Opko Health Inc. (OPK) NASDAQ
$1.30 0.04 (2.78%)
Market Cap: $973.54M
As of 03/24/23 03:45 PM EDT. Market open.
Opko Health Inc. (OPK)
NASDAQ
$1.30
0.04 (2.78%)
Market Cap: $973.54M
As of 03/24/23 03:45 PM EDT. Market open.
Opko Health Inc. is a multinational biopharmaceutical and diagnostics company that seeks to establish industry-leading positions in large, rapidly growing markets by leveraging its discovery, development, and commercialization expertise and novel and proprietary ... read more
Opko Health Inc. is a multinational biopharmaceutical and diagnostics company that seeks to establish industry-leading positions in large, rapidly growing markets by leveraging its discovery, development, and commercialization expertise and novel and proprietary technologies. read less
COMPANY PROFILE
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
Phillip Frost
Full Time Employees
5,767
CEO Compensation (Base)
$960,000
CEO Compensation (Total)
$2.04M
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
Phillip Frost
Full Time Employees
5,767
CEO Compensation (Base)
$960,000
CEO Compensation (Total)
$2.04M
URL
Address
4400 Biscayne Blvd, Florida, Miami, 33137.
PRICE CHART FOR OPKO HEALTH INC
From:
To:
NEWS
KEY STATS
Open
$1.26
Previous Close
$1.26
Days Range
$1.25 - $1.36
52 week range
$1 - $3.75
Volume
1,269,978
Avg. Volume (30 days)
4,745,832
Market Cap
$973.54M
Dividend Yield
0.00%
P/E
-2.96
Shares Outstanding
772,650,812
Open
$1.26
Previous Close
$1.26
Days Range
$1.25 - $1.36
52 week range
$1 - $3.75
Volume
1,269,978
Avg. Volume (30 days)
4,745,832
Market Cap
$973.54M
Dividend Yield
0.00%
P/E
-2.96
Shares Outstanding
772,650,812
Open in: 
Open in:
INSIDER TRANSACTIONS FOR OPKO HEALTH INC
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 22, 2023 | Buy | $1.32 | 200,000 | 264,294 | 200,031,694 | Mar 23, 2023, 06:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 08, 2023 | Buy | $1.18 | 1,000,000 | 1,175,384 | 199,831,694 | Mar 09, 2023, 06:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 22, 2022 | Buy | $1.49 | 300,000 | 446,673 | 198,831,694 | Nov 23, 2022, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 09, 2022 | Buy | $1.60 | 196,488 | 313,840 | 198,531,694 | Nov 10, 2022, 06:56 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 09, 2022 | Buy | $1.59 | 3,512 | 5,584 | 198,431,694 | Nov 10, 2022, 06:56 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 27, 2022 | Buy | $1.82 | 100,000 | 182,006 | 198,331,694 | Oct 28, 2022, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 19, 2022 | Buy | $1.72 | 100,000 | 172,069 | 198,231,694 | Oct 20, 2022, 06:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 14, 2022 | Buy | $1.72 | 100,000 | 171,917 | 198,131,694 | Oct 17, 2022, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 13, 2022 | Buy | $1.79 | 100,000 | 179,367 | 198,031,694 | Oct 14, 2022, 06:57 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 12, 2022 | Buy | $1.73 | 100,000 | 172,722 | 197,931,694 | Oct 13, 2022, 07:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 07, 2022 | Buy | $1.77 | 75,000 | 132,624 | 197,831,694 | Oct 11, 2022, 07:47 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 26, 2022 | Buy | $1.80 | 50,000 | 89,979 | 197,756,694 | Sep 27, 2022, 07:29 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 23, 2022 | Buy | $1.85 | 50,000 | 92,313 | 197,706,694 | Sep 26, 2022, 06:59 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 22, 2022 | Buy | $1.90 | 50,000 | 94,837 | 197,656,694 | Sep 23, 2022, 07:20 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 21, 2022 | Buy | $1.91 | 50,000 | 95,492 | 197,606,694 | Sep 22, 2022, 07:39 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 20, 2022 | Buy | $1.94 | 50,000 | 96,888 | 197,556,694 | Sep 21, 2022, 07:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 19, 2022 | Buy | $1.97 | 50,000 | 98,554 | 197,506,694 | Sep 20, 2022, 07:20 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 15, 2022 | Buy | $2.06 | 200,000 | 412,900 | 197,456,694 | Sep 16, 2022, 07:42 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 02, 2022 | Buy | $2.14 | 100,000 | 214,138 | 197,256,694 | Sep 06, 2022, 07:50 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 17, 2022 | Buy | $2.54 | 200,000 | 507,949 | 197,156,694 | Aug 18, 2022, 08:22 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 05, 2022 | Buy | $2.29 | 350,000 | 802,103 | 196,956,694 | Aug 08, 2022, 08:05 AM |
| Nabel Gary J. | Chief Innovation Officer | Jun 22, 2022 | Buy | $2.47 | 80,000 | 197,600 | 80,000 | Jun 24, 2022, 07:52 PM |
| Nabel Gary J. | Chief Innovation Officer | Jun 22, 2022 | Buy | $2.50 | 80,000 | 199,807 | 19,857,514 | Jun 24, 2022, 07:52 PM |
| Nabel Gary J. | Chief Innovation Officer | Jun 22, 2022 | Buy | $2.50 | 80,000 | 199,986 | 19,857,514 | Jun 24, 2022, 07:52 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 21, 2022 | Buy | $2.39 | 200,000 | 478,857 | 196,606,694 | Jun 22, 2022, 06:59 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 16, 2022 | Buy | $2.31 | 100,000 | 231,327 | 196,406,694 | Jun 17, 2022, 08:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 13, 2022 | Buy | $2.36 | 100,000 | 236,498 | 196,306,694 | Jun 14, 2022, 08:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 06, 2022 | Buy | $2.79 | 100,000 | 279,227 | 196,206,694 | Jun 07, 2022, 07:29 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 01, 2022 | Buy | $2.95 | 50,000 | 147,614 | 196,106,694 | Jun 02, 2022, 08:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 31, 2022 | Buy | $3.02 | 50,000 | 151,177 | 196,056,694 | Jun 01, 2022, 07:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 25, 2022 | Buy | $2.98 | 50,000 | 148,866 | 196,006,694 | May 26, 2022, 08:16 AM |
| Nabel Gary J. | Chief Innovation Officer | May 18, 2022 | Buy | $2.90 | 68,492 | 198,627 | 75,471 | May 19, 2022, 04:28 PM |
| Nabel Gary J. | Chief Innovation Officer | May 12, 2022 | Buy | $2.65 | 6,979 | 18,494 | 6,979 | May 19, 2022, 04:28 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 18, 2022 | Buy | $2.88 | 50,000 | 143,984 | 195,956,694 | May 19, 2022, 07:32 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 16, 2022 | Buy | $2.98 | 150,000 | 446,794 | 195,906,694 | May 17, 2022, 06:33 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 13, 2022 | Buy | $3.00 | 200,000 | 599,316 | 195,756,694 | May 16, 2022, 07:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 11, 2022 | Buy | $2.83 | 400,000 | 1,132,400 | 195,556,694 | May 12, 2022, 06:50 AM |
| Zerhouni Elias A. | Vice Chairman and President | May 10, 2022 | Buy | $2.79 | 89,600 | 250,396 | 89,600 | May 11, 2022, 09:01 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 10, 2022 | Buy | $2.78 | 400,000 | 1,113,560 | 195,156,694 | May 11, 2022, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 14, 2022 | Buy | $3.04 | 35,000 | 106,317 | 194,756,694 | Mar 15, 2022, 07:33 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 11, 2022 | Buy | $3.13 | 100,000 | 312,865 | 194,721,694 | Mar 14, 2022, 07:16 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 28, 2022 | Buy | $3.11 | 100,000 | 310,796 | 194,621,694 | Mar 01, 2022, 07:33 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 25, 2022 | Buy | $3.09 | 750,000 | 2,315,325 | 194,521,694 | Feb 28, 2022, 07:59 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 14, 2022 | Buy | $3.04 | 100,000 | 303,569 | 193,771,694 | Feb 15, 2022, 09:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 01, 2022 | Buy | $3.03 | 150,000 | 455,009 | 193,671,694 | Feb 02, 2022, 07:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 26, 2022 | Buy | $2.98 | 350,000 | 1,041,817 | 193,521,694 | Jan 27, 2022, 08:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 14, 2021 | Buy | $3.46 | 100,000 | 346,443 | 193,171,694 | Sep 15, 2021, 07:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 13, 2021 | Buy | $3.69 | 100,000 | 368,987 | 193,071,694 | Aug 16, 2021, 08:33 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Aug 09, 2021 | Buy | $3.73 | 10 | 37 | 27,599,870 | Aug 10, 2021, 04:12 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 14, 2021 | Buy | $3.62 | 200,000 | 723,927 | 192,971,694 | Jun 15, 2021, 07:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 10, 2021 | Buy | $3.65 | 75,000 | 273,745 | 192,371,694 | May 11, 2021, 07:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 06, 2021 | Buy | $3.91 | 25,000 | 97,783 | 192,221,694 | May 07, 2021, 07:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 04, 2021 | Buy | $3.94 | 25,000 | 98,481 | 192,196,694 | May 05, 2021, 07:59 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 05, 2021 | Buy | $3.91 | 300,000 | 1,173,841 | 192,171,694 | Mar 08, 2021, 07:20 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 19, 2021 | Buy | $4.77 | 500,000 | 2,383,455 | 191,871,694 | Feb 22, 2021, 07:37 AM |
| Fishel Robert Scott | Director | Jan 25, 2021 | Option Exercise | $2.70 | 60,000 | 162,200 | 60,000 | Jan 26, 2021, 04:07 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 28, 2020 | Buy | $4.00 | 300,000 | 1,199,500 | 191,371,694 | Dec 29, 2020, 07:33 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 09, 2020 | Buy | $3.18 | 250,000 | 794,669 | 191,071,694 | Nov 10, 2020, 06:53 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 30, 2020 | Buy | $3.45 | 600,000 | 2,072,820 | 190,821,694 | Nov 02, 2020, 06:57 AM |
| Rubin Steven D | Executive VP-Administration | Aug 26, 2020 | Buy | $3.99 | 10,000 | 39,943 | 6,167,732 | Aug 27, 2020, 08:40 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 03, 2020 | Buy | $2.27 | 100,000 | 227,000 | 190,221,694 | Jun 04, 2020, 07:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 02, 2020 | Buy | $2.42 | 100,000 | 242,410 | 190,121,694 | Jun 03, 2020, 07:54 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 28, 2020 | Buy | $2.16 | 100,000 | 215,975 | 190,021,694 | May 29, 2020, 07:21 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 26, 2020 | Buy | $2.35 | 250,000 | 587,986 | 189,921,694 | May 27, 2020, 08:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 07, 2020 | Buy | $2.08 | 400,000 | 831,606 | 189,671,694 | May 08, 2020, 07:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 17, 2020 | Buy | $1.66 | 325,000 | 540,364 | 189,271,694 | Apr 20, 2020, 08:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 16, 2020 | Buy | $1.63 | 25,000 | 40,738 | 188,946,694 | Apr 17, 2020, 08:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 15, 2020 | Buy | $1.55 | 200,000 | 309,377 | 188,921,694 | Apr 16, 2020, 08:20 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 07, 2020 | Buy | $1.28 | 400,000 | 510,984 | 188,721,694 | Apr 08, 2020, 08:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 03, 2020 | Buy | $1.15 | 50,000 | 57,592 | 188,321,694 | Apr 06, 2020, 08:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 02, 2020 | Buy | $1.16 | 500,000 | 581,185 | 188,271,694 | Apr 03, 2020, 07:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 01, 2020 | Buy | $1.23 | 643,549 | 793,012 | 187,771,694 | Apr 02, 2020, 08:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 30, 2020 | Buy | $1.35 | 161,968 | 218,037 | 187,128,145 | Mar 31, 2020, 08:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 27, 2020 | Buy | $1.40 | 100,000 | 139,975 | 186,966,177 | Mar 30, 2020, 08:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 26, 2020 | Buy | $1.38 | 200,000 | 275,445 | 186,866,177 | Mar 27, 2020, 08:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 19, 2020 | Buy | $1.49 | 100,000 | 148,871 | 186,666,177 | Mar 20, 2020, 07:44 AM |
| Japour Anthony J | Director | Mar 12, 2020 | Buy | $1.51 | 500 | 755 | 1,000 | Mar 13, 2020, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 10, 2020 | Buy | $1.61 | 300,000 | 481,636 | 186,566,177 | Mar 11, 2020, 09:45 AM |
| Japour Anthony J | Director | Mar 03, 2020 | Buy | $1.47 | 500 | 735 | 500 | Mar 04, 2020, 01:51 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 03, 2020 | Buy | $1.47 | 100,000 | 147,000 | 170,031,230 | Mar 04, 2020, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 02, 2020 | Buy | $1.49 | 100,000 | 148,978 | 169,931,230 | Mar 03, 2020, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 28, 2020 | Buy | $1.46 | 125,000 | 182,099 | 169,831,230 | Mar 02, 2020, 06:47 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 27, 2020 | Buy | $1.48 | 250,000 | 369,816 | 169,706,230 | Feb 28, 2020, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 14, 2020 | Buy | $1.57 | 100,000 | 157,291 | 169,456,230 | Feb 18, 2020, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 13, 2020 | Buy | $1.58 | 100,000 | 158,000 | 169,356,230 | Feb 14, 2020, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 11, 2020 | Buy | $1.59 | 14,239 | 22,640 | 169,256,230 | Feb 12, 2020, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 06, 2020 | Buy | $1.53 | 50,000 | 76,500 | 169,241,991 | Feb 07, 2020, 07:20 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 31, 2020 | Buy | $1.43 | 50,000 | 71,750 | 169,191,991 | Feb 03, 2020, 06:53 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 30, 2020 | Buy | $1.47 | 100,000 | 147,000 | 169,141,991 | Jan 31, 2020, 07:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 24, 2020 | Buy | $1.58 | 50,000 | 79,000 | 169,041,991 | Jan 27, 2020, 06:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 23, 2020 | Buy | $1.63 | 50,000 | 81,500 | 168,991,991 | Jan 24, 2020, 07:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 17, 2020 | Buy | $1.56 | 22,262 | 34,729 | 168,941,991 | Jan 21, 2020, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 13, 2020 | Buy | $1.44 | 50,000 | 72,000 | 168,919,729 | Jan 14, 2020, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 10, 2020 | Buy | $1.48 | 50,000 | 74,000 | 168,869,729 | Jan 13, 2020, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 08, 2020 | Buy | $1.47 | 50,000 | 73,500 | 168,819,729 | Jan 09, 2020, 06:53 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 30, 2019 | Buy | $1.46 | 100,000 | 146,000 | 168,769,729 | Dec 31, 2019, 08:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 27, 2019 | Buy | $1.52 | 100,000 | 152,500 | 168,669,729 | Dec 30, 2019, 07:44 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 19, 2019 | Buy | $1.48 | 100,000 | 148,229 | 168,569,729 | Dec 20, 2019, 06:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 18, 2019 | Buy | $1.50 | 150,000 | 224,750 | 168,469,729 | Dec 19, 2019, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 17, 2019 | Buy | $1.54 | 75,000 | 115,375 | 168,319,729 | Dec 18, 2019, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 11, 2019 | Buy | $1.50 | 100,000 | 150,172 | 168,244,729 | Dec 12, 2019, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 09, 2019 | Buy | $1.59 | 50,000 | 79,500 | 168,144,729 | Dec 10, 2019, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 05, 2019 | Buy | $1.60 | 50,000 | 80,000 | 168,094,729 | Dec 06, 2019, 06:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 03, 2019 | Buy | $1.60 | 10,286 | 16,458 | 168,044,729 | Dec 04, 2019, 06:38 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 02, 2019 | Buy | $1.56 | 50,000 | 77,755 | 168,034,443 | Dec 03, 2019, 07:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 26, 2019 | Buy | $1.55 | 100,000 | 154,500 | 167,984,443 | Nov 27, 2019, 06:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 19, 2019 | Buy | $1.47 | 100,000 | 146,651 | 167,884,443 | Nov 20, 2019, 06:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 18, 2019 | Buy | $1.48 | 100,000 | 147,925 | 167,784,443 | Nov 19, 2019, 06:22 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 13, 2019 | Buy | $1.42 | 50,000 | 71,190 | 167,684,443 | Nov 14, 2019, 07:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 12, 2019 | Buy | $1.44 | 200,000 | 288,124 | 167,634,443 | Nov 13, 2019, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 08, 2019 | Buy | $1.48 | 50,000 | 74,058 | 167,434,443 | Nov 12, 2019, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 06, 2019 | Buy | $1.49 | 350,000 | 520,503 | 167,384,443 | Nov 07, 2019, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 31, 2019 | Buy | $1.43 | 50,000 | 71,250 | 167,034,443 | Nov 01, 2019, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 30, 2019 | Buy | $1.44 | 200,000 | 288,533 | 166,984,443 | Oct 31, 2019, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 29, 2019 | Buy | $1.47 | 200,000 | 294,132 | 166,784,443 | Oct 30, 2019, 07:16 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 25, 2019 | Buy | $1.40 | 350,000 | 491,121 | 166,584,443 | Oct 28, 2019, 06:04 AM |
| PFENNIGER RICHARD C JR | Director | Oct 25, 2019 | Buy | $1.45 | 25,000 | 36,242 | 275,000 | Oct 25, 2019, 04:11 PM |
| Rubin Steven D | Executive VP-Administration | Oct 25, 2019 | Buy | $1.50 | 15,000 | 22,500 | 5,744,147 | Oct 25, 2019, 02:46 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 25, 2019 | Buy | $1.50 | 2,000,000 | 3,000,000 | 166,234,443 | Oct 25, 2019, 02:13 PM |
| HSIAO JANE PH D | Vice Chairman & CTO | Oct 25, 2019 | Buy | $1.50 | 400,000 | 600,000 | 5,127,404 | Oct 25, 2019, 02:10 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 16, 2019 | Buy | $2.12 | 50,000 | 105,981 | 30,127,177 | Jul 17, 2019, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 12, 2019 | Buy | $2.16 | 50,000 | 107,788 | 30,077,177 | Jul 15, 2019, 06:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 08, 2019 | Buy | $2.23 | 100,000 | 222,831 | 30,027,177 | Jul 09, 2019, 06:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 02, 2019 | Buy | $2.42 | 50,000 | 120,875 | 29,927,177 | Jul 03, 2019, 01:06 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 25, 2019 | Buy | $2.01 | 100,000 | 200,640 | 29,877,177 | Jun 26, 2019, 06:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 20, 2019 | Buy | $2.04 | 50,000 | 102,127 | 29,777,177 | Jun 21, 2019, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 19, 2019 | Buy | $2.01 | 25,000 | 50,134 | 29,727,177 | Jun 20, 2019, 06:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 18, 2019 | Buy | $2.02 | 50,000 | 100,950 | 29,702,177 | Jun 19, 2019, 06:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 14, 2019 | Buy | $1.91 | 70,000 | 133,864 | 29,652,177 | Jun 17, 2019, 06:46 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 13, 2019 | Buy | $1.92 | 50,000 | 96,200 | 29,582,177 | Jun 14, 2019, 06:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 12, 2019 | Buy | $1.83 | 15,000 | 27,375 | 29,532,177 | Jun 13, 2019, 07:32 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 11, 2019 | Buy | $1.87 | 50,000 | 93,250 | 29,517,177 | Jun 12, 2019, 06:57 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 07, 2019 | Buy | $1.87 | 50,000 | 93,582 | 29,467,177 | Jun 10, 2019, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 06, 2019 | Buy | $1.92 | 25,000 | 47,974 | 29,417,177 | Jun 07, 2019, 07:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 05, 2019 | Buy | $1.92 | 150,000 | 288,201 | 29,392,177 | Jun 06, 2019, 06:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 31, 2019 | Buy | $1.76 | 100,000 | 176,421 | 29,242,177 | Jun 03, 2019, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 30, 2019 | Buy | $1.86 | 50,000 | 93,221 | 29,142,177 | May 31, 2019, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 29, 2019 | Buy | $1.84 | 70,000 | 128,970 | 29,092,177 | May 30, 2019, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 28, 2019 | Buy | $1.90 | 200,000 | 380,342 | 29,022,177 | May 29, 2019, 06:15 AM |
| Fishel Robert Scott | Director | May 28, 2019 | Buy | $1.92 | 50,000 | 96,000 | 4,120,728 | May 29, 2019, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 23, 2019 | Buy | $1.92 | 200,000 | 383,807 | 28,822,177 | May 24, 2019, 06:53 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 22, 2019 | Buy | $2.00 | 125,000 | 250,056 | 28,622,177 | May 23, 2019, 06:04 AM |
| PFENNIGER RICHARD C JR | Director | May 22, 2019 | Buy | $2.05 | 30,000 | 61,500 | 250,000 | May 23, 2019, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 17, 2019 | Buy | $2.08 | 50,000 | 103,931 | 28,497,177 | May 20, 2019, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 16, 2019 | Buy | $2.02 | 100,000 | 202,139 | 28,447,177 | May 17, 2019, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 14, 2019 | Buy | $2.00 | 1,000,000 | 1,995,024 | 28,347,177 | May 15, 2019, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 13, 2019 | Buy | $1.99 | 200,000 | 397,687 | 27,347,177 | May 14, 2019, 06:05 AM |
| PFENNIGER RICHARD C JR | Director | May 13, 2019 | Buy | $2.05 | 50,000 | 102,492 | 220,000 | May 14, 2019, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 10, 2019 | Buy | $2.08 | 70,000 | 145,861 | 27,147,177 | May 13, 2019, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 09, 2019 | Buy | $2.06 | 285,000 | 585,850 | 27,077,177 | May 10, 2019, 06:19 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | May 09, 2019 | Buy | $2.03 | 10,000 | 20,297 | 24,475,147 | May 10, 2019, 06:17 AM |
| Rubin Steven D | Executive VP-Administration | May 09, 2019 | Buy | $2.14 | 10,000 | 21,442 | 5,729,147 | May 10, 2019, 06:16 AM |
| Logal Adam | Sr. Vice President, CFO | May 09, 2019 | Buy | $2.04 | 3,250 | 6,629 | 179,162 | May 10, 2019, 06:13 AM |
| PAGANELLI JOHN A | Director | May 09, 2019 | Buy | $2.09 | 10,000 | 20,888 | 359,340 | May 10, 2019, 06:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 08, 2019 | Buy | $2.11 | 907,000 | 1,914,576 | 26,792,177 | May 09, 2019, 06:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 22, 2019 | Buy | $2.32 | 80,000 | 185,613 | 25,885,177 | Apr 23, 2019, 06:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 17, 2019 | Buy | $2.42 | 50,000 | 120,953 | 25,805,177 | Apr 18, 2019, 07:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 16, 2019 | Buy | $2.50 | 10,000 | 24,997 | 25,755,177 | Apr 17, 2019, 07:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 15, 2019 | Buy | $2.46 | 10,000 | 24,650 | 25,745,177 | Apr 16, 2019, 06:56 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 12, 2019 | Buy | $2.50 | 20,000 | 49,994 | 25,735,177 | Apr 15, 2019, 06:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 11, 2019 | Buy | $2.49 | 30,000 | 74,561 | 25,715,177 | Apr 12, 2019, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 10, 2019 | Buy | $2.53 | 20,000 | 50,602 | 25,685,177 | Apr 11, 2019, 07:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 09, 2019 | Buy | $2.51 | 10,000 | 25,093 | 25,665,177 | Apr 10, 2019, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 04, 2019 | Buy | $2.53 | 20,000 | 50,627 | 25,655,177 | Apr 05, 2019, 07:20 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 02, 2019 | Buy | $2.53 | 40,000 | 101,187 | 25,635,177 | Apr 03, 2019, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 01, 2019 | Buy | $2.58 | 20,000 | 51,560 | 25,595,177 | Apr 02, 2019, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 27, 2019 | Buy | $2.49 | 100,000 | 248,646 | 25,575,177 | Mar 28, 2019, 07:19 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 18, 2019 | Buy | $2.47 | 40,000 | 98,983 | 25,475,177 | Mar 19, 2019, 06:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 14, 2019 | Buy | $2.45 | 250,000 | 612,918 | 25,435,177 | Mar 15, 2019, 09:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 06, 2019 | Buy | $2.57 | 50,000 | 128,622 | 25,185,177 | Mar 07, 2019, 09:45 AM |
| Rubin Steven D | Executive VP-Administration | Mar 06, 2019 | Buy | $2.56 | 8,000 | 20,452 | 5,719,147 | Mar 07, 2019, 09:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 28, 2019 | Buy | $2.48 | 200,000 | 495,947 | 25,135,177 | Mar 01, 2019, 07:38 AM |
| Rubin Steven D | Executive VP-Administration | Feb 01, 2019 | Option Exercise | $3.59 | 5,645 | 20,266 | 5,711,147 | Feb 05, 2019, 04:33 PM |
| Rubin Steven D | Executive VP-Administration | Feb 01, 2019 | Option Exercise | $0.66 | 24,877 | 16,419 | 5,716,792 | Feb 05, 2019, 04:33 PM |
| HSIAO JANE PH D | Vice Chairman & CTO | Jul 30, 2012 | Buy | $4.35 | 30,000 | 130,500 | 4,727,404 | Feb 05, 2019, 04:31 PM |
| HSIAO JANE PH D | Vice Chairman & CTO | Jul 27, 2012 | Buy | $4.30 | 20,000 | 86,000 | 4,697,404 | Feb 05, 2019, 04:31 PM |
| HSIAO JANE PH D | Vice Chairman & CTO | Jan 31, 2014 | Buy | $7.96 | 10,000 | 79,600 | 24,465,147 | Feb 05, 2019, 04:31 PM |
| HSIAO JANE PH D | Vice Chairman & CTO | May 11, 2017 | Buy | $6.92 | 20,000 | 138,500 | 4,677,404 | Feb 05, 2019, 04:30 PM |
| HSIAO JANE PH D | Vice Chairman & CTO | May 10, 2017 | Buy | $6.97 | 40,000 | 278,705 | 4,657,404 | Feb 05, 2019, 04:26 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 17, 2019 | Buy | $3.67 | 15,000 | 55,030 | 24,935,177 | Jan 18, 2019, 06:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 16, 2019 | Buy | $3.74 | 10,000 | 37,369 | 24,920,177 | Jan 17, 2019, 06:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 14, 2019 | Buy | $3.74 | 15,000 | 56,055 | 24,910,177 | Jan 15, 2019, 06:16 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 11, 2019 | Buy | $3.83 | 10,000 | 38,325 | 24,895,177 | Jan 14, 2019, 06:51 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 10, 2019 | Buy | $3.69 | 10,000 | 36,908 | 24,885,177 | Jan 11, 2019, 06:59 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 09, 2019 | Buy | $3.65 | 10,000 | 36,500 | 24,875,177 | Jan 10, 2019, 07:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 08, 2019 | Buy | $3.61 | 35,000 | 126,375 | 24,865,177 | Jan 09, 2019, 07:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 07, 2019 | Buy | $3.56 | 55,000 | 195,922 | 24,830,177 | Jan 08, 2019, 07:32 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 04, 2019 | Buy | $3.43 | 30,000 | 102,914 | 24,775,177 | Jan 07, 2019, 07:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 03, 2019 | Buy | $3.25 | 50,000 | 162,693 | 24,745,177 | Jan 04, 2019, 06:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 02, 2019 | Buy | $3.24 | 40,000 | 129,713 | 24,695,177 | Jan 03, 2019, 07:51 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 31, 2018 | Buy | $2.97 | 135,000 | 401,068 | 24,655,177 | Jan 02, 2019, 08:44 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 28, 2018 | Buy | $3.13 | 100,000 | 312,898 | 24,520,177 | Dec 31, 2018, 07:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 08, 2018 | Option Exercise | $3.49 | 20,057,307 | 70,000,002 | 24,420,177 | Nov 13, 2018, 07:43 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Nov 08, 2018 | Option Exercise | $3.49 | 573,066 | 2,000,000 | 25,346,199 | Nov 13, 2018, 07:42 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 07, 2018 | Buy | $5.57 | 10,000 | 55,705 | 4,362,870 | Sep 10, 2018, 06:30 AM |
| Fishel Robert Scott | Director | Sep 07, 2018 | Buy | $4.63 | 10,000 | 46,300 | 4,070,728 | Sep 10, 2018, 06:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 05, 2018 | Buy | $5.79 | 10,000 | 57,943 | 4,352,870 | Sep 06, 2018, 07:40 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 30, 2018 | Buy | $5.89 | 5,000 | 29,475 | 4,342,870 | Aug 31, 2018, 06:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 28, 2018 | Buy | $5.80 | 5,000 | 28,994 | 4,337,870 | Aug 29, 2018, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 24, 2018 | Buy | $5.70 | 15,000 | 85,553 | 4,332,870 | Aug 27, 2018, 07:25 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 17, 2018 | Buy | $5.54 | 10,000 | 55,358 | 4,317,870 | Aug 20, 2018, 07:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 13, 2018 | Buy | $5.33 | 15,000 | 79,932 | 4,307,870 | Aug 14, 2018, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 09, 2018 | Buy | $5.45 | 10,000 | 54,525 | 4,292,870 | Aug 10, 2018, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 26, 2018 | Buy | $5.06 | 90,000 | 455,206 | 4,282,870 | Jul 27, 2018, 06:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 25, 2018 | Buy | $5.47 | 60,000 | 328,248 | 4,192,870 | Jul 26, 2018, 06:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 24, 2018 | Buy | $5.79 | 10,000 | 57,900 | 4,132,870 | Jul 25, 2018, 06:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 24, 2018 | Buy | $5.55 | 45,000 | 249,869 | 4,122,870 | Jul 25, 2018, 06:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 20, 2018 | Buy | $5.89 | 10,000 | 58,900 | 4,077,870 | Jul 23, 2018, 06:39 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 19, 2018 | Buy | $5.95 | 10,000 | 59,500 | 4,067,870 | Jul 20, 2018, 06:22 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 18, 2018 | Buy | $6.05 | 10,000 | 60,500 | 4,057,870 | Jul 19, 2018, 06:44 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 16, 2018 | Buy | $5.68 | 15,000 | 85,248 | 4,047,870 | Jul 17, 2018, 07:17 AM |
| Fishel Robert Scott | Director | Jul 11, 2018 | Buy | $6.00 | 2,500 | 14,991 | 4,060,728 | Jul 12, 2018, 07:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 03, 2018 | Buy | $4.75 | 10,000 | 47,501 | 4,032,870 | Jul 05, 2018, 07:35 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 29, 2018 | Buy | $4.71 | 7,720 | 36,335 | 4,022,870 | Jul 02, 2018, 06:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 28, 2018 | Buy | $4.68 | 20,000 | 93,600 | 4,015,150 | Jun 29, 2018, 07:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 27, 2018 | Buy | $4.75 | 10,000 | 47,500 | 3,995,150 | Jun 28, 2018, 06:54 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 22, 2018 | Buy | $4.45 | 10,000 | 44,500 | 3,985,150 | Jun 25, 2018, 06:47 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 21, 2018 | Buy | $4.54 | 30,000 | 136,200 | 3,975,150 | Jun 22, 2018, 06:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 19, 2018 | Buy | $4.32 | 20,000 | 86,300 | 3,945,150 | Jun 20, 2018, 06:19 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 18, 2018 | Buy | $4.34 | 14,299 | 62,013 | 3,925,150 | Jun 19, 2018, 06:25 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 15, 2018 | Buy | $4.42 | 10,000 | 44,200 | 3,910,851 | Jun 18, 2018, 06:10 AM |
| Logal Adam | Sr. Vice President, CFO | Jun 08, 2018 | Option Exercise | $4.26 | 63,946 | 272,410 | 175,912 | Jun 12, 2018, 06:05 PM |
| Logal Adam | Sr. Vice President, CFO | Jun 08, 2018 | Option Exercise | $3.43 | 75,000 | 257,250 | 239,858 | Jun 12, 2018, 06:05 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 11, 2018 | Buy | $4.22 | 10,000 | 42,200 | 3,900,851 | Jun 12, 2018, 06:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 07, 2018 | Buy | $4.04 | 10,000 | 40,400 | 3,890,851 | Jun 08, 2018, 07:37 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 06, 2018 | Buy | $4.05 | 30,000 | 121,500 | 3,880,851 | Jun 07, 2018, 07:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 31, 2018 | Buy | $3.76 | 3,900 | 14,664 | 3,850,851 | Jun 01, 2018, 06:49 AM |
| Fishel Robert Scott | Director | May 29, 2018 | Buy | $3.73 | 2,500 | 9,333 | 4,058,228 | May 30, 2018, 07:29 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 25, 2018 | Buy | $3.70 | 10,000 | 37,000 | 3,846,951 | May 29, 2018, 06:31 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 23, 2018 | Buy | $3.73 | 40,000 | 149,300 | 3,836,951 | May 24, 2018, 06:46 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 22, 2018 | Buy | $3.73 | 10,000 | 37,300 | 3,796,951 | May 23, 2018, 07:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 21, 2018 | Buy | $3.82 | 90,000 | 344,096 | 3,786,951 | May 22, 2018, 07:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 18, 2018 | Buy | $4.04 | 100,000 | 403,789 | 3,696,951 | May 21, 2018, 06:24 AM |
| LERNER RICHARD A | Director | May 14, 2018 | Option Exercise | $4.78 | 32,291 | 154,351 | 12,709 | May 15, 2018, 04:13 PM |
| LERNER RICHARD A | Director | May 14, 2018 | Option Exercise | $3.43 | 45,000 | 154,350 | 45,000 | May 15, 2018, 04:13 PM |
| Fishel Robert Scott | Director | May 14, 2018 | Buy | $4.79 | 1,800 | 8,622 | 4,055,728 | May 15, 2018, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 04, 2018 | Buy | $3.14 | 26,000 | 81,540 | 3,596,951 | May 07, 2018, 06:58 AM |
| Fishel Robert Scott | Director | May 04, 2018 | Buy | $3.14 | 5,000 | 15,700 | 4,053,928 | May 07, 2018, 06:57 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 03, 2018 | Buy | $3.09 | 51,800 | 159,998 | 3,570,951 | May 04, 2018, 06:57 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 02, 2018 | Buy | $3.15 | 50,330 | 158,630 | 3,519,151 | May 03, 2018, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 01, 2018 | Buy | $3.05 | 31,222 | 95,210 | 3,468,821 | May 02, 2018, 06:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 30, 2018 | Buy | $3.08 | 75,000 | 231,126 | 3,437,599 | May 01, 2018, 06:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 26, 2018 | Buy | $3.03 | 31,800 | 96,449 | 3,362,599 | Apr 27, 2018, 07:20 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 25, 2018 | Buy | $2.99 | 55,372 | 165,342 | 3,330,799 | Apr 26, 2018, 06:31 AM |
| Fishel Robert Scott | Director | Apr 25, 2018 | Buy | $2.97 | 12,500 | 37,125 | 4,048,928 | Apr 26, 2018, 06:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 24, 2018 | Buy | $2.97 | 75,000 | 222,641 | 3,275,427 | Apr 25, 2018, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 23, 2018 | Buy | $3.04 | 75,000 | 227,655 | 3,200,427 | Apr 24, 2018, 06:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 20, 2018 | Buy | $3.12 | 60,000 | 187,490 | 3,125,427 | Apr 23, 2018, 11:20 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 19, 2018 | Buy | $3.17 | 10,000 | 31,700 | 3,065,427 | Apr 20, 2018, 06:40 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 16, 2018 | Buy | $3.02 | 50,000 | 150,950 | 3,055,427 | Apr 17, 2018, 06:53 AM |
| Fishel Robert Scott | Director | Apr 16, 2018 | Buy | $3.01 | 15,000 | 45,100 | 4,036,428 | Apr 17, 2018, 06:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 13, 2018 | Buy | $2.99 | 30,000 | 89,800 | 3,005,427 | Apr 16, 2018, 06:49 AM |
| Fishel Robert Scott | Director | Apr 13, 2018 | Buy | $3.02 | 10,000 | 30,200 | 4,021,428 | Apr 16, 2018, 06:48 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 12, 2018 | Buy | $3.04 | 65,000 | 197,300 | 2,975,427 | Apr 13, 2018, 06:32 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 11, 2018 | Buy | $3.06 | 43,000 | 131,727 | 2,910,427 | Apr 12, 2018, 06:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 10, 2018 | Buy | $3.06 | 36,527 | 111,706 | 2,867,427 | Apr 11, 2018, 06:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 09, 2018 | Buy | $3.04 | 80,000 | 243,088 | 2,830,900 | Apr 10, 2018, 08:09 AM |
| Fishel Robert Scott | Director | Apr 06, 2018 | Buy | $3.16 | 10,000 | 31,600 | 4,011,428 | Apr 09, 2018, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 06, 2018 | Buy | $3.10 | 60,000 | 186,151 | 2,750,900 | Apr 09, 2018, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 05, 2018 | Buy | $3.25 | 10,000 | 32,500 | 2,690,900 | Apr 06, 2018, 07:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 03, 2018 | Buy | $3.00 | 153,000 | 458,790 | 2,680,900 | Apr 04, 2018, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 28, 2018 | Buy | $3.07 | 80,000 | 245,868 | 2,527,900 | Mar 29, 2018, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 27, 2018 | Buy | $3.25 | 86,100 | 279,689 | 2,447,900 | Mar 28, 2018, 06:19 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 26, 2018 | Buy | $3.19 | 26,000 | 83,055 | 2,361,800 | Mar 27, 2018, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 23, 2018 | Buy | $3.27 | 25,000 | 81,700 | 2,335,800 | Mar 26, 2018, 07:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 22, 2018 | Buy | $3.32 | 30,000 | 99,480 | 2,310,800 | Mar 23, 2018, 06:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 21, 2018 | Buy | $3.38 | 30,000 | 101,384 | 2,280,800 | Mar 22, 2018, 06:47 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 20, 2018 | Buy | $3.32 | 75,000 | 249,365 | 2,250,800 | Mar 21, 2018, 06:34 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 19, 2018 | Buy | $3.51 | 40,000 | 140,240 | 2,175,800 | Mar 20, 2018, 06:21 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 15, 2018 | Buy | $3.32 | 61,000 | 202,524 | 2,135,800 | Mar 16, 2018, 06:54 AM |
| Logal Adam | Sr. Vice President, CFO | Mar 13, 2018 | Buy | $3.40 | 2,065 | 7,011 | 164,858 | Mar 14, 2018, 04:07 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 13, 2018 | Buy | $3.36 | 67,500 | 227,007 | 2,074,800 | Mar 14, 2018, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 12, 2018 | Buy | $3.48 | 25,000 | 86,995 | 2,007,300 | Mar 13, 2018, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 08, 2018 | Buy | $3.28 | 32,000 | 104,835 | 1,982,300 | Mar 09, 2018, 06:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 07, 2018 | Buy | $3.29 | 75,000 | 246,946 | 1,950,300 | Mar 08, 2018, 06:51 AM |
| Rubin Steven D | Executive VP-Administration | Mar 07, 2018 | Buy | $3.25 | 6,000 | 19,500 | 5,691,915 | Mar 08, 2018, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 02, 2018 | Buy | $2.94 | 364,800 | 1,073,716 | 1,875,300 | Mar 05, 2018, 06:29 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 21, 2018 | Buy | $3.63 | 172,500 | 625,955 | 1,510,500 | Feb 22, 2018, 06:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 09, 2018 | Buy | $3.83 | 185,000 | 708,291 | 1,338,000 | Feb 12, 2018, 06:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 08, 2018 | Buy | $4.04 | 20,000 | 80,832 | 1,153,000 | Feb 09, 2018, 06:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 07, 2018 | Buy | $4.22 | 78,000 | 329,251 | 1,133,000 | Feb 08, 2018, 07:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 06, 2018 | Buy | $4.22 | 60,000 | 252,941 | 1,055,000 | Feb 07, 2018, 07:16 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 05, 2018 | Buy | $4.14 | 50,000 | 206,836 | 995,000 | Feb 06, 2018, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 02, 2018 | Buy | $4.30 | 55,000 | 236,680 | 945,000 | Feb 05, 2018, 07:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 31, 2018 | Buy | $4.47 | 65,000 | 290,416 | 890,000 | Feb 01, 2018, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 26, 2018 | Buy | $4.90 | 55,000 | 269,712 | 825,000 | Jan 29, 2018, 06:37 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 25, 2018 | Buy | $4.99 | 75,000 | 374,204 | 770,000 | Jan 26, 2018, 06:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 24, 2018 | Buy | $4.89 | 100,000 | 488,828 | 695,000 | Jan 25, 2018, 07:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 23, 2018 | Buy | $4.76 | 100,000 | 476,070 | 595,000 | Jan 24, 2018, 07:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 22, 2018 | Buy | $4.40 | 100,000 | 439,675 | 495,000 | Jan 23, 2018, 07:39 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 19, 2017 | Buy | $6.01 | 15,000 | 90,099 | 395,000 | Sep 20, 2017, 06:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 18, 2017 | Buy | $6.00 | 40,000 | 240,000 | 380,000 | Sep 19, 2017, 06:26 AM |
| Logal Adam | Sr. Vice President, CFO | Sep 15, 2017 | Buy | $6.03 | 1,500 | 9,045 | 162,793 | Sep 18, 2017, 06:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 15, 2017 | Buy | $6.01 | 80,000 | 480,411 | 340,000 | Sep 18, 2017, 06:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 14, 2017 | Buy | $5.98 | 260,000 | 1,555,624 | 260,000 | Sep 15, 2017, 08:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 25, 2017 | Buy | $6.17 | 25,000 | 154,236 | 164,234,443 | Aug 28, 2017, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 24, 2017 | Buy | $6.24 | 10,000 | 62,353 | 164,209,443 | Aug 25, 2017, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 23, 2017 | Buy | $6.13 | 12,000 | 73,554 | 164,199,443 | Aug 24, 2017, 07:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 22, 2017 | Buy | $6.13 | 1,800 | 11,034 | 164,187,443 | Aug 23, 2017, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 21, 2017 | Buy | $6.10 | 25,000 | 152,539 | 164,185,643 | Aug 22, 2017, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 17, 2017 | Buy | $5.96 | 50,000 | 298,048 | 164,160,643 | Aug 18, 2017, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 16, 2017 | Buy | $6.04 | 40,000 | 241,734 | 164,110,643 | Aug 17, 2017, 07:19 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 15, 2017 | Buy | $6.08 | 25,000 | 152,074 | 164,070,643 | Aug 16, 2017, 07:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 14, 2017 | Buy | $6.15 | 10,000 | 61,527 | 164,045,643 | Aug 15, 2017, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 11, 2017 | Buy | $6.19 | 10,000 | 61,895 | 164,035,643 | Aug 14, 2017, 06:53 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 10, 2017 | Buy | $6.23 | 39,000 | 242,794 | 164,025,643 | Aug 11, 2017, 07:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 09, 2017 | Buy | $6.35 | 18,000 | 114,227 | 163,986,643 | Aug 10, 2017, 06:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 08, 2017 | Buy | $6.05 | 5,000 | 30,250 | 163,968,643 | Aug 09, 2017, 06:54 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 02, 2017 | Buy | $6.15 | 25,000 | 153,740 | 163,963,643 | Aug 03, 2017, 07:25 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 01, 2017 | Buy | $6.25 | 46,600 | 291,046 | 163,938,643 | Aug 02, 2017, 07:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 28, 2017 | Buy | $6.30 | 35,100 | 221,012 | 163,892,043 | Jul 31, 2017, 06:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 27, 2017 | Buy | $6.34 | 23,600 | 149,687 | 163,856,943 | Jul 28, 2017, 06:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 26, 2017 | Buy | $6.39 | 36,200 | 231,214 | 163,833,343 | Jul 27, 2017, 06:21 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 25, 2017 | Buy | $6.41 | 39,800 | 255,170 | 163,797,143 | Jul 26, 2017, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 24, 2017 | Buy | $6.42 | 45,000 | 289,049 | 163,757,343 | Jul 25, 2017, 06:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 20, 2017 | Buy | $6.46 | 5,400 | 34,871 | 163,712,343 | Jul 21, 2017, 06:47 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 17, 2017 | Buy | $6.04 | 1,800 | 10,871 | 163,706,943 | Jul 18, 2017, 07:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 14, 2017 | Buy | $6.16 | 12,600 | 77,563 | 163,705,143 | Jul 17, 2017, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 12, 2017 | Buy | $6.12 | 3,600 | 22,049 | 163,692,543 | Jul 13, 2017, 06:57 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 10, 2017 | Buy | $6.19 | 50,000 | 309,570 | 163,688,943 | Jul 11, 2017, 06:38 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 06, 2017 | Buy | $6.29 | 25,000 | 157,141 | 163,638,943 | Jul 07, 2017, 06:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 03, 2017 | Buy | $6.44 | 60,800 | 391,396 | 163,613,943 | Jul 05, 2017, 06:46 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 30, 2017 | Buy | $6.58 | 3,600 | 23,699 | 163,553,143 | Jul 03, 2017, 08:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 28, 2017 | Buy | $6.87 | 1,800 | 12,366 | 163,549,543 | Jun 29, 2017, 06:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 27, 2017 | Buy | $6.77 | 21,800 | 147,540 | 163,547,743 | Jun 28, 2017, 07:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 26, 2017 | Buy | $6.97 | 1,800 | 12,543 | 163,525,943 | Jun 27, 2017, 07:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 22, 2017 | Buy | $6.72 | 131,000 | 880,268 | 163,524,143 | Jun 23, 2017, 06:31 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 15, 2017 | Buy | $6.43 | 200,000 | 1,285,692 | 163,393,143 | Jun 16, 2017, 06:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 13, 2017 | Buy | $6.51 | 7,200 | 46,901 | 163,193,143 | Jun 14, 2017, 06:33 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 12, 2017 | Buy | $6.37 | 1,800 | 11,458 | 163,185,943 | Jun 13, 2017, 06:22 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 09, 2017 | Buy | $6.39 | 25,000 | 159,643 | 163,184,143 | Jun 12, 2017, 06:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 07, 2017 | Buy | $6.27 | 55,600 | 348,785 | 163,159,143 | Jun 08, 2017, 07:39 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 06, 2017 | Buy | $6.30 | 30,000 | 189,147 | 163,103,543 | Jun 07, 2017, 07:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 05, 2017 | Buy | $6.31 | 55,000 | 347,135 | 163,073,543 | Jun 06, 2017, 07:17 AM |
| LERNER RICHARD A | Director | Jun 05, 2017 | Buy | $6.31 | 10,000 | 63,135 | 166,172 | Jun 06, 2017, 07:16 AM |
| PFENNIGER RICHARD C JR | Director | Jun 02, 2017 | Option Exercise | $3.43 | 20,000 | 68,600 | 170,000 | Jun 05, 2017, 09:49 AM |
| PAGANELLI JOHN A | Director | Jun 01, 2017 | Buy | $6.17 | 5,000 | 30,840 | 9,175 | Jun 02, 2017, 11:36 AM |
| Rubin Steven D | Executive VP-Administration | May 31, 2017 | Buy | $6.10 | 2,000 | 12,200 | 5,685,915 | Jun 01, 2017, 09:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 31, 2017 | Buy | $6.11 | 207,700 | 1,269,461 | 163,018,543 | Jun 01, 2017, 06:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 30, 2017 | Buy | $6.28 | 18,600 | 116,773 | 162,810,843 | May 31, 2017, 06:48 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 26, 2017 | Buy | $6.31 | 64,600 | 407,432 | 162,792,243 | May 30, 2017, 07:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 25, 2017 | Buy | $6.38 | 26,000 | 165,786 | 162,727,643 | May 26, 2017, 07:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 24, 2017 | Buy | $6.42 | 42,200 | 270,959 | 162,701,643 | May 25, 2017, 06:20 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 22, 2017 | Buy | $6.43 | 120,000 | 772,174 | 162,659,443 | May 23, 2017, 07:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 19, 2017 | Buy | $6.60 | 9,200 | 60,685 | 162,539,443 | May 22, 2017, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 18, 2017 | Buy | $6.59 | 20,000 | 131,807 | 162,530,243 | May 19, 2017, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 17, 2017 | Buy | $6.54 | 70,800 | 463,256 | 162,510,243 | May 18, 2017, 07:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 16, 2017 | Buy | $6.61 | 27,800 | 183,634 | 162,439,443 | May 17, 2017, 06:45 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | May 11, 2017 | Buy | $6.92 | 20,000 | 138,500 | 24,773,133 | May 12, 2017, 10:53 AM |
| Rubin Steven D | Executive VP-Administration | May 11, 2017 | Buy | $6.91 | 2,000 | 13,814 | 5,683,915 | May 11, 2017, 02:17 PM |
| HSIAO JANE PH D | Vice Chairman & CTO | May 10, 2017 | Buy | $6.97 | 40,000 | 278,705 | 24,753,133 | May 11, 2017, 06:50 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 10, 2017 | Buy | $6.96 | 1,125,000 | 7,829,775 | 162,411,643 | May 11, 2017, 06:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 08, 2017 | Buy | $7.22 | 100,000 | 722,248 | 161,286,643 | May 09, 2017, 06:46 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 05, 2017 | Buy | $7.52 | 10,000 | 75,234 | 161,186,643 | May 08, 2017, 06:54 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 04, 2017 | Buy | $7.51 | 11,800 | 88,592 | 161,176,643 | May 05, 2017, 06:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 03, 2017 | Buy | $7.53 | 11,000 | 82,784 | 161,164,843 | May 04, 2017, 06:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 02, 2017 | Buy | $7.58 | 15,000 | 113,760 | 161,153,843 | May 02, 2017, 06:56 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 01, 2017 | Buy | $7.68 | 4,700 | 36,104 | 161,138,843 | May 02, 2017, 07:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 28, 2017 | Buy | $7.78 | 9,000 | 70,010 | 161,134,143 | May 01, 2017, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 27, 2017 | Buy | $7.81 | 22,500 | 175,787 | 161,125,143 | Apr 28, 2017, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 26, 2017 | Buy | $7.84 | 5,000 | 39,196 | 161,102,643 | Apr 27, 2017, 07:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 21, 2017 | Buy | $7.48 | 19,000 | 142,196 | 161,097,643 | Apr 24, 2017, 07:32 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 19, 2017 | Buy | $7.49 | 15,000 | 112,290 | 161,078,643 | Apr 20, 2017, 07:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 18, 2017 | Buy | $7.26 | 27,800 | 201,790 | 161,063,643 | Apr 19, 2017, 07:32 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 17, 2017 | Buy | $7.48 | 13,600 | 101,676 | 161,035,843 | Apr 18, 2017, 07:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 13, 2017 | Buy | $7.58 | 30,800 | 233,400 | 161,022,243 | Apr 14, 2017, 07:45 AM |
| Rubin Steven D | Executive VP-Administration | Apr 12, 2017 | Option Exercise | $7.66 | 158,336 | 1,212,854 | 5,681,915 | Apr 13, 2017, 04:25 PM |
| Rubin Steven D | Executive VP-Administration | Apr 12, 2017 | Option Exercise | $2.36 | 265,000 | 625,400 | 5,840,251 | Apr 13, 2017, 04:25 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 11, 2017 | Buy | $7.49 | 18,000 | 134,909 | 160,991,443 | Apr 12, 2017, 06:12 AM |
| Yu Alice Lin-Tsing | Director | Apr 10, 2017 | Option Exercise | $4.72 | 20,000 | 94,400 | 100,000 | Apr 11, 2017, 04:14 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 10, 2017 | Buy | $7.60 | 33,000 | 250,842 | 160,973,443 | Apr 11, 2017, 07:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 07, 2017 | Buy | $7.58 | 28,000 | 212,220 | 160,940,443 | Apr 10, 2017, 08:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 06, 2017 | Buy | $7.58 | 28,600 | 216,881 | 160,912,443 | Apr 07, 2017, 08:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 05, 2017 | Buy | $7.69 | 44,500 | 342,042 | 160,883,843 | Apr 06, 2017, 07:31 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 04, 2017 | Buy | $7.69 | 7,400 | 56,943 | 160,839,343 | Apr 05, 2017, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 03, 2017 | Buy | $7.82 | 21,600 | 168,908 | 160,831,943 | Apr 04, 2017, 07:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 31, 2017 | Buy | $8.00 | 1,800 | 14,400 | 160,810,343 | Apr 03, 2017, 07:34 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 30, 2017 | Buy | $8.02 | 10,600 | 85,043 | 160,808,543 | Mar 31, 2017, 07:40 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 29, 2017 | Buy | $8.14 | 9,200 | 74,847 | 160,797,943 | Mar 30, 2017, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 28, 2017 | Buy | $8.03 | 3,600 | 28,895 | 160,788,743 | Mar 29, 2017, 08:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 24, 2017 | Buy | $7.75 | 3,600 | 27,916 | 160,785,143 | Mar 27, 2017, 06:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 23, 2017 | Buy | $7.71 | 12,200 | 94,023 | 160,781,543 | Mar 24, 2017, 07:25 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 21, 2017 | Buy | $7.85 | 5,800 | 45,531 | 160,769,343 | Mar 22, 2017, 07:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 20, 2017 | Buy | $7.99 | 11,000 | 87,924 | 160,763,543 | Mar 21, 2017, 07:32 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 17, 2017 | Buy | $8.19 | 9,000 | 73,710 | 160,752,543 | Mar 20, 2017, 07:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 15, 2017 | Buy | $8.03 | 1,800 | 14,453 | 160,743,543 | Mar 16, 2017, 07:10 AM |
| Logal Adam | Sr. Vice President, CFO | Mar 13, 2017 | Option Exercise | $7.92 | 35,728 | 282,966 | 274,268 | Mar 15, 2017, 06:31 PM |
| Logal Adam | Sr. Vice President, CFO | Mar 13, 2017 | Option Exercise | $1.07 | 264,207 | 282,956 | 309,996 | Mar 15, 2017, 06:31 PM |
| Logal Adam | Sr. Vice President, CFO | Mar 14, 2017 | Sale | $8.07 | 112,975 | 911,674 | 161,293 | Mar 15, 2017, 06:31 PM |
| LERNER RICHARD A | Director | Mar 13, 2017 | Option Exercise | $7.92 | 5,177 | 41,002 | 44,823 | Mar 15, 2017, 06:30 PM |
| LERNER RICHARD A | Director | Mar 13, 2017 | Option Exercise | $2.05 | 20,000 | 41,000 | 50,000 | Mar 15, 2017, 06:30 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 10, 2017 | Buy | $7.97 | 1,800 | 14,345 | 160,741,743 | Mar 13, 2017, 07:22 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 09, 2017 | Buy | $7.84 | 3,600 | 28,209 | 160,739,943 | Mar 10, 2017, 07:22 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 08, 2017 | Buy | $7.92 | 1,800 | 14,256 | 160,736,343 | Mar 09, 2017, 07:07 AM |
| PAGANELLI JOHN A | Director | Mar 06, 2017 | Option Exercise | $7.61 | 9,015 | 68,604 | 350,340 | Mar 07, 2017, 05:08 PM |
| PAGANELLI JOHN A | Director | Mar 06, 2017 | Option Exercise | $3.43 | 20,000 | 68,600 | 359,355 | Mar 07, 2017, 05:08 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 03, 2017 | Buy | $7.43 | 8,600 | 63,894 | 160,734,543 | Mar 06, 2017, 07:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 02, 2017 | Buy | $7.53 | 94,800 | 713,787 | 160,725,943 | Mar 03, 2017, 08:05 AM |
| PAGANELLI JOHN A | Director | Feb 22, 2017 | Option Exercise | $8.45 | 4,853 | 41,008 | 339,355 | Feb 28, 2017, 06:27 PM |
| PAGANELLI JOHN A | Director | Feb 22, 2017 | Option Exercise | $2.05 | 20,000 | 41,000 | 344,208 | Feb 28, 2017, 06:27 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 24, 2017 | Buy | $8.45 | 3,600 | 30,436 | 160,631,143 | Feb 27, 2017, 07:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 23, 2017 | Buy | $8.39 | 1,800 | 15,102 | 160,627,543 | Feb 24, 2017, 06:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 22, 2017 | Buy | $8.54 | 1,800 | 15,371 | 160,625,743 | Feb 23, 2017, 07:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 21, 2017 | Buy | $8.80 | 3,600 | 31,680 | 160,623,943 | Feb 22, 2017, 07:21 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 17, 2017 | Buy | $8.80 | 1,800 | 15,836 | 160,620,343 | Feb 21, 2017, 06:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 16, 2017 | Buy | $8.65 | 1,800 | 15,570 | 160,618,543 | Feb 17, 2017, 07:33 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 15, 2017 | Buy | $8.46 | 1,800 | 15,228 | 160,616,743 | Feb 16, 2017, 06:25 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 14, 2017 | Buy | $8.41 | 1,800 | 15,138 | 160,614,943 | Feb 15, 2017, 07:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 13, 2017 | Buy | $8.36 | 1,800 | 15,046 | 160,613,143 | Feb 14, 2017, 07:20 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 10, 2017 | Buy | $8.14 | 1,800 | 14,656 | 160,611,343 | Feb 13, 2017, 07:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 09, 2017 | Buy | $8.07 | 10,000 | 80,696 | 160,609,543 | Feb 10, 2017, 07:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 08, 2017 | Buy | $8.13 | 15,600 | 126,891 | 160,599,543 | Feb 09, 2017, 07:49 AM |
| Rubin Steven D | Executive VP-Administration | Feb 08, 2017 | Buy | $8.11 | 2,000 | 16,214 | 5,575,251 | Feb 09, 2017, 07:46 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 07, 2017 | Buy | $8.27 | 5,400 | 44,671 | 160,583,943 | Feb 08, 2017, 07:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 06, 2017 | Buy | $8.32 | 20,600 | 171,435 | 160,578,543 | Feb 07, 2017, 10:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 02, 2017 | Buy | $8.53 | 6,000 | 51,156 | 160,557,943 | Feb 03, 2017, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 01, 2017 | Buy | $8.59 | 9,000 | 77,341 | 160,551,943 | Feb 02, 2017, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 31, 2017 | Buy | $8.60 | 12,000 | 103,179 | 160,542,943 | Feb 01, 2017, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 30, 2017 | Buy | $8.49 | 10,000 | 84,860 | 160,530,943 | Jan 31, 2017, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 27, 2017 | Buy | $8.67 | 12,000 | 103,984 | 160,520,943 | Jan 30, 2017, 07:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 25, 2017 | Buy | $8.55 | 10,000 | 85,507 | 160,508,943 | Jan 26, 2017, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 24, 2017 | Buy | $8.46 | 10,000 | 84,572 | 160,498,943 | Jan 25, 2017, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 23, 2017 | Buy | $8.48 | 12,000 | 101,778 | 160,488,943 | Jan 24, 2017, 06:35 AM |
| BARON ROBERT A | Director | Jan 19, 2017 | Option Exercise | $8.75 | 23,315 | 204,006 | 320,773 | Jan 23, 2017, 07:30 AM |
| BARON ROBERT A | Director | Jan 19, 2017 | Option Exercise | $3.40 | 60,000 | 204,000 | 344,088 | Jan 23, 2017, 07:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 20, 2017 | Buy | $8.72 | 8,600 | 74,977 | 160,476,943 | Jan 23, 2017, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 19, 2017 | Buy | $8.75 | 20,000 | 175,038 | 160,468,343 | Jan 20, 2017, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 18, 2017 | Buy | $8.87 | 10,700 | 94,860 | 160,448,343 | Jan 19, 2017, 06:03 AM |
| BEIER THOMAS E | Director | Jan 13, 2017 | Option Exercise | $2.05 | 20,000 | 41,000 | 60,000 | Jan 17, 2017, 04:12 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 13, 2017 | Buy | $9.15 | 15,000 | 137,225 | 160,437,643 | Jan 17, 2017, 06:09 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Jan 04, 2017 | Option Exercise | $7.61 | 112,500 | 856,125 | 24,713,133 | Jan 05, 2017, 11:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 03, 2017 | Buy | $9.04 | 20,000 | 180,794 | 160,422,643 | Jan 04, 2017, 06:02 AM |
| Rubin Steven D | Executive VP-Administration | Dec 30, 2016 | Buy | $9.18 | 2,000 | 18,353 | 5,573,251 | Jan 03, 2017, 07:56 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 30, 2016 | Buy | $9.42 | 25,000 | 235,515 | 160,402,643 | Jan 03, 2017, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 02, 2016 | Buy | $10.49 | 1,000 | 10,488 | 160,377,643 | Dec 05, 2016, 06:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 01, 2016 | Buy | $10.27 | 3,800 | 39,035 | 160,376,643 | Dec 02, 2016, 07:46 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 30, 2016 | Buy | $10.40 | 1,800 | 18,720 | 160,372,843 | Dec 01, 2016, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 28, 2016 | Buy | $10.61 | 5,600 | 59,411 | 160,371,043 | Nov 29, 2016, 07:37 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 23, 2016 | Buy | $10.09 | 4,300 | 43,387 | 160,365,443 | Nov 25, 2016, 07:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 22, 2016 | Buy | $10.28 | 5,400 | 55,523 | 160,361,143 | Nov 23, 2016, 07:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 21, 2016 | Buy | $10.41 | 3,600 | 37,468 | 160,355,743 | Nov 22, 2016, 06:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 18, 2016 | Buy | $10.38 | 1,800 | 18,692 | 160,352,143 | Nov 21, 2016, 07:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 16, 2016 | Buy | $10.13 | 4,300 | 43,565 | 160,350,343 | Nov 17, 2016, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 11, 2016 | Buy | $9.24 | 1,800 | 16,632 | 160,346,043 | Nov 14, 2016, 06:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 10, 2016 | Buy | $9.49 | 12,800 | 121,511 | 160,344,243 | Nov 14, 2016, 06:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 09, 2016 | Buy | $9.33 | 5,400 | 50,382 | 160,331,443 | Nov 10, 2016, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 08, 2016 | Buy | $9.22 | 23,100 | 213,054 | 160,326,043 | Nov 09, 2016, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 02, 2016 | Buy | $9.48 | 10,000 | 94,845 | 160,302,943 | Nov 03, 2016, 06:19 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 01, 2016 | Buy | $9.49 | 10,000 | 94,878 | 160,292,943 | Nov 02, 2016, 06:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 31, 2016 | Buy | $9.43 | 11,800 | 111,279 | 160,282,943 | Nov 01, 2016, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 28, 2016 | Buy | $9.46 | 10,000 | 94,566 | 160,271,143 | Oct 31, 2016, 06:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 27, 2016 | Buy | $9.36 | 10,000 | 93,568 | 160,261,143 | Oct 28, 2016, 06:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 26, 2016 | Buy | $9.27 | 5,600 | 51,939 | 160,251,143 | Oct 27, 2016, 07:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 25, 2016 | Buy | $9.38 | 3,600 | 33,750 | 160,245,543 | Oct 26, 2016, 07:57 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 24, 2016 | Buy | $9.49 | 1,800 | 17,091 | 160,241,943 | Oct 25, 2016, 06:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 21, 2016 | Buy | $9.38 | 1,800 | 16,884 | 160,240,143 | Oct 24, 2016, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 20, 2016 | Buy | $9.26 | 2,700 | 24,989 | 160,238,343 | Oct 21, 2016, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 19, 2016 | Buy | $9.26 | 14,700 | 136,131 | 160,235,643 | Oct 20, 2016, 07:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 18, 2016 | Buy | $9.29 | 1,800 | 16,722 | 160,220,943 | Oct 19, 2016, 07:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 17, 2016 | Buy | $9.34 | 3,600 | 33,641 | 160,219,143 | Oct 18, 2016, 06:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 14, 2016 | Buy | $9.48 | 1,800 | 17,064 | 160,215,543 | Oct 17, 2016, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 13, 2016 | Buy | $9.52 | 5,400 | 51,432 | 160,213,743 | Oct 14, 2016, 06:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 11, 2016 | Buy | $9.78 | 7,200 | 70,431 | 160,208,343 | Oct 12, 2016, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 10, 2016 | Buy | $9.91 | 7,200 | 71,319 | 160,201,143 | Oct 11, 2016, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 07, 2016 | Buy | $9.79 | 17,600 | 172,277 | 160,193,943 | Oct 11, 2016, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 06, 2016 | Buy | $10.53 | 4,200 | 44,242 | 160,176,343 | Oct 07, 2016, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 04, 2016 | Buy | $10.57 | 3,600 | 38,056 | 160,172,143 | Oct 05, 2016, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 30, 2016 | Buy | $10.54 | 1,800 | 18,971 | 160,168,543 | Oct 03, 2016, 06:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 29, 2016 | Buy | $10.67 | 3,600 | 38,418 | 160,166,743 | Sep 30, 2016, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 28, 2016 | Buy | $11.01 | 5,400 | 59,448 | 160,163,143 | Sep 29, 2016, 06:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 27, 2016 | Buy | $11.16 | 1,800 | 20,086 | 160,157,743 | Sep 28, 2016, 06:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 26, 2016 | Buy | $11.04 | 1,800 | 19,880 | 160,155,943 | Sep 27, 2016, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 23, 2016 | Buy | $10.95 | 1,800 | 19,709 | 160,154,143 | Sep 26, 2016, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 22, 2016 | Buy | $10.63 | 1,800 | 19,131 | 160,152,343 | Sep 23, 2016, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 21, 2016 | Buy | $10.46 | 1,800 | 18,828 | 160,150,543 | Sep 22, 2016, 07:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 20, 2016 | Buy | $10.36 | 1,800 | 18,648 | 160,148,743 | Sep 21, 2016, 06:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 19, 2016 | Buy | $10.18 | 1,800 | 18,324 | 160,146,943 | Sep 20, 2016, 06:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 13, 2016 | Buy | $9.95 | 10,000 | 99,530 | 160,145,143 | Sep 14, 2016, 06:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 12, 2016 | Buy | $9.79 | 10,000 | 97,869 | 160,135,143 | Sep 13, 2016, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 09, 2016 | Buy | $9.87 | 3,600 | 35,535 | 160,125,143 | Sep 12, 2016, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 02, 2016 | Buy | $9.28 | 10,000 | 92,800 | 160,121,543 | Sep 06, 2016, 11:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 25, 2016 | Buy | $9.06 | 48,400 | 438,293 | 160,111,543 | Aug 26, 2016, 06:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 24, 2016 | Buy | $9.24 | 15,000 | 138,586 | 160,063,143 | Aug 25, 2016, 06:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 23, 2016 | Buy | $9.53 | 29,000 | 276,464 | 160,048,143 | Aug 24, 2016, 07:31 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 22, 2016 | Buy | $9.76 | 11,800 | 115,214 | 160,019,143 | Aug 23, 2016, 07:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 19, 2016 | Buy | $9.82 | 15,000 | 147,236 | 160,007,343 | Aug 22, 2016, 07:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 18, 2016 | Buy | $9.87 | 10,000 | 98,717 | 159,992,343 | Aug 19, 2016, 07:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 17, 2016 | Buy | $9.90 | 10,000 | 98,953 | 159,982,343 | Aug 18, 2016, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 16, 2016 | Buy | $10.02 | 10,000 | 100,183 | 159,972,343 | Aug 17, 2016, 06:29 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 15, 2016 | Buy | $10.07 | 10,000 | 100,665 | 159,962,343 | Aug 16, 2016, 06:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 10, 2016 | Buy | $9.98 | 10,000 | 99,763 | 159,952,343 | Aug 11, 2016, 06:29 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 09, 2016 | Buy | $10.21 | 10,000 | 102,140 | 159,942,343 | Aug 10, 2016, 06:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 02, 2016 | Buy | $9.88 | 10,000 | 98,802 | 159,932,343 | Aug 03, 2016, 07:21 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 27, 2016 | Buy | $9.91 | 10,000 | 99,142 | 159,922,343 | Jul 28, 2016, 06:22 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 13, 2016 | Buy | $9.65 | 15,800 | 152,453 | 159,912,343 | Jul 14, 2016, 06:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 11, 2016 | Buy | $9.82 | 10,000 | 98,182 | 159,896,543 | Jul 12, 2016, 06:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 30, 2016 | Buy | $9.27 | 18,000 | 166,844 | 159,886,543 | Jul 01, 2016, 10:34 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 29, 2016 | Buy | $9.24 | 12,800 | 118,303 | 159,868,543 | Jun 30, 2016, 07:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 27, 2016 | Buy | $8.88 | 21,000 | 186,383 | 159,855,743 | Jun 28, 2016, 06:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 24, 2016 | Buy | $9.40 | 18,000 | 169,245 | 159,834,743 | Jun 27, 2016, 06:46 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 22, 2016 | Buy | $9.42 | 18,000 | 169,581 | 159,816,743 | Jun 23, 2016, 06:31 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 20, 2016 | Buy | $9.19 | 10,000 | 91,892 | 159,798,743 | Jun 21, 2016, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 17, 2016 | Buy | $9.07 | 18,000 | 163,231 | 159,788,743 | Jun 20, 2016, 06:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 16, 2016 | Buy | $9.23 | 10,000 | 92,335 | 159,770,743 | Jun 17, 2016, 06:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 14, 2016 | Buy | $9.01 | 16,000 | 144,177 | 159,760,743 | Jun 15, 2016, 06:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 10, 2016 | Buy | $9.36 | 10,000 | 93,579 | 159,744,743 | Jun 13, 2016, 07:31 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 09, 2016 | Buy | $9.74 | 5,000 | 48,677 | 159,734,743 | Jun 10, 2016, 06:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 08, 2016 | Buy | $9.80 | 11,200 | 109,752 | 159,729,743 | Jun 09, 2016, 06:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 07, 2016 | Buy | $9.90 | 5,000 | 49,498 | 159,718,543 | Jun 08, 2016, 06:53 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 06, 2016 | Buy | $9.97 | 17,800 | 177,385 | 159,713,543 | Jun 07, 2016, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 03, 2016 | Buy | $10.07 | 18,600 | 187,362 | 159,695,743 | Jun 06, 2016, 06:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 01, 2016 | Buy | $10.49 | 10,800 | 113,262 | 159,677,143 | Jun 02, 2016, 06:37 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 27, 2016 | Buy | $10.35 | 20,000 | 207,014 | 159,666,343 | May 31, 2016, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 26, 2016 | Buy | $10.45 | 12,000 | 125,436 | 159,646,343 | May 27, 2016, 06:00 AM |
| Rubin Steven D | Executive VP-Administration | May 03, 2016 | Option Exercise | $10.34 | 121,156 | 1,252,753 | 5,571,251 | May 17, 2016, 05:08 PM |
| BARON ROBERT A | Director | May 13, 2016 | Sale | $9.83 | 37,500 | 368,491 | 297,604 | May 17, 2016, 04:22 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 12, 2016 | Buy | $9.56 | 30,600 | 292,656 | 159,634,343 | May 13, 2016, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 11, 2016 | Buy | $10.05 | 19,400 | 194,980 | 159,603,743 | May 12, 2016, 07:06 AM |
| Rubin Steven D | Executive VP-Administration | May 03, 2016 | Option Exercise | $10.34 | 134,918 | 1,395,052 | 5,557,489 | May 05, 2016, 05:20 PM |
| Rubin Steven D | Executive VP-Administration | May 03, 2016 | Option Exercise | $1.16 | 250,000 | 290,000 | 5,692,407 | May 05, 2016, 05:20 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 04, 2016 | Buy | $9.91 | 29,800 | 295,333 | 159,584,343 | May 05, 2016, 06:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 03, 2016 | Buy | $10.25 | 8,100 | 83,017 | 159,554,543 | May 04, 2016, 06:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 02, 2016 | Buy | $10.33 | 11,800 | 121,926 | 159,546,443 | May 03, 2016, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 29, 2016 | Buy | $10.70 | 10,000 | 107,049 | 159,534,643 | May 02, 2016, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 28, 2016 | Buy | $10.83 | 10,000 | 108,325 | 159,524,643 | Apr 29, 2016, 06:31 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 27, 2016 | Buy | $10.95 | 11,800 | 129,157 | 159,514,643 | Apr 28, 2016, 07:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 25, 2016 | Buy | $11.12 | 15,000 | 166,735 | 159,502,843 | Apr 26, 2016, 06:50 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 19, 2016 | Buy | $11.00 | 7,400 | 81,373 | 159,487,843 | Apr 20, 2016, 06:50 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 15, 2016 | Buy | $10.78 | 7,600 | 81,926 | 159,480,443 | Apr 18, 2016, 06:44 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 06, 2016 | Buy | $10.61 | 20,000 | 212,157 | 159,472,843 | Apr 07, 2016, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 05, 2016 | Buy | $10.28 | 20,000 | 205,646 | 159,452,843 | Apr 06, 2016, 07:21 AM |
| BEIER THOMAS E | Director | Apr 01, 2016 | Option Exercise | $1.54 | 20,000 | 30,800 | 40,000 | Apr 05, 2016, 04:39 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 01, 2016 | Buy | $10.35 | 23,600 | 244,254 | 159,432,843 | Apr 01, 2016, 05:55 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 31, 2016 | Buy | $10.26 | 25,000 | 256,498 | 159,409,243 | Apr 01, 2016, 08:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 30, 2016 | Buy | $10.10 | 85,600 | 864,320 | 159,384,243 | Mar 31, 2016, 06:05 AM |
| Rubin Steven D | Executive VP-Administration | Mar 30, 2016 | Buy | $10.17 | 1,000 | 10,166 | 5,442,407 | Mar 31, 2016, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 24, 2016 | Buy | $11.14 | 20,000 | 222,787 | 159,298,643 | Mar 25, 2016, 08:42 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Mar 17, 2016 | Buy | $10.65 | 1,200 | 12,785 | 24,600,633 | Mar 18, 2016, 07:31 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Mar 16, 2016 | Buy | $9.99 | 1,200 | 11,988 | 24,599,433 | Mar 17, 2016, 04:19 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 15, 2016 | Buy | $9.96 | 30,000 | 298,762 | 159,278,643 | Mar 16, 2016, 06:06 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Mar 15, 2016 | Buy | $10.00 | 1,200 | 12,000 | 24,598,233 | Mar 16, 2016, 06:06 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Mar 14, 2016 | Buy | $10.12 | 1,200 | 12,143 | 24,597,033 | Mar 16, 2016, 06:06 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Mar 11, 2016 | Buy | $10.21 | 1,200 | 12,252 | 24,595,833 | Mar 15, 2016, 04:22 PM |
| HSIAO JANE PH D | Vice Chairman & CTO | Mar 10, 2016 | Buy | $9.82 | 1,200 | 11,787 | 24,594,633 | Mar 15, 2016, 04:20 PM |
| HSIAO JANE PH D | Vice Chairman & CTO | Mar 09, 2016 | Buy | $9.99 | 1,200 | 11,988 | 24,593,433 | Mar 15, 2016, 04:20 PM |
| HSIAO JANE PH D | Vice Chairman & CTO | Mar 08, 2016 | Buy | $10.01 | 1,200 | 12,012 | 24,592,233 | Mar 15, 2016, 04:20 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 10, 2016 | Buy | $9.89 | 23,600 | 233,396 | 159,248,643 | Mar 11, 2016, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 08, 2016 | Buy | $10.00 | 5,400 | 53,997 | 159,225,043 | Mar 09, 2016, 06:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 04, 2016 | Buy | $9.66 | 11,900 | 114,906 | 159,219,643 | Mar 07, 2016, 06:46 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 03, 2016 | Buy | $9.61 | 7,200 | 69,198 | 159,207,743 | Mar 04, 2016, 07:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 01, 2016 | Buy | $9.08 | 64,800 | 588,125 | 159,200,543 | Mar 02, 2016, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 26, 2016 | Buy | $9.27 | 4,800 | 44,507 | 159,135,743 | Feb 29, 2016, 07:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 24, 2016 | Buy | $8.70 | 7,200 | 62,607 | 159,130,943 | Feb 25, 2016, 06:51 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 23, 2016 | Buy | $8.92 | 27,800 | 248,096 | 159,123,743 | Feb 24, 2016, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 18, 2016 | Buy | $8.74 | 13,000 | 113,652 | 159,095,943 | Feb 19, 2016, 07:21 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 17, 2016 | Buy | $8.01 | 2,000 | 16,029 | 159,082,943 | Feb 18, 2016, 06:54 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 16, 2016 | Buy | $7.92 | 15,000 | 118,730 | 159,080,943 | Feb 17, 2016, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 12, 2016 | Buy | $7.88 | 11,000 | 86,705 | 159,065,943 | Feb 16, 2016, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 11, 2016 | Buy | $7.92 | 21,800 | 172,671 | 159,054,943 | Feb 12, 2016, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 08, 2016 | Buy | $7.68 | 45,300 | 348,123 | 159,033,143 | Feb 09, 2016, 06:44 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 05, 2016 | Buy | $8.24 | 18,000 | 148,233 | 158,987,843 | Feb 08, 2016, 07:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 04, 2016 | Buy | $7.91 | 5,400 | 42,739 | 158,969,843 | Feb 05, 2016, 08:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 03, 2016 | Buy | $7.70 | 15,400 | 118,592 | 158,964,443 | Feb 04, 2016, 07:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 02, 2016 | Buy | $7.74 | 35,800 | 277,135 | 158,949,043 | Feb 03, 2016, 09:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 01, 2016 | Buy | $7.86 | 16,200 | 127,288 | 158,913,243 | Feb 02, 2016, 08:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 28, 2016 | Buy | $7.71 | 32,800 | 252,797 | 158,897,043 | Jan 29, 2016, 07:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 27, 2016 | Buy | $7.85 | 39,800 | 312,267 | 158,864,243 | Jan 28, 2016, 07:25 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 26, 2016 | Buy | $7.83 | 15,000 | 117,513 | 158,824,443 | Jan 27, 2016, 07:09 AM |
| BARON ROBERT A | Director | Jan 22, 2016 | Option Exercise | $8.24 | 4,224 | 34,806 | 321,588 | Jan 26, 2016, 08:35 PM |
| BARON ROBERT A | Director | Jan 22, 2016 | Option Exercise | $1.16 | 30,000 | 34,800 | 325,812 | Jan 26, 2016, 08:35 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 25, 2016 | Buy | $7.99 | 25,200 | 201,278 | 158,809,443 | Jan 26, 2016, 07:37 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 21, 2016 | Buy | $7.85 | 20,000 | 156,994 | 158,784,243 | Jan 22, 2016, 07:47 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 20, 2016 | Buy | $7.55 | 58,600 | 442,250 | 158,764,243 | Jan 21, 2016, 07:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 19, 2016 | Buy | $7.80 | 23,400 | 182,589 | 158,705,643 | Jan 20, 2016, 07:46 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 15, 2016 | Buy | $7.87 | 65,400 | 515,020 | 158,682,243 | Jan 19, 2016, 08:56 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 14, 2016 | Buy | $7.93 | 10,000 | 79,314 | 158,616,843 | Jan 15, 2016, 07:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 13, 2016 | Buy | $8.29 | 18,000 | 149,173 | 158,606,843 | Jan 14, 2016, 09:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 12, 2016 | Buy | $8.58 | 20,000 | 171,535 | 158,588,843 | Jan 13, 2016, 07:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 11, 2016 | Buy | $8.51 | 10,000 | 85,104 | 158,568,843 | Jan 12, 2016, 06:57 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 08, 2016 | Buy | $8.79 | 10,000 | 87,897 | 158,558,843 | Jan 11, 2016, 07:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 07, 2016 | Buy | $8.86 | 25,000 | 221,495 | 158,548,843 | Jan 08, 2016, 07:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 06, 2016 | Buy | $9.23 | 50,000 | 461,607 | 158,523,843 | Jan 07, 2016, 07:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 05, 2016 | Buy | $9.83 | 30,000 | 294,920 | 158,473,843 | Jan 06, 2016, 07:22 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 30, 2015 | Buy | $10.12 | 20,000 | 202,378 | 158,424,243 | Dec 31, 2015, 09:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 24, 2015 | Buy | $10.16 | 9,900 | 100,615 | 158,404,243 | Dec 28, 2015, 08:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 23, 2015 | Buy | $10.11 | 18,000 | 182,065 | 158,394,343 | Dec 24, 2015, 07:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 22, 2015 | Buy | $9.99 | 20,000 | 199,878 | 158,376,343 | Dec 23, 2015, 07:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 18, 2015 | Buy | $10.00 | 21,800 | 218,013 | 158,356,343 | Dec 21, 2015, 06:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 14, 2015 | Buy | $9.72 | 106,000 | 1,029,811 | 158,334,543 | Dec 15, 2015, 08:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 11, 2015 | Buy | $10.47 | 20,000 | 209,380 | 158,228,543 | Dec 14, 2015, 07:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 09, 2015 | Buy | $10.86 | 30,000 | 325,926 | 158,208,543 | Dec 10, 2015, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 07, 2015 | Buy | $10.99 | 20,000 | 219,793 | 158,178,543 | Dec 08, 2015, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 30, 2015 | Buy | $10.94 | 5,000 | 54,696 | 158,158,543 | Dec 01, 2015, 07:42 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 27, 2015 | Buy | $11.06 | 1,800 | 19,911 | 158,153,543 | Nov 30, 2015, 09:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 25, 2015 | Buy | $11.03 | 17,000 | 187,432 | 158,151,743 | Nov 27, 2015, 09:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 24, 2015 | Buy | $10.76 | 18,000 | 193,706 | 158,134,743 | Nov 25, 2015, 07:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 20, 2015 | Buy | $10.89 | 2,300 | 25,048 | 158,116,743 | Nov 23, 2015, 07:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 19, 2015 | Buy | $10.73 | 30,000 | 321,819 | 158,114,443 | Nov 20, 2015, 06:56 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 16, 2015 | Buy | $10.52 | 30,000 | 315,637 | 158,084,443 | Nov 17, 2015, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 06, 2015 | Buy | $9.83 | 25,000 | 245,813 | 158,054,443 | Nov 09, 2015, 07:40 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 05, 2015 | Buy | $9.63 | 15,000 | 144,458 | 158,029,443 | Nov 06, 2015, 07:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 04, 2015 | Buy | $9.68 | 15,000 | 145,200 | 158,014,443 | Nov 05, 2015, 08:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 03, 2015 | Buy | $9.76 | 15,000 | 146,442 | 157,999,443 | Nov 04, 2015, 07:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 02, 2015 | Buy | $9.76 | 15,000 | 146,399 | 157,984,443 | Nov 03, 2015, 08:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 30, 2015 | Buy | $9.39 | 20,000 | 187,753 | 157,969,443 | Nov 02, 2015, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 29, 2015 | Buy | $9.42 | 25,000 | 235,449 | 157,949,443 | Oct 30, 2015, 08:35 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 28, 2015 | Buy | $9.46 | 25,000 | 236,490 | 157,924,443 | Oct 29, 2015, 09:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 22, 2015 | Buy | $8.90 | 31,800 | 283,101 | 157,899,443 | Oct 23, 2015, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 13, 2015 | Buy | $8.54 | 20,000 | 170,866 | 157,867,643 | Oct 14, 2015, 07:16 AM |
| Yu Alice Lin-Tsing | Director | Oct 08, 2015 | Option Exercise | $3.43 | 20,000 | 68,600 | 80,000 | Oct 09, 2015, 04:23 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 02, 2015 | Buy | $8.40 | 1,800 | 15,127 | 157,847,643 | Oct 05, 2015, 08:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 01, 2015 | Buy | $8.33 | 105,000 | 874,307 | 157,845,843 | Oct 02, 2015, 07:19 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 30, 2015 | Buy | $8.35 | 70,000 | 584,204 | 157,793,343 | Oct 01, 2015, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 29, 2015 | Buy | $8.38 | 30,000 | 251,442 | 157,723,343 | Sep 30, 2015, 07:37 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 25, 2015 | Buy | $9.08 | 202,900 | 1,841,480 | 157,693,343 | Sep 28, 2015, 08:42 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 23, 2015 | Buy | $9.56 | 50,000 | 478,172 | 157,490,443 | Sep 24, 2015, 06:54 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 22, 2015 | Buy | $9.74 | 43,200 | 420,819 | 157,440,443 | Sep 23, 2015, 06:35 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 21, 2015 | Buy | $10.02 | 27,000 | 270,550 | 157,397,243 | Sep 22, 2015, 06:04 AM |
| PAGANELLI JOHN A | Director | Sep 18, 2015 | Option Exercise | $10.48 | 3,517 | 36,858 | 331,208 | Sep 22, 2015, 06:03 AM |
| PAGANELLI JOHN A | Director | Sep 18, 2015 | Option Exercise | $1.05 | 35,000 | 36,850 | 334,725 | Sep 22, 2015, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 18, 2015 | Buy | $10.41 | 12,600 | 131,192 | 157,370,243 | Sep 21, 2015, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 17, 2015 | Buy | $10.34 | 5,400 | 55,833 | 157,357,643 | Sep 18, 2015, 07:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 16, 2015 | Buy | $10.16 | 32,400 | 329,102 | 157,352,243 | Sep 17, 2015, 07:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 14, 2015 | Buy | $10.03 | 15,000 | 150,400 | 157,319,843 | Sep 15, 2015, 07:07 AM |
| Logal Adam | Sr. Vice President, CFO | Sep 14, 2015 | Buy | $9.95 | 1,000 | 9,949 | 45,789 | Sep 15, 2015, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 11, 2015 | Buy | $10.03 | 110,600 | 1,109,628 | 157,304,843 | Sep 14, 2015, 07:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 09, 2015 | Buy | $10.46 | 27,200 | 284,541 | 157,194,243 | Sep 10, 2015, 07:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 08, 2015 | Buy | $10.64 | 7,200 | 76,590 | 157,167,043 | Sep 09, 2015, 08:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 04, 2015 | Buy | $10.67 | 16,200 | 172,886 | 157,159,843 | Sep 08, 2015, 08:51 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 03, 2015 | Buy | $10.96 | 9,000 | 98,621 | 157,143,643 | Sep 04, 2015, 07:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 31, 2015 | Buy | $10.83 | 73,200 | 792,544 | 157,134,643 | Sep 01, 2015, 07:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 28, 2015 | Buy | $11.32 | 12,600 | 142,637 | 157,061,443 | Aug 31, 2015, 07:21 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 27, 2015 | Buy | $11.05 | 46,800 | 517,325 | 157,048,843 | Aug 28, 2015, 07:20 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Aug 25, 2015 | Buy | $10.82 | 20,000 | 216,324 | 24,591,033 | Aug 26, 2015, 07:19 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 24, 2015 | Buy | $10.99 | 223,600 | 2,458,078 | 157,002,043 | Aug 25, 2015, 07:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 21, 2015 | Buy | $12.24 | 185,000 | 2,264,345 | 156,778,443 | Aug 24, 2015, 07:53 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 20, 2015 | Buy | $12.32 | 544,000 | 6,702,134 | 156,559,068 | Aug 20, 2015, 05:09 PM |
| Rubin Steven D | Executive VP-Administration | Aug 20, 2015 | Buy | $12.40 | 2,000 | 24,799 | 5,441,407 | Aug 20, 2015, 05:09 PM |
| Yu Alice Lin-Tsing | Director | Aug 18, 2015 | Option Exercise | $2.05 | 20,000 | 41,000 | 60,000 | Aug 19, 2015, 10:28 AM |
| BARON ROBERT A | Director | Aug 12, 2015 | Option Exercise | $13.45 | 153 | 2,058 | 295,812 | Aug 13, 2015, 02:55 PM |
| BARON ROBERT A | Director | Aug 12, 2015 | Option Exercise | $0.41 | 5,000 | 2,050 | 295,965 | Aug 13, 2015, 02:55 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 07, 2015 | Option Exercise | $5.56 | 1,056,574 | 5,878,686 | 3,068,951 | Aug 10, 2015, 08:49 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Aug 07, 2015 | Option Exercise | $7.94 | 200,000 | 1,588,500 | 24,571,033 | Aug 10, 2015, 08:48 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Aug 06, 2015 | Option Exercise | $7.07 | 144,823 | 1,023,899 | 4,617,404 | Aug 07, 2015, 08:50 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 06, 2015 | Option Exercise | $7.07 | 1,049,971 | 7,423,295 | 156,015,068 | Aug 07, 2015, 08:49 AM |
| BEIER THOMAS E | Director | Jul 17, 2015 | Option Exercise | $1.78 | 20,000 | 35,600 | 20,000 | Jul 20, 2015, 04:21 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 08, 2015 | Buy | $16.56 | 7,200 | 119,197 | 154,965,097 | Jul 09, 2015, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 07, 2015 | Buy | $16.64 | 5,400 | 89,838 | 154,957,897 | Jul 08, 2015, 07:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 06, 2015 | Buy | $16.07 | 3,600 | 57,860 | 154,952,497 | Jul 07, 2015, 06:46 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 02, 2015 | Buy | $16.13 | 9,000 | 145,167 | 154,948,897 | Jul 06, 2015, 06:40 AM |
| BARON ROBERT A | Director | Jun 29, 2015 | Buy | $15.81 | 2,000 | 31,630 | 290,965 | Jun 30, 2015, 06:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 29, 2015 | Buy | $15.62 | 7,200 | 112,471 | 154,939,897 | Jun 30, 2015, 06:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 26, 2015 | Buy | $16.07 | 5,400 | 86,779 | 154,932,697 | Jun 29, 2015, 06:58 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 25, 2015 | Buy | $15.39 | 7,200 | 110,774 | 154,927,297 | Jun 26, 2015, 09:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 24, 2015 | Buy | $15.33 | 57,200 | 876,775 | 154,920,097 | Jun 25, 2015, 09:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 23, 2015 | Buy | $15.60 | 9,000 | 140,428 | 154,862,897 | Jun 24, 2015, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 22, 2015 | Buy | $15.66 | 200 | 3,132 | 154,853,897 | Jun 23, 2015, 08:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 22, 2015 | Buy | $15.53 | 23,200 | 360,219 | 154,853,697 | Jun 23, 2015, 08:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 19, 2015 | Buy | $15.33 | 7,200 | 110,363 | 154,830,497 | Jun 22, 2015, 06:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 17, 2015 | Buy | $15.35 | 15,400 | 236,416 | 154,823,297 | Jun 18, 2015, 07:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 16, 2015 | Buy | $15.36 | 10,000 | 153,628 | 154,807,897 | Jun 17, 2015, 06:54 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 12, 2015 | Buy | $15.51 | 10,000 | 155,099 | 154,797,897 | Jun 15, 2015, 06:43 AM |
| PAGANELLI JOHN A | Director | Jun 11, 2015 | Buy | $15.90 | 4,175 | 66,380 | 4,175 | Jun 12, 2015, 07:41 AM |
| BARON ROBERT A | Director | Jun 10, 2015 | Buy | $16.06 | 3,000 | 48,180 | 288,965 | Jun 11, 2015, 08:47 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 09, 2015 | Buy | $15.95 | 15,000 | 239,280 | 154,787,897 | Jun 10, 2015, 07:21 AM |
| LERNER RICHARD A | Director | Jun 09, 2015 | Buy | $16.02 | 2,100 | 33,637 | 5,600 | Jun 09, 2015, 04:15 PM |
| LERNER RICHARD A | Director | Jun 05, 2015 | Buy | $15.87 | 10,400 | 165,084 | 20,000 | Jun 09, 2015, 04:15 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 13, 2015 | Buy | $15.55 | 6,000 | 93,318 | 154,772,897 | May 14, 2015, 07:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 12, 2015 | Buy | $14.76 | 6,000 | 88,534 | 154,766,897 | May 13, 2015, 06:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 11, 2015 | Buy | $14.30 | 6,000 | 85,825 | 154,760,897 | May 12, 2015, 06:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 08, 2015 | Buy | $14.14 | 9,000 | 127,268 | 154,754,897 | May 11, 2015, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 07, 2015 | Buy | $14.06 | 9,000 | 126,521 | 154,745,897 | May 08, 2015, 07:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 06, 2015 | Buy | $13.93 | 12,600 | 175,463 | 154,736,897 | May 07, 2015, 07:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 05, 2015 | Buy | $13.93 | 9,000 | 125,401 | 154,724,297 | May 06, 2015, 06:42 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 04, 2015 | Buy | $14.27 | 7,200 | 102,777 | 154,715,297 | May 05, 2015, 07:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 01, 2015 | Buy | $14.03 | 6,700 | 94,017 | 154,708,097 | May 04, 2015, 06:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 30, 2015 | Buy | $13.95 | 31,300 | 436,669 | 154,701,397 | May 01, 2015, 09:40 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 29, 2015 | Buy | $14.37 | 15,500 | 222,680 | 154,670,097 | Apr 30, 2015, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 28, 2015 | Buy | $14.45 | 8,000 | 115,637 | 154,654,597 | Apr 29, 2015, 07:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 27, 2015 | Buy | $14.47 | 8,800 | 127,358 | 154,646,597 | Apr 28, 2015, 06:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 24, 2015 | Buy | $14.80 | 4,100 | 60,696 | 154,637,797 | Apr 27, 2015, 06:29 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 21, 2015 | Buy | $14.30 | 5,700 | 81,526 | 154,633,697 | Apr 22, 2015, 06:50 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 17, 2015 | Buy | $14.29 | 19,800 | 282,973 | 154,627,997 | Apr 20, 2015, 06:44 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 16, 2015 | Buy | $14.63 | 10,800 | 158,013 | 154,608,197 | Apr 17, 2015, 07:22 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 10, 2015 | Buy | $14.22 | 7,200 | 102,392 | 154,597,397 | Apr 13, 2015, 07:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 09, 2015 | Buy | $14.26 | 12,600 | 179,669 | 154,590,197 | Apr 10, 2015, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 08, 2015 | Buy | $14.26 | 10,800 | 154,016 | 154,577,597 | Apr 09, 2015, 06:57 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 07, 2015 | Buy | $14.29 | 5,400 | 77,141 | 154,566,797 | Apr 08, 2015, 06:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 06, 2015 | Buy | $14.21 | 10,800 | 153,498 | 154,561,397 | Apr 07, 2015, 07:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 02, 2015 | Buy | $14.34 | 3,600 | 51,620 | 154,550,597 | Apr 03, 2015, 07:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 01, 2015 | Buy | $14.14 | 9,000 | 127,295 | 154,546,997 | Apr 02, 2015, 07:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 31, 2015 | Buy | $14.29 | 23,400 | 334,307 | 154,537,997 | Apr 01, 2015, 06:37 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 25, 2015 | Buy | $14.15 | 32,400 | 458,366 | 154,514,597 | Mar 26, 2015, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 20, 2015 | Buy | $14.50 | 14,400 | 208,831 | 154,482,197 | Mar 23, 2015, 08:31 AM |
| Logal Adam | Sr. Vice President, CFO | Mar 12, 2015 | Option Exercise | $14.60 | 8,723 | 127,356 | 86,277 | Mar 13, 2015, 05:12 PM |
| Logal Adam | Sr. Vice President, CFO | Mar 12, 2015 | Option Exercise | $1.34 | 95,000 | 127,350 | 90,233 | Mar 13, 2015, 05:12 PM |
| Logal Adam | Sr. Vice President, CFO | Mar 13, 2015 | Sale | $14.64 | 41,488 | 607,360 | 86,253 | Mar 13, 2015, 05:12 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 10, 2015 | Buy | $13.86 | 5,400 | 74,828 | 154,467,797 | Mar 11, 2015, 09:21 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 09, 2015 | Buy | $13.98 | 10,800 | 151,002 | 154,462,397 | Mar 10, 2015, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 06, 2015 | Buy | $14.17 | 12,600 | 178,503 | 154,451,597 | Mar 09, 2015, 07:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 05, 2015 | Buy | $14.34 | 5,400 | 77,423 | 154,438,997 | Mar 06, 2015, 06:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 04, 2015 | Buy | $14.35 | 10,800 | 154,932 | 154,433,597 | Mar 05, 2015, 06:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 03, 2015 | Buy | $14.12 | 18,200 | 256,906 | 154,422,797 | Mar 04, 2015, 06:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 02, 2015 | Buy | $13.98 | 44,800 | 626,481 | 154,404,597 | Mar 03, 2015, 06:25 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 13, 2015 | Buy | $13.61 | 25,000 | 340,231 | 154,359,797 | Feb 17, 2015, 07:19 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 03, 2015 | Buy | $12.16 | 25,000 | 304,082 | 154,334,797 | Feb 04, 2015, 09:13 AM |
| Rubin Steven D | Executive VP-Administration | Jan 31, 2015 | Option Exercise | $11.78 | 75,299 | 886,796 | 5,439,407 | Feb 02, 2015, 06:02 AM |
| Rubin Steven D | Executive VP-Administration | Jan 31, 2015 | Option Exercise | $11.76 | 195,642 | 2,300,611 | 20,112,585 | Feb 02, 2015, 06:02 AM |
| Rubin Steven D | Executive VP-Administration | Jan 31, 2015 | Option Exercise | $0.86 | 1,036,440 | 886,744 | 5,514,706 | Feb 02, 2015, 06:02 AM |
| Rubin Steven D | Executive VP-Administration | Jan 31, 2015 | Option Exercise | $0.48 | 4,796,158 | 2,300,550 | 20,286,704 | Feb 02, 2015, 06:02 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Jan 31, 2015 | Option Exercise | $11.76 | 195,642 | 2,300,611 | 20,112,585 | Feb 02, 2015, 06:01 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Jan 31, 2015 | Option Exercise | $11.78 | 213,342 | 2,512,529 | 24,371,033 | Feb 02, 2015, 06:01 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Jan 31, 2015 | Option Exercise | $0.48 | 4,796,158 | 2,300,550 | 20,286,704 | Feb 02, 2015, 06:01 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Jan 31, 2015 | Option Exercise | $0.86 | 2,936,580 | 2,512,440 | 24,584,375 | Feb 02, 2015, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 31, 2015 | Option Exercise | $11.77 | 906,146 | 10,668,217 | 154,309,797 | Feb 02, 2015, 06:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 31, 2015 | Option Exercise | $0.71 | 8,055,976 | 5,712,275 | 148,289,847 | Feb 02, 2015, 06:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 28, 2015 | Buy | $11.27 | 15,000 | 169,097 | 145,030,029 | Jan 29, 2015, 08:51 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 23, 2015 | Buy | $10.84 | 10,000 | 108,397 | 145,015,029 | Jan 26, 2015, 09:28 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 22, 2015 | Buy | $10.52 | 28,000 | 294,581 | 145,005,029 | Jan 23, 2015, 09:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 21, 2015 | Buy | $10.23 | 41,700 | 426,666 | 144,977,029 | Jan 22, 2015, 07:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 20, 2015 | Buy | $10.11 | 45,000 | 455,026 | 144,935,329 | Jan 21, 2015, 09:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 16, 2015 | Buy | $10.01 | 25,000 | 250,193 | 144,890,329 | Jan 20, 2015, 07:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 15, 2015 | Buy | $10.00 | 44,000 | 439,912 | 144,865,329 | Jan 16, 2015, 08:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 13, 2015 | Buy | $10.15 | 25,000 | 253,714 | 144,821,329 | Jan 14, 2015, 08:42 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 09, 2015 | Buy | $10.10 | 9,200 | 92,928 | 144,796,329 | Jan 12, 2015, 07:37 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 08, 2015 | Buy | $10.03 | 22,300 | 223,718 | 144,787,129 | Jan 09, 2015, 09:54 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 06, 2015 | Buy | $9.92 | 26,000 | 257,913 | 144,764,829 | Jan 07, 2015, 07:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jan 02, 2015 | Buy | $9.92 | 28,000 | 277,714 | 144,738,829 | Jan 05, 2015, 09:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 31, 2014 | Buy | $9.99 | 92,500 | 924,110 | 144,710,829 | Jan 02, 2015, 09:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 23, 2014 | Buy | $9.46 | 40,000 | 378,253 | 144,618,329 | Dec 24, 2014, 09:47 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 22, 2014 | Buy | $9.79 | 10,000 | 97,902 | 144,578,329 | Dec 23, 2014, 09:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Dec 17, 2014 | Buy | $9.06 | 15,000 | 135,957 | 144,568,329 | Dec 18, 2014, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 21, 2014 | Buy | $8.15 | 40,000 | 325,811 | 144,553,329 | Nov 24, 2014, 08:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 20, 2014 | Buy | $8.11 | 62,500 | 507,112 | 144,513,329 | Nov 21, 2014, 09:21 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 19, 2014 | Buy | $8.17 | 25,000 | 204,272 | 144,450,829 | Nov 20, 2014, 09:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 17, 2014 | Buy | $8.23 | 22,000 | 181,100 | 144,425,829 | Nov 18, 2014, 06:51 AM |
| BEIER THOMAS E | Director | Nov 14, 2014 | Option Exercise | $2.78 | 10,227 | 28,431 | 30,227 | Nov 17, 2014, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 14, 2014 | Buy | $8.27 | 20,000 | 165,436 | 144,403,829 | Nov 17, 2014, 07:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 13, 2014 | Buy | $8.35 | 12,400 | 103,508 | 144,383,829 | Nov 14, 2014, 06:59 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 12, 2014 | Option Exercise | $0.00 | 210,821 | 401 | 144,303,629 | Nov 13, 2014, 07:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 12, 2014 | Buy | $8.39 | 67,800 | 568,507 | 144,371,429 | Nov 13, 2014, 07:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 07, 2014 | Buy | $8.28 | 90,000 | 745,056 | 144,092,808 | Nov 10, 2014, 08:47 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 06, 2014 | Buy | $8.38 | 28,600 | 239,597 | 144,002,808 | Nov 07, 2014, 06:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 05, 2014 | Buy | $8.35 | 33,200 | 277,171 | 143,974,208 | Nov 06, 2014, 07:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 04, 2014 | Buy | $8.35 | 33,600 | 280,655 | 143,941,008 | Nov 05, 2014, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 03, 2014 | Buy | $8.36 | 23,600 | 197,280 | 143,907,408 | Nov 04, 2014, 06:16 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 31, 2014 | Buy | $8.38 | 20,000 | 167,680 | 143,883,808 | Nov 03, 2014, 06:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 30, 2014 | Buy | $8.33 | 32,500 | 270,811 | 143,863,808 | Oct 31, 2014, 06:47 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 29, 2014 | Buy | $8.38 | 35,000 | 293,474 | 143,831,308 | Oct 30, 2014, 06:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 24, 2014 | Buy | $8.40 | 40,000 | 336,149 | 143,796,308 | Oct 27, 2014, 09:34 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 22, 2014 | Buy | $8.22 | 64,800 | 532,953 | 143,756,308 | Oct 23, 2014, 06:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 17, 2014 | Buy | $8.25 | 30,000 | 247,425 | 143,691,508 | Oct 20, 2014, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 16, 2014 | Buy | $8.33 | 20,000 | 166,524 | 143,661,508 | Oct 17, 2014, 06:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 13, 2014 | Buy | $8.20 | 54,000 | 442,584 | 143,641,508 | Oct 14, 2014, 09:38 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 10, 2014 | Buy | $8.18 | 82,300 | 673,363 | 143,587,508 | Oct 14, 2014, 07:04 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 09, 2014 | Buy | $8.41 | 25,000 | 210,209 | 143,505,208 | Oct 10, 2014, 07:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 08, 2014 | Buy | $8.39 | 20,000 | 167,889 | 143,480,208 | Oct 09, 2014, 06:16 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 07, 2014 | Buy | $8.29 | 55,000 | 456,054 | 143,460,208 | Oct 08, 2014, 09:58 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 06, 2014 | Buy | $8.36 | 10,000 | 83,601 | 143,405,208 | Oct 07, 2014, 07:48 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 03, 2014 | Buy | $8.41 | 29,400 | 247,298 | 143,395,208 | Oct 06, 2014, 06:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 02, 2014 | Buy | $8.31 | 35,000 | 290,945 | 143,365,808 | Oct 03, 2014, 06:35 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 01, 2014 | Buy | $8.38 | 40,000 | 335,246 | 143,330,808 | Oct 02, 2014, 09:24 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 30, 2014 | Buy | $8.56 | 25,000 | 213,961 | 143,290,808 | Oct 01, 2014, 07:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 26, 2014 | Buy | $8.57 | 24,000 | 205,592 | 143,265,808 | Sep 29, 2014, 09:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 25, 2014 | Buy | $8.51 | 10,000 | 85,150 | 143,241,808 | Sep 26, 2014, 09:15 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Sep 24, 2014 | Option Exercise | $2.48 | 201,613 | 500,000 | 4,472,581 | Sep 25, 2014, 04:16 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 24, 2014 | Buy | $8.23 | 63,000 | 518,578 | 143,231,808 | Sep 25, 2014, 08:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 23, 2014 | Buy | $8.42 | 6,100 | 51,390 | 143,168,808 | Sep 24, 2014, 10:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 23, 2014 | Buy | $8.31 | 64,000 | 531,694 | 143,162,808 | Sep 24, 2014, 10:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 19, 2014 | Buy | $8.41 | 35,000 | 294,460 | 143,098,708 | Sep 22, 2014, 06:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 18, 2014 | Buy | $8.49 | 40,000 | 339,418 | 143,063,708 | Sep 19, 2014, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 16, 2014 | Buy | $8.49 | 25,000 | 212,185 | 143,023,708 | Sep 17, 2014, 07:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 15, 2014 | Buy | $8.52 | 20,000 | 170,338 | 142,998,708 | Sep 16, 2014, 06:32 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 12, 2014 | Buy | $8.57 | 15,000 | 128,600 | 142,978,708 | Sep 15, 2014, 06:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 11, 2014 | Buy | $8.54 | 20,000 | 170,844 | 142,963,708 | Sep 12, 2014, 06:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 10, 2014 | Buy | $8.55 | 10,000 | 85,495 | 142,943,708 | Sep 11, 2014, 06:34 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 09, 2014 | Buy | $8.55 | 35,700 | 305,129 | 142,933,708 | Sep 10, 2014, 09:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 05, 2014 | Buy | $8.48 | 58,000 | 492,038 | 142,898,008 | Sep 08, 2014, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 04, 2014 | Buy | $8.60 | 35,000 | 301,116 | 142,840,008 | Sep 05, 2014, 06:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Sep 02, 2014 | Buy | $8.78 | 10,000 | 87,847 | 142,805,008 | Sep 03, 2014, 06:32 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 29, 2014 | Buy | $8.91 | 20,000 | 178,260 | 142,795,008 | Sep 02, 2014, 06:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 28, 2014 | Buy | $8.84 | 30,000 | 265,068 | 142,775,008 | Aug 29, 2014, 07:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 22, 2014 | Buy | $8.81 | 31,000 | 272,965 | 142,710,008 | Aug 25, 2014, 11:31 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 21, 2014 | Buy | $8.81 | 25,000 | 220,224 | 142,679,008 | Aug 22, 2014, 07:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 20, 2014 | Buy | $8.91 | 35,000 | 311,853 | 142,654,008 | Aug 21, 2014, 09:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 19, 2014 | Buy | $9.06 | 10,000 | 90,594 | 142,619,008 | Aug 20, 2014, 07:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 15, 2014 | Buy | $9.09 | 11,400 | 103,572 | 142,609,008 | Aug 18, 2014, 07:52 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 14, 2014 | Buy | $9.04 | 19,300 | 174,509 | 142,597,608 | Aug 15, 2014, 06:42 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 12, 2014 | Buy | $8.97 | 63,000 | 565,154 | 142,578,308 | Aug 13, 2014, 06:40 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 04, 2014 | Buy | $8.75 | 5,000 | 43,756 | 142,515,308 | Aug 05, 2014, 09:03 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Aug 01, 2014 | Option Exercise | $4.80 | 309,583 | 1,485,533 | 21,647,795 | Aug 04, 2014, 07:19 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 01, 2014 | Buy | $8.67 | 25,000 | 216,666 | 142,510,308 | Aug 04, 2014, 08:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 30, 2014 | Buy | $8.97 | 25,000 | 224,330 | 142,485,308 | Jul 31, 2014, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 29, 2014 | Buy | $9.06 | 18,500 | 167,559 | 142,460,308 | Jul 31, 2014, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 28, 2014 | Option Exercise | $2.48 | 630,048 | 1,562,519 | 142,441,808 | Jul 29, 2014, 05:00 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 28, 2014 | Option Exercise | $0.66 | 24,877 | 16,419 | 2,012,377 | Jul 29, 2014, 05:00 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 25, 2014 | Buy | $9.01 | 36,000 | 324,521 | 141,811,760 | Jul 28, 2014, 06:57 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 23, 2014 | Buy | $8.90 | 10,000 | 88,997 | 141,775,759 | Jul 24, 2014, 07:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 22, 2014 | Buy | $8.66 | 30,000 | 259,884 | 141,765,759 | Jul 23, 2014, 07:23 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 17, 2014 | Buy | $8.63 | 40,000 | 345,349 | 141,735,759 | Jul 18, 2014, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 16, 2014 | Buy | $8.76 | 20,000 | 175,234 | 141,695,759 | Jul 17, 2014, 06:53 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 15, 2014 | Buy | $8.73 | 26,000 | 227,021 | 141,675,759 | Jul 16, 2014, 06:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 14, 2014 | Buy | $8.91 | 20,000 | 178,137 | 141,649,759 | Jul 15, 2014, 06:27 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 10, 2014 | Buy | $8.79 | 20,000 | 175,890 | 141,629,759 | Jul 11, 2014, 07:39 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 08, 2014 | Buy | $8.58 | 30,000 | 257,503 | 141,609,759 | Jul 09, 2014, 06:06 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 07, 2014 | Buy | $8.79 | 27,000 | 237,436 | 141,579,759 | Jul 08, 2014, 06:54 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 03, 2014 | Buy | $8.90 | 45,800 | 407,774 | 141,552,759 | Jul 07, 2014, 06:31 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 02, 2014 | Buy | $8.78 | 13,000 | 114,120 | 141,506,959 | Jul 03, 2014, 06:58 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jul 01, 2014 | Buy | $8.90 | 15,000 | 133,535 | 141,493,959 | Jul 02, 2014, 07:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 30, 2014 | Buy | $8.94 | 15,000 | 134,144 | 141,478,959 | Jul 01, 2014, 06:11 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 27, 2014 | Buy | $8.96 | 20,000 | 179,229 | 141,463,959 | Jun 30, 2014, 06:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 25, 2014 | Buy | $8.65 | 65,000 | 562,443 | 141,443,959 | Jun 26, 2014, 07:12 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 24, 2014 | Buy | $8.85 | 40,000 | 353,857 | 141,378,959 | Jun 25, 2014, 06:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 23, 2014 | Buy | $9.05 | 15,000 | 135,797 | 141,338,959 | Jun 24, 2014, 07:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 20, 2014 | Buy | $9.17 | 45,000 | 412,737 | 141,323,959 | Jun 23, 2014, 06:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 19, 2014 | Buy | $9.25 | 50,000 | 462,492 | 141,278,959 | Jun 20, 2014, 07:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 18, 2014 | Buy | $9.35 | 20,000 | 187,064 | 141,228,959 | Jun 19, 2014, 08:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 12, 2014 | Buy | $9.03 | 50,000 | 451,343 | 141,208,959 | Jun 13, 2014, 07:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 11, 2014 | Buy | $9.09 | 50,000 | 454,628 | 141,158,959 | Jun 12, 2014, 07:22 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 10, 2014 | Buy | $9.16 | 20,500 | 187,754 | 141,108,959 | Jun 11, 2014, 06:01 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 06, 2014 | Buy | $9.30 | 10,000 | 93,015 | 141,088,459 | Jun 09, 2014, 07:23 AM |
| Yu Alice Lin-Tsing | Director | Jun 05, 2014 | Option Exercise | $1.23 | 20,000 | 24,600 | 40,000 | Jun 06, 2014, 04:56 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Jun 04, 2014 | Buy | $8.78 | 20,000 | 175,619 | 141,078,459 | Jun 05, 2014, 08:25 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 30, 2014 | Buy | $8.60 | 36,000 | 309,758 | 141,058,459 | Jun 02, 2014, 06:09 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 21, 2014 | Buy | $8.30 | 10,000 | 83,022 | 141,022,459 | May 22, 2014, 06:39 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 20, 2014 | Buy | $8.26 | 26,600 | 219,703 | 141,012,459 | May 21, 2014, 06:53 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 15, 2014 | Buy | $8.10 | 24,400 | 197,542 | 140,985,859 | May 16, 2014, 06:35 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 14, 2014 | Buy | $8.20 | 25,500 | 209,142 | 140,961,459 | May 15, 2014, 06:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 13, 2014 | Buy | $8.35 | 20,400 | 170,429 | 140,935,959 | May 14, 2014, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 12, 2014 | Buy | $8.46 | 10,000 | 84,600 | 140,915,559 | May 13, 2014, 07:59 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 09, 2014 | Buy | $8.17 | 100,000 | 816,970 | 140,905,559 | May 12, 2014, 06:29 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 08, 2014 | Buy | $8.06 | 73,900 | 595,971 | 140,805,559 | May 09, 2014, 06:15 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 07, 2014 | Buy | $8.16 | 37,500 | 306,181 | 140,731,659 | May 08, 2014, 06:38 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 06, 2014 | Buy | $8.24 | 33,900 | 279,407 | 140,694,159 | May 07, 2014, 06:25 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 05, 2014 | Buy | $8.36 | 16,500 | 137,915 | 140,660,259 | May 06, 2014, 06:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 02, 2014 | Buy | $8.26 | 26,000 | 214,858 | 140,643,759 | May 05, 2014, 06:10 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | May 01, 2014 | Buy | $8.36 | 20,000 | 167,176 | 140,617,759 | May 02, 2014, 06:36 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 30, 2014 | Buy | $8.22 | 25,000 | 205,593 | 140,597,759 | May 01, 2014, 06:41 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 25, 2014 | Buy | $8.04 | 36,200 | 291,118 | 140,572,759 | Apr 28, 2014, 07:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 24, 2014 | Buy | $8.25 | 12,400 | 102,329 | 140,536,559 | Apr 25, 2014, 07:40 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 23, 2014 | Buy | $8.17 | 36,300 | 296,524 | 140,524,159 | Apr 24, 2014, 07:43 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 22, 2014 | Buy | $8.29 | 89,500 | 741,717 | 140,487,859 | Apr 23, 2014, 06:54 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 21, 2014 | Buy | $8.32 | 100,000 | 832,220 | 140,398,359 | Apr 22, 2014, 07:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 17, 2014 | Buy | $8.15 | 51,000 | 415,668 | 140,298,359 | Apr 21, 2014, 06:50 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 15, 2014 | Buy | $8.04 | 129,800 | 1,043,618 | 140,247,359 | Apr 16, 2014, 09:28 AM |
| HSIAO JANE PH D | Vice Chairman & CTO | Apr 15, 2014 | Buy | $8.03 | 10,000 | 80,300 | 21,338,212 | Apr 15, 2014, 06:22 PM |
| Rubin Steven D | Executive VP-Administration | Apr 11, 2014 | Option Exercise | $8.87 | 312,289 | 2,770,003 | 4,657,566 | Apr 15, 2014, 06:19 PM |
| Rubin Steven D | Executive VP-Administration | Apr 11, 2014 | Option Exercise | $3.96 | 700,000 | 2,770,000 | 4,969,855 | Apr 15, 2014, 06:19 PM |
| Rubin Steven D | Executive VP-Administration | Apr 15, 2014 | Sale | $8.10 | 79,300 | 642,615 | 4,478,266 | Apr 15, 2014, 06:19 PM |
| Rubin Steven D | Executive VP-Administration | Apr 14, 2014 | Sale | $8.58 | 100,000 | 857,700 | 4,557,566 | Apr 15, 2014, 06:19 PM |
| LERNER RICHARD A | Director | Apr 15, 2014 | Option Exercise | $8.17 | 8,128 | 66,406 | 135,749 | Apr 15, 2014, 06:14 PM |
| LERNER RICHARD A | Director | Apr 15, 2014 | Option Exercise | $1.66 | 40,000 | 66,400 | 143,877 | Apr 15, 2014, 06:14 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 14, 2014 | Buy | $8.46 | 110,600 | 935,643 | 140,117,559 | Apr 15, 2014, 09:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 11, 2014 | Buy | $8.81 | 63,400 | 558,741 | 140,006,959 | Apr 14, 2014, 06:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 10, 2014 | Buy | $9.28 | 20,400 | 189,229 | 139,943,559 | Apr 11, 2014, 09:02 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 07, 2014 | Buy | $9.12 | 28,700 | 261,618 | 139,923,159 | Apr 08, 2014, 07:03 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 04, 2014 | Buy | $9.20 | 26,900 | 247,547 | 139,894,459 | Apr 07, 2014, 06:55 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 03, 2014 | Buy | $9.45 | 28,000 | 264,720 | 139,867,559 | Apr 04, 2014, 07:30 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 02, 2014 | Buy | $9.59 | 18,200 | 174,577 | 139,839,559 | Apr 03, 2014, 07:05 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 28, 2014 | Buy | $8.85 | 16 | 142 | 139,791,475 | Mar 31, 2014, 07:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 28, 2014 | Buy | $8.88 | 37,684 | 334,685 | 139,821,359 | Mar 31, 2014, 07:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 27, 2014 | Buy | $9.01 | 26,800 | 241,556 | 139,783,659 | Mar 28, 2014, 07:35 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 26, 2014 | Buy | $9.12 | 52,400 | 477,650 | 139,756,859 | Mar 27, 2014, 07:39 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 25, 2014 | Buy | $9.27 | 16,500 | 152,988 | 139,704,459 | Mar 26, 2014, 06:59 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 24, 2014 | Buy | $9.28 | 21,400 | 198,676 | 139,687,959 | Mar 25, 2014, 06:08 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 21, 2014 | Buy | $9.46 | 30,800 | 291,269 | 139,666,559 | Mar 24, 2014, 07:13 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 20, 2014 | Buy | $9.74 | 34,600 | 336,984 | 139,635,759 | Mar 21, 2014, 07:18 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 19, 2014 | Buy | $9.73 | 15,000 | 146,001 | 139,601,159 | Mar 20, 2014, 07:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 18, 2014 | Buy | $9.95 | 20,500 | 203,978 | 139,586,159 | Mar 19, 2014, 06:14 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 13, 2014 | Buy | $9.32 | 37,000 | 344,779 | 139,565,659 | Mar 14, 2014, 09:45 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 12, 2014 | Buy | $9.25 | 6,000 | 55,504 | 139,528,659 | Mar 13, 2014, 07:48 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 11, 2014 | Buy | $9.12 | 60,900 | 555,582 | 139,522,659 | Mar 12, 2014, 07:40 AM |
| PAGANELLI JOHN A | Director | Mar 10, 2014 | Option Exercise | $9.24 | 25,574 | 236,304 | 299,825 | Mar 11, 2014, 05:32 PM |
| PAGANELLI JOHN A | Director | Mar 10, 2014 | Option Exercise | $2.36 | 100,000 | 236,300 | 325,399 | Mar 11, 2014, 05:32 PM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 10, 2014 | Buy | $9.21 | 9,600 | 88,429 | 139,461,759 | Mar 11, 2014, 07:40 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 07, 2014 | Buy | $9.20 | 10,000 | 92,000 | 139,452,159 | Mar 10, 2014, 09:34 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 06, 2014 | Buy | $9.15 | 41,500 | 379,532 | 139,442,159 | Mar 07, 2014, 09:33 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 05, 2014 | Buy | $9.39 | 15,000 | 140,787 | 139,400,659 | Mar 06, 2014, 07:34 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 28, 2014 | Buy | $9.73 | 15,000 | 145,976 | 139,385,659 | Mar 03, 2014, 10:17 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 27, 2014 | Buy | $9.11 | 15,000 | 136,712 | 139,370,659 | Feb 28, 2014, 10:00 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 26, 2014 | Buy | $9.11 | 1,000 | 9,110 | 139,355,659 | Feb 27, 2014, 09:37 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 26, 2014 | Buy | $8.97 | 14,000 | 125,534 | 139,354,659 | Feb 27, 2014, 09:37 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 25, 2014 | Buy | $9.03 | 15,000 | 135,476 | 139,340,659 | Feb 26, 2014, 09:26 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 24, 2014 | Buy | $8.96 | 15,000 | 134,409 | 139,325,659 | Feb 25, 2014, 07:07 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 21, 2014 | Buy | $9.00 | 17,200 | 154,871 | 139,310,659 | Feb 24, 2014, 09:29 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 20, 2014 | Buy | $8.56 | 27,000 | 231,083 | 139,293,459 | Feb 21, 2014, 06:49 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 19, 2014 | Buy | $8.53 | 27,600 | 235,498 | 139,266,459 | Feb 20, 2014, 06:57 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 18, 2014 | Buy | $8.68 | 20,900 | 181,489 | 139,238,859 | Feb 19, 2014, 08:53 AM |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 14, 2014 | Buy | $8.65 | 20,500 | 177,375 | 139,217,959 | Feb 18, 2014, 09:36 AM |