. (MDVN)

$81.44 0 (0.00%)

Market Cap: $0

As of 03/29/19 12:00 AM EDT. Market closed.

(MDVN)

. (MDVN)

$81.44 0 (0.00%)

Market Cap: $0

As of 03/29/19 12:00 AM EDT. Market closed.

COMPANY PROFILE
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Industry
URL
Address
.
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Industry
URL
Address
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PRICE CHART
1w
1m
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6m
YTD
1y
5y
MAX
From: To:
NEWS
KEY STATS
Open
$0
Previous Close
$81.44
Days Range
$0 - $0
52 week range
$0 - $0
Volume
0
Avg. Volume (30 days)
0
Market Cap
$0
Dividend Yield
0.00%
P/E
-
Shares Outstanding
0
Open
$0
Previous Close
$81.44
Days Range
$0 - $0
52 week range
$0 - $0
Volume
0
Avg. Volume (30 days)
0
Market Cap
$0
Dividend Yield
0.00%
P/E
-
Shares Outstanding
0

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

INSIDER TRANSACTIONS FOR
Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
BLICKENSTAFF KIM D Director Sep 21, 2016 Option Exercise $2.21 25,500 56,355 43,242 Sep 26, 2016, 04:47 PM
Hirmand Mohammad Interim Chief Medical Officer Sep 15, 2016 Option Exercise $4.47 17,560 78,523 57,523 Sep 19, 2016, 04:50 PM
Hung David President and CEO Sep 15, 2016 Option Exercise $4.88 30,754 149,981 1,564,377 Sep 19, 2016, 04:49 PM
Powell Andrew Kenneth William SVP, General Counsel & Crp Sec Jun 06, 2016 Sale $60.42 2,578 155,763 28,517 Jun 06, 2016, 08:10 PM
Bierly Rick CFO (former) May 06, 2016 Sale $60.12 6,315 379,637 29,144 May 09, 2016, 05:35 PM
Bierly Rick CFO (former) May 05, 2016 Sale $59.20 4,025 238,280 35,059 May 09, 2016, 05:35 PM
Svoronos Dawn Director Mar 14, 2016 Sale $38.90 6,000 233,400 18,234 Mar 16, 2016, 05:06 PM
Hung David President and CEO Mar 04, 2016 Sale $41.10 5,085 208,993 1,549,189 Mar 07, 2016, 08:44 PM
Hirmand Mohammad Interim Chief Medical Officer Mar 04, 2016 Sale $41.10 1,525 62,685 39,342 Mar 07, 2016, 08:44 PM
Bierly Rick Chief Financial Officer Mar 04, 2016 Sale $40.00 2,998 119,920 40,959 Mar 07, 2016, 08:43 PM
Hung David President and CEO Feb 04, 2016 Sale $31.18 6,350 197,993 1,504,654 Feb 05, 2016, 07:05 PM
Machado Clarence Patrick Director Jan 19, 2016 Option Exercise $3.37 75,000 252,525 141,156 Jan 21, 2016, 05:45 PM
Machado Clarence Patrick Director Jan 19, 2016 Sale $37.34 75,000 2,800,562 104,135 Jan 21, 2016, 05:45 PM
Lobacki Joseph M Chief Commercial Officer Jan 04, 2016 Sale $46.50 3,065 142,523 19,365 Jan 05, 2016, 06:14 PM
VERNON W ANTHONY Director Dec 14, 2015 Buy $40.69 15,000 610,350 28,704 Dec 16, 2015, 05:40 PM
Hung David President and CEO Dec 03, 2015 Sale $43.10 10,950 471,966 1,511,004 Dec 04, 2015, 04:36 PM
Hirmand Mohammad Interim Chief Medical Officer Dec 03, 2015 Sale $43.40 1,075 46,655 31,113 Dec 04, 2015, 04:35 PM
Machado Clarence Patrick Director Sep 25, 2015 Option Exercise $4.69 71,980 337,766 138,136 Sep 28, 2015, 07:14 PM
Machado Clarence Patrick Director Sep 25, 2015 Sale $42.36 71,980 3,049,106 125,536 Sep 28, 2015, 07:14 PM
Svoronos Dawn Director Sep 08, 2015 Sale $89.15 3,100 276,365 12,117 Sep 08, 2015, 07:39 PM
Machado Clarence Patrick Director Jun 04, 2015 Option Exercise $9.39 36,000 337,860 67,500 Jun 08, 2015, 06:25 PM
Machado Clarence Patrick Director Jun 04, 2015 Sale $117.43 36,000 4,227,478 50,900 Jun 08, 2015, 06:25 PM
Bierly Rick Chief Financial Officer May 20, 2015 Sale $130.00 1,000 130,000 14,841 May 20, 2015, 06:40 PM
Bierly Rick Chief Financial Officer May 08, 2015 Sale $125.00 385 48,125 15,841 May 12, 2015, 08:07 PM
Bierly Rick Chief Financial Officer May 04, 2015 Sale $124.70 2,170 270,603 17,841 May 06, 2015, 07:42 PM
Bierly Rick Chief Financial Officer May 05, 2015 Sale $125.00 1,615 201,875 16,226 May 06, 2015, 07:42 PM
Bierly Rick Chief Financial Officer Apr 15, 2015 Option Exercise $58.10 3,000 174,300 23,011 Apr 16, 2015, 05:31 PM
Bierly Rick Chief Financial Officer Apr 15, 2015 Sale $132.20 3,000 396,600 20,011 Apr 16, 2015, 05:31 PM
Rhodes Jennifer J GC & Corporate Secretary Mar 16, 2015 Sale $130.92 1,390 181,979 11,090 Mar 17, 2015, 05:37 PM
Svoronos Dawn Director Mar 02, 2015 Sale $119.75 3,350 401,163 13,639 Mar 04, 2015, 09:22 PM
Rhodes Jennifer J GC & Corporate Secretary Mar 02, 2015 Option Exercise $47.48 2,000 94,960 14,480 Mar 02, 2015, 09:16 PM
Rhodes Jennifer J GC & Corporate Secretary Mar 02, 2015 Sale $122.00 2,000 244,000 12,480 Mar 02, 2015, 09:16 PM
Hung David President and CEO Mar 02, 2015 Sale $120.83 100,891 12,190,608 793,168 Mar 02, 2015, 09:15 PM
FALBERG KATHRYN E Director Feb 27, 2015 Buy $117.67 25,000 2,941,684 25,000 Mar 02, 2015, 09:13 PM
Rhodes Jennifer J GC & Corporate Secretary Feb 26, 2015 Option Exercise $47.48 2,000 94,960 14,480 Feb 27, 2015, 04:56 PM
Rhodes Jennifer J GC & Corporate Secretary Feb 26, 2015 Sale $119.29 3,089 368,502 13,391 Feb 27, 2015, 04:56 PM
Hung David President and CEO Feb 26, 2015 Sale $120.12 19,109 2,295,373 861,868 Feb 27, 2015, 04:55 PM
Machado Clarence Patrick Director Feb 10, 2015 Option Exercise $9.39 36,000 337,860 67,500 Feb 12, 2015, 04:21 PM
Machado Clarence Patrick Director Feb 10, 2015 Sale $103.89 36,000 3,739,984 66,800 Feb 12, 2015, 04:21 PM
Hung David President and CEO Feb 04, 2015 Sale $100.48 3,190 320,518 861,868 Feb 06, 2015, 07:04 PM
Rhodes Jennifer J GC & Corporate Secretary Feb 04, 2015 Sale $100.85 610 61,518 8,980 Feb 06, 2015, 07:03 PM
Machado Clarence Patrick Director Jan 27, 2015 Option Exercise $9.63 36,000 346,613 67,500 Jan 29, 2015, 05:34 PM
Machado Clarence Patrick Director Jan 27, 2015 Sale $105.32 36,000 3,791,392 50,300 Jan 29, 2015, 05:34 PM
Hung David President and CEO Jan 20, 2015 Sale $108.14 100,000 10,814,241 944,192 Jan 22, 2015, 06:33 PM
Seely Lynn Chief Medical Officer Dec 19, 2014 Option Exercise $10.18 31,340 318,949 91,194 Dec 22, 2014, 07:42 PM
Rhodes Jennifer J GC & Corporate Secretary Dec 03, 2014 Sale $113.00 910 102,830 9,590 Dec 04, 2014, 04:54 PM
Machado Clarence Patrick Director Dec 03, 2014 Sale $113.00 1,580 178,540 31,500 Dec 04, 2014, 04:53 PM
Hung David President and CEO Dec 03, 2014 Sale $113.00 5,420 612,460 965,058 Dec 04, 2014, 04:52 PM
Seely Lynn Chief Medical Officer Oct 22, 2014 Option Exercise $10.59 5,000 52,925 64,854 Oct 23, 2014, 06:54 PM
Seely Lynn Chief Medical Officer Oct 22, 2014 Sale $99.03 5,000 495,141 59,854 Oct 23, 2014, 06:54 PM
Seely Lynn Chief Medical Officer Oct 16, 2014 Option Exercise $10.59 5,000 52,925 64,854 Oct 17, 2014, 04:39 PM
Seely Lynn Chief Medical Officer Oct 15, 2014 Option Exercise $8.00 24,346 194,737 84,200 Oct 17, 2014, 04:39 PM
Seely Lynn Chief Medical Officer Oct 16, 2014 Sale $93.97 5,000 469,850 59,854 Oct 17, 2014, 04:39 PM
Seely Lynn Chief Medical Officer Oct 15, 2014 Sale $89.11 24,346 2,169,363 81,200 Oct 17, 2014, 04:39 PM
Seely Lynn Chief Medical Officer Sep 18, 2014 Option Exercise $10.59 25,000 264,625 84,022 Sep 18, 2014, 08:36 PM
Seely Lynn Chief Medical Officer Sep 17, 2014 Option Exercise $8.46 30,000 253,800 89,022 Sep 18, 2014, 08:36 PM
Seely Lynn Chief Medical Officer Sep 18, 2014 Sale $99.81 25,000 2,495,158 66,222 Sep 18, 2014, 08:36 PM
Seely Lynn Chief Medical Officer Sep 17, 2014 Sale $97.36 30,000 2,920,727 75,722 Sep 18, 2014, 08:36 PM
Seely Lynn Chief Medical Officer Sep 09, 2014 Option Exercise $10.59 20,000 211,700 79,022 Sep 11, 2014, 06:04 PM
Seely Lynn Chief Medical Officer Sep 09, 2014 Sale $94.60 20,000 1,892,016 64,209 Sep 11, 2014, 06:04 PM
Seely Lynn Chief Medical Officer Aug 26, 2014 Option Exercise $10.59 5,700 60,335 64,722 Aug 28, 2014, 07:54 PM
Seely Lynn Chief Medical Officer Aug 27, 2014 Option Exercise $10.59 14,300 151,366 73,322 Aug 28, 2014, 07:54 PM
Seely Lynn Chief Medical Officer Aug 26, 2014 Sale $88.95 5,700 507,032 59,022 Aug 28, 2014, 07:54 PM
Seely Lynn Chief Medical Officer Aug 27, 2014 Sale $89.61 14,300 1,281,423 61,622 Aug 28, 2014, 07:54 PM
Seely Lynn Chief Medical Officer Aug 13, 2014 Option Exercise $8.39 20,000 167,825 79,022 Aug 14, 2014, 08:00 PM
Seely Lynn Chief Medical Officer Aug 13, 2014 Sale $83.62 20,000 1,672,456 68,022 Aug 14, 2014, 08:00 PM
Seely Lynn Chief Medical Officer Aug 12, 2014 Option Exercise $9.39 12,500 117,313 71,522 Aug 12, 2014, 08:49 PM
Seely Lynn Chief Medical Officer Aug 08, 2014 Option Exercise $9.39 13,000 122,005 72,022 Aug 12, 2014, 08:49 PM
Seely Lynn Chief Medical Officer Aug 12, 2014 Sale $84.01 12,500 1,050,125 59,022 Aug 12, 2014, 08:49 PM
Seely Lynn Chief Medical Officer Aug 08, 2014 Sale $82.06 13,000 1,066,821 67,722 Aug 12, 2014, 08:49 PM
Seely Lynn Chief Medical Officer Jul 22, 2014 Option Exercise $6.74 7,500 50,513 66,522 Jul 23, 2014, 06:19 PM
Seely Lynn Chief Medical Officer Jul 22, 2014 Sale $73.96 7,500 554,710 59,022 Jul 23, 2014, 06:19 PM
Seely Lynn Chief Medical Officer Jul 02, 2014 Option Exercise $9.39 12,000 112,620 71,022 Jul 07, 2014, 07:35 PM
Seely Lynn Chief Medical Officer Jul 02, 2014 Sale $79.02 12,000 948,194 59,022 Jul 07, 2014, 07:35 PM
Seely Lynn Chief Medical Officer Jun 03, 2014 Option Exercise $6.74 7,500 50,513 66,522 Jun 19, 2014, 04:35 PM
Seely Lynn Chief Medical Officer Jun 18, 2014 Option Exercise $6.74 7,500 50,513 66,522 Jun 19, 2014, 04:35 PM
Seely Lynn Chief Medical Officer Jun 03, 2014 Sale $74.50 7,500 558,760 60,022 Jun 19, 2014, 04:35 PM
Seely Lynn Chief Medical Officer Jun 18, 2014 Sale $75.00 7,500 562,530 61,022 Jun 19, 2014, 04:35 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 18, 2014 Option Exercise $10.59 40,000 423,400 70,830 Feb 19, 2014, 04:58 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 18, 2014 Sale $82.79 40,000 3,311,646 67,230 Feb 19, 2014, 04:58 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 11, 2014 Option Exercise $10.59 40,000 423,400 70,830 Feb 12, 2014, 05:34 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 11, 2014 Sale $80.83 40,000 3,233,121 66,330 Feb 12, 2014, 05:34 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 05, 2014 Option Exercise $10.59 40,000 423,400 70,830 Feb 06, 2014, 05:24 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 05, 2014 Sale $73.46 40,000 2,938,574 55,430 Feb 06, 2014, 05:24 PM
Machado Clarence Patrick Chief Business Officer and CFO Jan 28, 2014 Option Exercise $10.59 40,000 423,400 70,830 Jan 29, 2014, 07:33 PM
Machado Clarence Patrick Chief Business Officer and CFO Jan 28, 2014 Sale $75.43 40,000 3,017,122 62,530 Jan 29, 2014, 07:33 PM
Hung David President and CEO Jan 27, 2014 Option Exercise $5.88 150,000 882,000 1,100,204 Jan 28, 2014, 05:39 PM
Hung David President and CEO Jan 27, 2014 Sale $73.50 150,000 11,025,357 1,089,204 Jan 28, 2014, 05:39 PM
Machado Clarence Patrick Chief Business Officer and CFO Jan 21, 2014 Option Exercise $10.59 40,000 423,400 70,830 Jan 23, 2014, 07:24 PM
Machado Clarence Patrick Chief Business Officer and CFO Jan 21, 2014 Sale $76.29 40,000 3,051,627 45,644 Jan 23, 2014, 07:24 PM
Rhodes Jennifer J GC & Chief Compliance Officer Jan 21, 2014 Option Exercise $47.48 14,000 664,720 20,000 Jan 23, 2014, 07:23 PM
Rhodes Jennifer J GC & Chief Compliance Officer Jan 21, 2014 Sale $76.28 14,000 1,067,949 10,600 Jan 23, 2014, 07:23 PM
Machado Clarence Patrick Chief Business Officer and CFO Dec 03, 2013 Sale $62.66 5,425 339,910 30,830 Dec 04, 2013, 06:18 PM
Hung David President and CEO Dec 03, 2013 Sale $62.61 15,050 942,288 950,204 Dec 04, 2013, 06:16 PM
BLICKENSTAFF KIM D Director Nov 21, 2013 Option Exercise $11.20 30,000 336,150 33,557 Nov 25, 2013, 04:52 PM
BLICKENSTAFF KIM D Director Nov 21, 2013 Sale $61.17 30,000 1,835,100 3,557 Nov 25, 2013, 04:52 PM
BLICKENSTAFF KIM D Director Nov 18, 2013 Option Exercise $6.97 30,000 208,950 33,557 Nov 20, 2013, 04:44 PM
BLICKENSTAFF KIM D Director Nov 18, 2013 Sale $61.72 30,000 1,851,703 25,457 Nov 20, 2013, 04:44 PM
Machado Clarence Patrick Chief Business Officer and CFO Nov 07, 2013 Option Exercise $0.77 2,765 2,143 36,255 Nov 12, 2013, 05:28 PM
Hung David President and CEO Nov 07, 2013 Option Exercise $0.77 19,608 15,196 965,254 Nov 12, 2013, 05:27 PM
Cohen Cheryl Chief Commercial Officer Oct 24, 2013 Option Exercise $9.60 25,000 240,125 50,439 Oct 28, 2013, 04:55 PM
Cohen Cheryl Chief Commercial Officer Oct 23, 2013 Option Exercise $9.60 25,000 240,125 50,439 Oct 28, 2013, 04:55 PM
Cohen Cheryl Chief Commercial Officer Oct 24, 2013 Sale $65.45 25,000 1,636,346 27,439 Oct 28, 2013, 04:55 PM
Cohen Cheryl Chief Commercial Officer Oct 23, 2013 Sale $63.05 25,000 1,576,245 25,439 Oct 28, 2013, 04:55 PM
Cohen Cheryl Chief Commercial Officer Aug 02, 2013 Option Exercise $9.60 25,000 240,125 50,439 Aug 06, 2013, 05:00 PM
Cohen Cheryl Chief Commercial Officer Aug 02, 2013 Sale $59.31 25,000 1,482,820 25,439 Aug 06, 2013, 05:00 PM
Hung David President and CEO Jul 05, 2013 Sale $55.45 30,885 1,712,718 1,831,595 Jul 09, 2013, 06:07 PM
Cohen Cheryl Chief Commercial Officer Jul 03, 2013 Option Exercise $9.60 25,000 240,125 50,439 Jul 08, 2013, 07:44 PM
Cohen Cheryl Chief Commercial Officer Jul 03, 2013 Sale $54.01 25,000 1,350,250 25,439 Jul 08, 2013, 07:44 PM
Hung David President and CEO Apr 23, 2013 Sale $55.00 1,615 88,825 1,862,480 Apr 25, 2013, 05:48 PM
Hung David President and CEO Apr 19, 2013 Sale $55.13 57,465 3,168,247 1,873,930 Apr 22, 2013, 04:43 PM
Hung David President and CEO Apr 18, 2013 Sale $55.00 200 11,000 1,931,395 Apr 22, 2013, 04:43 PM
Hung David President and CEO Apr 22, 2013 Sale $55.02 9,835 541,156 1,864,095 Apr 22, 2013, 04:43 PM
Hung David President and CEO Apr 11, 2013 Sale $52.62 50,000 2,631,030 1,931,595 Apr 15, 2013, 05:03 PM
Hung David President and CEO Apr 05, 2013 Sale $50.17 50,000 2,508,500 1,981,595 Apr 09, 2013, 06:06 PM
VERNON W ANTHONY Director Mar 15, 2013 Option Exercise $8.17 60,000 490,200 66,832 Mar 19, 2013, 05:19 PM
VERNON W ANTHONY Director Mar 15, 2013 Sale $45.91 60,000 2,754,600 6,832 Mar 19, 2013, 05:19 PM
BLICKENSTAFF KIM D Director Mar 07, 2013 Option Exercise $9.38 60,000 562,500 60,000 Mar 11, 2013, 05:06 PM
BLICKENSTAFF KIM D Director Mar 08, 2013 Sale $47.21 44,800 2,114,976 13,500 Mar 11, 2013, 05:06 PM
BLICKENSTAFF KIM D Director Mar 07, 2013 Sale $46.18 15,200 701,936 44,800 Mar 11, 2013, 05:06 PM
Machado Clarence Patrick Chief Business Officer and CFO Dec 10, 2012 Option Exercise $54.40 5,125 278,825 43,084 Dec 11, 2012, 07:00 PM
Hung David President and CEO Dec 10, 2012 Sale $54.42 10,246 557,553 2,036,910 Dec 11, 2012, 06:58 PM
Bailey Gregory Director Oct 30, 2012 Option Exercise $5.68 243,771 1,384,869 691,101 Nov 01, 2012, 08:32 PM
Bailey Gregory Director Oct 24, 2012 Sale $53.60 16,800 900,480 447,330 Oct 26, 2012, 04:30 PM
Bailey Gregory Director Oct 16, 2012 Sale $53.50 3,200 171,200 464,130 Oct 18, 2012, 04:55 PM
Bailey Gregory Director Oct 05, 2012 Sale $58.42 20,000 1,168,400 467,330 Oct 09, 2012, 05:37 PM
Bailey Gregory Director Oct 04, 2012 Sale $57.77 20,000 1,155,400 487,330 Oct 09, 2012, 05:37 PM
Hung David President and CEO Oct 04, 2012 Sale $57.92 50,000 2,895,780 2,010,841 Oct 05, 2012, 04:40 PM
Bailey Gregory Director Oct 02, 2012 Sale $56.39 30,000 1,691,717 511,656 Oct 03, 2012, 06:49 PM
Machado Clarence Patrick Chief Business Officer and CFO Oct 03, 2012 Option Exercise $6.74 5,100 34,374 41,649 Oct 03, 2012, 06:49 PM
Machado Clarence Patrick Chief Business Officer and CFO Oct 02, 2012 Option Exercise $6.44 9,400 60,490 45,949 Oct 03, 2012, 06:49 PM
Machado Clarence Patrick Chief Business Officer and CFO Oct 01, 2012 Option Exercise $5.88 5,500 32,340 42,049 Oct 03, 2012, 06:49 PM
Machado Clarence Patrick Chief Business Officer and CFO Oct 02, 2012 Sale $57.08 9,400 536,508 36,549 Oct 03, 2012, 06:49 PM
Machado Clarence Patrick Chief Business Officer and CFO Oct 01, 2012 Sale $57.04 5,500 313,739 36,549 Oct 03, 2012, 06:49 PM
Machado Clarence Patrick Chief Business Officer and CFO Oct 03, 2012 Sale $51.08 5,100 260,483 36,549 Oct 03, 2012, 06:49 PM
Hung David President and CEO Sep 28, 2012 Option Exercise $56.35 17,707 997,789 2,060,841 Oct 03, 2012, 04:53 PM
Cohen Cheryl Chief Commercial Officer Sep 28, 2012 Option Exercise $56.35 4,361 245,742 16,439 Oct 03, 2012, 04:52 PM
Machado Clarence Patrick Chief Business Officer and CFO Sep 28, 2012 Option Exercise $56.35 6,473 364,754 36,549 Oct 03, 2012, 04:52 PM
Machado Clarence Patrick Chief Business Officer and CFO Sep 28, 2012 Option Exercise $56.35 6,473 364,754 15,038 Oct 02, 2012, 05:39 PM
Cohen Cheryl Chief Commercial Officer Sep 28, 2012 Option Exercise $56.35 4,361 245,742 6,039 Oct 02, 2012, 05:38 PM
Hung David President and CEO Sep 28, 2012 Option Exercise $56.35 17,707 997,789 1,021,567 Oct 02, 2012, 05:37 PM
Bailey Gregory Director Sep 27, 2012 Sale $56.20 50,000 2,810,200 557,330 Sep 27, 2012, 06:44 PM
Bailey Gregory Director Sep 25, 2012 Sale $54.78 10,000 547,800 587,330 Sep 27, 2012, 06:44 PM
Adams Daniel Director Sep 25, 2012 Option Exercise $6.97 5,000 34,850 5,000 Sep 27, 2012, 06:43 PM
Adams Daniel Director Sep 27, 2012 Option Exercise $8.71 83,038 723,375 83,038 Sep 27, 2012, 06:43 PM
Adams Daniel Director Sep 25, 2012 Sale $55.00 5,000 275,009 0 Sep 27, 2012, 06:43 PM
Adams Daniel Director Sep 27, 2012 Sale $55.73 83,038 4,627,749 0 Sep 27, 2012, 06:43 PM
Machado Clarence Patrick Chief Business Officer and CFO Sep 07, 2012 Option Exercise $11.76 20,000 235,200 41,511 Sep 11, 2012, 04:53 PM
Machado Clarence Patrick Chief Business Officer and CFO Sep 07, 2012 Sale $105.74 20,000 2,114,858 28,111 Sep 11, 2012, 04:53 PM
Bailey Gregory Director Sep 06, 2012 Sale $108.24 28,606 3,096,402 316,655 Sep 10, 2012, 05:57 PM
Bailey Gregory Director Sep 07, 2012 Sale $108.02 1,550 167,433 299,772 Sep 10, 2012, 05:57 PM
Hung David President and CEO Sep 04, 2012 Sale $111.16 25,000 2,779,009 1,061,774 Sep 05, 2012, 05:51 PM
Seely Lynn Chief Medical Officer Jul 25, 2012 Option Exercise $34.56 2,400 82,944 23,911 Jul 27, 2012, 04:41 PM
Seely Lynn Chief Medical Officer Jul 26, 2012 Option Exercise $34.56 37,600 1,299,456 59,111 Jul 27, 2012, 04:41 PM
Seely Lynn Chief Medical Officer Jul 26, 2012 Sale $99.73 37,600 3,749,815 27,017 Jul 27, 2012, 04:41 PM
Seely Lynn Chief Medical Officer Jul 25, 2012 Sale $98.01 2,400 235,218 21,511 Jul 27, 2012, 04:41 PM
Hung David President and CEO Jul 03, 2012 Sale $95.05 25,000 2,376,205 1,064,274 Jul 09, 2012, 05:04 PM
Machado Clarence Patrick Chief Business Officer and CFO Jul 02, 2012 Option Exercise $11.76 10,000 117,600 31,511 Jul 05, 2012, 06:05 PM
Machado Clarence Patrick Chief Business Officer and CFO Jul 02, 2012 Sale $94.11 10,000 941,100 21,511 Jul 05, 2012, 06:05 PM
Bailey Gregory Director Jul 03, 2012 Sale $95.17 2,000 190,340 328,821 Jul 03, 2012, 05:28 PM
Bailey Gregory Director Jul 02, 2012 Sale $93.40 5,500 513,700 330,821 Jul 03, 2012, 05:28 PM
Bailey Gregory Director Jun 29, 2012 Sale $89.87 11,000 988,525 345,821 Jul 03, 2012, 05:28 PM
VERNON W ANTHONY Director Jun 14, 2012 Option Exercise $4.45 43,206 192,267 46,622 Jun 15, 2012, 06:48 PM
VERNON W ANTHONY Director Jun 13, 2012 Option Exercise $4.45 27,600 122,820 31,016 Jun 15, 2012, 06:48 PM
VERNON W ANTHONY Director Jun 15, 2012 Option Exercise $4.45 31,094 138,368 34,510 Jun 15, 2012, 06:48 PM
VERNON W ANTHONY Director Jun 13, 2012 Sale $84.72 27,600 2,338,249 13,417 Jun 15, 2012, 06:48 PM
VERNON W ANTHONY Director Jun 15, 2012 Sale $82.46 31,094 2,564,019 8,316 Jun 15, 2012, 06:48 PM
VERNON W ANTHONY Director Jun 14, 2012 Sale $82.54 43,206 3,566,131 9,456 Jun 15, 2012, 06:48 PM
Adams Daniel Director Jun 14, 2012 Option Exercise $3.75 38,100 142,875 38,100 Jun 15, 2012, 06:47 PM
Adams Daniel Director Jun 13, 2012 Option Exercise $5.50 27,500 151,281 27,500 Jun 15, 2012, 06:47 PM
Adams Daniel Director Jun 15, 2012 Option Exercise $3.75 24,400 91,500 24,400 Jun 15, 2012, 06:47 PM
Adams Daniel Director Jun 13, 2012 Sale $84.71 27,500 2,329,418 11,103 Jun 15, 2012, 06:47 PM
Adams Daniel Director Jun 15, 2012 Sale $82.28 24,400 2,007,632 0 Jun 15, 2012, 06:47 PM
Adams Daniel Director Jun 14, 2012 Sale $82.48 38,100 3,142,584 4,700 Jun 15, 2012, 06:47 PM
BLICKENSTAFF KIM D Director Jun 13, 2012 Option Exercise $3.75 17,700 66,375 17,700 Jun 15, 2012, 06:46 PM
BLICKENSTAFF KIM D Director Jun 14, 2012 Option Exercise $3.75 24,200 90,750 24,200 Jun 15, 2012, 06:46 PM
BLICKENSTAFF KIM D Director Jun 13, 2012 Sale $84.76 17,700 1,500,174 6,200 Jun 15, 2012, 06:46 PM
BLICKENSTAFF KIM D Director Jun 14, 2012 Sale $82.30 24,200 1,991,660 0 Jun 15, 2012, 06:46 PM
Machado Clarence Patrick Chief Business Officer and CFO May 22, 2012 Option Exercise $11.76 600 7,056 22,111 May 24, 2012, 07:13 PM
Machado Clarence Patrick Chief Business Officer and CFO May 24, 2012 Option Exercise $11.76 9,400 110,544 30,911 May 24, 2012, 07:13 PM
Machado Clarence Patrick Chief Business Officer and CFO May 22, 2012 Sale $89.16 600 53,496 21,511 May 24, 2012, 07:13 PM
Machado Clarence Patrick Chief Business Officer and CFO May 24, 2012 Sale $89.17 9,400 838,213 21,511 May 24, 2012, 07:13 PM
Seely Lynn Chief Medical Officer May 22, 2012 Option Exercise $13.47 12,500 168,375 34,011 May 24, 2012, 07:12 PM
Seely Lynn Chief Medical Officer May 22, 2012 Sale $88.51 12,500 1,106,334 21,511 May 24, 2012, 07:12 PM
Seely Lynn Chief Medical Officer May 17, 2012 Option Exercise $21.17 14,360 304,001 35,871 May 21, 2012, 04:27 PM
Seely Lynn Chief Medical Officer May 17, 2012 Sale $88.01 14,360 1,263,829 21,511 May 21, 2012, 04:27 PM
Seely Lynn Chief Medical Officer May 14, 2012 Option Exercise $21.17 35,640 754,499 57,151 May 16, 2012, 05:28 PM
Seely Lynn Chief Medical Officer May 14, 2012 Sale $88.08 35,640 3,139,029 21,511 May 16, 2012, 05:28 PM
Hung David President and CEO May 14, 2012 Sale $85.86 25,000 2,146,435 1,089,274 May 16, 2012, 05:26 PM
Machado Clarence Patrick Chief Business Officer and CFO May 14, 2012 Option Exercise $11.76 10,000 117,600 31,511 May 16, 2012, 05:25 PM
Machado Clarence Patrick Chief Business Officer and CFO May 14, 2012 Sale $84.31 10,000 843,100 21,511 May 16, 2012, 05:25 PM
Machado Clarence Patrick Chief Business Officer and CFO Apr 27, 2012 Option Exercise $11.76 10,000 117,600 31,511 May 01, 2012, 05:08 PM
Machado Clarence Patrick Chief Business Officer and CFO Apr 27, 2012 Sale $80.16 10,000 801,630 21,511 May 01, 2012, 05:08 PM
Seely Lynn Chief Medical Officer Mar 08, 2012 Option Exercise $73.01 40,000 2,920,314 40,281 Mar 12, 2012, 05:12 PM
Seely Lynn Chief Medical Officer Mar 08, 2012 Option Exercise $9.32 106,000 988,400 133,066 Mar 12, 2012, 05:12 PM
Seely Lynn Chief Medical Officer Mar 08, 2012 Sale $70.11 71,555 5,016,647 79,783 Mar 12, 2012, 05:12 PM
Machado Clarence Patrick Chief Business Officer and CFO Mar 08, 2012 Option Exercise $11.76 10,000 117,600 31,511 Mar 12, 2012, 05:11 PM
Machado Clarence Patrick Chief Business Officer and CFO Mar 08, 2012 Sale $75.10 10,000 751,000 21,511 Mar 12, 2012, 05:11 PM
Hung David President and CEO Feb 07, 2012 Sale $71.68 43,471 3,115,795 1,209,474 Feb 09, 2012, 06:55 PM
Hung David President and CEO Feb 08, 2012 Sale $69.06 56,529 3,903,693 1,148,803 Feb 09, 2012, 06:55 PM
BLICKENSTAFF KIM D Director Feb 08, 2012 Option Exercise $3.75 6,300 23,625 6,300 Feb 09, 2012, 06:55 PM
BLICKENSTAFF KIM D Director Feb 07, 2012 Option Exercise $3.75 13,700 51,375 13,700 Feb 09, 2012, 06:55 PM
BLICKENSTAFF KIM D Director Feb 08, 2012 Sale $69.19 6,300 435,926 4,100 Feb 09, 2012, 06:55 PM
BLICKENSTAFF KIM D Director Feb 07, 2012 Sale $71.62 13,700 981,201 12,600 Feb 09, 2012, 06:55 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 08, 2012 Option Exercise $11.76 19,193 225,710 57,093 Feb 09, 2012, 06:54 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 07, 2012 Option Exercise $11.76 16,391 192,758 80,807 Feb 09, 2012, 06:54 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 08, 2012 Sale $69.06 57,093 3,942,916 37,193 Feb 09, 2012, 06:54 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 07, 2012 Sale $71.68 42,907 3,075,416 76,307 Feb 09, 2012, 06:54 PM
Bailey Gregory Director Nov 09, 2011 Buy $40.80 3,000 122,399 347,321 Nov 14, 2011, 06:12 PM
QVT Associates GP LLC 10% Owner Jun 07, 2011 Sale $22.62 368,147 8,329,089 3,595,791 Jun 09, 2011, 05:01 PM
QVT Associates GP LLC 10% Owner Jun 06, 2011 Sale $22.21 127,834 2,838,789 3,773,333 Jun 06, 2011, 07:30 PM
QVT Associates GP LLC 10% Owner Jun 03, 2011 Sale $22.68 90,169 2,045,355 3,838,288 Jun 06, 2011, 07:30 PM
QVT Associates GP LLC 10% Owner Jun 02, 2011 Sale $22.84 50,752 1,158,930 3,943,531 Jun 06, 2011, 07:30 PM
Machado Clarence Patrick Chief Business Officer and CFO Jun 01, 2011 Sale $24.15 28,200 681,030 58,861 Jun 03, 2011, 06:26 PM
PALEKAR ROHAN Chief Commercial Officer Apr 20, 2011 Option Exercise $15.71 12,500 196,375 29,166 Apr 21, 2011, 05:17 PM
PALEKAR ROHAN Chief Commercial Officer Apr 20, 2011 Sale $22.63 12,500 282,825 16,666 Apr 21, 2011, 05:17 PM
PALEKAR ROHAN Chief Commercial Officer Mar 21, 2011 Sale $16.05 7,500 120,375 16,666 Mar 22, 2011, 04:36 PM
Seely Lynn Chief Medical Officer Mar 15, 2011 Option Exercise $3.60 50,000 180,000 66,666 Mar 17, 2011, 05:14 PM
Seely Lynn Chief Medical Officer Mar 15, 2011 Sale $16.48 50,000 823,885 16,666 Mar 17, 2011, 05:14 PM
Hung David President and CEO Feb 23, 2011 Option Exercise $16.96 50,000 848,150 1,232,974 Feb 24, 2011, 06:26 PM
Hung David President and CEO Feb 22, 2011 Option Exercise $17.20 100,000 1,719,990 1,282,974 Feb 24, 2011, 06:26 PM
Hung David President and CEO Feb 24, 2011 Option Exercise $16.41 50,000 820,430 1,182,974 Feb 24, 2011, 06:26 PM
Seely Lynn Chief Medical Officer Feb 15, 2011 Option Exercise $3.60 50,000 180,000 66,666 Feb 16, 2011, 05:37 PM
Seely Lynn Chief Medical Officer Feb 15, 2011 Sale $17.97 50,000 898,320 16,666 Feb 16, 2011, 05:37 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 09, 2011 Sale $15.55 2,800 43,530 101,061 Feb 11, 2011, 04:55 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 10, 2011 Sale $17.06 14,000 238,819 94,061 Feb 11, 2011, 04:55 PM
Machado Clarence Patrick Chief Business Officer and CFO Feb 07, 2011 Sale $15.51 4,200 65,130 120,527 Feb 08, 2011, 08:11 PM
Seely Lynn Chief Medical Officer Jan 19, 2011 Option Exercise $3.60 25,000 90,000 41,666 Jan 20, 2011, 06:12 PM
Seely Lynn Chief Medical Officer Jan 18, 2011 Option Exercise $3.60 25,000 90,000 41,666 Jan 20, 2011, 06:12 PM
Seely Lynn Chief Medical Officer Jan 19, 2011 Sale $14.45 25,000 361,212 16,666 Jan 20, 2011, 06:12 PM
Seely Lynn Chief Medical Officer Jan 18, 2011 Sale $15.59 25,000 389,740 16,666 Jan 20, 2011, 06:12 PM
QVT Associates GP LLC 10% Owner Nov 29, 2010 Buy $11.00 200 2,200 3,968,631 Dec 01, 2010, 05:18 PM
QVT Associates GP LLC 10% Owner Nov 23, 2010 Buy $10.99 2,100 23,079 3,968,431 Nov 26, 2010, 02:20 PM
QVT Associates GP LLC 10% Owner Nov 17, 2010 Buy $11.00 400 4,400 3,966,331 Nov 19, 2010, 04:47 PM
QVT Associates GP LLC 10% Owner Oct 27, 2010 Buy $11.42 14,901 170,169 3,965,931 Oct 28, 2010, 07:31 PM
QVT Associates GP LLC 10% Owner Oct 26, 2010 Buy $11.44 40,914 468,056 3,951,030 Oct 28, 2010, 07:31 PM
QVT Associates GP LLC 10% Owner Oct 22, 2010 Buy $11.28 134,470 1,516,796 3,887,390 Oct 26, 2010, 07:21 PM
QVT Associates GP LLC 10% Owner Oct 25, 2010 Buy $11.28 22,726 256,349 3,910,116 Oct 26, 2010, 07:21 PM
QVT Associates GP LLC 10% Owner Sep 17, 2010 Buy $11.49 8,823 101,376 3,752,920 Sep 20, 2010, 05:17 PM
QVT Associates GP LLC 10% Owner Sep 16, 2010 Buy $11.49 20,827 239,242 3,744,097 Sep 20, 2010, 05:17 PM
QVT Associates GP LLC 10% Owner Sep 14, 2010 Buy $11.47 31,469 361,081 3,723,270 Sep 16, 2010, 05:28 PM
QVT Associates GP LLC 10% Owner Sep 10, 2010 Buy $11.44 178,285 2,040,266 3,688,401 Sep 14, 2010, 08:47 PM
QVT Associates GP LLC 10% Owner Sep 13, 2010 Buy $11.50 3,400 39,100 3,691,801 Sep 14, 2010, 08:47 PM
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Buy Sale Option Exercise
Owner Relationship Date Value($)
BLICKENSTAFF KIM D Director 09/21/2016 56,355
Hirmand Mohammad Interim Chief Medical Officer 09/15/2016 78,523
Hung David President and CEO 09/15/2016 149,981
Powell Andrew Kenneth William SVP, General Counsel & Crp Sec 06/06/2016 155,763
Bierly Rick CFO (former) 05/06/2016 379,637
Bierly Rick CFO (former) 05/05/2016 238,280
Svoronos Dawn Director 03/14/2016 233,400
Hung David President and CEO 03/04/2016 208,993
Hirmand Mohammad Interim Chief Medical Officer 03/04/2016 62,685
Bierly Rick Chief Financial Officer 03/04/2016 119,920
Hung David President and CEO 02/04/2016 197,993
Machado Clarence Patrick Director 01/19/2016 252,525
Machado Clarence Patrick Director 01/19/2016 2,800,562
Lobacki Joseph M Chief Commercial Officer 01/04/2016 142,523
VERNON W ANTHONY Director 12/14/2015 610,350
Hung David President and CEO 12/03/2015 471,966
Hirmand Mohammad Interim Chief Medical Officer 12/03/2015 46,655
Machado Clarence Patrick Director 09/25/2015 337,766
Machado Clarence Patrick Director 09/25/2015 3,049,106
Svoronos Dawn Director 09/08/2015 276,365
Machado Clarence Patrick Director 06/04/2015 337,860
Machado Clarence Patrick Director 06/04/2015 4,227,478
Bierly Rick Chief Financial Officer 05/20/2015 130,000
Bierly Rick Chief Financial Officer 05/08/2015 48,125
Bierly Rick Chief Financial Officer 05/04/2015 270,603
Bierly Rick Chief Financial Officer 05/05/2015 201,875
Bierly Rick Chief Financial Officer 04/15/2015 174,300
Bierly Rick Chief Financial Officer 04/15/2015 396,600
Rhodes Jennifer J GC & Corporate Secretary 03/16/2015 181,979
Svoronos Dawn Director 03/02/2015 401,163
Rhodes Jennifer J GC & Corporate Secretary 03/02/2015 94,960
Rhodes Jennifer J GC & Corporate Secretary 03/02/2015 244,000
Hung David President and CEO 03/02/2015 12,190,608
FALBERG KATHRYN E Director 02/27/2015 2,941,684
Rhodes Jennifer J GC & Corporate Secretary 02/26/2015 94,960
Rhodes Jennifer J GC & Corporate Secretary 02/26/2015 368,502
Hung David President and CEO 02/26/2015 2,295,373
Machado Clarence Patrick Director 02/10/2015 337,860
Machado Clarence Patrick Director 02/10/2015 3,739,984
Hung David President and CEO 02/04/2015 320,518
Rhodes Jennifer J GC & Corporate Secretary 02/04/2015 61,518
Machado Clarence Patrick Director 01/27/2015 346,613
Machado Clarence Patrick Director 01/27/2015 3,791,392
Hung David President and CEO 01/20/2015 10,814,241
Seely Lynn Chief Medical Officer 12/19/2014 318,949
Rhodes Jennifer J GC & Corporate Secretary 12/03/2014 102,830
Machado Clarence Patrick Director 12/03/2014 178,540
Hung David President and CEO 12/03/2014 612,460
Seely Lynn Chief Medical Officer 10/22/2014 52,925
Seely Lynn Chief Medical Officer 10/22/2014 495,141
Seely Lynn Chief Medical Officer 10/16/2014 52,925
Seely Lynn Chief Medical Officer 10/15/2014 194,737
Seely Lynn Chief Medical Officer 10/16/2014 469,850
Seely Lynn Chief Medical Officer 10/15/2014 2,169,363
Seely Lynn Chief Medical Officer 09/18/2014 264,625
Seely Lynn Chief Medical Officer 09/17/2014 253,800
Seely Lynn Chief Medical Officer 09/18/2014 2,495,158
Seely Lynn Chief Medical Officer 09/17/2014 2,920,727
Seely Lynn Chief Medical Officer 09/09/2014 211,700
Seely Lynn Chief Medical Officer 09/09/2014 1,892,016
Seely Lynn Chief Medical Officer 08/26/2014 60,335
Seely Lynn Chief Medical Officer 08/27/2014 151,366
Seely Lynn Chief Medical Officer 08/26/2014 507,032
Seely Lynn Chief Medical Officer 08/27/2014 1,281,423
Seely Lynn Chief Medical Officer 08/13/2014 167,825
Seely Lynn Chief Medical Officer 08/13/2014 1,672,456
Seely Lynn Chief Medical Officer 08/12/2014 117,313
Seely Lynn Chief Medical Officer 08/08/2014 122,005
Seely Lynn Chief Medical Officer 08/12/2014 1,050,125
Seely Lynn Chief Medical Officer 08/08/2014 1,066,821
Seely Lynn Chief Medical Officer 07/22/2014 50,513
Seely Lynn Chief Medical Officer 07/22/2014 554,710
Seely Lynn Chief Medical Officer 07/02/2014 112,620
Seely Lynn Chief Medical Officer 07/02/2014 948,194
Seely Lynn Chief Medical Officer 06/03/2014 50,513
Seely Lynn Chief Medical Officer 06/18/2014 50,513
Seely Lynn Chief Medical Officer 06/03/2014 558,760
Seely Lynn Chief Medical Officer 06/18/2014 562,530
Machado Clarence Patrick Chief Business Officer and CFO 02/18/2014 423,400
Machado Clarence Patrick Chief Business Officer and CFO 02/18/2014 3,311,646
Machado Clarence Patrick Chief Business Officer and CFO 02/11/2014 423,400
Machado Clarence Patrick Chief Business Officer and CFO 02/11/2014 3,233,121
Machado Clarence Patrick Chief Business Officer and CFO 02/05/2014 423,400
Machado Clarence Patrick Chief Business Officer and CFO 02/05/2014 2,938,574
Machado Clarence Patrick Chief Business Officer and CFO 01/28/2014 423,400
Machado Clarence Patrick Chief Business Officer and CFO 01/28/2014 3,017,122
Hung David President and CEO 01/27/2014 882,000
Hung David President and CEO 01/27/2014 11,025,357
Machado Clarence Patrick Chief Business Officer and CFO 01/21/2014 423,400
Machado Clarence Patrick Chief Business Officer and CFO 01/21/2014 3,051,627
Rhodes Jennifer J GC & Chief Compliance Officer 01/21/2014 664,720
Rhodes Jennifer J GC & Chief Compliance Officer 01/21/2014 1,067,949
Machado Clarence Patrick Chief Business Officer and CFO 12/03/2013 339,910
Hung David President and CEO 12/03/2013 942,288
BLICKENSTAFF KIM D Director 11/21/2013 336,150
BLICKENSTAFF KIM D Director 11/21/2013 1,835,100
BLICKENSTAFF KIM D Director 11/18/2013 208,950
BLICKENSTAFF KIM D Director 11/18/2013 1,851,703
Machado Clarence Patrick Chief Business Officer and CFO 11/07/2013 2,143
Hung David President and CEO 11/07/2013 15,196
Cohen Cheryl Chief Commercial Officer 10/24/2013 240,125
Cohen Cheryl Chief Commercial Officer 10/23/2013 240,125
Cohen Cheryl Chief Commercial Officer 10/24/2013 1,636,346
Cohen Cheryl Chief Commercial Officer 10/23/2013 1,576,245
Cohen Cheryl Chief Commercial Officer 08/02/2013 240,125
Cohen Cheryl Chief Commercial Officer 08/02/2013 1,482,820
Hung David President and CEO 07/05/2013 1,712,718
Cohen Cheryl Chief Commercial Officer 07/03/2013 240,125
Cohen Cheryl Chief Commercial Officer 07/03/2013 1,350,250
Hung David President and CEO 04/23/2013 88,825
Hung David President and CEO 04/19/2013 3,168,247
Hung David President and CEO 04/18/2013 11,000
Hung David President and CEO 04/22/2013 541,156
Hung David President and CEO 04/11/2013 2,631,030
Hung David President and CEO 04/05/2013 2,508,500
VERNON W ANTHONY Director 03/15/2013 490,200
VERNON W ANTHONY Director 03/15/2013 2,754,600
BLICKENSTAFF KIM D Director 03/07/2013 562,500
BLICKENSTAFF KIM D Director 03/08/2013 2,114,976
BLICKENSTAFF KIM D Director 03/07/2013 701,936
Machado Clarence Patrick Chief Business Officer and CFO 12/10/2012 278,825
Hung David President and CEO 12/10/2012 557,553
Bailey Gregory Director 10/30/2012 1,384,869
Bailey Gregory Director 10/24/2012 900,480
Bailey Gregory Director 10/16/2012 171,200
Bailey Gregory Director 10/05/2012 1,168,400
Bailey Gregory Director 10/04/2012 1,155,400
Hung David President and CEO 10/04/2012 2,895,780
Bailey Gregory Director 10/02/2012 1,691,717
Machado Clarence Patrick Chief Business Officer and CFO 10/03/2012 34,374
Machado Clarence Patrick Chief Business Officer and CFO 10/02/2012 60,490
Machado Clarence Patrick Chief Business Officer and CFO 10/01/2012 32,340
Machado Clarence Patrick Chief Business Officer and CFO 10/02/2012 536,508
Machado Clarence Patrick Chief Business Officer and CFO 10/01/2012 313,739
Machado Clarence Patrick Chief Business Officer and CFO 10/03/2012 260,483
Hung David President and CEO 09/28/2012 997,789
Cohen Cheryl Chief Commercial Officer 09/28/2012 245,742
Machado Clarence Patrick Chief Business Officer and CFO 09/28/2012 364,754
Machado Clarence Patrick Chief Business Officer and CFO 09/28/2012 364,754
Cohen Cheryl Chief Commercial Officer 09/28/2012 245,742
Hung David President and CEO 09/28/2012 997,789
Bailey Gregory Director 09/27/2012 2,810,200
Bailey Gregory Director 09/25/2012 547,800
Adams Daniel Director 09/25/2012 34,850
Adams Daniel Director 09/27/2012 723,375
Adams Daniel Director 09/25/2012 275,009
Adams Daniel Director 09/27/2012 4,627,749
Machado Clarence Patrick Chief Business Officer and CFO 09/07/2012 235,200
Machado Clarence Patrick Chief Business Officer and CFO 09/07/2012 2,114,858
Bailey Gregory Director 09/06/2012 3,096,402
Bailey Gregory Director 09/07/2012 167,433
Hung David President and CEO 09/04/2012 2,779,009
Seely Lynn Chief Medical Officer 07/25/2012 82,944
Seely Lynn Chief Medical Officer 07/26/2012 1,299,456
Seely Lynn Chief Medical Officer 07/26/2012 3,749,815
Seely Lynn Chief Medical Officer 07/25/2012 235,218
Hung David President and CEO 07/03/2012 2,376,205
Machado Clarence Patrick Chief Business Officer and CFO 07/02/2012 117,600
Machado Clarence Patrick Chief Business Officer and CFO 07/02/2012 941,100
Bailey Gregory Director 07/03/2012 190,340
Bailey Gregory Director 07/02/2012 513,700
Bailey Gregory Director 06/29/2012 988,525
VERNON W ANTHONY Director 06/14/2012 192,267
VERNON W ANTHONY Director 06/13/2012 122,820
VERNON W ANTHONY Director 06/15/2012 138,368
VERNON W ANTHONY Director 06/13/2012 2,338,249
VERNON W ANTHONY Director 06/15/2012 2,564,019
VERNON W ANTHONY Director 06/14/2012 3,566,131
Adams Daniel Director 06/14/2012 142,875
Adams Daniel Director 06/13/2012 151,281
Adams Daniel Director 06/15/2012 91,500
Adams Daniel Director 06/13/2012 2,329,418
Adams Daniel Director 06/15/2012 2,007,632
Adams Daniel Director 06/14/2012 3,142,584
BLICKENSTAFF KIM D Director 06/13/2012 66,375
BLICKENSTAFF KIM D Director 06/14/2012 90,750
BLICKENSTAFF KIM D Director 06/13/2012 1,500,174
BLICKENSTAFF KIM D Director 06/14/2012 1,991,660
Machado Clarence Patrick Chief Business Officer and CFO 05/22/2012 7,056
Machado Clarence Patrick Chief Business Officer and CFO 05/24/2012 110,544
Machado Clarence Patrick Chief Business Officer and CFO 05/22/2012 53,496
Machado Clarence Patrick Chief Business Officer and CFO 05/24/2012 838,213
Seely Lynn Chief Medical Officer 05/22/2012 168,375
Seely Lynn Chief Medical Officer 05/22/2012 1,106,334
Seely Lynn Chief Medical Officer 05/17/2012 304,001
Seely Lynn Chief Medical Officer 05/17/2012 1,263,829
Seely Lynn Chief Medical Officer 05/14/2012 754,499
Seely Lynn Chief Medical Officer 05/14/2012 3,139,029
Hung David President and CEO 05/14/2012 2,146,435
Machado Clarence Patrick Chief Business Officer and CFO 05/14/2012 117,600
Machado Clarence Patrick Chief Business Officer and CFO 05/14/2012 843,100
Machado Clarence Patrick Chief Business Officer and CFO 04/27/2012 117,600
Machado Clarence Patrick Chief Business Officer and CFO 04/27/2012 801,630
Seely Lynn Chief Medical Officer 03/08/2012 2,920,314
Seely Lynn Chief Medical Officer 03/08/2012 988,400
Seely Lynn Chief Medical Officer 03/08/2012 5,016,647
Machado Clarence Patrick Chief Business Officer and CFO 03/08/2012 117,600
Machado Clarence Patrick Chief Business Officer and CFO 03/08/2012 751,000
Hung David President and CEO 02/07/2012 3,115,795
Hung David President and CEO 02/08/2012 3,903,693
BLICKENSTAFF KIM D Director 02/08/2012 23,625
BLICKENSTAFF KIM D Director 02/07/2012 51,375
BLICKENSTAFF KIM D Director 02/08/2012 435,926
BLICKENSTAFF KIM D Director 02/07/2012 981,201
Machado Clarence Patrick Chief Business Officer and CFO 02/08/2012 225,710
Machado Clarence Patrick Chief Business Officer and CFO 02/07/2012 192,758
Machado Clarence Patrick Chief Business Officer and CFO 02/08/2012 3,942,916
Machado Clarence Patrick Chief Business Officer and CFO 02/07/2012 3,075,416
Bailey Gregory Director 11/09/2011 122,399
QVT Associates GP LLC 10% Owner 06/07/2011 8,329,089
QVT Associates GP LLC 10% Owner 06/06/2011 2,838,789
QVT Associates GP LLC 10% Owner 06/03/2011 2,045,355
QVT Associates GP LLC 10% Owner 06/02/2011 1,158,930
Machado Clarence Patrick Chief Business Officer and CFO 06/01/2011 681,030
PALEKAR ROHAN Chief Commercial Officer 04/20/2011 196,375
PALEKAR ROHAN Chief Commercial Officer 04/20/2011 282,825
PALEKAR ROHAN Chief Commercial Officer 03/21/2011 120,375
Seely Lynn Chief Medical Officer 03/15/2011 180,000
Seely Lynn Chief Medical Officer 03/15/2011 823,885
Hung David President and CEO 02/23/2011 848,150
Hung David President and CEO 02/22/2011 1,719,990
Hung David President and CEO 02/24/2011 820,430
Seely Lynn Chief Medical Officer 02/15/2011 180,000
Seely Lynn Chief Medical Officer 02/15/2011 898,320
Machado Clarence Patrick Chief Business Officer and CFO 02/09/2011 43,530
Machado Clarence Patrick Chief Business Officer and CFO 02/10/2011 238,819
Machado Clarence Patrick Chief Business Officer and CFO 02/07/2011 65,130
Seely Lynn Chief Medical Officer 01/19/2011 90,000
Seely Lynn Chief Medical Officer 01/18/2011 90,000
Seely Lynn Chief Medical Officer 01/19/2011 361,212
Seely Lynn Chief Medical Officer 01/18/2011 389,740
QVT Associates GP LLC 10% Owner 11/29/2010 2,200
QVT Associates GP LLC 10% Owner 11/23/2010 23,079
QVT Associates GP LLC 10% Owner 11/17/2010 4,400
QVT Associates GP LLC 10% Owner 10/27/2010 170,169
QVT Associates GP LLC 10% Owner 10/26/2010 468,056
QVT Associates GP LLC 10% Owner 10/22/2010 1,516,796
QVT Associates GP LLC 10% Owner 10/25/2010 256,349
QVT Associates GP LLC 10% Owner 09/17/2010 101,376
QVT Associates GP LLC 10% Owner 09/16/2010 239,242
QVT Associates GP LLC 10% Owner 09/14/2010 361,081
QVT Associates GP LLC 10% Owner 09/10/2010 2,040,266
QVT Associates GP LLC 10% Owner 09/13/2010 39,100
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