Nektar Therapeutics (NKTR) NASDAQ
$1.25 - (-)
Market Cap: $230.10M
As of 09/12/24 04:00 PM EDT. Market closed.
Nektar Therapeutics (NKTR)
NASDAQ
$1.25
- (-)
Market Cap: $230.10M
As of 09/12/24 04:00 PM EDT. Market closed.
Add to Portfolio
Nektar Therapeutics, a biopharmaceutical company, focuses on discovering and developing medicines in areas of unmet medical need in the United States and internationally. The company's products include Bempegaldesleukin, a CD122-preferential interleukin-2 (IL-2) pathway agonist, which is in phase 3 clinical trial to treat metastatic melanoma, renal cell carcinoma, muscle-invasive bladder cancer, ... read more
COMPANY PROFILE
Sector
Healthcare
Industry
Biotechnology
CEO
Mr. Howard W. Robin
Full Time Employees
137
CEO Compensation (Base)
$1.08M
CEO Compensation (Total)
$3.14M
Sector
Healthcare
Industry
Biotechnology
CEO
Mr. Howard W. Robin
Full Time Employees
137
CEO Compensation (Base)
$1.08M
CEO Compensation (Total)
$3.14M
URL
Address
455 Mission Bay Boulevard South, CA, San Francisco, 94158.
PRICE CHART FOR NEKTAR THERAPEUTICS
From:
To:
NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
$1.25
Previous Close
$1.25
Days Range
$1.21 - $1.27
52 week range
$0.41 - $1.93
Volume
441,883
Avg. Volume (30 days)
1,574,085
Market Cap
$230.10M
Dividend Yield
-
P/E
(1.39)
Shares Outstanding
184,079,000
Open
$1.25
Previous Close
$1.25
Days Range
$1.21 - $1.27
52 week range
$0.41 - $1.93
Volume
441,883
Avg. Volume (30 days)
1,574,085
Market Cap
$230.10M
Dividend Yield
-
P/E
(1.39)
Shares Outstanding
184,079,000
FINANCIAL STATEMENTS FOR NEKTAR THERAPEUTICS
LOADING...
Open in: 
Open in:
INSIDER TRANSACTIONS FOR NEKTAR THERAPEUTICS
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| Zalevsky Jonathan | Chief R&D Officer | Aug 19, 2024 | Sale | $1.28 | 6,866 | 8,788 | 250,804 | Aug 20, 2024, 09:15 PM |
| Wilson Mark Andrew | Chief Legal Officer | Aug 19, 2024 | Sale | $1.28 | 5,651 | 7,233 | 225,263 | Aug 20, 2024, 09:15 PM |
| ROBIN HOWARD W | President & CEO | Aug 19, 2024 | Sale | $1.28 | 14,881 | 19,048 | 848,358 | Aug 20, 2024, 09:14 PM |
| CHESS ROBERT | Director | Jun 14, 2024 | Sale | $1.20 | 19,500 | 23,400 | 255,273 | Jun 14, 2024, 06:02 PM |
| ROBIN HOWARD W | President & CEO | May 17, 2024 | Sale | $1.75 | 16,650 | 29,138 | 863,239 | May 20, 2024, 09:14 PM |
| Zalevsky Jonathan | Chief R&D Officer | May 17, 2024 | Sale | $1.75 | 7,355 | 12,871 | 257,670 | May 20, 2024, 09:13 PM |
| Wilson Mark Andrew | Chief Legal Officer | May 17, 2024 | Sale | $1.75 | 6,260 | 10,955 | 230,414 | May 20, 2024, 09:12 PM |
| Deep Track Capital, LP | 10% Owner | May 10, 2024 | Sale | $1.78 | 56,000 | 99,630 | 18,344,000 | May 13, 2024, 04:36 PM |
| Zalevsky Jonathan | Chief R&D Officer | Feb 20, 2024 | Sale | $0.68 | 9,014 | 6,130 | 265,025 | Feb 22, 2024, 08:19 PM |
| Wilson Mark Andrew | Chief Legal Officer | Feb 20, 2024 | Sale | $0.68 | 7,606 | 5,172 | 236,674 | Feb 22, 2024, 08:17 PM |
| ROBIN HOWARD W | President & CEO | Feb 20, 2024 | Sale | $0.68 | 20,033 | 13,622 | 879,889 | Feb 22, 2024, 08:16 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 17, 2023 | Sale | $0.49 | 9,646 | 4,727 | 274,039 | Nov 20, 2023, 09:02 PM |
| Wilson Mark Andrew | Chief Legal Officer | Nov 17, 2023 | Sale | $0.49 | 7,179 | 3,518 | 243,780 | Nov 20, 2023, 09:00 PM |
| ROBIN HOWARD W | President & CEO | Nov 17, 2023 | Sale | $0.49 | 19,877 | 9,740 | 899,922 | Nov 20, 2023, 08:58 PM |
| Curet Myriam | Director | Sep 18, 2023 | Sale | $0.69 | 4,359 | 3,008 | 27,418 | Sep 20, 2023, 08:09 PM |
| CHESS ROBERT | Director | Sep 22, 2022 | Sale | $0.67 | 10,200 | 6,834 | 274,773 | Sep 20, 2023, 08:08 PM |
| Ajer Jeffrey Robert | Director | Sep 18, 2023 | Sale | $0.69 | 4,359 | 3,008 | 34,153 | Sep 20, 2023, 08:06 PM |
| Zalevsky Jonathan | Chief R&D Officer | Aug 16, 2023 | Sale | $0.78 | 9,703 | 7,568 | 283,685 | Aug 17, 2023, 08:08 PM |
| Wilson Mark Andrew | Chief Legal Officer | Aug 16, 2023 | Sale | $0.78 | 7,221 | 5,632 | 250,959 | Aug 17, 2023, 08:07 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2023 | Sale | $0.78 | 19,998 | 15,598 | 919,799 | Aug 17, 2023, 08:06 PM |
| WHITFIELD ROY A | Director | Jun 14, 2023 | Sale | $0.57 | 30,000 | 17,100 | 216,250 | Jun 15, 2023, 06:26 PM |
| Zalevsky Jonathan | Chief R&D Officer | May 16, 2023 | Sale | $0.72 | 9,791 | 7,050 | 293,388 | May 17, 2023, 08:29 PM |
| Wilson Mark Andrew | Chief Legal Officer | May 16, 2023 | Sale | $0.72 | 7,543 | 5,431 | 257,680 | May 17, 2023, 08:28 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2023 | Sale | $0.72 | 20,361 | 14,660 | 939,797 | May 17, 2023, 08:27 PM |
| Zalevsky Jonathan | Chief R&D Officer | Feb 16, 2023 | Sale | $3.00 | 10,484 | 31,452 | 303,179 | Feb 17, 2023, 09:00 PM |
| Wilson Mark Andrew | Chief Legal Officer | Feb 16, 2023 | Sale | $3.00 | 8,275 | 24,825 | 265,223 | Feb 17, 2023, 08:59 PM |
| Thomsen Jillian B. | Chief Financial Officer | Feb 16, 2023 | Sale | $3.00 | 10,267 | 30,801 | 313,497 | Feb 17, 2023, 08:58 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2023 | Sale | $3.00 | 19,635 | 58,905 | 960,158 | Feb 17, 2023, 08:57 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 16, 2022 | Sale | $3.57 | 13,460 | 48,052 | 313,663 | Nov 18, 2022, 06:05 PM |
| Wilson Mark Andrew | Chief Legal Officer | Nov 16, 2022 | Sale | $3.57 | 8,690 | 31,023 | 272,498 | Nov 18, 2022, 06:04 PM |
| Thomsen Jillian B. | Chief Financial Officer | Nov 16, 2022 | Sale | $3.57 | 11,095 | 39,609 | 323,764 | Nov 18, 2022, 06:03 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2022 | Sale | $3.57 | 38,014 | 135,710 | 979,793 | Nov 18, 2022, 06:02 PM |
| Curet Myriam | Director | Sep 23, 2022 | Sale | $3.16 | 4,198 | 13,266 | 31,777 | Sep 26, 2022, 07:32 PM |
| Ajer Jeffrey Robert | Director | Sep 23, 2022 | Sale | $3.16 | 4,198 | 13,266 | 38,512 | Sep 26, 2022, 07:25 PM |
| CHESS ROBERT | Director | Sep 22, 2022 | Sale | $3.19 | 5,100 | 16,269 | 228,179 | Sep 26, 2022, 07:23 PM |
| EASTHAM KARIN | Director | Sep 13, 2022 | Sale | $3.61 | 21,267 | 76,774 | 13,033 | Sep 14, 2022, 06:01 PM |
| Zalevsky Jonathan | Chief R&D Officer | Aug 18, 2022 | Sale | $4.65 | 73,716 | 342,779 | 327,123 | Aug 19, 2022, 06:27 PM |
| Zalevsky Jonathan | Chief R&D Officer | Aug 16, 2022 | Sale | $4.76 | 10,560 | 50,266 | 400,839 | Aug 17, 2022, 07:41 PM |
| Wilson Mark Andrew | SVP & General Counsel | Aug 16, 2022 | Sale | $4.76 | 3,189 | 15,180 | 281,188 | Aug 17, 2022, 07:40 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2022 | Sale | $4.76 | 2,006 | 9,549 | 334,859 | Aug 17, 2022, 07:40 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2022 | Sale | $4.76 | 13,759 | 65,493 | 1,017,807 | Aug 17, 2022, 07:39 PM |
| Zalevsky Jonathan | Chief R&D Officer | May 16, 2022 | Sale | $3.95 | 21,673 | 85,608 | 276,399 | May 17, 2022, 09:40 PM |
| Wilson Mark Andrew | SVP & General Counsel | May 16, 2022 | Sale | $3.95 | 3,136 | 12,387 | 117,939 | May 17, 2022, 09:38 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 16, 2022 | Sale | $3.95 | 5,841 | 23,072 | 170,427 | May 17, 2022, 09:36 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2022 | Sale | $3.95 | 36,529 | 144,290 | 620,941 | May 17, 2022, 09:35 PM |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | May 16, 2022 | Sale | $3.95 | 4,592 | 18,138 | 223,210 | May 17, 2022, 09:33 PM |
| Labrucherie Gil M | SVP, COO & CFO | May 16, 2022 | Sale | $3.95 | 17,448 | 68,920 | 312,905 | May 17, 2022, 09:32 PM |
| Zalevsky Jonathan | Chief R&D Officer | Feb 16, 2022 | Sale | $10.95 | 10,912 | 119,486 | 274,122 | Feb 18, 2022, 06:20 PM |
| Wilson Mark Andrew | SVP & General Counsel | Feb 16, 2022 | Sale | $10.95 | 3,661 | 40,088 | 121,075 | Feb 18, 2022, 06:18 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 16, 2022 | Sale | $10.95 | 2,363 | 25,875 | 165,318 | Feb 18, 2022, 06:18 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2022 | Sale | $10.95 | 12,480 | 136,656 | 589,020 | Feb 18, 2022, 06:16 PM |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | Feb 16, 2022 | Sale | $10.95 | 4,852 | 53,129 | 227,802 | Feb 18, 2022, 06:15 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 16, 2022 | Sale | $10.95 | 7,579 | 82,990 | 301,603 | Feb 18, 2022, 06:14 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 18, 2021 | Sale | $12.69 | 3,000 | 38,070 | 256,682 | Nov 18, 2021, 06:06 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 16, 2021 | Sale | $13.16 | 21,149 | 278,321 | 259,682 | Nov 18, 2021, 06:06 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 16, 2021 | Sale | $13.16 | 20,869 | 274,636 | 232,084 | Nov 17, 2021, 06:11 PM |
| Wilson Mark Andrew | SVP & General Counsel | Nov 16, 2021 | Sale | $13.16 | 6,564 | 86,382 | 86,436 | Nov 17, 2021, 06:09 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 16, 2021 | Sale | $13.16 | 6,741 | 88,712 | 145,981 | Nov 17, 2021, 06:08 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2021 | Sale | $13.16 | 42,773 | 562,893 | 475,450 | Nov 17, 2021, 06:07 PM |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | Nov 16, 2021 | Sale | $13.16 | 6,061 | 79,763 | 194,854 | Nov 17, 2021, 06:06 PM |
| GREER R SCOTT | Director | Nov 09, 2021 | Option Exercise | $12.80 | 12,500 | 160,000 | 293,374 | Nov 09, 2021, 05:05 PM |
| Curet Myriam | Director | Sep 22, 2021 | Sale | $17.78 | 3,665 | 65,164 | 25,775 | Sep 24, 2021, 06:14 PM |
| CHESS ROBERT | Director | Sep 22, 2021 | Sale | $17.94 | 4,600 | 82,524 | 279,873 | Sep 24, 2021, 06:13 PM |
| Ajer Jeffrey Robert | Director | Sep 22, 2021 | Sale | $17.78 | 3,665 | 65,164 | 32,510 | Sep 24, 2021, 06:12 PM |
| WHITFIELD ROY A | Director | Sep 16, 2021 | Option Exercise | $13.80 | 40,000 | 552,000 | 225,850 | Sep 17, 2021, 06:44 PM |
| CHESS ROBERT | Director | Sep 08, 2021 | Option Exercise | $13.80 | 8,000 | 110,400 | 282,273 | Sep 10, 2021, 06:03 PM |
| CHESS ROBERT | Director | Sep 09, 2021 | Option Exercise | $13.80 | 10,279 | 141,850 | 284,552 | Sep 10, 2021, 06:03 PM |
| CHESS ROBERT | Director | Sep 09, 2021 | Sale | $16.02 | 10,279 | 164,670 | 274,273 | Sep 10, 2021, 06:03 PM |
| CHESS ROBERT | Director | Sep 08, 2021 | Sale | $16.00 | 8,000 | 128,000 | 274,273 | Sep 10, 2021, 06:03 PM |
| GREER R SCOTT | Director | Aug 31, 2021 | Option Exercise | $12.70 | 45,000 | 571,500 | 270,674 | Aug 31, 2021, 06:26 PM |
| Zalevsky Jonathan | Chief R&D Officer | Aug 16, 2021 | Sale | $13.83 | 7,662 | 105,965 | 212,803 | Aug 18, 2021, 07:04 PM |
| Wilson Mark Andrew | SVP & General Counsel | Aug 16, 2021 | Sale | $13.83 | 1,910 | 26,415 | 72,900 | Aug 18, 2021, 07:02 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2021 | Sale | $13.83 | 11,515 | 159,252 | 424,123 | Aug 18, 2021, 07:01 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2021 | Sale | $13.83 | 13,339 | 184,478 | 137,822 | Aug 18, 2021, 07:00 PM |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | Aug 16, 2021 | Sale | $13.83 | 6,192 | 85,635 | 200,915 | Aug 18, 2021, 06:59 PM |
| Labrucherie Gil M | SVP, COO & CFO | Aug 17, 2021 | Sale | $13.56 | 3,000 | 40,680 | 240,231 | Aug 18, 2021, 06:58 PM |
| Labrucherie Gil M | SVP, COO & CFO | Aug 16, 2021 | Sale | $13.83 | 7,867 | 108,801 | 243,231 | Aug 18, 2021, 06:58 PM |
| CHESS ROBERT | Director | Jul 20, 2021 | Option Exercise | $13.80 | 2,106 | 29,063 | 282,679 | Jul 22, 2021, 07:13 PM |
| CHESS ROBERT | Director | Jul 22, 2021 | Option Exercise | $13.80 | 91 | 1,256 | 280,664 | Jul 22, 2021, 07:13 PM |
| CHESS ROBERT | Director | Jul 21, 2021 | Option Exercise | $13.80 | 3,524 | 48,631 | 284,097 | Jul 22, 2021, 07:13 PM |
| CHESS ROBERT | Director | Jul 20, 2021 | Sale | $16.80 | 2,106 | 35,381 | 280,573 | Jul 22, 2021, 07:13 PM |
| CHESS ROBERT | Director | Jul 22, 2021 | Sale | $16.80 | 91 | 1,529 | 280,573 | Jul 22, 2021, 07:13 PM |
| CHESS ROBERT | Director | Jul 21, 2021 | Sale | $16.81 | 3,524 | 59,238 | 280,573 | Jul 22, 2021, 07:13 PM |
| Labrucherie Gil M | SVP, COO & CFO | May 17, 2021 | Sale | $18.30 | 7,898 | 144,533 | 251,098 | May 19, 2021, 07:04 PM |
| CHESS ROBERT | Director | May 12, 2021 | Option Exercise | $13.80 | 8,000 | 110,400 | 288,573 | May 14, 2021, 06:05 PM |
| CHESS ROBERT | Director | May 12, 2021 | Sale | $19.34 | 8,000 | 154,720 | 280,573 | May 14, 2021, 06:05 PM |
| CHESS ROBERT | Director | Apr 14, 2021 | Option Exercise | $13.80 | 8,000 | 110,400 | 288,573 | Apr 16, 2021, 06:02 PM |
| CHESS ROBERT | Director | Apr 14, 2021 | Sale | $18.98 | 8,000 | 151,840 | 280,573 | Apr 16, 2021, 06:02 PM |
| Zalevsky Jonathan | Chief R&D Officer | Feb 16, 2021 | Sale | $22.37 | 24,141 | 540,034 | 266,176 | Feb 18, 2021, 07:07 PM |
| Wilson Mark Andrew | SVP & General Counsel | Feb 16, 2021 | Sale | $22.37 | 2,173 | 48,610 | 76,727 | Feb 18, 2021, 07:06 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 16, 2021 | Sale | $22.37 | 11,705 | 261,841 | 164,552 | Feb 18, 2021, 07:05 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2021 | Sale | $22.37 | 11,495 | 257,143 | 447,198 | Feb 18, 2021, 07:04 PM |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | Feb 16, 2021 | Sale | $22.37 | 15,358 | 343,558 | 213,192 | Feb 18, 2021, 07:03 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 16, 2021 | Sale | $22.37 | 7,977 | 178,445 | 258,996 | Feb 18, 2021, 07:03 PM |
| Wilson Mark Andrew | SVP & General Counsel | Feb 03, 2021 | Option Exercise | $8.80 | 5,344 | 47,027 | 84,244 | Feb 04, 2021, 08:44 PM |
| Wilson Mark Andrew | SVP & General Counsel | Feb 03, 2021 | Sale | $19.45 | 5,344 | 103,941 | 78,900 | Feb 04, 2021, 08:44 PM |
| ROBIN HOWARD W | President & CEO | Feb 02, 2021 | Option Exercise | $8.80 | 150,000 | 1,320,000 | 608,693 | Feb 04, 2021, 08:43 PM |
| ROBIN HOWARD W | President & CEO | Feb 04, 2021 | Option Exercise | $8.80 | 150,000 | 1,320,000 | 608,693 | Feb 04, 2021, 08:43 PM |
| ROBIN HOWARD W | President & CEO | Feb 03, 2021 | Option Exercise | $8.80 | 150,000 | 1,320,000 | 608,693 | Feb 04, 2021, 08:43 PM |
| ROBIN HOWARD W | President & CEO | Feb 04, 2021 | Sale | $20.29 | 150,000 | 3,042,906 | 516,830 | Feb 04, 2021, 08:43 PM |
| ROBIN HOWARD W | President & CEO | Feb 03, 2021 | Sale | $19.72 | 150,000 | 2,958,000 | 458,693 | Feb 04, 2021, 08:43 PM |
| ROBIN HOWARD W | President & CEO | Feb 02, 2021 | Sale | $19.77 | 150,000 | 2,966,025 | 469,193 | Feb 04, 2021, 08:43 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 04, 2021 | Option Exercise | $8.80 | 50,000 | 440,000 | 316,973 | Feb 04, 2021, 08:42 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 03, 2021 | Option Exercise | $8.80 | 50,000 | 440,000 | 316,973 | Feb 04, 2021, 08:42 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 02, 2021 | Option Exercise | $8.80 | 50,000 | 440,000 | 316,973 | Feb 04, 2021, 08:42 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 04, 2021 | Sale | $19.81 | 50,000 | 990,500 | 266,973 | Feb 04, 2021, 08:42 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 03, 2021 | Sale | $19.61 | 50,000 | 980,500 | 266,973 | Feb 04, 2021, 08:42 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 02, 2021 | Sale | $20.17 | 50,000 | 1,008,629 | 275,838 | Feb 04, 2021, 08:42 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jan 28, 2021 | Option Exercise | $8.80 | 75,000 | 660,000 | 251,257 | Jan 29, 2021, 06:10 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jan 28, 2021 | Sale | $18.62 | 75,000 | 1,396,500 | 176,257 | Jan 29, 2021, 06:10 PM |
| GREER R SCOTT | Director | Jan 05, 2021 | Option Exercise | $13.80 | 40,000 | 552,000 | 225,674 | Jan 05, 2021, 05:09 PM |
| Myriam Curet | Director | Dec 15, 2020 | Sale | $17.82 | 1,560 | 27,799 | 19,240 | Dec 17, 2020, 06:08 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 23, 2020 | Sale | $16.40 | 16,380 | 268,632 | 250,317 | Nov 25, 2020, 06:09 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 16, 2020 | Sale | $16.93 | 29,618 | 501,433 | 266,697 | Nov 18, 2020, 07:08 PM |
| Wilson Mark Andrew | SVP & General Counsel | Nov 16, 2020 | Sale | $16.93 | 1,539 | 26,055 | 49,850 | Nov 18, 2020, 07:07 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 16, 2020 | Sale | $16.93 | 11,976 | 202,754 | 159,757 | Nov 18, 2020, 07:05 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2020 | Sale | $16.93 | 11,975 | 202,737 | 352,043 | Nov 18, 2020, 07:04 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 16, 2020 | Sale | $16.93 | 8,276 | 140,113 | 226,973 | Nov 18, 2020, 07:03 PM |
| Ajer Jeffrey Robert | Director | Sep 28, 2020 | Sale | $17.25 | 3,250 | 56,063 | 25,975 | Sep 30, 2020, 07:03 PM |
| CHESS ROBERT | Director | Sep 25, 2020 | Sale | $17.75 | 5,500 | 97,625 | 280,573 | Sep 25, 2020, 08:16 PM |
| Labrucherie Gil M | SVP, COO & CFO | Sep 17, 2020 | Sale | $19.96 | 2,000 | 39,920 | 235,249 | Sep 21, 2020, 08:59 PM |
| Ajer Jeffrey Robert | Director | Sep 21, 2020 | Sale | $19.74 | 2,250 | 44,415 | 20,125 | Sep 21, 2020, 08:58 PM |
| CHESS ROBERT | Director | Sep 08, 2020 | Option Exercise | $9.24 | 8,000 | 73,920 | 284,973 | Sep 10, 2020, 08:19 PM |
| CHESS ROBERT | Director | Sep 08, 2020 | Sale | $18.53 | 8,000 | 148,240 | 276,973 | Sep 10, 2020, 08:19 PM |
| WHITFIELD ROY A | Director | Sep 04, 2020 | Option Exercise | $9.24 | 30,000 | 277,200 | 228,250 | Sep 08, 2020, 06:18 PM |
| Zalevsky Jonathan | Chief R&D Officer | Aug 17, 2020 | Sale | $19.67 | 26,200 | 515,354 | 296,315 | Aug 19, 2020, 06:41 PM |
| Wilson Mark Andrew | SVP & General Counsel | Aug 17, 2020 | Sale | $19.67 | 1,529 | 30,075 | 51,389 | Aug 19, 2020, 06:40 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 17, 2020 | Sale | $19.67 | 1,367 | 26,889 | 171,733 | Aug 19, 2020, 06:39 PM |
| ROBIN HOWARD W | President & CEO | Aug 17, 2020 | Sale | $19.67 | 11,885 | 233,778 | 364,018 | Aug 19, 2020, 06:38 PM |
| Labrucherie Gil M | SVP, COO & CFO | Aug 18, 2020 | Sale | $19.68 | 2,000 | 39,360 | 237,249 | Aug 19, 2020, 06:37 PM |
| Labrucherie Gil M | SVP, COO & CFO | Aug 17, 2020 | Sale | $19.67 | 6,245 | 122,839 | 239,249 | Aug 19, 2020, 06:37 PM |
| GREER R SCOTT | Director | Jul 09, 2020 | Option Exercise | $9.24 | 40,000 | 369,600 | 191,583 | Jul 10, 2020, 07:06 PM |
| GREER R SCOTT | Director | Jul 09, 2020 | Sale | $25.00 | 15,009 | 375,225 | 176,574 | Jul 10, 2020, 07:06 PM |
| CHESS ROBERT | Director | Jul 08, 2020 | Option Exercise | $9.24 | 8,000 | 73,920 | 284,973 | Jul 10, 2020, 07:05 PM |
| CHESS ROBERT | Director | Jul 08, 2020 | Sale | $24.58 | 8,000 | 196,640 | 276,973 | Jul 10, 2020, 07:05 PM |
| Zalevsky Jonathan | Chief R&D Officer | May 18, 2020 | Sale | $22.51 | 4,558 | 102,601 | 322,515 | May 20, 2020, 06:33 PM |
| Wilson Mark Andrew | SVP & General Counsel | May 18, 2020 | Sale | $22.51 | 1,529 | 34,418 | 52,418 | May 20, 2020, 06:32 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 18, 2020 | Sale | $22.51 | 1,367 | 30,771 | 172,719 | May 20, 2020, 06:31 PM |
| ROBIN HOWARD W | President & CEO | May 18, 2020 | Sale | $22.51 | 8,968 | 201,870 | 375,903 | May 20, 2020, 06:30 PM |
| Labrucherie Gil M | SVP, COO & CFO | May 18, 2020 | Sale | $22.51 | 5,727 | 128,915 | 247,494 | May 20, 2020, 06:29 PM |
| Labrucherie Gil M | SVP, COO & CFO | May 19, 2020 | Sale | $22.62 | 2,000 | 45,240 | 245,494 | May 20, 2020, 06:29 PM |
| CHESS ROBERT | Director | Apr 15, 2020 | Option Exercise | $9.24 | 8,000 | 73,920 | 284,973 | Apr 17, 2020, 06:03 PM |
| CHESS ROBERT | Director | Apr 15, 2020 | Sale | $18.38 | 8,000 | 147,010 | 277,170 | Apr 17, 2020, 06:03 PM |
| CHESS ROBERT | Director | Mar 11, 2020 | Option Exercise | $9.24 | 8,000 | 73,920 | 284,973 | Mar 13, 2020, 06:04 PM |
| CHESS ROBERT | Director | Mar 11, 2020 | Sale | $16.79 | 8,000 | 134,316 | 278,173 | Mar 13, 2020, 06:04 PM |
| Zalevsky Jonathan | Chief R&D Officer | Feb 18, 2020 | Sale | $22.35 | 4,774 | 106,699 | 327,073 | Feb 20, 2020, 06:39 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 18, 2020 | Sale | $22.35 | 1,394 | 31,156 | 174,086 | Feb 20, 2020, 06:39 PM |
| ROBIN HOWARD W | President & CEO | Feb 18, 2020 | Sale | $22.35 | 8,448 | 188,813 | 384,871 | Feb 20, 2020, 06:38 PM |
| Labrucherie Gil M | SVP, COO & CFO | Feb 18, 2020 | Sale | $22.35 | 5,938 | 132,714 | 253,221 | Feb 20, 2020, 06:37 PM |
| CHESS ROBERT | Director | Feb 12, 2020 | Option Exercise | $9.24 | 8,000 | 73,920 | 284,973 | Feb 14, 2020, 07:00 PM |
| CHESS ROBERT | Director | Feb 12, 2020 | Sale | $23.50 | 8,000 | 188,000 | 280,572 | Feb 14, 2020, 07:00 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 06, 2020 | Option Exercise | $7.21 | 37,500 | 270,375 | 212,980 | Feb 07, 2020, 07:31 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 06, 2020 | Sale | $22.78 | 37,500 | 854,250 | 175,480 | Feb 07, 2020, 07:31 PM |
| WHITFIELD ROY A | Director | Dec 18, 2019 | Option Exercise | $9.24 | 10,000 | 92,400 | 198,250 | Dec 20, 2019, 06:31 PM |
| Zalevsky Jonathan | Chief R&D Officer | Nov 18, 2019 | Sale | $17.97 | 3,960 | 71,161 | 291,697 | Nov 20, 2019, 07:07 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 18, 2019 | Sale | $17.97 | 2,713 | 48,753 | 160,441 | Nov 20, 2019, 07:06 PM |
| ROBIN HOWARD W | President & CEO | Nov 18, 2019 | Sale | $17.97 | 13,556 | 243,601 | 299,219 | Nov 20, 2019, 07:05 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 18, 2019 | Sale | $17.97 | 8,863 | 159,268 | 219,009 | Nov 20, 2019, 07:04 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 13, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 252,872 | Nov 15, 2019, 06:09 PM |
| Labrucherie Gil M | SVP, COO & CFO | Nov 13, 2019 | Sale | $19.79 | 25,000 | 494,750 | 227,872 | Nov 15, 2019, 06:09 PM |
| ROBIN HOWARD W | President & CEO | Oct 15, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 346,108 | Oct 17, 2019, 07:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 17, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 346,108 | Oct 17, 2019, 07:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 16, 2019 | Option Exercise | $7.21 | 33,334 | 240,338 | 346,109 | Oct 17, 2019, 07:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 15, 2019 | Sale | $16.95 | 33,333 | 565,085 | 337,275 | Oct 17, 2019, 07:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 17, 2019 | Sale | $17.68 | 33,333 | 589,327 | 312,775 | Oct 17, 2019, 07:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 16, 2019 | Sale | $17.48 | 33,334 | 582,678 | 312,775 | Oct 17, 2019, 07:00 PM |
| Labrucherie Gil M | SVP, COO & CFO | Oct 15, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 252,872 | Oct 17, 2019, 06:59 PM |
| Labrucherie Gil M | SVP, COO & CFO | Oct 15, 2019 | Sale | $15.83 | 25,000 | 395,750 | 227,872 | Oct 17, 2019, 06:59 PM |
| Lingnau Lutz | Director | Sep 27, 2019 | Sale | $17.84 | 3,000 | 53,520 | 26,700 | Oct 02, 2019, 07:51 PM |
| Ajer Jeffrey Robert | Director | Sep 30, 2019 | Sale | $18.06 | 2,375 | 42,892 | 22,375 | Oct 01, 2019, 07:16 PM |
| CHESS ROBERT | Director | Sep 27, 2019 | Sale | $17.99 | 4,000 | 71,960 | 276,973 | Oct 01, 2019, 07:15 PM |
| Ajer Jeffrey Robert | Director | Sep 20, 2019 | Sale | $20.24 | 2,250 | 45,540 | 18,250 | Sep 24, 2019, 06:07 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Sep 16, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 177,872 | Sep 18, 2019, 07:07 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Sep 16, 2019 | Sale | $20.52 | 25,000 | 513,000 | 152,872 | Sep 18, 2019, 07:07 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Sep 05, 2019 | Buy | $17.28 | 15,000 | 259,200 | 107,668 | Sep 09, 2019, 05:09 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 26, 2019 | Option Exercise | $16.31 | 30,000 | 489,300 | 152,872 | Aug 27, 2019, 05:20 PM |
| ROBIN HOWARD W | President & CEO | Aug 23, 2019 | Option Exercise | $16.31 | 30,000 | 489,300 | 312,775 | Aug 26, 2019, 05:21 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2019 | Sale | $18.15 | 1,809 | 32,833 | 163,154 | Aug 19, 2019, 07:09 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2019 | Sale | $18.15 | 12,551 | 227,801 | 282,775 | Aug 19, 2019, 07:08 PM |
| Nicholson John | SVP & Chief Operating Officer | Aug 16, 2019 | Sale | $18.15 | 3,819 | 69,315 | 162,759 | Aug 19, 2019, 07:07 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 16, 2019 | Sale | $18.15 | 5,063 | 91,893 | 122,872 | Aug 19, 2019, 07:07 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Aug 16, 2019 | Sale | $18.15 | 3,245 | 58,897 | 92,668 | Aug 19, 2019, 07:06 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 14, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 152,935 | Aug 16, 2019, 08:13 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 14, 2019 | Sale | $17.79 | 25,000 | 444,750 | 127,935 | Aug 16, 2019, 08:13 PM |
| ROBIN HOWARD W | President & CEO | Jul 25, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 328,659 | Jul 25, 2019, 08:02 PM |
| ROBIN HOWARD W | President & CEO | Jul 24, 2019 | Option Exercise | $7.21 | 33,334 | 240,338 | 328,660 | Jul 25, 2019, 08:02 PM |
| ROBIN HOWARD W | President & CEO | Jul 23, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 328,659 | Jul 25, 2019, 08:02 PM |
| ROBIN HOWARD W | President & CEO | Jul 24, 2019 | Sale | $32.11 | 33,334 | 1,070,355 | 295,326 | Jul 25, 2019, 08:02 PM |
| ROBIN HOWARD W | President & CEO | Jul 23, 2019 | Sale | $32.10 | 33,333 | 1,069,989 | 295,326 | Jul 25, 2019, 08:02 PM |
| ROBIN HOWARD W | President & CEO | Jul 25, 2019 | Sale | $29.65 | 33,333 | 988,323 | 295,326 | Jul 25, 2019, 08:02 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Jul 10, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 152,935 | Jul 12, 2019, 06:31 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Jul 10, 2019 | Sale | $34.57 | 25,000 | 864,250 | 127,935 | Jul 12, 2019, 06:31 PM |
| Lingnau Lutz | Director | Jul 08, 2019 | Option Exercise | $9.24 | 10,000 | 92,400 | 33,200 | Jul 10, 2019, 05:34 PM |
| Lingnau Lutz | Director | Jul 08, 2019 | Sale | $34.63 | 10,000 | 346,300 | 23,200 | Jul 10, 2019, 05:34 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Jun 17, 2019 | Option Exercise | $7.21 | 25,000 | 180,250 | 152,935 | Jun 19, 2019, 05:50 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Jun 17, 2019 | Sale | $33.71 | 25,000 | 842,750 | 127,935 | Jun 19, 2019, 05:50 PM |
| ROBIN HOWARD W | President & CEO | May 22, 2019 | Option Exercise | $7.21 | 33,334 | 240,338 | 328,660 | May 23, 2019, 07:19 PM |
| ROBIN HOWARD W | President & CEO | May 21, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 328,659 | May 23, 2019, 07:19 PM |
| ROBIN HOWARD W | President & CEO | May 23, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 328,659 | May 23, 2019, 07:19 PM |
| ROBIN HOWARD W | President & CEO | May 22, 2019 | Sale | $33.38 | 33,334 | 1,112,689 | 295,326 | May 23, 2019, 07:19 PM |
| ROBIN HOWARD W | President & CEO | May 21, 2019 | Sale | $32.93 | 33,333 | 1,097,656 | 295,326 | May 23, 2019, 07:19 PM |
| ROBIN HOWARD W | President & CEO | May 23, 2019 | Sale | $32.69 | 33,333 | 1,089,656 | 295,326 | May 23, 2019, 07:19 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 16, 2019 | Sale | $31.37 | 1,928 | 60,481 | 164,463 | May 17, 2019, 08:22 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2019 | Sale | $31.37 | 13,383 | 419,825 | 295,326 | May 17, 2019, 08:22 PM |
| Nicholson John | SVP & Chief Operating Officer | May 16, 2019 | Sale | $31.37 | 4,077 | 127,895 | 166,578 | May 17, 2019, 08:21 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 16, 2019 | Sale | $31.37 | 3,767 | 118,171 | 127,935 | May 17, 2019, 08:20 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | May 16, 2019 | Sale | $31.37 | 2,449 | 76,825 | 94,694 | May 17, 2019, 08:19 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | May 16, 2019 | Sale | $31.37 | 3,461 | 108,572 | 95,913 | May 17, 2019, 08:18 PM |
| GREER R SCOTT | Director | Mar 08, 2019 | Option Exercise | $5.14 | 10,000 | 51,400 | 145,083 | Mar 12, 2019, 06:18 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 19, 2019 | Sale | $42.39 | 1,808 | 76,641 | 166,391 | Feb 21, 2019, 08:17 PM |
| ROBIN HOWARD W | President & CEO | Feb 20, 2019 | Option Exercise | $7.21 | 33,334 | 240,338 | 342,043 | Feb 21, 2019, 08:16 PM |
| ROBIN HOWARD W | President & CEO | Feb 19, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 350,924 | Feb 21, 2019, 08:16 PM |
| ROBIN HOWARD W | President & CEO | Feb 21, 2019 | Option Exercise | $7.21 | 33,333 | 240,331 | 342,042 | Feb 21, 2019, 08:16 PM |
| ROBIN HOWARD W | President & CEO | Feb 20, 2019 | Sale | $43.20 | 33,334 | 1,440,029 | 308,709 | Feb 21, 2019, 08:16 PM |
| ROBIN HOWARD W | President & CEO | Feb 19, 2019 | Sale | $42.33 | 42,215 | 1,787,161 | 317,591 | Feb 21, 2019, 08:16 PM |
| ROBIN HOWARD W | President & CEO | Feb 21, 2019 | Sale | $41.01 | 33,333 | 1,366,986 | 308,709 | Feb 21, 2019, 08:16 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 19, 2019 | Sale | $42.39 | 3,822 | 162,015 | 170,655 | Feb 21, 2019, 08:15 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Feb 19, 2019 | Sale | $42.39 | 3,592 | 152,265 | 131,702 | Feb 21, 2019, 08:14 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Feb 19, 2019 | Sale | $42.39 | 2,386 | 101,143 | 97,143 | Feb 21, 2019, 08:13 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Feb 19, 2019 | Sale | $42.39 | 3,310 | 140,311 | 99,374 | Feb 21, 2019, 08:13 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 04, 2019 | Option Exercise | $10.69 | 16,119 | 172,312 | 184,318 | Feb 06, 2019, 07:17 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 04, 2019 | Sale | $42.16 | 16,119 | 679,577 | 168,199 | Feb 06, 2019, 07:17 PM |
| Nicholson John | SVP & Chief Operating Officer | Jan 28, 2019 | Option Exercise | $10.69 | 63,000 | 673,470 | 237,477 | Jan 30, 2019, 06:02 PM |
| Nicholson John | SVP & Chief Operating Officer | Jan 28, 2019 | Sale | $42.82 | 63,000 | 2,697,660 | 174,477 | Jan 30, 2019, 06:02 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 16, 2018 | Sale | $38.25 | 4,016 | 153,612 | 157,249 | Nov 19, 2018, 06:15 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2018 | Sale | $38.25 | 15,326 | 586,220 | 249,141 | Nov 19, 2018, 06:14 PM |
| Nicholson John | SVP & Chief Operating Officer | Nov 16, 2018 | Sale | $38.25 | 5,982 | 228,812 | 174,477 | Nov 19, 2018, 06:14 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Nov 16, 2018 | Sale | $38.25 | 6,515 | 249,199 | 106,544 | Nov 19, 2018, 06:13 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 16, 2018 | Sale | $38.25 | 4,694 | 179,546 | 81,029 | Nov 19, 2018, 06:12 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 16, 2018 | Sale | $38.25 | 4,524 | 173,043 | 78,734 | Nov 19, 2018, 06:11 PM |
| Lingnau Lutz | Director | Sep 20, 2018 | Sale | $56.98 | 9,000 | 512,820 | 18,450 | Sep 21, 2018, 07:32 PM |
| CHESS ROBERT | Director | Sep 19, 2018 | Sale | $56.81 | 4,500 | 255,645 | 269,723 | Sep 21, 2018, 07:31 PM |
| Ajer Jeffrey Robert | Director | Sep 20, 2018 | Sale | $56.76 | 6,750 | 383,130 | 15,750 | Sep 21, 2018, 07:29 PM |
| GREER R SCOTT | Director | Sep 04, 2018 | Option Exercise | $5.14 | 10,000 | 51,400 | 140,333 | Sep 06, 2018, 07:12 PM |
| GREER R SCOTT | Director | Sep 04, 2018 | Sale | $67.39 | 10,000 | 673,900 | 130,333 | Sep 06, 2018, 07:12 PM |
| WINGER DENNIS L | Director | Aug 17, 2018 | Option Exercise | $14.26 | 15,000 | 213,900 | 57,750 | Aug 21, 2018, 07:32 PM |
| WINGER DENNIS L | Director | Aug 21, 2018 | Option Exercise | $14.26 | 15,000 | 213,900 | 57,750 | Aug 21, 2018, 07:32 PM |
| WINGER DENNIS L | Director | Aug 17, 2018 | Sale | $59.62 | 15,000 | 894,300 | 42,750 | Aug 21, 2018, 07:32 PM |
| WINGER DENNIS L | Director | Aug 21, 2018 | Sale | $60.30 | 15,000 | 904,500 | 42,750 | Aug 21, 2018, 07:32 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2018 | Option Exercise | $58.40 | 4,883 | 285,167 | 71,265 | Aug 16, 2018, 09:47 PM |
| Nicholson John | SVP & Chief Operating Officer | Aug 16, 2018 | Option Exercise | $58.40 | 8,137 | 475,201 | 180,459 | Aug 16, 2018, 09:46 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 16, 2018 | Option Exercise | $58.40 | 8,207 | 479,289 | 113,059 | Aug 16, 2018, 09:45 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Aug 16, 2018 | Option Exercise | $58.40 | 5,946 | 347,246 | 85,723 | Aug 16, 2018, 09:44 PM |
| ROBIN HOWARD W | President & CEO | Aug 14, 2018 | Option Exercise | $10.69 | 40,000 | 427,600 | 264,356 | Aug 16, 2018, 09:44 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2018 | Option Exercise | $58.40 | 20,389 | 1,190,718 | 264,467 | Aug 16, 2018, 09:44 PM |
| ROBIN HOWARD W | President & CEO | Aug 14, 2018 | Option Exercise | $60.08 | 40,000 | 2,403,200 | 224,356 | Aug 16, 2018, 09:44 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Aug 16, 2018 | Option Exercise | $58.40 | 6,701 | 391,338 | 83,258 | Aug 16, 2018, 09:43 PM |
| WINGER DENNIS L | Director | Aug 14, 2018 | Sale | $60.15 | 17,125 | 1,030,069 | 42,750 | Aug 15, 2018, 07:30 PM |
| WINGER DENNIS L | Director | Aug 13, 2018 | Sale | $61.04 | 17,125 | 1,045,310 | 59,875 | Aug 15, 2018, 07:30 PM |
| ROBIN HOWARD W | President & CEO | Jun 27, 2018 | Option Exercise | $10.69 | 43,333 | 463,230 | 267,689 | Jun 27, 2018, 07:42 PM |
| ROBIN HOWARD W | President & CEO | Jun 26, 2018 | Option Exercise | $10.69 | 43,333 | 463,230 | 267,689 | Jun 27, 2018, 07:42 PM |
| ROBIN HOWARD W | President & CEO | Jun 25, 2018 | Option Exercise | $10.69 | 43,334 | 463,240 | 267,690 | Jun 27, 2018, 07:42 PM |
| ROBIN HOWARD W | President & CEO | Jun 26, 2018 | Sale | $49.36 | 43,333 | 2,138,917 | 224,356 | Jun 27, 2018, 07:42 PM |
| ROBIN HOWARD W | President & CEO | Jun 25, 2018 | Sale | $51.82 | 43,334 | 2,245,568 | 224,356 | Jun 27, 2018, 07:42 PM |
| ROBIN HOWARD W | President & CEO | Jun 27, 2018 | Sale | $47.39 | 43,333 | 2,053,551 | 224,356 | Jun 27, 2018, 07:42 PM |
| WHITFIELD ROY A | Director | Jun 06, 2018 | Buy | $59.37 | 3,400 | 201,860 | 177,000 | Jun 07, 2018, 07:40 PM |
| WHITFIELD ROY A | Director | Jun 05, 2018 | Buy | $55.22 | 1,600 | 88,352 | 173,600 | Jun 07, 2018, 07:40 PM |
| CHESS ROBERT | Director | Jun 05, 2018 | Option Exercise | $14.26 | 10,000 | 142,600 | 284,223 | Jun 07, 2018, 07:39 PM |
| CHESS ROBERT | Director | Jun 05, 2018 | Sale | $55.16 | 10,000 | 551,600 | 274,223 | Jun 07, 2018, 07:39 PM |
| GREER R SCOTT | Director | Jun 06, 2018 | Option Exercise | $5.14 | 8,600 | 44,204 | 138,933 | Jun 06, 2018, 07:42 PM |
| GREER R SCOTT | Director | Jun 04, 2018 | Option Exercise | $5.14 | 1,400 | 7,196 | 131,733 | Jun 06, 2018, 07:42 PM |
| GREER R SCOTT | Director | Jun 06, 2018 | Sale | $60.00 | 8,600 | 516,000 | 130,333 | Jun 06, 2018, 07:42 PM |
| GREER R SCOTT | Director | Jun 04, 2018 | Sale | $61.99 | 1,400 | 86,786 | 130,333 | Jun 06, 2018, 07:42 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 16, 2018 | Sale | $83.39 | 3,576 | 298,203 | 65,281 | May 18, 2018, 07:07 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2018 | Sale | $83.39 | 12,791 | 1,066,641 | 224,356 | May 18, 2018, 07:06 PM |
| Nicholson John | SVP & Chief Operating Officer | May 16, 2018 | Sale | $83.39 | 4,917 | 410,029 | 162,596 | May 18, 2018, 07:05 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 16, 2018 | Sale | $83.39 | 4,941 | 412,030 | 94,798 | May 18, 2018, 07:03 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | May 16, 2018 | Sale | $83.39 | 4,060 | 338,563 | 76,201 | May 18, 2018, 07:02 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | May 16, 2018 | Sale | $83.39 | 3,435 | 286,445 | 63,959 | May 18, 2018, 07:01 PM |
| CHESS ROBERT | Director | May 03, 2018 | Option Exercise | $8.79 | 25,000 | 219,700 | 289,223 | May 04, 2018, 06:55 PM |
| CHESS ROBERT | Director | May 03, 2018 | Sale | $82.80 | 25,000 | 2,070,050 | 274,223 | May 04, 2018, 06:55 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 01, 2018 | Option Exercise | $10.69 | 30,000 | 320,700 | 129,739 | May 03, 2018, 08:43 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 03, 2018 | Option Exercise | $10.69 | 30,000 | 320,700 | 129,739 | May 03, 2018, 08:43 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 02, 2018 | Option Exercise | $10.69 | 30,000 | 320,700 | 129,739 | May 03, 2018, 08:43 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 03, 2018 | Sale | $82.86 | 30,000 | 2,485,800 | 99,739 | May 03, 2018, 08:43 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 02, 2018 | Sale | $85.63 | 30,000 | 2,568,900 | 99,739 | May 03, 2018, 08:43 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 01, 2018 | Sale | $83.65 | 30,000 | 2,509,500 | 99,739 | May 03, 2018, 08:43 PM |
| ROBIN HOWARD W | President & CEO | May 03, 2018 | Option Exercise | $10.69 | 43,333 | 463,230 | 280,480 | May 03, 2018, 08:42 PM |
| ROBIN HOWARD W | President & CEO | May 02, 2018 | Option Exercise | $10.69 | 43,333 | 463,230 | 280,480 | May 03, 2018, 08:42 PM |
| ROBIN HOWARD W | President & CEO | May 01, 2018 | Option Exercise | $10.69 | 43,334 | 463,240 | 280,481 | May 03, 2018, 08:42 PM |
| ROBIN HOWARD W | President & CEO | May 03, 2018 | Sale | $82.86 | 43,333 | 3,590,572 | 237,147 | May 03, 2018, 08:42 PM |
| ROBIN HOWARD W | President & CEO | May 02, 2018 | Sale | $85.63 | 43,333 | 3,710,605 | 237,147 | May 03, 2018, 08:42 PM |
| ROBIN HOWARD W | President & CEO | May 01, 2018 | Sale | $83.65 | 43,334 | 3,624,889 | 237,147 | May 03, 2018, 08:42 PM |
| WHITFIELD ROY A | Director | Apr 17, 2018 | Option Exercise | $14.26 | 30,000 | 427,800 | 172,000 | Apr 18, 2018, 06:05 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Apr 16, 2018 | Option Exercise | $10.69 | 13,881 | 148,388 | 82,738 | Apr 18, 2018, 06:03 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Apr 16, 2018 | Sale | $101.46 | 13,881 | 1,408,366 | 68,857 | Apr 18, 2018, 06:03 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 10, 2018 | Option Exercise | $7.21 | 502 | 3,619 | 80,763 | Apr 12, 2018, 06:05 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 10, 2018 | Sale | $105.67 | 502 | 53,046 | 80,261 | Apr 12, 2018, 06:05 PM |
| Lingnau Lutz | Director | Apr 05, 2018 | Option Exercise | $9.24 | 30,000 | 277,200 | 57,450 | Apr 09, 2018, 08:23 PM |
| Lingnau Lutz | Director | Apr 05, 2018 | Sale | $101.74 | 30,000 | 3,052,200 | 27,450 | Apr 09, 2018, 08:23 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 09, 2018 | Option Exercise | $7.21 | 9,498 | 68,481 | 89,759 | Apr 09, 2018, 08:22 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 05, 2018 | Option Exercise | $7.21 | 20,000 | 144,200 | 100,261 | Apr 09, 2018, 08:22 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 09, 2018 | Sale | $105.05 | 9,498 | 997,765 | 80,261 | Apr 09, 2018, 08:22 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 05, 2018 | Sale | $101.75 | 20,000 | 2,035,000 | 80,261 | Apr 09, 2018, 08:22 PM |
| GREER R SCOTT | Director | Apr 06, 2018 | Option Exercise | $14.26 | 30,000 | 427,800 | 160,333 | Apr 09, 2018, 08:22 PM |
| GREER R SCOTT | Director | Apr 06, 2018 | Sale | $92.22 | 30,000 | 2,766,600 | 130,333 | Apr 09, 2018, 08:22 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 09, 2018 | Option Exercise | $7.21 | 49,500 | 356,895 | 116,894 | Apr 09, 2018, 08:21 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 06, 2018 | Option Exercise | $9.10 | 110,500 | 1,005,505 | 177,894 | Apr 09, 2018, 08:21 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 09, 2018 | Sale | $96.13 | 49,500 | 4,758,435 | 67,394 | Apr 09, 2018, 08:21 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 06, 2018 | Sale | $91.69 | 110,500 | 10,131,745 | 67,394 | Apr 09, 2018, 08:21 PM |
| CHESS ROBERT | Director | Apr 06, 2018 | Option Exercise | $8.79 | 25,000 | 219,700 | 289,223 | Apr 09, 2018, 08:20 PM |
| CHESS ROBERT | Director | Apr 06, 2018 | Sale | $92.14 | 25,000 | 2,303,600 | 274,223 | Apr 09, 2018, 08:20 PM |
| KUEBLER CHRISTOPHER A | Director | Mar 07, 2018 | Option Exercise | $6.24 | 37,400 | 233,236 | 77,900 | Mar 08, 2018, 06:10 PM |
| KUEBLER CHRISTOPHER A | Director | Mar 06, 2018 | Option Exercise | $5.14 | 2,600 | 13,364 | 43,100 | Mar 08, 2018, 06:10 PM |
| KUEBLER CHRISTOPHER A | Director | Mar 07, 2018 | Sale | $97.41 | 37,400 | 3,643,134 | 40,500 | Mar 08, 2018, 06:10 PM |
| KUEBLER CHRISTOPHER A | Director | Mar 06, 2018 | Sale | $100.30 | 2,600 | 260,780 | 40,500 | Mar 08, 2018, 06:10 PM |
| Nicholson John | SVP & Chief Operating Officer | Mar 07, 2018 | Sale | $100.45 | 100,144 | 10,059,464 | 167,513 | Mar 08, 2018, 06:09 PM |
| Nicholson John | SVP & Chief Operating Officer | Mar 06, 2018 | Sale | $98.29 | 120,000 | 11,794,800 | 267,657 | Mar 08, 2018, 06:09 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 16, 2018 | Sale | $82.94 | 2,545 | 211,082 | 68,857 | Feb 20, 2018, 07:10 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2018 | Sale | $82.94 | 12,788 | 1,060,637 | 237,147 | Feb 20, 2018, 07:10 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 16, 2018 | Sale | $82.94 | 4,879 | 404,664 | 387,657 | Feb 20, 2018, 07:09 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Feb 16, 2018 | Sale | $82.94 | 3,477 | 288,382 | 99,739 | Feb 20, 2018, 07:08 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Feb 16, 2018 | Sale | $82.94 | 2,875 | 238,453 | 80,261 | Feb 20, 2018, 07:07 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Feb 16, 2018 | Sale | $82.94 | 2,426 | 201,212 | 67,394 | Feb 20, 2018, 07:07 PM |
| Nicholson John | SVP & Chief Operating Officer | Jan 31, 2018 | Option Exercise | $11.34 | 120,000 | 1,360,800 | 392,536 | Feb 02, 2018, 06:03 PM |
| ROBIN HOWARD W | President & CEO | Jan 22, 2018 | Option Exercise | $11.34 | 83,333 | 944,996 | 333,268 | Jan 24, 2018, 06:01 PM |
| ROBIN HOWARD W | President & CEO | Jan 22, 2018 | Sale | $75.82 | 83,333 | 6,318,308 | 249,935 | Jan 24, 2018, 06:01 PM |
| WINGER DENNIS L | Director | Jan 04, 2018 | Option Exercise | $11.97 | 33,750 | 403,988 | 77,000 | Jan 08, 2018, 06:07 PM |
| KUEBLER CHRISTOPHER A | Director | Jan 02, 2018 | Option Exercise | $14.26 | 30,000 | 427,800 | 70,500 | Jan 04, 2018, 06:01 PM |
| KUEBLER CHRISTOPHER A | Director | Jan 02, 2018 | Sale | $58.66 | 30,000 | 1,759,800 | 40,500 | Jan 04, 2018, 06:01 PM |
| ROBIN HOWARD W | President & CEO | Dec 13, 2017 | Option Exercise | $11.34 | 83,333 | 944,996 | 272,768 | Dec 15, 2017, 06:00 PM |
| ROBIN HOWARD W | President & CEO | Dec 13, 2017 | Sale | $55.69 | 83,333 | 4,640,815 | 189,435 | Dec 15, 2017, 06:00 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 16, 2017 | Option Exercise | $44.23 | 5,289 | 233,932 | 60,549 | Nov 17, 2017, 06:06 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2017 | Option Exercise | $44.23 | 18,069 | 799,192 | 189,435 | Nov 17, 2017, 06:06 PM |
| Nicholson John | SVP & Chief Operating Officer | Nov 16, 2017 | Option Exercise | $44.23 | 6,620 | 292,803 | 246,536 | Nov 17, 2017, 06:05 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Nov 16, 2017 | Option Exercise | $44.23 | 6,698 | 296,253 | 76,716 | Nov 17, 2017, 06:05 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 16, 2017 | Option Exercise | $44.23 | 5,597 | 247,555 | 67,636 | Nov 17, 2017, 06:04 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Nov 16, 2017 | Option Exercise | $44.23 | 5,022 | 222,123 | 56,553 | Nov 17, 2017, 06:03 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 16, 2017 | Option Exercise | $44.23 | 4,782 | 211,508 | 43,820 | Nov 17, 2017, 06:03 PM |
| Nicholson John | SVP & Chief Operating Officer | Nov 13, 2017 | Option Exercise | $9.24 | 25,000 | 231,000 | 249,066 | Nov 15, 2017, 06:02 PM |
| Nicholson John | SVP & Chief Operating Officer | Nov 13, 2017 | Sale | $37.78 | 15,910 | 601,080 | 233,156 | Nov 15, 2017, 06:02 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 07, 2017 | Option Exercise | $18.10 | 34,600 | 626,260 | 75,533 | Nov 08, 2017, 06:02 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 06, 2017 | Option Exercise | $10.69 | 5,117 | 54,701 | 63,350 | Nov 08, 2017, 06:02 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 06, 2017 | Sale | $25.07 | 5,117 | 128,283 | 58,233 | Nov 08, 2017, 06:02 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 07, 2017 | Option Exercise | $9.53 | 75,409 | 718,648 | 106,511 | Nov 08, 2017, 06:01 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 06, 2017 | Option Exercise | $9.53 | 20,914 | 199,310 | 52,016 | Nov 08, 2017, 06:01 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 08, 2017 | Option Exercise | $9.53 | 300,000 | 2,859,000 | 331,102 | Nov 08, 2017, 06:01 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 06, 2017 | Sale | $24.98 | 20,914 | 522,432 | 31,102 | Nov 08, 2017, 06:01 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 08, 2017 | Sale | $30.09 | 300,000 | 9,027,000 | 31,102 | Nov 08, 2017, 06:01 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 07, 2017 | Sale | $25.78 | 75,409 | 1,944,044 | 31,102 | Nov 08, 2017, 06:01 PM |
| ROBIN HOWARD W | President & CEO | Nov 01, 2017 | Option Exercise | $11.34 | 83,334 | 945,008 | 235,838 | Nov 03, 2017, 06:07 PM |
| ROBIN HOWARD W | President & CEO | Nov 01, 2017 | Sale | $23.57 | 83,334 | 1,964,182 | 152,504 | Nov 03, 2017, 06:07 PM |
| ROBIN HOWARD W | President & CEO | Oct 09, 2017 | Option Exercise | $11.34 | 83,333 | 944,996 | 235,837 | Oct 10, 2017, 06:08 PM |
| ROBIN HOWARD W | President & CEO | Oct 09, 2017 | Sale | $24.20 | 83,333 | 2,016,659 | 152,504 | Oct 10, 2017, 06:08 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Oct 05, 2017 | Option Exercise | $10.69 | 7,583 | 81,062 | 65,816 | Oct 10, 2017, 06:07 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Oct 05, 2017 | Sale | $25.00 | 7,583 | 189,575 | 58,233 | Oct 10, 2017, 06:07 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Oct 05, 2017 | Option Exercise | $9.53 | 43,677 | 416,242 | 74,779 | Oct 10, 2017, 06:06 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Oct 05, 2017 | Sale | $24.97 | 43,677 | 1,090,615 | 31,102 | Oct 10, 2017, 06:06 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Oct 02, 2017 | Option Exercise | $11.34 | 120,000 | 1,360,800 | 183,414 | Oct 03, 2017, 06:06 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Oct 02, 2017 | Sale | $24.45 | 120,000 | 2,934,000 | 63,414 | Oct 03, 2017, 06:06 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Oct 02, 2017 | Option Exercise | $11.04 | 56,704 | 626,012 | 98,279 | Oct 03, 2017, 06:02 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Sep 29, 2017 | Option Exercise | $11.04 | 43,296 | 477,988 | 84,871 | Oct 03, 2017, 06:02 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Oct 02, 2017 | Sale | $24.21 | 56,704 | 1,372,804 | 41,575 | Oct 03, 2017, 06:02 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Sep 29, 2017 | Sale | $24.04 | 43,296 | 1,040,836 | 41,575 | Oct 03, 2017, 06:02 PM |
| Lingnau Lutz | Director | Sep 22, 2017 | Sale | $21.97 | 5,000 | 109,850 | 27,450 | Sep 25, 2017, 06:04 PM |
| KUEBLER CHRISTOPHER A | Director | Sep 22, 2017 | Sale | $21.86 | 4,000 | 87,440 | 40,500 | Sep 25, 2017, 06:03 PM |
| CHESS ROBERT | Director | Sep 21, 2017 | Sale | $21.72 | 6,400 | 139,008 | 274,223 | Sep 25, 2017, 06:02 PM |
| ROBIN HOWARD W | President & CEO | Sep 06, 2017 | Option Exercise | $11.34 | 83,333 | 944,996 | 235,837 | Sep 08, 2017, 06:08 PM |
| ROBIN HOWARD W | President & CEO | Sep 06, 2017 | Sale | $21.54 | 83,333 | 1,794,993 | 152,504 | Sep 08, 2017, 06:08 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2017 | Sale | $19.32 | 2,648 | 51,159 | 50,838 | Aug 18, 2017, 07:05 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2017 | Option Exercise | $11.34 | 83,334 | 945,008 | 235,838 | Aug 18, 2017, 07:05 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2017 | Sale | $19.26 | 91,714 | 1,766,081 | 152,504 | Aug 18, 2017, 07:05 PM |
| Nicholson John | SVP & Chief Operating Officer | Aug 16, 2017 | Sale | $19.32 | 3,177 | 61,380 | 224,066 | Aug 18, 2017, 07:04 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 16, 2017 | Sale | $19.32 | 3,177 | 61,380 | 63,414 | Aug 18, 2017, 07:04 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Aug 16, 2017 | Sale | $19.32 | 2,956 | 57,110 | 58,233 | Aug 18, 2017, 07:03 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Aug 16, 2017 | Sale | $19.32 | 1,997 | 38,582 | 41,575 | Aug 18, 2017, 07:02 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Aug 16, 2017 | Sale | $19.32 | 1,701 | 32,863 | 31,102 | Aug 18, 2017, 07:01 PM |
| WHITFIELD ROY A | Director | Aug 10, 2017 | Buy | $17.95 | 35,000 | 628,250 | 133,000 | Aug 14, 2017, 09:07 AM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 18, 2017 | Option Exercise | $11.04 | 54,920 | 606,317 | 98,492 | Jul 20, 2017, 05:08 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 18, 2017 | Sale | $21.10 | 54,920 | 1,158,812 | 43,572 | Jul 20, 2017, 05:08 PM |
| Lingnau Lutz | Director | Jul 14, 2017 | Option Exercise | $14.26 | 30,000 | 427,800 | 53,450 | Jul 18, 2017, 08:02 PM |
| Lingnau Lutz | Director | Jul 14, 2017 | Sale | $20.76 | 30,000 | 622,800 | 23,450 | Jul 18, 2017, 08:02 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 12, 2017 | Option Exercise | $11.04 | 36,691 | 405,069 | 80,263 | Jul 13, 2017, 08:01 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 11, 2017 | Option Exercise | $11.04 | 8,389 | 92,615 | 51,961 | Jul 13, 2017, 08:01 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 11, 2017 | Sale | $21.04 | 8,389 | 176,505 | 43,572 | Jul 13, 2017, 08:01 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Jul 12, 2017 | Sale | $21.09 | 36,691 | 773,813 | 43,572 | Jul 13, 2017, 08:01 PM |
| Krivulka Joseph J | Director | Jun 26, 2017 | Option Exercise | $8.37 | 15,000 | 125,550 | 73,000 | Jun 28, 2017, 06:05 PM |
| Nicholson John | SVP & Chief Operating Officer | Jun 07, 2017 | Option Exercise | $6.34 | 150,000 | 951,000 | 328,943 | Jun 09, 2017, 06:02 PM |
| Nicholson John | SVP & Chief Operating Officer | Jun 07, 2017 | Sale | $19.24 | 101,700 | 1,956,708 | 227,243 | Jun 09, 2017, 06:02 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 16, 2017 | Sale | $19.55 | 2,651 | 51,827 | 52,986 | May 18, 2017, 08:50 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2017 | Sale | $19.55 | 8,388 | 163,985 | 160,884 | May 18, 2017, 08:50 PM |
| Nicholson John | SVP & Chief Operating Officer | May 16, 2017 | Sale | $19.55 | 3,146 | 61,504 | 178,943 | May 18, 2017, 08:49 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | May 16, 2017 | Sale | $19.55 | 3,179 | 62,149 | 66,091 | May 18, 2017, 08:48 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | May 16, 2017 | Sale | $19.55 | 2,959 | 57,848 | 60,689 | May 18, 2017, 08:47 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | May 16, 2017 | Sale | $19.55 | 1,450 | 28,347 | 43,572 | May 18, 2017, 08:46 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | May 16, 2017 | Sale | $19.55 | 1,701 | 33,255 | 32,803 | May 18, 2017, 08:45 PM |
| CHESS ROBERT | Director | May 15, 2017 | Option Exercise | $8.37 | 5,000 | 41,850 | 276,623 | May 17, 2017, 06:02 PM |
| CHESS ROBERT | Director | May 15, 2017 | Sale | $19.79 | 5,000 | 98,950 | 271,623 | May 17, 2017, 06:02 PM |
| CHESS ROBERT | Director | Apr 17, 2017 | Option Exercise | $8.37 | 5,000 | 41,850 | 276,623 | Apr 19, 2017, 07:30 PM |
| CHESS ROBERT | Director | Apr 17, 2017 | Sale | $18.72 | 5,000 | 93,600 | 271,623 | Apr 19, 2017, 07:30 PM |
| Lingnau Lutz | Director | Apr 07, 2017 | Sale | $20.05 | 7,000 | 140,350 | 23,450 | Apr 11, 2017, 06:04 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 05, 2017 | Option Exercise | $9.53 | 100,000 | 953,000 | 134,504 | Apr 07, 2017, 06:07 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Apr 05, 2017 | Sale | $21.70 | 100,000 | 2,170,000 | 34,504 | Apr 07, 2017, 06:07 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 05, 2017 | Option Exercise | $13.70 | 180,000 | 2,466,000 | 243,648 | Apr 07, 2017, 06:05 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Apr 05, 2017 | Sale | $21.70 | 180,000 | 3,906,000 | 63,648 | Apr 07, 2017, 06:05 PM |
| KUEBLER CHRISTOPHER A | Director | Apr 05, 2017 | Option Exercise | $8.37 | 15,000 | 125,550 | 50,500 | Apr 07, 2017, 06:01 PM |
| KUEBLER CHRISTOPHER A | Director | Apr 05, 2017 | Sale | $21.88 | 15,000 | 328,200 | 35,500 | Apr 07, 2017, 06:01 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Mar 20, 2017 | Option Exercise | $9.96 | 112,500 | 1,120,875 | 168,137 | Mar 22, 2017, 06:04 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Mar 20, 2017 | Sale | $19.69 | 112,500 | 2,215,125 | 55,637 | Mar 22, 2017, 06:04 PM |
| WHITFIELD ROY A | Director | Mar 15, 2017 | Option Exercise | $8.37 | 14,000 | 117,180 | 98,000 | Mar 17, 2017, 06:02 PM |
| CHESS ROBERT | Director | Mar 14, 2017 | Option Exercise | $8.37 | 5,000 | 41,850 | 276,623 | Mar 16, 2017, 06:02 PM |
| CHESS ROBERT | Director | Mar 14, 2017 | Sale | $15.41 | 5,000 | 77,050 | 271,623 | Mar 16, 2017, 06:02 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Mar 02, 2017 | Option Exercise | $6.34 | 167,506 | 1,061,988 | 236,776 | Mar 03, 2017, 07:04 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Mar 03, 2017 | Option Exercise | $8.57 | 32,494 | 278,512 | 94,270 | Mar 03, 2017, 07:04 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Mar 02, 2017 | Sale | $15.15 | 167,506 | 2,537,716 | 69,270 | Mar 03, 2017, 07:04 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Mar 03, 2017 | Sale | $15.21 | 32,494 | 494,234 | 69,270 | Mar 03, 2017, 07:04 PM |
| Lingnau Lutz | Director | Feb 21, 2017 | Option Exercise | $5.14 | 30,000 | 154,200 | 60,450 | Feb 23, 2017, 06:32 PM |
| Lingnau Lutz | Director | Feb 21, 2017 | Sale | $13.08 | 30,000 | 392,400 | 30,450 | Feb 23, 2017, 06:32 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 16, 2017 | Sale | $13.14 | 1,965 | 25,820 | 55,637 | Feb 17, 2017, 08:06 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2017 | Sale | $13.14 | 8,636 | 113,477 | 169,272 | Feb 17, 2017, 08:06 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 16, 2017 | Sale | $13.14 | 3,237 | 42,534 | 182,089 | Feb 17, 2017, 08:05 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Feb 16, 2017 | Sale | $13.14 | 2,359 | 30,997 | 69,270 | Feb 17, 2017, 08:04 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Feb 16, 2017 | Sale | $13.14 | 2,195 | 28,842 | 63,648 | Feb 17, 2017, 08:04 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Feb 16, 2017 | Sale | $13.14 | 1,457 | 19,145 | 45,022 | Feb 17, 2017, 08:03 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Feb 16, 2017 | Sale | $13.14 | 1,261 | 16,570 | 34,504 | Feb 17, 2017, 08:02 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 10, 2017 | Option Exercise | $4.65 | 45,000 | 209,250 | 185,326 | Feb 10, 2017, 08:11 PM |
| ROBIN HOWARD W | President & CEO | Feb 08, 2017 | Option Exercise | $4.65 | 87,500 | 406,875 | 265,408 | Feb 10, 2017, 08:10 PM |
| ROBIN HOWARD W | President & CEO | Feb 08, 2017 | Sale | $13.04 | 87,500 | 1,141,000 | 177,908 | Feb 10, 2017, 08:10 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 03, 2017 | Option Exercise | $4.65 | 8,505 | 39,548 | 148,831 | Feb 06, 2017, 05:20 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 02, 2017 | Option Exercise | $4.65 | 66,495 | 309,202 | 206,821 | Feb 06, 2017, 05:20 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 03, 2017 | Sale | $12.48 | 8,505 | 106,142 | 140,326 | Feb 06, 2017, 05:20 PM |
| Nicholson John | SVP & Chief Operating Officer | Feb 02, 2017 | Sale | $12.38 | 66,495 | 823,208 | 140,326 | Feb 06, 2017, 05:20 PM |
| ROBIN HOWARD W | President & CEO | Jan 17, 2017 | Option Exercise | $4.65 | 87,500 | 406,875 | 265,408 | Jan 19, 2017, 08:01 PM |
| ROBIN HOWARD W | President & CEO | Jan 17, 2017 | Sale | $12.35 | 87,500 | 1,080,625 | 177,908 | Jan 19, 2017, 08:01 PM |
| ROBIN HOWARD W | President & CEO | Dec 07, 2016 | Option Exercise | $4.65 | 87,500 | 406,875 | 210,408 | Dec 09, 2016, 06:03 PM |
| ROBIN HOWARD W | President & CEO | Dec 07, 2016 | Sale | $12.24 | 87,500 | 1,071,000 | 122,908 | Dec 09, 2016, 06:03 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 16, 2016 | Sale | $13.96 | 1,986 | 27,725 | 42,102 | Nov 18, 2016, 06:12 PM |
| ROBIN HOWARD W | President & CEO | Nov 17, 2016 | Option Exercise | $4.65 | 87,500 | 406,875 | 210,408 | Nov 18, 2016, 06:12 PM |
| ROBIN HOWARD W | President & CEO | Nov 17, 2016 | Sale | $13.87 | 87,500 | 1,213,625 | 122,908 | Nov 18, 2016, 06:12 PM |
| ROBIN HOWARD W | President & CEO | Nov 16, 2016 | Sale | $13.96 | 5,958 | 83,174 | 122,908 | Nov 18, 2016, 06:12 PM |
| Nicholson John | SVP & Chief Operating Officer | Nov 16, 2016 | Sale | $13.96 | 1,654 | 23,090 | 120,326 | Nov 18, 2016, 06:11 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Nov 16, 2016 | Sale | $13.96 | 1,654 | 23,090 | 51,129 | Nov 18, 2016, 06:10 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Nov 16, 2016 | Sale | $13.96 | 1,654 | 23,090 | 50,343 | Nov 18, 2016, 06:09 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Nov 16, 2016 | Sale | $13.96 | 848 | 11,838 | 26,479 | Nov 18, 2016, 06:08 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Nov 16, 2016 | Sale | $13.96 | 670 | 9,353 | 18,265 | Nov 18, 2016, 06:07 PM |
| GREER R SCOTT | Director | Oct 24, 2016 | Buy | $13.50 | 15,000 | 202,500 | 121,333 | Oct 25, 2016, 05:00 PM |
| ROBIN HOWARD W | President & CEO | Oct 04, 2016 | Option Exercise | $4.65 | 87,500 | 406,875 | 216,366 | Oct 06, 2016, 05:07 PM |
| ROBIN HOWARD W | President & CEO | Oct 04, 2016 | Sale | $17.06 | 87,500 | 1,492,750 | 128,866 | Oct 06, 2016, 05:07 PM |
| WHITFIELD ROY A | Director | Sep 23, 2016 | Option Exercise | $5.21 | 46,000 | 239,820 | 84,000 | Sep 27, 2016, 05:09 PM |
| Lingnau Lutz | Director | Sep 15, 2016 | Sale | $19.06 | 9,000 | 171,540 | 7,450 | Sep 19, 2016, 05:16 PM |
| KUEBLER CHRISTOPHER A | Director | Sep 16, 2016 | Sale | $19.13 | 7,500 | 143,475 | 27,500 | Sep 19, 2016, 05:15 PM |
| CHESS ROBERT | Director | Sep 15, 2016 | Sale | $19.21 | 12,000 | 230,520 | 248,623 | Sep 19, 2016, 05:13 PM |
| ROBIN HOWARD W | President & CEO | Sep 01, 2016 | Option Exercise | $4.65 | 87,500 | 406,875 | 216,366 | Sep 02, 2016, 08:03 PM |
| ROBIN HOWARD W | President & CEO | Sep 01, 2016 | Sale | $17.83 | 87,500 | 1,560,125 | 128,886 | Sep 02, 2016, 08:03 PM |
| Nicholson John | SVP & Chief Operating Officer | Aug 16, 2016 | Sale | $17.56 | 3,317 | 58,247 | 121,980 | Aug 17, 2016, 05:45 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Aug 16, 2016 | Sale | $17.56 | 3,971 | 69,731 | 44,088 | Aug 17, 2016, 05:42 PM |
| ROBIN HOWARD W | President & CEO | Aug 16, 2016 | Sale | $17.56 | 11,817 | 207,507 | 128,866 | Aug 17, 2016, 05:41 PM |
| Labrucherie Gil M | SVP & Chief Financial Officer | Aug 16, 2016 | Sale | $17.56 | 3,305 | 58,036 | 52,783 | Aug 17, 2016, 05:39 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Aug 16, 2016 | Sale | $17.56 | 3,305 | 58,036 | 51,997 | Aug 17, 2016, 05:38 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Aug 16, 2016 | Sale | $17.56 | 1,685 | 29,589 | 27,327 | Aug 17, 2016, 05:38 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Aug 16, 2016 | Sale | $17.56 | 1,336 | 23,460 | 18,935 | Aug 17, 2016, 05:37 PM |
| CHESS ROBERT | Director | Aug 01, 2016 | Option Exercise | $5.15 | 5,000 | 25,750 | 265,623 | Aug 03, 2016, 07:01 PM |
| CHESS ROBERT | Director | Aug 01, 2016 | Sale | $17.26 | 5,000 | 86,300 | 260,623 | Aug 03, 2016, 07:01 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jul 11, 2016 | Option Exercise | $4.65 | 100,000 | 465,000 | 106,809 | Jul 13, 2016, 05:08 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jul 11, 2016 | Sale | $15.09 | 100,000 | 1,509,000 | 6,809 | Jul 13, 2016, 05:08 PM |
| CHESS ROBERT | Director | Jul 01, 2016 | Option Exercise | $5.15 | 5,000 | 25,750 | 265,623 | Jul 05, 2016, 05:21 PM |
| CHESS ROBERT | Director | Jul 01, 2016 | Sale | $14.10 | 5,000 | 70,500 | 260,623 | Jul 05, 2016, 05:21 PM |
| CHESS ROBERT | Director | Jun 01, 2016 | Option Exercise | $5.15 | 5,000 | 25,750 | 265,623 | Jun 03, 2016, 05:05 PM |
| CHESS ROBERT | Director | Jun 01, 2016 | Sale | $15.50 | 5,000 | 77,500 | 260,623 | Jun 03, 2016, 05:05 PM |
| Nicholson John | SVP & Chief Financial Officer | May 16, 2016 | Option Exercise | $0.00 | 2,167 | 0 | 78,486 | May 18, 2016, 05:23 PM |
| Nicholson John | SVP & Chief Financial Officer | May 17, 2016 | Sale | $13.58 | 856 | 11,624 | 77,630 | May 18, 2016, 05:23 PM |
| ROBIN HOWARD W | President & CEO | May 16, 2016 | Option Exercise | $0.00 | 5,625 | 1 | 19,103 | May 18, 2016, 05:23 PM |
| ROBIN HOWARD W | President & CEO | May 17, 2016 | Sale | $13.58 | 2,170 | 29,469 | 16,933 | May 18, 2016, 05:23 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | May 16, 2016 | Option Exercise | $0.00 | 875 | 0 | 1,360 | May 18, 2016, 05:15 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | May 17, 2016 | Sale | $13.58 | 339 | 4,604 | 1,021 | May 18, 2016, 05:15 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | May 16, 2016 | Option Exercise | $0.00 | 1,250 | 0 | 1,944 | May 18, 2016, 05:14 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | May 17, 2016 | Sale | $13.58 | 432 | 5,867 | 1,512 | May 18, 2016, 05:14 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | May 16, 2016 | Option Exercise | $0.00 | 2,167 | 0 | 7,970 | May 18, 2016, 05:13 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | May 17, 2016 | Sale | $13.58 | 835 | 11,339 | 7,135 | May 18, 2016, 05:13 PM |
| Labrucherie Gil M | SVP & General Counsel | May 16, 2016 | Option Exercise | $0.00 | 2,167 | 0 | 8,757 | May 18, 2016, 05:12 PM |
| Labrucherie Gil M | SVP & General Counsel | May 17, 2016 | Sale | $13.58 | 836 | 11,353 | 7,921 | May 18, 2016, 05:12 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 16, 2016 | Option Exercise | $0.00 | 1,875 | 0 | 7,033 | May 18, 2016, 05:08 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | May 17, 2016 | Sale | $13.58 | 724 | 9,832 | 6,309 | May 18, 2016, 05:08 PM |
| Lingnau Lutz | Director | Apr 25, 2016 | Option Exercise | $8.37 | 15,000 | 125,550 | 31,450 | Apr 27, 2016, 05:08 PM |
| Lingnau Lutz | Director | Apr 25, 2016 | Sale | $16.27 | 15,000 | 244,050 | 16,450 | Apr 27, 2016, 05:08 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Mar 09, 2016 | Option Exercise | $6.65 | 15,000 | 99,750 | 20,158 | Mar 11, 2016, 05:06 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Mar 09, 2016 | Sale | $11.79 | 15,000 | 176,850 | 5,158 | Mar 11, 2016, 05:06 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Feb 16, 2016 | Option Exercise | $0.00 | 1,250 | 0 | 1,250 | Feb 18, 2016, 07:49 PM |
| Gergel Ivan P. | SVP & Chief Medical Officer | Feb 17, 2016 | Sale | $11.92 | 556 | 6,628 | 694 | Feb 18, 2016, 07:49 PM |
| Nicholson John | SVP & Chief Financial Officer | Feb 16, 2016 | Option Exercise | $0.00 | 2,166 | 0 | 77,282 | Feb 18, 2016, 07:48 PM |
| Nicholson John | SVP & Chief Financial Officer | Feb 17, 2016 | Sale | $11.92 | 963 | 11,479 | 76,319 | Feb 18, 2016, 07:48 PM |
| ROBIN HOWARD W | President & CEO | Feb 16, 2016 | Option Exercise | $0.00 | 5,625 | 1 | 15,625 | Feb 18, 2016, 07:48 PM |
| ROBIN HOWARD W | President & CEO | Feb 17, 2016 | Sale | $11.92 | 2,147 | 25,592 | 13,478 | Feb 18, 2016, 07:48 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Feb 16, 2016 | Option Exercise | $0.00 | 875 | 0 | 875 | Feb 18, 2016, 07:47 PM |
| Doberstein Stephen K | SVP & Chief Scientific Officer | Feb 17, 2016 | Sale | $11.92 | 390 | 4,649 | 485 | Feb 18, 2016, 07:47 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 16, 2016 | Option Exercise | $0.00 | 1,875 | 0 | 5,874 | Feb 18, 2016, 07:46 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 17, 2016 | Sale | $11.92 | 716 | 8,535 | 5,158 | Feb 18, 2016, 07:46 PM |
| Labrucherie Gil M | SVP & General Counsel | Feb 16, 2016 | Option Exercise | $0.00 | 2,166 | 0 | 7,417 | Feb 18, 2016, 07:45 PM |
| Labrucherie Gil M | SVP & General Counsel | Feb 17, 2016 | Sale | $11.92 | 827 | 9,858 | 6,590 | Feb 18, 2016, 07:45 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Feb 16, 2016 | Option Exercise | $0.00 | 2,166 | 0 | 6,766 | Feb 18, 2016, 07:45 PM |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | Feb 17, 2016 | Sale | $11.92 | 963 | 11,479 | 5,803 | Feb 18, 2016, 07:45 PM |
| Labrucherie Gil M | SVP & General Counsel | Feb 10, 2016 | Option Exercise | $6.46 | 11,666 | 75,362 | 16,917 | Feb 12, 2016, 05:20 PM |
| Labrucherie Gil M | SVP & General Counsel | Feb 10, 2016 | Sale | $11.49 | 11,666 | 134,042 | 5,251 | Feb 12, 2016, 05:20 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 10, 2016 | Option Exercise | $6.65 | 15,000 | 99,750 | 18,999 | Feb 12, 2016, 05:19 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Feb 10, 2016 | Sale | $11.49 | 15,000 | 172,350 | 3,999 | Feb 12, 2016, 05:19 PM |
| ROBIN HOWARD W | President & CEO | Feb 10, 2016 | Option Exercise | $6.46 | 66,666 | 430,662 | 76,666 | Feb 12, 2016, 05:18 PM |
| ROBIN HOWARD W | President & CEO | Feb 10, 2016 | Sale | $11.49 | 66,666 | 765,992 | 10,000 | Feb 12, 2016, 05:18 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jan 19, 2016 | Option Exercise | $6.65 | 15,000 | 99,750 | 18,999 | Jan 21, 2016, 06:06 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Jan 19, 2016 | Sale | $14.12 | 15,000 | 211,800 | 3,999 | Jan 21, 2016, 06:06 PM |
| ROBIN HOWARD W | President & CEO | Jan 19, 2016 | Option Exercise | $6.46 | 66,667 | 430,669 | 76,667 | Jan 21, 2016, 06:05 PM |
| ROBIN HOWARD W | President & CEO | Jan 19, 2016 | Sale | $14.12 | 66,667 | 941,338 | 10,000 | Jan 21, 2016, 06:05 PM |
| Lingnau Lutz | Director | Jan 20, 2016 | Option Exercise | $5.15 | 15,000 | 77,250 | 31,450 | Jan 21, 2016, 06:04 PM |
| Lingnau Lutz | Director | Jan 20, 2016 | Sale | $14.51 | 15,000 | 217,650 | 16,450 | Jan 21, 2016, 06:04 PM |
| Labrucherie Gil M | SVP & General Counsel | Jan 19, 2016 | Option Exercise | $6.46 | 11,667 | 75,369 | 16,918 | Jan 21, 2016, 06:02 PM |
| Labrucherie Gil M | SVP & General Counsel | Jan 19, 2016 | Sale | $14.12 | 11,667 | 164,738 | 5,251 | Jan 21, 2016, 06:02 PM |
| Labrucherie Gil M | SVP & General Counsel | Dec 03, 2015 | Option Exercise | $6.85 | 45,001 | 308,040 | 50,252 | Dec 07, 2015, 05:36 PM |
| Labrucherie Gil M | SVP & General Counsel | Dec 03, 2015 | Sale | $15.87 | 45,001 | 714,166 | 5,251 | Dec 07, 2015, 05:36 PM |
| ROBIN HOWARD W | President & CEO | Dec 03, 2015 | Option Exercise | $6.70 | 125,001 | 837,840 | 135,001 | Dec 07, 2015, 05:33 PM |
| ROBIN HOWARD W | President & CEO | Dec 03, 2015 | Sale | $15.87 | 125,001 | 1,983,766 | 10,000 | Dec 07, 2015, 05:33 PM |
| KUEBLER CHRISTOPHER A | Director | Dec 04, 2015 | Option Exercise | $5.15 | 15,000 | 77,250 | 35,000 | Dec 07, 2015, 05:31 PM |
| KUEBLER CHRISTOPHER A | Director | Dec 04, 2015 | Sale | $15.82 | 15,000 | 237,300 | 20,000 | Dec 07, 2015, 05:31 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Dec 03, 2015 | Option Exercise | $6.65 | 15,000 | 99,750 | 18,999 | Dec 07, 2015, 05:29 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Dec 03, 2015 | Sale | $15.87 | 15,000 | 238,050 | 3,999 | Dec 07, 2015, 05:29 PM |
| WANG SUSAN | Director | Nov 20, 2015 | Option Exercise | $8.45 | 49,500 | 418,430 | 60,000 | Nov 20, 2015, 05:27 PM |
| WANG SUSAN | Director | Nov 19, 2015 | Option Exercise | $5.14 | 15,128 | 77,758 | 35,128 | Nov 20, 2015, 05:27 PM |
| WANG SUSAN | Director | Nov 18, 2015 | Option Exercise | $7.52 | 20,372 | 153,162 | 35,000 | Nov 20, 2015, 05:27 PM |
| WANG SUSAN | Director | Nov 20, 2015 | Sale | $15.02 | 49,500 | 743,490 | 20,000 | Nov 20, 2015, 05:27 PM |
| WANG SUSAN | Director | Nov 19, 2015 | Sale | $15.02 | 15,128 | 227,223 | 20,000 | Nov 20, 2015, 05:27 PM |
| WANG SUSAN | Director | Nov 18, 2015 | Sale | $15.00 | 20,372 | 305,580 | 20,000 | Nov 20, 2015, 05:27 PM |
| ROBIN HOWARD W | President & CEO | Nov 11, 2015 | Option Exercise | $6.70 | 125,000 | 837,833 | 135,000 | Nov 13, 2015, 05:41 PM |
| ROBIN HOWARD W | President & CEO | Nov 11, 2015 | Sale | $13.52 | 125,000 | 1,690,000 | 10,000 | Nov 13, 2015, 05:41 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 11, 2015 | Option Exercise | $6.85 | 45,000 | 308,033 | 49,751 | Nov 13, 2015, 05:35 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 11, 2015 | Sale | $13.52 | 45,000 | 608,400 | 4,751 | Nov 13, 2015, 05:35 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 11, 2015 | Option Exercise | $6.65 | 15,000 | 99,750 | 18,499 | Nov 13, 2015, 04:12 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Nov 11, 2015 | Sale | $13.52 | 15,000 | 202,800 | 3,499 | Nov 13, 2015, 04:12 PM |
| Lingnau Lutz | Director | Oct 28, 2015 | Option Exercise | $6.65 | 12,500 | 83,125 | 28,950 | Oct 30, 2015, 04:17 PM |
| Lingnau Lutz | Director | Oct 28, 2015 | Sale | $12.00 | 12,500 | 150,000 | 16,450 | Oct 30, 2015, 04:17 PM |
| GREER R SCOTT | Director | Oct 15, 2015 | Option Exercise | $11.34 | 32,500 | 368,550 | 83,333 | Oct 19, 2015, 05:01 PM |
| ROBIN HOWARD W | President & CEO | Oct 06, 2015 | Option Exercise | $6.70 | 125,000 | 837,833 | 135,000 | Oct 08, 2015, 07:12 PM |
| ROBIN HOWARD W | President & CEO | Oct 06, 2015 | Sale | $10.99 | 125,000 | 1,373,750 | 10,000 | Oct 08, 2015, 07:12 PM |
| Labrucherie Gil M | SVP & General Counsel | Oct 06, 2015 | Option Exercise | $6.85 | 45,000 | 308,033 | 49,751 | Oct 08, 2015, 07:11 PM |
| Labrucherie Gil M | SVP & General Counsel | Oct 06, 2015 | Sale | $10.99 | 45,000 | 494,550 | 4,751 | Oct 08, 2015, 07:11 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Oct 06, 2015 | Option Exercise | $6.65 | 15,000 | 99,750 | 18,499 | Oct 08, 2015, 07:09 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Oct 06, 2015 | Sale | $10.99 | 15,000 | 164,850 | 3,499 | Oct 08, 2015, 07:09 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Sep 23, 2015 | Option Exercise | $6.65 | 10,000 | 66,500 | 13,499 | Sep 25, 2015, 05:25 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Sep 23, 2015 | Sale | $13.04 | 10,000 | 130,400 | 3,499 | Sep 25, 2015, 05:25 PM |
| ROBIN HOWARD W | President & CEO | Sep 23, 2015 | Option Exercise | $6.70 | 124,999 | 837,827 | 134,999 | Sep 25, 2015, 05:24 PM |
| ROBIN HOWARD W | President & CEO | Sep 23, 2015 | Sale | $13.04 | 124,999 | 1,629,987 | 10,000 | Sep 25, 2015, 05:24 PM |
| Labrucherie Gil M | SVP & General Counsel | Sep 23, 2015 | Option Exercise | $6.85 | 44,999 | 308,027 | 49,750 | Sep 25, 2015, 05:22 PM |
| Labrucherie Gil M | SVP & General Counsel | Sep 23, 2015 | Sale | $13.04 | 44,999 | 586,787 | 4,751 | Sep 25, 2015, 05:22 PM |
| WHITFIELD ROY A | Director | Sep 11, 2015 | Option Exercise | $8.81 | 15,000 | 132,150 | 15,000 | Sep 15, 2015, 04:12 PM |
| Labrucherie Gil M | SVP & General Counsel | Aug 13, 2015 | Option Exercise | $6.98 | 33,333 | 232,664 | 38,084 | Aug 17, 2015, 04:04 PM |
| Labrucherie Gil M | SVP & General Counsel | Aug 13, 2015 | Sale | $10.89 | 33,333 | 362,996 | 4,751 | Aug 17, 2015, 04:04 PM |
| ROBIN HOWARD W | President & CEO | Aug 13, 2015 | Option Exercise | $6.98 | 58,333 | 407,164 | 68,333 | Aug 17, 2015, 04:03 PM |
| ROBIN HOWARD W | President & CEO | Aug 13, 2015 | Sale | $10.89 | 58,333 | 635,246 | 10,000 | Aug 17, 2015, 04:03 PM |
| Nicholson John | SVP & Chief Financial Officer | Aug 11, 2015 | Option Exercise | $8.26 | 295,000 | 2,437,100 | 164,908 | Aug 13, 2015, 05:10 PM |
| Nicholson John | SVP & Chief Financial Officer | Aug 12, 2015 | Option Exercise | $6.49 | 90,000 | 584,000 | 141,116 | Aug 13, 2015, 05:10 PM |
| Nicholson John | SVP & Chief Financial Officer | Aug 11, 2015 | Sale | $10.87 | 249,908 | 2,716,089 | 10,000 | Aug 13, 2015, 05:10 PM |
| Nicholson John | SVP & Chief Financial Officer | Aug 12, 2015 | Sale | $10.48 | 69,976 | 733,325 | 75,116 | Aug 13, 2015, 05:10 PM |
| Krivulka Joseph J | Director | Jul 24, 2015 | Option Exercise | $8.81 | 15,000 | 132,150 | 35,000 | Jul 28, 2015, 04:06 PM |
| ROBIN HOWARD W | President & CEO | Jul 14, 2015 | Option Exercise | $6.98 | 58,334 | 407,171 | 68,334 | Jul 16, 2015, 04:16 PM |
| ROBIN HOWARD W | President & CEO | Jul 14, 2015 | Sale | $11.78 | 58,334 | 687,175 | 10,000 | Jul 16, 2015, 04:16 PM |
| Labrucherie Gil M | SVP & General Counsel | Jul 14, 2015 | Option Exercise | $6.98 | 33,334 | 232,671 | 37,585 | Jul 16, 2015, 04:14 PM |
| Labrucherie Gil M | SVP & General Counsel | Jul 14, 2015 | Sale | $11.78 | 33,334 | 392,675 | 4,251 | Jul 16, 2015, 04:14 PM |
| WANG SUSAN | Director | Jun 29, 2015 | Option Exercise | $6.98 | 30,000 | 209,400 | 35,000 | Jul 01, 2015, 04:09 PM |
| WANG SUSAN | Director | Jun 29, 2015 | Sale | $12.70 | 30,000 | 381,000 | 20,000 | Jul 01, 2015, 04:09 PM |
| CHESS ROBERT | Director | Jun 19, 2015 | Option Exercise | $8.81 | 15,000 | 132,150 | 275,623 | Jun 23, 2015, 04:05 PM |
| CHESS ROBERT | Director | Jun 19, 2015 | Sale | $11.81 | 15,000 | 177,150 | 260,623 | Jun 23, 2015, 04:05 PM |
| Lingnau Lutz | Director | Jun 15, 2015 | Option Exercise | $6.65 | 25,000 | 166,250 | 41,450 | Jun 17, 2015, 04:07 PM |
| Lingnau Lutz | Director | Jun 15, 2015 | Sale | $11.15 | 25,000 | 278,750 | 16,450 | Jun 17, 2015, 04:07 PM |
| KUEBLER CHRISTOPHER A | Director | Jan 13, 2015 | Option Exercise | $8.81 | 15,000 | 132,150 | 35,000 | Jan 15, 2015, 05:54 PM |
| KUEBLER CHRISTOPHER A | Director | Jan 13, 2015 | Sale | $16.00 | 15,000 | 240,000 | 20,000 | Jan 15, 2015, 05:54 PM |
| CHESS ROBERT | Director | Dec 29, 2014 | Option Exercise | $15.24 | 29,500 | 449,580 | 290,123 | Dec 31, 2014, 05:37 PM |
| CHESS ROBERT | Director | Dec 29, 2014 | Sale | $15.34 | 29,500 | 452,530 | 260,623 | Dec 31, 2014, 05:37 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Dec 22, 2014 | Option Exercise | $11.38 | 5,000 | 56,900 | 7,999 | Dec 24, 2014, 04:09 PM |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | Dec 22, 2014 | Sale | $15.56 | 5,000 | 77,800 | 2,999 | Dec 24, 2014, 04:09 PM |
| Labrucherie Gil M | SVP & General Counsel | Dec 01, 2014 | Option Exercise | $4.65 | 30,000 | 139,500 | 34,251 | Dec 02, 2014, 07:23 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 28, 2014 | Option Exercise | $4.65 | 90,000 | 418,500 | 94,251 | Dec 02, 2014, 07:23 PM |
| Labrucherie Gil M | SVP & General Counsel | Dec 01, 2014 | Sale | $17.00 | 30,000 | 510,000 | 4,251 | Dec 02, 2014, 07:23 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 28, 2014 | Sale | $17.02 | 90,000 | 1,531,800 | 4,251 | Dec 02, 2014, 07:23 PM |
| ROBIN HOWARD W | President & CEO | Nov 28, 2014 | Option Exercise | $6.98 | 140,944 | 983,789 | 150,944 | Dec 02, 2014, 07:22 PM |
| ROBIN HOWARD W | President & CEO | Dec 01, 2014 | Option Exercise | $6.98 | 209,056 | 1,459,211 | 219,056 | Dec 02, 2014, 07:22 PM |
| ROBIN HOWARD W | President & CEO | Nov 28, 2014 | Sale | $17.02 | 140,944 | 2,398,867 | 10,000 | Dec 02, 2014, 07:22 PM |
| ROBIN HOWARD W | President & CEO | Dec 01, 2014 | Sale | $17.00 | 209,056 | 3,553,952 | 10,000 | Dec 02, 2014, 07:22 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 24, 2014 | Option Exercise | $13.02 | 10,500 | 136,710 | 14,251 | Nov 26, 2014, 05:47 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 24, 2014 | Sale | $15.04 | 10,500 | 157,920 | 3,751 | Nov 26, 2014, 05:47 PM |
| ROBIN HOWARD W | President & CEO | Nov 24, 2014 | Option Exercise | $14.52 | 132,800 | 1,928,256 | 142,800 | Nov 26, 2014, 05:41 PM |
| ROBIN HOWARD W | President & CEO | Nov 25, 2014 | Option Exercise | $14.52 | 467,200 | 6,783,744 | 477,200 | Nov 26, 2014, 05:41 PM |
| ROBIN HOWARD W | President & CEO | Nov 25, 2014 | Sale | $15.31 | 467,200 | 7,152,832 | 10,000 | Nov 26, 2014, 05:41 PM |
| ROBIN HOWARD W | President & CEO | Nov 24, 2014 | Sale | $15.02 | 132,800 | 1,994,656 | 10,000 | Nov 26, 2014, 05:41 PM |
| Lingnau Lutz | Director | Nov 24, 2014 | Option Exercise | $8.81 | 15,000 | 132,150 | 31,450 | Nov 26, 2014, 05:39 PM |
| Lingnau Lutz | Director | Nov 24, 2014 | Sale | $15.02 | 15,000 | 225,300 | 16,450 | Nov 26, 2014, 05:39 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 03, 2014 | Option Exercise | $11.38 | 9,900 | 112,662 | 13,651 | Nov 04, 2014, 01:41 PM |
| Labrucherie Gil M | SVP & General Counsel | Nov 03, 2014 | Sale | $13.78 | 9,900 | 136,422 | 3,751 | Nov 04, 2014, 01:41 PM |
| KUEBLER CHRISTOPHER A | Director | Aug 05, 2013 | Option Exercise | $11.41 | 12,500 | 142,625 | 32,500 | Aug 08, 2013, 05:14 PM |
| KUEBLER CHRISTOPHER A | Director | Aug 05, 2013 | Sale | $12.41 | 12,500 | 155,125 | 20,000 | Aug 08, 2013, 05:14 PM |
| WHITFIELD ROY A | Director | Aug 05, 2013 | Option Exercise | $11.41 | 12,500 | 142,625 | 32,500 | Aug 07, 2013, 04:30 PM |
| WHITFIELD ROY A | Director | Aug 05, 2013 | Sale | $12.41 | 12,500 | 155,125 | 20,000 | Aug 07, 2013, 04:30 PM |
| KUEBLER CHRISTOPHER A | Director | Sep 27, 2012 | Option Exercise | $8.66 | 12,500 | 108,250 | 32,500 | Oct 01, 2012, 04:02 PM |
| KUEBLER CHRISTOPHER A | Director | Sep 27, 2012 | Sale | $10.66 | 12,500 | 133,250 | 20,000 | Oct 01, 2012, 04:02 PM |
| WINGER DENNIS L | Director | Sep 14, 2012 | Buy | $9.18 | 5,000 | 45,908 | 5,000 | Sep 18, 2012, 02:34 PM |
| CHESS ROBERT | Director | Jul 13, 2012 | Option Exercise | $6.12 | 24,001 | 146,886 | 284,624 | Jul 17, 2012, 04:10 PM |
| CHESS ROBERT | Director | Jul 13, 2012 | Sale | $8.50 | 24,001 | 204,009 | 260,623 | Jul 17, 2012, 04:10 PM |
| CHESS ROBERT | Director | Mar 08, 2011 | Sale | $9.00 | 4,500 | 40,500 | 255,709 | Mar 09, 2011, 12:14 PM |
Load More Insider Transactions
Buy
Sale
Option Exercise
| Owner | Relationship | Date | Value($) |
| Zalevsky Jonathan | Chief R&D Officer | 08/19/2024 | 8,788 |
| Wilson Mark Andrew | Chief Legal Officer | 08/19/2024 | 7,233 |
| ROBIN HOWARD W | President & CEO | 08/19/2024 | 19,048 |
| CHESS ROBERT | Director | 06/14/2024 | 23,400 |
| ROBIN HOWARD W | President & CEO | 05/17/2024 | 29,138 |
| Zalevsky Jonathan | Chief R&D Officer | 05/17/2024 | 12,871 |
| Wilson Mark Andrew | Chief Legal Officer | 05/17/2024 | 10,955 |
| Deep Track Capital, LP | 10% Owner | 05/10/2024 | 99,630 |
| Zalevsky Jonathan | Chief R&D Officer | 02/20/2024 | 6,130 |
| Wilson Mark Andrew | Chief Legal Officer | 02/20/2024 | 5,172 |
| ROBIN HOWARD W | President & CEO | 02/20/2024 | 13,622 |
| Zalevsky Jonathan | Chief R&D Officer | 11/17/2023 | 4,727 |
| Wilson Mark Andrew | Chief Legal Officer | 11/17/2023 | 3,518 |
| ROBIN HOWARD W | President & CEO | 11/17/2023 | 9,740 |
| Curet Myriam | Director | 09/18/2023 | 3,008 |
| CHESS ROBERT | Director | 09/22/2022 | 6,834 |
| Ajer Jeffrey Robert | Director | 09/18/2023 | 3,008 |
| Zalevsky Jonathan | Chief R&D Officer | 08/16/2023 | 7,568 |
| Wilson Mark Andrew | Chief Legal Officer | 08/16/2023 | 5,632 |
| ROBIN HOWARD W | President & CEO | 08/16/2023 | 15,598 |
| WHITFIELD ROY A | Director | 06/14/2023 | 17,100 |
| Zalevsky Jonathan | Chief R&D Officer | 05/16/2023 | 7,050 |
| Wilson Mark Andrew | Chief Legal Officer | 05/16/2023 | 5,431 |
| ROBIN HOWARD W | President & CEO | 05/16/2023 | 14,660 |
| Zalevsky Jonathan | Chief R&D Officer | 02/16/2023 | 31,452 |
| Wilson Mark Andrew | Chief Legal Officer | 02/16/2023 | 24,825 |
| Thomsen Jillian B. | Chief Financial Officer | 02/16/2023 | 30,801 |
| ROBIN HOWARD W | President & CEO | 02/16/2023 | 58,905 |
| Zalevsky Jonathan | Chief R&D Officer | 11/16/2022 | 48,052 |
| Wilson Mark Andrew | Chief Legal Officer | 11/16/2022 | 31,023 |
| Thomsen Jillian B. | Chief Financial Officer | 11/16/2022 | 39,609 |
| ROBIN HOWARD W | President & CEO | 11/16/2022 | 135,710 |
| Curet Myriam | Director | 09/23/2022 | 13,266 |
| Ajer Jeffrey Robert | Director | 09/23/2022 | 13,266 |
| CHESS ROBERT | Director | 09/22/2022 | 16,269 |
| EASTHAM KARIN | Director | 09/13/2022 | 76,774 |
| Zalevsky Jonathan | Chief R&D Officer | 08/18/2022 | 342,779 |
| Zalevsky Jonathan | Chief R&D Officer | 08/16/2022 | 50,266 |
| Wilson Mark Andrew | SVP & General Counsel | 08/16/2022 | 15,180 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2022 | 9,549 |
| ROBIN HOWARD W | President & CEO | 08/16/2022 | 65,493 |
| Zalevsky Jonathan | Chief R&D Officer | 05/16/2022 | 85,608 |
| Wilson Mark Andrew | SVP & General Counsel | 05/16/2022 | 12,387 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/16/2022 | 23,072 |
| ROBIN HOWARD W | President & CEO | 05/16/2022 | 144,290 |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | 05/16/2022 | 18,138 |
| Labrucherie Gil M | SVP, COO & CFO | 05/16/2022 | 68,920 |
| Zalevsky Jonathan | Chief R&D Officer | 02/16/2022 | 119,486 |
| Wilson Mark Andrew | SVP & General Counsel | 02/16/2022 | 40,088 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/16/2022 | 25,875 |
| ROBIN HOWARD W | President & CEO | 02/16/2022 | 136,656 |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | 02/16/2022 | 53,129 |
| Labrucherie Gil M | SVP, COO & CFO | 02/16/2022 | 82,990 |
| Labrucherie Gil M | SVP, COO & CFO | 11/18/2021 | 38,070 |
| Labrucherie Gil M | SVP, COO & CFO | 11/16/2021 | 278,321 |
| Zalevsky Jonathan | Chief R&D Officer | 11/16/2021 | 274,636 |
| Wilson Mark Andrew | SVP & General Counsel | 11/16/2021 | 86,382 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/16/2021 | 88,712 |
| ROBIN HOWARD W | President & CEO | 11/16/2021 | 562,893 |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | 11/16/2021 | 79,763 |
| GREER R SCOTT | Director | 11/09/2021 | 160,000 |
| Curet Myriam | Director | 09/22/2021 | 65,164 |
| CHESS ROBERT | Director | 09/22/2021 | 82,524 |
| Ajer Jeffrey Robert | Director | 09/22/2021 | 65,164 |
| WHITFIELD ROY A | Director | 09/16/2021 | 552,000 |
| CHESS ROBERT | Director | 09/08/2021 | 110,400 |
| CHESS ROBERT | Director | 09/09/2021 | 141,850 |
| CHESS ROBERT | Director | 09/09/2021 | 164,670 |
| CHESS ROBERT | Director | 09/08/2021 | 128,000 |
| GREER R SCOTT | Director | 08/31/2021 | 571,500 |
| Zalevsky Jonathan | Chief R&D Officer | 08/16/2021 | 105,965 |
| Wilson Mark Andrew | SVP & General Counsel | 08/16/2021 | 26,415 |
| ROBIN HOWARD W | President & CEO | 08/16/2021 | 159,252 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2021 | 184,478 |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | 08/16/2021 | 85,635 |
| Labrucherie Gil M | SVP, COO & CFO | 08/17/2021 | 40,680 |
| Labrucherie Gil M | SVP, COO & CFO | 08/16/2021 | 108,801 |
| CHESS ROBERT | Director | 07/20/2021 | 29,063 |
| CHESS ROBERT | Director | 07/22/2021 | 1,256 |
| CHESS ROBERT | Director | 07/21/2021 | 48,631 |
| CHESS ROBERT | Director | 07/20/2021 | 35,381 |
| CHESS ROBERT | Director | 07/22/2021 | 1,529 |
| CHESS ROBERT | Director | 07/21/2021 | 59,238 |
| Labrucherie Gil M | SVP, COO & CFO | 05/17/2021 | 144,533 |
| CHESS ROBERT | Director | 05/12/2021 | 110,400 |
| CHESS ROBERT | Director | 05/12/2021 | 154,720 |
| CHESS ROBERT | Director | 04/14/2021 | 110,400 |
| CHESS ROBERT | Director | 04/14/2021 | 151,840 |
| Zalevsky Jonathan | Chief R&D Officer | 02/16/2021 | 540,034 |
| Wilson Mark Andrew | SVP & General Counsel | 02/16/2021 | 48,610 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/16/2021 | 261,841 |
| ROBIN HOWARD W | President & CEO | 02/16/2021 | 257,143 |
| NORTHCOTT JOHN | SVP & Chief Commercial Officer | 02/16/2021 | 343,558 |
| Labrucherie Gil M | SVP, COO & CFO | 02/16/2021 | 178,445 |
| Wilson Mark Andrew | SVP & General Counsel | 02/03/2021 | 47,027 |
| Wilson Mark Andrew | SVP & General Counsel | 02/03/2021 | 103,941 |
| ROBIN HOWARD W | President & CEO | 02/02/2021 | 1,320,000 |
| ROBIN HOWARD W | President & CEO | 02/04/2021 | 1,320,000 |
| ROBIN HOWARD W | President & CEO | 02/03/2021 | 1,320,000 |
| ROBIN HOWARD W | President & CEO | 02/04/2021 | 3,042,906 |
| ROBIN HOWARD W | President & CEO | 02/03/2021 | 2,958,000 |
| ROBIN HOWARD W | President & CEO | 02/02/2021 | 2,966,025 |
| Labrucherie Gil M | SVP, COO & CFO | 02/04/2021 | 440,000 |
| Labrucherie Gil M | SVP, COO & CFO | 02/03/2021 | 440,000 |
| Labrucherie Gil M | SVP, COO & CFO | 02/02/2021 | 440,000 |
| Labrucherie Gil M | SVP, COO & CFO | 02/04/2021 | 990,500 |
| Labrucherie Gil M | SVP, COO & CFO | 02/03/2021 | 980,500 |
| Labrucherie Gil M | SVP, COO & CFO | 02/02/2021 | 1,008,629 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 01/28/2021 | 660,000 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 01/28/2021 | 1,396,500 |
| GREER R SCOTT | Director | 01/05/2021 | 552,000 |
| Myriam Curet | Director | 12/15/2020 | 27,799 |
| Zalevsky Jonathan | Chief R&D Officer | 11/23/2020 | 268,632 |
| Zalevsky Jonathan | Chief R&D Officer | 11/16/2020 | 501,433 |
| Wilson Mark Andrew | SVP & General Counsel | 11/16/2020 | 26,055 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/16/2020 | 202,754 |
| ROBIN HOWARD W | President & CEO | 11/16/2020 | 202,737 |
| Labrucherie Gil M | SVP, COO & CFO | 11/16/2020 | 140,113 |
| Ajer Jeffrey Robert | Director | 09/28/2020 | 56,063 |
| CHESS ROBERT | Director | 09/25/2020 | 97,625 |
| Labrucherie Gil M | SVP, COO & CFO | 09/17/2020 | 39,920 |
| Ajer Jeffrey Robert | Director | 09/21/2020 | 44,415 |
| CHESS ROBERT | Director | 09/08/2020 | 73,920 |
| CHESS ROBERT | Director | 09/08/2020 | 148,240 |
| WHITFIELD ROY A | Director | 09/04/2020 | 277,200 |
| Zalevsky Jonathan | Chief R&D Officer | 08/17/2020 | 515,354 |
| Wilson Mark Andrew | SVP & General Counsel | 08/17/2020 | 30,075 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/17/2020 | 26,889 |
| ROBIN HOWARD W | President & CEO | 08/17/2020 | 233,778 |
| Labrucherie Gil M | SVP, COO & CFO | 08/18/2020 | 39,360 |
| Labrucherie Gil M | SVP, COO & CFO | 08/17/2020 | 122,839 |
| GREER R SCOTT | Director | 07/09/2020 | 369,600 |
| GREER R SCOTT | Director | 07/09/2020 | 375,225 |
| CHESS ROBERT | Director | 07/08/2020 | 73,920 |
| CHESS ROBERT | Director | 07/08/2020 | 196,640 |
| Zalevsky Jonathan | Chief R&D Officer | 05/18/2020 | 102,601 |
| Wilson Mark Andrew | SVP & General Counsel | 05/18/2020 | 34,418 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/18/2020 | 30,771 |
| ROBIN HOWARD W | President & CEO | 05/18/2020 | 201,870 |
| Labrucherie Gil M | SVP, COO & CFO | 05/18/2020 | 128,915 |
| Labrucherie Gil M | SVP, COO & CFO | 05/19/2020 | 45,240 |
| CHESS ROBERT | Director | 04/15/2020 | 73,920 |
| CHESS ROBERT | Director | 04/15/2020 | 147,010 |
| CHESS ROBERT | Director | 03/11/2020 | 73,920 |
| CHESS ROBERT | Director | 03/11/2020 | 134,316 |
| Zalevsky Jonathan | Chief R&D Officer | 02/18/2020 | 106,699 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/18/2020 | 31,156 |
| ROBIN HOWARD W | President & CEO | 02/18/2020 | 188,813 |
| Labrucherie Gil M | SVP, COO & CFO | 02/18/2020 | 132,714 |
| CHESS ROBERT | Director | 02/12/2020 | 73,920 |
| CHESS ROBERT | Director | 02/12/2020 | 188,000 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/06/2020 | 270,375 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/06/2020 | 854,250 |
| WHITFIELD ROY A | Director | 12/18/2019 | 92,400 |
| Zalevsky Jonathan | Chief R&D Officer | 11/18/2019 | 71,161 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/18/2019 | 48,753 |
| ROBIN HOWARD W | President & CEO | 11/18/2019 | 243,601 |
| Labrucherie Gil M | SVP, COO & CFO | 11/18/2019 | 159,268 |
| Labrucherie Gil M | SVP, COO & CFO | 11/13/2019 | 180,250 |
| Labrucherie Gil M | SVP, COO & CFO | 11/13/2019 | 494,750 |
| ROBIN HOWARD W | President & CEO | 10/15/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 10/17/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 10/16/2019 | 240,338 |
| ROBIN HOWARD W | President & CEO | 10/15/2019 | 565,085 |
| ROBIN HOWARD W | President & CEO | 10/17/2019 | 589,327 |
| ROBIN HOWARD W | President & CEO | 10/16/2019 | 582,678 |
| Labrucherie Gil M | SVP, COO & CFO | 10/15/2019 | 180,250 |
| Labrucherie Gil M | SVP, COO & CFO | 10/15/2019 | 395,750 |
| Lingnau Lutz | Director | 09/27/2019 | 53,520 |
| Ajer Jeffrey Robert | Director | 09/30/2019 | 42,892 |
| CHESS ROBERT | Director | 09/27/2019 | 71,960 |
| Ajer Jeffrey Robert | Director | 09/20/2019 | 45,540 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 09/16/2019 | 180,250 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 09/16/2019 | 513,000 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 09/05/2019 | 259,200 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/26/2019 | 489,300 |
| ROBIN HOWARD W | President & CEO | 08/23/2019 | 489,300 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2019 | 32,833 |
| ROBIN HOWARD W | President & CEO | 08/16/2019 | 227,801 |
| Nicholson John | SVP & Chief Operating Officer | 08/16/2019 | 69,315 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/16/2019 | 91,893 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 08/16/2019 | 58,897 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/14/2019 | 180,250 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/14/2019 | 444,750 |
| ROBIN HOWARD W | President & CEO | 07/25/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 07/24/2019 | 240,338 |
| ROBIN HOWARD W | President & CEO | 07/23/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 07/24/2019 | 1,070,355 |
| ROBIN HOWARD W | President & CEO | 07/23/2019 | 1,069,989 |
| ROBIN HOWARD W | President & CEO | 07/25/2019 | 988,323 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 07/10/2019 | 180,250 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 07/10/2019 | 864,250 |
| Lingnau Lutz | Director | 07/08/2019 | 92,400 |
| Lingnau Lutz | Director | 07/08/2019 | 346,300 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 06/17/2019 | 180,250 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 06/17/2019 | 842,750 |
| ROBIN HOWARD W | President & CEO | 05/22/2019 | 240,338 |
| ROBIN HOWARD W | President & CEO | 05/21/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 05/23/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 05/22/2019 | 1,112,689 |
| ROBIN HOWARD W | President & CEO | 05/21/2019 | 1,097,656 |
| ROBIN HOWARD W | President & CEO | 05/23/2019 | 1,089,656 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/16/2019 | 60,481 |
| ROBIN HOWARD W | President & CEO | 05/16/2019 | 419,825 |
| Nicholson John | SVP & Chief Operating Officer | 05/16/2019 | 127,895 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/16/2019 | 118,171 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 05/16/2019 | 76,825 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 05/16/2019 | 108,572 |
| GREER R SCOTT | Director | 03/08/2019 | 51,400 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/19/2019 | 76,641 |
| ROBIN HOWARD W | President & CEO | 02/20/2019 | 240,338 |
| ROBIN HOWARD W | President & CEO | 02/19/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 02/21/2019 | 240,331 |
| ROBIN HOWARD W | President & CEO | 02/20/2019 | 1,440,029 |
| ROBIN HOWARD W | President & CEO | 02/19/2019 | 1,787,161 |
| ROBIN HOWARD W | President & CEO | 02/21/2019 | 1,366,986 |
| Nicholson John | SVP & Chief Operating Officer | 02/19/2019 | 162,015 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 02/19/2019 | 152,265 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 02/19/2019 | 101,143 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 02/19/2019 | 140,311 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/04/2019 | 172,312 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/04/2019 | 679,577 |
| Nicholson John | SVP & Chief Operating Officer | 01/28/2019 | 673,470 |
| Nicholson John | SVP & Chief Operating Officer | 01/28/2019 | 2,697,660 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/16/2018 | 153,612 |
| ROBIN HOWARD W | President & CEO | 11/16/2018 | 586,220 |
| Nicholson John | SVP & Chief Operating Officer | 11/16/2018 | 228,812 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 11/16/2018 | 249,199 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/16/2018 | 179,546 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/16/2018 | 173,043 |
| Lingnau Lutz | Director | 09/20/2018 | 512,820 |
| CHESS ROBERT | Director | 09/19/2018 | 255,645 |
| Ajer Jeffrey Robert | Director | 09/20/2018 | 383,130 |
| GREER R SCOTT | Director | 09/04/2018 | 51,400 |
| GREER R SCOTT | Director | 09/04/2018 | 673,900 |
| WINGER DENNIS L | Director | 08/17/2018 | 213,900 |
| WINGER DENNIS L | Director | 08/21/2018 | 213,900 |
| WINGER DENNIS L | Director | 08/17/2018 | 894,300 |
| WINGER DENNIS L | Director | 08/21/2018 | 904,500 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2018 | 285,167 |
| Nicholson John | SVP & Chief Operating Officer | 08/16/2018 | 475,201 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/16/2018 | 479,289 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 08/16/2018 | 347,246 |
| ROBIN HOWARD W | President & CEO | 08/14/2018 | 427,600 |
| ROBIN HOWARD W | President & CEO | 08/16/2018 | 1,190,718 |
| ROBIN HOWARD W | President & CEO | 08/14/2018 | 2,403,200 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 08/16/2018 | 391,338 |
| WINGER DENNIS L | Director | 08/14/2018 | 1,030,069 |
| WINGER DENNIS L | Director | 08/13/2018 | 1,045,310 |
| ROBIN HOWARD W | President & CEO | 06/27/2018 | 463,230 |
| ROBIN HOWARD W | President & CEO | 06/26/2018 | 463,230 |
| ROBIN HOWARD W | President & CEO | 06/25/2018 | 463,240 |
| ROBIN HOWARD W | President & CEO | 06/26/2018 | 2,138,917 |
| ROBIN HOWARD W | President & CEO | 06/25/2018 | 2,245,568 |
| ROBIN HOWARD W | President & CEO | 06/27/2018 | 2,053,551 |
| WHITFIELD ROY A | Director | 06/06/2018 | 201,860 |
| WHITFIELD ROY A | Director | 06/05/2018 | 88,352 |
| CHESS ROBERT | Director | 06/05/2018 | 142,600 |
| CHESS ROBERT | Director | 06/05/2018 | 551,600 |
| GREER R SCOTT | Director | 06/06/2018 | 44,204 |
| GREER R SCOTT | Director | 06/04/2018 | 7,196 |
| GREER R SCOTT | Director | 06/06/2018 | 516,000 |
| GREER R SCOTT | Director | 06/04/2018 | 86,786 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/16/2018 | 298,203 |
| ROBIN HOWARD W | President & CEO | 05/16/2018 | 1,066,641 |
| Nicholson John | SVP & Chief Operating Officer | 05/16/2018 | 410,029 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/16/2018 | 412,030 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 05/16/2018 | 338,563 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 05/16/2018 | 286,445 |
| CHESS ROBERT | Director | 05/03/2018 | 219,700 |
| CHESS ROBERT | Director | 05/03/2018 | 2,070,050 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/01/2018 | 320,700 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/03/2018 | 320,700 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/02/2018 | 320,700 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/03/2018 | 2,485,800 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/02/2018 | 2,568,900 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/01/2018 | 2,509,500 |
| ROBIN HOWARD W | President & CEO | 05/03/2018 | 463,230 |
| ROBIN HOWARD W | President & CEO | 05/02/2018 | 463,230 |
| ROBIN HOWARD W | President & CEO | 05/01/2018 | 463,240 |
| ROBIN HOWARD W | President & CEO | 05/03/2018 | 3,590,572 |
| ROBIN HOWARD W | President & CEO | 05/02/2018 | 3,710,605 |
| ROBIN HOWARD W | President & CEO | 05/01/2018 | 3,624,889 |
| WHITFIELD ROY A | Director | 04/17/2018 | 427,800 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 04/16/2018 | 148,388 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 04/16/2018 | 1,408,366 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/10/2018 | 3,619 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/10/2018 | 53,046 |
| Lingnau Lutz | Director | 04/05/2018 | 277,200 |
| Lingnau Lutz | Director | 04/05/2018 | 3,052,200 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/09/2018 | 68,481 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/05/2018 | 144,200 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/09/2018 | 997,765 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/05/2018 | 2,035,000 |
| GREER R SCOTT | Director | 04/06/2018 | 427,800 |
| GREER R SCOTT | Director | 04/06/2018 | 2,766,600 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/09/2018 | 356,895 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/06/2018 | 1,005,505 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/09/2018 | 4,758,435 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/06/2018 | 10,131,745 |
| CHESS ROBERT | Director | 04/06/2018 | 219,700 |
| CHESS ROBERT | Director | 04/06/2018 | 2,303,600 |
| KUEBLER CHRISTOPHER A | Director | 03/07/2018 | 233,236 |
| KUEBLER CHRISTOPHER A | Director | 03/06/2018 | 13,364 |
| KUEBLER CHRISTOPHER A | Director | 03/07/2018 | 3,643,134 |
| KUEBLER CHRISTOPHER A | Director | 03/06/2018 | 260,780 |
| Nicholson John | SVP & Chief Operating Officer | 03/07/2018 | 10,059,464 |
| Nicholson John | SVP & Chief Operating Officer | 03/06/2018 | 11,794,800 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/16/2018 | 211,082 |
| ROBIN HOWARD W | President & CEO | 02/16/2018 | 1,060,637 |
| Nicholson John | SVP & Chief Operating Officer | 02/16/2018 | 404,664 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 02/16/2018 | 288,382 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 02/16/2018 | 238,453 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 02/16/2018 | 201,212 |
| Nicholson John | SVP & Chief Operating Officer | 01/31/2018 | 1,360,800 |
| ROBIN HOWARD W | President & CEO | 01/22/2018 | 944,996 |
| ROBIN HOWARD W | President & CEO | 01/22/2018 | 6,318,308 |
| WINGER DENNIS L | Director | 01/04/2018 | 403,988 |
| KUEBLER CHRISTOPHER A | Director | 01/02/2018 | 427,800 |
| KUEBLER CHRISTOPHER A | Director | 01/02/2018 | 1,759,800 |
| ROBIN HOWARD W | President & CEO | 12/13/2017 | 944,996 |
| ROBIN HOWARD W | President & CEO | 12/13/2017 | 4,640,815 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/16/2017 | 233,932 |
| ROBIN HOWARD W | President & CEO | 11/16/2017 | 799,192 |
| Nicholson John | SVP & Chief Operating Officer | 11/16/2017 | 292,803 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 11/16/2017 | 296,253 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/16/2017 | 247,555 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 11/16/2017 | 222,123 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/16/2017 | 211,508 |
| Nicholson John | SVP & Chief Operating Officer | 11/13/2017 | 231,000 |
| Nicholson John | SVP & Chief Operating Officer | 11/13/2017 | 601,080 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/07/2017 | 626,260 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/06/2017 | 54,701 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/06/2017 | 128,283 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/07/2017 | 718,648 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/06/2017 | 199,310 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/08/2017 | 2,859,000 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/06/2017 | 522,432 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/08/2017 | 9,027,000 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/07/2017 | 1,944,044 |
| ROBIN HOWARD W | President & CEO | 11/01/2017 | 945,008 |
| ROBIN HOWARD W | President & CEO | 11/01/2017 | 1,964,182 |
| ROBIN HOWARD W | President & CEO | 10/09/2017 | 944,996 |
| ROBIN HOWARD W | President & CEO | 10/09/2017 | 2,016,659 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 10/05/2017 | 81,062 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 10/05/2017 | 189,575 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 10/05/2017 | 416,242 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 10/05/2017 | 1,090,615 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 10/02/2017 | 1,360,800 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 10/02/2017 | 2,934,000 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 10/02/2017 | 626,012 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 09/29/2017 | 477,988 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 10/02/2017 | 1,372,804 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 09/29/2017 | 1,040,836 |
| Lingnau Lutz | Director | 09/22/2017 | 109,850 |
| KUEBLER CHRISTOPHER A | Director | 09/22/2017 | 87,440 |
| CHESS ROBERT | Director | 09/21/2017 | 139,008 |
| ROBIN HOWARD W | President & CEO | 09/06/2017 | 944,996 |
| ROBIN HOWARD W | President & CEO | 09/06/2017 | 1,794,993 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2017 | 51,159 |
| ROBIN HOWARD W | President & CEO | 08/16/2017 | 945,008 |
| ROBIN HOWARD W | President & CEO | 08/16/2017 | 1,766,081 |
| Nicholson John | SVP & Chief Operating Officer | 08/16/2017 | 61,380 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/16/2017 | 61,380 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 08/16/2017 | 57,110 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 08/16/2017 | 38,582 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 08/16/2017 | 32,863 |
| WHITFIELD ROY A | Director | 08/10/2017 | 628,250 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/18/2017 | 606,317 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/18/2017 | 1,158,812 |
| Lingnau Lutz | Director | 07/14/2017 | 427,800 |
| Lingnau Lutz | Director | 07/14/2017 | 622,800 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/12/2017 | 405,069 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/11/2017 | 92,615 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/11/2017 | 176,505 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 07/12/2017 | 773,813 |
| Krivulka Joseph J | Director | 06/26/2017 | 125,550 |
| Nicholson John | SVP & Chief Operating Officer | 06/07/2017 | 951,000 |
| Nicholson John | SVP & Chief Operating Officer | 06/07/2017 | 1,956,708 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/16/2017 | 51,827 |
| ROBIN HOWARD W | President & CEO | 05/16/2017 | 163,985 |
| Nicholson John | SVP & Chief Operating Officer | 05/16/2017 | 61,504 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 05/16/2017 | 62,149 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 05/16/2017 | 57,848 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 05/16/2017 | 28,347 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 05/16/2017 | 33,255 |
| CHESS ROBERT | Director | 05/15/2017 | 41,850 |
| CHESS ROBERT | Director | 05/15/2017 | 98,950 |
| CHESS ROBERT | Director | 04/17/2017 | 41,850 |
| CHESS ROBERT | Director | 04/17/2017 | 93,600 |
| Lingnau Lutz | Director | 04/07/2017 | 140,350 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/05/2017 | 953,000 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 04/05/2017 | 2,170,000 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/05/2017 | 2,466,000 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 04/05/2017 | 3,906,000 |
| KUEBLER CHRISTOPHER A | Director | 04/05/2017 | 125,550 |
| KUEBLER CHRISTOPHER A | Director | 04/05/2017 | 328,200 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 03/20/2017 | 1,120,875 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 03/20/2017 | 2,215,125 |
| WHITFIELD ROY A | Director | 03/15/2017 | 117,180 |
| CHESS ROBERT | Director | 03/14/2017 | 41,850 |
| CHESS ROBERT | Director | 03/14/2017 | 77,050 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 03/02/2017 | 1,061,988 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 03/03/2017 | 278,512 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 03/02/2017 | 2,537,716 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 03/03/2017 | 494,234 |
| Lingnau Lutz | Director | 02/21/2017 | 154,200 |
| Lingnau Lutz | Director | 02/21/2017 | 392,400 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/16/2017 | 25,820 |
| ROBIN HOWARD W | President & CEO | 02/16/2017 | 113,477 |
| Nicholson John | SVP & Chief Operating Officer | 02/16/2017 | 42,534 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 02/16/2017 | 30,997 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 02/16/2017 | 28,842 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 02/16/2017 | 19,145 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 02/16/2017 | 16,570 |
| Nicholson John | SVP & Chief Operating Officer | 02/10/2017 | 209,250 |
| ROBIN HOWARD W | President & CEO | 02/08/2017 | 406,875 |
| ROBIN HOWARD W | President & CEO | 02/08/2017 | 1,141,000 |
| Nicholson John | SVP & Chief Operating Officer | 02/03/2017 | 39,548 |
| Nicholson John | SVP & Chief Operating Officer | 02/02/2017 | 309,202 |
| Nicholson John | SVP & Chief Operating Officer | 02/03/2017 | 106,142 |
| Nicholson John | SVP & Chief Operating Officer | 02/02/2017 | 823,208 |
| ROBIN HOWARD W | President & CEO | 01/17/2017 | 406,875 |
| ROBIN HOWARD W | President & CEO | 01/17/2017 | 1,080,625 |
| ROBIN HOWARD W | President & CEO | 12/07/2016 | 406,875 |
| ROBIN HOWARD W | President & CEO | 12/07/2016 | 1,071,000 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/16/2016 | 27,725 |
| ROBIN HOWARD W | President & CEO | 11/17/2016 | 406,875 |
| ROBIN HOWARD W | President & CEO | 11/17/2016 | 1,213,625 |
| ROBIN HOWARD W | President & CEO | 11/16/2016 | 83,174 |
| Nicholson John | SVP & Chief Operating Officer | 11/16/2016 | 23,090 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 11/16/2016 | 23,090 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 11/16/2016 | 23,090 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 11/16/2016 | 11,838 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 11/16/2016 | 9,353 |
| GREER R SCOTT | Director | 10/24/2016 | 202,500 |
| ROBIN HOWARD W | President & CEO | 10/04/2016 | 406,875 |
| ROBIN HOWARD W | President & CEO | 10/04/2016 | 1,492,750 |
| WHITFIELD ROY A | Director | 09/23/2016 | 239,820 |
| Lingnau Lutz | Director | 09/15/2016 | 171,540 |
| KUEBLER CHRISTOPHER A | Director | 09/16/2016 | 143,475 |
| CHESS ROBERT | Director | 09/15/2016 | 230,520 |
| ROBIN HOWARD W | President & CEO | 09/01/2016 | 406,875 |
| ROBIN HOWARD W | President & CEO | 09/01/2016 | 1,560,125 |
| Nicholson John | SVP & Chief Operating Officer | 08/16/2016 | 58,247 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 08/16/2016 | 69,731 |
| ROBIN HOWARD W | President & CEO | 08/16/2016 | 207,507 |
| Labrucherie Gil M | SVP & Chief Financial Officer | 08/16/2016 | 58,036 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 08/16/2016 | 58,036 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 08/16/2016 | 29,589 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 08/16/2016 | 23,460 |
| CHESS ROBERT | Director | 08/01/2016 | 25,750 |
| CHESS ROBERT | Director | 08/01/2016 | 86,300 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 07/11/2016 | 465,000 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 07/11/2016 | 1,509,000 |
| CHESS ROBERT | Director | 07/01/2016 | 25,750 |
| CHESS ROBERT | Director | 07/01/2016 | 70,500 |
| CHESS ROBERT | Director | 06/01/2016 | 25,750 |
| CHESS ROBERT | Director | 06/01/2016 | 77,500 |
| Nicholson John | SVP & Chief Financial Officer | 05/16/2016 | 0 |
| Nicholson John | SVP & Chief Financial Officer | 05/17/2016 | 11,624 |
| ROBIN HOWARD W | President & CEO | 05/16/2016 | 1 |
| ROBIN HOWARD W | President & CEO | 05/17/2016 | 29,469 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 05/16/2016 | 0 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 05/17/2016 | 4,604 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 05/16/2016 | 0 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 05/17/2016 | 5,867 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 05/16/2016 | 0 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 05/17/2016 | 11,339 |
| Labrucherie Gil M | SVP & General Counsel | 05/16/2016 | 0 |
| Labrucherie Gil M | SVP & General Counsel | 05/17/2016 | 11,353 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/16/2016 | 0 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 05/17/2016 | 9,832 |
| Lingnau Lutz | Director | 04/25/2016 | 125,550 |
| Lingnau Lutz | Director | 04/25/2016 | 244,050 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 03/09/2016 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 03/09/2016 | 176,850 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 02/16/2016 | 0 |
| Gergel Ivan P. | SVP & Chief Medical Officer | 02/17/2016 | 6,628 |
| Nicholson John | SVP & Chief Financial Officer | 02/16/2016 | 0 |
| Nicholson John | SVP & Chief Financial Officer | 02/17/2016 | 11,479 |
| ROBIN HOWARD W | President & CEO | 02/16/2016 | 1 |
| ROBIN HOWARD W | President & CEO | 02/17/2016 | 25,592 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 02/16/2016 | 0 |
| Doberstein Stephen K | SVP & Chief Scientific Officer | 02/17/2016 | 4,649 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/16/2016 | 0 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/17/2016 | 8,535 |
| Labrucherie Gil M | SVP & General Counsel | 02/16/2016 | 0 |
| Labrucherie Gil M | SVP & General Counsel | 02/17/2016 | 9,858 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 02/16/2016 | 0 |
| Hora Maninder | SVP Pharma Dev & Mfg Ops | 02/17/2016 | 11,479 |
| Labrucherie Gil M | SVP & General Counsel | 02/10/2016 | 75,362 |
| Labrucherie Gil M | SVP & General Counsel | 02/10/2016 | 134,042 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/10/2016 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 02/10/2016 | 172,350 |
| ROBIN HOWARD W | President & CEO | 02/10/2016 | 430,662 |
| ROBIN HOWARD W | President & CEO | 02/10/2016 | 765,992 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 01/19/2016 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 01/19/2016 | 211,800 |
| ROBIN HOWARD W | President & CEO | 01/19/2016 | 430,669 |
| ROBIN HOWARD W | President & CEO | 01/19/2016 | 941,338 |
| Lingnau Lutz | Director | 01/20/2016 | 77,250 |
| Lingnau Lutz | Director | 01/20/2016 | 217,650 |
| Labrucherie Gil M | SVP & General Counsel | 01/19/2016 | 75,369 |
| Labrucherie Gil M | SVP & General Counsel | 01/19/2016 | 164,738 |
| Labrucherie Gil M | SVP & General Counsel | 12/03/2015 | 308,040 |
| Labrucherie Gil M | SVP & General Counsel | 12/03/2015 | 714,166 |
| ROBIN HOWARD W | President & CEO | 12/03/2015 | 837,840 |
| ROBIN HOWARD W | President & CEO | 12/03/2015 | 1,983,766 |
| KUEBLER CHRISTOPHER A | Director | 12/04/2015 | 77,250 |
| KUEBLER CHRISTOPHER A | Director | 12/04/2015 | 237,300 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 12/03/2015 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 12/03/2015 | 238,050 |
| WANG SUSAN | Director | 11/20/2015 | 418,430 |
| WANG SUSAN | Director | 11/19/2015 | 77,758 |
| WANG SUSAN | Director | 11/18/2015 | 153,162 |
| WANG SUSAN | Director | 11/20/2015 | 743,490 |
| WANG SUSAN | Director | 11/19/2015 | 227,223 |
| WANG SUSAN | Director | 11/18/2015 | 305,580 |
| ROBIN HOWARD W | President & CEO | 11/11/2015 | 837,833 |
| ROBIN HOWARD W | President & CEO | 11/11/2015 | 1,690,000 |
| Labrucherie Gil M | SVP & General Counsel | 11/11/2015 | 308,033 |
| Labrucherie Gil M | SVP & General Counsel | 11/11/2015 | 608,400 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/11/2015 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 11/11/2015 | 202,800 |
| Lingnau Lutz | Director | 10/28/2015 | 83,125 |
| Lingnau Lutz | Director | 10/28/2015 | 150,000 |
| GREER R SCOTT | Director | 10/15/2015 | 368,550 |
| ROBIN HOWARD W | President & CEO | 10/06/2015 | 837,833 |
| ROBIN HOWARD W | President & CEO | 10/06/2015 | 1,373,750 |
| Labrucherie Gil M | SVP & General Counsel | 10/06/2015 | 308,033 |
| Labrucherie Gil M | SVP & General Counsel | 10/06/2015 | 494,550 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 10/06/2015 | 99,750 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 10/06/2015 | 164,850 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 09/23/2015 | 66,500 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 09/23/2015 | 130,400 |
| ROBIN HOWARD W | President & CEO | 09/23/2015 | 837,827 |
| ROBIN HOWARD W | President & CEO | 09/23/2015 | 1,629,987 |
| Labrucherie Gil M | SVP & General Counsel | 09/23/2015 | 308,027 |
| Labrucherie Gil M | SVP & General Counsel | 09/23/2015 | 586,787 |
| WHITFIELD ROY A | Director | 09/11/2015 | 132,150 |
| Labrucherie Gil M | SVP & General Counsel | 08/13/2015 | 232,664 |
| Labrucherie Gil M | SVP & General Counsel | 08/13/2015 | 362,996 |
| ROBIN HOWARD W | President & CEO | 08/13/2015 | 407,164 |
| ROBIN HOWARD W | President & CEO | 08/13/2015 | 635,246 |
| Nicholson John | SVP & Chief Financial Officer | 08/11/2015 | 2,437,100 |
| Nicholson John | SVP & Chief Financial Officer | 08/12/2015 | 584,000 |
| Nicholson John | SVP & Chief Financial Officer | 08/11/2015 | 2,716,089 |
| Nicholson John | SVP & Chief Financial Officer | 08/12/2015 | 733,325 |
| Krivulka Joseph J | Director | 07/24/2015 | 132,150 |
| ROBIN HOWARD W | President & CEO | 07/14/2015 | 407,171 |
| ROBIN HOWARD W | President & CEO | 07/14/2015 | 687,175 |
| Labrucherie Gil M | SVP & General Counsel | 07/14/2015 | 232,671 |
| Labrucherie Gil M | SVP & General Counsel | 07/14/2015 | 392,675 |
| WANG SUSAN | Director | 06/29/2015 | 209,400 |
| WANG SUSAN | Director | 06/29/2015 | 381,000 |
| CHESS ROBERT | Director | 06/19/2015 | 132,150 |
| CHESS ROBERT | Director | 06/19/2015 | 177,150 |
| Lingnau Lutz | Director | 06/15/2015 | 166,250 |
| Lingnau Lutz | Director | 06/15/2015 | 278,750 |
| KUEBLER CHRISTOPHER A | Director | 01/13/2015 | 132,150 |
| KUEBLER CHRISTOPHER A | Director | 01/13/2015 | 240,000 |
| CHESS ROBERT | Director | 12/29/2014 | 449,580 |
| CHESS ROBERT | Director | 12/29/2014 | 452,530 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 12/22/2014 | 56,900 |
| Thomsen Jillian B. | SVP & Chief Accounting Officer | 12/22/2014 | 77,800 |
| Labrucherie Gil M | SVP & General Counsel | 12/01/2014 | 139,500 |
| Labrucherie Gil M | SVP & General Counsel | 11/28/2014 | 418,500 |
| Labrucherie Gil M | SVP & General Counsel | 12/01/2014 | 510,000 |
| Labrucherie Gil M | SVP & General Counsel | 11/28/2014 | 1,531,800 |
| ROBIN HOWARD W | President & CEO | 11/28/2014 | 983,789 |
| ROBIN HOWARD W | President & CEO | 12/01/2014 | 1,459,211 |
| ROBIN HOWARD W | President & CEO | 11/28/2014 | 2,398,867 |
| ROBIN HOWARD W | President & CEO | 12/01/2014 | 3,553,952 |
| Labrucherie Gil M | SVP & General Counsel | 11/24/2014 | 136,710 |
| Labrucherie Gil M | SVP & General Counsel | 11/24/2014 | 157,920 |
| ROBIN HOWARD W | President & CEO | 11/24/2014 | 1,928,256 |
| ROBIN HOWARD W | President & CEO | 11/25/2014 | 6,783,744 |
| ROBIN HOWARD W | President & CEO | 11/25/2014 | 7,152,832 |
| ROBIN HOWARD W | President & CEO | 11/24/2014 | 1,994,656 |
| Lingnau Lutz | Director | 11/24/2014 | 132,150 |
| Lingnau Lutz | Director | 11/24/2014 | 225,300 |
| Labrucherie Gil M | SVP & General Counsel | 11/03/2014 | 112,662 |
| Labrucherie Gil M | SVP & General Counsel | 11/03/2014 | 136,422 |
| KUEBLER CHRISTOPHER A | Director | 08/05/2013 | 142,625 |
| KUEBLER CHRISTOPHER A | Director | 08/05/2013 | 155,125 |
| WHITFIELD ROY A | Director | 08/05/2013 | 142,625 |
| WHITFIELD ROY A | Director | 08/05/2013 | 155,125 |
| KUEBLER CHRISTOPHER A | Director | 09/27/2012 | 108,250 |
| KUEBLER CHRISTOPHER A | Director | 09/27/2012 | 133,250 |
| WINGER DENNIS L | Director | 09/14/2012 | 45,908 |
| CHESS ROBERT | Director | 07/13/2012 | 146,886 |
| CHESS ROBERT | Director | 07/13/2012 | 204,009 |
| CHESS ROBERT | Director | 03/08/2011 | 40,500 |
Load More Insider Transactions
FUNDS WITH A POSITION IN NEKTAR THERAPEUTICS
| Fund | # Shares Owned | % of Portfolio | % Change | Investing Style |
|---|---|---|---|---|
| BLACKROCK INC. | 15,155,673 | 0.00043% | 157.82% | Other |
| RENAISSANCE TECHNOLOGIES LLC | 3,313,833 | 0.00697% | -28.28% | Other |
| GEODE CAPITAL MANAGEMENT, LLC | 4,112,499 | 0.00045% | 100.31% | Other |
| D. E. SHAW & CO., INC. | 346,650 | 0.0004% | -86.4% | Other |
| OCONNOR, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS (LLC) | 1,043,930 | 0.08% | 11.58% | Value |
| AQR CAPITAL MANAGEMENT LLC | 430,983 | 0.00066% | Exited | Other |
| BALYASNY ASSET MANAGEMENT L.P. | 264,063 | 0.00057% | -11.87% | Event Driven |
| ALPINE GLOBAL MANAGEMENT, LLC | 175,168 | 0.04% | New | Event Driven |
| CANDRIAM S.C.A. | 79,594 | 0.0006% | New | Other |
| TUDOR INVESTMENT CORP ET AL | 57,083 | 0.00036% | No change | Event Driven, Other |
CHANGE IN SHARES OUTSTANDING FOR NEKTAR THERAPEUTICS
STOCK BUYBACKS FOR NEKTAR THERAPEUTICS
Period of Report
Previous Period
% Change in Shares
10-K/10-Q Filings
Quarter
Load More