Nektar Therapeutics. (NKTR) NASDAQ
$0.53 0.04 (7.14%)
Market Cap: $100.15M
As of 12/01/23 04:00 PM EST. Market closed.
Nektar Therapeutics. (NKTR)
NASDAQ
$0.53
0.04 (7.14%)
Market Cap: $100.15M
As of 12/01/23 04:00 PM EST. Market closed.
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nektar therapeutics is a leading biopharmaceutical company developing a robust pipeline of novel therapeutics based on its advanced polymer conjugate chemistry technology platform. nektar also partners with the top biopharmaceutical companies to bring new products to market. to date, nektar's technology and drug development expertise have enabled nine approved products for partners, which include ... read more
nektar therapeutics is a leading biopharmaceutical company developing a robust pipeline of novel therapeutics based on its advanced polymer conjugate chemistry technology platform. nektar also partners with the top biopharmaceutical companies to bring new products to market. to date, nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading biopharmaceutical companies. read less
COMPANY PROFILE
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
Howard Robin
Full Time Employees
820
CEO Compensation (Base)
$968,921
CEO Compensation (Total)
$13.33M
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
Howard Robin
Full Time Employees
820
CEO Compensation (Base)
$968,921
CEO Compensation (Total)
$13.33M
URL
Address
455 Mission Bay Blvd S, California, San Francisco, 94158-2158.
PRICE CHART FOR NEKTAR THERAPEUTICS
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NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
$0.49
Previous Close
$0.49
Days Range
$0.47 - $0.53
52 week range
$0.41 - $3.19
Volume
1,130,470
Avg. Volume (30 days)
1,625,170
Market Cap
$100.15M
Dividend Yield
-
P/E
(0.34)
Shares Outstanding
190,770,566
Open
$0.49
Previous Close
$0.49
Days Range
$0.47 - $0.53
52 week range
$0.41 - $3.19
Volume
1,130,470
Avg. Volume (30 days)
1,625,170
Market Cap
$100.15M
Dividend Yield
-
P/E
(0.34)
Shares Outstanding
190,770,566
FINANCIAL STATEMENTS FOR NEKTAR THERAPEUTICS
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INSIDER TRANSACTIONS FOR NEKTAR THERAPEUTICS
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| Zalevsky Jonathan | Chief R&D Officer | Nov 17, 2023 | Sale | $0.49 | 9,646 | 4,727 | 274,039 | Nov 20, 2023, 09:02 PM |
| Wilson Mark Andrew | Chief Legal Officer | Nov 17, 2023 | Sale | $0.49 | 7,179 | 3,518 | 243,780 | Nov 20, 2023, 09:00 PM |
| ROBIN HOWARD W | President & CEO | Nov 17, 2023 | Sale | $0.49 | 19,877 | 9,740 | 899,922 | Nov 20, 2023, 08:58 PM |
| Curet Myriam | Director | Sep 18, 2023 | Sale | $0.69 | 4,359 | 3,008 | 27,418 | Sep 20, 2023, 08:09 PM |
| CHESS ROBERT | Director | Sep 22, 2022 | Sale | $0.67 | 10,200 | 6,834 | 274,773 | Sep 20, 2023, 08:08 PM |
| Ajer Jeffrey Robert | Director | Sep 18, 2023 | Sale | $0.69 | 4,359 | 3,008 | 34,153 | Sep 20, 2023, 08:06 PM |
| Zalevsky Jonathan | Chief R&D Officer | Aug 16, 2023 | Sale | $0.78 | 9,703 | 7,568 | 283,685 | Aug 17, 2023, 08:08 PM |
| Wilson Mark Andrew | Chief Legal Officer | Aug 16, 2023 | Sale | $0.78 | 7,221 | 5,632 | 250,959 | Aug 17, 2023, 08:07 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2023 | Sale | $0.78 | 19,998 | 15,598 | 919,799 | Aug 17, 2023, 08:06 PM |
| WHITFIELD ROY A | Director | Jun 14, 2023 | Sale | $0.57 | 30,000 | 17,100 | 216,250 | Jun 15, 2023, 06:26 PM |
| Zalevsky Jonathan | Chief R&D Officer | May 16, 2023 | Sale | $0.72 | 9,791 | 7,050 | 293,388 | May 17, 2023, 08:29 PM |
| Wilson Mark Andrew | Chief Legal Officer | May 16, 2023 | Sale | $0.72 | 7,543 | 5,431 | 257,680 | May 17, 2023, 08:28 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2023 | Sale | $0.72 | 20,361 | 14,660 | 939,797 | May 17, 2023, 08:27 PM |
| Zalevsky Jonathan | Chief R&D Officer | Feb 16, 2023 | Sale | $3.00 | 10,484 | 31,452 | 303,179 | Feb 17, 2023, 09:00 PM |
| Wilson Mark Andrew | Chief Legal Officer | Feb 16, 2023 | Sale | $3.00 | 8,275 | 24,825 | 265,223 | Feb 17, 2023, 08:59 PM |
| Thomsen Jillian B. | Chief Financial Officer | Feb 16, 2023 | Sale | $3.00 | 10,267 | 30,801 | 313,497 | Feb 17, 2023, 08:58 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2023 | Sale | $3.00 | 19,635 | 58,905 | 960,158 | Feb 17, 2023, 08:57 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 16, 2022 | Sale | $3.57 | 13,460 | 48,052 | 313,663 | Nov 18, 2022, 06:05 PM |
| Wilson Mark Andrew | Chief Legal Officer | Nov 16, 2022 | Sale | $3.57 | 8,690 | 31,023 | 272,498 | Nov 18, 2022, 06:04 PM |
| Thomsen Jillian B. | Chief Financial Officer | Nov 16, 2022 | Sale | $3.57 | 11,095 | 39,609 | 323,764 | Nov 18, 2022, 06:03 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2022 | Sale | $3.57 | 38,014 | 135,710 | 979,793 | Nov 18, 2022, 06:02 PM |
| Curet Myriam | Director | Sep 23, 2022 | Sale | $3.16 | 4,198 | 13,266 | 31,777 | Sep 26, 2022, 07:32 PM |
| Ajer Jeffrey Robert | Director | Sep 23, 2022 | Sale | $3.16 | 4,198 | 13,266 | 38,512 | Sep 26, 2022, 07:25 PM |
| CHESS ROBERT | Director | Sep 22, 2022 | Sale | $3.19 | 5,100 | 16,269 | 228,179 | Sep 26, 2022, 07:23 PM |
| EASTHAM KARIN | Director | Sep 13, 2022 | Sale | $3.61 | 21,267 | 76,774 | 13,033 | Sep 14, 2022, 06:01 PM |
| Zalevsky Jonathan | Chief R&D Officer | Aug 18, 2022 | Sale | $4.65 | 73,716 | 342,779 | 327,123 | Aug 19, 2022, 06:27 PM |
| Zalevsky Jonathan | Chief R&D Officer | Aug 16, 2022 | Sale | $4.76 | 10,560 | 50,266 | 400,839 | Aug 17, 2022, 07:41 PM |
| Wilson Mark Andrew | SVP & General Counsel | Aug 16, 2022 | Sale | $4.76 | 3,189 | 15,180 | 281,188 | Aug 17, 2022, 07:40 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2022 | Sale | $4.76 | 2,006 | 9,549 | 334,859 | Aug 17, 2022, 07:40 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2022 | Sale | $4.76 | 13,759 | 65,493 | 1,017,807 | Aug 17, 2022, 07:39 PM |
| Zalevsky Jonathan | Chief R&D Officer | May 16, 2022 | Sale | $3.95 | 21,673 | 85,608 | 276,399 | May 17, 2022, 09:40 PM |
| Wilson Mark Andrew | SVP & General Counsel | May 16, 2022 | Sale | $3.95 | 3,136 | 12,387 | 117,939 | May 17, 2022, 09:38 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 16, 2022 | Sale | $3.95 | 5,841 | 23,072 | 170,427 | May 17, 2022, 09:36 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2022 | Sale | $3.95 | 36,529 | 144,290 | 620,941 | May 17, 2022, 09:35 PM |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | May 16, 2022 | Sale | $3.95 | 4,592 | 18,138 | 223,210 | May 17, 2022, 09:33 PM |
| Labrucherie Gil M | SVP, COO & CFO | May 16, 2022 | Sale | $3.95 | 17,448 | 68,920 | 312,905 | May 17, 2022, 09:32 PM |
| Zalevsky Jonathan | Chief R&D Officer | Feb 16, 2022 | Sale | $10.95 | 10,912 | 119,486 | 274,122 | Feb 18, 2022, 06:20 PM |
| Wilson Mark Andrew | SVP & General Counsel | Feb 16, 2022 | Sale | $10.95 | 3,661 | 40,088 | 121,075 | Feb 18, 2022, 06:18 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 16, 2022 | Sale | $10.95 | 2,363 | 25,875 | 165,318 | Feb 18, 2022, 06:18 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2022 | Sale | $10.95 | 12,480 | 136,656 | 589,020 | Feb 18, 2022, 06:16 PM |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | Feb 16, 2022 | Sale | $10.95 | 4,852 | 53,129 | 227,802 | Feb 18, 2022, 06:15 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 16, 2022 | Sale | $10.95 | 7,579 | 82,990 | 301,603 | Feb 18, 2022, 06:14 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 18, 2021 | Sale | $12.69 | 3,000 | 38,070 | 256,682 | Nov 18, 2021, 06:06 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 16, 2021 | Sale | $13.16 | 21,149 | 278,321 | 259,682 | Nov 18, 2021, 06:06 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 16, 2021 | Sale | $13.16 | 20,869 | 274,636 | 232,084 | Nov 17, 2021, 06:11 PM |
| Wilson Mark Andrew | SVP & General Counsel | Nov 16, 2021 | Sale | $13.16 | 6,564 | 86,382 | 86,436 | Nov 17, 2021, 06:09 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 16, 2021 | Sale | $13.16 | 6,741 | 88,712 | 145,981 | Nov 17, 2021, 06:08 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2021 | Sale | $13.16 | 42,773 | 562,893 | 475,450 | Nov 17, 2021, 06:07 PM |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | Nov 16, 2021 | Sale | $13.16 | 6,061 | 79,763 | 194,854 | Nov 17, 2021, 06:06 PM |
| GREER R SCOTT | Director | Nov 09, 2021 | Option Exercise | $12.80 | 12,500 | 160,000 | 293,374 | Nov 09, 2021, 05:05 PM |
| Curet Myriam | Director | Sep 22, 2021 | Sale | $17.78 | 3,665 | 65,164 | 25,775 | Sep 24, 2021, 06:14 PM |
| CHESS ROBERT | Director | Sep 22, 2021 | Sale | $17.94 | 4,600 | 82,524 | 279,873 | Sep 24, 2021, 06:13 PM |
| Ajer Jeffrey Robert | Director | Sep 22, 2021 | Sale | $17.78 | 3,665 | 65,164 | 32,510 | Sep 24, 2021, 06:12 PM |
| WHITFIELD ROY A | Director | Sep 16, 2021 | Option Exercise | $13.80 | 40,000 | 552,000 | 225,850 | Sep 17, 2021, 06:44 PM |
| CHESS ROBERT | Director | Sep 09, 2021 | Option Exercise | $13.80 | 10,279 | 141,850 | 284,552 | Sep 10, 2021, 06:03 PM |
| CHESS ROBERT | Director | Sep 08, 2021 | Option Exercise | $13.80 | 8,000 | 110,400 | 282,273 | Sep 10, 2021, 06:03 PM |
| CHESS ROBERT | Director | Sep 09, 2021 | Sale | $16.02 | 10,279 | 164,670 | 274,273 | Sep 10, 2021, 06:03 PM |
| CHESS ROBERT | Director | Sep 08, 2021 | Sale | $16.00 | 8,000 | 128,000 | 274,273 | Sep 10, 2021, 06:03 PM |
| GREER R SCOTT | Director | Aug 31, 2021 | Option Exercise | $12.70 | 45,000 | 571,500 | 270,674 | Aug 31, 2021, 06:26 PM |
| Zalevsky Jonathan | Chief R&D Officer | Aug 16, 2021 | Sale | $13.83 | 7,662 | 105,965 | 212,803 | Aug 18, 2021, 07:04 PM |
| Wilson Mark Andrew | SVP & General Counsel | Aug 16, 2021 | Sale | $13.83 | 1,910 | 26,415 | 72,900 | Aug 18, 2021, 07:02 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2021 | Sale | $13.83 | 11,515 | 159,252 | 424,123 | Aug 18, 2021, 07:01 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2021 | Sale | $13.83 | 13,339 | 184,478 | 137,822 | Aug 18, 2021, 07:00 PM |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | Aug 16, 2021 | Sale | $13.83 | 6,192 | 85,635 | 200,915 | Aug 18, 2021, 06:59 PM |
| Labrucherie Gil M | SVP, COO & CFO | Aug 17, 2021 | Sale | $13.56 | 3,000 | 40,680 | 240,231 | Aug 18, 2021, 06:58 PM |
| Labrucherie Gil M | SVP, COO & CFO | Aug 16, 2021 | Sale | $13.83 | 7,867 | 108,801 | 243,231 | Aug 18, 2021, 06:58 PM |
| CHESS ROBERT | Director | Jul 20, 2021 | Option Exercise | $13.80 | 2,106 | 29,063 | 282,679 | Jul 22, 2021, 07:13 PM |
| CHESS ROBERT | Director | Jul 22, 2021 | Option Exercise | $13.80 | 91 | 1,256 | 280,664 | Jul 22, 2021, 07:13 PM |
| CHESS ROBERT | Director | Jul 21, 2021 | Option Exercise | $13.80 | 3,524 | 48,631 | 284,097 | Jul 22, 2021, 07:13 PM |
| CHESS ROBERT | Director | Jul 22, 2021 | Sale | $16.80 | 91 | 1,529 | 280,573 | Jul 22, 2021, 07:13 PM |
| CHESS ROBERT | Director | Jul 21, 2021 | Sale | $16.81 | 3,524 | 59,238 | 280,573 | Jul 22, 2021, 07:13 PM |
| CHESS ROBERT | Director | Jul 20, 2021 | Sale | $16.80 | 2,106 | 35,381 | 280,573 | Jul 22, 2021, 07:13 PM |
| Labrucherie Gil M | SVP, COO & CFO | May 17, 2021 | Sale | $18.30 | 7,898 | 144,533 | 251,098 | May 19, 2021, 07:04 PM |
| CHESS ROBERT | Director | May 12, 2021 | Option Exercise | $13.80 | 8,000 | 110,400 | 288,573 | May 14, 2021, 06:05 PM |
| CHESS ROBERT | Director | May 12, 2021 | Sale | $19.34 | 8,000 | 154,720 | 280,573 | May 14, 2021, 06:05 PM |
| CHESS ROBERT | Director | Apr 14, 2021 | Option Exercise | $13.80 | 8,000 | 110,400 | 288,573 | Apr 16, 2021, 06:02 PM |
| CHESS ROBERT | Director | Apr 14, 2021 | Sale | $18.98 | 8,000 | 151,840 | 280,573 | Apr 16, 2021, 06:02 PM |
| Zalevsky Jonathan | Chief R&D Officer | Feb 16, 2021 | Sale | $22.37 | 24,141 | 540,034 | 266,176 | Feb 18, 2021, 07:07 PM |
| Wilson Mark Andrew | SVP & General Counsel | Feb 16, 2021 | Sale | $22.37 | 2,173 | 48,610 | 76,727 | Feb 18, 2021, 07:06 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 16, 2021 | Sale | $22.37 | 11,705 | 261,841 | 164,552 | Feb 18, 2021, 07:05 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2021 | Sale | $22.37 | 11,495 | 257,143 | 447,198 | Feb 18, 2021, 07:04 PM |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | Feb 16, 2021 | Sale | $22.37 | 15,358 | 343,558 | 213,192 | Feb 18, 2021, 07:03 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 16, 2021 | Sale | $22.37 | 7,977 | 178,445 | 258,996 | Feb 18, 2021, 07:03 PM |
| Wilson Mark Andrew | SVP & General Counsel | Feb 03, 2021 | Option Exercise | $8.80 | 5,344 | 47,027 | 84,244 | Feb 04, 2021, 08:44 PM |
| Wilson Mark Andrew | SVP & General Counsel | Feb 03, 2021 | Sale | $19.45 | 5,344 | 103,941 | 78,900 | Feb 04, 2021, 08:44 PM |
| ROBIN HOWARD W | President & CEO | Feb 04, 2021 | Option Exercise | $8.80 | 150,000 | 1,320,000 | 608,693 | Feb 04, 2021, 08:43 PM |
| ROBIN HOWARD W | President & CEO | Feb 03, 2021 | Option Exercise | $8.80 | 150,000 | 1,320,000 | 608,693 | Feb 04, 2021, 08:43 PM |
| ROBIN HOWARD W | President & CEO | Feb 02, 2021 | Option Exercise | $8.80 | 150,000 | 1,320,000 | 608,693 | Feb 04, 2021, 08:43 PM |
| ROBIN HOWARD W | President & CEO | Feb 04, 2021 | Sale | $20.29 | 150,000 | 3,042,906 | 516,830 | Feb 04, 2021, 08:43 PM |
| ROBIN HOWARD W | President & CEO | Feb 03, 2021 | Sale | $19.72 | 150,000 | 2,958,000 | 458,693 | Feb 04, 2021, 08:43 PM |
| ROBIN HOWARD W | President & CEO | Feb 02, 2021 | Sale | $19.77 | 150,000 | 2,966,025 | 469,193 | Feb 04, 2021, 08:43 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 04, 2021 | Option Exercise | $8.80 | 50,000 | 440,000 | 316,973 | Feb 04, 2021, 08:42 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 03, 2021 | Option Exercise | $8.80 | 50,000 | 440,000 | 316,973 | Feb 04, 2021, 08:42 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 02, 2021 | Option Exercise | $8.80 | 50,000 | 440,000 | 316,973 | Feb 04, 2021, 08:42 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 04, 2021 | Sale | $19.81 | 50,000 | 990,500 | 266,973 | Feb 04, 2021, 08:42 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 03, 2021 | Sale | $19.61 | 50,000 | 980,500 | 266,973 | Feb 04, 2021, 08:42 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 02, 2021 | Sale | $20.17 | 50,000 | 1,008,629 | 275,838 | Feb 04, 2021, 08:42 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jan 28, 2021 | Option Exercise | $8.80 | 75,000 | 660,000 | 251,257 | Jan 29, 2021, 06:10 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jan 28, 2021 | Sale | $18.62 | 75,000 | 1,396,500 | 176,257 | Jan 29, 2021, 06:10 PM |
| GREER R SCOTT | Director | Jan 05, 2021 | Option Exercise | $13.80 | 40,000 | 552,000 | 225,674 | Jan 05, 2021, 05:09 PM |
| Myriam Curet | Director | Dec 15, 2020 | Sale | $17.82 | 1,560 | 27,799 | 19,240 | Dec 17, 2020, 06:08 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 23, 2020 | Sale | $16.40 | 16,380 | 268,632 | 250,317 | Nov 25, 2020, 06:09 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 16, 2020 | Sale | $16.93 | 29,618 | 501,433 | 266,697 | Nov 18, 2020, 07:08 PM |
| Wilson Mark Andrew | SVP & General Counsel | Nov 16, 2020 | Sale | $16.93 | 1,539 | 26,055 | 49,850 | Nov 18, 2020, 07:07 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 16, 2020 | Sale | $16.93 | 11,976 | 202,754 | 159,757 | Nov 18, 2020, 07:05 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2020 | Sale | $16.93 | 11,975 | 202,737 | 352,043 | Nov 18, 2020, 07:04 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 16, 2020 | Sale | $16.93 | 8,276 | 140,113 | 226,973 | Nov 18, 2020, 07:03 PM |
| Ajer Jeffrey Robert | Director | Sep 28, 2020 | Sale | $17.25 | 3,250 | 56,063 | 25,975 | Sep 30, 2020, 07:03 PM |
| CHESS ROBERT | Director | Sep 25, 2020 | Sale | $17.75 | 5,500 | 97,625 | 280,573 | Sep 25, 2020, 08:16 PM |
| Labrucherie Gil M | SVP, COO & CFO | Sep 17, 2020 | Sale | $19.96 | 2,000 | 39,920 | 235,249 | Sep 21, 2020, 08:59 PM |
| Ajer Jeffrey Robert | Director | Sep 21, 2020 | Sale | $19.74 | 2,250 | 44,415 | 20,125 | Sep 21, 2020, 08:58 PM |
| CHESS ROBERT | Director | Sep 08, 2020 | Option Exercise | $9.24 | 8,000 | 73,920 | 284,973 | Sep 10, 2020, 08:19 PM |
| CHESS ROBERT | Director | Sep 08, 2020 | Sale | $18.53 | 8,000 | 148,240 | 276,973 | Sep 10, 2020, 08:19 PM |
| WHITFIELD ROY A | Director | Sep 04, 2020 | Option Exercise | $9.24 | 30,000 | 277,200 | 228,250 | Sep 08, 2020, 06:18 PM |
| Zalevsky Jonathan | Chief R&D Officer | Aug 17, 2020 | Sale | $19.67 | 26,200 | 515,354 | 296,315 | Aug 19, 2020, 06:41 PM |
| Wilson Mark Andrew | SVP & General Counsel | Aug 17, 2020 | Sale | $19.67 | 1,529 | 30,075 | 51,389 | Aug 19, 2020, 06:40 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 17, 2020 | Sale | $19.67 | 1,367 | 26,889 | 171,733 | Aug 19, 2020, 06:39 PM |
| ROBIN HOWARD W | President & CEO | Aug 17, 2020 | Sale | $19.67 | 11,885 | 233,778 | 364,018 | Aug 19, 2020, 06:38 PM |
| Labrucherie Gil M | SVP, COO & CFO | Aug 18, 2020 | Sale | $19.68 | 2,000 | 39,360 | 237,249 | Aug 19, 2020, 06:37 PM |
| Labrucherie Gil M | SVP, COO & CFO | Aug 17, 2020 | Sale | $19.67 | 6,245 | 122,839 | 239,249 | Aug 19, 2020, 06:37 PM |
| GREER R SCOTT | Director | Jul 09, 2020 | Option Exercise | $9.24 | 40,000 | 369,600 | 191,583 | Jul 10, 2020, 07:06 PM |
| GREER R SCOTT | Director | Jul 09, 2020 | Sale | $25.00 | 15,009 | 375,225 | 176,574 | Jul 10, 2020, 07:06 PM |
| CHESS ROBERT | Director | Jul 08, 2020 | Option Exercise | $9.24 | 8,000 | 73,920 | 284,973 | Jul 10, 2020, 07:05 PM |
| CHESS ROBERT | Director | Jul 08, 2020 | Sale | $24.58 | 8,000 | 196,640 | 276,973 | Jul 10, 2020, 07:05 PM |
| Zalevsky Jonathan | Chief R&D Officer | May 18, 2020 | Sale | $22.51 | 4,558 | 102,601 | 322,515 | May 20, 2020, 06:33 PM |
| Wilson Mark Andrew | SVP & General Counsel | May 18, 2020 | Sale | $22.51 | 1,529 | 34,418 | 52,418 | May 20, 2020, 06:32 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 18, 2020 | Sale | $22.51 | 1,367 | 30,771 | 172,719 | May 20, 2020, 06:31 PM |
| ROBIN HOWARD W | President & CEO | May 18, 2020 | Sale | $22.51 | 8,968 | 201,870 | 375,903 | May 20, 2020, 06:30 PM |
| Labrucherie Gil M | SVP, COO & CFO | May 18, 2020 | Sale | $22.51 | 5,727 | 128,915 | 247,494 | May 20, 2020, 06:29 PM |
| Labrucherie Gil M | SVP, COO & CFO | May 19, 2020 | Sale | $22.62 | 2,000 | 45,240 | 245,494 | May 20, 2020, 06:29 PM |
| CHESS ROBERT | Director | Apr 15, 2020 | Option Exercise | $9.24 | 8,000 | 73,920 | 284,973 | Apr 17, 2020, 06:03 PM |
| CHESS ROBERT | Director | Apr 15, 2020 | Sale | $18.38 | 8,000 | 147,010 | 277,170 | Apr 17, 2020, 06:03 PM |
| CHESS ROBERT | Director | Mar 11, 2020 | Option Exercise | $9.24 | 8,000 | 73,920 | 284,973 | Mar 13, 2020, 06:04 PM |
| CHESS ROBERT | Director | Mar 11, 2020 | Sale | $16.79 | 8,000 | 134,316 | 278,173 | Mar 13, 2020, 06:04 PM |
| Zalevsky Jonathan | Chief R&D Officer | Feb 18, 2020 | Sale | $22.35 | 4,774 | 106,699 | 327,073 | Feb 20, 2020, 06:39 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 18, 2020 | Sale | $22.35 | 1,394 | 31,156 | 174,086 | Feb 20, 2020, 06:39 PM |
| ROBIN HOWARD W | President & CEO | Feb 18, 2020 | Sale | $22.35 | 8,448 | 188,813 | 384,871 | Feb 20, 2020, 06:38 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 18, 2020 | Sale | $22.35 | 5,938 | 132,714 | 253,221 | Feb 20, 2020, 06:37 PM |
| CHESS ROBERT | Director | Feb 12, 2020 | Option Exercise | $9.24 | 8,000 | 73,920 | 284,973 | Feb 14, 2020, 07:00 PM |
| CHESS ROBERT | Director | Feb 12, 2020 | Sale | $23.50 | 8,000 | 188,000 | 280,572 | Feb 14, 2020, 07:00 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 06, 2020 | Option Exercise | $7.21 | 37,500 | 270,375 | 212,980 | Feb 07, 2020, 07:31 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 06, 2020 | Sale | $22.78 | 37,500 | 854,250 | 175,480 | Feb 07, 2020, 07:31 PM |
| WHITFIELD ROY A | Director | Dec 18, 2019 | Option Exercise | $9.24 | 10,000 | 92,400 | 198,250 | Dec 20, 2019, 06:31 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 18, 2019 | Sale | $17.97 | 3,960 | 71,161 | 291,697 | Nov 20, 2019, 07:07 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 18, 2019 | Sale | $17.97 | 2,713 | 48,753 | 160,441 | Nov 20, 2019, 07:06 PM |
| ROBIN HOWARD W | President & CEO | Nov 18, 2019 | Sale | $17.97 | 13,556 | 243,601 | 299,219 | Nov 20, 2019, 07:05 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 18, 2019 | Sale | $17.97 | 8,863 | 159,268 | 219,009 | Nov 20, 2019, 07:04 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 13, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 252,872 | Nov 15, 2019, 06:09 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 13, 2019 | Sale | $19.79 | 25,000 | 494,750 | 227,872 | Nov 15, 2019, 06:09 PM |
| ROBIN HOWARD W | President & CEO | Oct 15, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 346,108 | Oct 17, 2019, 07:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 17, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 346,108 | Oct 17, 2019, 07:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 16, 2019 | Option Exercise | $7.21 | 33,334 | 240,338 | 346,109 | Oct 17, 2019, 07:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 15, 2019 | Sale | $16.95 | 33,333 | 565,085 | 337,275 | Oct 17, 2019, 07:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 17, 2019 | Sale | $17.68 | 33,333 | 589,327 | 312,775 | Oct 17, 2019, 07:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 16, 2019 | Sale | $17.48 | 33,334 | 582,678 | 312,775 | Oct 17, 2019, 07:00 PM |
| Labrucherie Gil M | SVP, COO & CFO | Oct 15, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 252,872 | Oct 17, 2019, 06:59 PM |
| Labrucherie Gil M | SVP, COO & CFO | Oct 15, 2019 | Sale | $15.83 | 25,000 | 395,750 | 227,872 | Oct 17, 2019, 06:59 PM |
| Lingnau Lutz | Director | Sep 27, 2019 | Sale | $17.84 | 3,000 | 53,520 | 26,700 | Oct 02, 2019, 07:51 PM |
| Ajer Jeffrey Robert | Director | Sep 30, 2019 | Sale | $18.06 | 2,375 | 42,892 | 22,375 | Oct 01, 2019, 07:16 PM |
| CHESS ROBERT | Director | Sep 27, 2019 | Sale | $17.99 | 4,000 | 71,960 | 276,973 | Oct 01, 2019, 07:15 PM |
| Ajer Jeffrey Robert | Director | Sep 20, 2019 | Sale | $20.24 | 2,250 | 45,540 | 18,250 | Sep 24, 2019, 06:07 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Sep 16, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 177,872 | Sep 18, 2019, 07:07 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Sep 16, 2019 | Sale | $20.52 | 25,000 | 513,000 | 152,872 | Sep 18, 2019, 07:07 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Sep 05, 2019 | Buy | $17.28 | 15,000 | 259,200 | 107,668 | Sep 09, 2019, 05:09 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 26, 2019 | Option Exercise | $16.31 | 30,000 | 489,300 | 152,872 | Aug 27, 2019, 05:20 PM |
| ROBIN HOWARD W | President & CEO | Aug 23, 2019 | Option Exercise | $16.31 | 30,000 | 489,300 | 312,775 | Aug 26, 2019, 05:21 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2019 | Sale | $18.15 | 1,809 | 32,833 | 163,154 | Aug 19, 2019, 07:09 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2019 | Sale | $18.15 | 12,551 | 227,801 | 282,775 | Aug 19, 2019, 07:08 PM |
| Nicholson John | SVP & Chief Operating Officer | Aug 16, 2019 | Sale | $18.15 | 3,819 | 69,315 | 162,759 | Aug 19, 2019, 07:07 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 16, 2019 | Sale | $18.15 | 5,063 | 91,893 | 122,872 | Aug 19, 2019, 07:07 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Aug 16, 2019 | Sale | $18.15 | 3,245 | 58,897 | 92,668 | Aug 19, 2019, 07:06 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 14, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 152,935 | Aug 16, 2019, 08:13 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 14, 2019 | Sale | $17.79 | 25,000 | 444,750 | 127,935 | Aug 16, 2019, 08:13 PM |
| ROBIN HOWARD W | President & CEO | Jul 24, 2019 | Option Exercise | $7.21 | 33,334 | 240,338 | 328,660 | Jul 25, 2019, 08:02 PM |
| ROBIN HOWARD W | President & CEO | Jul 23, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 328,659 | Jul 25, 2019, 08:02 PM |
| ROBIN HOWARD W | President & CEO | Jul 25, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 328,659 | Jul 25, 2019, 08:02 PM |
| ROBIN HOWARD W | President & CEO | Jul 24, 2019 | Sale | $32.11 | 33,334 | 1,070,355 | 295,326 | Jul 25, 2019, 08:02 PM |
| ROBIN HOWARD W | President & CEO | Jul 23, 2019 | Sale | $32.10 | 33,333 | 1,069,989 | 295,326 | Jul 25, 2019, 08:02 PM |
| ROBIN HOWARD W | President & CEO | Jul 25, 2019 | Sale | $29.65 | 33,333 | 988,323 | 295,326 | Jul 25, 2019, 08:02 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Jul 10, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 152,935 | Jul 12, 2019, 06:31 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Jul 10, 2019 | Sale | $34.57 | 25,000 | 864,250 | 127,935 | Jul 12, 2019, 06:31 PM |
| Lingnau Lutz | Director | Jul 08, 2019 | Option Exercise | $9.24 | 10,000 | 92,400 | 33,200 | Jul 10, 2019, 05:34 PM |
| Lingnau Lutz | Director | Jul 08, 2019 | Sale | $34.63 | 10,000 | 346,300 | 23,200 | Jul 10, 2019, 05:34 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Jun 17, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 152,935 | Jun 19, 2019, 05:50 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Jun 17, 2019 | Sale | $33.71 | 25,000 | 842,750 | 127,935 | Jun 19, 2019, 05:50 PM |
| ROBIN HOWARD W | President & CEO | May 22, 2019 | Option Exercise | $7.21 | 33,334 | 240,338 | 328,660 | May 23, 2019, 07:19 PM |
| ROBIN HOWARD W | President & CEO | May 21, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 328,659 | May 23, 2019, 07:19 PM |
| ROBIN HOWARD W | President & CEO | May 23, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 328,659 | May 23, 2019, 07:19 PM |
| ROBIN HOWARD W | President & CEO | May 22, 2019 | Sale | $33.38 | 33,334 | 1,112,689 | 295,326 | May 23, 2019, 07:19 PM |
| ROBIN HOWARD W | President & CEO | May 21, 2019 | Sale | $32.93 | 33,333 | 1,097,656 | 295,326 | May 23, 2019, 07:19 PM |
| ROBIN HOWARD W | President & CEO | May 23, 2019 | Sale | $32.69 | 33,333 | 1,089,656 | 295,326 | May 23, 2019, 07:19 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 16, 2019 | Sale | $31.37 | 1,928 | 60,481 | 164,463 | May 17, 2019, 08:22 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2019 | Sale | $31.37 | 13,383 | 419,825 | 295,326 | May 17, 2019, 08:22 PM |
| Nicholson John | SVP & Chief Operating Officer | May 16, 2019 | Sale | $31.37 | 4,077 | 127,895 | 166,578 | May 17, 2019, 08:21 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 16, 2019 | Sale | $31.37 | 3,767 | 118,171 | 127,935 | May 17, 2019, 08:20 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | May 16, 2019 | Sale | $31.37 | 2,449 | 76,825 | 94,694 | May 17, 2019, 08:19 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | May 16, 2019 | Sale | $31.37 | 3,461 | 108,572 | 95,913 | May 17, 2019, 08:18 PM |
| GREER R SCOTT | Director | Mar 08, 2019 | Option Exercise | $5.14 | 10,000 | 51,400 | 145,083 | Mar 12, 2019, 06:18 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 19, 2019 | Sale | $42.39 | 1,808 | 76,641 | 166,391 | Feb 21, 2019, 08:17 PM |
| ROBIN HOWARD W | President & CEO | Feb 20, 2019 | Option Exercise | $7.21 | 33,334 | 240,338 | 342,043 | Feb 21, 2019, 08:16 PM |
| ROBIN HOWARD W | President & CEO | Feb 19, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 350,924 | Feb 21, 2019, 08:16 PM |
| ROBIN HOWARD W | President & CEO | Feb 21, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 342,042 | Feb 21, 2019, 08:16 PM |
| ROBIN HOWARD W | President & CEO | Feb 20, 2019 | Sale | $43.20 | 33,334 | 1,440,029 | 308,709 | Feb 21, 2019, 08:16 PM |
| ROBIN HOWARD W | President & CEO | Feb 19, 2019 | Sale | $42.33 | 42,215 | 1,787,161 | 317,591 | Feb 21, 2019, 08:16 PM |
| ROBIN HOWARD W | President & CEO | Feb 21, 2019 | Sale | $41.01 | 33,333 | 1,366,986 | 308,709 | Feb 21, 2019, 08:16 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 19, 2019 | Sale | $42.39 | 3,822 | 162,015 | 170,655 | Feb 21, 2019, 08:15 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Feb 19, 2019 | Sale | $42.39 | 3,592 | 152,265 | 131,702 | Feb 21, 2019, 08:14 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Feb 19, 2019 | Sale | $42.39 | 2,386 | 101,143 | 97,143 | Feb 21, 2019, 08:13 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Feb 19, 2019 | Sale | $42.39 | 3,310 | 140,311 | 99,374 | Feb 21, 2019, 08:13 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 04, 2019 | Option Exercise | $10.69 | 16,119 | 172,312 | 184,318 | Feb 06, 2019, 07:17 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 04, 2019 | Sale | $42.16 | 16,119 | 679,577 | 168,199 | Feb 06, 2019, 07:17 PM |
| Nicholson John | SVP & Chief Operating Officer | Jan 28, 2019 | Option Exercise | $10.69 | 63,000 | 673,470 | 237,477 | Jan 30, 2019, 06:02 PM |
| Nicholson John | SVP & Chief Operating Officer | Jan 28, 2019 | Sale | $42.82 | 63,000 | 2,697,660 | 174,477 | Jan 30, 2019, 06:02 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 16, 2018 | Sale | $38.25 | 4,016 | 153,612 | 157,249 | Nov 19, 2018, 06:15 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2018 | Sale | $38.25 | 15,326 | 586,220 | 249,141 | Nov 19, 2018, 06:14 PM |
| Nicholson John | SVP & Chief Operating Officer | Nov 16, 2018 | Sale | $38.25 | 5,982 | 228,812 | 174,477 | Nov 19, 2018, 06:14 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Nov 16, 2018 | Sale | $38.25 | 6,515 | 249,199 | 106,544 | Nov 19, 2018, 06:13 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 16, 2018 | Sale | $38.25 | 4,694 | 179,546 | 81,029 | Nov 19, 2018, 06:12 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 16, 2018 | Sale | $38.25 | 4,524 | 173,043 | 78,734 | Nov 19, 2018, 06:11 PM |
| Lingnau Lutz | Director | Sep 20, 2018 | Sale | $56.98 | 9,000 | 512,820 | 18,450 | Sep 21, 2018, 07:32 PM |
| CHESS ROBERT | Director | Sep 19, 2018 | Sale | $56.81 | 4,500 | 255,645 | 269,723 | Sep 21, 2018, 07:31 PM |
| Ajer Jeffrey Robert | Director | Sep 20, 2018 | Sale | $56.76 | 6,750 | 383,130 | 15,750 | Sep 21, 2018, 07:29 PM |
| GREER R SCOTT | Director | Sep 04, 2018 | Option Exercise | $5.14 | 10,000 | 51,400 | 140,333 | Sep 06, 2018, 07:12 PM |
| GREER R SCOTT | Director | Sep 04, 2018 | Sale | $67.39 | 10,000 | 673,900 | 130,333 | Sep 06, 2018, 07:12 PM |
| WINGER DENNIS L | Director | Aug 17, 2018 | Option Exercise | $14.26 | 15,000 | 213,900 | 57,750 | Aug 21, 2018, 07:32 PM |
| WINGER DENNIS L | Director | Aug 21, 2018 | Option Exercise | $14.26 | 15,000 | 213,900 | 57,750 | Aug 21, 2018, 07:32 PM |
| WINGER DENNIS L | Director | Aug 21, 2018 | Sale | $60.30 | 15,000 | 904,500 | 42,750 | Aug 21, 2018, 07:32 PM |
| WINGER DENNIS L | Director | Aug 17, 2018 | Sale | $59.62 | 15,000 | 894,300 | 42,750 | Aug 21, 2018, 07:32 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2018 | Option Exercise | $58.40 | 4,883 | 285,167 | 71,265 | Aug 16, 2018, 09:47 PM |
| Nicholson John | SVP & Chief Operating Officer | Aug 16, 2018 | Option Exercise | $58.40 | 8,137 | 475,201 | 180,459 | Aug 16, 2018, 09:46 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 16, 2018 | Option Exercise | $58.40 | 8,207 | 479,289 | 113,059 | Aug 16, 2018, 09:45 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Aug 16, 2018 | Option Exercise | $58.40 | 5,946 | 347,246 | 85,723 | Aug 16, 2018, 09:44 PM |
| ROBIN HOWARD W | President & CEO | Aug 14, 2018 | Option Exercise | $10.69 | 40,000 | 427,600 | 264,356 | Aug 16, 2018, 09:44 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2018 | Option Exercise | $58.40 | 20,389 | 1,190,718 | 264,467 | Aug 16, 2018, 09:44 PM |
| ROBIN HOWARD W | President & CEO | Aug 14, 2018 | Option Exercise | $60.08 | 40,000 | 2,403,200 | 224,356 | Aug 16, 2018, 09:44 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Aug 16, 2018 | Option Exercise | $58.40 | 6,701 | 391,338 | 83,258 | Aug 16, 2018, 09:43 PM |
| WINGER DENNIS L | Director | Aug 14, 2018 | Sale | $60.15 | 17,125 | 1,030,069 | 42,750 | Aug 15, 2018, 07:30 PM |
| WINGER DENNIS L | Director | Aug 13, 2018 | Sale | $61.04 | 17,125 | 1,045,310 | 59,875 | Aug 15, 2018, 07:30 PM |
| ROBIN HOWARD W | President & CEO | Jun 27, 2018 | Option Exercise | $10.69 | 43,333 | 463,230 | 267,689 | Jun 27, 2018, 07:42 PM |
| ROBIN HOWARD W | President & CEO | Jun 26, 2018 | Option Exercise | $10.69 | 43,333 | 463,230 | 267,689 | Jun 27, 2018, 07:42 PM |
| ROBIN HOWARD W | President & CEO | Jun 25, 2018 | Option Exercise | $10.69 | 43,334 | 463,240 | 267,690 | Jun 27, 2018, 07:42 PM |
| ROBIN HOWARD W | President & CEO | Jun 26, 2018 | Sale | $49.36 | 43,333 | 2,138,917 | 224,356 | Jun 27, 2018, 07:42 PM |
| ROBIN HOWARD W | President & CEO | Jun 25, 2018 | Sale | $51.82 | 43,334 | 2,245,568 | 224,356 | Jun 27, 2018, 07:42 PM |
| ROBIN HOWARD W | President & CEO | Jun 27, 2018 | Sale | $47.39 | 43,333 | 2,053,551 | 224,356 | Jun 27, 2018, 07:42 PM |
| WHITFIELD ROY A | Director | Jun 06, 2018 | Buy | $59.37 | 3,400 | 201,860 | 177,000 | Jun 07, 2018, 07:40 PM |
| WHITFIELD ROY A | Director | Jun 05, 2018 | Buy | $55.22 | 1,600 | 88,352 | 173,600 | Jun 07, 2018, 07:40 PM |
| CHESS ROBERT | Director | Jun 05, 2018 | Option Exercise | $14.26 | 10,000 | 142,600 | 284,223 | Jun 07, 2018, 07:39 PM |
| CHESS ROBERT | Director | Jun 05, 2018 | Sale | $55.16 | 10,000 | 551,600 | 274,223 | Jun 07, 2018, 07:39 PM |
| GREER R SCOTT | Director | Jun 06, 2018 | Option Exercise | $5.14 | 8,600 | 44,204 | 138,933 | Jun 06, 2018, 07:42 PM |
| GREER R SCOTT | Director | Jun 04, 2018 | Option Exercise | $5.14 | 1,400 | 7,196 | 131,733 | Jun 06, 2018, 07:42 PM |
| GREER R SCOTT | Director | Jun 06, 2018 | Sale | $60.00 | 8,600 | 516,000 | 130,333 | Jun 06, 2018, 07:42 PM |
| GREER R SCOTT | Director | Jun 04, 2018 | Sale | $61.99 | 1,400 | 86,786 | 130,333 | Jun 06, 2018, 07:42 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 16, 2018 | Sale | $83.39 | 3,576 | 298,203 | 65,281 | May 18, 2018, 07:07 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2018 | Sale | $83.39 | 12,791 | 1,066,641 | 224,356 | May 18, 2018, 07:06 PM |
| Nicholson John | SVP & Chief Operating Officer | May 16, 2018 | Sale | $83.39 | 4,917 | 410,029 | 162,596 | May 18, 2018, 07:05 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 16, 2018 | Sale | $83.39 | 4,941 | 412,030 | 94,798 | May 18, 2018, 07:03 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | May 16, 2018 | Sale | $83.39 | 4,060 | 338,563 | 76,201 | May 18, 2018, 07:02 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | May 16, 2018 | Sale | $83.39 | 3,435 | 286,445 | 63,959 | May 18, 2018, 07:01 PM |
| CHESS ROBERT | Director | May 03, 2018 | Option Exercise | $8.79 | 25,000 | 219,700 | 289,223 | May 04, 2018, 06:55 PM |
| CHESS ROBERT | Director | May 03, 2018 | Sale | $82.80 | 25,000 | 2,070,050 | 274,223 | May 04, 2018, 06:55 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 03, 2018 | Option Exercise | $10.69 | 30,000 | 320,700 | 129,739 | May 03, 2018, 08:43 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 02, 2018 | Option Exercise | $10.69 | 30,000 | 320,700 | 129,739 | May 03, 2018, 08:43 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 01, 2018 | Option Exercise | $10.69 | 30,000 | 320,700 | 129,739 | May 03, 2018, 08:43 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 03, 2018 | Sale | $82.86 | 30,000 | 2,485,800 | 99,739 | May 03, 2018, 08:43 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 02, 2018 | Sale | $85.63 | 30,000 | 2,568,900 | 99,739 | May 03, 2018, 08:43 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 01, 2018 | Sale | $83.65 | 30,000 | 2,509,500 | 99,739 | May 03, 2018, 08:43 PM |
| ROBIN HOWARD W | President & CEO | May 03, 2018 | Option Exercise | $10.69 | 43,333 | 463,230 | 280,480 | May 03, 2018, 08:42 PM |
| ROBIN HOWARD W | President & CEO | May 02, 2018 | Option Exercise | $10.69 | 43,333 | 463,230 | 280,480 | May 03, 2018, 08:42 PM |
| ROBIN HOWARD W | President & CEO | May 01, 2018 | Option Exercise | $10.69 | 43,334 | 463,240 | 280,481 | May 03, 2018, 08:42 PM |
| ROBIN HOWARD W | President & CEO | May 03, 2018 | Sale | $82.86 | 43,333 | 3,590,572 | 237,147 | May 03, 2018, 08:42 PM |
| ROBIN HOWARD W | President & CEO | May 02, 2018 | Sale | $85.63 | 43,333 | 3,710,605 | 237,147 | May 03, 2018, 08:42 PM |
| ROBIN HOWARD W | President & CEO | May 01, 2018 | Sale | $83.65 | 43,334 | 3,624,889 | 237,147 | May 03, 2018, 08:42 PM |
| WHITFIELD ROY A | Director | Apr 17, 2018 | Option Exercise | $14.26 | 30,000 | 427,800 | 172,000 | Apr 18, 2018, 06:05 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Apr 16, 2018 | Option Exercise | $10.69 | 13,881 | 148,388 | 82,738 | Apr 18, 2018, 06:03 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Apr 16, 2018 | Sale | $101.46 | 13,881 | 1,408,366 | 68,857 | Apr 18, 2018, 06:03 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 10, 2018 | Option Exercise | $7.21 | 502 | 3,619 | 80,763 | Apr 12, 2018, 06:05 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 10, 2018 | Sale | $105.67 | 502 | 53,046 | 80,261 | Apr 12, 2018, 06:05 PM |
| Lingnau Lutz | Director | Apr 05, 2018 | Option Exercise | $9.24 | 30,000 | 277,200 | 57,450 | Apr 09, 2018, 08:23 PM |
| Lingnau Lutz | Director | Apr 05, 2018 | Sale | $101.74 | 30,000 | 3,052,200 | 27,450 | Apr 09, 2018, 08:23 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 09, 2018 | Option Exercise | $7.21 | 9,498 | 68,481 | 89,759 | Apr 09, 2018, 08:22 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 05, 2018 | Option Exercise | $7.21 | 20,000 | 144,200 | 100,261 | Apr 09, 2018, 08:22 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 09, 2018 | Sale | $105.05 | 9,498 | 997,765 | 80,261 | Apr 09, 2018, 08:22 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 05, 2018 | Sale | $101.75 | 20,000 | 2,035,000 | 80,261 | Apr 09, 2018, 08:22 PM |
| GREER R SCOTT | Director | Apr 06, 2018 | Option Exercise | $14.26 | 30,000 | 427,800 | 160,333 | Apr 09, 2018, 08:22 PM |
| GREER R SCOTT | Director | Apr 06, 2018 | Sale | $92.22 | 30,000 | 2,766,600 | 130,333 | Apr 09, 2018, 08:22 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 09, 2018 | Option Exercise | $7.21 | 49,500 | 356,895 | 116,894 | Apr 09, 2018, 08:21 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 06, 2018 | Option Exercise | $9.10 | 110,500 | 1,005,505 | 177,894 | Apr 09, 2018, 08:21 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 09, 2018 | Sale | $96.13 | 49,500 | 4,758,435 | 67,394 | Apr 09, 2018, 08:21 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 06, 2018 | Sale | $91.69 | 110,500 | 10,131,745 | 67,394 | Apr 09, 2018, 08:21 PM |
| CHESS ROBERT | Director | Apr 06, 2018 | Option Exercise | $8.79 | 25,000 | 219,700 | 289,223 | Apr 09, 2018, 08:20 PM |
| CHESS ROBERT | Director | Apr 06, 2018 | Sale | $92.14 | 25,000 | 2,303,600 | 274,223 | Apr 09, 2018, 08:20 PM |
| KUEBLER CHRISTOPHER A | Director | Mar 07, 2018 | Option Exercise | $6.24 | 37,400 | 233,236 | 77,900 | Mar 08, 2018, 06:10 PM |
| KUEBLER CHRISTOPHER A | Director | Mar 06, 2018 | Option Exercise | $5.14 | 2,600 | 13,364 | 43,100 | Mar 08, 2018, 06:10 PM |
| KUEBLER CHRISTOPHER A | Director | Mar 07, 2018 | Sale | $97.41 | 37,400 | 3,643,134 | 40,500 | Mar 08, 2018, 06:10 PM |
| KUEBLER CHRISTOPHER A | Director | Mar 06, 2018 | Sale | $100.30 | 2,600 | 260,780 | 40,500 | Mar 08, 2018, 06:10 PM |
| Nicholson John | SVP & Chief Operating Officer | Mar 07, 2018 | Sale | $100.45 | 100,144 | 10,059,464 | 167,513 | Mar 08, 2018, 06:09 PM |
| Nicholson John | SVP & Chief Operating Officer | Mar 06, 2018 | Sale | $98.29 | 120,000 | 11,794,800 | 267,657 | Mar 08, 2018, 06:09 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 16, 2018 | Sale | $82.94 | 2,545 | 211,082 | 68,857 | Feb 20, 2018, 07:10 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2018 | Sale | $82.94 | 12,788 | 1,060,637 | 237,147 | Feb 20, 2018, 07:10 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 16, 2018 | Sale | $82.94 | 4,879 | 404,664 | 387,657 | Feb 20, 2018, 07:09 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Feb 16, 2018 | Sale | $82.94 | 3,477 | 288,382 | 99,739 | Feb 20, 2018, 07:08 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Feb 16, 2018 | Sale | $82.94 | 2,875 | 238,453 | 80,261 | Feb 20, 2018, 07:07 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Feb 16, 2018 | Sale | $82.94 | 2,426 | 201,212 | 67,394 | Feb 20, 2018, 07:07 PM |
| Nicholson John | SVP & Chief Operating Officer | Jan 31, 2018 | Option Exercise | $11.34 | 120,000 | 1,360,800 | 392,536 | Feb 02, 2018, 06:03 PM |
| ROBIN HOWARD W | President & CEO | Jan 22, 2018 | Option Exercise | $11.34 | 83,333 | 944,996 | 333,268 | Jan 24, 2018, 06:01 PM |
| ROBIN HOWARD W | President & CEO | Jan 22, 2018 | Sale | $75.82 | 83,333 | 6,318,308 | 249,935 | Jan 24, 2018, 06:01 PM |
| WINGER DENNIS L | Director | Jan 04, 2018 | Option Exercise | $11.97 | 33,750 | 403,988 | 77,000 | Jan 08, 2018, 06:07 PM |
| KUEBLER CHRISTOPHER A | Director | Jan 02, 2018 | Option Exercise | $14.26 | 30,000 | 427,800 | 70,500 | Jan 04, 2018, 06:01 PM |
| KUEBLER CHRISTOPHER A | Director | Jan 02, 2018 | Sale | $58.66 | 30,000 | 1,759,800 | 40,500 | Jan 04, 2018, 06:01 PM |
| ROBIN HOWARD W | President & CEO | Dec 13, 2017 | Option Exercise | $11.34 | 83,333 | 944,996 | 272,768 | Dec 15, 2017, 06:00 PM |
| ROBIN HOWARD W | President & CEO | Dec 13, 2017 | Sale | $55.69 | 83,333 | 4,640,815 | 189,435 | Dec 15, 2017, 06:00 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 16, 2017 | Option Exercise | $44.23 | 5,289 | 233,932 | 60,549 | Nov 17, 2017, 06:06 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2017 | Option Exercise | $44.23 | 18,069 | 799,192 | 189,435 | Nov 17, 2017, 06:06 PM |
| Nicholson John | SVP & Chief Operating Officer | Nov 16, 2017 | Option Exercise | $44.23 | 6,620 | 292,803 | 246,536 | Nov 17, 2017, 06:05 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Nov 16, 2017 | Option Exercise | $44.23 | 6,698 | 296,253 | 76,716 | Nov 17, 2017, 06:05 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 16, 2017 | Option Exercise | $44.23 | 5,597 | 247,555 | 67,636 | Nov 17, 2017, 06:04 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Nov 16, 2017 | Option Exercise | $44.23 | 5,022 | 222,123 | 56,553 | Nov 17, 2017, 06:03 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 16, 2017 | Option Exercise | $44.23 | 4,782 | 211,508 | 43,820 | Nov 17, 2017, 06:03 PM |
| Nicholson John | SVP & Chief Operating Officer | Nov 13, 2017 | Option Exercise | $9.24 | 25,000 | 231,000 | 249,066 | Nov 15, 2017, 06:02 PM |
| Nicholson John | SVP & Chief Operating Officer | Nov 13, 2017 | Sale | $37.78 | 15,910 | 601,080 | 233,156 | Nov 15, 2017, 06:02 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 07, 2017 | Option Exercise | $18.10 | 34,600 | 626,260 | 75,533 | Nov 08, 2017, 06:02 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 06, 2017 | Option Exercise | $10.69 | 5,117 | 54,701 | 63,350 | Nov 08, 2017, 06:02 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 06, 2017 | Sale | $25.07 | 5,117 | 128,283 | 58,233 | Nov 08, 2017, 06:02 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 07, 2017 | Option Exercise | $9.53 | 75,409 | 718,648 | 106,511 | Nov 08, 2017, 06:01 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 06, 2017 | Option Exercise | $9.53 | 20,914 | 199,310 | 52,016 | Nov 08, 2017, 06:01 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 08, 2017 | Option Exercise | $9.53 | 300,000 | 2,859,000 | 331,102 | Nov 08, 2017, 06:01 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 06, 2017 | Sale | $24.98 | 20,914 | 522,432 | 31,102 | Nov 08, 2017, 06:01 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 08, 2017 | Sale | $30.09 | 300,000 | 9,027,000 | 31,102 | Nov 08, 2017, 06:01 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 07, 2017 | Sale | $25.78 | 75,409 | 1,944,044 | 31,102 | Nov 08, 2017, 06:01 PM |
| ROBIN HOWARD W | President & CEO | Nov 01, 2017 | Option Exercise | $11.34 | 83,334 | 945,008 | 235,838 | Nov 03, 2017, 06:07 PM |
| ROBIN HOWARD W | President & CEO | Nov 01, 2017 | Sale | $23.57 | 83,334 | 1,964,182 | 152,504 | Nov 03, 2017, 06:07 PM |
| ROBIN HOWARD W | President & CEO | Oct 09, 2017 | Option Exercise | $11.34 | 83,333 | 944,996 | 235,837 | Oct 10, 2017, 06:08 PM |
| ROBIN HOWARD W | President & CEO | Oct 09, 2017 | Sale | $24.20 | 83,333 | 2,016,659 | 152,504 | Oct 10, 2017, 06:08 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Oct 05, 2017 | Option Exercise | $10.69 | 7,583 | 81,062 | 65,816 | Oct 10, 2017, 06:07 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Oct 05, 2017 | Sale | $25.00 | 7,583 | 189,575 | 58,233 | Oct 10, 2017, 06:07 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Oct 05, 2017 | Option Exercise | $9.53 | 43,677 | 416,242 | 74,779 | Oct 10, 2017, 06:06 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Oct 05, 2017 | Sale | $24.97 | 43,677 | 1,090,615 | 31,102 | Oct 10, 2017, 06:06 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Oct 02, 2017 | Option Exercise | $11.34 | 120,000 | 1,360,800 | 183,414 | Oct 03, 2017, 06:06 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Oct 02, 2017 | Sale | $24.45 | 120,000 | 2,934,000 | 63,414 | Oct 03, 2017, 06:06 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Oct 02, 2017 | Option Exercise | $11.04 | 56,704 | 626,012 | 98,279 | Oct 03, 2017, 06:02 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Sep 29, 2017 | Option Exercise | $11.04 | 43,296 | 477,988 | 84,871 | Oct 03, 2017, 06:02 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Oct 02, 2017 | Sale | $24.21 | 56,704 | 1,372,804 | 41,575 | Oct 03, 2017, 06:02 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Sep 29, 2017 | Sale | $24.04 | 43,296 | 1,040,836 | 41,575 | Oct 03, 2017, 06:02 PM |
| Lingnau Lutz | Director | Sep 22, 2017 | Sale | $21.97 | 5,000 | 109,850 | 27,450 | Sep 25, 2017, 06:04 PM |
| KUEBLER CHRISTOPHER A | Director | Sep 22, 2017 | Sale | $21.86 | 4,000 | 87,440 | 40,500 | Sep 25, 2017, 06:03 PM |
| CHESS ROBERT | Director | Sep 21, 2017 | Sale | $21.72 | 6,400 | 139,008 | 274,223 | Sep 25, 2017, 06:02 PM |
| ROBIN HOWARD W | President & CEO | Sep 06, 2017 | Option Exercise | $11.34 | 83,333 | 944,996 | 235,837 | Sep 08, 2017, 06:08 PM |
| ROBIN HOWARD W | President & CEO | Sep 06, 2017 | Sale | $21.54 | 83,333 | 1,794,993 | 152,504 | Sep 08, 2017, 06:08 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2017 | Sale | $19.32 | 2,648 | 51,159 | 50,838 | Aug 18, 2017, 07:05 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2017 | Option Exercise | $11.34 | 83,334 | 945,008 | 235,838 | Aug 18, 2017, 07:05 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2017 | Sale | $19.26 | 91,714 | 1,766,081 | 152,504 | Aug 18, 2017, 07:05 PM |
| Nicholson John | SVP & Chief Operating Officer | Aug 16, 2017 | Sale | $19.32 | 3,177 | 61,380 | 224,066 | Aug 18, 2017, 07:04 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 16, 2017 | Sale | $19.32 | 3,177 | 61,380 | 63,414 | Aug 18, 2017, 07:04 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Aug 16, 2017 | Sale | $19.32 | 2,956 | 57,110 | 58,233 | Aug 18, 2017, 07:03 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Aug 16, 2017 | Sale | $19.32 | 1,997 | 38,582 | 41,575 | Aug 18, 2017, 07:02 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Aug 16, 2017 | Sale | $19.32 | 1,701 | 32,863 | 31,102 | Aug 18, 2017, 07:01 PM |
| WHITFIELD ROY A | Director | Aug 10, 2017 | Buy | $17.95 | 35,000 | 628,250 | 133,000 | Aug 14, 2017, 09:07 AM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 18, 2017 | Option Exercise | $11.04 | 54,920 | 606,317 | 98,492 | Jul 20, 2017, 05:08 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 18, 2017 | Sale | $21.10 | 54,920 | 1,158,812 | 43,572 | Jul 20, 2017, 05:08 PM |
| Lingnau Lutz | Director | Jul 14, 2017 | Option Exercise | $14.26 | 30,000 | 427,800 | 53,450 | Jul 18, 2017, 08:02 PM |
| Lingnau Lutz | Director | Jul 14, 2017 | Sale | $20.76 | 30,000 | 622,800 | 23,450 | Jul 18, 2017, 08:02 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 11, 2017 | Option Exercise | $11.04 | 8,389 | 92,615 | 51,961 | Jul 13, 2017, 08:01 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 12, 2017 | Option Exercise | $11.04 | 36,691 | 405,069 | 80,263 | Jul 13, 2017, 08:01 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 11, 2017 | Sale | $21.04 | 8,389 | 176,505 | 43,572 | Jul 13, 2017, 08:01 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 12, 2017 | Sale | $21.09 | 36,691 | 773,813 | 43,572 | Jul 13, 2017, 08:01 PM |
| Krivulka Joseph J | Director | Jun 26, 2017 | Option Exercise | $8.37 | 15,000 | 125,550 | 73,000 | Jun 28, 2017, 06:05 PM |
| Nicholson John | SVP & Chief Operating Officer | Jun 07, 2017 | Option Exercise | $6.34 | 150,000 | 951,000 | 328,943 | Jun 09, 2017, 06:02 PM |
| Nicholson John | SVP & Chief Operating Officer | Jun 07, 2017 | Sale | $19.24 | 101,700 | 1,956,708 | 227,243 | Jun 09, 2017, 06:02 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 16, 2017 | Sale | $19.55 | 2,651 | 51,827 | 52,986 | May 18, 2017, 08:50 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2017 | Sale | $19.55 | 8,388 | 163,985 | 160,884 | May 18, 2017, 08:50 PM |
| Nicholson John | SVP & Chief Operating Officer | May 16, 2017 | Sale | $19.55 | 3,146 | 61,504 | 178,943 | May 18, 2017, 08:49 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 16, 2017 | Sale | $19.55 | 3,179 | 62,149 | 66,091 | May 18, 2017, 08:48 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | May 16, 2017 | Sale | $19.55 | 2,959 | 57,848 | 60,689 | May 18, 2017, 08:47 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | May 16, 2017 | Sale | $19.55 | 1,450 | 28,347 | 43,572 | May 18, 2017, 08:46 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | May 16, 2017 | Sale | $19.55 | 1,701 | 33,255 | 32,803 | May 18, 2017, 08:45 PM |
| CHESS ROBERT | Director | May 15, 2017 | Option Exercise | $8.37 | 5,000 | 41,850 | 276,623 | May 17, 2017, 06:02 PM |
| CHESS ROBERT | Director | May 15, 2017 | Sale | $19.79 | 5,000 | 98,950 | 271,623 | May 17, 2017, 06:02 PM |
| CHESS ROBERT | Director | Apr 17, 2017 | Option Exercise | $8.37 | 5,000 | 41,850 | 276,623 | Apr 19, 2017, 07:30 PM |
| CHESS ROBERT | Director | Apr 17, 2017 | Sale | $18.72 | 5,000 | 93,600 | 271,623 | Apr 19, 2017, 07:30 PM |
| Lingnau Lutz | Director | Apr 07, 2017 | Sale | $20.05 | 7,000 | 140,350 | 23,450 | Apr 11, 2017, 06:04 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 05, 2017 | Option Exercise | $9.53 | 100,000 | 953,000 | 134,504 | Apr 07, 2017, 06:07 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 05, 2017 | Sale | $21.70 | 100,000 | 2,170,000 | 34,504 | Apr 07, 2017, 06:07 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 05, 2017 | Option Exercise | $13.70 | 180,000 | 2,466,000 | 243,648 | Apr 07, 2017, 06:05 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 05, 2017 | Sale | $21.70 | 180,000 | 3,906,000 | 63,648 | Apr 07, 2017, 06:05 PM |
| KUEBLER CHRISTOPHER A | Director | Apr 05, 2017 | Option Exercise | $8.37 | 15,000 | 125,550 | 50,500 | Apr 07, 2017, 06:01 PM |
| KUEBLER CHRISTOPHER A | Director | Apr 05, 2017 | Sale | $21.88 | 15,000 | 328,200 | 35,500 | Apr 07, 2017, 06:01 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Mar 20, 2017 | Option Exercise | $9.96 | 112,500 | 1,120,875 | 168,137 | Mar 22, 2017, 06:04 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Mar 20, 2017 | Sale | $19.69 | 112,500 | 2,215,125 | 55,637 | Mar 22, 2017, 06:04 PM |
| WHITFIELD ROY A | Director | Mar 15, 2017 | Option Exercise | $8.37 | 14,000 | 117,180 | 98,000 | Mar 17, 2017, 06:02 PM |
| CHESS ROBERT | Director | Mar 14, 2017 | Option Exercise | $8.37 | 5,000 | 41,850 | 276,623 | Mar 16, 2017, 06:02 PM |
| CHESS ROBERT | Director | Mar 14, 2017 | Sale | $15.41 | 5,000 | 77,050 | 271,623 | Mar 16, 2017, 06:02 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Mar 03, 2017 | Option Exercise | $8.57 | 32,494 | 278,512 | 94,270 | Mar 03, 2017, 07:04 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Mar 02, 2017 | Option Exercise | $6.34 | 167,506 | 1,061,988 | 236,776 | Mar 03, 2017, 07:04 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Mar 03, 2017 | Sale | $15.21 | 32,494 | 494,234 | 69,270 | Mar 03, 2017, 07:04 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Mar 02, 2017 | Sale | $15.15 | 167,506 | 2,537,716 | 69,270 | Mar 03, 2017, 07:04 PM |
| Lingnau Lutz | Director | Feb 21, 2017 | Option Exercise | $5.14 | 30,000 | 154,200 | 60,450 | Feb 23, 2017, 06:32 PM |
| Lingnau Lutz | Director | Feb 21, 2017 | Sale | $13.08 | 30,000 | 392,400 | 30,450 | Feb 23, 2017, 06:32 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 16, 2017 | Sale | $13.14 | 1,965 | 25,820 | 55,637 | Feb 17, 2017, 08:06 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2017 | Sale | $13.14 | 8,636 | 113,477 | 169,272 | Feb 17, 2017, 08:06 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 16, 2017 | Sale | $13.14 | 3,237 | 42,534 | 182,089 | Feb 17, 2017, 08:05 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Feb 16, 2017 | Sale | $13.14 | 2,359 | 30,997 | 69,270 | Feb 17, 2017, 08:04 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Feb 16, 2017 | Sale | $13.14 | 2,195 | 28,842 | 63,648 | Feb 17, 2017, 08:04 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Feb 16, 2017 | Sale | $13.14 | 1,457 | 19,145 | 45,022 | Feb 17, 2017, 08:03 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Feb 16, 2017 | Sale | $13.14 | 1,261 | 16,570 | 34,504 | Feb 17, 2017, 08:02 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 10, 2017 | Option Exercise | $4.65 | 45,000 | 209,250 | 185,326 | Feb 10, 2017, 08:11 PM |
| ROBIN HOWARD W | President & CEO | Feb 08, 2017 | Option Exercise | $4.65 | 87,500 | 406,875 | 265,408 | Feb 10, 2017, 08:10 PM |
| ROBIN HOWARD W | President & CEO | Feb 08, 2017 | Sale | $13.04 | 87,500 | 1,141,000 | 177,908 | Feb 10, 2017, 08:10 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 03, 2017 | Option Exercise | $4.65 | 8,505 | 39,548 | 148,831 | Feb 06, 2017, 05:20 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 02, 2017 | Option Exercise | $4.65 | 66,495 | 309,202 | 206,821 | Feb 06, 2017, 05:20 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 02, 2017 | Sale | $12.38 | 66,495 | 823,208 | 140,326 | Feb 06, 2017, 05:20 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 03, 2017 | Sale | $12.48 | 8,505 | 106,142 | 140,326 | Feb 06, 2017, 05:20 PM |
| ROBIN HOWARD W | President & CEO | Jan 17, 2017 | Option Exercise | $4.65 | 87,500 | 406,875 | 265,408 | Jan 19, 2017, 08:01 PM |
| ROBIN HOWARD W | President & CEO | Jan 17, 2017 | Sale | $12.35 | 87,500 | 1,080,625 | 177,908 | Jan 19, 2017, 08:01 PM |
| ROBIN HOWARD W | President & CEO | Dec 07, 2016 | Option Exercise | $4.65 | 87,500 | 406,875 | 210,408 | Dec 09, 2016, 06:03 PM |
| ROBIN HOWARD W | President & CEO | Dec 07, 2016 | Sale | $12.24 | 87,500 | 1,071,000 | 122,908 | Dec 09, 2016, 06:03 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 16, 2016 | Sale | $13.96 | 1,986 | 27,725 | 42,102 | Nov 18, 2016, 06:12 PM |
| ROBIN HOWARD W | President & CEO | Nov 17, 2016 | Option Exercise | $4.65 | 87,500 | 406,875 | 210,408 | Nov 18, 2016, 06:12 PM |
| ROBIN HOWARD W | President & CEO | Nov 17, 2016 | Sale | $13.87 | 87,500 | 1,213,625 | 122,908 | Nov 18, 2016, 06:12 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2016 | Sale | $13.96 | 5,958 | 83,174 | 122,908 | Nov 18, 2016, 06:12 PM |
| Nicholson John | SVP & Chief Operating Officer | Nov 16, 2016 | Sale | $13.96 | 1,654 | 23,090 | 120,326 | Nov 18, 2016, 06:11 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Nov 16, 2016 | Sale | $13.96 | 1,654 | 23,090 | 51,129 | Nov 18, 2016, 06:10 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 16, 2016 | Sale | $13.96 | 1,654 | 23,090 | 50,343 | Nov 18, 2016, 06:09 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Nov 16, 2016 | Sale | $13.96 | 848 | 11,838 | 26,479 | Nov 18, 2016, 06:08 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 16, 2016 | Sale | $13.96 | 670 | 9,353 | 18,265 | Nov 18, 2016, 06:07 PM |
| GREER R SCOTT | Director | Oct 24, 2016 | Buy | $13.50 | 15,000 | 202,500 | 121,333 | Oct 25, 2016, 05:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 04, 2016 | Option Exercise | $4.65 | 87,500 | 406,875 | 216,366 | Oct 06, 2016, 05:07 PM |
| ROBIN HOWARD W | President & CEO | Oct 04, 2016 | Sale | $17.06 | 87,500 | 1,492,750 | 128,866 | Oct 06, 2016, 05:07 PM |
| WHITFIELD ROY A | Director | Sep 23, 2016 | Option Exercise | $5.21 | 46,000 | 239,820 | 84,000 | Sep 27, 2016, 05:09 PM |
| Lingnau Lutz | Director | Sep 15, 2016 | Sale | $19.06 | 9,000 | 171,540 | 7,450 | Sep 19, 2016, 05:16 PM |
| KUEBLER CHRISTOPHER A | Director | Sep 16, 2016 | Sale | $19.13 | 7,500 | 143,475 | 27,500 | Sep 19, 2016, 05:15 PM |
| CHESS ROBERT | Director | Sep 15, 2016 | Sale | $19.21 | 12,000 | 230,520 | 248,623 | Sep 19, 2016, 05:13 PM |
| ROBIN HOWARD W | President & CEO | Sep 01, 2016 | Option Exercise | $4.65 | 87,500 | 406,875 | 216,366 | Sep 02, 2016, 08:03 PM |
| ROBIN HOWARD W | President & CEO | Sep 01, 2016 | Sale | $17.83 | 87,500 | 1,560,125 | 128,886 | Sep 02, 2016, 08:03 PM |
| Nicholson John | SVP & Chief Operating Officer | Aug 16, 2016 | Sale | $17.56 | 3,317 | 58,247 | 121,980 | Aug 17, 2016, 05:45 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2016 | Sale | $17.56 | 3,971 | 69,731 | 44,088 | Aug 17, 2016, 05:42 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2016 | Sale | $17.56 | 11,817 | 207,507 | 128,866 | Aug 17, 2016, 05:41 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 16, 2016 | Sale | $17.56 | 3,305 | 58,036 | 52,783 | Aug 17, 2016, 05:39 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Aug 16, 2016 | Sale | $17.56 | 3,305 | 58,036 | 51,997 | Aug 17, 2016, 05:38 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Aug 16, 2016 | Sale | $17.56 | 1,685 | 29,589 | 27,327 | Aug 17, 2016, 05:38 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Aug 16, 2016 | Sale | $17.56 | 1,336 | 23,460 | 18,935 | Aug 17, 2016, 05:37 PM |
| CHESS ROBERT | Director | Aug 01, 2016 | Option Exercise | $5.15 | 5,000 | 25,750 | 265,623 | Aug 03, 2016, 07:01 PM |
| CHESS ROBERT | Director | Aug 01, 2016 | Sale | $17.26 | 5,000 | 86,300 | 260,623 | Aug 03, 2016, 07:01 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jul 11, 2016 | Option Exercise | $4.65 | 100,000 | 465,000 | 106,809 | Jul 13, 2016, 05:08 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jul 11, 2016 | Sale | $15.09 | 100,000 | 1,509,000 | 6,809 | Jul 13, 2016, 05:08 PM |
| CHESS ROBERT | Director | Jul 01, 2016 | Option Exercise | $5.15 | 5,000 | 25,750 | 265,623 | Jul 05, 2016, 05:21 PM |
| CHESS ROBERT | Director | Jul 01, 2016 | Sale | $14.10 | 5,000 | 70,500 | 260,623 | Jul 05, 2016, 05:21 PM |
| CHESS ROBERT | Director | Jun 01, 2016 | Option Exercise | $5.15 | 5,000 | 25,750 | 265,623 | Jun 03, 2016, 05:05 PM |
| CHESS ROBERT | Director | Jun 01, 2016 | Sale | $15.50 | 5,000 | 77,500 | 260,623 | Jun 03, 2016, 05:05 PM |
| Nicholson John | SVP & Chief Financial Officer | May 16, 2016 | Option Exercise | $0.00 | 2,167 | 0 | 78,486 | May 18, 2016, 05:23 PM |
| Nicholson John | SVP & Chief Financial Officer | May 17, 2016 | Sale | $13.58 | 856 | 11,624 | 77,630 | May 18, 2016, 05:23 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2016 | Option Exercise | $0.00 | 5,625 | 1 | 19,103 | May 18, 2016, 05:23 PM |
| ROBIN HOWARD W | President & CEO | May 17, 2016 | Sale | $13.58 | 2,170 | 29,469 | 16,933 | May 18, 2016, 05:23 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | May 16, 2016 | Option Exercise | $0.00 | 875 | 0 | 1,360 | May 18, 2016, 05:15 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | May 17, 2016 | Sale | $13.58 | 339 | 4,604 | 1,021 | May 18, 2016, 05:15 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | May 16, 2016 | Option Exercise | $0.00 | 1,250 | 0 | 1,944 | May 18, 2016, 05:14 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | May 17, 2016 | Sale | $13.58 | 432 | 5,867 | 1,512 | May 18, 2016, 05:14 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | May 16, 2016 | Option Exercise | $0.00 | 2,167 | 0 | 7,970 | May 18, 2016, 05:13 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | May 17, 2016 | Sale | $13.58 | 835 | 11,339 | 7,135 | May 18, 2016, 05:13 PM |
| Labrucherie Gil M | SVP & General Counsel | May 16, 2016 | Option Exercise | $0.00 | 2,167 | 0 | 8,757 | May 18, 2016, 05:12 PM |
| Labrucherie Gil M | SVP & General Counsel | May 17, 2016 | Sale | $13.58 | 836 | 11,353 | 7,921 | May 18, 2016, 05:12 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 16, 2016 | Option Exercise | $0.00 | 1,875 | 0 | 7,033 | May 18, 2016, 05:08 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 17, 2016 | Sale | $13.58 | 724 | 9,832 | 6,309 | May 18, 2016, 05:08 PM |
| Lingnau Lutz | Director | Apr 25, 2016 | Option Exercise | $8.37 | 15,000 | 125,550 | 31,450 | Apr 27, 2016, 05:08 PM |
| Lingnau Lutz | Director | Apr 25, 2016 | Sale | $16.27 | 15,000 | 244,050 | 16,450 | Apr 27, 2016, 05:08 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Mar 09, 2016 | Option Exercise | $6.65 | 15,000 | 99,750 | 20,158 | Mar 11, 2016, 05:06 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Mar 09, 2016 | Sale | $11.79 | 15,000 | 176,850 | 5,158 | Mar 11, 2016, 05:06 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Feb 16, 2016 | Option Exercise | $0.00 | 1,250 | 0 | 1,250 | Feb 18, 2016, 07:49 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Feb 17, 2016 | Sale | $11.92 | 556 | 6,628 | 694 | Feb 18, 2016, 07:49 PM |
| Nicholson John | SVP & Chief Financial Officer | Feb 16, 2016 | Option Exercise | $0.00 | 2,166 | 0 | 77,282 | Feb 18, 2016, 07:48 PM |
| Nicholson John | SVP & Chief Financial Officer | Feb 17, 2016 | Sale | $11.92 | 963 | 11,479 | 76,319 | Feb 18, 2016, 07:48 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2016 | Option Exercise | $0.00 | 5,625 | 1 | 15,625 | Feb 18, 2016, 07:48 PM |
| ROBIN HOWARD W | President & CEO | Feb 17, 2016 | Sale | $11.92 | 2,147 | 25,592 | 13,478 | Feb 18, 2016, 07:48 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Feb 16, 2016 | Option Exercise | $0.00 | 875 | 0 | 875 | Feb 18, 2016, 07:47 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Feb 17, 2016 | Sale | $11.92 | 390 | 4,649 | 485 | Feb 18, 2016, 07:47 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 16, 2016 | Option Exercise | $0.00 | 1,875 | 0 | 5,874 | Feb 18, 2016, 07:46 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 17, 2016 | Sale | $11.92 | 716 | 8,535 | 5,158 | Feb 18, 2016, 07:46 PM |
| Labrucherie Gil M | SVP & General Counsel | Feb 16, 2016 | Option Exercise | $0.00 | 2,166 | 0 | 7,417 | Feb 18, 2016, 07:45 PM |
| Labrucherie Gil M | SVP & General Counsel | Feb 17, 2016 | Sale | $11.92 | 827 | 9,858 | 6,590 | Feb 18, 2016, 07:45 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Feb 16, 2016 | Option Exercise | $0.00 | 2,166 | 0 | 6,766 | Feb 18, 2016, 07:45 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Feb 17, 2016 | Sale | $11.92 | 963 | 11,479 | 5,803 | Feb 18, 2016, 07:45 PM |
| Labrucherie Gil M | SVP & General Counsel | Feb 10, 2016 | Option Exercise | $6.46 | 11,666 | 75,362 | 16,917 | Feb 12, 2016, 05:20 PM |
| Labrucherie Gil M | SVP & General Counsel | Feb 10, 2016 | Sale | $11.49 | 11,666 | 134,042 | 5,251 | Feb 12, 2016, 05:20 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 10, 2016 | Option Exercise | $6.65 | 15,000 | 99,750 | 18,999 | Feb 12, 2016, 05:19 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 10, 2016 | Sale | $11.49 | 15,000 | 172,350 | 3,999 | Feb 12, 2016, 05:19 PM |
| ROBIN HOWARD W | President & CEO | Feb 10, 2016 | Option Exercise | $6.46 | 66,666 | 430,662 | 76,666 | Feb 12, 2016, 05:18 PM |
| ROBIN HOWARD W | President & CEO | Feb 10, 2016 | Sale | $11.49 | 66,666 | 765,992 | 10,000 | Feb 12, 2016, 05:18 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jan 19, 2016 | Option Exercise | $6.65 | 15,000 | 99,750 | 18,999 | Jan 21, 2016, 06:06 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jan 19, 2016 | Sale | $14.12 | 15,000 | 211,800 | 3,999 | Jan 21, 2016, 06:06 PM |
| ROBIN HOWARD W | President & CEO | Jan 19, 2016 | Option Exercise | $6.46 | 66,667 | 430,669 | 76,667 | Jan 21, 2016, 06:05 PM |
| ROBIN HOWARD W | President & CEO | Jan 19, 2016 | Sale | $14.12 | 66,667 | 941,338 | 10,000 | Jan 21, 2016, 06:05 PM |
| Lingnau Lutz | Director | Jan 20, 2016 | Option Exercise | $5.15 | 15,000 | 77,250 | 31,450 | Jan 21, 2016, 06:04 PM |
| Lingnau Lutz | Director | Jan 20, 2016 | Sale | $14.51 | 15,000 | 217,650 | 16,450 | Jan 21, 2016, 06:04 PM |
| Labrucherie Gil M | SVP & General Counsel | Jan 19, 2016 | Option Exercise | $6.46 | 11,667 | 75,369 | 16,918 | Jan 21, 2016, 06:02 PM |
| Labrucherie Gil M | SVP & General Counsel | Jan 19, 2016 | Sale | $14.12 | 11,667 | 164,738 | 5,251 | Jan 21, 2016, 06:02 PM |
| Labrucherie Gil M | SVP & General Counsel | Dec 03, 2015 | Option Exercise | $6.85 | 45,001 | 308,040 | 50,252 | Dec 07, 2015, 05:36 PM |
| Labrucherie Gil M | SVP & General Counsel | Dec 03, 2015 | Sale | $15.87 | 45,001 | 714,166 | 5,251 | Dec 07, 2015, 05:36 PM |
| ROBIN HOWARD W | President & CEO | Dec 03, 2015 | Option Exercise | $6.70 | 125,001 | 837,840 | 135,001 | Dec 07, 2015, 05:33 PM |
| ROBIN HOWARD W | President & CEO | Dec 03, 2015 | Sale | $15.87 | 125,001 | 1,983,766 | 10,000 | Dec 07, 2015, 05:33 PM |
| KUEBLER CHRISTOPHER A | Director | Dec 04, 2015 | Option Exercise | $5.15 | 15,000 | 77,250 | 35,000 | Dec 07, 2015, 05:31 PM |
| KUEBLER CHRISTOPHER A | Director | Dec 04, 2015 | Sale | $15.82 | 15,000 | 237,300 | 20,000 | Dec 07, 2015, 05:31 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Dec 03, 2015 | Option Exercise | $6.65 | 15,000 | 99,750 | 18,999 | Dec 07, 2015, 05:29 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Dec 03, 2015 | Sale | $15.87 | 15,000 | 238,050 | 3,999 | Dec 07, 2015, 05:29 PM |
| WANG SUSAN | Director | Nov 19, 2015 | Option Exercise | $5.14 | 15,128 | 77,758 | 35,128 | Nov 20, 2015, 05:27 PM |
| WANG SUSAN | Director | Nov 18, 2015 | Option Exercise | $7.52 | 20,372 | 153,162 | 35,000 | Nov 20, 2015, 05:27 PM |
| WANG SUSAN | Director | Nov 20, 2015 | Option Exercise | $8.45 | 49,500 | 418,430 | 60,000 | Nov 20, 2015, 05:27 PM |
| WANG SUSAN | Director | Nov 18, 2015 | Sale | $15.00 | 20,372 | 305,580 | 20,000 | Nov 20, 2015, 05:27 PM |
| WANG SUSAN | Director | Nov 20, 2015 | Sale | $15.02 | 49,500 | 743,490 | 20,000 | Nov 20, 2015, 05:27 PM |
| WANG SUSAN | Director | Nov 19, 2015 | Sale | $15.02 | 15,128 | 227,223 | 20,000 | Nov 20, 2015, 05:27 PM |
| ROBIN HOWARD W | President & CEO | Nov 11, 2015 | Option Exercise | $6.70 | 125,000 | 837,833 | 135,000 | Nov 13, 2015, 05:41 PM |
| ROBIN HOWARD W | President & CEO | Nov 11, 2015 | Sale | $13.52 | 125,000 | 1,690,000 | 10,000 | Nov 13, 2015, 05:41 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 11, 2015 | Option Exercise | $6.85 | 45,000 | 308,033 | 49,751 | Nov 13, 2015, 05:35 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 11, 2015 | Sale | $13.52 | 45,000 | 608,400 | 4,751 | Nov 13, 2015, 05:35 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 11, 2015 | Option Exercise | $6.65 | 15,000 | 99,750 | 18,499 | Nov 13, 2015, 04:12 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 11, 2015 | Sale | $13.52 | 15,000 | 202,800 | 3,499 | Nov 13, 2015, 04:12 PM |
| Lingnau Lutz | Director | Oct 28, 2015 | Option Exercise | $6.65 | 12,500 | 83,125 | 28,950 | Oct 30, 2015, 04:17 PM |
| Lingnau Lutz | Director | Oct 28, 2015 | Sale | $12.00 | 12,500 | 150,000 | 16,450 | Oct 30, 2015, 04:17 PM |
| GREER R SCOTT | Director | Oct 15, 2015 | Option Exercise | $11.34 | 32,500 | 368,550 | 83,333 | Oct 19, 2015, 05:01 PM |
| ROBIN HOWARD W | President & CEO | Oct 06, 2015 | Option Exercise | $6.70 | 125,000 | 837,833 | 135,000 | Oct 08, 2015, 07:12 PM |
| ROBIN HOWARD W | President & CEO | Oct 06, 2015 | Sale | $10.99 | 125,000 | 1,373,750 | 10,000 | Oct 08, 2015, 07:12 PM |
| Labrucherie Gil M | SVP & General Counsel | Oct 06, 2015 | Option Exercise | $6.85 | 45,000 | 308,033 | 49,751 | Oct 08, 2015, 07:11 PM |
| Labrucherie Gil M | SVP & General Counsel | Oct 06, 2015 | Sale | $10.99 | 45,000 | 494,550 | 4,751 | Oct 08, 2015, 07:11 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Oct 06, 2015 | Option Exercise | $6.65 | 15,000 | 99,750 | 18,499 | Oct 08, 2015, 07:09 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Oct 06, 2015 | Sale | $10.99 | 15,000 | 164,850 | 3,499 | Oct 08, 2015, 07:09 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Sep 23, 2015 | Option Exercise | $6.65 | 10,000 | 66,500 | 13,499 | Sep 25, 2015, 05:25 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Sep 23, 2015 | Sale | $13.04 | 10,000 | 130,400 | 3,499 | Sep 25, 2015, 05:25 PM |
| ROBIN HOWARD W | President & CEO | Sep 23, 2015 | Option Exercise | $6.70 | 124,999 | 837,827 | 134,999 | Sep 25, 2015, 05:24 PM |
| ROBIN HOWARD W | President & CEO | Sep 23, 2015 | Sale | $13.04 | 124,999 | 1,629,987 | 10,000 | Sep 25, 2015, 05:24 PM |
| Labrucherie Gil M | SVP & General Counsel | Sep 23, 2015 | Option Exercise | $6.85 | 44,999 | 308,027 | 49,750 | Sep 25, 2015, 05:22 PM |
| Labrucherie Gil M | SVP & General Counsel | Sep 23, 2015 | Sale | $13.04 | 44,999 | 586,787 | 4,751 | Sep 25, 2015, 05:22 PM |
| WHITFIELD ROY A | Director | Sep 11, 2015 | Option Exercise | $8.81 | 15,000 | 132,150 | 15,000 | Sep 15, 2015, 04:12 PM |
| Labrucherie Gil M | SVP & General Counsel | Aug 13, 2015 | Option Exercise | $6.98 | 33,333 | 232,664 | 38,084 | Aug 17, 2015, 04:04 PM |
| Labrucherie Gil M | SVP & General Counsel | Aug 13, 2015 | Sale | $10.89 | 33,333 | 362,996 | 4,751 | Aug 17, 2015, 04:04 PM |
| ROBIN HOWARD W | President & CEO | Aug 13, 2015 | Option Exercise | $6.98 | 58,333 | 407,164 | 68,333 | Aug 17, 2015, 04:03 PM |
| ROBIN HOWARD W | President & CEO | Aug 13, 2015 | Sale | $10.89 | 58,333 | 635,246 | 10,000 | Aug 17, 2015, 04:03 PM |
| Nicholson John | SVP & Chief Financial Officer | Aug 11, 2015 | Option Exercise | $8.26 | 295,000 | 2,437,100 | 164,908 | Aug 13, 2015, 05:10 PM |
| Nicholson John | SVP & Chief Financial Officer | Aug 12, 2015 | Option Exercise | $6.49 | 90,000 | 584,000 | 141,116 | Aug 13, 2015, 05:10 PM |
| Nicholson John | SVP & Chief Financial Officer | Aug 12, 2015 | Sale | $10.48 | 69,976 | 733,325 | 75,116 | Aug 13, 2015, 05:10 PM |
| Nicholson John | SVP & Chief Financial Officer | Aug 11, 2015 | Sale | $10.87 | 249,908 | 2,716,089 | 10,000 | Aug 13, 2015, 05:10 PM |
| Krivulka Joseph J | Director | Jul 24, 2015 | Option Exercise | $8.81 | 15,000 | 132,150 | 35,000 | Jul 28, 2015, 04:06 PM |
| ROBIN HOWARD W | President & CEO | Jul 14, 2015 | Option Exercise | $6.98 | 58,334 | 407,171 | 68,334 | Jul 16, 2015, 04:16 PM |
| ROBIN HOWARD W | President & CEO | Jul 14, 2015 | Sale | $11.78 | 58,334 | 687,175 | 10,000 | Jul 16, 2015, 04:16 PM |
| Labrucherie Gil M | SVP & General Counsel | Jul 14, 2015 | Option Exercise | $6.98 | 33,334 | 232,671 | 37,585 | Jul 16, 2015, 04:14 PM |
| Labrucherie Gil M | SVP & General Counsel | Jul 14, 2015 | Sale | $11.78 | 33,334 | 392,675 | 4,251 | Jul 16, 2015, 04:14 PM |
| WANG SUSAN | Director | Jun 29, 2015 | Option Exercise | $6.98 | 30,000 | 209,400 | 35,000 | Jul 01, 2015, 04:09 PM |
| WANG SUSAN | Director | Jun 29, 2015 | Sale | $12.70 | 30,000 | 381,000 | 20,000 | Jul 01, 2015, 04:09 PM |
| CHESS ROBERT | Director | Jun 19, 2015 | Option Exercise | $8.81 | 15,000 | 132,150 | 275,623 | Jun 23, 2015, 04:05 PM |
| CHESS ROBERT | Director | Jun 19, 2015 | Sale | $11.81 | 15,000 | 177,150 | 260,623 | Jun 23, 2015, 04:05 PM |
| Lingnau Lutz | Director | Jun 15, 2015 | Option Exercise | $6.65 | 25,000 | 166,250 | 41,450 | Jun 17, 2015, 04:07 PM |
| Lingnau Lutz | Director | Jun 15, 2015 | Sale | $11.15 | 25,000 | 278,750 | 16,450 | Jun 17, 2015, 04:07 PM |
| KUEBLER CHRISTOPHER A | Director | Jan 13, 2015 | Option Exercise | $8.81 | 15,000 | 132,150 | 35,000 | Jan 15, 2015, 05:54 PM |
| KUEBLER CHRISTOPHER A | Director | Jan 13, 2015 | Sale | $16.00 | 15,000 | 240,000 | 20,000 | Jan 15, 2015, 05:54 PM |
| CHESS ROBERT | Director | Dec 29, 2014 | Option Exercise | $15.24 | 29,500 | 449,580 | 290,123 | Dec 31, 2014, 05:37 PM |
| CHESS ROBERT | Director | Dec 29, 2014 | Sale | $15.34 | 29,500 | 452,530 | 260,623 | Dec 31, 2014, 05:37 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Dec 22, 2014 | Option Exercise | $11.38 | 5,000 | 56,900 | 7,999 | Dec 24, 2014, 04:09 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Dec 22, 2014 | Sale | $15.56 | 5,000 | 77,800 | 2,999 | Dec 24, 2014, 04:09 PM |
| Labrucherie Gil M | SVP & General Counsel | Dec 01, 2014 | Option Exercise | $4.65 | 30,000 | 139,500 | 34,251 | Dec 02, 2014, 07:23 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 28, 2014 | Option Exercise | $4.65 | 90,000 | 418,500 | 94,251 | Dec 02, 2014, 07:23 PM |
| Labrucherie Gil M | SVP & General Counsel | Dec 01, 2014 | Sale | $17.00 | 30,000 | 510,000 | 4,251 | Dec 02, 2014, 07:23 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 28, 2014 | Sale | $17.02 | 90,000 | 1,531,800 | 4,251 | Dec 02, 2014, 07:23 PM |
| ROBIN HOWARD W | President & CEO | Nov 28, 2014 | Option Exercise | $6.98 | 140,944 | 983,789 | 150,944 | Dec 02, 2014, 07:22 PM |
| ROBIN HOWARD W | President & CEO | Dec 01, 2014 | Option Exercise | $6.98 | 209,056 | 1,459,211 | 219,056 | Dec 02, 2014, 07:22 PM |
| ROBIN HOWARD W | President & CEO | Dec 01, 2014 | Sale | $17.00 | 209,056 | 3,553,952 | 10,000 | Dec 02, 2014, 07:22 PM |
| ROBIN HOWARD W | President & CEO | Nov 28, 2014 | Sale | $17.02 | 140,944 | 2,398,867 | 10,000 | Dec 02, 2014, 07:22 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 24, 2014 | Option Exercise | $13.02 | 10,500 | 136,710 | 14,251 | Nov 26, 2014, 05:47 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 24, 2014 | Sale | $15.04 | 10,500 | 157,920 | 3,751 | Nov 26, 2014, 05:47 PM |
| ROBIN HOWARD W | President & CEO | Nov 24, 2014 | Option Exercise | $14.52 | 132,800 | 1,928,256 | 142,800 | Nov 26, 2014, 05:41 PM |
| ROBIN HOWARD W | President & CEO | Nov 25, 2014 | Option Exercise | $14.52 | 467,200 | 6,783,744 | 477,200 | Nov 26, 2014, 05:41 PM |
| ROBIN HOWARD W | President & CEO | Nov 25, 2014 | Sale | $15.31 | 467,200 | 7,152,832 | 10,000 | Nov 26, 2014, 05:41 PM |
| ROBIN HOWARD W | President & CEO | Nov 24, 2014 | Sale | $15.02 | 132,800 | 1,994,656 | 10,000 | Nov 26, 2014, 05:41 PM |
| Lingnau Lutz | Director | Nov 24, 2014 | Option Exercise | $8.81 | 15,000 | 132,150 | 31,450 | Nov 26, 2014, 05:39 PM |
| Lingnau Lutz | Director | Nov 24, 2014 | Sale | $15.02 | 15,000 | 225,300 | 16,450 | Nov 26, 2014, 05:39 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 03, 2014 | Option Exercise | $11.38 | 9,900 | 112,662 | 13,651 | Nov 04, 2014, 01:41 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 03, 2014 | Sale | $13.78 | 9,900 | 136,422 | 3,751 | Nov 04, 2014, 01:41 PM |
| KUEBLER CHRISTOPHER A | Director | Aug 05, 2013 | Option Exercise | $11.41 | 12,500 | 142,625 | 32,500 | Aug 08, 2013, 05:14 PM |
| KUEBLER CHRISTOPHER A | Director | Aug 05, 2013 | Sale | $12.41 | 12,500 | 155,125 | 20,000 | Aug 08, 2013, 05:14 PM |
| WHITFIELD ROY A | Director | Aug 05, 2013 | Option Exercise | $11.41 | 12,500 | 142,625 | 32,500 | Aug 07, 2013, 04:30 PM |
| WHITFIELD ROY A | Director | Aug 05, 2013 | Sale | $12.41 | 12,500 | 155,125 | 20,000 | Aug 07, 2013, 04:30 PM |
| KUEBLER CHRISTOPHER A | Director | Sep 27, 2012 | Option Exercise | $8.66 | 12,500 | 108,250 | 32,500 | Oct 01, 2012, 04:02 PM |
| KUEBLER CHRISTOPHER A | Director | Sep 27, 2012 | Sale | $10.66 | 12,500 | 133,250 | 20,000 | Oct 01, 2012, 04:02 PM |
| WINGER DENNIS L | Director | Sep 14, 2012 | Buy | $9.18 | 5,000 | 45,908 | 5,000 | Sep 18, 2012, 02:34 PM |
| CHESS ROBERT | Director | Jul 13, 2012 | Option Exercise | $6.12 | 24,001 | 146,886 | 284,624 | Jul 17, 2012, 04:10 PM |
| CHESS ROBERT | Director | Jul 13, 2012 | Sale | $8.50 | 24,001 | 204,009 | 260,623 | Jul 17, 2012, 04:10 PM |
| CHESS ROBERT | Director | Mar 08, 2011 | Sale | $9.00 | 4,500 | 40,500 | 255,709 | Mar 09, 2011, 12:14 PM |
Load More Insider Transactions
Buy
Sale
Option Exercise
| Owner | Relationship | Date | Value($) |
| Zalevsky Jonathan | Chief R&D Officer | 11/17/2023 | 4,727 |
| Wilson Mark Andrew | Chief Legal Officer | 11/17/2023 | 3,518 |
| ROBIN HOWARD W | President & CEO | 11/17/2023 | 9,740 |
| Curet Myriam | Director | 09/18/2023 | 3,008 |
| CHESS ROBERT | Director | 09/22/2022 | 6,834 |
| Ajer Jeffrey Robert | Director | 09/18/2023 | 3,008 |
| Zalevsky Jonathan | Chief R&D Officer | 08/16/2023 | 7,568 |
| Wilson Mark Andrew | Chief Legal Officer | 08/16/2023 | 5,632 |
| ROBIN HOWARD W | President & CEO | 08/16/2023 | 15,598 |
| WHITFIELD ROY A | Director | 06/14/2023 | 17,100 |
| Zalevsky Jonathan | Chief R&D Officer | 05/16/2023 | 7,050 |
| Wilson Mark Andrew | Chief Legal Officer | 05/16/2023 | 5,431 |
| ROBIN HOWARD W | President & CEO | 05/16/2023 | 14,660 |
| Zalevsky Jonathan | Chief R&D Officer | 02/16/2023 | 31,452 |
| Wilson Mark Andrew | Chief Legal Officer | 02/16/2023 | 24,825 |
| Thomsen Jillian B. | Chief Financial Officer | 02/16/2023 | 30,801 |
| ROBIN HOWARD W | President & CEO | 02/16/2023 | 58,905 |
| Zalevsky Jonathan | Chief R&D Officer | 11/16/2022 | 48,052 |
| Wilson Mark Andrew | Chief Legal Officer | 11/16/2022 | 31,023 |
| Thomsen Jillian B. | Chief Financial Officer | 11/16/2022 | 39,609 |
| ROBIN HOWARD W | President & CEO | 11/16/2022 | 135,710 |
| Curet Myriam | Director | 09/23/2022 | 13,266 |
| Ajer Jeffrey Robert | Director | 09/23/2022 | 13,266 |
| CHESS ROBERT | Director | 09/22/2022 | 16,269 |
| EASTHAM KARIN | Director | 09/13/2022 | 76,774 |
| Zalevsky Jonathan | Chief R&D Officer | 08/18/2022 | 342,779 |
| Zalevsky Jonathan | Chief R&D Officer | 08/16/2022 | 50,266 |
| Wilson Mark Andrew | SVP & General Counsel | 08/16/2022 | 15,180 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2022 | 9,549 |
| ROBIN HOWARD W | President & CEO | 08/16/2022 | 65,493 |
| Zalevsky Jonathan | Chief R&D Officer | 05/16/2022 | 85,608 |
| Wilson Mark Andrew | SVP & General Counsel | 05/16/2022 | 12,387 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/16/2022 | 23,072 |
| ROBIN HOWARD W | President & CEO | 05/16/2022 | 144,290 |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | 05/16/2022 | 18,138 |
| Labrucherie Gil M | SVP, COO & CFO | 05/16/2022 | 68,920 |
| Zalevsky Jonathan | Chief R&D Officer | 02/16/2022 | 119,486 |
| Wilson Mark Andrew | SVP & General Counsel | 02/16/2022 | 40,088 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/16/2022 | 25,875 |
| ROBIN HOWARD W | President & CEO | 02/16/2022 | 136,656 |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | 02/16/2022 | 53,129 |
| Labrucherie Gil M | SVP, COO & CFO | 02/16/2022 | 82,990 |
| Labrucherie Gil M | SVP, COO & CFO | 11/18/2021 | 38,070 |
| Labrucherie Gil M | SVP, COO & CFO | 11/16/2021 | 278,321 |
| Zalevsky Jonathan | Chief R&D Officer | 11/16/2021 | 274,636 |
| Wilson Mark Andrew | SVP & General Counsel | 11/16/2021 | 86,382 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/16/2021 | 88,712 |
| ROBIN HOWARD W | President & CEO | 11/16/2021 | 562,893 |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | 11/16/2021 | 79,763 |
| GREER R SCOTT | Director | 11/09/2021 | 160,000 |
| Curet Myriam | Director | 09/22/2021 | 65,164 |
| CHESS ROBERT | Director | 09/22/2021 | 82,524 |
| Ajer Jeffrey Robert | Director | 09/22/2021 | 65,164 |
| WHITFIELD ROY A | Director | 09/16/2021 | 552,000 |
| CHESS ROBERT | Director | 09/09/2021 | 141,850 |
| CHESS ROBERT | Director | 09/08/2021 | 110,400 |
| CHESS ROBERT | Director | 09/09/2021 | 164,670 |
| CHESS ROBERT | Director | 09/08/2021 | 128,000 |
| GREER R SCOTT | Director | 08/31/2021 | 571,500 |
| Zalevsky Jonathan | Chief R&D Officer | 08/16/2021 | 105,965 |
| Wilson Mark Andrew | SVP & General Counsel | 08/16/2021 | 26,415 |
| ROBIN HOWARD W | President & CEO | 08/16/2021 | 159,252 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2021 | 184,478 |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | 08/16/2021 | 85,635 |
| Labrucherie Gil M | SVP, COO & CFO | 08/17/2021 | 40,680 |
| Labrucherie Gil M | SVP, COO & CFO | 08/16/2021 | 108,801 |
| CHESS ROBERT | Director | 07/20/2021 | 29,063 |
| CHESS ROBERT | Director | 07/22/2021 | 1,256 |
| CHESS ROBERT | Director | 07/21/2021 | 48,631 |
| CHESS ROBERT | Director | 07/22/2021 | 1,529 |
| CHESS ROBERT | Director | 07/21/2021 | 59,238 |
| CHESS ROBERT | Director | 07/20/2021 | 35,381 |
| Labrucherie Gil M | SVP, COO & CFO | 05/17/2021 | 144,533 |
| CHESS ROBERT | Director | 05/12/2021 | 110,400 |
| CHESS ROBERT | Director | 05/12/2021 | 154,720 |
| CHESS ROBERT | Director | 04/14/2021 | 110,400 |
| CHESS ROBERT | Director | 04/14/2021 | 151,840 |
| Zalevsky Jonathan | Chief R&D Officer | 02/16/2021 | 540,034 |
| Wilson Mark Andrew | SVP & General Counsel | 02/16/2021 | 48,610 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/16/2021 | 261,841 |
| ROBIN HOWARD W | President & CEO | 02/16/2021 | 257,143 |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | 02/16/2021 | 343,558 |
| Labrucherie Gil M | SVP, COO & CFO | 02/16/2021 | 178,445 |
| Wilson Mark Andrew | SVP & General Counsel | 02/03/2021 | 47,027 |
| Wilson Mark Andrew | SVP & General Counsel | 02/03/2021 | 103,941 |
| ROBIN HOWARD W | President & CEO | 02/04/2021 | 1,320,000 |
| ROBIN HOWARD W | President & CEO | 02/03/2021 | 1,320,000 |
| ROBIN HOWARD W | President & CEO | 02/02/2021 | 1,320,000 |
| ROBIN HOWARD W | President & CEO | 02/04/2021 | 3,042,906 |
| ROBIN HOWARD W | President & CEO | 02/03/2021 | 2,958,000 |
| ROBIN HOWARD W | President & CEO | 02/02/2021 | 2,966,025 |
| Labrucherie Gil M | SVP, COO & CFO | 02/04/2021 | 440,000 |
| Labrucherie Gil M | SVP, COO & CFO | 02/03/2021 | 440,000 |
| Labrucherie Gil M | SVP, COO & CFO | 02/02/2021 | 440,000 |
| Labrucherie Gil M | SVP, COO & CFO | 02/04/2021 | 990,500 |
| Labrucherie Gil M | SVP, COO & CFO | 02/03/2021 | 980,500 |
| Labrucherie Gil M | SVP, COO & CFO | 02/02/2021 | 1,008,629 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 01/28/2021 | 660,000 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 01/28/2021 | 1,396,500 |
| GREER R SCOTT | Director | 01/05/2021 | 552,000 |
| Myriam Curet | Director | 12/15/2020 | 27,799 |
| Zalevsky Jonathan | Chief R&D Officer | 11/23/2020 | 268,632 |
| Zalevsky Jonathan | Chief R&D Officer | 11/16/2020 | 501,433 |
| Wilson Mark Andrew | SVP & General Counsel | 11/16/2020 | 26,055 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/16/2020 | 202,754 |
| ROBIN HOWARD W | President & CEO | 11/16/2020 | 202,737 |
| Labrucherie Gil M | SVP, COO & CFO | 11/16/2020 | 140,113 |
| Ajer Jeffrey Robert | Director | 09/28/2020 | 56,063 |
| CHESS ROBERT | Director | 09/25/2020 | 97,625 |
| Labrucherie Gil M | SVP, COO & CFO | 09/17/2020 | 39,920 |
| Ajer Jeffrey Robert | Director | 09/21/2020 | 44,415 |
| CHESS ROBERT | Director | 09/08/2020 | 73,920 |
| CHESS ROBERT | Director | 09/08/2020 | 148,240 |
| WHITFIELD ROY A | Director | 09/04/2020 | 277,200 |
| Zalevsky Jonathan | Chief R&D Officer | 08/17/2020 | 515,354 |
| Wilson Mark Andrew | SVP & General Counsel | 08/17/2020 | 30,075 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/17/2020 | 26,889 |
| ROBIN HOWARD W | President & CEO | 08/17/2020 | 233,778 |
| Labrucherie Gil M | SVP, COO & CFO | 08/18/2020 | 39,360 |
| Labrucherie Gil M | SVP, COO & CFO | 08/17/2020 | 122,839 |
| GREER R SCOTT | Director | 07/09/2020 | 369,600 |
| GREER R SCOTT | Director | 07/09/2020 | 375,225 |
| CHESS ROBERT | Director | 07/08/2020 | 73,920 |
| CHESS ROBERT | Director | 07/08/2020 | 196,640 |
| Zalevsky Jonathan | Chief R&D Officer | 05/18/2020 | 102,601 |
| Wilson Mark Andrew | SVP & General Counsel | 05/18/2020 | 34,418 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/18/2020 | 30,771 |
| ROBIN HOWARD W | President & CEO | 05/18/2020 | 201,870 |
| Labrucherie Gil M | SVP, COO & CFO | 05/18/2020 | 128,915 |
| Labrucherie Gil M | SVP, COO & CFO | 05/19/2020 | 45,240 |
| CHESS ROBERT | Director | 04/15/2020 | 73,920 |
| CHESS ROBERT | Director | 04/15/2020 | 147,010 |
| CHESS ROBERT | Director | 03/11/2020 | 73,920 |
| CHESS ROBERT | Director | 03/11/2020 | 134,316 |
| Zalevsky Jonathan | Chief R&D Officer | 02/18/2020 | 106,699 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/18/2020 | 31,156 |
| ROBIN HOWARD W | President & CEO | 02/18/2020 | 188,813 |
| Labrucherie Gil M | SVP, COO & CFO | 02/18/2020 | 132,714 |
| CHESS ROBERT | Director | 02/12/2020 | 73,920 |
| CHESS ROBERT | Director | 02/12/2020 | 188,000 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/06/2020 | 270,375 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/06/2020 | 854,250 |
| WHITFIELD ROY A | Director | 12/18/2019 | 92,400 |
| Zalevsky Jonathan | Chief R&D Officer | 11/18/2019 | 71,161 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/18/2019 | 48,753 |
| ROBIN HOWARD W | President & CEO | 11/18/2019 | 243,601 |
| Labrucherie Gil M | SVP, COO & CFO | 11/18/2019 | 159,268 |
| Labrucherie Gil M | SVP, COO & CFO | 11/13/2019 | 180,250 |
| Labrucherie Gil M | SVP, COO & CFO | 11/13/2019 | 494,750 |
| ROBIN HOWARD W | President & CEO | 10/15/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 10/17/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 10/16/2019 | 240,338 |
| ROBIN HOWARD W | President & CEO | 10/15/2019 | 565,085 |
| ROBIN HOWARD W | President & CEO | 10/17/2019 | 589,327 |
| ROBIN HOWARD W | President & CEO | 10/16/2019 | 582,678 |
| Labrucherie Gil M | SVP, COO & CFO | 10/15/2019 | 180,250 |
| Labrucherie Gil M | SVP, COO & CFO | 10/15/2019 | 395,750 |
| Lingnau Lutz | Director | 09/27/2019 | 53,520 |
| Ajer Jeffrey Robert | Director | 09/30/2019 | 42,892 |
| CHESS ROBERT | Director | 09/27/2019 | 71,960 |
| Ajer Jeffrey Robert | Director | 09/20/2019 | 45,540 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 09/16/2019 | 180,250 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 09/16/2019 | 513,000 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 09/05/2019 | 259,200 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/26/2019 | 489,300 |
| ROBIN HOWARD W | President & CEO | 08/23/2019 | 489,300 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2019 | 32,833 |
| ROBIN HOWARD W | President & CEO | 08/16/2019 | 227,801 |
| Nicholson John | SVP & Chief Operating Officer | 08/16/2019 | 69,315 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/16/2019 | 91,893 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 08/16/2019 | 58,897 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/14/2019 | 180,250 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/14/2019 | 444,750 |
| ROBIN HOWARD W | President & CEO | 07/24/2019 | 240,338 |
| ROBIN HOWARD W | President & CEO | 07/23/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 07/25/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 07/24/2019 | 1,070,355 |
| ROBIN HOWARD W | President & CEO | 07/23/2019 | 1,069,989 |
| ROBIN HOWARD W | President & CEO | 07/25/2019 | 988,323 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 07/10/2019 | 180,250 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 07/10/2019 | 864,250 |
| Lingnau Lutz | Director | 07/08/2019 | 92,400 |
| Lingnau Lutz | Director | 07/08/2019 | 346,300 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 06/17/2019 | 180,250 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 06/17/2019 | 842,750 |
| ROBIN HOWARD W | President & CEO | 05/22/2019 | 240,338 |
| ROBIN HOWARD W | President & CEO | 05/21/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 05/23/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 05/22/2019 | 1,112,689 |
| ROBIN HOWARD W | President & CEO | 05/21/2019 | 1,097,656 |
| ROBIN HOWARD W | President & CEO | 05/23/2019 | 1,089,656 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/16/2019 | 60,481 |
| ROBIN HOWARD W | President & CEO | 05/16/2019 | 419,825 |
| Nicholson John | SVP & Chief Operating Officer | 05/16/2019 | 127,895 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/16/2019 | 118,171 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 05/16/2019 | 76,825 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 05/16/2019 | 108,572 |
| GREER R SCOTT | Director | 03/08/2019 | 51,400 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/19/2019 | 76,641 |
| ROBIN HOWARD W | President & CEO | 02/20/2019 | 240,338 |
| ROBIN HOWARD W | President & CEO | 02/19/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 02/21/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 02/20/2019 | 1,440,029 |
| ROBIN HOWARD W | President & CEO | 02/19/2019 | 1,787,161 |
| ROBIN HOWARD W | President & CEO | 02/21/2019 | 1,366,986 |
| Nicholson John | SVP & Chief Operating Officer | 02/19/2019 | 162,015 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 02/19/2019 | 152,265 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 02/19/2019 | 101,143 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 02/19/2019 | 140,311 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/04/2019 | 172,312 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/04/2019 | 679,577 |
| Nicholson John | SVP & Chief Operating Officer | 01/28/2019 | 673,470 |
| Nicholson John | SVP & Chief Operating Officer | 01/28/2019 | 2,697,660 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/16/2018 | 153,612 |
| ROBIN HOWARD W | President & CEO | 11/16/2018 | 586,220 |
| Nicholson John | SVP & Chief Operating Officer | 11/16/2018 | 228,812 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 11/16/2018 | 249,199 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/16/2018 | 179,546 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/16/2018 | 173,043 |
| Lingnau Lutz | Director | 09/20/2018 | 512,820 |
| CHESS ROBERT | Director | 09/19/2018 | 255,645 |
| Ajer Jeffrey Robert | Director | 09/20/2018 | 383,130 |
| GREER R SCOTT | Director | 09/04/2018 | 51,400 |
| GREER R SCOTT | Director | 09/04/2018 | 673,900 |
| WINGER DENNIS L | Director | 08/17/2018 | 213,900 |
| WINGER DENNIS L | Director | 08/21/2018 | 213,900 |
| WINGER DENNIS L | Director | 08/21/2018 | 904,500 |
| WINGER DENNIS L | Director | 08/17/2018 | 894,300 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2018 | 285,167 |
| Nicholson John | SVP & Chief Operating Officer | 08/16/2018 | 475,201 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/16/2018 | 479,289 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 08/16/2018 | 347,246 |
| ROBIN HOWARD W | President & CEO | 08/14/2018 | 427,600 |
| ROBIN HOWARD W | President & CEO | 08/16/2018 | 1,190,718 |
| ROBIN HOWARD W | President & CEO | 08/14/2018 | 2,403,200 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 08/16/2018 | 391,338 |
| WINGER DENNIS L | Director | 08/14/2018 | 1,030,069 |
| WINGER DENNIS L | Director | 08/13/2018 | 1,045,310 |
| ROBIN HOWARD W | President & CEO | 06/27/2018 | 463,230 |
| ROBIN HOWARD W | President & CEO | 06/26/2018 | 463,230 |
| ROBIN HOWARD W | President & CEO | 06/25/2018 | 463,240 |
| ROBIN HOWARD W | President & CEO | 06/26/2018 | 2,138,917 |
| ROBIN HOWARD W | President & CEO | 06/25/2018 | 2,245,568 |
| ROBIN HOWARD W | President & CEO | 06/27/2018 | 2,053,551 |
| WHITFIELD ROY A | Director | 06/06/2018 | 201,860 |
| WHITFIELD ROY A | Director | 06/05/2018 | 88,352 |
| CHESS ROBERT | Director | 06/05/2018 | 142,600 |
| CHESS ROBERT | Director | 06/05/2018 | 551,600 |
| GREER R SCOTT | Director | 06/06/2018 | 44,204 |
| GREER R SCOTT | Director | 06/04/2018 | 7,196 |
| GREER R SCOTT | Director | 06/06/2018 | 516,000 |
| GREER R SCOTT | Director | 06/04/2018 | 86,786 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/16/2018 | 298,203 |
| ROBIN HOWARD W | President & CEO | 05/16/2018 | 1,066,641 |
| Nicholson John | SVP & Chief Operating Officer | 05/16/2018 | 410,029 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/16/2018 | 412,030 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 05/16/2018 | 338,563 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 05/16/2018 | 286,445 |
| CHESS ROBERT | Director | 05/03/2018 | 219,700 |
| CHESS ROBERT | Director | 05/03/2018 | 2,070,050 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/03/2018 | 320,700 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/02/2018 | 320,700 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/01/2018 | 320,700 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/03/2018 | 2,485,800 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/02/2018 | 2,568,900 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/01/2018 | 2,509,500 |
| ROBIN HOWARD W | President & CEO | 05/03/2018 | 463,230 |
| ROBIN HOWARD W | President & CEO | 05/02/2018 | 463,230 |
| ROBIN HOWARD W | President & CEO | 05/01/2018 | 463,240 |
| ROBIN HOWARD W | President & CEO | 05/03/2018 | 3,590,572 |
| ROBIN HOWARD W | President & CEO | 05/02/2018 | 3,710,605 |
| ROBIN HOWARD W | President & CEO | 05/01/2018 | 3,624,889 |
| WHITFIELD ROY A | Director | 04/17/2018 | 427,800 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 04/16/2018 | 148,388 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 04/16/2018 | 1,408,366 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/10/2018 | 3,619 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/10/2018 | 53,046 |
| Lingnau Lutz | Director | 04/05/2018 | 277,200 |
| Lingnau Lutz | Director | 04/05/2018 | 3,052,200 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/09/2018 | 68,481 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/05/2018 | 144,200 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/09/2018 | 997,765 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/05/2018 | 2,035,000 |
| GREER R SCOTT | Director | 04/06/2018 | 427,800 |
| GREER R SCOTT | Director | 04/06/2018 | 2,766,600 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/09/2018 | 356,895 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/06/2018 | 1,005,505 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/09/2018 | 4,758,435 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/06/2018 | 10,131,745 |
| CHESS ROBERT | Director | 04/06/2018 | 219,700 |
| CHESS ROBERT | Director | 04/06/2018 | 2,303,600 |
| KUEBLER CHRISTOPHER A | Director | 03/07/2018 | 233,236 |
| KUEBLER CHRISTOPHER A | Director | 03/06/2018 | 13,364 |
| KUEBLER CHRISTOPHER A | Director | 03/07/2018 | 3,643,134 |
| KUEBLER CHRISTOPHER A | Director | 03/06/2018 | 260,780 |
| Nicholson John | SVP & Chief Operating Officer | 03/07/2018 | 10,059,464 |
| Nicholson John | SVP & Chief Operating Officer | 03/06/2018 | 11,794,800 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/16/2018 | 211,082 |
| ROBIN HOWARD W | President & CEO | 02/16/2018 | 1,060,637 |
| Nicholson John | SVP & Chief Operating Officer | 02/16/2018 | 404,664 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 02/16/2018 | 288,382 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 02/16/2018 | 238,453 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 02/16/2018 | 201,212 |
| Nicholson John | SVP & Chief Operating Officer | 01/31/2018 | 1,360,800 |
| ROBIN HOWARD W | President & CEO | 01/22/2018 | 944,996 |
| ROBIN HOWARD W | President & CEO | 01/22/2018 | 6,318,308 |
| WINGER DENNIS L | Director | 01/04/2018 | 403,988 |
| KUEBLER CHRISTOPHER A | Director | 01/02/2018 | 427,800 |
| KUEBLER CHRISTOPHER A | Director | 01/02/2018 | 1,759,800 |
| ROBIN HOWARD W | President & CEO | 12/13/2017 | 944,996 |
| ROBIN HOWARD W | President & CEO | 12/13/2017 | 4,640,815 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/16/2017 | 233,932 |
| ROBIN HOWARD W | President & CEO | 11/16/2017 | 799,192 |
| Nicholson John | SVP & Chief Operating Officer | 11/16/2017 | 292,803 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 11/16/2017 | 296,253 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/16/2017 | 247,555 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 11/16/2017 | 222,123 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/16/2017 | 211,508 |
| Nicholson John | SVP & Chief Operating Officer | 11/13/2017 | 231,000 |
| Nicholson John | SVP & Chief Operating Officer | 11/13/2017 | 601,080 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/07/2017 | 626,260 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/06/2017 | 54,701 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/06/2017 | 128,283 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/07/2017 | 718,648 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/06/2017 | 199,310 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/08/2017 | 2,859,000 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/06/2017 | 522,432 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/08/2017 | 9,027,000 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/07/2017 | 1,944,044 |
| ROBIN HOWARD W | President & CEO | 11/01/2017 | 945,008 |
| ROBIN HOWARD W | President & CEO | 11/01/2017 | 1,964,182 |
| ROBIN HOWARD W | President & CEO | 10/09/2017 | 944,996 |
| ROBIN HOWARD W | President & CEO | 10/09/2017 | 2,016,659 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 10/05/2017 | 81,062 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 10/05/2017 | 189,575 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 10/05/2017 | 416,242 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 10/05/2017 | 1,090,615 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 10/02/2017 | 1,360,800 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 10/02/2017 | 2,934,000 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 10/02/2017 | 626,012 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 09/29/2017 | 477,988 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 10/02/2017 | 1,372,804 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 09/29/2017 | 1,040,836 |
| Lingnau Lutz | Director | 09/22/2017 | 109,850 |
| KUEBLER CHRISTOPHER A | Director | 09/22/2017 | 87,440 |
| CHESS ROBERT | Director | 09/21/2017 | 139,008 |
| ROBIN HOWARD W | President & CEO | 09/06/2017 | 944,996 |
| ROBIN HOWARD W | President & CEO | 09/06/2017 | 1,794,993 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2017 | 51,159 |
| ROBIN HOWARD W | President & CEO | 08/16/2017 | 945,008 |
| ROBIN HOWARD W | President & CEO | 08/16/2017 | 1,766,081 |
| Nicholson John | SVP & Chief Operating Officer | 08/16/2017 | 61,380 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/16/2017 | 61,380 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 08/16/2017 | 57,110 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 08/16/2017 | 38,582 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 08/16/2017 | 32,863 |
| WHITFIELD ROY A | Director | 08/10/2017 | 628,250 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/18/2017 | 606,317 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/18/2017 | 1,158,812 |
| Lingnau Lutz | Director | 07/14/2017 | 427,800 |
| Lingnau Lutz | Director | 07/14/2017 | 622,800 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/11/2017 | 92,615 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/12/2017 | 405,069 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/11/2017 | 176,505 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/12/2017 | 773,813 |
| Krivulka Joseph J | Director | 06/26/2017 | 125,550 |
| Nicholson John | SVP & Chief Operating Officer | 06/07/2017 | 951,000 |
| Nicholson John | SVP & Chief Operating Officer | 06/07/2017 | 1,956,708 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/16/2017 | 51,827 |
| ROBIN HOWARD W | President & CEO | 05/16/2017 | 163,985 |
| Nicholson John | SVP & Chief Operating Officer | 05/16/2017 | 61,504 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/16/2017 | 62,149 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 05/16/2017 | 57,848 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 05/16/2017 | 28,347 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 05/16/2017 | 33,255 |
| CHESS ROBERT | Director | 05/15/2017 | 41,850 |
| CHESS ROBERT | Director | 05/15/2017 | 98,950 |
| CHESS ROBERT | Director | 04/17/2017 | 41,850 |
| CHESS ROBERT | Director | 04/17/2017 | 93,600 |
| Lingnau Lutz | Director | 04/07/2017 | 140,350 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/05/2017 | 953,000 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/05/2017 | 2,170,000 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/05/2017 | 2,466,000 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/05/2017 | 3,906,000 |
| KUEBLER CHRISTOPHER A | Director | 04/05/2017 | 125,550 |
| KUEBLER CHRISTOPHER A | Director | 04/05/2017 | 328,200 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 03/20/2017 | 1,120,875 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 03/20/2017 | 2,215,125 |
| WHITFIELD ROY A | Director | 03/15/2017 | 117,180 |
| CHESS ROBERT | Director | 03/14/2017 | 41,850 |
| CHESS ROBERT | Director | 03/14/2017 | 77,050 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 03/03/2017 | 278,512 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 03/02/2017 | 1,061,988 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 03/03/2017 | 494,234 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 03/02/2017 | 2,537,716 |
| Lingnau Lutz | Director | 02/21/2017 | 154,200 |
| Lingnau Lutz | Director | 02/21/2017 | 392,400 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/16/2017 | 25,820 |
| ROBIN HOWARD W | President & CEO | 02/16/2017 | 113,477 |
| Nicholson John | SVP & Chief Operating Officer | 02/16/2017 | 42,534 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 02/16/2017 | 30,997 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 02/16/2017 | 28,842 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 02/16/2017 | 19,145 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 02/16/2017 | 16,570 |
| Nicholson John | SVP & Chief Operating Officer | 02/10/2017 | 209,250 |
| ROBIN HOWARD W | President & CEO | 02/08/2017 | 406,875 |
| ROBIN HOWARD W | President & CEO | 02/08/2017 | 1,141,000 |
| Nicholson John | SVP & Chief Operating Officer | 02/03/2017 | 39,548 |
| Nicholson John | SVP & Chief Operating Officer | 02/02/2017 | 309,202 |
| Nicholson John | SVP & Chief Operating Officer | 02/02/2017 | 823,208 |
| Nicholson John | SVP & Chief Operating Officer | 02/03/2017 | 106,142 |
| ROBIN HOWARD W | President & CEO | 01/17/2017 | 406,875 |
| ROBIN HOWARD W | President & CEO | 01/17/2017 | 1,080,625 |
| ROBIN HOWARD W | President & CEO | 12/07/2016 | 406,875 |
| ROBIN HOWARD W | President & CEO | 12/07/2016 | 1,071,000 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/16/2016 | 27,725 |
| ROBIN HOWARD W | President & CEO | 11/17/2016 | 406,875 |
| ROBIN HOWARD W | President & CEO | 11/17/2016 | 1,213,625 |
| ROBIN HOWARD W | President & CEO | 11/16/2016 | 83,174 |
| Nicholson John | SVP & Chief Operating Officer | 11/16/2016 | 23,090 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 11/16/2016 | 23,090 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/16/2016 | 23,090 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 11/16/2016 | 11,838 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/16/2016 | 9,353 |
| GREER R SCOTT | Director | 10/24/2016 | 202,500 |
| ROBIN HOWARD W | President & CEO | 10/04/2016 | 406,875 |
| ROBIN HOWARD W | President & CEO | 10/04/2016 | 1,492,750 |
| WHITFIELD ROY A | Director | 09/23/2016 | 239,820 |
| Lingnau Lutz | Director | 09/15/2016 | 171,540 |
| KUEBLER CHRISTOPHER A | Director | 09/16/2016 | 143,475 |
| CHESS ROBERT | Director | 09/15/2016 | 230,520 |
| ROBIN HOWARD W | President & CEO | 09/01/2016 | 406,875 |
| ROBIN HOWARD W | President & CEO | 09/01/2016 | 1,560,125 |
| Nicholson John | SVP & Chief Operating Officer | 08/16/2016 | 58,247 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2016 | 69,731 |
| ROBIN HOWARD W | President & CEO | 08/16/2016 | 207,507 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/16/2016 | 58,036 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 08/16/2016 | 58,036 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 08/16/2016 | 29,589 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 08/16/2016 | 23,460 |
| CHESS ROBERT | Director | 08/01/2016 | 25,750 |
| CHESS ROBERT | Director | 08/01/2016 | 86,300 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 07/11/2016 | 465,000 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 07/11/2016 | 1,509,000 |
| CHESS ROBERT | Director | 07/01/2016 | 25,750 |
| CHESS ROBERT | Director | 07/01/2016 | 70,500 |
| CHESS ROBERT | Director | 06/01/2016 | 25,750 |
| CHESS ROBERT | Director | 06/01/2016 | 77,500 |
| Nicholson John | SVP & Chief Financial Officer | 05/16/2016 | 0 |
| Nicholson John | SVP & Chief Financial Officer | 05/17/2016 | 11,624 |
| ROBIN HOWARD W | President & CEO | 05/16/2016 | 1 |
| ROBIN HOWARD W | President & CEO | 05/17/2016 | 29,469 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 05/16/2016 | 0 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 05/17/2016 | 4,604 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 05/16/2016 | 0 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 05/17/2016 | 5,867 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 05/16/2016 | 0 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 05/17/2016 | 11,339 |
| Labrucherie Gil M | SVP & General Counsel | 05/16/2016 | 0 |
| Labrucherie Gil M | SVP & General Counsel | 05/17/2016 | 11,353 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/16/2016 | 0 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/17/2016 | 9,832 |
| Lingnau Lutz | Director | 04/25/2016 | 125,550 |
| Lingnau Lutz | Director | 04/25/2016 | 244,050 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 03/09/2016 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 03/09/2016 | 176,850 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 02/16/2016 | 0 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 02/17/2016 | 6,628 |
| Nicholson John | SVP & Chief Financial Officer | 02/16/2016 | 0 |
| Nicholson John | SVP & Chief Financial Officer | 02/17/2016 | 11,479 |
| ROBIN HOWARD W | President & CEO | 02/16/2016 | 1 |
| ROBIN HOWARD W | President & CEO | 02/17/2016 | 25,592 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 02/16/2016 | 0 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 02/17/2016 | 4,649 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/16/2016 | 0 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/17/2016 | 8,535 |
| Labrucherie Gil M | SVP & General Counsel | 02/16/2016 | 0 |
| Labrucherie Gil M | SVP & General Counsel | 02/17/2016 | 9,858 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 02/16/2016 | 0 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 02/17/2016 | 11,479 |
| Labrucherie Gil M | SVP & General Counsel | 02/10/2016 | 75,362 |
| Labrucherie Gil M | SVP & General Counsel | 02/10/2016 | 134,042 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/10/2016 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/10/2016 | 172,350 |
| ROBIN HOWARD W | President & CEO | 02/10/2016 | 430,662 |
| ROBIN HOWARD W | President & CEO | 02/10/2016 | 765,992 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 01/19/2016 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 01/19/2016 | 211,800 |
| ROBIN HOWARD W | President & CEO | 01/19/2016 | 430,669 |
| ROBIN HOWARD W | President & CEO | 01/19/2016 | 941,338 |
| Lingnau Lutz | Director | 01/20/2016 | 77,250 |
| Lingnau Lutz | Director | 01/20/2016 | 217,650 |
| Labrucherie Gil M | SVP & General Counsel | 01/19/2016 | 75,369 |
| Labrucherie Gil M | SVP & General Counsel | 01/19/2016 | 164,738 |
| Labrucherie Gil M | SVP & General Counsel | 12/03/2015 | 308,040 |
| Labrucherie Gil M | SVP & General Counsel | 12/03/2015 | 714,166 |
| ROBIN HOWARD W | President & CEO | 12/03/2015 | 837,840 |
| ROBIN HOWARD W | President & CEO | 12/03/2015 | 1,983,766 |
| KUEBLER CHRISTOPHER A | Director | 12/04/2015 | 77,250 |
| KUEBLER CHRISTOPHER A | Director | 12/04/2015 | 237,300 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 12/03/2015 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 12/03/2015 | 238,050 |
| WANG SUSAN | Director | 11/19/2015 | 77,758 |
| WANG SUSAN | Director | 11/18/2015 | 153,162 |
| WANG SUSAN | Director | 11/20/2015 | 418,430 |
| WANG SUSAN | Director | 11/18/2015 | 305,580 |
| WANG SUSAN | Director | 11/20/2015 | 743,490 |
| WANG SUSAN | Director | 11/19/2015 | 227,223 |
| ROBIN HOWARD W | President & CEO | 11/11/2015 | 837,833 |
| ROBIN HOWARD W | President & CEO | 11/11/2015 | 1,690,000 |
| Labrucherie Gil M | SVP & General Counsel | 11/11/2015 | 308,033 |
| Labrucherie Gil M | SVP & General Counsel | 11/11/2015 | 608,400 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/11/2015 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/11/2015 | 202,800 |
| Lingnau Lutz | Director | 10/28/2015 | 83,125 |
| Lingnau Lutz | Director | 10/28/2015 | 150,000 |
| GREER R SCOTT | Director | 10/15/2015 | 368,550 |
| ROBIN HOWARD W | President & CEO | 10/06/2015 | 837,833 |
| ROBIN HOWARD W | President & CEO | 10/06/2015 | 1,373,750 |
| Labrucherie Gil M | SVP & General Counsel | 10/06/2015 | 308,033 |
| Labrucherie Gil M | SVP & General Counsel | 10/06/2015 | 494,550 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 10/06/2015 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 10/06/2015 | 164,850 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 09/23/2015 | 66,500 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 09/23/2015 | 130,400 |
| ROBIN HOWARD W | President & CEO | 09/23/2015 | 837,827 |
| ROBIN HOWARD W | President & CEO | 09/23/2015 | 1,629,987 |
| Labrucherie Gil M | SVP & General Counsel | 09/23/2015 | 308,027 |
| Labrucherie Gil M | SVP & General Counsel | 09/23/2015 | 586,787 |
| WHITFIELD ROY A | Director | 09/11/2015 | 132,150 |
| Labrucherie Gil M | SVP & General Counsel | 08/13/2015 | 232,664 |
| Labrucherie Gil M | SVP & General Counsel | 08/13/2015 | 362,996 |
| ROBIN HOWARD W | President & CEO | 08/13/2015 | 407,164 |
| ROBIN HOWARD W | President & CEO | 08/13/2015 | 635,246 |
| Nicholson John | SVP & Chief Financial Officer | 08/11/2015 | 2,437,100 |
| Nicholson John | SVP & Chief Financial Officer | 08/12/2015 | 584,000 |
| Nicholson John | SVP & Chief Financial Officer | 08/12/2015 | 733,325 |
| Nicholson John | SVP & Chief Financial Officer | 08/11/2015 | 2,716,089 |
| Krivulka Joseph J | Director | 07/24/2015 | 132,150 |
| ROBIN HOWARD W | President & CEO | 07/14/2015 | 407,171 |
| ROBIN HOWARD W | President & CEO | 07/14/2015 | 687,175 |
| Labrucherie Gil M | SVP & General Counsel | 07/14/2015 | 232,671 |
| Labrucherie Gil M | SVP & General Counsel | 07/14/2015 | 392,675 |
| WANG SUSAN | Director | 06/29/2015 | 209,400 |
| WANG SUSAN | Director | 06/29/2015 | 381,000 |
| CHESS ROBERT | Director | 06/19/2015 | 132,150 |
| CHESS ROBERT | Director | 06/19/2015 | 177,150 |
| Lingnau Lutz | Director | 06/15/2015 | 166,250 |
| Lingnau Lutz | Director | 06/15/2015 | 278,750 |
| KUEBLER CHRISTOPHER A | Director | 01/13/2015 | 132,150 |
| KUEBLER CHRISTOPHER A | Director | 01/13/2015 | 240,000 |
| CHESS ROBERT | Director | 12/29/2014 | 449,580 |
| CHESS ROBERT | Director | 12/29/2014 | 452,530 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 12/22/2014 | 56,900 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 12/22/2014 | 77,800 |
| Labrucherie Gil M | SVP & General Counsel | 12/01/2014 | 139,500 |
| Labrucherie Gil M | SVP & General Counsel | 11/28/2014 | 418,500 |
| Labrucherie Gil M | SVP & General Counsel | 12/01/2014 | 510,000 |
| Labrucherie Gil M | SVP & General Counsel | 11/28/2014 | 1,531,800 |
| ROBIN HOWARD W | President & CEO | 11/28/2014 | 983,789 |
| ROBIN HOWARD W | President & CEO | 12/01/2014 | 1,459,211 |
| ROBIN HOWARD W | President & CEO | 12/01/2014 | 3,553,952 |
| ROBIN HOWARD W | President & CEO | 11/28/2014 | 2,398,867 |
| Labrucherie Gil M | SVP & General Counsel | 11/24/2014 | 136,710 |
| Labrucherie Gil M | SVP & General Counsel | 11/24/2014 | 157,920 |
| ROBIN HOWARD W | President & CEO | 11/24/2014 | 1,928,256 |
| ROBIN HOWARD W | President & CEO | 11/25/2014 | 6,783,744 |
| ROBIN HOWARD W | President & CEO | 11/25/2014 | 7,152,832 |
| ROBIN HOWARD W | President & CEO | 11/24/2014 | 1,994,656 |
| Lingnau Lutz | Director | 11/24/2014 | 132,150 |
| Lingnau Lutz | Director | 11/24/2014 | 225,300 |
| Labrucherie Gil M | SVP & General Counsel | 11/03/2014 | 112,662 |
| Labrucherie Gil M | SVP & General Counsel | 11/03/2014 | 136,422 |
| KUEBLER CHRISTOPHER A | Director | 08/05/2013 | 142,625 |
| KUEBLER CHRISTOPHER A | Director | 08/05/2013 | 155,125 |
| WHITFIELD ROY A | Director | 08/05/2013 | 142,625 |
| WHITFIELD ROY A | Director | 08/05/2013 | 155,125 |
| KUEBLER CHRISTOPHER A | Director | 09/27/2012 | 108,250 |
| KUEBLER CHRISTOPHER A | Director | 09/27/2012 | 133,250 |
| WINGER DENNIS L | Director | 09/14/2012 | 45,908 |
| CHESS ROBERT | Director | 07/13/2012 | 146,886 |
| CHESS ROBERT | Director | 07/13/2012 | 204,009 |
| CHESS ROBERT | Director | 03/08/2011 | 40,500 |
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FUNDS WITH A POSITION IN NEKTAR THERAPEUTICS
| Fund | # Shares Owned | % of Portfolio | % Change | Investing Style |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 18,700,000 | 0.22% | New | Other |
| D. E. SHAW & CO., INC. | 6,123,024 | 0.00381% | -33.1% | Other |
| BLACKROCK INC. | 7,684,629 | 0.00013% | -10.69% | Other |
| RENAISSANCE TECHNOLOGIES LLC | 3,506,681 | 0.00356% | -14.3% | Other |
| AQR CAPITAL MANAGEMENT LLC | 3,666,264 | 0.00451% | 29.93% | Other |
| GEODE CAPITAL MANAGEMENT, LLC | 1,955,356 | 0.00014% | 3.13% | Other |
| UBS OCONNOR LLC | 1,376,249 | 0.02% | New | Value |
| BALYASNY ASSET MANAGEMENT L.P. | 1,333,668 | 0.00162% | 2899.03% | Event Driven |
| ORBIMED ADVISORS LLC | 515,000 (Call) | 0.00537% | Exited | Other |
| TUDOR INVESTMENT CORP ET AL | 57,083 | 0.00034% | No change | Event Driven, Other |
CHANGE IN SHARES OUTSTANDING FOR NEKTAR THERAPEUTICS
STOCK BUYBACKS FOR NEKTAR THERAPEUTICS
Period of Report
Previous Period
% Change in Shares
10-K/10-Q Filings
Quarter
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Period of Report: 06/30/2023
10-K/10-Q Filings: View
Previous Period
% Change in Shares
Quarter
03/31/2023
0.41%
1Q
12/31/2022
0.75%
2Q
09/30/2022
1.07%
3Q
06/30/2022
1.53%
4Q
03/31/2022
2.05%
5Q
12/31/2021
2.53%
6Q
09/30/2021
3.01%
7Q
06/30/2021
3.81%
8Q
03/31/2021