical Officer Mar 03, 2022 Sale $127.05 12,000 1,524,558 59,500 Mar 04, 2022, 07:24 PM
Simonian Nancy A Director Mar 02, 2022 Option Exercise $20.04 25,000 501,000 52,500 Mar 04, 2022, 05:09 PM
SIEGALL CLAY B President & CEO Feb 07, 2022 Option Exercise $26.10 17,043 444,822 676,930 Feb 09, 2022, 07:02 PM
SIEGALL CLAY B President & CEO Feb 07, 2022 Sale $139.97 17,043 2,385,566 667,945 Feb 09, 2022, 07:02 PM
GRYSKA DAVID W Director Feb 07, 2022 Option Exercise $20.06 4,500 90,270 48,621 Feb 09, 2022, 06:58 PM
GRYSKA DAVID W Director Feb 07, 2022 Sale $138.76 4,500 624,441 46,250 Feb 09, 2022, 06:58 PM
DANSEY ROGER D Chief Medical Officer Feb 03, 2022 Sale $136.14 703 95,706 78,244 Feb 04, 2022, 05:54 PM
DANSEY ROGER D Chief Medical Officer Feb 02, 2022 Sale $137.58 739 101,672 78,947 Feb 04, 2022, 05:54 PM
GRYSKA DAVID W Director Jan 28, 2022 Option Exercise $20.06 4,500 90,270 48,803 Feb 01, 2022, 06:42 PM
GRYSKA DAVID W Director Jan 28, 2022 Sale $122.56 4,500 551,539 46,250 Feb 01, 2022, 06:42 PM
GRYSKA DAVID W Director Jan 14, 2022 Option Exercise $20.06 4,500 90,270 50,750 Jan 19, 2022, 06:26 PM
GRYSKA DAVID W Director Jan 14, 2022 Sale $135.24 4,500 608,580 46,250 Jan 19, 2022, 06:26 PM
SIEGALL CLAY B President & CEO Jan 07, 2022 Option Exercise $26.10 17,044 444,848 676,108 Jan 11, 2022, 07:14 PM
SIEGALL CLAY B President & CEO Jan 07, 2022 Sale $144.73 17,044 2,466,743 667,945 Jan 11, 2022, 07:14 PM
DANSEY ROGER D Chief Medical Officer Jan 03, 2022 Sale $152.58 8,675 1,323,649 84,891 Jan 05, 2022, 05:32 PM
ROMP CHARLES R EVP, Commercial Dec 20, 2021 Sale $149.85 1,323 198,252 51,102 Dec 22, 2021, 05:34 PM
HIMES VAUGHN B Chief Technical Officer Dec 20, 2021 Sale $149.85 345 51,698 59,500 Dec 22, 2021, 05:33 PM
DANSEY ROGER D Chief Medical Officer Dec 21, 2021 Sale $155.58 280 43,562 88,361 Dec 22, 2021, 05:33 PM
DANSEY ROGER D Chief Medical Officer Dec 20, 2021 Sale $149.85 280 41,958 88,641 Dec 22, 2021, 05:33 PM
SIEGALL CLAY B President & CEO Dec 20, 2021 Sale $149.85 1,227 183,866 667,945 Dec 22, 2021, 05:32 PM
SIMPSON TODD E Chief Financial Officer Dec 20, 2021 Sale $149.85 345 51,698 128,458 Dec 22, 2021, 05:31 PM
LIU JEAN I Chief Legal Officer Dec 20, 2021 Sale $149.85 276 41,359 70,432 Dec 22, 2021, 05:31 PM
SIEGALL CLAY B President & CEO Dec 07, 2021 Option Exercise $26.10 45,449 1,186,219 683,863 Dec 09, 2021, 06:49 PM
SIEGALL CLAY B President & CEO Dec 07, 2021 Sale $148.66 45,449 6,756,632 669,172 Dec 09, 2021, 06:49 PM
BAKER BROS. ADVISORS LP Director Nov 30, 2021 Sale $160.33 301,444 48,331,458 43,100,476 Dec 02, 2021, 06:51 PM
BAKER BROS. ADVISORS LP Director Dec 01, 2021 Sale $161.21 93,451 15,064,917 43,007,235 Dec 02, 2021, 06:51 PM
HIMES VAUGHN B Chief Technical Officer Nov 11, 2021 Option Exercise $26.10 6,000 156,600 65,845 Nov 12, 2021, 06:51 PM
HIMES VAUGHN B Chief Technical Officer Nov 11, 2021 Sale $178.63 6,000 1,071,774 63,828 Nov 12, 2021, 06:51 PM
LIU JEAN I GC/EVP, Leg Affairs Nov 04, 2021 Option Exercise $46.37 1,617 74,980 70,708 Nov 05, 2021, 05:21 PM
SIMPSON TODD E Chief Financial Officer Nov 04, 2021 Option Exercise $46.37 2,156 99,974 128,803 Nov 05, 2021, 05:21 PM
SIMPSON TODD E Chief Financial Officer Nov 03, 2021 Option Exercise $44.09 40,232 1,773,829 166,879 Nov 05, 2021, 05:21 PM
SIMPSON TODD E Chief Financial Officer Nov 03, 2021 Sale $185.00 40,232 7,442,920 126,647 Nov 05, 2021, 05:21 PM
LIU JEAN I GC/EVP, Leg Afairs Nov 01, 2021 Option Exercise $35.95 34,876 1,253,792 103,967 Nov 03, 2021, 09:18 PM
LIU JEAN I GC/EVP, Leg Afairs Nov 01, 2021 Sale $177.41 34,876 6,187,369 101,887 Nov 03, 2021, 09:18 PM
HIMES VAUGHN B Chief Technical Officer Nov 01, 2021 Option Exercise $46.37 2,156 99,974 59,845 Nov 03, 2021, 07:20 PM
SIMPSON TODD E Chief Financial Officer Oct 29, 2021 Option Exercise $41.04 33,564 1,377,467 160,211 Nov 02, 2021, 06:46 PM
SIMPSON TODD E Chief Financial Officer Oct 29, 2021 Sale $180.00 33,564 6,041,520 126,647 Nov 02, 2021, 06:46 PM
SIMPSON TODD E Chief Financial Officer Sep 23, 2021 Option Exercise $166.22 201 33,410 126,647 Sep 27, 2021, 08:10 PM
SIEGALL CLAY B President & CEO Sep 23, 2021 Option Exercise $166.22 714 118,681 669,172 Sep 27, 2021, 08:10 PM
ROMP CHARLES R EVP, Commercial Sep 23, 2021 Option Exercise $166.22 112 18,617 51,296 Sep 27, 2021, 08:10 PM
HIMES VAUGHN B Chief Technical Officer Sep 23, 2021 Option Exercise $166.22 201 33,410 57,689 Sep 27, 2021, 08:09 PM
LIU JEAN I GC/EVP, Legal Affairs Sep 23, 2021 Option Exercise $166.22 160 26,595 69,091 Sep 27, 2021, 08:09 PM
DANSEY ROGER D Chief Medical Officer Sep 23, 2021 Option Exercise $166.22 3,582 595,400 88,921 Sep 27, 2021, 08:08 PM
HIMES VAUGHN B Chief Technical Officer Sep 08, 2021 Option Exercise $26.10 6,000 156,600 63,488 Sep 10, 2021, 07:22 PM
HIMES VAUGHN B Chief Technical Officer Sep 08, 2021 Sale $150.00 6,000 900,000 57,488 Sep 10, 2021, 07:22 PM
DANSEY ROGER D Chief Medical Officer Aug 31, 2021 Sale $167.52 4,611 772,416 86,249 Sep 02, 2021, 08:07 PM
SIEGALL CLAY B President & CEO Aug 31, 2021 Sale $167.52 14,351 2,404,022 673,245 Sep 02, 2021, 07:59 PM
LIU JEAN I GC/EVP, Legal Affairs Aug 31, 2021 Sale $167.52 3,648 611,098 70,686 Sep 02, 2021, 07:58 PM
SIMPSON TODD E Chief Financial Officer Aug 31, 2021 Sale $167.52 3,987 667,886 128,568 Sep 02, 2021, 07:57 PM
HIMES VAUGHN B Chief Technical Officer Aug 31, 2021 Sale $167.52 3,584 600,377 59,283 Sep 02, 2021, 07:53 PM
ROMP CHARLES R EVP, Commercial Aug 31, 2021 Sale $167.52 1,133 189,796 51,739 Sep 02, 2021, 07:49 PM
SIEGALL CLAY B President and CEO Aug 31, 2021 Sale $169.92 10,432 1,772,575 691,471 Aug 31, 2021, 09:28 PM
SIEGALL CLAY B President and CEO Aug 30, 2021 Sale $166.86 35,706 5,957,815 696,147 Aug 31, 2021, 09:28 PM
SIEGALL CLAY B President and CEO Aug 27, 2021 Sale $169.05 14,294 2,416,390 731,028 Aug 31, 2021, 09:28 PM
ROMP CHARLES R EVP, Commercial Aug 16, 2021 Sale $154.55 777 120,088 42,410 Aug 18, 2021, 08:29 PM
SIEGALL CLAY B President & CEO Aug 16, 2021 Sale $154.55 2,789 431,051 712,420 Aug 18, 2021, 08:29 PM
HIMES VAUGHN B Chief Technical Officer Aug 16, 2021 Sale $154.55 658 101,697 52,354 Aug 18, 2021, 08:29 PM
DANSEY ROGER D Chief Medical Officer Aug 16, 2021 Sale $154.55 1,657 256,096 72,778 Aug 18, 2021, 08:28 PM
LIU JEAN I GC/EVP, Leg Affairs Aug 16, 2021 Sale $154.55 718 110,970 63,333 Aug 18, 2021, 08:28 PM
SIMPSON TODD E Chief Financial Officer Aug 16, 2021 Sale $154.55 533 82,377 119,338 Aug 18, 2021, 08:28 PM
DANSEY ROGER D Chief Medical Officer Aug 13, 2021 Sale $156.59 10,000 1,565,867 74,535 Aug 13, 2021, 09:39 PM
SIEGALL CLAY B President & CEO Aug 05, 2021 Option Exercise $15.46 23,560 364,238 724,471 Aug 06, 2021, 08:28 PM
SIEGALL CLAY B President & CEO Aug 06, 2021 Option Exercise $15.46 5,793 89,560 718,885 Aug 06, 2021, 08:28 PM
SIEGALL CLAY B President & CEO Aug 06, 2021 Sale $159.70 5,793 925,134 715,209 Aug 06, 2021, 08:28 PM
SIEGALL CLAY B President & CEO Aug 05, 2021 Sale $163.08 23,560 3,842,086 715,209 Aug 06, 2021, 08:28 PM
SIEGALL CLAY B President and CEO Jul 02, 2021 Option Exercise $15.46 15,268 236,043 722,621 Jul 06, 2021, 09:40 PM
SIEGALL CLAY B President and CEO Jul 01, 2021 Option Exercise $15.46 14,085 217,754 721,374 Jul 06, 2021, 09:40 PM
SIEGALL CLAY B President and CEO Jul 02, 2021 Sale $156.36 15,268 2,387,233 715,209 Jul 06, 2021, 09:40 PM
SIEGALL CLAY B President and CEO Jul 01, 2021 Sale $157.78 14,085 2,222,376 715,209 Jul 06, 2021, 09:40 PM
ROMP CHARLES R EVP, Commercial Jul 02, 2021 Sale $158.41 703 111,362 43,187 Jul 06, 2021, 08:13 PM
HIMES VAUGHN B Chief Technical Officer Jun 07, 2021 Option Exercise $26.10 1,303 34,008 54,315 Jun 08, 2021, 08:50 PM
HIMES VAUGHN B Chief Technical Officer Jun 07, 2021 Sale $150.00 1,303 195,450 53,012 Jun 08, 2021, 08:50 PM
SIEGALL CLAY B President and CEO Jun 03, 2021 Option Exercise $15.46 29,353 453,797 723,884 Jun 04, 2021, 08:22 PM
SIEGALL CLAY B President and CEO Jun 03, 2021 Sale $144.51 29,353 4,241,801 715,209 Jun 04, 2021, 08:22 PM
HIMES VAUGHN B Chief Technical Officer Jun 03, 2021 Option Exercise $15.46 10,697 165,376 63,709 Jun 04, 2021, 08:21 PM
HIMES VAUGHN B Chief Technical Officer Jun 03, 2021 Sale $144.91 10,697 1,550,090 61,709 Jun 04, 2021, 08:21 PM
LIU JEAN I GC/EVP, Leg Affairs May 11, 2021 Sale $140.00 1,061 148,540 64,051 May 13, 2021, 07:17 PM
SIEGALL CLAY B President and CEO Apr 09, 2021 Option Exercise $15.46 12,602 194,827 721,310 Apr 09, 2021, 08:13 PM
SIEGALL CLAY B President and CEO Apr 08, 2021 Option Exercise $15.46 16,751 258,970 724,376 Apr 09, 2021, 08:13 PM
SIEGALL CLAY B President and CEO Apr 09, 2021 Sale $141.96 12,602 1,788,924 715,209 Apr 09, 2021, 08:13 PM
SIEGALL CLAY B President and CEO Apr 08, 2021 Sale $145.17 16,751 2,431,816 715,209 Apr 09, 2021, 08:13 PM
SIEGALL CLAY B President and CEO Mar 04, 2021 Option Exercise $15.46 29,353 453,797 726,618 Mar 05, 2021, 07:56 PM
SIEGALL CLAY B President and CEO Mar 04, 2021 Sale $145.74 29,353 4,277,763 715,209 Mar 05, 2021, 07:56 PM
HIMES VAUGHN B Chief Technical Officer Mar 02, 2021 Option Exercise $15.46 12,000 185,520 141,889 Mar 04, 2021, 07:27 PM
HIMES VAUGHN B Chief Technical Officer Mar 02, 2021 Sale $153.22 12,000 1,838,623 138,889 Mar 04, 2021, 07:27 PM
LIU JEAN I GC/EVP, Leg Affairs Feb 17, 2021 Option Exercise $41.37 4,846 200,466 65,112 Feb 18, 2021, 08:48 PM
SIEGALL CLAY B President and CEO Feb 04, 2021 Option Exercise $15.46 29,353 453,797 726,706 Feb 05, 2021, 08:00 PM
SIEGALL CLAY B President and CEO Feb 04, 2021 Sale $165.57 29,353 4,860,105 715,209 Feb 05, 2021, 08:00 PM
DANSEY ROGER D Chief Medical Officer Feb 02, 2021 Option Exercise $163.97 728 119,370 109,544 Feb 04, 2021, 08:08 PM
LIU JEAN I GC/EVP, Leg Affairs Jan 15, 2021 Option Exercise $35.95 5,000 179,750 65,266 Jan 15, 2021, 07:40 PM
LIU JEAN I GC/EVP, Leg Affairs Jan 15, 2021 Sale $180.00 5,000 900,000 60,266 Jan 15, 2021, 07:40 PM
SIEGALL CLAY B President and CEO Jan 07, 2021 Option Exercise $15.46 29,353 453,797 719,687 Jan 08, 2021, 07:52 PM
SIEGALL CLAY B President and CEO Jan 07, 2021 Sale $172.44 29,353 5,061,681 715,209 Jan 08, 2021, 07:52 PM
SIMPSON TODD E Chief Financial Officer Dec 18, 2020 Option Exercise $26.71 34,773 928,772 152,436 Dec 18, 2020, 08:51 PM
SIMPSON TODD E Chief Financial Officer Dec 18, 2020 Sale $200.00 33,669 6,733,800 118,767 Dec 18, 2020, 08:51 PM
LIU JEAN I GC/EVP, Leg Affairs Dec 14, 2020 Option Exercise $35.95 5,000 179,750 63,642 Dec 16, 2020, 07:41 PM
LIU JEAN I GC/EVP, Leg Affairs Dec 16, 2020 Option Exercise $35.95 1,624 58,383 60,266 Dec 16, 2020, 07:41 PM
LIU JEAN I GC/EVP, Leg Affairs Dec 14, 2020 Sale $195.86 5,000 979,316 62,001 Dec 16, 2020, 07:41 PM
HIMES VAUGHN B Chief Technical Officer Dec 07, 2020 Option Exercise $25.36 12,761 323,646 199,590 Dec 09, 2020, 08:08 PM
HIMES VAUGHN B Chief Technical Officer Dec 07, 2020 Sale $181.76 8,000 1,454,041 198,036 Dec 09, 2020, 08:08 PM
SIEGALL CLAY B President and CEO Dec 04, 2020 Option Exercise $15.46 21,732 335,977 730,117 Dec 08, 2020, 07:33 PM
SIEGALL CLAY B President and CEO Dec 07, 2020 Option Exercise $15.46 15,723 243,078 720,265 Dec 08, 2020, 07:33 PM
SIEGALL CLAY B President and CEO Dec 04, 2020 Sale $179.43 21,732 3,899,386 715,209 Dec 08, 2020, 07:33 PM
SIEGALL CLAY B President and CEO Dec 07, 2020 Sale $181.14 15,723 2,848,122 715,209 Dec 08, 2020, 07:33 PM
SIEGALL CLAY B President and CEO Dec 03, 2020 Option Exercise $15.46 21,253 328,571 726,145 Dec 04, 2020, 07:18 PM
SIEGALL CLAY B President and CEO Dec 03, 2020 Sale $179.28 21,253 3,810,144 715,209 Dec 04, 2020, 07:18 PM
ROMP CHARLES R EVP, Commercial Dec 03, 2020 Option Exercise $39.15 7,666 300,124 51,743 Dec 03, 2020, 05:45 PM
ROMP CHARLES R EVP, Commercial Dec 01, 2020 Option Exercise $39.15 6,000 234,900 50,077 Dec 03, 2020, 05:45 PM
ROMP CHARLES R EVP, Commercial Dec 03, 2020 Sale $179.30 7,666 1,374,514 44,077 Dec 03, 2020, 05:45 PM
ROMP CHARLES R EVP, Commercial Dec 01, 2020 Sale $179.09 6,000 1,074,540 44,077 Dec 03, 2020, 05:45 PM
GRYSKA DAVID W Director Nov 19, 2020 Option Exercise $19.02 15,000 285,300 52,719 Nov 23, 2020, 08:11 PM
GRYSKA DAVID W Director Nov 19, 2020 Sale $173.70 15,000 2,605,523 44,848 Nov 23, 2020, 08:11 PM
SIMPSON TODD E Chief Financial Officer Nov 05, 2020 Sale $180.37 7,509 1,354,383 118,767 Nov 09, 2020, 07:25 PM
GRYSKA DAVID W Director Nov 05, 2020 Sale $180.60 4,500 812,700 44,848 Nov 06, 2020, 07:53 PM
ROMP CHARLES R EVP, Commercial Nov 04, 2020 Option Exercise $41.74 14,079 587,703 49,228 Nov 06, 2020, 07:34 PM
ROMP CHARLES R EVP, Commercial Nov 04, 2020 Sale $180.37 14,079 2,539,420 44,077 Nov 06, 2020, 07:34 PM
DANSEY ROGER D Chief Medical Officer Nov 04, 2020 Sale $177.00 7,661 1,356,020 110,580 Nov 05, 2020, 09:38 PM
LIPPMAN MARC E Director Nov 03, 2020 Option Exercise $35.47 62,780 2,226,870 144,432 Nov 05, 2020, 08:44 PM
LIPPMAN MARC E Director Nov 03, 2020 Sale $168.61 142,090 23,958,287 131,648 Nov 05, 2020, 08:44 PM
WELCH DANIEL G Director Nov 02, 2020 Option Exercise $25.21 49,500 1,247,653 71,098 Nov 04, 2020, 08:51 PM
WELCH DANIEL G Director Nov 02, 2020 Sale $166.13 58,750 9,760,260 56,598 Nov 04, 2020, 08:51 PM
ROMP CHARLES R EVP, Commercial Nov 03, 2020 Option Exercise $19.24 5,197 99,979 47,719 Nov 04, 2020, 08:23 PM
ROMP CHARLES R EVP, Commercial Nov 02, 2020 Sale $166.77 13,001 2,168,133 52,409 Nov 04, 2020, 08:23 PM
ROMP CHARLES R EVP, Commercial Nov 03, 2020 Sale $172.07 6,061 1,042,939 44,941 Nov 04, 2020, 08:23 PM
LIU JEAN I GC/EVP, Leg Affairs Sep 21, 2020 Option Exercise $36.77 9,954 366,019 58,642 Sep 23, 2020, 07:28 PM
LIU JEAN I GC/EVP, Leg Affairs Sep 14, 2020 Sale $170.00 11,610 1,973,700 48,688 Sep 16, 2020, 06:53 PM
HIMES VAUGHN B Chief Technical Officer Sep 09, 2020 Option Exercise $15.46 8,000 123,680 194,829 Sep 11, 2020, 06:25 PM
HIMES VAUGHN B Chief Technical Officer Sep 09, 2020 Sale $147.55 8,000 1,180,385 192,329 Sep 11, 2020, 06:25 PM
DANSEY ROGER D Chief Medical Officer Aug 31, 2020 Sale $155.69 4,611 717,905 118,792 Sep 02, 2020, 07:25 PM
HIMES VAUGHN B Chief Technical Officer Aug 31, 2020 Sale $155.69 3,585 558,163 188,625 Sep 02, 2020, 07:25 PM
LIU JEAN I GC/EVP, Leg Affairs Aug 31, 2020 Sale $155.69 3,648 567,972 62,191 Sep 02, 2020, 07:25 PM
ROMP CHARLES R EVP, Commercial Aug 31, 2020 Sale $155.69 1,133 176,401 58,497 Sep 02, 2020, 07:25 PM
SIMPSON TODD E Chief Financial Officer Sep 01, 2020 Sale $155.86 12,091 1,884,512 133,915 Sep 02, 2020, 07:24 PM
SIMPSON TODD E Chief Financial Officer Aug 31, 2020 Sale $155.69 4,187 651,891 140,489 Sep 02, 2020, 07:24 PM
SIEGALL CLAY B President and CEO Aug 31, 2020 Sale $155.69 14,351 2,234,365 719,996 Sep 02, 2020, 07:24 PM
SIEGALL CLAY B President and CEO Aug 21, 2020 Option Exercise $19.42 10,299 199,984 729,560 Aug 25, 2020, 06:35 PM
LIU JEAN I GC/EVP, Leg Affairs Aug 18, 2020 Sale $158.17 6,846 1,082,825 63,946 Aug 20, 2020, 06:58 PM
SIMPSON TODD E Chief Financial Officer Aug 18, 2020 Sale $158.17 9,262 1,464,961 142,554 Aug 20, 2020, 06:27 PM
SIEGALL CLAY B President and CEO Aug 18, 2020 Sale $158.17 27,060 4,280,053 719,261 Aug 20, 2020, 06:26 PM
ROMP CHARLES R EVP, Commercial Aug 18, 2020 Sale $158.17 4,027 636,943 59,075 Aug 20, 2020, 06:26 PM
HIMES VAUGHN B Chief Technical Officer Aug 18, 2020 Sale $158.17 8,054 1,273,893 190,414 Aug 20, 2020, 06:23 PM
DANSEY ROGER D Chief Medical Officer Aug 17, 2020 Sale $157.79 450 71,006 122,493 Aug 17, 2020, 09:40 PM
SIEGALL CLAY B President and CEO Aug 10, 2020 Option Exercise $12.00 28,475 341,700 729,955 Aug 13, 2020, 06:04 AM
SIEGALL CLAY B President and CEO Aug 10, 2020 Sale $156.74 28,475 4,463,263 718,339 Aug 13, 2020, 06:04 AM
SIMPSON TODD E Chief Financial Officer Aug 03, 2020 Sale $165.72 20,000 3,314,419 155,461 Aug 05, 2020, 07:14 PM
HIMES VAUGHN B Chief Technical Officer Jul 17, 2020 Option Exercise $15.46 8,000 123,680 199,840 Jul 21, 2020, 07:48 PM
HIMES VAUGHN B Chief Technical Officer Jul 17, 2020 Sale $179.42 8,000 1,435,363 198,640 Jul 21, 2020, 07:48 PM
SIEGALL CLAY B President and CEO Jul 08, 2020 Option Exercise $12.00 28,472 341,664 734,660 Jul 10, 2020, 06:07 PM
SIEGALL CLAY B President and CEO Jul 08, 2020 Sale $175.08 28,472 4,984,808 718,339 Jul 10, 2020, 06:07 PM
ROMP CHARLES R EVP, Commercial Jul 02, 2020 Sale $167.49 712 119,253 55,307 Jul 07, 2020, 06:34 PM
SIMPSON TODD E Chief Financial Officer Jul 01, 2020 Sale $167.58 11,573 1,939,352 173,454 Jul 02, 2020, 07:19 PM
LIU JEAN I GC/EVP, Leg Affairs Jun 19, 2020 Sale $165.00 9,877 1,629,705 63,597 Jun 22, 2020, 07:46 PM
DANSEY ROGER D Chief Medical Officer Jun 17, 2020 Sale $158.89 2,162 343,523 110,870 Jun 19, 2020, 05:54 PM
DANSEY ROGER D Chief Medical Officer Jun 15, 2020 Sale $157.15 4,984 783,236 112,608 Jun 17, 2020, 07:24 PM
DANSEY ROGER D Chief Medical Officer Jun 16, 2020 Sale $157.15 838 131,692 111,770 Jun 17, 2020, 07:24 PM
SIEGALL CLAY B President and CEO Jun 08, 2020 Option Exercise $12.00 28,472 341,664 724,939 Jun 10, 2020, 06:57 PM
SIEGALL CLAY B President and CEO Jun 08, 2020 Sale $148.77 28,472 4,235,807 718,339 Jun 10, 2020, 06:57 PM
BAKER BROS. ADVISORS LP Director May 15, 2020 Sale $160.00 1,750,000 280,000,000 43,288,836 May 19, 2020, 06:03 PM
ROMP CHARLES R EVP, Commercial May 12, 2020 Option Exercise $15.46 6,942 107,323 59,517 May 14, 2020, 06:54 PM
ROMP CHARLES R EVP, Commercial May 12, 2020 Sale $166.00 6,942 1,152,372 52,575 May 14, 2020, 06:54 PM
SIEGALL CLAY B President and CEO May 08, 2020 Option Exercise $12.00 28,472 341,664 728,603 May 12, 2020, 07:51 PM
SIEGALL CLAY B President and CEO May 08, 2020 Sale $161.01 28,472 4,584,311 718,339 May 12, 2020, 07:51 PM
ROMP CHARLES R EVP, Commercial May 08, 2020 Option Exercise $15.46 6,942 107,323 59,517 May 08, 2020, 07:54 PM
ROMP CHARLES R EVP, Commercial May 08, 2020 Sale $163.02 6,942 1,131,671 52,575 May 08, 2020, 07:54 PM
DANSEY ROGER D Chief Medical Officer May 07, 2020 Option Exercise $65.11 11,912 775,590 129,145 May 08, 2020, 07:42 PM
DANSEY ROGER D Chief Medical Officer May 07, 2020 Sale $164.50 11,912 1,959,524 117,233 May 08, 2020, 07:42 PM
BAKER BROS. ADVISORS LP Director May 07, 2020 Sale $164.41 168,244 27,660,924 45,486,837 May 08, 2020, 05:47 PM
BAKER BROS. ADVISORS LP Director May 06, 2020 Sale $165.04 390,072 64,379,426 45,814,543 May 08, 2020, 05:47 PM
BAKER BROS. ADVISORS LP Director May 08, 2020 Sale $158.50 500,000 79,250,000 44,891,148 May 08, 2020, 05:47 PM
WELCH DANIEL G Director May 06, 2020 Sale $164.79 15,000 2,471,919 62,222 May 07, 2020, 07:59 PM
WELCH DANIEL G Director May 05, 2020 Sale $166.73 20,000 3,334,641 86,958 May 07, 2020, 07:59 PM
SIEGALL CLAY B President and CEO May 06, 2020 Sale $165.23 25,402 4,197,062 739,795 May 07, 2020, 07:59 PM
SIEGALL CLAY B President and CEO May 05, 2020 Sale $166.08 24,598 4,085,341 761,170 May 07, 2020, 07:59 PM
ROMP CHARLES R EVP, Commercial May 05, 2020 Sale $166.18 5,056 840,225 54,575 May 07, 2020, 07:59 PM
AKKARAJU SRINIVAS Director May 05, 2020 Option Exercise $20.06 8,500 170,510 48,668 May 07, 2020, 07:58 PM
AKKARAJU SRINIVAS Director May 05, 2020 Sale $167.26 8,500 1,421,710 40,168 May 07, 2020, 07:58 PM
SIMPSON TODD E Chief Financial Officer May 05, 2020 Option Exercise $22.15 39,059 865,277 188,563 May 06, 2020, 06:32 PM
SIMPSON TODD E Chief Financial Officer May 04, 2020 Option Exercise $12.00 14,167 170,004 175,863 May 06, 2020, 06:32 PM
SIMPSON TODD E Chief Financial Officer May 05, 2020 Sale $162.94 26,867 4,377,596 175,063 May 06, 2020, 06:32 PM
SIMPSON TODD E Chief Financial Officer May 04, 2020 Sale $147.00 14,167 2,082,563 161,696 May 06, 2020, 06:32 PM
LIPPMAN MARC E Director May 04, 2020 Sale $152.03 1,000 152,030 130,313 May 06, 2020, 06:19 PM
BAKER BROS. ADVISORS LP Director Apr 23, 2020 Option Exercise $12.76 35,000 446,600 45,860,149 Apr 24, 2020, 04:25 PM
ROMP CHARLES R EVP, Commercial Apr 19, 2020 Option Exercise $139.91 326 45,612 56,809 Apr 22, 2020, 06:12 AM
LIU JEAN I GC/EVP, Leg Afairs Apr 19, 2020 Option Exercise $139.92 645 90,246 73,474 Apr 22, 2020, 06:11 AM
HIMES VAUGHN B Chief Technical Officer Apr 21, 2020 Option Exercise $139.92 920 128,724 191,582 Apr 21, 2020, 09:59 PM
DANSEY ROGER D Chief Medical Officer Apr 21, 2020 Option Exercise $139.92 1,159 162,164 117,233 Apr 21, 2020, 09:58 PM
SIEGALL CLAY B President and CEO Apr 21, 2020 Option Exercise $139.92 3,023 422,969 768,339 Apr 21, 2020, 09:57 PM
SIMPSON TODD E Chief Financial Officer Apr 21, 2020 Option Exercise $139.92 570 79,752 161,696 Apr 21, 2020, 09:57 PM
SIEGALL CLAY B President and CEO Apr 08, 2020 Option Exercise $12.00 28,472 341,664 779,866 Apr 10, 2020, 07:31 PM
SIEGALL CLAY B President and CEO Apr 08, 2020 Sale $120.01 28,472 3,416,814 758,784 Apr 10, 2020, 07:31 PM
SIEGALL CLAY B President and CEO Mar 09, 2020 Option Exercise $12.00 28,472 341,664 768,581 Mar 11, 2020, 06:51 PM
SIEGALL CLAY B President and CEO Mar 09, 2020 Sale $110.09 28,472 3,134,578 758,784 Mar 11, 2020, 06:51 PM
HIMES VAUGHN B Chief Technical Officer Mar 06, 2020 Option Exercise $13.51 8,000 108,117 193,172 Mar 10, 2020, 08:12 PM
HIMES VAUGHN B Chief Technical Officer Mar 06, 2020 Sale $114.91 8,000 919,292 188,874 Mar 10, 2020, 08:12 PM
DANSEY ROGER D Chief Medical Officer Feb 18, 2020 Sale $116.33 350 40,716 107,659 Feb 20, 2020, 05:33 PM
SIEGALL CLAY B President and CEO Feb 10, 2020 Option Exercise $12.00 28,472 341,664 768,723 Feb 12, 2020, 05:38 PM
SIEGALL CLAY B President and CEO Feb 10, 2020 Sale $114.61 28,472 3,263,110 758,784 Feb 12, 2020, 05:38 PM
DANSEY ROGER D Chief Medical Officer Feb 03, 2020 Sale $108.51 727 78,887 108,009 Feb 05, 2020, 06:08 PM
SIEGALL CLAY B President and CEO Jan 08, 2020 Option Exercise $12.00 28,472 341,664 785,937 Jan 10, 2020, 07:08 PM
SIEGALL CLAY B President and CEO Jan 08, 2020 Sale $111.32 28,472 3,169,433 758,784 Jan 10, 2020, 07:08 PM
WELCH DANIEL G Director Jan 07, 2020 Option Exercise $12.76 17,500 223,300 90,263 Jan 09, 2020, 08:32 PM
DANSEY ROGER D Chief Medical Officer Dec 16, 2019 Sale $114.07 2,000 228,140 101,146 Dec 17, 2019, 06:48 PM
SIEGALL CLAY B President and CEO Dec 09, 2019 Option Exercise $12.00 28,472 341,664 773,011 Dec 10, 2019, 07:15 PM
SIEGALL CLAY B President and CEO Dec 09, 2019 Sale $114.56 28,472 3,261,641 755,684 Dec 10, 2019, 07:15 PM
HIMES VAUGHN B Chief Technical Officer Dec 06, 2019 Option Exercise $12.00 8,000 96,000 195,518 Dec 10, 2019, 07:14 PM
HIMES VAUGHN B Chief Technical Officer Dec 06, 2019 Sale $117.16 8,000 937,265 188,567 Dec 10, 2019, 07:14 PM
DANSEY ROGER D Chief Medical Officer Nov 25, 2019 Option Exercise $65.11 5,000 325,550 108,146 Nov 27, 2019, 05:32 PM
DANSEY ROGER D Chief Medical Officer Nov 25, 2019 Sale $121.48 5,000 607,390 103,146 Nov 27, 2019, 05:32 PM
AKKARAJU SRINIVAS Director Nov 21, 2019 Option Exercise $19.02 17,500 332,850 52,726 Nov 22, 2019, 06:35 PM
AKKARAJU SRINIVAS Director Nov 21, 2019 Sale $119.78 17,500 2,096,120 40,168 Nov 22, 2019, 06:35 PM
DANSEY ROGER D Chief Medical Officer Nov 18, 2019 Option Exercise $65.11 5,000 325,550 108,146 Nov 20, 2019, 06:45 PM
DANSEY ROGER D Chief Medical Officer Nov 18, 2019 Sale $116.00 5,000 580,000 103,146 Nov 20, 2019, 06:45 PM
LIPPMAN MARC E Director Nov 18, 2019 Option Exercise $15.89 35,000 556,150 148,813 Nov 20, 2019, 06:41 PM
LIPPMAN MARC E Director Nov 18, 2019 Sale $115.80 35,000 4,053,000 131,313 Nov 20, 2019, 06:41 PM
SIEGALL CLAY B President and CEO Nov 08, 2019 Option Exercise $12.00 28,472 341,664 776,483 Nov 12, 2019, 06:24 PM
SIEGALL CLAY B President and CEO Nov 08, 2019 Sale $107.61 28,472 3,063,816 755,684 Nov 12, 2019, 06:24 PM
SIEGALL CLAY B President and CEO Oct 08, 2019 Option Exercise $12.00 28,472 341,664 770,104 Oct 10, 2019, 06:55 PM
SIEGALL CLAY B President and CEO Oct 08, 2019 Sale $82.47 28,472 2,348,062 755,684 Oct 10, 2019, 06:55 PM
GRYSKA DAVID W Director Oct 01, 2019 Option Exercise $15.89 5,000 79,450 50,513 Oct 03, 2019, 07:38 PM
GRYSKA DAVID W Director Oct 01, 2019 Sale $85.09 5,000 425,450 48,013 Oct 03, 2019, 07:38 PM
SIMPSON TODD E Chief Financial Officer Sep 30, 2019 Sale $85.00 15,000 1,275,000 157,567 Oct 02, 2019, 06:12 PM
LIU JEAN I GC/EVP, Leg Affairs Sep 30, 2019 Sale $86.00 7,432 639,152 74,404 Oct 02, 2019, 06:10 PM
DANSEY ROGER D Chief Medical Officer Sep 25, 2019 Sale $73.80 3,000 221,415 103,636 Sep 27, 2019, 06:12 PM
SIEGALL CLAY B President and CEO Sep 09, 2019 Option Exercise $12.00 28,472 341,664 774,374 Sep 10, 2019, 07:29 PM
SIEGALL CLAY B President and CEO Sep 09, 2019 Sale $68.33 28,472 1,945,531 755,684 Sep 10, 2019, 07:29 PM
SIEGALL CLAY B See Remarks Sep 03, 2019 Sale $70.80 9,693 686,257 755,684 Sep 04, 2019, 09:46 PM
HIMES VAUGHN B See Remarks Aug 30, 2019 Option Exercise $12.00 8,000 96,000 201,210 Sep 04, 2019, 09:45 PM
HIMES VAUGHN B See Remarks Sep 03, 2019 Sale $70.80 5,692 402,990 191,396 Sep 04, 2019, 09:45 PM
HIMES VAUGHN B See Remarks Aug 30, 2019 Sale $72.86 8,000 582,859 193,923 Sep 04, 2019, 09:45 PM
DANSEY ROGER D See Remarks Sep 03, 2019 Sale $70.80 922 65,277 106,317 Sep 04, 2019, 09:43 PM
SIMPSON TODD E See Remarks Sep 03, 2019 Sale $70.80 2,092 148,112 172,567 Sep 04, 2019, 09:42 PM
SIMPSON TODD E Chief Financial Officer Aug 28, 2019 Sale $73.21 5,909 432,624 153,371 Aug 30, 2019, 04:36 PM
SIEGALL CLAY B President and CEO Aug 28, 2019 Sale $73.21 28,951 2,119,636 717,343 Aug 30, 2019, 04:35 PM
LIU JEAN I GC/EVP, Leg Affairs Aug 28, 2019 Sale $73.21 6,013 440,242 60,904 Aug 30, 2019, 04:35 PM
HIMES VAUGHN B Chief Technical Officer Aug 28, 2019 Sale $73.21 6,836 500,496 175,197 Aug 30, 2019, 04:35 PM
SIMPSON TODD E Chief Financial Officer Aug 20, 2019 Sale $80.00 12,500 1,000,000 159,280 Aug 22, 2019, 05:49 PM
LIU JEAN I GC/EVP, Leg Affairs Aug 20, 2019 Sale $80.00 3,716 297,280 66,917 Aug 22, 2019, 05:47 PM
SIEGALL CLAY B President and CEO Aug 08, 2019 Option Exercise $12.16 20,149 245,012 756,192 Aug 09, 2019, 05:06 PM
SIEGALL CLAY B President and CEO Aug 08, 2019 Sale $76.52 20,149 1,541,827 746,294 Aug 09, 2019, 05:06 PM
LIU JEAN I GC/EVP, Leg Affairs Aug 06, 2019 Sale $75.00 3,716 278,700 70,633 Aug 08, 2019, 05:42 PM
GRYSKA DAVID W Director Jul 17, 2019 Option Exercise $12.76 5,000 63,800 53,013 Jul 19, 2019, 06:20 PM
GRYSKA DAVID W Director Jul 17, 2019 Sale $75.00 5,000 375,000 48,013 Jul 19, 2019, 06:20 PM
SIEGALL CLAY B President and CEO Jul 08, 2019 Option Exercise $12.16 20,148 245,000 761,011 Jul 10, 2019, 06:57 PM
SIEGALL CLAY B President and CEO Jul 08, 2019 Sale $66.89 20,148 1,347,664 746,294 Jul 10, 2019, 06:57 PM
HIMES VAUGHN B Chief Technical Officer Jun 24, 2019 Option Exercise $42.51 4,704 199,970 182,033 Jun 26, 2019, 06:26 PM
DANSEY ROGER D Chief Medical Officer Jun 17, 2019 Sale $68.60 5,416 371,538 77,593 Jun 19, 2019, 06:43 PM
SIEGALL CLAY B President and CEO Jun 10, 2019 Option Exercise $12.16 20,148 245,000 760,119 Jun 12, 2019, 05:51 PM
SIEGALL CLAY B President and CEO Jun 10, 2019 Sale $69.05 20,148 1,391,175 749,169 Jun 12, 2019, 05:51 PM
HIMES VAUGHN B Chief Technical Officer May 31, 2019 Option Exercise $12.00 8,000 96,000 185,329 Jun 04, 2019, 06:28 PM
HIMES VAUGHN B Chief Technical Officer May 31, 2019 Sale $65.94 8,000 527,485 179,889 Jun 04, 2019, 06:28 PM
SIEGALL CLAY B President and CEO May 08, 2019 Option Exercise $12.16 15,324 186,340 762,600 May 10, 2019, 04:39 PM
SIEGALL CLAY B President and CEO May 09, 2019 Option Exercise $12.16 4,824 58,660 752,063 May 10, 2019, 04:39 PM
SIEGALL CLAY B President and CEO May 08, 2019 Sale $68.26 15,324 1,046,066 749,169 May 10, 2019, 04:39 PM
SIEGALL CLAY B President and CEO May 09, 2019 Sale $67.43 4,824 325,301 749,169 May 10, 2019, 04:39 PM
BAKER BROS. ADVISORS LP Director Apr 29, 2019 Option Exercise $8.38 20,000 167,600 45,839,686 May 01, 2019, 04:59 PM
SIEGALL CLAY B President and CEO Apr 08, 2019 Option Exercise $12.16 20,148 245,000 757,976 Apr 10, 2019, 04:39 PM
SIEGALL CLAY B President and CEO Apr 08, 2019 Sale $79.22 20,148 1,596,100 749,169 Apr 10, 2019, 04:39 PM
SIMPSON TODD E Chief Financial Officer Apr 05, 2019 Sale $78.00 12,500 975,000 182,217 Apr 09, 2019, 08:35 PM
GRYSKA DAVID W Director Apr 01, 2019 Option Exercise $12.76 5,000 63,800 50,050 Apr 03, 2019, 08:57 PM
GRYSKA DAVID W Director Apr 01, 2019 Sale $73.41 5,000 367,030 45,256 Apr 03, 2019, 08:57 PM
SIEGALL CLAY B President and CEO Mar 18, 2019 Option Exercise $12.08 16,556 199,988 749,169 Mar 20, 2019, 06:34 PM
SIEGALL CLAY B President and CEO Mar 08, 2019 Option Exercise $12.16 20,148 245,000 745,259 Mar 12, 2019, 07:34 PM
SIEGALL CLAY B President and CEO Mar 08, 2019 Sale $69.19 20,148 1,394,094 732,613 Mar 12, 2019, 07:34 PM
HIMES VAUGHN B Chief Technical Officer Mar 08, 2019 Option Exercise $12.00 8,000 96,000 185,329 Mar 12, 2019, 07:31 PM
HIMES VAUGHN B Chief Technical Officer Mar 08, 2019 Sale $68.72 8,000 549,746 180,672 Mar 12, 2019, 07:31 PM
SIMPSON TODD E Chief Financial Officer Mar 04, 2019 Sale $75.00 10,000 750,000 184,280 Mar 06, 2019, 06:58 PM
SIEGALL CLAY B See Remarks Feb 08, 2019 Option Exercise $12.16 20,148 245,000 740,690 Feb 12, 2019, 06:25 PM
SIEGALL CLAY B See Remarks Feb 08, 2019 Sale $65.17 20,148 1,313,126 732,613 Feb 12, 2019, 06:25 PM
GRYSKA DAVID W Director Jan 08, 2019 Option Exercise $12.76 5,000 63,800 50,050 Jan 10, 2019, 09:09 PM
GRYSKA DAVID W Director Jan 08, 2019 Sale $65.04 5,000 325,200 45,050 Jan 10, 2019, 09:09 PM
SIEGALL CLAY B President and CEO Jan 08, 2019 Option Exercise $12.16 20,148 245,000 739,713 Jan 10, 2019, 08:27 PM
SIEGALL CLAY B President and CEO Jan 08, 2019 Sale $65.73 20,148 1,324,237 732,613 Jan 10, 2019, 08:27 PM
SIEGALL CLAY B President and CEO Dec 10, 2018 Option Exercise $12.16 20,148 245,000 745,761 Dec 12, 2018, 07:31 PM
SIEGALL CLAY B President and CEO Dec 10, 2018 Sale $59.74 20,148 1,203,545 732,613 Dec 12, 2018, 07:31 PM
HIMES VAUGHN B Chief Technical Officer Nov 30, 2018 Option Exercise $12.00 5,000 60,000 177,329 Dec 04, 2018, 07:37 PM
HIMES VAUGHN B Chief Technical Officer Nov 30, 2018 Sale $62.14 5,000 310,718 172,729 Dec 04, 2018, 07:37 PM
Cline Darren S EVP, Commercial Nov 29, 2018 Sale $62.88 7,000 440,160 72,556 Nov 30, 2018, 06:32 PM
Cline Darren S EVP, Commercial Nov 21, 2018 Sale $56.68 4,167 236,204 79,556 Nov 21, 2018, 06:42 PM
SIEGALL CLAY B President and CEO Nov 08, 2018 Option Exercise $12.16 20,148 245,000 746,091 Nov 09, 2018, 05:54 PM
SIEGALL CLAY B President and CEO Nov 08, 2018 Sale $61.54 20,148 1,239,873 732,613 Nov 09, 2018, 05:54 PM
AKKARAJU SRINIVAS Director Oct 30, 2018 Option Exercise $8.38 5,000 41,900 37,205 Nov 01, 2018, 05:55 PM
SIEGALL CLAY B President and CEO Oct 08, 2018 Option Exercise $12.16 20,148 245,000 746,550 Oct 09, 2018, 08:13 PM
SIEGALL CLAY B President and CEO Oct 08, 2018 Sale $77.39 20,148 1,559,231 732,613 Oct 09, 2018, 08:13 PM
SIEGALL CLAY B President and CEO Sep 17, 2018 Option Exercise $12.16 20,148 245,000 742,544 Sep 19, 2018, 06:36 PM
SIEGALL CLAY B President and CEO Sep 17, 2018 Sale $76.84 20,148 1,548,196 732,613 Sep 19, 2018, 06:36 PM
HIMES VAUGHN B Chief Technical Officer Sep 07, 2018 Option Exercise $12.00 5,000 60,000 182,329 Sep 11, 2018, 07:26 PM
HIMES VAUGHN B Chief Technical Officer Sep 07, 2018 Sale $76.99 5,000 384,962 180,929 Sep 11, 2018, 07:26 PM
SIMPSON TODD E Chief Financial Officer Aug 27, 2018 Sale $74.23 5,427 402,856 173,565 Aug 29, 2018, 07:40 PM
SIEGALL CLAY B President and CEO Aug 27, 2018 Sale $74.23 25,514 1,893,950 636,632 Aug 29, 2018, 07:39 PM
LIU JEAN I GC/EVP, Leg Affairs Aug 27, 2018 Sale $74.23 4,123 306,058 56,741 Aug 29, 2018, 07:37 PM
HIMES VAUGHN B Chief Technical Officer Aug 27, 2018 Sale $74.23 5,530 410,502 159,376 Aug 29, 2018, 07:35 PM
Cline Darren S EVP, Commercial Aug 27, 2018 Sale $74.23 4,784 355,125 65,079 Aug 29, 2018, 07:32 PM
SIEGALL CLAY B President and CEO Aug 21, 2018 Sale $74.95 25,000 1,873,750 662,146 Aug 23, 2018, 08:01 PM
SIEGALL CLAY B See Remarks Aug 09, 2018 Option Exercise $11.09 18,831 208,836 703,857 Aug 13, 2018, 04:47 PM
SIEGALL CLAY B See Remarks Aug 09, 2018 Sale $72.71 18,831 1,369,153 687,146 Aug 13, 2018, 04:47 PM
LIPPMAN MARC E Director Jul 31, 2018 Sale $69.25 7,400 512,450 128,350 Aug 02, 2018, 08:00 PM
SIEGALL CLAY B President and CEO Jul 09, 2018 Option Exercise $11.09 18,832 208,847 702,356 Jul 11, 2018, 08:28 PM
SIEGALL CLAY B President and CEO Jul 09, 2018 Sale $69.07 18,832 1,300,770 687,146 Jul 11, 2018, 08:28 PM
Cline Darren S EVP, Commercial Jun 12, 2018 Option Exercise $29.14 10,086 293,910 79,831 Jun 14, 2018, 06:31 PM
Cline Darren S EVP, Commercial Jun 12, 2018 Sale $69.00 12,054 831,688 71,831 Jun 14, 2018, 06:31 PM
SIEGALL CLAY B President and CEO Jun 08, 2018 Option Exercise $11.09 18,832 208,847 705,278 Jun 12, 2018, 07:34 PM
SIEGALL CLAY B President and CEO Jun 08, 2018 Sale $65.12 18,832 1,226,341 687,146 Jun 12, 2018, 07:34 PM
HIMES VAUGHN B Chief Technical Officer May 31, 2018 Option Exercise $12.00 5,000 60,000 169,906 Jun 04, 2018, 07:11 PM
HIMES VAUGHN B Chief Technical Officer May 31, 2018 Sale $58.47 5,000 292,365 168,906 Jun 04, 2018, 07:11 PM
BAKER BROS. ADVISORS LP Director May 18, 2018 Option Exercise $56.77 7,400 420,098 45,829,686 May 18, 2018, 04:25 PM
SIEGALL CLAY B President and CEO May 09, 2018 Option Exercise $11.09 18,832 208,847 694,922 May 11, 2018, 08:01 PM
SIEGALL CLAY B President and CEO May 09, 2018 Sale $54.97 18,832 1,035,114 687,146 May 11, 2018, 08:01 PM
Cline Darren S EVP, Commercial May 09, 2018 Option Exercise $16.20 9,000 145,790 80,831 May 11, 2018, 07:59 PM
Cline Darren S EVP, Commercial May 09, 2018 Sale $55.33 9,000 497,983 71,831 May 11, 2018, 07:59 PM
BAKER BROS. ADVISORS LP Director May 07, 2018 Buy $53.70 129,715 6,966,305 45,699,587 May 08, 2018, 05:17 PM
BAKER BROS. ADVISORS LP Director May 04, 2018 Buy $52.68 204,537 10,775,582 45,569,872 May 08, 2018, 05:17 PM
BAKER BROS. ADVISORS LP Director May 08, 2018 Buy $54.02 126,399 6,828,339 45,825,986 May 08, 2018, 05:17 PM
Cline Darren S EVP, Commercial May 03, 2018 Sale $53.81 4,000 215,238 71,831 May 07, 2018, 07:08 PM
BAKER BROS. ADVISORS LP Director May 01, 2018 Option Exercise $10.08 20,000 201,600 44,988,471 May 02, 2018, 06:05 PM
BAKER BROS. ADVISORS LP Director May 02, 2018 Buy $52.57 69,947 3,676,836 45,365,335 May 02, 2018, 06:05 PM
BAKER BROS. ADVISORS LP Director May 01, 2018 Buy $51.36 306,917 15,764,736 45,295,388 May 02, 2018, 06:05 PM
BAKER BROS. ADVISORS LP Director Apr 30, 2018 Buy $51.06 623,136 31,816,925 44,978,471 May 02, 2018, 06:05 PM
SIEGALL CLAY B President and CEO Apr 09, 2018 Option Exercise $11.09 18,832 208,847 705,978 Apr 11, 2018, 08:38 PM
SIEGALL CLAY B President and CEO Apr 09, 2018 Sale $50.52 18,832 951,393 687,146 Apr 11, 2018, 08:38 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Mar 20, 2018 Option Exercise $14.15 31,039 439,134 201,973 Mar 22, 2018, 07:04 PM
HIMES VAUGHN B See Remarks Mar 15, 2018 Option Exercise $12.00 5,000 60,000 169,906 Mar 19, 2018, 07:35 PM
HIMES VAUGHN B See Remarks Mar 15, 2018 Sale $58.12 5,000 290,604 165,106 Mar 19, 2018, 07:35 PM
SIEGALL CLAY B President and CEO Mar 09, 2018 Option Exercise $11.09 18,832 208,847 701,214 Mar 13, 2018, 08:43 PM
SIEGALL CLAY B President and CEO Mar 09, 2018 Sale $57.32 18,832 1,079,436 687,146 Mar 13, 2018, 08:43 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Mar 05, 2018 Option Exercise $8.96 10,457 93,695 178,134 Mar 07, 2018, 08:25 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Mar 05, 2018 Sale $52.83 10,457 552,452 170,934 Mar 07, 2018, 08:25 PM
WELCH DANIEL G Director Feb 13, 2018 Option Exercise $9.39 16,881 158,463 66,100 Feb 15, 2018, 09:21 PM
SIEGALL CLAY B President and CEO Feb 09, 2018 Option Exercise $11.09 18,832 208,847 697,546 Feb 13, 2018, 08:19 PM
SIEGALL CLAY B President and CEO Feb 09, 2018 Sale $49.75 18,832 936,818 687,146 Feb 13, 2018, 08:19 PM
Cline Darren S EVP, Commercial Feb 05, 2018 Option Exercise $55.58 1,399 77,756 75,831 Feb 07, 2018, 08:17 PM
BAKER BROS. ADVISORS LP Director Feb 01, 2018 Buy $52.00 3,456,543 179,740,236 44,355,335 Feb 05, 2018, 04:00 PM
BAKER BROS. ADVISORS LP Director Feb 01, 2018 Buy $52.00 389,610 20,259,720 5,278,174 Feb 05, 2018, 04:00 PM
SIEGALL CLAY B President and CEO Jan 11, 2018 Option Exercise $11.09 18,832 208,847 697,716 Jan 16, 2018, 08:08 PM
SIEGALL CLAY B President and CEO Jan 11, 2018 Sale $51.71 18,832 973,873 687,146 Jan 16, 2018, 08:08 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Jan 11, 2018 Option Exercise $11.06 19,416 214,705 170,934 Jan 16, 2018, 08:04 PM
SIEGALL CLAY B President and CEO Dec 11, 2017 Option Exercise $11.09 18,832 208,847 698,933 Dec 13, 2017, 08:50 PM
SIEGALL CLAY B President and CEO Dec 11, 2017 Sale $55.40 18,832 1,043,329 687,146 Dec 13, 2017, 08:50 PM
LIU JEAN I GC/EVP, Leg Affairs Dec 04, 2017 Option Exercise $59.55 7,536 448,769 60,864 Dec 06, 2017, 08:06 PM
DOBMEIER ERIC Chief Operating Officer Dec 04, 2017 Option Exercise $32.00 6,165 197,300 121,153 Dec 06, 2017, 08:04 PM
DOBMEIER ERIC Chief Operating Officer Dec 04, 2017 Sale $58.75 3,729 219,092 117,424 Dec 06, 2017, 08:04 PM
HIMES VAUGHN B Chief Technical Officer Nov 30, 2017 Option Exercise $12.16 10,000 121,573 172,306 Dec 04, 2017, 07:54 PM
HIMES VAUGHN B Chief Technical Officer Nov 30, 2017 Sale $59.97 10,000 599,729 164,906 Dec 04, 2017, 07:54 PM
LIPPMAN MARC E Director Nov 15, 2017 Sale $58.07 3,000 174,224 132,050 Nov 17, 2017, 08:47 PM
DOBMEIER ERIC Chief Operating Officer Nov 17, 2017 Option Exercise $26.10 10,000 261,000 127,424 Nov 17, 2017, 08:45 PM
DOBMEIER ERIC Chief Operating Officer Nov 16, 2017 Option Exercise $20.23 15,400 311,617 125,913 Nov 17, 2017, 08:45 PM
DOBMEIER ERIC Chief Operating Officer Nov 15, 2017 Option Exercise $15.46 9,600 148,416 127,024 Nov 17, 2017, 08:45 PM
DOBMEIER ERIC Chief Operating Officer Nov 17, 2017 Sale $59.13 10,000 591,250 117,424 Nov 17, 2017, 08:45 PM
DOBMEIER ERIC Chief Operating Officer Nov 16, 2017 Sale $57.96 15,400 892,637 117,424 Nov 17, 2017, 08:45 PM
DOBMEIER ERIC Chief Operating Officer Nov 15, 2017 Sale $57.80 9,600 554,837 117,424 Nov 17, 2017, 08:45 PM
SIEGALL CLAY B President and CEO Nov 10, 2017 Option Exercise $11.09 18,832 208,847 704,255 Nov 14, 2017, 07:40 PM
SIEGALL CLAY B President and CEO Nov 10, 2017 Sale $58.00 18,832 1,092,193 687,146 Nov 14, 2017, 07:40 PM
SIMPSON TODD E Chief Financial Officer Nov 01, 2017 Sale $60.91 39,385 2,398,915 179,526 Nov 03, 2017, 05:42 PM
SIEGALL CLAY B President and CEO Oct 11, 2017 Option Exercise $11.09 18,832 208,847 694,045 Oct 13, 2017, 08:58 PM
SIEGALL CLAY B President and CEO Oct 11, 2017 Sale $61.18 18,832 1,152,234 687,146 Oct 13, 2017, 08:58 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Oct 05, 2017 Option Exercise $11.52 17,816 205,253 151,518 Oct 10, 2017, 06:42 PM
SIEGALL CLAY B President and CEO Sep 26, 2017 Option Exercise $11.09 9,017 99,999 687,146 Sep 28, 2017, 06:15 PM
SIEGALL CLAY B President and CEO Sep 11, 2017 Option Exercise $11.09 18,832 208,847 695,246 Sep 12, 2017, 07:34 PM
SIEGALL CLAY B President and CEO Sep 11, 2017 Sale $53.49 18,832 1,007,257 678,129 Sep 12, 2017, 07:34 PM
HIMES VAUGHN B Chief Technical Officer Sep 08, 2017 Option Exercise $11.23 10,000 112,329 171,742 Sep 12, 2017, 07:32 PM
HIMES VAUGHN B Chief Technical Officer Sep 08, 2017 Sale $53.22 10,000 532,190 164,906 Sep 12, 2017, 07:32 PM
SIMPSON TODD E Chief Financial Officer Sep 06, 2017 Sale $52.00 9,638 501,176 218,377 Sep 08, 2017, 07:34 PM
Cline Darren S EVP, Commercial Sep 06, 2017 Option Exercise $15.93 10,048 160,115 82,254 Sep 08, 2017, 07:32 PM
Cline Darren S EVP, Commercial Sep 06, 2017 Sale $51.94 5,024 260,967 77,230 Sep 08, 2017, 07:32 PM
DOBMEIER ERIC Chief Operating Officer Aug 31, 2017 Option Exercise $15.46 25,000 386,500 142,424 Sep 05, 2017, 07:25 PM
DOBMEIER ERIC Chief Operating Officer Aug 31, 2017 Sale $52.24 25,000 1,305,892 117,424 Sep 05, 2017, 07:25 PM
Cline Darren S EVP, Commercial Aug 31, 2017 Option Exercise $18.46 2,907 53,663 79,775 Sep 05, 2017, 07:23 PM
Cline Darren S EVP, Commercial Aug 31, 2017 Sale $52.51 7,569 397,466 76,868 Sep 05, 2017, 07:23 PM
SIMPSON TODD E Chief Financial Officer Aug 28, 2017 Sale $47.89 4,937 236,455 228,015 Aug 30, 2017, 07:27 PM
SIEGALL CLAY B President and CEO Aug 28, 2017 Sale $47.89 25,506 1,221,597 678,129 Aug 30, 2017, 07:25 PM
HIMES VAUGHN B Chief Technical Officer Aug 28, 2017 Sale $47.89 6,377 305,423 164,906 Aug 30, 2017, 07:24 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Aug 28, 2017 Sale $47.89 8,502 407,199 133,702 Aug 30, 2017, 07:23 PM
DOBMEIER ERIC Chief Operating Officer Aug 28, 2017 Sale $47.89 5,343 255,900 117,424 Aug 30, 2017, 07:21 PM
Cline Darren S EVP, Commercial Aug 28, 2017 Sale $47.89 1,788 85,635 76,868 Aug 30, 2017, 07:18 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Aug 24, 2017 Option Exercise $10.29 10,000 102,900 152,204 Aug 25, 2017, 07:52 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Aug 24, 2017 Sale $47.54 10,000 475,414 142,204 Aug 25, 2017, 07:52 PM
SIEGALL CLAY B President and CEO Aug 07, 2017 Option Exercise $10.29 10,413 107,150 646,848 Aug 09, 2017, 06:58 PM
SIEGALL CLAY B President and CEO Aug 07, 2017 Sale $48.91 10,413 509,300 636,435 Aug 09, 2017, 06:58 PM
Cline Darren S EVP, Commercial Aug 07, 2017 Option Exercise $18.46 6,000 110,760 67,656 Aug 09, 2017, 06:52 PM
Cline Darren S EVP, Commercial Aug 07, 2017 Sale $49.19 6,000 295,110 61,656 Aug 09, 2017, 06:52 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Jul 27, 2017 Option Exercise $10.29 10,000 102,900 125,204 Jul 31, 2017, 07:15 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Jul 27, 2017 Sale $54.54 10,000 545,361 115,204 Jul 31, 2017, 07:15 PM
SIEGALL CLAY B President and CEO Jul 05, 2017 Option Exercise $10.29 10,423 107,253 644,629 Jul 07, 2017, 07:20 PM
SIEGALL CLAY B President and CEO Jul 05, 2017 Sale $51.98 10,423 541,807 636,435 Jul 07, 2017, 07:20 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Jun 22, 2017 Option Exercise $10.29 10,000 102,900 125,204 Jun 26, 2017, 06:25 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Jun 22, 2017 Sale $64.01 10,000 640,058 115,304 Jun 26, 2017, 06:25 PM
SIEGALL CLAY B President and CEO Jun 05, 2017 Option Exercise $10.29 10,423 107,253 646,195 Jun 07, 2017, 07:24 PM
SIEGALL CLAY B President and CEO Jun 05, 2017 Sale $65.21 10,423 679,698 636,435 Jun 07, 2017, 07:24 PM
HIMES VAUGHN B Chief Technical Officer May 31, 2017 Option Exercise $9.23 10,000 92,300 160,683 Jun 02, 2017, 07:08 PM
HIMES VAUGHN B Chief Technical Officer May 31, 2017 Sale $62.59 10,000 625,922 151,283 Jun 02, 2017, 07:08 PM
BAKER BROS. ADVISORS LP Director May 19, 2017 Option Exercise $66.60 3,700 246,420 40,898,792 May 23, 2017, 05:11 PM
BAKER BROS. ADVISORS LP Director May 19, 2017 Option Exercise $66.60 3,700 246,420 4,888,564 May 23, 2017, 05:11 PM
BAKER BROS. ADVISORS LP Director May 15, 2017 Option Exercise $10.20 20,000 204,000 40,895,092 May 17, 2017, 05:26 PM
SIEGALL CLAY B President and CEO May 05, 2017 Option Exercise $10.26 14,462 148,450 645,765 May 09, 2017, 07:42 PM
SIEGALL CLAY B President and CEO May 05, 2017 Sale $61.74 14,462 892,897 636,435 May 09, 2017, 07:42 PM
SIEGALL CLAY B President and CEO Apr 05, 2017 Option Exercise $10.26 14,465 148,481 646,858 Apr 06, 2017, 08:10 PM
SIEGALL CLAY B President and CEO Apr 05, 2017 Sale $62.99 14,465 911,111 636,435 Apr 06, 2017, 08:10 PM
HIMES VAUGHN B Chief Technical Officer Mar 31, 2017 Option Exercise $9.23 10,000 92,300 161,283 Apr 04, 2017, 05:48 PM
HIMES VAUGHN B Chief Technical Officer Mar 31, 2017 Sale $62.75 10,000 627,527 151,283 Apr 04, 2017, 05:48 PM
SIEGALL CLAY B President and CEO Mar 06, 2017 Option Exercise $10.26 14,465 148,481 646,858 Mar 08, 2017, 07:22 PM
SIEGALL CLAY B President and CEO Mar 06, 2017 Sale $68.04 14,465 984,259 636,435 Mar 08, 2017, 07:22 PM
SIEGALL CLAY B President and CEO Feb 06, 2017 Option Exercise $10.26 14,465 148,481 646,758 Feb 08, 2017, 05:29 PM
SIEGALL CLAY B President and CEO Feb 06, 2017 Sale $61.54 14,465 890,164 636,435 Feb 08, 2017, 05:29 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Jan 25, 2017 Option Exercise $10.29 5,000 51,450 114,837 Jan 26, 2017, 07:41 PM
SIEGALL CLAY B President and CEO Jan 06, 2017 Option Exercise $10.26 14,465 148,481 646,888 Jan 10, 2017, 06:11 PM
SIEGALL CLAY B President and CEO Jan 06, 2017 Sale $57.89 14,465 837,425 638,835 Jan 10, 2017, 06:11 PM
Cline Darren S EVP, Commercial Dec 16, 2016 Option Exercise $16.41 3,100 50,871 61,604 Dec 20, 2016, 07:48 PM
Cline Darren S EVP, Commercial Dec 13, 2016 Option Exercise $24.45 12,761 311,968 65,743 Dec 15, 2016, 07:26 PM
Cline Darren S EVP, Commercial Dec 13, 2016 Sale $63.38 10,000 633,834 58,504 Dec 15, 2016, 07:26 PM
HIMES VAUGHN B Chief Technical Officer Dec 12, 2016 Option Exercise $16.89 15,632 263,980 151,011 Dec 14, 2016, 05:35 PM
DOBMEIER ERIC Chief Operating Officer Dec 08, 2016 Option Exercise $20.52 12,500 256,500 97,467 Dec 12, 2016, 07:24 PM
DOBMEIER ERIC Chief Operating Officer Dec 08, 2016 Sale $65.92 12,500 824,042 87,767 Dec 12, 2016, 07:24 PM
HIMES VAUGHN B Chief Technical Officer Dec 07, 2016 Option Exercise $9.23 30,000 276,900 165,379 Dec 08, 2016, 08:05 PM
HIMES VAUGHN B Chief Technical Officer Dec 07, 2016 Sale $65.32 30,000 1,959,744 136,806 Dec 08, 2016, 08:05 PM
SIEGALL CLAY B President and CEO Dec 06, 2016 Option Exercise $10.26 14,465 148,481 649,258 Dec 08, 2016, 08:03 PM
SIEGALL CLAY B President and CEO Dec 06, 2016 Sale $66.17 14,465 957,145 638,835 Dec 08, 2016, 08:03 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Nov 09, 2016 Option Exercise $11.09 7,751 85,959 117,588 Nov 14, 2016, 05:55 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Nov 09, 2016 Sale $66.75 7,751 517,379 109,837 Nov 14, 2016, 05:55 PM
SIEGALL CLAY B President and CEO Nov 07, 2016 Option Exercise $10.26 14,465 148,481 645,948 Nov 09, 2016, 07:16 PM
SIEGALL CLAY B President and CEO Nov 07, 2016 Sale $58.43 14,465 845,144 638,835 Nov 09, 2016, 07:16 PM
LIPPMAN MARC E Director Nov 07, 2016 Sale $57.75 1,000 57,749 131,350 Nov 09, 2016, 07:13 PM
BAKER FELIX Director Nov 08, 2016 Buy $59.46 326,300 19,403,299 40,885,092 Nov 09, 2016, 04:37 PM
BAKER FELIX Director Nov 07, 2016 Buy $58.74 56,200 3,301,345 40,590,914 Nov 09, 2016, 04:37 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Nov 01, 2016 Sale $51.74 3,418 176,847 109,837 Nov 03, 2016, 08:04 PM
BAKER FELIX Director Nov 03, 2016 Buy $56.43 198,433 11,196,763 40,540,247 Nov 03, 2016, 06:12 PM
BAKER FELIX Director Nov 03, 2016 Buy $56.91 379,336 21,586,885 40,361,400 Nov 03, 2016, 06:11 PM
BAKER FELIX Director Nov 02, 2016 Buy $56.15 466,619 26,200,958 40,019,506 Nov 03, 2016, 06:11 PM
BAKER FELIX Director Nov 01, 2016 Buy $54.46 184,674 10,057,349 39,598,943 Nov 03, 2016, 06:11 PM
SIEGALL CLAY B President and CEO Oct 06, 2016 Option Exercise $10.27 14,465 148,553 650,058 Oct 11, 2016, 04:50 PM
SIEGALL CLAY B President and CEO Oct 06, 2016 Sale $54.41 14,465 787,022 638,835 Oct 11, 2016, 04:50 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Sep 22, 2016 Option Exercise $10.29 2,249 23,142 115,504 Sep 23, 2016, 07:12 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Sep 22, 2016 Sale $56.75 2,249 127,631 113,255 Sep 23, 2016, 07:12 PM
DOBMEIER ERIC Chief Operating Officer Sep 14, 2016 Option Exercise $12.00 22,918 275,016 110,385 Sep 15, 2016, 06:33 PM
DOBMEIER ERIC Chief Operating Officer Sep 14, 2016 Sale $54.04 22,918 1,238,469 87,767 Sep 15, 2016, 06:33 PM
Cline Darren S EVP, Commercial Sep 09, 2016 Option Exercise $15.46 4,167 64,422 55,743 Sep 13, 2016, 07:09 PM
BAKER FELIX Director Sep 13, 2016 Buy $51.09 141,202 7,213,981 39,432,496 Sep 13, 2016, 06:05 PM
BAKER FELIX Director Sep 12, 2016 Buy $51.14 49,889 2,551,111 39,305,533 Sep 13, 2016, 06:05 PM
BAKER FELIX Director Sep 09, 2016 Buy $50.42 256,220 12,917,842 39,260,675 Sep 13, 2016, 06:05 PM
SIEGALL CLAY B President and CEO Sep 08, 2016 Option Exercise $10.29 31,269 321,758 648,307 Sep 12, 2016, 09:52 PM
SIEGALL CLAY B President and CEO Sep 08, 2016 Sale $50.08 31,269 1,565,977 638,835 Sep 12, 2016, 09:52 PM
SIEGALL CLAY B President and CEO Sep 06, 2016 Option Exercise $8.38 23,957 200,776 622,449 Sep 08, 2016, 08:02 PM
SIEGALL CLAY B President and CEO Sep 06, 2016 Sale $45.40 11,653 529,007 617,038 Sep 08, 2016, 08:02 PM
GRYSKA DAVID W Director Sep 06, 2016 Option Exercise $10.20 10,000 102,000 37,650 Sep 08, 2016, 07:21 PM
Cline Darren S EVP, Commercial Sep 06, 2016 Sale $46.01 5,397 248,307 52,347 Sep 08, 2016, 07:18 PM
BAKER FELIX Director Sep 08, 2016 Buy $50.12 211,093 10,579,529 39,030,368 Sep 08, 2016, 05:39 PM
BAKER FELIX Director Sep 07, 2016 Buy $48.52 59,560 2,889,689 38,840,624 Sep 08, 2016, 05:39 PM
BAKER FELIX Director Sep 06, 2016 Buy $45.90 143,363 6,580,527 4,643,343 Sep 08, 2016, 05:39 PM
DOBMEIER ERIC Chief Operating Officer Aug 23, 2016 Option Exercise $26.10 3,831 99,989 71,356 Aug 24, 2016, 06:50 PM
DOBMEIER ERIC Chief Operating Officer Aug 23, 2016 Sale $48.00 12,589 604,272 58,767 Aug 24, 2016, 06:50 PM
Cline Darren S EVP, Commercial Aug 22, 2016 Sale $46.59 1,774 82,652 40,973 Aug 22, 2016, 09:38 PM
DOBMEIER ERIC Chief Operating Officer Aug 22, 2016 Sale $46.59 5,411 252,102 67,525 Aug 22, 2016, 09:36 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Aug 22, 2016 Sale $46.59 3,991 185,943 84,255 Aug 22, 2016, 09:34 PM
HIMES VAUGHN B EVP, Proc Svcs & Tech Ops Aug 22, 2016 Sale $46.59 3,991 185,943 108,779 Aug 22, 2016, 09:33 PM
SIEGALL CLAY B President and CEO Aug 22, 2016 Sale $46.59 23,381 1,089,337 532,734 Aug 22, 2016, 09:31 PM
SIMPSON TODD E Chief Financial Officer Aug 22, 2016 Sale $46.59 3,991 185,943 191,445 Aug 22, 2016, 09:29 PM
DOBMEIER ERIC Chief Operating Officer Aug 24, 2015 Option Exercise $20.27 4,933 99,985 79,340 Aug 22, 2016, 09:21 PM
DOBMEIER ERIC Chief Operating Officer Aug 20, 2015 Sale $42.02 8,548 359,226 74,407 Aug 22, 2016, 09:21 PM
Cline Darren S SVP, Commercial Aug 20, 2015 Sale $42.02 2,231 93,757 31,482 Aug 22, 2016, 09:19 PM
SIEGALL CLAY B President and CEO Aug 08, 2016 Option Exercise $6.44 11,660 75,128 563,733 Aug 10, 2016, 07:47 PM
SIEGALL CLAY B President and CEO Aug 08, 2016 Sale $47.19 11,660 550,212 556,115 Aug 10, 2016, 07:47 PM
SIEGALL CLAY B President and CEO Jul 27, 2016 Option Exercise $10.20 4,042 41,228 560,157 Jul 29, 2016, 07:40 PM
SIEGALL CLAY B President and CEO Jul 27, 2016 Sale $45.20 4,042 182,718 556,115 Jul 29, 2016, 07:40 PM
SIEGALL CLAY B President and CEO Jul 06, 2016 Option Exercise $4.45 7,618 33,900 561,287 Jul 07, 2016, 08:11 PM
SIEGALL CLAY B President and CEO Jul 06, 2016 Sale $40.56 7,618 308,999 556,115 Jul 07, 2016, 08:11 PM
SIEGALL CLAY B President and CEO Jun 06, 2016 Option Exercise $8.26 22,083 182,381 566,538 Jun 08, 2016, 07:32 PM
SIEGALL CLAY B President and CEO Jun 06, 2016 Sale $43.59 22,083 962,668 556,115 Jun 08, 2016, 07:32 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Jun 02, 2016 Option Exercise $10.29 5,000 51,450 88,246 Jun 06, 2016, 06:54 PM
Cline Darren S EVP, Commercial Jun 02, 2016 Sale $42.07 3,366 141,617 42,747 Jun 06, 2016, 06:52 PM
SIEGALL CLAY B President and CEO May 25, 2016 Option Exercise $10.27 36,738 377,335 585,085 May 27, 2016, 07:29 PM
SIEGALL CLAY B President and CEO May 27, 2016 Option Exercise $10.29 10,792 111,050 566,907 May 27, 2016, 07:29 PM
SIEGALL CLAY B President and CEO May 26, 2016 Option Exercise $10.29 1,130 11,628 557,245 May 27, 2016, 07:29 PM
SIEGALL CLAY B President and CEO May 27, 2016 Sale $40.10 10,792 432,810 556,115 May 27, 2016, 07:29 PM
SIEGALL CLAY B President and CEO May 26, 2016 Sale $40.07 1,130 45,284 556,115 May 27, 2016, 07:29 PM
SIEGALL CLAY B President and CEO May 25, 2016 Sale $40.51 36,738 1,488,275 556,115 May 27, 2016, 07:29 PM
SIEGALL CLAY B President and CEO May 24, 2016 Option Exercise $10.20 1,700 17,340 557,815 May 25, 2016, 07:04 PM
SIEGALL CLAY B President and CEO May 23, 2016 Option Exercise $10.20 6,700 68,340 562,815 May 25, 2016, 07:04 PM
SIEGALL CLAY B President and CEO May 24, 2016 Sale $40.00 1,700 68,000 556,115 May 25, 2016, 07:04 PM
SIEGALL CLAY B President and CEO May 23, 2016 Sale $40.12 6,700 268,777 556,115 May 25, 2016, 07:04 PM
BAKER FELIX Director May 20, 2016 Option Exercise $38.82 7,400 287,268 38,787,087 May 24, 2016, 05:50 PM
SIEGALL CLAY B President and CEO May 17, 2016 Option Exercise $4.45 7,618 33,900 563,733 May 19, 2016, 03:14 PM
SIEGALL CLAY B President and CEO May 17, 2016 Sale $35.16 7,618 267,849 556,115 May 19, 2016, 03:14 PM
SIEGALL CLAY B President and CEO Apr 25, 2016 Option Exercise $10.20 800 8,160 556,915 Apr 26, 2016, 08:17 PM
SIEGALL CLAY B President and CEO Apr 25, 2016 Sale $40.00 800 32,000 556,115 Apr 26, 2016, 08:17 PM
SIEGALL CLAY B President and CEO Apr 05, 2016 Option Exercise $4.45 7,618 33,900 563,733 Apr 07, 2016, 04:49 PM
SIEGALL CLAY B President and CEO Apr 05, 2016 Sale $36.12 7,618 275,162 556,115 Apr 07, 2016, 04:49 PM
SIEGALL CLAY B President and CEO Mar 22, 2016 Option Exercise $4.45 10,954 48,745 567,069 Mar 23, 2016, 07:44 PM
SIEGALL CLAY B President and CEO Mar 21, 2016 Option Exercise $4.45 4,282 19,055 560,397 Mar 23, 2016, 07:44 PM
SIEGALL CLAY B President and CEO Mar 21, 2016 Sale $35.01 4,282 149,913 556,115 Mar 23, 2016, 07:44 PM
SIEGALL CLAY B President and CEO Mar 22, 2016 Sale $35.72 10,954 391,317 557,015 Mar 23, 2016, 07:44 PM
BAKER FELIX Director Mar 17, 2016 Buy $31.85 124,065 3,951,304 38,783,387 Mar 21, 2016, 04:32 PM
BAKER FELIX Director Mar 16, 2016 Buy $31.77 569,203 18,084,599 38,671,506 Mar 16, 2016, 06:57 PM
BAKER FELIX Director Mar 15, 2016 Buy $32.08 661,093 21,210,834 38,158,204 Mar 16, 2016, 06:57 PM
BAKER FELIX Director Mar 14, 2016 Buy $33.77 118,941 4,016,519 37,562,036 Mar 16, 2016, 06:57 PM
BAKER FELIX Director Mar 11, 2016 Buy $33.10 195,765 6,480,738 37,454,776 Mar 11, 2016, 06:13 PM
BAKER FELIX Director Mar 10, 2016 Buy $32.34 290,231 9,386,567 37,278,782 Mar 11, 2016, 06:13 PM
BAKER FELIX Director Mar 09, 2016 Buy $32.03 208,670 6,683,985 37,017,863 Mar 11, 2016, 06:13 PM
WELCH DANIEL G Director Mar 08, 2016 Option Exercise $9.82 25,000 245,500 41,819 Mar 10, 2016, 03:16 PM
BAKER FELIX Director Mar 08, 2016 Option Exercise $4.18 20,000 83,600 36,692,540 Mar 08, 2016, 05:04 PM
BAKER FELIX Director Mar 04, 2016 Buy $32.36 288,058 9,322,814 36,627,462 Mar 08, 2016, 05:04 PM
BAKER FELIX Director Mar 07, 2016 Buy $33.69 61,265 2,063,918 36,682,540 Mar 08, 2016, 05:04 PM
BAKER FELIX Director Mar 02, 2016 Buy $32.67 400,000 13,068,812 36,367,808 Mar 02, 2016, 06:31 PM
BAKER FELIX Director Mar 01, 2016 Buy $31.24 24,200 756,112 36,007,250 Mar 02, 2016, 06:31 PM
BAKER FELIX Director Feb 29, 2016 Buy $30.39 251,722 7,650,310 35,985,436 Mar 02, 2016, 06:31 PM
BAKER FELIX Director Feb 26, 2016 Buy $30.13 44,300 1,334,945 35,758,535 Feb 26, 2016, 05:42 PM
BAKER FELIX Director Feb 25, 2016 Buy $29.86 142,702 4,261,553 35,718,720 Feb 26, 2016, 05:42 PM
BAKER FELIX Director Feb 24, 2016 Buy $28.99 127,506 3,696,568 35,590,465 Feb 26, 2016, 05:42 PM
BAKER FELIX Director Feb 22, 2016 Buy $30.21 243,411 7,354,639 35,475,868 Feb 22, 2016, 05:34 PM
BAKER FELIX Director Feb 19, 2016 Buy $29.20 506,526 14,790,560 35,257,100 Feb 22, 2016, 05:34 PM
BAKER FELIX Director Feb 18, 2016 Buy $29.94 251,534 7,530,350 34,800,251 Feb 22, 2016, 05:34 PM
Orwin John A Director Feb 12, 2016 Buy $28.33 2,000 56,660 10,700 Feb 17, 2016, 07:50 PM
BAKER FELIX Director Feb 17, 2016 Buy $31.25 805,267 25,161,937 34,573,386 Feb 17, 2016, 06:05 PM
BAKER FELIX Director Feb 16, 2016 Buy $29.80 270,163 8,049,663 33,847,095 Feb 17, 2016, 06:05 PM
BAKER FELIX Director Feb 12, 2016 Buy $27.93 193,717 5,410,745 33,588,605 Feb 17, 2016, 06:05 PM
HIMES VAUGHN B EVP, Proc Svcs & Tech Ops Dec 18, 2015 Option Exercise $9.47 35,036 331,692 111,248 Dec 21, 2015, 05:01 PM
HIMES VAUGHN B EVP, Proc Svcs & Tech Ops Dec 15, 2015 Option Exercise $9.23 40,500 373,815 116,712 Dec 16, 2015, 08:29 PM
HIMES VAUGHN B EVP, Proc Svcs & Tech Ops Dec 15, 2015 Sale $39.94 40,500 1,617,493 76,212 Dec 16, 2015, 08:29 PM
SIEGALL CLAY B President and CEO Dec 03, 2015 Option Exercise $5.63 3,720 20,944 559,835 Dec 04, 2015, 06:01 PM
SIEGALL CLAY B President and CEO Dec 03, 2015 Sale $39.99 3,720 148,763 556,115 Dec 04, 2015, 06:01 PM
BAKER FELIX Director Nov 18, 2015 Buy $43.61 14,638 638,321 33,114,132 Nov 20, 2015, 05:02 PM
BAKER FELIX Director Nov 20, 2015 Buy $43.98 181,647 7,988,259 33,428,852 Nov 20, 2015, 05:02 PM
BAKER FELIX Director Nov 19, 2015 Buy $43.93 133,073 5,845,378 33,247,205 Nov 20, 2015, 05:02 PM
SIEGALL CLAY B President and CEO Nov 17, 2015 Sale $45.40 87,473 3,970,951 556,115 Nov 19, 2015, 05:18 PM
Cline Darren S SVP, Commercial Nov 11, 2015 Sale $45.68 5,769 263,548 37,713 Nov 13, 2015, 05:49 PM
BAKER FELIX Director Nov 06, 2015 Buy $41.94 417,924 17,529,497 32,582,794 Nov 10, 2015, 07:57 PM
BAKER FELIX Director Nov 10, 2015 Buy $44.00 9,400 413,600 33,099,494 Nov 10, 2015, 07:57 PM
BAKER FELIX Director Nov 09, 2015 Buy $43.76 507,300 22,200,588 33,090,094 Nov 10, 2015, 07:57 PM
DOBMEIER ERIC Chief Operating Officer Nov 06, 2015 Sale $42.50 17,452 741,710 80,888 Nov 06, 2015, 07:35 PM
SIEGALL CLAY B President and CEO Nov 04, 2015 Option Exercise $5.63 3,718 20,932 647,306 Nov 05, 2015, 05:46 PM
SIEGALL CLAY B President and CEO Nov 04, 2015 Sale $43.14 3,718 160,395 643,588 Nov 05, 2015, 05:46 PM
GRYSKA DAVID W Director Nov 05, 2015 Sale $43.57 10,000 435,737 23,950 Nov 05, 2015, 05:17 PM
SIEGALL CLAY B President and CEO Oct 28, 2015 Option Exercise $5.12 32,265 165,058 643,588 Oct 29, 2015, 08:30 PM
SIEGALL CLAY B President and CEO Oct 05, 2015 Option Exercise $5.63 3,718 20,932 615,041 Oct 07, 2015, 04:47 PM
SIEGALL CLAY B President and CEO Oct 05, 2015 Sale $41.30 3,718 153,541 611,323 Oct 07, 2015, 04:47 PM
SIMPSON TODD E Chief Financial Officer Sep 29, 2015 Option Exercise $13.51 14,801 199,991 194,675 Oct 01, 2015, 03:10 PM
BAKER FELIX Director Sep 15, 2015 Buy $48.28 626,259 30,237,807 32,164,870 Sep 15, 2015, 07:04 PM
BAKER FELIX Director Sep 14, 2015 Buy $46.34 320,438 14,849,199 31,538,611 Sep 15, 2015, 07:04 PM
BAKER FELIX Director Sep 11, 2015 Buy $41.43 4,212,787 174,517,109 31,218,173 Sep 15, 2015, 07:04 PM
SIEGALL CLAY B President and CEO Sep 03, 2015 Option Exercise $5.63 3,718 20,932 615,041 Sep 04, 2015, 06:29 PM
SIEGALL CLAY B President and CEO Sep 03, 2015 Sale $40.12 3,718 149,166 611,323 Sep 04, 2015, 06:29 PM
SIEGALL CLAY B President and CEO Aug 20, 2015 Sale $42.02 31,754 1,334,440 525,268 Aug 25, 2015, 09:28 PM
DOBMEIER ERIC Chief Operating Officer Aug 24, 2015 Option Exercise $20.27 4,933 99,985 79,340 Aug 25, 2015, 08:59 PM
DOBMEIER ERIC Chief Operating Officer Aug 20, 2015 Sale $42.02 8,548 359,226 74,407 Aug 25, 2015, 08:59 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Aug 20, 2015 Sale $42.02 4,462 187,513 62,724 Aug 25, 2015, 08:48 PM
Cline Darren S SVP, Commercial Aug 20, 2015 Sale $42.02 2,231 93,757 31,482 Aug 25, 2015, 08:46 PM
SIMPSON TODD E Chief Financial Officer Aug 20, 2015 Sale $42.02 5,825 244,794 162,874 Aug 25, 2015, 08:32 PM
HIMES VAUGHN B EVP, Proc Svcs & Tech Ops Aug 20, 2015 Sale $42.02 5,997 252,021 61,212 Aug 25, 2015, 08:30 PM
SIEGALL CLAY B President and CEO Aug 05, 2015 Option Exercise $5.63 3,718 20,932 560,740 Aug 07, 2015, 05:46 PM
SIEGALL CLAY B President and CEO Aug 05, 2015 Sale $46.91 3,718 174,411 557,022 Aug 07, 2015, 05:46 PM
SIEGALL CLAY B President and CEO Jul 06, 2015 Option Exercise $5.63 3,718 20,932 560,740 Jul 08, 2015, 06:07 PM
SIEGALL CLAY B President and CEO Jul 06, 2015 Sale $46.94 3,718 174,515 557,022 Jul 08, 2015, 06:07 PM
SIEGALL CLAY B President and CEO Jun 03, 2015 Option Exercise $5.63 3,718 20,932 560,740 Jun 04, 2015, 06:10 PM
SIEGALL CLAY B President and CEO Jun 03, 2015 Sale $45.72 3,718 169,971 557,022 Jun 04, 2015, 06:10 PM
BAKER FELIX Director May 21, 2015 Buy $43.38 362,459 15,723,084 27,005,386 May 21, 2015, 07:42 PM
BAKER FELIX Director May 20, 2015 Buy $42.56 374,298 15,929,272 26,652,609 May 21, 2015, 07:42 PM
BAKER FELIX Director May 19, 2015 Buy $40.87 214,129 8,751,249 26,268,629 May 21, 2015, 07:42 PM
BAKER FELIX Director May 15, 2015 Option Exercise $39.94 7,400 295,556 26,054,500 May 18, 2015, 06:45 PM
SIEGALL CLAY B President and CEO May 08, 2015 Option Exercise $5.63 52,052 293,053 609,074 May 12, 2015, 07:31 PM
SIEGALL CLAY B President and CEO May 08, 2015 Sale $40.65 52,052 2,116,080 557,022 May 12, 2015, 07:31 PM
BAKER FELIX Director May 11, 2015 Option Exercise $5.11 20,000 102,200 26,050,800 May 12, 2015, 09:04 AM
DOBMEIER ERIC Chief Operating Officer May 08, 2015 Sale $40.38 17,074 689,380 82,777 May 08, 2015, 06:50 PM
BAKER FELIX Director May 07, 2015 Buy $37.15 47,717 1,772,790 26,040,800 May 07, 2015, 09:32 PM
BAKER FELIX Director May 06, 2015 Buy $36.41 453,995 16,530,995 25,993,083 May 07, 2015, 09:32 PM
BAKER FELIX Director May 05, 2015 Buy $34.69 530,952 18,419,925 25,539,088 May 07, 2015, 09:32 PM
GRYSKA DAVID W Director Apr 08, 2015 Option Exercise $8.38 5,000 41,900 30,250 Apr 10, 2015, 06:43 PM
Cline Darren S SVP, Commercial Mar 13, 2015 Sale $38.65 7,500 289,876 33,135 Mar 17, 2015, 07:10 PM
HIMES VAUGHN B EVP, Proc Svcs & Tech Ops Mar 12, 2015 Option Exercise $9.23 20,000 184,600 87,209 Mar 16, 2015, 07:23 PM
HIMES VAUGHN B EVP, Proc Svcs & Tech Ops Mar 12, 2015 Sale $36.65 20,000 732,992 67,209 Mar 16, 2015, 07:23 PM
BAKER FELIX Director Mar 10, 2015 Buy $34.54 9,319 321,921 25,008,136 Mar 11, 2015, 06:55 PM
BAKER FELIX Director Mar 09, 2015 Buy $34.66 275,717 9,556,609 24,998,817 Mar 11, 2015, 06:55 PM
BAKER FELIX Director Mar 04, 2015 Buy $34.82 23,621 822,418 24,723,100 Mar 05, 2015, 06:02 PM
BAKER FELIX Director Mar 03, 2015 Buy $34.84 425,220 14,814,701 24,699,479 Mar 05, 2015, 06:02 PM
BAKER FELIX Director Feb 25, 2015 Buy $34.48 63,650 2,194,758 24,274,259 Feb 26, 2015, 07:12 PM
BAKER FELIX Director Feb 24, 2015 Buy $33.76 217,465 7,341,491 24,210,609 Feb 26, 2015, 07:12 PM
SIEGALL CLAY B President and CEO Jan 06, 2015 Option Exercise $5.92 16,804 99,480 576,514 Jan 08, 2015, 05:47 PM
SIEGALL CLAY B President and CEO Jan 06, 2015 Sale $31.80 16,804 534,320 559,710 Jan 08, 2015, 05:47 PM
BAKER FELIX Director Dec 16, 2014 Buy $31.94 1,909,979 60,997,871 23,993,144 Dec 17, 2014, 05:00 PM
BAKER FELIX Director Dec 15, 2014 Buy $31.70 973,399 30,861,289 22,083,165 Dec 17, 2014, 05:00 PM
BAKER FELIX Director Dec 10, 2014 Buy $34.40 654,150 22,501,700 21,109,766 Dec 10, 2014, 08:04 PM
BAKER FELIX Director Dec 09, 2014 Buy $34.16 128,430 4,387,345 20,455,616 Dec 10, 2014, 08:04 PM
BAKER FELIX Director Dec 08, 2014 Buy $32.93 465,316 15,320,685 20,327,186 Dec 10, 2014, 08:04 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. Nov 12, 2014 Option Exercise $9.23 10,000 92,300 77,209 Nov 14, 2014, 05:13 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. Nov 12, 2014 Sale $37.52 10,000 375,169 67,209 Nov 14, 2014, 05:13 PM
BAKER FELIX Director Nov 06, 2014 Buy $33.98 1,200,972 40,805,170 19,408,917 Nov 10, 2014, 06:52 PM
BAKER FELIX Director Nov 10, 2014 Buy $36.43 241,249 8,787,529 19,861,870 Nov 10, 2014, 06:52 PM
BAKER FELIX Director Nov 07, 2014 Buy $35.72 211,704 7,561,461 19,620,621 Nov 10, 2014, 06:52 PM
SIEGALL CLAY B President and CEO Sep 04, 2014 Option Exercise $5.92 5,600 33,152 565,310 Sep 05, 2014, 07:19 PM
SIEGALL CLAY B President and CEO Sep 04, 2014 Sale $42.54 5,600 238,224 559,710 Sep 05, 2014, 07:19 PM
DOBMEIER ERIC Chief Operating Officer Aug 27, 2014 Option Exercise $12.00 8,333 99,996 99,765 Aug 28, 2014, 04:27 PM
SIMPSON TODD E Chief Financial Officer Aug 24, 2014 Sale $43.55 3,696 160,957 151,699 Aug 27, 2014, 04:25 PM
SIEGALL CLAY B President and CEO Aug 24, 2014 Sale $43.55 25,507 1,110,804 499,710 Aug 27, 2014, 04:25 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. Aug 24, 2014 Sale $43.55 3,310 144,147 52,209 Aug 27, 2014, 04:24 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Aug 24, 2014 Sale $43.55 2,772 120,718 46,481 Aug 27, 2014, 04:24 PM
DOBMEIER ERIC Chief Operating Officer Aug 25, 2014 Sale $43.55 4,818 209,819 73,432 Aug 27, 2014, 04:23 PM
BOERNER CHRISTOPHER S. Executive Vice President, Comm Aug 24, 2014 Sale $43.55 1,248 54,349 56,358 Aug 27, 2014, 04:22 PM
SIEGALL CLAY B President and CEO Aug 12, 2014 Option Exercise $5.92 8,500 50,320 533,717 Aug 13, 2014, 07:28 PM
SIEGALL CLAY B President and CEO Aug 11, 2014 Option Exercise $5.92 2,700 15,984 527,917 Aug 13, 2014, 07:28 PM
SIEGALL CLAY B President and CEO Aug 12, 2014 Sale $40.48 8,500 344,090 525,217 Aug 13, 2014, 07:28 PM
SIEGALL CLAY B President and CEO Aug 11, 2014 Sale $40.05 2,700 108,130 525,217 Aug 13, 2014, 07:28 PM
BAKER FELIX Director Jun 13, 2014 Buy $39.89 88,587 3,533,526 18,207,945 Jun 16, 2014, 04:33 PM
BAKER FELIX Director Jun 12, 2014 Buy $39.94 128,008 5,112,199 18,121,499 Jun 16, 2014, 04:33 PM
SIEGALL CLAY B President and CEO Jun 10, 2014 Option Exercise $5.92 11,200 66,304 536,417 Jun 12, 2014, 08:33 PM
SIEGALL CLAY B President and CEO Jun 10, 2014 Sale $40.14 11,200 449,574 525,217 Jun 12, 2014, 08:33 PM
BAKER FELIX Director Jun 09, 2014 Buy $38.92 251,093 9,772,651 17,996,584 Jun 09, 2014, 05:26 PM
BAKER FELIX Director Jun 06, 2014 Buy $37.41 174,987 6,546,471 17,751,559 Jun 09, 2014, 05:26 PM
BAKER FELIX Director Jun 05, 2014 Buy $37.67 120,172 4,526,317 17,580,806 Jun 09, 2014, 05:26 PM
BAKER FELIX Director Jun 04, 2014 Buy $36.13 87,042 3,145,161 17,463,541 Jun 04, 2014, 07:27 PM
BAKER FELIX Director Jun 03, 2014 Buy $34.47 100,304 3,457,722 17,378,605 Jun 04, 2014, 07:27 PM
BAKER FELIX Director Jun 02, 2014 Buy $34.09 94,617 3,225,210 17,280,727 Jun 04, 2014, 07:27 PM
BAKER FELIX Director May 14, 2014 Option Exercise $7.26 30,000 217,800 16,999,872 May 16, 2014, 07:00 PM
BAKER FELIX Director May 16, 2014 Buy $34.05 168,411 5,734,196 17,188,399 May 16, 2014, 07:00 PM
BAKER FELIX Director May 15, 2014 Buy $34.26 21,200 726,356 17,020,560 May 16, 2014, 07:00 PM
BAKER FELIX Director May 09, 2014 Buy $34.16 138,073 4,715,922 16,989,872 May 16, 2014, 04:52 PM
BAKER FELIX Director May 08, 2014 Buy $34.02 233,055 7,929,305 16,855,137 May 16, 2014, 04:52 PM
BAKER FELIX Director May 07, 2014 Buy $33.59 117,254 3,938,140 16,627,717 May 16, 2014, 04:52 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. May 09, 2014 Option Exercise $9.23 10,000 92,300 65,519 May 13, 2014, 08:42 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. May 09, 2014 Sale $35.00 10,000 350,000 55,519 May 13, 2014, 08:42 PM
BAKER FELIX Director May 09, 2013 Buy $34.16 138,073 4,715,922 16,989,872 May 09, 2014, 05:16 PM
BAKER FELIX Director May 08, 2013 Buy $34.02 233,055 7,929,305 16,855,137 May 09, 2014, 05:16 PM
BAKER FELIX Director May 07, 2013 Buy $33.59 117,254 3,938,140 16,627,717 May 09, 2014, 05:16 PM
SIEGALL CLAY B President and CEO Apr 03, 2014 Option Exercise $5.92 5,600 33,152 961,296 Apr 07, 2014, 06:32 PM
SIEGALL CLAY B President and CEO Apr 03, 2014 Sale $43.34 5,600 242,702 955,696 Apr 07, 2014, 06:32 PM
SIEGALL CLAY B President and CEO Mar 05, 2014 Option Exercise $5.80 9,318 54,084 961,296 Mar 07, 2014, 08:05 PM
SIEGALL CLAY B President and CEO Mar 05, 2014 Sale $52.89 9,318 492,796 955,696 Mar 07, 2014, 08:05 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. Feb 28, 2014 Option Exercise $9.23 11,300 104,299 55,519 Mar 04, 2014, 06:47 PM
BERGER FRANKLIN M Director Feb 21, 2014 Option Exercise $12.76 7,500 95,700 204,720 Feb 25, 2014, 06:04 PM
BOERNER CHRISTOPHER S. SVP, Commercial Feb 21, 2014 Sale $54.98 1,452 79,825 46,075 Feb 25, 2014, 03:35 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Feb 20, 2014 Sale $53.25 1,241 66,083 48,670 Feb 24, 2014, 07:25 PM
HIMES VAUGHN B EVP, Tech, Ops. & Proc. Sci. Feb 19, 2014 Option Exercise $9.23 3,000 27,690 49,307 Feb 21, 2014, 06:39 PM
HIMES VAUGHN B EVP, Tech, Ops. & Proc. Sci. Feb 19, 2014 Sale $52.01 5,088 264,627 46,307 Feb 21, 2014, 06:39 PM
SIEGALL CLAY B President and CEO Feb 13, 2014 Option Exercise $10.33 12,142 125,427 1,055,696 Feb 18, 2014, 07:45 PM
SIEGALL CLAY B President and CEO Feb 18, 2014 Sale $51.97 100,000 5,197,010 955,696 Feb 18, 2014, 07:45 PM
DOBMEIER ERIC Chief Operating Officer Jan 21, 2014 Sale $47.92 56,010 2,683,958 112,408 Jan 23, 2014, 08:52 PM
DRACHMAN JONATHAN G CMO & EVP, R & D Jan 16, 2014 Sale $45.75 1,201 54,946 49,911 Jan 21, 2014, 07:44 PM
SIEGALL CLAY B President and CEO Jan 02, 2014 Option Exercise $10.33 1,858 19,193 1,045,412 Jan 06, 2014, 06:46 PM
SIEGALL CLAY B President and CEO Jan 02, 2014 Sale $39.27 1,858 72,957 1,043,554 Jan 06, 2014, 06:46 PM
BAKER FELIX Director Dec 13, 2013 Buy $39.65 43,709 1,733,276 16,436,458 Dec 16, 2013, 07:42 PM
BAKER FELIX Director Dec 12, 2013 Buy $39.59 284,610 11,268,201 16,393,812 Dec 16, 2013, 07:42 PM
BAKER FELIX Director Dec 16, 2013 Buy $39.92 78,759 3,143,952 16,513,298 Dec 16, 2013, 07:42 PM
SIEGALL CLAY B President and CEO Dec 05, 2013 Option Exercise $5.92 18,996 112,456 1,043,554 Dec 09, 2013, 06:38 PM
BAKER FELIX Director Dec 05, 2013 Buy $44.00 365,676 16,089,489 16,116,121 Dec 05, 2013, 08:13 PM
BAKER FELIX Director Dec 04, 2013 Buy $43.11 270,795 11,675,184 15,759,353 Dec 05, 2013, 08:13 PM
BAKER FELIX Director Dec 03, 2013 Buy $42.44 369,430 15,678,059 15,495,154 Dec 05, 2013, 08:13 PM
SIEGALL CLAY B President and CEO Dec 02, 2013 Option Exercise $10.33 2,000 20,660 1,026,558 Dec 04, 2013, 05:42 PM
SIEGALL CLAY B President and CEO Dec 02, 2013 Sale $41.25 2,000 82,492 1,024,558 Dec 04, 2013, 05:42 PM
SIEGALL CLAY B President and CEO Nov 01, 2013 Option Exercise $10.33 2,000 20,660 1,026,558 Nov 05, 2013, 06:25 PM
SIEGALL CLAY B President and CEO Nov 01, 2013 Sale $38.63 2,000 77,254 1,024,558 Nov 05, 2013, 06:25 PM
SIEGALL CLAY B President and CEO Oct 01, 2013 Option Exercise $10.33 2,000 20,660 1,026,558 Oct 03, 2013, 07:36 PM
SIEGALL CLAY B President and CEO Oct 01, 2013 Sale $43.87 2,000 87,732 1,024,558 Oct 03, 2013, 07:36 PM
DOBMEIER ERIC Chief Operating Officer Sep 10, 2013 Option Exercise $22.24 40,000 889,599 156,155 Sep 11, 2013, 07:00 PM
DOBMEIER ERIC Chief Operating Officer Sep 10, 2013 Sale $46.40 42,000 1,948,960 135,843 Sep 11, 2013, 07:00 PM
DOBMEIER ERIC Chief Operating Officer Sep 05, 2013 Option Exercise $15.46 15,000 231,900 150,843 Sep 05, 2013, 07:17 PM
DOBMEIER ERIC Chief Operating Officer Sep 03, 2013 Option Exercise $13.28 68,223 905,685 165,036 Sep 05, 2013, 07:17 PM
DOBMEIER ERIC Chief Operating Officer Sep 05, 2013 Sale $44.00 15,000 660,000 135,843 Sep 05, 2013, 07:17 PM
DOBMEIER ERIC Chief Operating Officer Sep 03, 2013 Sale $42.29 60,000 2,537,664 135,843 Sep 05, 2013, 07:17 PM
SIEGALL CLAY B President and CEO Sep 03, 2013 Option Exercise $10.33 2,000 20,660 1,079,211 Sep 05, 2013, 05:55 PM
SIEGALL CLAY B President and CEO Sep 03, 2013 Sale $43.90 102,000 4,477,802 1,077,211 Sep 05, 2013, 05:55 PM
GRYSKA DAVID W Director Sep 03, 2013 Option Exercise $10.08 10,000 100,800 32,000 Sep 05, 2013, 05:53 PM
GRYSKA DAVID W Director Sep 03, 2013 Sale $42.48 10,000 424,800 22,000 Sep 05, 2013, 05:53 PM
SIMPSON TODD E Chief Financial Officer Aug 28, 2013 Option Exercise $11.03 30,366 335,057 155,395 Aug 30, 2013, 04:30 PM
SIMPSON TODD E Chief Financial Officer Aug 27, 2013 Option Exercise $21.73 37,763 820,546 137,529 Aug 30, 2013, 04:30 PM
SIMPSON TODD E Chief Financial Officer Aug 27, 2013 Sale $41.45 37,763 1,565,186 125,029 Aug 30, 2013, 04:30 PM
BERGER FRANKLIN M Director Aug 28, 2013 Option Exercise $12.76 10,000 127,600 197,220 Aug 30, 2013, 04:30 PM
SIEGALL CLAY B President and CEO Aug 19, 2013 Sale $40.91 7,653 313,084 1,069,558 Aug 21, 2013, 09:37 PM
SIMPSON TODD E Chief Financial Officer Aug 19, 2013 Sale $40.91 3,328 136,148 110,629 Aug 21, 2013, 09:29 PM
DOBMEIER ERIC Chief Operating Officer Aug 19, 2013 Sale $40.91 3,328 136,148 109,620 Aug 21, 2013, 09:26 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. Aug 19, 2013 Sale $40.91 1,736 71,020 31,907 Aug 21, 2013, 09:21 PM
BOERNER CHRISTOPHER S. SVP, Commercial Aug 19, 2013 Sale $40.91 226 9,246 33,527 Aug 21, 2013, 09:18 PM
SIEGALL CLAY B President and CEO Aug 01, 2013 Option Exercise $10.33 2,000 20,660 1,079,211 Aug 02, 2013, 05:49 PM
SIEGALL CLAY B President and CEO Aug 01, 2013 Sale $40.03 2,000 80,063 1,077,211 Aug 02, 2013, 05:49 PM
SIMPSON TODD E Chief Financial Officer Jul 12, 2013 Option Exercise $14.12 47,527 671,238 143,123 Jul 15, 2013, 07:58 PM
SIMPSON TODD E Chief Financial Officer Jul 11, 2013 Option Exercise $12.01 45,000 540,238 157,471 Jul 15, 2013, 07:58 PM
SIMPSON TODD E Chief Financial Officer Jul 12, 2013 Sale $37.94 47,527 1,803,174 113,957 Jul 15, 2013, 07:58 PM
SIMPSON TODD E Chief Financial Officer Jul 11, 2013 Sale $36.94 45,000 1,662,300 113,957 Jul 15, 2013, 07:58 PM
SIEGALL CLAY B President and CEO Jul 01, 2013 Option Exercise $10.33 2,000 20,660 1,079,211 Jul 02, 2013, 04:47 PM
SIEGALL CLAY B President and CEO Jul 01, 2013 Sale $32.59 2,000 65,186 1,077,211 Jul 02, 2013, 04:47 PM
AKKARAJU SRINIVAS Director Jun 14, 2013 Option Exercise $8.38 5,000 41,900 18,905 Jun 17, 2013, 07:28 PM
AKKARAJU SRINIVAS Director Jun 14, 2013 Sale $32.75 5,000 163,750 13,905 Jun 17, 2013, 07:28 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. Jun 13, 2013 Option Exercise $9.23 10,000 92,300 43,643 Jun 17, 2013, 07:26 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. Jun 13, 2013 Sale $32.11 10,000 321,100 33,643 Jun 17, 2013, 07:26 PM
SIEGALL CLAY B President and CEO Jun 03, 2013 Option Exercise $10.33 2,000 20,660 1,079,211 Jun 05, 2013, 04:48 PM
SIEGALL CLAY B President and CEO Jun 03, 2013 Sale $33.88 2,000 67,762 1,077,211 Jun 05, 2013, 04:48 PM
AKKARAJU SRINIVAS Director May 10, 2013 Option Exercise $12.76 17,500 223,300 27,905 May 14, 2013, 09:30 AM
AKKARAJU SRINIVAS Director May 10, 2013 Sale $37.17 17,500 650,430 10,405 May 14, 2013, 09:30 AM
SIEGALL CLAY B President and CEO May 01, 2013 Option Exercise $10.33 2,000 20,660 1,079,211 May 03, 2013, 06:39 PM
SIEGALL CLAY B President and CEO May 01, 2013 Sale $36.58 2,000 73,153 1,077,211 May 03, 2013, 06:39 PM
SIEGALL CLAY B President and CEO Apr 01, 2013 Option Exercise $10.33 2,000 20,660 1,079,211 Apr 03, 2013, 06:31 PM
SIEGALL CLAY B President and CEO Apr 01, 2013 Sale $35.53 2,000 71,062 1,077,211 Apr 03, 2013, 06:31 PM
BOERNER CHRISTOPHER S. SVP, Commercial Mar 15, 2013 Option Exercise $15.10 8,500 128,350 42,253 Mar 19, 2013, 07:23 PM
BOERNER CHRISTOPHER S. SVP, Commercial Mar 15, 2013 Sale $33.61 8,500 285,663 33,753 Mar 19, 2013, 07:23 PM
DOBMEIER ERIC Chief Operating Officer Mar 11, 2013 Option Exercise $12.11 50,000 605,671 158,392 Mar 12, 2013, 07:10 PM
DOBMEIER ERIC Chief Operating Officer Mar 11, 2013 Sale $31.16 60,000 1,869,471 122,948 Mar 12, 2013, 07:10 PM
SIMPSON TODD E Chief Financial Officer Mar 07, 2013 Option Exercise $12.12 20,176 244,610 133,451 Mar 08, 2013, 07:13 PM
SIMPSON TODD E Chief Financial Officer Mar 07, 2013 Sale $30.75 49,718 1,528,706 113,957 Mar 08, 2013, 07:13 PM
DOBMEIER ERIC Chief Operating Officer Mar 05, 2013 Option Exercise $12.16 12,567 152,815 135,515 Mar 06, 2013, 07:16 PM
DOBMEIER ERIC Chief Operating Officer Mar 04, 2013 Option Exercise $12.16 37,433 455,185 160,381 Mar 06, 2013, 07:16 PM
DOBMEIER ERIC Chief Operating Officer Mar 06, 2013 Option Exercise $12.00 50,000 600,000 172,948 Mar 06, 2013, 07:16 PM
DOBMEIER ERIC Chief Operating Officer Mar 04, 2013 Sale $28.95 37,433 1,083,685 122,948 Mar 06, 2013, 07:16 PM
DOBMEIER ERIC Chief Operating Officer Mar 06, 2013 Sale $30.42 50,000 1,520,955 122,948 Mar 06, 2013, 07:16 PM
DOBMEIER ERIC Chief Operating Officer Mar 05, 2013 Sale $28.95 12,567 363,815 122,948 Mar 06, 2013, 07:16 PM
SIEGALL CLAY B President and CEO Mar 01, 2013 Option Exercise $10.33 2,000 20,660 1,172,961 Mar 05, 2013, 07:07 PM
SIEGALL CLAY B President and CEO Mar 05, 2013 Sale $28.87 68,750 1,984,950 1,077,211 Mar 05, 2013, 07:07 PM
SIEGALL CLAY B President and CEO Mar 01, 2013 Sale $28.30 27,000 764,067 1,170,961 Mar 05, 2013, 07:07 PM
GRYSKA DAVID W Director Feb 26, 2013 Option Exercise $6.69 10,000 66,900 18,500 Feb 27, 2013, 04:40 PM
GRYSKA DAVID W Director Feb 25, 2013 Sale $27.17 10,000 271,700 8,500 Feb 27, 2013, 04:40 PM
SIEGALL CLAY B President and CEO Feb 01, 2013 Option Exercise $10.33 2,000 20,660 1,172,961 Feb 05, 2013, 07:32 PM
SIEGALL CLAY B President and CEO Feb 01, 2013 Sale $29.61 2,000 59,216 1,170,961 Feb 05, 2013, 07:32 PM
Reynolds Thomas C Chief Medical Officer Jan 25, 2013 Option Exercise $15.46 2,083 32,203 59,684 Jan 29, 2013, 08:16 PM
Reynolds Thomas C Chief Medical Officer Jan 28, 2013 Option Exercise $12.08 5,207 62,900 60,205 Jan 29, 2013, 08:16 PM
Reynolds Thomas C Chief Medical Officer Jan 25, 2013 Sale $29.84 2,083 62,155 57,601 Jan 29, 2013, 08:16 PM
Reynolds Thomas C Chief Medical Officer Jan 28, 2013 Sale $30.19 5,207 157,188 57,601 Jan 29, 2013, 08:16 PM
Reynolds Thomas C Chief Medical Officer Jan 15, 2013 Option Exercise $11.62 125,079 1,452,804 93,094 Jan 17, 2013, 08:12 PM
Reynolds Thomas C Chief Medical Officer Jan 15, 2013 Sale $28.00 125,079 3,502,526 57,601 Jan 17, 2013, 08:12 PM
DOBMEIER ERIC Chief Operating Officer Jan 04, 2013 Option Exercise $11.09 60,000 665,400 173,829 Jan 04, 2013, 06:49 PM
DOBMEIER ERIC Chief Operating Officer Jan 04, 2013 Sale $24.95 50,983 1,272,026 122,846 Jan 04, 2013, 06:49 PM
SIEGALL CLAY B President and CEO Jan 04, 2013 Option Exercise $10.33 2,000 20,660 1,172,961 Jan 04, 2013, 06:46 PM
SIEGALL CLAY B President and CEO Jan 02, 2013 Option Exercise $3.30 6,249 20,622 1,177,210 Jan 04, 2013, 06:46 PM
SIEGALL CLAY B President and CEO Jan 02, 2013 Sale $23.83 6,249 148,939 1,170,961 Jan 04, 2013, 06:46 PM
SIEGALL CLAY B President and CEO Jan 04, 2013 Sale $25.05 2,000 50,104 1,170,961 Jan 04, 2013, 06:46 PM
DOBMEIER ERIC Chief Operating Officer Dec 17, 2012 Option Exercise $10.92 62,418 681,573 163,829 Dec 19, 2012, 04:50 PM
DOBMEIER ERIC Chief Operating Officer Dec 17, 2012 Sale $23.70 50,000 1,184,955 113,829 Dec 19, 2012, 04:50 PM
Reynolds Thomas C Chief Medical Officer Dec 10, 2012 Option Exercise $10.94 6,588 72,061 62,939 Dec 10, 2012, 06:17 PM
Reynolds Thomas C Chief Medical Officer Dec 07, 2012 Option Exercise $10.29 30,000 308,700 87,601 Dec 10, 2012, 06:17 PM
Reynolds Thomas C Chief Medical Officer Dec 06, 2012 Option Exercise $12.16 30,000 364,800 87,601 Dec 10, 2012, 06:17 PM
Reynolds Thomas C Chief Medical Officer Dec 07, 2012 Sale $25.77 30,000 773,082 57,601 Dec 10, 2012, 06:17 PM
Reynolds Thomas C Chief Medical Officer Dec 06, 2012 Sale $25.77 30,000 772,983 57,601 Dec 10, 2012, 06:17 PM
Reynolds Thomas C Chief Medical Officer Dec 10, 2012 Sale $25.75 6,588 169,641 57,601 Dec 10, 2012, 06:17 PM
LIPPMAN MARC E Director Dec 05, 2012 Option Exercise $6.83 67,500 461,325 132,950 Dec 07, 2012, 07:28 PM
LIPPMAN MARC E Director Dec 05, 2012 Sale $25.54 67,500 1,723,950 117,950 Dec 07, 2012, 07:28 PM
Reynolds Thomas C Chief Medical Officer Dec 05, 2012 Option Exercise $12.16 10,000 121,600 67,601 Dec 06, 2012, 07:30 PM
Reynolds Thomas C Chief Medical Officer Dec 04, 2012 Option Exercise $12.11 30,000 363,200 67,601 Dec 06, 2012, 07:30 PM
Reynolds Thomas C Chief Medical Officer Dec 05, 2012 Sale $25.60 10,000 256,000 57,601 Dec 06, 2012, 07:30 PM
Reynolds Thomas C Chief Medical Officer Dec 04, 2012 Sale $25.58 30,000 767,500 57,601 Dec 06, 2012, 07:30 PM
WELCH DANIEL G Director Dec 03, 2012 Option Exercise $8.38 3,119 26,137 6,119 Dec 04, 2012, 07:44 PM
SIEGALL CLAY B President and CEO Dec 03, 2012 Option Exercise $3.30 8,250 27,225 1,179,211 Dec 04, 2012, 07:40 PM
SIEGALL CLAY B President and CEO Dec 03, 2012 Sale $25.19 8,250 207,777 1,170,961 Dec 04, 2012, 07:40 PM
Reynolds Thomas C Chief Medical Officer Dec 03, 2012 Option Exercise $12.16 10,000 121,600 67,601 Dec 03, 2012, 07:48 PM
Reynolds Thomas C Chief Medical Officer Nov 30, 2012 Option Exercise $12.01 10,000 120,084 67,078 Dec 03, 2012, 07:48 PM
Reynolds Thomas C Chief Medical Officer Nov 29, 2012 Option Exercise $12.00 20,000 240,000 67,601 Dec 03, 2012, 07:48 PM
Reynolds Thomas C Chief Medical Officer Dec 03, 2012 Sale $25.45 10,000 254,500 57,601 Dec 03, 2012, 07:48 PM
Reynolds Thomas C Chief Medical Officer Nov 30, 2012 Sale $25.50 10,000 255,000 57,601 Dec 03, 2012, 07:48 PM
Reynolds Thomas C Chief Medical Officer Nov 29, 2012 Sale $25.35 20,000 507,085 57,601 Dec 03, 2012, 07:48 PM
Reynolds Thomas C Chief Medical Officer Nov 26, 2012 Option Exercise $12.00 3,000 36,000 60,601 Nov 26, 2012, 06:58 PM
Reynolds Thomas C Chief Medical Officer Nov 23, 2012 Option Exercise $12.00 17,000 204,000 67,601 Nov 26, 2012, 06:58 PM
Reynolds Thomas C Chief Medical Officer Nov 21, 2012 Option Exercise $15.46 10,000 154,600 67,601 Nov 26, 2012, 06:58 PM
Reynolds Thomas C Chief Medical Officer Nov 26, 2012 Sale $25.50 3,000 76,500 57,601 Nov 26, 2012, 06:58 PM
Reynolds Thomas C Chief Medical Officer Nov 23, 2012 Sale $25.36 17,000 431,100 57,601 Nov 26, 2012, 06:58 PM
Reynolds Thomas C Chief Medical Officer Nov 21, 2012 Sale $25.25 10,000 252,500 57,601 Nov 26, 2012, 06:58 PM
Reynolds Thomas C Chief Medical Officer Nov 20, 2012 Option Exercise $15.17 10,000 151,714 66,767 Nov 20, 2012, 07:23 PM
Reynolds Thomas C Chief Medical Officer Nov 19, 2012 Option Exercise $15.46 10,000 154,600 67,601 Nov 20, 2012, 07:23 PM
Reynolds Thomas C Chief Medical Officer Nov 19, 2012 Sale $24.90 10,000 249,002 57,601 Nov 20, 2012, 07:23 PM
Reynolds Thomas C Chief Medical Officer Nov 20, 2012 Sale $25.00 10,000 250,000 57,601 Nov 20, 2012, 07:23 PM
DOBMEIER ERIC Chief Operating Officer Nov 13, 2012 Option Exercise $10.29 24,811 255,305 126,222 Nov 15, 2012, 07:16 PM
DOBMEIER ERIC Chief Operating Officer Nov 13, 2012 Sale $23.59 27,327 644,724 101,411 Nov 15, 2012, 07:16 PM
SIMPSON TODD E Chief Financial Officer Nov 08, 2012 Option Exercise $5.20 72,737 378,412 143,499 Nov 09, 2012, 06:03 PM
DOBMEIER ERIC Chief Operating Officer Nov 08, 2012 Option Exercise $6.45 34,575 223,107 103,927 Nov 09, 2012, 06:01 PM
SIEGALL CLAY B President and CEO Nov 01, 2012 Option Exercise $5.00 8,250 41,285 1,177,211 Nov 02, 2012, 05:23 PM
SIEGALL CLAY B President and CEO Nov 01, 2012 Sale $25.51 8,250 210,476 1,170,961 Nov 02, 2012, 05:23 PM
DOBMEIER ERIC Chief Operating Officer Oct 15, 2012 Option Exercise $10.29 25,000 257,250 94,352 Oct 16, 2012, 08:05 PM
DOBMEIER ERIC Chief Operating Officer Oct 15, 2012 Sale $25.01 25,000 625,295 69,352 Oct 16, 2012, 08:05 PM
SIEGALL CLAY B President and CEO Oct 01, 2012 Option Exercise $5.00 8,250 41,285 1,177,211 Oct 02, 2012, 08:23 PM
SIEGALL CLAY B President and CEO Oct 01, 2012 Sale $26.59 8,250 219,344 1,170,961 Oct 02, 2012, 08:23 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. Sep 10, 2012 Option Exercise $9.23 10,000 92,300 43,643 Sep 12, 2012, 06:26 PM
HIMES VAUGHN B EVP, Tech. Ops. & Proc. Sci. Sep 10, 2012 Sale $28.79 10,000 287,900 33,643 Sep 12, 2012, 06:26 PM
Reynolds Thomas C Chief Medical Officer Sep 06, 2012 Option Exercise $8.24 48,540 399,970 106,141 Sep 10, 2012, 08:02 PM
Reynolds Thomas C Chief Medical Officer Sep 06, 2012 Sale $29.75 48,540 1,444,065 57,601 Sep 10, 2012, 08:02 PM
SIMPSON TODD E Chief Financial Officer Sep 05, 2012 Option Exercise $11.16 45,000 502,073 112,937 Sep 07, 2012, 07:40 PM
SIMPSON TODD E Chief Financial Officer Sep 06, 2012 Option Exercise $12.16 50,000 608,000 120,762 Sep 07, 2012, 07:40 PM
SIMPSON TODD E Chief Financial Officer Sep 05, 2012 Sale $27.97 45,000 1,258,650 70,762 Sep 07, 2012, 07:40 PM
SIMPSON TODD E Chief Financial Officer Sep 06, 2012 Sale $28.97 50,000 1,448,500 70,762 Sep 07, 2012, 07:40 PM
SIEGALL CLAY B President and CEO Sep 04, 2012 Option Exercise $5.00 8,250 41,285 1,177,211 Sep 06, 2012, 07:51 PM
SIEGALL CLAY B President and CEO Sep 04, 2012 Sale $26.54 8,250 218,958 1,170,961 Sep 06, 2012, 07:51 PM
SIMPSON TODD E Chief Financial Officer Aug 24, 2012 Option Exercise $10.29 14,000 144,060 84,762 Aug 27, 2012, 07:55 PM
SIMPSON TODD E Chief Financial Officer Aug 27, 2012 Option Exercise $10.63 31,000 329,491 88,636 Aug 27, 2012, 07:55 PM
SIMPSON TODD E Chief Financial Officer Aug 24, 2012 Sale $26.97 14,000 377,580 70,762 Aug 27, 2012, 07:55 PM
SIMPSON TODD E Chief Financial Officer Aug 27, 2012 Sale $26.97 31,000 836,070 70,762 Aug 27, 2012, 07:55 PM
BERGER FRANKLIN M Director Aug 23, 2012 Option Exercise $10.14 20,000 202,800 183,720 Aug 27, 2012, 07:51 PM
SIMPSON TODD E Chief Financial Officer Aug 16, 2012 Option Exercise $10.29 40,000 411,600 90,762 Aug 20, 2012, 07:28 PM
SIMPSON TODD E Chief Financial Officer Aug 16, 2012 Sale $25.97 40,000 1,038,800 50,762 Aug 20, 2012, 07:28 PM
DOBMEIER ERIC Chief Operating Officer Aug 13, 2012 Sale $24.01 25,000 600,290 43,352 Aug 15, 2012, 04:30 PM
GRYSKA DAVID W Director Aug 10, 2012 Option Exercise $5.00 7,500 37,500 19,000 Aug 14, 2012, 04:31 PM
SIEGALL CLAY B President and CEO Aug 02, 2012 Option Exercise $3.30 458 1,511 1,097,169 Aug 03, 2012, 05:06 PM
SIEGALL CLAY B President and CEO Aug 01, 2012 Option Exercise $5.10 7,792 39,774 1,102,503 Aug 03, 2012, 05:06 PM
SIEGALL CLAY B President and CEO Aug 02, 2012 Sale $25.22 458 11,550 1,096,711 Aug 03, 2012, 05:06 PM
SIEGALL CLAY B President and CEO Aug 01, 2012 Sale $26.04 7,792 202,911 1,096,711 Aug 03, 2012, 05:06 PM
WELCH DANIEL G Director Jul 27, 2012 Option Exercise $19.02 3,000 57,060 3,000 Jul 31, 2012, 06:13 PM
SIEGALL CLAY B President & CEO Jul 02, 2012 Option Exercise $5.00 8,250 41,285 1,102,961 Jul 05, 2012, 04:59 PM
SIEGALL CLAY B President & CEO Jul 02, 2012 Sale $25.36 8,250 209,201 1,096,711 Jul 05, 2012, 04:59 PM
DOBMEIER ERIC Chief Operating Officer Jun 18, 2012 Option Exercise $10.29 25,000 257,250 93,073 Jun 20, 2012, 07:26 PM
DOBMEIER ERIC Chief Operating Officer Jun 18, 2012 Sale $25.36 25,000 634,000 68,073 Jun 20, 2012, 07:26 PM
ROSENBERG MORRIS EVP, Process Sciences Jun 12, 2012 Option Exercise $10.29 10,000 102,900 27,643 Jun 14, 2012, 07:51 PM
ROSENBERG MORRIS EVP, Process Sciences Jun 12, 2012 Sale $24.00 10,000 240,000 17,643 Jun 14, 2012, 07:51 PM
SIMPSON TODD E Chief Financial Officer Jun 12, 2012 Option Exercise $5.20 45,000 234,000 95,762 Jun 14, 2012, 07:49 PM
SIMPSON TODD E Chief Financial Officer Jun 14, 2012 Option Exercise $5.37 50,000 268,421 81,179 Jun 14, 2012, 07:49 PM
SIMPSON TODD E Chief Financial Officer Jun 14, 2012 Sale $24.97 50,000 1,248,500 50,762 Jun 14, 2012, 07:49 PM
SIMPSON TODD E Chief Financial Officer Jun 12, 2012 Sale $23.97 45,000 1,078,785 50,762 Jun 14, 2012, 07:49 PM
SIMPSON TODD E Chief Financial Officer Jun 08, 2012 Option Exercise $5.20 35,000 182,000 85,762 Jun 08, 2012, 07:45 PM
SIMPSON TODD E Chief Financial Officer Jun 08, 2012 Sale $22.97 35,000 803,950 50,762 Jun 08, 2012, 07:45 PM
ROSENBERG MORRIS EVP, Process Sciences Jun 07, 2012 Option Exercise $10.29 13,566 139,594 31,209 Jun 08, 2012, 07:43 PM
ROSENBERG MORRIS EVP, Process Sciences Jun 07, 2012 Sale $22.50 13,566 305,235 17,643 Jun 08, 2012, 07:43 PM
GRYSKA DAVID W Director Jun 05, 2012 Sale $19.75 8,000 158,000 11,500 Jun 06, 2012, 05:52 PM
ROSENBERG MORRIS EVP, Process Sciences May 16, 2012 Option Exercise $4.45 200 890 17,843 May 18, 2012, 07:00 PM
ROSENBERG MORRIS EVP, Process Sciences May 18, 2012 Option Exercise $4.45 64,800 288,360 65,419 May 18, 2012, 07:00 PM
ROSENBERG MORRIS EVP, Process Sciences May 16, 2012 Sale $20.80 200 4,160 17,643 May 18, 2012, 07:00 PM
ROSENBERG MORRIS EVP, Process Sciences May 18, 2012 Sale $21.54 64,800 1,395,616 17,643 May 18, 2012, 07:00 PM
Reynolds Thomas C Chief Medical Officer May 15, 2012 Option Exercise $8.24 949 7,820 32,022 May 17, 2012, 08:38 PM
Reynolds Thomas C Chief Medical Officer May 15, 2012 Sale $19.75 949 18,743 31,073 May 17, 2012, 08:38 PM
Reynolds Thomas C Chief Medical Officer Apr 25, 2012 Option Exercise $8.24 40,000 329,600 71,073 Apr 26, 2012, 07:44 PM
Reynolds Thomas C Chief Medical Officer Apr 25, 2012 Sale $19.75 40,000 790,000 31,073 Apr 26, 2012, 07:44 PM
DOBMEIER ERIC Chief Operating Officer Apr 25, 2012 Option Exercise $10.24 25,000 255,957 82,438 Apr 26, 2012, 07:39 PM
DOBMEIER ERIC Chief Operating Officer Apr 25, 2012 Sale $19.95 25,000 498,750 68,073 Apr 26, 2012, 07:39 PM
ROSENBERG MORRIS EVP, Process Sciences Apr 20, 2012 Option Exercise $5.63 38,281 215,522 55,924 Apr 24, 2012, 07:30 PM
ROSENBERG MORRIS EVP, Process Sciences Apr 20, 2012 Sale $19.51 38,281 746,862 17,643 Apr 24, 2012, 07:30 PM
ROSENBERG MORRIS EVP, Process Sciences Apr 17, 2012 Option Exercise $5.83 44,219 257,653 46,080 Apr 19, 2012, 04:01 PM
ROSENBERG MORRIS EVP, Process Sciences Apr 17, 2012 Sale $18.88 44,219 834,855 17,643 Apr 19, 2012, 04:01 PM
Reynolds Thomas C Chief Medical Officer Mar 22, 2012 Option Exercise $8.24 40,000 329,600 71,073 Mar 23, 2012, 05:25 PM
Reynolds Thomas C Chief Medical Officer Mar 22, 2012 Sale $19.78 40,000 791,100 31,073 Mar 23, 2012, 05:25 PM
LIPPMAN MARC E Director Mar 19, 2012 Option Exercise $4.97 7,500 37,275 117,950 Mar 20, 2012, 07:21 PM
Reynolds Thomas C Chief Medical Officer Mar 19, 2012 Option Exercise $8.24 37,700 310,648 68,773 Mar 20, 2012, 07:19 PM
Reynolds Thomas C Chief Medical Officer Mar 16, 2012 Option Exercise $8.24 2,300 18,952 33,373 Mar 20, 2012, 07:19 PM
Reynolds Thomas C Chief Medical Officer Mar 19, 2012 Sale $19.75 37,700 744,575 31,073 Mar 20, 2012, 07:19 PM
Reynolds Thomas C Chief Medical Officer Mar 16, 2012 Sale $19.75 2,300 45,425 31,073 Mar 20, 2012, 07:19 PM
ROSENBERG MORRIS EVP, Process Sciences Mar 13, 2012 Option Exercise $6.72 69,626 468,168 54,204 Mar 15, 2012, 04:37 PM
ROSENBERG MORRIS EVP, Process Sciences Mar 13, 2012 Sale $18.59 69,626 1,294,173 17,643 Mar 15, 2012, 04:37 PM
DOBMEIER ERIC Chief Operating Officer Feb 28, 2012 Sale $18.53 4,000 74,114 68,073 Mar 01, 2012, 05:17 PM
DOBMEIER ERIC Chief Operating Officer Feb 28, 2012 Option Exercise $10.25 46,000 471,570 99,844 Feb 29, 2012, 06:32 PM
DOBMEIER ERIC Chief Operating Officer Feb 28, 2012 Sale $18.52 46,000 851,938 72,073 Feb 29, 2012, 06:32 PM
Reynolds Thomas C Chief Medical Officer Jan 27, 2012 Option Exercise $8.24 40,000 329,600 70,169 Jan 30, 2012, 07:33 PM
Reynolds Thomas C Chief Medical Officer Jan 27, 2012 Sale $19.75 40,000 790,000 30,169 Jan 30, 2012, 07:33 PM
SIEGALL CLAY B President and CEO Jan 03, 2012 Option Exercise $6.34 15,000 95,100 1,060,055 Jan 05, 2012, 08:27 PM
SIEGALL CLAY B President and CEO Jan 03, 2012 Sale $16.73 15,000 250,959 1,045,055 Jan 05, 2012, 08:27 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Dec 30, 2011 Option Exercise $6.25 355,143 2,219,644 15,131,223 Jan 04, 2012, 07:25 PM
Baker Bros. Capital (GP), LLC Director Dec 30, 2011 Option Exercise $6.25 68,006 425,038 539,130 Jan 04, 2012, 07:24 PM
Baker Biotech Capital (GP), LLC Director Dec 30, 2011 Option Exercise $6.25 339,788 2,123,675 4,966,001 Jan 04, 2012, 07:24 PM
Baker / Tisch Capital (GP), LLC Director Dec 30, 2011 Option Exercise $6.25 49,563 309,769 450,461 Jan 04, 2012, 07:23 PM
DOBMEIER ERIC Chief Operating Officer Dec 22, 2011 Option Exercise $4.45 10,000 44,500 71,843 Dec 22, 2011, 05:29 PM
LIPPMAN MARC E Director Dec 14, 2011 Option Exercise $6.40 6,875 44,000 110,450 Dec 16, 2011, 08:28 PM
GRYSKA DAVID W Director Dec 15, 2011 Option Exercise $5.00 4,500 22,500 19,500 Dec 16, 2011, 08:24 PM
GRYSKA DAVID W Director Dec 09, 2011 Sale $18.09 10,000 180,917 15,000 Dec 13, 2011, 06:53 PM
SIEGALL CLAY B President and CEO Dec 01, 2011 Option Exercise $6.34 15,000 95,100 1,060,055 Dec 02, 2011, 06:35 PM
SIEGALL CLAY B President and CEO Dec 01, 2011 Sale $15.97 15,000 239,596 1,045,055 Dec 02, 2011, 06:35 PM
DOBMEIER ERIC Chief Operating Officer Nov 09, 2011 Option Exercise $5.25 2,516 13,209 61,843 Nov 10, 2011, 07:52 PM
SIEGALL CLAY B President and CEO Nov 01, 2011 Option Exercise $6.34 15,000 95,100 1,060,055 Nov 03, 2011, 08:08 PM
SIEGALL CLAY B President and CEO Nov 01, 2011 Sale $21.89 15,000 328,413 1,045,055 Nov 03, 2011, 08:08 PM
DOBMEIER ERIC Chief Operating Officer Oct 27, 2011 Option Exercise $5.87 20,918 122,725 70,162 Oct 27, 2011, 07:58 PM
DOBMEIER ERIC Chief Operating Officer Oct 27, 2011 Sale $21.95 20,918 459,150 59,327 Oct 27, 2011, 07:58 PM
DOBMEIER ERIC Chief Operating Officer Oct 20, 2011 Option Exercise $6.74 20,461 137,907 79,788 Oct 21, 2011, 06:45 PM
DOBMEIER ERIC Chief Operating Officer Oct 20, 2011 Sale $20.58 20,461 421,024 59,327 Oct 21, 2011, 06:45 PM
SIMPSON TODD E Chief Financial Officer Oct 07, 2011 Option Exercise $5.20 24,350 126,620 73,592 Oct 07, 2011, 07:14 PM
SIMPSON TODD E Chief Financial Officer Oct 07, 2011 Sale $21.97 24,350 534,969 49,242 Oct 07, 2011, 07:14 PM
SIEGALL CLAY B President and CEO Oct 04, 2011 Option Exercise $6.34 15,000 95,100 1,060,055 Oct 06, 2011, 07:19 PM
SIEGALL CLAY B President and CEO Oct 04, 2011 Sale $20.15 15,000 302,283 1,045,055 Oct 06, 2011, 07:19 PM
SIEGALL CLAY B President and CEO Sep 21, 2011 Option Exercise $6.34 24,400 154,696 1,069,455 Sep 21, 2011, 08:49 PM
SIEGALL CLAY B President and CEO Sep 20, 2011 Option Exercise $6.34 5,600 35,504 1,050,655 Sep 21, 2011, 08:49 PM
SIEGALL CLAY B President and CEO Sep 21, 2011 Sale $20.15 24,400 491,711 1,045,055 Sep 21, 2011, 08:49 PM
SIEGALL CLAY B President and CEO Sep 20, 2011 Sale $20.00 5,600 112,007 1,045,055 Sep 21, 2011, 08:49 PM
MCLAUGHLIN JOHN PETER Director Sep 09, 2011 Option Exercise $9.82 25,000 245,500 25,000 Sep 13, 2011, 05:04 PM
14159 capital (GP), LLC Director Sep 06, 2011 Buy $17.08 1,773 30,285 323,148 Sep 08, 2011, 05:13 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Sep 06, 2011 Buy $17.08 129,187 2,206,641 14,776,080 Sep 08, 2011, 05:12 PM
SIEGALL CLAY B President and CEO Sep 02, 2011 Option Exercise $3.30 16,251 53,628 1,045,055 Sep 06, 2011, 08:40 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Aug 25, 2011 Buy $15.49 984,850 15,253,844 14,646,893 Aug 25, 2011, 05:37 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Aug 24, 2011 Buy $14.98 9,576 143,432 13,662,043 Aug 25, 2011, 05:37 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Aug 23, 2011 Buy $14.79 171,009 2,528,388 13,652,467 Aug 25, 2011, 05:37 PM
14159 capital (GP), LLC Director Aug 25, 2011 Buy $15.49 15,150 234,651 321,375 Aug 25, 2011, 05:36 PM
14159 capital (GP), LLC Director Aug 24, 2011 Buy $14.98 147 2,202 306,225 Aug 25, 2011, 05:36 PM
14159 capital (GP), LLC Director Aug 23, 2011 Buy $14.79 2,629 38,870 306,078 Aug 25, 2011, 05:36 PM
Reynolds Thomas C Chief Medical Officer Aug 01, 2011 Sale $17.37 1,539 26,732 1,488 Aug 03, 2011, 07:27 PM
DOBMEIER ERIC Chief Operating Officer Aug 01, 2011 Option Exercise $5.25 25,000 131,250 33,817 Aug 03, 2011, 07:21 PM
SIMPSON TODD E Chief Financial Officer Jul 18, 2011 Option Exercise $4.63 18,663 86,500 28,022 Jul 20, 2011, 07:21 PM
SIEGALL CLAY B President and CEO Jul 01, 2011 Option Exercise $6.34 15,000 95,100 965,667 Jul 01, 2011, 07:07 PM
SIEGALL CLAY B President and CEO Jul 01, 2011 Sale $20.66 15,000 309,865 950,667 Jul 01, 2011, 07:07 PM
BERGER FRANKLIN M Director Jun 22, 2011 Buy $20.04 7,000 140,274 163,720 Jun 23, 2011, 03:38 PM
SIEGALL CLAY B President and CEO Jun 20, 2011 Option Exercise $6.34 9,000 57,060 959,667 Jun 21, 2011, 06:37 PM
SIEGALL CLAY B President and CEO Jun 20, 2011 Sale $20.01 9,000 180,071 950,667 Jun 21, 2011, 06:37 PM
DOBMEIER ERIC Chief Operating Officer Jun 20, 2011 Sale $20.00 13,385 267,700 8,817 Jun 21, 2011, 06:35 PM
SIEGALL CLAY B President and CEO Jun 09, 2011 Option Exercise $6.34 1,000 6,340 951,667 Jun 13, 2011, 07:42 PM
SIEGALL CLAY B President and CEO Jun 09, 2011 Sale $20.00 1,000 20,000 950,667 Jun 13, 2011, 07:42 PM
DOBMEIER ERIC Chief Business Officer Jun 09, 2011 Sale $20.00 3,600 72,000 22,202 Jun 13, 2011, 07:40 PM
SIMPSON TODD E Chief Financial Officer Jun 07, 2011 Option Exercise $5.20 10,750 55,900 20,109 Jun 09, 2011, 08:31 PM
SIMPSON TODD E Chief Financial Officer Jun 07, 2011 Sale $19.96 10,750 214,570 9,359 Jun 09, 2011, 08:31 PM
ROSENBERG MORRIS EVP, Process Sciences Jun 07, 2011 Option Exercise $6.34 2,503 15,869 2,503 Jun 09, 2011, 08:12 PM
ROSENBERG MORRIS EVP, Process Sciences Jun 07, 2011 Sale $19.67 2,503 49,243 0 Jun 09, 2011, 08:12 PM
ROSENBERG MORRIS EVP, Process Sciences May 27, 2011 Option Exercise $6.34 17,497 110,931 17,497 Jun 01, 2011, 07:07 PM
ROSENBERG MORRIS EVP, Process Sciences May 27, 2011 Sale $19.50 17,497 341,192 0 Jun 01, 2011, 07:07 PM
Reynolds Thomas C Chief Medical Officer May 19, 2011 Option Exercise $11.09 14,585 161,748 9,693 May 20, 2011, 06:39 PM
Reynolds Thomas C Chief Medical Officer May 18, 2011 Option Exercise $11.09 5,413 60,030 8,440 May 20, 2011, 06:39 PM
Reynolds Thomas C Chief Medical Officer May 18, 2011 Sale $18.70 5,413 101,223 3,027 May 20, 2011, 06:39 PM
Reynolds Thomas C Chief Medical Officer May 19, 2011 Sale $18.71 14,585 272,885 3,027 May 20, 2011, 06:39 PM
SIEGALL CLAY B President and CEO May 18, 2011 Option Exercise $6.34 5,000 31,700 950,667 May 20, 2011, 06:36 PM
ROSENBERG MORRIS EVP, Process Sciences May 19, 2011 Option Exercise $6.34 20,000 126,800 20,000 May 20, 2011, 06:33 PM
ROSENBERG MORRIS EVP, Process Sciences May 19, 2011 Sale $18.80 20,000 376,000 0 May 20, 2011, 06:33 PM
SIMPSON TODD E Chief Financial Officer May 18, 2011 Option Exercise $4.95 21,250 105,110 23,422 May 20, 2011, 06:31 PM
SIMPSON TODD E Chief Financial Officer May 18, 2011 Sale $18.64 21,250 396,100 9,359 May 20, 2011, 06:31 PM
ROSENBERG MORRIS EVP, Process Sciences May 13, 2011 Option Exercise $6.34 20,000 126,800 20,000 May 13, 2011, 07:27 PM
ROSENBERG MORRIS EVP, Process Sciences May 13, 2011 Sale $17.80 20,000 356,000 0 May 13, 2011, 07:27 PM
Reynolds Thomas C Chief Medical Officer May 13, 2011 Option Exercise $8.24 20,000 164,800 8,027 May 13, 2011, 07:25 PM
Reynolds Thomas C Chief Medical Officer May 13, 2011 Sale $17.80 20,000 356,000 3,027 May 13, 2011, 07:25 PM
DOBMEIER ERIC Chief Business Officer May 13, 2011 Option Exercise $5.89 42,715 251,382 54,967 May 13, 2011, 07:22 PM
DOBMEIER ERIC Chief Business Officer May 13, 2011 Sale $18.00 42,715 768,870 25,802 May 13, 2011, 07:22 PM
SIMPSON TODD E Chief Financial Officer May 09, 2011 Option Exercise $4.45 20,000 89,000 29,359 May 11, 2011, 05:00 PM
SIMPSON TODD E Chief Financial Officer May 09, 2011 Sale $17.74 20,000 354,800 9,359 May 11, 2011, 05:00 PM
SIEGALL CLAY B President and CEO May 09, 2011 Option Exercise $8.43 50,000 421,500 995,667 May 11, 2011, 04:58 PM
SIEGALL CLAY B President and CEO May 09, 2011 Sale $17.35 50,000 867,705 945,667 May 11, 2011, 04:58 PM
SIMPSON TODD E Chief Financial Officer Apr 29, 2011 Option Exercise $4.45 15,000 66,750 24,359 May 03, 2011, 06:49 PM
SIMPSON TODD E Chief Financial Officer Apr 29, 2011 Sale $16.94 15,000 254,100 9,359 May 03, 2011, 06:49 PM
Reynolds Thomas C Chief Medical Officer Apr 29, 2011 Option Exercise $8.24 9,999 82,392 6,360 May 03, 2011, 06:47 PM
Reynolds Thomas C Chief Medical Officer Apr 29, 2011 Sale $16.95 11,915 201,959 4,114 May 03, 2011, 06:47 PM
SIEGALL CLAY B President and CEO May 02, 2011 Option Exercise $8.43 50,000 421,500 995,667 May 03, 2011, 06:44 PM
SIEGALL CLAY B President and CEO May 02, 2011 Sale $17.43 50,000 871,355 945,667 May 03, 2011, 06:44 PM
ROSENBERG MORRIS EVP, Process Sciences May 02, 2011 Option Exercise $6.72 12,500 84,000 12,500 May 03, 2011, 06:42 PM
ROSENBERG MORRIS EVP, Process Sciences Apr 29, 2011 Option Exercise $6.72 12,500 84,000 12,500 May 03, 2011, 06:42 PM
ROSENBERG MORRIS EVP, Process Sciences May 02, 2011 Sale $17.50 12,500 218,751 0 May 03, 2011, 06:42 PM
ROSENBERG MORRIS EVP, Process Sciences Apr 29, 2011 Sale $16.80 12,500 210,000 0 May 03, 2011, 06:42 PM
SIEGALL CLAY B President and CEO Apr 14, 2011 Option Exercise $8.43 50,000 421,500 995,667 Apr 15, 2011, 06:49 PM
SIEGALL CLAY B President and CEO Apr 14, 2011 Sale $15.27 50,000 763,455 945,667 Apr 15, 2011, 06:49 PM
SIEGALL CLAY B President and CEO Apr 07, 2011 Option Exercise $8.43 50,000 421,500 995,667 Apr 08, 2011, 07:25 PM
SIEGALL CLAY B President and CEO Apr 07, 2011 Sale $16.06 50,000 802,905 945,667 Apr 08, 2011, 07:25 PM
DOBMEIER ERIC Chief Business Officer Apr 05, 2011 Option Exercise $5.49 40,000 219,484 42,169 Apr 07, 2011, 07:55 PM
DOBMEIER ERIC Chief Business Officer Apr 05, 2011 Sale $16.00 40,000 640,000 25,802 Apr 07, 2011, 07:55 PM
SIEGALL CLAY B President and CEO Mar 17, 2011 Option Exercise $8.43 200,000 1,686,000 1,133,805 Mar 18, 2011, 07:11 PM
SIEGALL CLAY B President and CEO Mar 17, 2011 Sale $14.09 200,000 2,817,280 945,667 Mar 18, 2011, 07:11 PM
14159 capital (GP), LLC Director Feb 02, 2011 Buy $15.50 48,197 747,054 303,449 Feb 04, 2011, 04:53 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Feb 02, 2011 Buy $15.50 1,751,803 27,152,947 13,470,692 Feb 04, 2011, 04:48 PM
DOBMEIER ERIC Chief Business Officer Dec 22, 2010 Option Exercise $5.25 4,000 21,000 24,242 Dec 23, 2010, 06:10 PM
ROSENBERG MORRIS EVP, Process Sciences Dec 15, 2010 Option Exercise $6.72 25,000 168,000 25,000 Dec 17, 2010, 07:00 PM
ROSENBERG MORRIS EVP, Process Sciences Dec 15, 2010 Sale $16.22 25,000 405,490 0 Dec 17, 2010, 07:00 PM
ROSENBERG MORRIS EVP, Process Sciences Dec 02, 2010 Option Exercise $6.72 25,000 168,000 10,000 Dec 03, 2010, 07:26 PM
ROSENBERG MORRIS EVP, Process Sciences Dec 02, 2010 Sale $15.81 25,000 395,295 0 Dec 03, 2010, 07:26 PM
GRYSKA DAVID W Director Nov 12, 2010 Option Exercise $5.00 4,000 20,000 25,500 Nov 16, 2010, 05:08 PM
ROSENBERG MORRIS EVP, Process Sciences Nov 04, 2010 Option Exercise $6.72 25,000 168,000 25,000 Nov 05, 2010, 07:30 PM
ROSENBERG MORRIS EVP, Process Sciences Nov 04, 2010 Sale $14.70 25,000 367,390 0 Nov 05, 2010, 07:30 PM
Reynolds Thomas C Chief Medical Officer Oct 11, 2010 Option Exercise $8.24 25,000 206,000 30,719 Oct 12, 2010, 07:49 PM
Reynolds Thomas C Chief Medical Officer Oct 11, 2010 Sale $16.95 25,000 423,750 5,719 Oct 12, 2010, 07:49 PM
BERGER FRANKLIN M Director Oct 01, 2010 Option Exercise $8.38 5,000 41,900 156,720 Oct 01, 2010, 07:55 PM
Reynolds Thomas C Chief Medical Officer Sep 27, 2010 Option Exercise $8.24 25,000 206,000 30,719