Ligand Pharmaceuticals, Inc.. (LGND) NASDAQ

$72.53 0.06 (0.08%)

Market Cap: $1.28B

As of 04/22/24 12:00 PM EDT. Market open.

(LGND)

Ligand Pharmaceuticals, Inc.. (LGND)
NASDAQ

$72.53
0.06 (0.08%)

Market Cap: $1.28B

As of 04/22/24 12:00 PM EDT. Market open.

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ligand, a pharmaceutical company, is assembling a large and diverse portfolio of current and near-term commercial revenue generating assets to assist the long-term financial growth of the company. we operate this business on a lean cost structure that allows us to maximize cash flow and ultimately deliver a meaningful return for our ... read more

COMPANY PROFILE
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
John Higgins
Full Time Employees
130
CEO Compensation (Base)
$627,413
CEO Compensation (Total)
$6.31M
URL
Address
3911 Sorrento Valley Blvd Ste 110, California, San Diego, 92121-1402.
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
John Higgins
Full Time Employees
130
CEO Compensation (Base)
$627,413
CEO Compensation (Total)
$6.31M
Address
3911 Sorrento Valley Blvd Ste 110, California, San Diego, 92121-1402.
PRICE CHART FOR LIGAND PHARMACEUTICALS, INC.
1w
1m
3m
6m
YTD
1y
5y
MAX
From: To:
NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
$73.35
Previous Close
$72.47
Days Range
$71.23 - $72.95
52 week range
$49.24 - $94.57
Volume
8,997
Avg. Volume (30 days)
157,952
Market Cap
$1.28B
Dividend Yield
-
P/E
24.60
Shares Outstanding
17,705,287
Open
$73.35
Previous Close
$72.47
Days Range
$71.23 - $72.95
52 week range
$49.24 - $94.57
Volume
8,997
Avg. Volume (30 days)
157,952
Market Cap
$1.28B
Dividend Yield
-
P/E
24.60
Shares Outstanding
17,705,287
FINANCIAL STATEMENTS FOR LIGAND PHARMACEUTICALS, INC.
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INSIDER TRANSACTIONS FOR LIGAND PHARMACEUTICALS, INC.
OwnerRelationshipDateTransactionCost# SharesValue($)Total SharesForm 4
Davis Todd CChief Executive OfficerMar 25, 2024 Option Exercise$57.3916,015919,147120,160Mar 27, 2024, 05:47 PM
Sabba Stephen LDirectorMar 05, 2024 Sale$74.301,893140,65028,926Mar 07, 2024, 01:27 PM
Aryeh JasonDirectorMar 05, 2024 Option Exercise$39.352,893113,84074,422Mar 06, 2024, 05:28 PM
Espinoza OctavioChief Financial OfficerFeb 28, 2024 Option Exercise$56.621,26471,56429,895Feb 29, 2024, 06:50 PM
Espinoza OctavioChief Financial OfficerFeb 28, 2024 Sale$88.4614012,38429,755Feb 29, 2024, 06:50 PM
Reardon AndrewCHIEF LEGAL OFFICER &Feb 15, 2024 Option Exercise$74.6559344,26714,997Feb 16, 2024, 08:10 PM
Korenberg Matthew EPRESIDENT & CHIEF OPERATINGFeb 15, 2024 Option Exercise$74.654,778356,67889,445Feb 16, 2024, 08:10 PM
Espinoza OctavioChief Financial OfficerFeb 15, 2024 Option Exercise$74.651,479110,40721,423Feb 16, 2024, 08:10 PM
Davis Todd CCHIEF EXECUTIVE OFFICERFeb 15, 2024 Option Exercise$74.651,381103,09271,709Feb 16, 2024, 08:10 PM
Korenberg Matthew EPRESIDENT & CHIEF OPERATINGJan 02, 2024 Option Exercise$72.312,917210,92894,223Jan 04, 2024, 04:07 PM
Reardon AndrewCHIEF LEGAL OFFICER &Dec 29, 2023 Option Exercise$60.7117910,86715,590Jan 04, 2024, 04:07 PM
Espinoza OctavioChief Financial OfficerDec 05, 2023 Option Exercise$59.611,26975,64522,902Dec 06, 2023, 03:27 PM
Korenberg Matthew EPRESIDENT & CHIEF OPERATINGDec 05, 2023 Option Exercise$59.611,984118,26697,140Dec 06, 2023, 03:27 PM
Espinoza OctavioChief Financial OfficerOct 01, 2023 Option Exercise$59.9234620,73224,171Oct 03, 2023, 04:36 PM
Davis Todd CCHIEF EXECUTIVE OFFICERSep 22, 2023 Buy$59.384,000237,52973,090Sep 25, 2023, 04:44 PM
Reardon AndrewCHIEF LEGAL OFFICER &Aug 10, 2023 Option Exercise$68.7389761,65115,411Aug 14, 2023, 04:20 PM
Korenberg Matthew EPRESIDENT & CHIEF OPERATINGJun 30, 2023 Option Exercise$56.7837621,34999,124Jul 10, 2023, 06:42 PM
Espinoza OctavioChief Financial OfficerJun 30, 2023 Option Exercise$56.7837521,29224,517Jul 10, 2023, 06:42 PM
Davis Todd CCHIEF EXECUTIVE OFFICERJun 09, 2023 Option Exercise$73.7642030,97969,090Jun 13, 2023, 06:52 PM
KOZARICH JOHN WDirectorMay 16, 2023 Sale$77.204,444343,08138,488May 18, 2023, 05:18 PM
Sabba Stephen LDirectorMay 10, 2023 Sale$77.136,408494,22525,784May 12, 2023, 03:43 PM
KOZARICH JOHN WDirectorMay 08, 2023 Option Exercise$18.826,408120,59948,621May 10, 2023, 07:15 PM
KOZARICH JOHN WDirectorMay 08, 2023 Sale$76.566,408490,62842,802May 10, 2023, 07:15 PM
Reardon AndrewSee RemarksMar 24, 2023 Sale$69.9230020,97716,308Mar 28, 2023, 05:00 PM
Korenberg Matthew EPresident & COOFeb 15, 2023 Option Exercise$72.982,890210,91289,679Feb 17, 2023, 07:23 PM
Espinoza OctavioChief Financial OfficerFeb 15, 2023 Option Exercise$72.9884961,96018,096Feb 17, 2023, 07:20 PM
Espinoza OctavioChief Financial OfficerDec 30, 2022 Option Exercise$56.7827515,61418,945Jan 04, 2023, 05:00 PM
Korenberg Matthew EPresident & COODec 28, 2022 Option Exercise$66.293,859255,81392,569Dec 30, 2022, 05:00 PM
HIGGINS JOHN LDirectorDec 28, 2022 Option Exercise$66.295,289350,608417,695Dec 30, 2022, 05:00 PM
HIGGINS JOHN LDirectorDec 16, 2022 Sale$61.8710,000618,657422,984Dec 20, 2022, 06:36 PM
HIGGINS JOHN LDirectorDec 12, 2022 Option Exercise$64.803,944255,571432,984Dec 14, 2022, 05:00 PM
HIGGINS JOHN LDirectorDec 12, 2022 Option Exercise$12.7820,000255,600436,928Dec 14, 2022, 05:00 PM
Korenberg Matthew EPresident & COONov 30, 2022 Option Exercise$72.903,593261,93082,428Dec 01, 2022, 09:42 PM
HIGGINS JOHN LChief Executive OfficerNov 30, 2022 Option Exercise$72.909,803714,639416,928Dec 01, 2022, 09:42 PM
Espinoza OctavioChief Financial OfficerNov 30, 2022 Option Exercise$72.901,18786,5327,670Dec 01, 2022, 09:41 PM
Reardon AndrewSee RemarksNov 30, 2022 Option Exercise$72.901,07378,22210,940Dec 01, 2022, 09:39 PM
HIGGINS JOHN LChief Executive OfficerNov 18, 2022 Option Exercise$12.7810,000127,800426,731Nov 21, 2022, 07:04 PM
HIGGINS JOHN LChief Executive OfficerNov 17, 2022 Sale$78.3210,000783,173416,731Nov 21, 2022, 07:04 PM
Espinoza OctavioChief Financial OfficerNov 09, 2022 Sale$75.641,696128,2838,857Nov 10, 2022, 04:30 PM
HIGGINS JOHN LChief Executive OfficerSep 16, 2022 Sale$88.061,00088,060366,180Sep 22, 2022, 08:32 PM
HIGGINS JOHN LChief Executive OfficerSep 15, 2022 Sale$90.002,000180,000367,180Sep 16, 2022, 07:49 PM
HIGGINS JOHN LChief Executive OfficerSep 16, 2022 Sale$89.353,000268,050364,180Sep 16, 2022, 07:49 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOJun 30, 2022 Option Exercise$75.8416412,43752,532Jul 06, 2022, 08:00 PM
HIGGINS JOHN LChief Executive OfficerJun 30, 2022 Option Exercise$75.8416412,437369,180Jul 06, 2022, 08:00 PM
FOEHR MATTHEW WPresident and COOMay 13, 2022 Buy$82.762,500206,910173,354May 13, 2022, 07:05 PM
HIGGINS JOHN LChief Executive OfficerMay 09, 2022 Option Exercise$21.928,000175,360348,593May 10, 2022, 05:33 PM
FOEHR MATTHEW WPresident and COOFeb 15, 2022 Option Exercise$123.683,546438,569173,166Feb 16, 2022, 08:24 PM
HIGGINS JOHN LChief Executive OfficerFeb 15, 2022 Option Exercise$123.685,923732,557344,570Feb 16, 2022, 08:23 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOFeb 15, 2022 Option Exercise$123.683,407421,37846,807Feb 16, 2022, 08:23 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOJan 26, 2022 Option Exercise$113.683,628412,43150,022Jan 28, 2022, 08:43 PM
HIGGINS JOHN LChief Executive OfficerJan 26, 2022 Option Exercise$113.689,2431,050,744355,201Jan 28, 2022, 08:42 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryJan 26, 2022 Option Exercise$113.682,156245,09433,298Jan 28, 2022, 08:42 PM
FOEHR MATTHEW WPresident and COOJan 26, 2022 Option Exercise$113.685,125582,610177,588Jan 28, 2022, 08:41 PM
LAMATTINA JOHN LDirectorNov 16, 2021 Option Exercise$32.304,835156,17030,233Nov 17, 2021, 05:06 PM
LAMATTINA JOHN LDirectorNov 16, 2021 Sale$161.864,835782,57925,398Nov 17, 2021, 05:06 PM
HIGGINS JOHN LChief Executive OfficerNov 12, 2021 Sale$160.503,000481,500335,095Nov 12, 2021, 07:31 PM
FOEHR MATTHEW WPresident and COONov 11, 2021 Option Exercise$28.5412,188347,818177,685Nov 12, 2021, 04:54 PM
FOEHR MATTHEW WPresident and COONov 11, 2021 Sale$163.0211,1601,819,259166,525Nov 12, 2021, 04:54 PM
FOEHR MATTHEW WPresident and COOAug 04, 2021 Option Exercise$29.239,982291,745173,195Aug 05, 2021, 04:44 PM
FOEHR MATTHEW WPresident and COOAug 04, 2021 Sale$109.678,840969,509164,355Aug 05, 2021, 04:44 PM
HIGGINS JOHN LChief Executive OfficerJun 30, 2021 Option Exercise$85.9124721,220338,095Jul 02, 2021, 05:14 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOJun 30, 2021 Option Exercise$85.9124721,22039,690Jul 02, 2021, 05:13 PM
KOZARICH JOHN WDirectorMay 11, 2021 Option Exercise$128.5639150,26734,152May 13, 2021, 08:57 PM
KOZARICH JOHN WDirectorMay 11, 2021 Option Exercise$10.124,83548,93034,543May 13, 2021, 08:57 PM
KOZARICH JOHN WDirectorFeb 22, 2021 Option Exercise$10.122,50025,30029,708Feb 23, 2021, 05:18 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryFeb 15, 2021 Option Exercise$172.461,015175,04728,701Feb 18, 2021, 06:28 PM
FOEHR MATTHEW WPresident and COOFeb 15, 2021 Option Exercise$172.463,098534,281167,557Feb 18, 2021, 06:28 PM
HIGGINS JOHN LChief Executive OfficerFeb 15, 2021 Option Exercise$172.465,212898,862341,856Feb 18, 2021, 06:27 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOFeb 15, 2021 Option Exercise$172.462,309398,21041,318Feb 18, 2021, 06:27 PM
Davis Todd CDirectorFeb 11, 2021 Option Exercise$195.912,474484,68150,152Feb 12, 2021, 06:23 PM
Davis Todd CDirectorFeb 10, 2021 Sale$213.145,0831,083,41147,678Feb 12, 2021, 06:23 PM
Sabba Stephen LDirectorFeb 09, 2021 Option Exercise$11.3214,670166,13839,101Feb 11, 2021, 04:06 PM
Sabba Stephen LDirectorFeb 09, 2021 Sale$208.5314,6703,059,12338,545Feb 11, 2021, 04:06 PM
HIGGINS JOHN LChief Executive OfficerFeb 05, 2021 Option Exercise$203.032,970602,999343,060Feb 09, 2021, 06:08 PM
HIGGINS JOHN LChief Executive OfficerFeb 05, 2021 Option Exercise$12.16114,6661,394,017346,030Feb 09, 2021, 06:08 PM
HIGGINS JOHN LChief Executive OfficerFeb 05, 2021 Sale$203.4054,66611,119,228286,030Feb 09, 2021, 06:08 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryFeb 04, 2021 Sale$178.5018,0973,230,36928,906Feb 05, 2021, 05:03 PM
FOEHR MATTHEW WPresident and COOFeb 04, 2021 Option Exercise$23.0745,5471,050,890212,745Feb 05, 2021, 05:03 PM
FOEHR MATTHEW WPresident and COOFeb 04, 2021 Sale$176.8644,5477,878,582168,198Feb 05, 2021, 05:03 PM
HIGGINS JOHN LChief Executive OfficerJan 25, 2021 Option Exercise$156.017,4411,160,870243,422Jan 27, 2021, 07:04 PM
HIGGINS JOHN LChief Executive OfficerJan 27, 2021 Option Exercise$17.6670,0001,236,400283,422Jan 27, 2021, 07:04 PM
HIGGINS JOHN LChief Executive OfficerJan 25, 2021 Option Exercise$14.4750,000723,500285,310Jan 27, 2021, 07:04 PM
HIGGINS JOHN LChief Executive OfficerJan 25, 2021 Sale$159.0050,0007,950,000235,310Jan 27, 2021, 07:04 PM
HIGGINS JOHN LChief Executive OfficerJan 27, 2021 Sale$182.0040,0007,280,000243,422Jan 27, 2021, 07:04 PM
FOEHR MATTHEW WPresident and COOJan 25, 2021 Option Exercise$156.013,325518,733160,603Jan 27, 2021, 07:03 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOJan 25, 2021 Option Exercise$156.012,111329,33730,933Jan 27, 2021, 07:03 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryJan 25, 2021 Option Exercise$156.041,339208,94343,512Jan 27, 2021, 07:02 PM
Davis Todd CDirectorJan 27, 2021 Option Exercise$113.502,456278,75652,761Jan 27, 2021, 07:02 PM
HIGGINS JOHN LChief Executive OfficerDec 31, 2020 Option Exercise$84.5322318,851235,310Jan 05, 2021, 08:30 PM
HIGGINS JOHN LChief Executive OfficerDec 08, 2020 Option Exercise$87.521,683147,296235,087Dec 09, 2020, 06:12 PM
HIGGINS JOHN LChief Executive OfficerDec 08, 2020 Option Exercise$10.0514,657147,303236,770Dec 09, 2020, 06:12 PM
HIGGINS JOHN LChief Executive OfficerNov 09, 2020 Option Exercise$81.772,458200,991222,113Nov 10, 2020, 07:41 PM
HIGGINS JOHN LChief Executive OfficerNov 09, 2020 Option Exercise$10.0520,000201,000224,571Nov 10, 2020, 07:41 PM
Patel SunilDirectorNov 02, 2020 Buy$82.521,00082,52028,190Nov 04, 2020, 04:19 PM
FOEHR MATTHEW WPresident and COOAug 24, 2020 Option Exercise$21.92781,710155,491Aug 25, 2020, 07:10 PM
FOEHR MATTHEW WPresident and COOAug 21, 2020 Option Exercise$20.388,015163,338162,638Aug 25, 2020, 07:10 PM
FOEHR MATTHEW WPresident and COOAug 24, 2020 Sale$110.89788,649155,413Aug 25, 2020, 07:10 PM
FOEHR MATTHEW WPresident and COOAug 21, 2020 Sale$112.887,225815,544155,413Aug 25, 2020, 07:10 PM
HIGGINS JOHN LChief Executive OfficerJul 07, 2020 Option Exercise$70.014,315302,098204,571Jul 09, 2020, 04:28 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryJun 30, 2020 Option Exercise$89.0323821,18941,115Jul 01, 2020, 08:06 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOJun 30, 2020 Option Exercise$89.0323821,18925,936Jul 01, 2020, 08:05 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryJun 04, 2020 Sale$118.5911,1461,321,77140,877Jun 05, 2020, 04:07 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOFeb 15, 2019 Option Exercise$120.861,166140,92316,115Apr 24, 2020, 07:24 PM
FOEHR MATTHEW WPresident and COOFeb 15, 2019 Option Exercise$120.862,826341,550124,615Apr 24, 2020, 07:23 PM
HIGGINS JOHN LChief Executive OfficerFeb 15, 2019 Option Exercise$120.864,917594,269136,981Apr 24, 2020, 07:22 PM
FOEHR MATTHEW WPresident and COOMar 13, 2020 Option Exercise$21.922,00043,840157,449Mar 13, 2020, 06:33 PM
FOEHR MATTHEW WPresident and COOFeb 27, 2020 Option Exercise$15.898,931141,941160,968Feb 27, 2020, 08:35 PM
FOEHR MATTHEW WPresident and COOFeb 27, 2020 Sale$110.007,225794,750153,743Feb 27, 2020, 08:35 PM
HIGGINS JOHN LChief Executive OfficerFeb 15, 2020 Option Exercise$97.235,116497,429208,600Feb 18, 2020, 05:11 PM
HIGGINS JOHN LChief Executive OfficerFeb 13, 2020 Option Exercise$95.685,009479,261196,730Feb 18, 2020, 05:11 PM
HIGGINS JOHN LChief Executive OfficerFeb 13, 2020 Option Exercise$9.9648,125479,325201,739Feb 18, 2020, 05:11 PM
FOEHR MATTHEW WPresident and COOFeb 15, 2020 Option Exercise$97.232,486241,714155,360Feb 18, 2020, 05:09 PM
FOEHR MATTHEW WPresident and COOFeb 14, 2020 Option Exercise$14.477,225104,546163,454Feb 18, 2020, 05:09 PM
FOEHR MATTHEW WPresident and COOFeb 13, 2020 Option Exercise$21.9249610,872148,833Feb 18, 2020, 05:09 PM
FOEHR MATTHEW WPresident and COOFeb 14, 2020 Sale$95.847,225692,467156,229Feb 18, 2020, 05:09 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryFeb 15, 2020 Option Exercise$97.2388185,66052,597Feb 18, 2020, 05:07 PM
Korenberg Matthew EEVP,Finance & Strategy and CFODec 20, 2019 Option Exercise$105.872,114223,80920,016Dec 26, 2019, 02:01 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryDec 20, 2019 Option Exercise$105.871,131119,73949,069Dec 26, 2019, 02:01 PM
FOEHR MATTHEW WPresident and COODec 20, 2019 Option Exercise$105.873,654386,849148,337Dec 26, 2019, 02:01 PM
HIGGINS JOHN LChief Executive OfficerDec 20, 2019 Option Exercise$105.876,749714,517153,614Dec 26, 2019, 02:00 PM
FOEHR MATTHEW WPresident and COONov 12, 2019 Option Exercise$21.921,00121,942144,620Nov 13, 2019, 04:07 PM
FOEHR MATTHEW WPresident and COOSep 05, 2019 Option Exercise$21.921,00522,030143,619Sep 05, 2019, 07:24 PM
Aryeh JasonDirectorSep 03, 2019 Buy$87.0175065,25867,203Sep 04, 2019, 07:30 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOSep 03, 2019 Buy$86.1850043,09117,151Sep 03, 2019, 07:34 PM
FOEHR MATTHEW WPresident and COOAug 12, 2019 Option Exercise$21.921,16325,493142,614Aug 13, 2019, 01:45 PM
Aryeh JasonDirectorAug 05, 2019 Buy$90.0174667,14666,453Aug 06, 2019, 05:18 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryAug 05, 2019 Option Exercise$67.721,09374,01347,172Aug 06, 2019, 05:17 PM
Davis Todd CDirectorAug 02, 2019 Buy$93.591,00093,59449,474Aug 05, 2019, 07:04 PM
LAMATTINA JOHN LDirectorAug 01, 2019 Option Exercise$95.5884780,95823,937Aug 05, 2019, 07:00 PM
LAMATTINA JOHN LDirectorAug 01, 2019 Option Exercise$32.302,50080,75024,784Aug 05, 2019, 07:00 PM
Patel SunilDirectorAug 02, 2019 Buy$95.981,00095,98026,359Aug 05, 2019, 06:56 PM
Sabba Stephen LDirectorJul 31, 2019 Sale$94.454,091386,39523,600Aug 01, 2019, 02:49 PM
HIGGINS JOHN LChief Executive OfficerJul 31, 2019 Buy$95.451,850176,582146,749Jul 31, 2019, 07:26 PM
Aryeh JasonDirectorJul 31, 2019 Buy$93.0075470,12265,707Jul 31, 2019, 06:50 PM
Aryeh JasonDirectorJul 30, 2019 Buy$100.223,000300,66364,953Jul 31, 2019, 06:50 PM
Aryeh JasonDirectorJul 29, 2019 Buy$106.0125026,50361,953Jul 31, 2019, 06:50 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryJun 28, 2019 Option Exercise$97.0318217,65946,079Jul 02, 2019, 09:50 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOJun 28, 2019 Option Exercise$97.0318217,65916,651Jul 02, 2019, 09:49 PM
Aryeh JasonDirectorJun 11, 2019 Buy$107.0125026,75361,703Jun 12, 2019, 06:51 PM
FOEHR MATTHEW WPresident and COOJun 11, 2019 Option Exercise$21.921,00422,008141,451Jun 12, 2019, 06:50 PM
HIGGINS JOHN LChief Executive OfficerMay 31, 2019 Buy$108.201,000108,202144,899May 31, 2019, 07:29 PM
Aryeh JasonDirectorMay 31, 2019 Buy$108.5150054,25560,618May 31, 2019, 06:27 PM
Aryeh JasonDirectorMay 30, 2019 Buy$110.0125027,50360,118May 31, 2019, 06:27 PM
Aryeh JasonDirectorMay 29, 2019 Buy$111.0125027,75359,868May 31, 2019, 06:27 PM
Aryeh JasonDirectorMay 20, 2019 Buy$112.0125028,00359,618May 22, 2019, 05:36 PM
Aryeh JasonDirectorMay 14, 2019 Buy$112.5125028,12859,368May 16, 2019, 03:54 PM
HIGGINS JOHN LChief Executive OfficerMay 14, 2019 Buy$113.502,500283,750143,899May 14, 2019, 07:57 PM
KOZARICH JOHN WDirectorMay 14, 2019 Option Exercise$17.882,50044,70028,042May 14, 2019, 07:56 PM
KOZARICH JOHN WDirectorMay 14, 2019 Sale$112.922,500282,30025,542May 14, 2019, 07:56 PM
FOEHR MATTHEW WPresident and COOMar 14, 2019 Option Exercise$9.9714,894148,493140,447Mar 15, 2019, 02:00 PM
Aryeh JasonDirectorMar 13, 2019 Buy$112.5120222,72751,594Mar 15, 2019, 01:59 PM
HIGGINS JOHN LChief Executive OfficerMar 13, 2019 Buy$114.292,500285,725141,399Mar 15, 2019, 01:58 PM
FOEHR MATTHEW WPresident and COOJan 23, 2019 Option Exercise$111.782,568287,051118,081Jan 25, 2019, 04:31 PM
HIGGINS JOHN LChief Executive OfficerJan 23, 2019 Option Exercise$111.786,765756,192126,090Jan 25, 2019, 04:31 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOJan 23, 2019 Option Exercise$111.781,325148,10810,065Jan 25, 2019, 04:30 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryJan 10, 2019 Option Exercise$65.622,850187,02939,913Jan 14, 2019, 09:17 AM
HIGGINS JOHN LChief Executive OfficerJan 10, 2019 Option Exercise$16.1433,790545,371119,209Jan 14, 2019, 09:16 AM
Berkman Charles SSVP, Gen. Counsel & SecretaryDec 17, 2018 Option Exercise$21.923,40074,52837,063Dec 17, 2018, 07:58 PM
FOEHR MATTHEW WPresident and COODec 12, 2018 Option Exercise$9.977,99979,750113,387Dec 12, 2018, 05:32 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryOct 24, 2018 Option Exercise$16.793,90065,46233,663Oct 25, 2018, 05:44 PM
Davis Todd CDirectorOct 12, 2018 Option Exercise$103.295,083525,02147,639Oct 15, 2018, 12:55 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryOct 11, 2018 Option Exercise$14.472,00028,94029,763Oct 12, 2018, 06:52 PM
Davis Todd CDirectorOct 08, 2018 Sale$253.992,500634,97742,556Oct 09, 2018, 04:24 PM
KOZARICH JOHN WDirectorOct 01, 2018 Sale$275.042,500687,61026,142Oct 02, 2018, 06:24 PM
FOEHR MATTHEW WPresident and COOOct 01, 2018 Option Exercise$13.8014,088194,457117,388Oct 02, 2018, 06:24 PM
FOEHR MATTHEW WPresident and COOOct 01, 2018 Sale$273.8812,0003,286,560105,388Oct 02, 2018, 06:24 PM
Berkman Charles SSVP, Gen. Counsel & SecretarySep 17, 2018 Option Exercise$100.382,813282,36930,576Sep 18, 2018, 06:16 PM
Berkman Charles SSVP, Gen. Counsel & SecretarySep 17, 2018 Sale$250.692,813705,18327,763Sep 18, 2018, 06:16 PM
Sabba Stephen LDirectorSep 04, 2018 Option Exercise$13.235,00066,15031,856Sep 06, 2018, 10:40 AM
Sabba Stephen LDirectorSep 04, 2018 Sale$255.055,0001,275,25026,856Sep 06, 2018, 10:40 AM
FOEHR MATTHEW WPresident and COOSep 04, 2018 Option Exercise$14.1113,044184,049115,300Sep 05, 2018, 08:18 PM
FOEHR MATTHEW WPresident and COOSep 04, 2018 Sale$255.0112,0003,060,084103,300Sep 05, 2018, 08:18 PM
Berkman Charles SSVP, Gen. Counsel & SecretarySep 04, 2018 Option Exercise$69.9819,4171,358,79647,180Sep 05, 2018, 08:00 PM
Berkman Charles SSVP, Gen. Counsel & SecretarySep 04, 2018 Sale$254.9919,4174,951,06327,763Sep 05, 2018, 08:00 PM
LAMATTINA JOHN LDirectorSep 04, 2018 Option Exercise$12.533,33541,78824,784Sep 05, 2018, 07:59 PM
LAMATTINA JOHN LDirectorSep 04, 2018 Sale$254.963,335850,29221,449Sep 05, 2018, 07:59 PM
HIGGINS JOHN LChief Executive OfficerAug 30, 2018 Sale$258.253,500903,87585,419Aug 31, 2018, 01:22 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOAug 29, 2018 Option Exercise$85.7911,540990,01725,099Aug 29, 2018, 08:35 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOAug 29, 2018 Sale$256.6918,3574,712,0586,742Aug 29, 2018, 08:35 PM
Aryeh JasonDirectorAug 16, 2018 Sale$245.001,080264,60078,254Aug 17, 2018, 07:38 PM
Aryeh JasonDirectorAug 17, 2018 Sale$241.8126,8626,495,55451,392Aug 17, 2018, 07:38 PM
Davis Todd CDirectorAug 17, 2018 Sale$239.503,167758,49745,056Aug 17, 2018, 07:38 PM
Davis Todd CDirectorAug 16, 2018 Sale$239.935,8331,399,50648,223Aug 17, 2018, 07:38 PM
HIGGINS JOHN LChief Executive OfficerAug 17, 2018 Option Exercise$14.4712,993188,009101,912Aug 17, 2018, 07:37 PM
HIGGINS JOHN LChief Executive OfficerAug 16, 2018 Option Exercise$14.473,00743,511110,426Aug 17, 2018, 07:37 PM
HIGGINS JOHN LChief Executive OfficerAug 17, 2018 Sale$243.0012,9933,157,29988,919Aug 17, 2018, 07:37 PM
HIGGINS JOHN LChief Executive OfficerAug 16, 2018 Sale$241.3321,5075,190,26388,919Aug 17, 2018, 07:37 PM
Patel SunilDirectorAug 16, 2018 Option Exercise$16.7027,005451,05866,811Aug 17, 2018, 07:37 PM
Patel SunilDirectorAug 16, 2018 Sale$240.0542,28710,150,82524,524Aug 17, 2018, 07:37 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOAug 06, 2018 Option Exercise$226.74836189,55513,559Aug 07, 2018, 04:35 PM
KOZARICH JOHN WDirectorJul 02, 2018 Sale$207.482,500518,70028,642Jul 03, 2018, 06:50 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOJun 29, 2018 Option Exercise$117.8418021,21014,395Jul 03, 2018, 03:27 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryJun 29, 2018 Option Exercise$117.8418021,21027,763Jul 03, 2018, 03:27 PM
LAMATTINA JOHN LDirectorJun 04, 2018 Option Exercise$12.534,00050,12024,956Jun 04, 2018, 07:01 PM
LAMATTINA JOHN LDirectorJun 04, 2018 Sale$194.514,000778,04020,956Jun 04, 2018, 07:01 PM
HIGGINS JOHN LChief Executive OfficerMay 15, 2018 Option Exercise$16.1412,405200,217119,824May 15, 2018, 06:41 PM
HIGGINS JOHN LChief Executive OfficerMay 15, 2018 Sale$179.9712,4052,232,491107,419May 15, 2018, 06:41 PM
FOEHR MATTHEW WPresident and COOMay 10, 2018 Option Exercise$13.999,936139,026110,082May 11, 2018, 05:32 PM
FOEHR MATTHEW WPresident and COOMay 10, 2018 Sale$167.638,8811,488,687101,201May 11, 2018, 05:32 PM
KOZARICH JOHN WDirectorApr 02, 2018 Sale$160.432,500401,06330,649Apr 03, 2018, 12:00 AM
Sabba Stephen LDirectorMar 12, 2018 Sale$180.73622112,41426,363Mar 13, 2018, 06:15 PM
Aryeh JasonDirectorMar 09, 2018 Sale$176.484,000705,90079,334Mar 09, 2018, 06:28 PM
Aryeh JasonDirectorMar 08, 2018 Sale$174.883,500612,09483,334Mar 09, 2018, 06:28 PM
LAMATTINA JOHN LDirectorMar 05, 2018 Option Exercise$10.123,33533,75024,291Mar 06, 2018, 06:36 PM
LAMATTINA JOHN LDirectorMar 05, 2018 Sale$160.903,335536,60520,956Mar 06, 2018, 06:36 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOMar 06, 2018 Option Exercise$165.8755091,22814,215Mar 06, 2018, 06:36 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryMar 06, 2018 Option Exercise$165.8739265,02127,583Mar 06, 2018, 06:36 PM
HIGGINS JOHN LChief Executive OfficerMar 06, 2018 Option Exercise$165.872,982494,624107,419Mar 06, 2018, 06:36 PM
FOEHR MATTHEW WPresident and COOMar 06, 2018 Option Exercise$165.871,457241,673101,201Mar 06, 2018, 06:36 PM
Aryeh JasonDirectorFeb 23, 2018 Sale$155.003,417529,63586,834Feb 27, 2018, 06:40 PM
Davis Todd CDirectorFeb 27, 2018 Sale$151.9012,3351,873,71153,563Feb 27, 2018, 06:39 PM
Davis Todd CDirectorFeb 26, 2018 Sale$153.574,835742,53565,898Feb 27, 2018, 06:39 PM
FOEHR MATTHEW WPresident and COOFeb 23, 2018 Option Exercise$13.776,44888,785101,279Feb 27, 2018, 06:39 PM
FOEHR MATTHEW WPresident and COOFeb 23, 2018 Sale$152.985,444832,82395,835Feb 27, 2018, 06:39 PM
Berkman Charles SSVP, Gen. Counsel & SecretaryFeb 15, 2018 Option Exercise$157.181,036162,83825,571Feb 16, 2018, 05:40 PM
FOEHR MATTHEW WPresident and COOFeb 15, 2018 Option Exercise$157.183,663575,75096,983Feb 16, 2018, 05:39 PM
HIGGINS JOHN LChief Executive OfficerFeb 15, 2018 Option Exercise$157.186,242981,118100,065Feb 16, 2018, 05:38 PM
HIGGINS JOHN LChief Executive OfficerFeb 15, 2018 Sale$157.039,0001,413,279102,700Feb 16, 2018, 05:38 PM
Korenberg Matthew EEVP,Finance & Strategy and CFOFeb 15, 2018 Option Exercise$157.18680106,88210,013Feb 16, 2018, 05:37 PM
HIGGINS JOHN LChief Executive OfficerJan 24, 2018 Sale$165.0022,5003,712,500111,700Jan 26, 2018, 05:31 PM
HIGGINS JOHN LChief Executive OfficerJan 19, 2018 Option Exercise$16.1416,249262,259162,299Jan 22, 2018, 07:23 PM
HIGGINS JOHN LChief Executive OfficerJan 19, 2018 Sale$153.7028,0994,318,906146,050Jan 22, 2018, 07:23 PM
KOZARICH JOHN WDirectorJan 10, 2018 Sale$145.002,500362,50033,149Jan 11, 2018, 05:55 PM
Korenberg Matthew EVP, Finance and CFODec 28, 2017 Option Exercise$138.661,530212,15010,367Dec 29, 2017, 09:17 PM
FOEHR MATTHEW WPresident and COODec 28, 2017 Option Exercise$138.662,971411,95998,494Dec 29, 2017, 09:17 PM
HIGGINS JOHN LChief Executive OfficerDec 28, 2017 Option Exercise$138.665,199720,893146,050Dec 29, 2017, 09:16 PM
Berkman Charles SVP, Gen. Counsel & SecretaryDec 28, 2017 Option Exercise$138.661,175162,92626,095Dec 29, 2017, 09:16 PM
Sabba Stephen LDirectorDec 20, 2017 Sale$137.25925126,95626,985Dec 21, 2017, 06:31 AM
Aryeh JasonDirectorNov 17, 2017 Sale$140.2224,4003,421,36890,251Nov 20, 2017, 05:01 PM
HIGGINS JOHN LChief Executive OfficerNov 17, 2017 Sale$140.342,258316,888141,284Nov 20, 2017, 05:01 PM
LAMATTINA JOHN LDirectorNov 17, 2017 Option Exercise$10.124,00040,48024,956Nov 17, 2017, 07:19 PM
LAMATTINA JOHN LDirectorNov 17, 2017 Sale$139.794,000559,16020,956Nov 17, 2017, 07:19 PM
KOZARICH JOHN WDirectorNov 16, 2017 Sale$141.715,000708,55035,649Nov 17, 2017, 05:14 PM
Korenberg Matthew EVP, Finance and CFONov 17, 2017 Sale$142.636,559935,5108,147Nov 17, 2017, 05:11 PM
HIGGINS JOHN LChief Executive OfficerNov 16, 2017 Sale$142.535,269750,991143,542Nov 17, 2017, 05:10 PM
HIGGINS JOHN LChief Executive OfficerOct 13, 2017 Option Exercise$143.041,744249,462148,811Oct 17, 2017, 05:39 PM
HIGGINS JOHN LChief Executive OfficerOct 13, 2017 Option Exercise$21.9211,384249,537150,555Oct 17, 2017, 05:39 PM
HIGGINS JOHN LChief Executive OfficerSep 05, 2017 Option Exercise$21.005,000105,000144,171Sep 06, 2017, 08:48 PM
HIGGINS JOHN LChief Executive OfficerSep 05, 2017 Sale$130.005,000650,000139,171Sep 06, 2017, 08:48 PM
Aryeh JasonDirectorAug 23, 2017 Sale$127.992,000255,980114,651Aug 25, 2017, 05:36 PM
FOEHR MATTHEW WPresident and COOAug 09, 2017 Option Exercise$9.976,95069,292101,020Aug 10, 2017, 06:40 PM
FOEHR MATTHEW WPresident and COOAug 09, 2017 Sale$127.516,100777,82394,920Aug 10, 2017, 06:40 PM
Berkman Charles SVP, Gen. Counsel & SecretaryAug 09, 2017 Sale$126.9618,6252,364,66724,423Aug 10, 2017, 06:40 PM
HIGGINS JOHN LChief Executive OfficerAug 08, 2017 Option Exercise$21.005,483115,143144,654Aug 10, 2017, 06:39 PM
HIGGINS JOHN LChief Executive OfficerAug 08, 2017 Sale$125.005,483685,375139,171Aug 10, 2017, 06:39 PM
Korenberg Matthew EVP, Finance and CFOAug 06, 2017 Option Exercise$122.0660974,33514,706Aug 08, 2017, 05:50 PM
Berkman Charles SVP, Gen. Counsel & SecretaryJun 30, 2017 Option Exercise$87.1324321,17143,048Jul 05, 2017, 06:45 PM
Korenberg Matthew EVP, Finance and CFOJun 30, 2017 Option Exercise$87.1324321,17115,315Jul 05, 2017, 06:44 PM
HIGGINS JOHN LChief Executive OfficerJun 21, 2017 Option Exercise$21.004,66697,986143,837Jun 23, 2017, 04:16 PM
HIGGINS JOHN LChief Executive OfficerJun 21, 2017 Sale$120.004,666559,920139,171Jun 23, 2017, 04:16 PM
HIGGINS JOHN LChief Executive OfficerJun 09, 2017 Option Exercise$21.0012,000252,000151,171Jun 09, 2017, 07:26 PM
HIGGINS JOHN LChief Executive OfficerJun 09, 2017 Sale$114.8712,0001,378,440139,171Jun 09, 2017, 07:26 PM
FOEHR MATTHEW WPresident and COOMay 15, 2017 Option Exercise$9.972,20021,93494,920May 15, 2017, 07:05 PM
FOEHR MATTHEW WPresident and COOMay 12, 2017 Option Exercise$9.975,62156,04198,341May 15, 2017, 07:05 PM
FOEHR MATTHEW WPresident and COOMay 12, 2017 Sale$112.195,621630,64892,720May 15, 2017, 07:05 PM
Aryeh JasonDirectorMay 12, 2017 Sale$111.8714,5821,631,332116,651May 12, 2017, 08:06 PM
Aryeh JasonDirectorMay 11, 2017 Sale$110.0422,6652,494,034131,233May 12, 2017, 08:06 PM
HIGGINS JOHN LChief Executive OfficerMar 20, 2017 Sale$109.104,000436,400139,171Mar 21, 2017, 05:49 PM
HIGGINS JOHN LChief Executive OfficerMar 08, 2017 Option Exercise$106.921,473157,493143,171Mar 10, 2017, 06:03 PM
HIGGINS JOHN LChief Executive OfficerMar 08, 2017 Option Exercise$10.0515,675157,534144,644Mar 10, 2017, 06:03 PM
HIGGINS JOHN LChief Executive OfficerMar 08, 2017 Sale$107.064,000428,240128,969Mar 10, 2017, 06:03 PM
FOEHR MATTHEW WPresident and COOMar 03, 2017 Option Exercise$9.972,00019,94092,720Mar 03, 2017, 06:54 PM
FOEHR MATTHEW WPresident and COOMar 02, 2017 Option Exercise$9.976,87968,58497,599Mar 03, 2017, 06:54 PM
FOEHR MATTHEW WPresident and COOMar 02, 2017 Sale$103.396,879711,21390,720Mar 03, 2017, 06:54 PM
Aryeh JasonDirectorFeb 28, 2017 Sale$107.587,000753,060153,898Feb 28, 2017, 08:30 PM
Aryeh JasonDirectorFeb 27, 2017 Sale$106.0025,0002,650,000160,898Feb 28, 2017, 08:30 PM
Korenberg Matthew EVP, Finance and CFOFeb 24, 2017 Option Exercise$100.381,051105,49911,505Feb 28, 2017, 06:27 PM
Korenberg Matthew EVP, Finance and CFOFeb 15, 2017 Option Exercise$104.2839140,7739,106Feb 28, 2017, 06:27 PM
Korenberg Matthew EVP, Finance and CFOAug 06, 2016 Option Exercise$123.3060975,0909,457Feb 28, 2017, 06:27 PM
FOEHR MATTHEW WPresident and COOFeb 15, 2017 Option Exercise$104.282,367246,83181,395Feb 28, 2017, 06:27 PM
FOEHR MATTHEW WPresident and COOFeb 24, 2017 Option Exercise$100.382,733274,33983,176Feb 28, 2017, 06:27 PM
HIGGINS JOHN LChief Executive OfficerFeb 15, 2017 Option Exercise$104.284,304448,821120,379Feb 28, 2017, 06:26 PM
HIGGINS JOHN LChief Executive OfficerFeb 24, 2017 Option Exercise$100.384,783480,118122,745Feb 28, 2017, 06:26 PM
Korenberg Matthew EVP, Finance and CFODec 30, 2016 Option Exercise$86.37403,45510,106Jan 03, 2017, 04:38 PM
Aryeh JasonDirectorNov 25, 2016 Sale$106.963,478372,007185,898Nov 25, 2016, 05:58 PM
Aryeh JasonDirectorNov 22, 2016 Sale$107.4015,0011,611,062189,376Nov 25, 2016, 05:58 PM
Aryeh JasonDirectorNov 18, 2016 Sale$105.005,000525,000204,377Nov 18, 2016, 04:48 PM
Aryeh JasonDirectorNov 16, 2016 Sale$106.331,330141,419209,377Nov 18, 2016, 04:48 PM
Davis Todd CDirectorOct 31, 2016 Option Exercise$45.6613,980638,36270,189Nov 01, 2016, 08:18 PM
HIGGINS JOHN LChief Executive OfficerSep 22, 2016 Sale$117.343,000352,020122,664Sep 23, 2016, 04:19 PM
KOZARICH JOHN WDirectorSep 07, 2016 Sale$115.001,000115,00039,983Sep 09, 2016, 04:06 PM
KOZARICH JOHN WDirectorSep 01, 2016 Option Exercise$45.601,66675,97040,983Sep 09, 2016, 04:05 PM
KOZARICH JOHN WDirectorSep 01, 2016 Sale$105.401,666175,59740,783Sep 06, 2016, 06:07 PM
FOEHR MATTHEW WPresident and COOAug 08, 2016 Option Exercise$9.974,12541,12683,037Aug 09, 2016, 04:58 PM
FOEHR MATTHEW WPresident and COOAug 05, 2016 Option Exercise$9.9712,500124,62591,412Aug 09, 2016, 04:58 PM
FOEHR MATTHEW WPresident and COOAug 05, 2016 Sale$122.1412,5001,526,75078,912Aug 09, 2016, 04:58 PM
Berkman Charles SVP, Gen. Counsel & SecretaryAug 05, 2016 Option Exercise$54.7630,3471,661,85741,731Aug 09, 2016, 04:58 PM
Berkman Charles SVP, Gen. Counsel & SecretaryAug 05, 2016 Sale$123.1622,0672,717,77229,647Aug 09, 2016, 04:58 PM
KOZARICH JOHN WDirectorAug 01, 2016 Sale$137.571,000137,56941,783Aug 02, 2016, 07:46 PM
Korenberg Matthew EVP, Finance and CFOJun 30, 2016 Option Exercise$87.1019617,07210,066Jul 05, 2016, 07:58 PM
Herman Melanie JDirector of AccountingJun 30, 2016 Option Exercise$87.1015713,6753,454Jul 05, 2016, 07:56 PM
KOZARICH JOHN WDirectorJul 01, 2016 Sale$121.401,000121,40242,883Jul 05, 2016, 07:56 PM
KOZARICH JOHN WDirectorJun 01, 2016 Sale$117.421,000117,41943,083Jun 03, 2016, 04:41 PM
Herman Melanie JDirector of AccountingMay 18, 2016 Sale$120.5033440,2473,297May 19, 2016, 06:28 PM
Aryeh JasonDirectorMay 06, 2016 Sale$118.5215,0001,777,830210,707May 09, 2016, 08:00 AM
Aryeh JasonDirectorMay 05, 2016 Sale$120.2110,0001,202,120225,707May 09, 2016, 08:00 AM
KOZARICH JOHN WDirectorMay 02, 2016 Sale$121.571,000121,56843,911May 03, 2016, 05:34 PM
KOZARICH JOHN WDirectorApr 06, 2016 Sale$115.005,000575,00044,711Apr 07, 2016, 05:30 PM
FOEHR MATTHEW WPresident and COOMar 17, 2016 Option Exercise$9.978,65086,24183,062Mar 17, 2016, 07:56 PM
FOEHR MATTHEW WPresident and COOMar 17, 2016 Sale$96.706,400618,88076,662Mar 17, 2016, 07:56 PM
Aryeh JasonDirectorMar 08, 2016 Sale$102.4950051,245235,707Mar 09, 2016, 06:26 PM
Aryeh JasonDirectorMar 07, 2016 Sale$101.075,629568,895236,207Mar 09, 2016, 06:26 PM
HIGGINS JOHN LChief Executive OfficerMar 08, 2016 Option Exercise$21.006,000126,000125,664Mar 09, 2016, 06:26 PM
HIGGINS JOHN LChief Executive OfficerMar 07, 2016 Sale$102.4710,8331,110,027120,220Mar 09, 2016, 06:26 PM
HIGGINS JOHN LChief Executive OfficerFeb 15, 2016 Option Exercise$85.972,492214,237130,497Feb 16, 2016, 07:34 PM
FOEHR MATTHEW WPresident and COOFeb 15, 2016 Option Exercise$85.971,642141,16376,662Feb 16, 2016, 07:34 PM
Herman Melanie JDirector of AccountingFeb 15, 2016 Option Exercise$85.9716013,7553,631Feb 16, 2016, 07:33 PM
KOZARICH JOHN WDirectorJan 20, 2016 Option Exercise$59.401,66698,96051,377Jan 22, 2016, 07:24 PM
KOZARICH JOHN WDirectorJan 20, 2016 Sale$94.941,666158,17351,077Jan 22, 2016, 07:24 PM
Herman Melanie JDirector of AccountingDec 31, 2015 Option Exercise$82.5314011,5543,291Jan 04, 2016, 05:24 PM
Aryeh JasonDirectorNov 11, 2015 Sale$101.493,000304,470241,836Nov 13, 2015, 05:29 PM
Herman Melanie JDirector of AccountingNov 11, 2015 Option Exercise$47.297,719365,03410,870Nov 13, 2015, 05:28 PM
Herman Melanie JDirector of AccountingNov 11, 2015 Sale$101.007,719779,6193,151Nov 13, 2015, 05:28 PM
KNOTT DAVID MDirectorAug 17, 2015 Sale$95.984,000383,93766,152Aug 19, 2015, 06:00 AM
KNOTT DAVID MDirectorAug 12, 2015 Sale$96.4580077,163971,300Aug 14, 2015, 12:53 PM
KNOTT DAVID MDirectorAug 13, 2015 Sale$96.207,225695,01430,771Aug 14, 2015, 12:53 PM
KNOTT DAVID MDirectorAug 13, 2015 Sale$96.2027,3002,626,143196,186Aug 14, 2015, 12:53 PM
KNOTT DAVID MDirectorAug 13, 2015 Sale$96.202,000192,391969,300Aug 14, 2015, 12:53 PM
KNOTT DAVID MDirectorAug 12, 2015 Sale$96.452,600250,78137,996Aug 14, 2015, 12:53 PM
KNOTT DAVID MDirectorAug 12, 2015 Sale$96.459,875952,486223,486Aug 14, 2015, 12:53 PM
KNOTT DAVID MDirectorAug 07, 2015 Sale$99.0120019,80340,596Aug 11, 2015, 06:51 AM
HIGGINS JOHN LChief Executive OfficerAug 06, 2015 Sale$110.794,666516,946121,378Aug 07, 2015, 04:22 PM
Davis Todd CDirectorAug 06, 2015 Option Exercise$11.8119,670232,28855,449Aug 06, 2015, 07:49 PM
Berkman Charles SVP, Gen. Counsel & SecretaryJul 13, 2015 Option Exercise$53.101,00053,10027,454Jul 14, 2015, 07:35 PM
Berkman Charles SVP, Gen. Counsel & SecretaryJul 10, 2015 Option Exercise$12.7014,067178,68740,521Jul 14, 2015, 07:35 PM
Berkman Charles SVP, Gen. Counsel & SecretaryJul 10, 2015 Sale$99.1414,0671,394,61038,117Jul 14, 2015, 07:35 PM
Berkman Charles SVP, Gen. Counsel & SecretaryJun 30, 2015 Option Exercise$45.6746521,23726,454Jul 01, 2015, 12:36 PM
Herman Melanie JInterim CFOJun 30, 2015 Option Exercise$45.671657,5363,151Jul 01, 2015, 12:36 PM
FOEHR MATTHEW WPresident and COOJun 29, 2015 Option Exercise$9.972,50024,92572,628Jun 30, 2015, 05:39 PM
FOEHR MATTHEW WPresident and COOJun 26, 2015 Option Exercise$9.9712,500124,62582,628Jun 30, 2015, 05:39 PM
FOEHR MATTHEW WPresident and COOJun 26, 2015 Sale$100.9712,5001,262,12570,128Jun 30, 2015, 05:39 PM
FOEHR MATTHEW WPresident and COOJun 22, 2015 Option Exercise$9.9725,046249,70991,174Jun 24, 2015, 06:52 PM
FOEHR MATTHEW WPresident and COOJun 22, 2015 Sale$96.4523,0462,222,81586,628Jun 24, 2015, 06:52 PM
Herman Melanie JInterim CFOJun 10, 2015 Option Exercise$38.034,125156,8857,111Jun 11, 2015, 06:17 PM
Herman Melanie JInterim CFOJun 10, 2015 Sale$93.504,125385,6882,986Jun 11, 2015, 06:17 PM
HIGGINS JOHN LChief Executive OfficerJun 09, 2015 Sale$92.8810,000928,809129,844Jun 11, 2015, 06:13 PM
Aryeh JasonDirectorJun 04, 2015 Sale$92.681,640151,995244,836Jun 08, 2015, 08:43 PM
Aryeh JasonDirectorMay 20, 2015 Sale$87.651,00087,650246,476May 20, 2015, 05:28 PM
Aryeh JasonDirectorMay 19, 2015 Sale$88.822,240198,957247,476May 20, 2015, 05:28 PM
Aryeh JasonDirectorMay 18, 2015 Sale$86.746,000520,440249,716May 20, 2015, 05:28 PM
DeSilva Nishan MVP, Finance & Strategy and CFOMay 13, 2015 Option Exercise$18.2623,905436,40834,430May 14, 2015, 05:39 PM
DeSilva Nishan MVP, Finance & Strategy and CFOMay 12, 2015 Option Exercise$17.4223,520409,66436,496May 14, 2015, 05:39 PM
DeSilva Nishan MVP, Finance & Strategy and CFOMay 14, 2015 Option Exercise$74.4220,9381,558,20643,220May 14, 2015, 05:39 PM
DeSilva Nishan MVP, Finance & Strategy and CFOMay 12, 2015 Sale$84.6323,5201,990,40322,282May 14, 2015, 05:39 PM
DeSilva Nishan MVP, Finance & Strategy and CFOMay 14, 2015 Sale$83.8420,9381,755,44222,282May 14, 2015, 05:39 PM
DeSilva Nishan MVP, Finance & Strategy and CFOMay 13, 2015 Sale$83.2723,9051,990,67122,282May 14, 2015, 05:39 PM
Patel SunilDirectorMar 19, 2015 Sale$74.424,591341,66237,100Mar 20, 2015, 04:44 PM
Berkman Charles SVP, Gen. Counsel & SecretaryMar 16, 2015 Option Exercise$20.325,264106,93930,119Mar 18, 2015, 04:32 PM
Berkman Charles SVP, Gen. Counsel & SecretaryMar 16, 2015 Sale$74.5411,264839,64925,989Mar 18, 2015, 04:32 PM
Berkman Charles SVP, Gen. Counsel & SecretaryDec 31, 2014 Option Exercise$45.231265,69927,433Mar 18, 2015, 04:28 PM
Herman Melanie JDirector of AccountingMar 02, 2015 Sale$60.6953532,4692,986Mar 03, 2015, 04:04 PM
Herman Melanie JDirector of AccountingDec 31, 2014 Option Exercise$45.231034,6592,831Feb 25, 2015, 06:00 PM
Herman Melanie JDirector of AccountingFeb 19, 2015 Sale$57.8451029,4983,521Feb 20, 2015, 04:49 PM
DeSilva Nishan MVP, Corporate DevelopmentFeb 10, 2015 Sale$56.342,300129,58216,359Feb 11, 2015, 08:06 PM
Berkman Charles SVP, Gen. Counsel & SecretaryDec 31, 2014 Buy$45.231265,69927,433Jan 05, 2015, 07:47 PM
FOEHR MATTHEW WEVP and COODec 31, 2014 Buy$45.23462,08155,016Jan 05, 2015, 07:46 PM
Herman Melanie JDirector of AccountingDec 31, 2014 Buy$45.231034,6592,831Jan 05, 2015, 07:46 PM
KOZARICH JOHN WDirectorOct 15, 2014 Buy$45.682,00091,36049,286Oct 15, 2014, 07:02 PM
FOEHR MATTHEW WEVP and COOOct 13, 2014 Option Exercise$9.971,0009,97054,970Oct 14, 2014, 01:48 PM
FOEHR MATTHEW WEVP and COOOct 10, 2014 Buy$44.91853,81753,970Oct 14, 2014, 01:48 PM
Sabba Stephen LDirectorOct 09, 2014 Buy$43.122,00086,23023,697Oct 14, 2014, 01:03 PM
KNOTT DAVID MDirectorOct 09, 2014 Buy$43.014,000172,02969,227Oct 14, 2014, 01:03 PM
Sabba Stephen LDirectorOct 09, 2014 Option Exercise$43.122,00086,23023,697Oct 10, 2014, 03:03 PM
KNOTT DAVID MDirectorOct 09, 2014 Option Exercise$43.014,000172,02969,227Oct 10, 2014, 02:29 PM
Aryeh JasonDirectorOct 09, 2014 Buy$42.9911,000472,890255,716Oct 09, 2014, 07:04 PM
KOZARICH JOHN WDirectorOct 07, 2014 Option Exercise$8.582,50021,45047,286Oct 09, 2014, 01:50 PM
Aryeh JasonDirectorOct 01, 2014 Option Exercise$32.307,335236,92060,695Oct 01, 2014, 06:24 PM
Aryeh JasonDirectorSep 25, 2014 Option Exercise$11.6520,300236,58453,360Sep 29, 2014, 01:50 PM
HIGGINS JOHN LPresident & CEOAug 15, 2014 Buy$54.971,00054,970120,099Aug 15, 2014, 02:51 PM
Herman Melanie JDirector of AccountingJun 30, 2014 Buy$43.79984,2922,728Jul 01, 2014, 12:16 PM
Berkman Charles SVP, Gen. Counsel & SecretaryJun 30, 2014 Buy$43.7932914,40827,307Jul 01, 2014, 12:16 PM
FOEHR MATTHEW WEVP and COOJun 30, 2014 Buy$43.7942818,74353,885Jul 01, 2014, 12:16 PM
Herman Melanie JDirector of AccountingJun 09, 2014 Option Exercise$12.491,10013,7413,480Jun 10, 2014, 04:29 PM
Herman Melanie JDirector of AccountingJun 09, 2014 Sale$69.681,10076,6482,630Jun 10, 2014, 04:29 PM
Berkman Charles SVP, Gen. Counsel & SecretaryMay 27, 2014 Option Exercise$18.812,49947,00728,644May 28, 2014, 06:03 PM
Berkman Charles SVP, Gen. Counsel & SecretaryMay 27, 2014 Sale$66.907,166479,43426,978May 28, 2014, 06:03 PM
BVF PARTNERS L P/ILSee Explanation of ResponsesMar 25, 2014 Sale$69.9510,203713,734130,175Mar 26, 2014, 07:28 PM
BVF PARTNERS L P/ILSee Explanation of ResponsesMar 25, 2014 Sale$69.9518,0191,260,489230,125Mar 26, 2014, 07:28 PM
BVF PARTNERS L P/ILSee Explanation of ResponsesMar 24, 2014 Sale$70.1718,3061,284,483140,378Mar 26, 2014, 07:28 PM
BVF PARTNERS L P/ILSee Explanation of ResponsesMar 24, 2014 Sale$70.1731,6982,224,163248,144Mar 26, 2014, 07:28 PM
Davis Todd CDirectorMar 19, 2014 Sale$79.635,000398,14732,536Mar 20, 2014, 06:40 PM
Davis Todd CDirectorMar 18, 2014 Sale$79.452,500198,63737,536Mar 20, 2014, 06:40 PM
LAMATTINA JOHN LDirectorMar 18, 2014 Option Exercise$8.975,00044,85026,356Mar 20, 2014, 06:40 PM
LAMATTINA JOHN LDirectorMar 18, 2014 Sale$78.835,000394,15021,356Mar 20, 2014, 06:40 PM
Sabba Stephen LDirectorFeb 27, 2014 Sale$72.2550036,12520,546Feb 28, 2014, 11:37 AM
KNOTT DAVID MDirectorFeb 20, 2014 Sale$72.9790065,6761,843Feb 21, 2014, 10:43 AM
BVF PARTNERS L P/IL10% OwnerFeb 18, 2014 Sale$74.66153,75111,478,4501,855,083Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 20, 2014 Sale$73.0518,6151,359,787279,842Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 18, 2014 Sale$74.6616,3311,219,209174,636Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 19, 2014 Sale$73.032,771202,37584,749Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 18, 2014 Sale$74.6616,9151,262,808307,921Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 19, 2014 Sale$73.0357,3704,189,9211,797,713Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 19, 2014 Sale$73.035,395394,015169,241Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 20, 2014 Sale$73.055,359391,46479,390Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 19, 2014 Sale$73.039,464691,187298,457Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 20, 2014 Sale$73.05112,3698,208,3191,685,344Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 18, 2014 Sale$74.6614,0031,045,40987,520Feb 20, 2014, 08:00 PM
BVF PARTNERS L P/IL10% OwnerFeb 20, 2014 Sale$73.0510,557771,167158,684Feb 20, 2014, 08:00 PM
KNOTT DAVID MDirectorFeb 18, 2014 Sale$73.313,900285,91940,796Feb 19, 2014, 12:16 PM
KNOTT DAVID MDirectorFeb 18, 2014 Sale$73.3111,531845,368233,361Feb 19, 2014, 12:16 PM
KNOTT DAVID MDirectorFeb 14, 2014 Sale$77.106,700516,58344,696Feb 19, 2014, 12:16 PM
KNOTT DAVID MDirectorFeb 14, 2014 Sale$77.1019,7691,524,229244,892Feb 19, 2014, 12:16 PM
Aryeh JasonDirectorFeb 14, 2014 Sale$78.879,500749,265244,716Feb 14, 2014, 08:20 PM
Aryeh JasonDirectorFeb 13, 2014 Sale$77.436,700518,779254,216Feb 14, 2014, 08:20 PM
Aryeh JasonDirectorFeb 12, 2014 Sale$75.2124,1201,814,121260,916Feb 14, 2014, 08:20 PM
Sharp John PVP Finance and CFOFeb 12, 2014 Option Exercise$17.5786,9531,528,05934,333Feb 14, 2014, 08:18 PM
Sharp John PVP Finance and CFOFeb 12, 2014 Sale$74.7486,9536,498,89817,667Feb 14, 2014, 08:18 PM
Berkman Charles SVP, Gen. Counsel & SecretaryFeb 12, 2014 Option Exercise$16.1814,881240,78434,424Feb 14, 2014, 08:06 PM
Berkman Charles SVP, Gen. Counsel & SecretaryFeb 13, 2014 Option Exercise$14.472,00028,94031,645Feb 14, 2014, 08:06 PM
Berkman Charles SVP, Gen. Counsel & SecretaryFeb 12, 2014 Sale$74.5014,8811,108,63529,645Feb 14, 2014, 08:06 PM
HIGGINS JOHN LPresident & CEOFeb 12, 2014 Option Exercise$9.9616,875168,075127,974Feb 14, 2014, 08:04 PM
HIGGINS JOHN LPresident & CEOFeb 12, 2014 Sale$75.0016,8751,265,625111,099Feb 14, 2014, 08:04 PM
FOEHR MATTHEW WEVP and COOFeb 14, 2014 Option Exercise$9.9725,944258,66275,957Feb 14, 2014, 08:00 PM
FOEHR MATTHEW WEVP and COOFeb 14, 2014 Sale$79.5422,5001,789,65053,457Feb 14, 2014, 08:00 PM
HIGGINS JOHN LPresident & CEOJan 21, 2014 Option Exercise$21.009,000189,000111,099Jan 21, 2014, 08:04 PM
HIGGINS JOHN LPresident & CEOJan 16, 2014 Sale$64.0015,000960,000102,099Jan 21, 2014, 08:04 PM
FOEHR MATTHEW WEVP and COODec 31, 2013 Buy$33.92842,84945,013Jan 02, 2014, 04:48 PM
Berkman Charles SVP, Gen. Counsel & SecretaryDec 31, 2013 Buy$33.922097,08827,145Jan 02, 2014, 04:48 PM
Sharp John PVP Finance and CFODec 12, 2013 Option Exercise$9.967006,97218,367Dec 16, 2013, 05:09 PM
Sharp John PVP Finance and CFODec 12, 2013 Sale$53.4470037,40817,667Dec 16, 2013, 05:09 PM
FOEHR MATTHEW WEVP and COODec 12, 2013 Option Exercise$9.976,00059,82050,929Dec 13, 2013, 06:46 PM
FOEHR MATTHEW WEVP and COODec 12, 2013 Sale$53.406,000320,40044,929Dec 13, 2013, 06:46 PM
Sharp John PVP Finance and CFODec 06, 2013 Sale$56.086,000336,48017,667Dec 09, 2013, 06:53 PM
BVF PARTNERS L P/IL10% OwnerNov 27, 2013 Sale$57.07319,00518,207,1142,008,834Nov 29, 2013, 11:38 AM
BVF PARTNERS L P/IL10% OwnerNov 26, 2013 Sale$57.57208,50012,003,345411,271Nov 29, 2013, 11:38 AM
KOZARICH JOHN WDirectorNov 25, 2013 Option Exercise$7.111,2438,83342,969Nov 27, 2013, 11:29 AM
KOZARICH JOHN WDirectorNov 18, 2013 Option Exercise$14.864606,83641,726Nov 20, 2013, 08:46 PM
Sharp John PVP Finance and CFONov 18, 2013 Option Exercise$9.966246,21524,790Nov 20, 2013, 06:49 PM
Sharp John PVP Finance and CFONov 18, 2013 Sale$53.001,12359,51923,667Nov 20, 2013, 06:49 PM
HIGGINS JOHN LPresident & CEOOct 22, 2013 Option Exercise$16.1410,518169,763117,099Oct 22, 2013, 08:05 PM
HIGGINS JOHN LPresident & CEOOct 18, 2013 Sale$55.0010,000550,000106,581Oct 22, 2013, 08:05 PM
BVF PARTNERS L P/IL10% OwnerSep 23, 2013 Sale$44.50359,02315,976,524530,410Sep 25, 2013, 06:54 PM
KNOTT DAVID MDirectorSep 12, 2013 Sale$46.78160,0007,484,08051,396Sep 13, 2013, 03:07 PM
Berkman Charles SVP, Gen. Counsel & SecretaryAug 30, 2013 Option Exercise$17.5137,331653,69729,732Sep 04, 2013, 07:10 PM
Berkman Charles SVP, Gen. Counsel & SecretaryAug 30, 2013 Sale$47.5428,3231,346,45617,928Sep 04, 2013, 07:10 PM
Sharp John PVP Finance and CFOAug 16, 2013 Option Exercise$9.967,50074,70031,666Aug 20, 2013, 06:44 PM
Sharp John PVP Finance and CFOAug 16, 2013 Sale$42.757,500320,61924,166Aug 20, 2013, 06:44 PM
Berkman Charles SVP, Gen. Counsel & SecretaryAug 19, 2013 Option Exercise$10.054,28443,05417,928Aug 20, 2013, 06:44 PM
Berkman Charles SVP, Gen. Counsel & SecretaryAug 16, 2013 Option Exercise$9.9614,583145,24728,227Aug 20, 2013, 06:44 PM
Berkman Charles SVP, Gen. Counsel & SecretaryAug 16, 2013 Sale$42.6314,583621,73213,644Aug 20, 2013, 06:44 PM
HIGGINS JOHN LPresident & CEOAug 19, 2013 Option Exercise$16.146,556105,814116,581Aug 20, 2013, 06:44 PM
HIGGINS JOHN LPresident & CEOAug 16, 2013 Sale$42.8510,000428,500110,025Aug 20, 2013, 06:44 PM
DeSilva Nishan MVP, Corporate DevelopmentJun 28, 2013 Buy$17.361692,93415,659Jul 01, 2013, 03:27 PM
FOEHR MATTHEW WEVP and COOJun 28, 2013 Buy$17.361,05918,38444,929Jul 01, 2013, 03:27 PM
Berkman Charles SVP, Gen. Counsel & SecretaryJun 28, 2013 Buy$17.3681514,14813,644Jul 01, 2013, 03:26 PM
Berkman Charles SVP, Gen. Counsel & SecretaryMay 10, 2013 Sale$26.664,000106,64012,829May 13, 2013, 06:46 PM
BVF PARTNERS L P/IL10% OwnerJan 23, 2013 Buy$19.7839,600783,1812,163,412Jan 25, 2013, 05:17 PM
DeSilva Nishan MVP, Corporate DevelopmentDec 31, 2012 Option Exercise$14.534907,12210,490Jan 03, 2013, 08:27 PM
KOZARICH JOHN WDirectorDec 21, 2012 Option Exercise$12.063,33340,19636,948Dec 21, 2012, 05:51 PM
BVF PARTNERS L P/IL10% OwnerDec 14, 2012 Buy$18.635,386100,3652,123,812Dec 18, 2012, 04:36 PM
BVF PARTNERS L P/IL10% OwnerDec 06, 2012 Buy$17.9450,100898,9592,118,426Dec 10, 2012, 04:40 PM
FOEHR MATTHEW WEVP and COODec 05, 2012 Buy$17.993706,65637,870Dec 05, 2012, 04:53 PM
HIGGINS JOHN LPresident & CEODec 05, 2012 Buy$18.032,00036,060112,025Dec 05, 2012, 04:53 PM
KNOTT DAVID MDirectorNov 30, 2012 Sale$19.716,652131,111211,396Dec 03, 2012, 02:13 PM
KNOTT DAVID MDirectorNov 29, 2012 Sale$20.0013,348266,960218,048Dec 03, 2012, 02:13 PM
KNOTT DAVID MDirectorNov 27, 2012 Sale$19.5565,0001,270,750266,396Nov 29, 2012, 03:04 PM
KNOTT DAVID MDirectorNov 28, 2012 Sale$19.5135,000682,850231,396Nov 29, 2012, 03:04 PM
BVF PARTNERS L P/IL10% OwnerOct 31, 2012 Buy$14.994,07661,096741,627Nov 19, 2012, 05:24 PM
BVF PARTNERS L P/IL10% OwnerOct 26, 2012 Buy$15.2612,515190,926737,551Nov 19, 2012, 05:24 PM
KNOTT DAVID MDirectorAug 29, 2012 Buy$16.362,74344,8752,743Nov 15, 2012, 06:11 PM
BVF PARTNERS L P/IL10% OwnerOct 31, 2012 Buy$14.994,07661,096741,627Nov 02, 2012, 06:36 PM
BVF PARTNERS L P/IL10% OwnerOct 26, 2012 Buy$15.2612,515190,926737,551Nov 02, 2012, 06:36 PM
Berkman Charles SVP, Gen. Counsel & SecretarySep 07, 2012 Sale$18.774,24979,75414,329Sep 10, 2012, 01:55 PM
HIGGINS JOHN LPresident & CEOAug 13, 2012 Buy$16.395008,195110,025Aug 14, 2012, 07:19 PM
HIGGINS JOHN LPresident & CEOJun 29, 2012 Option Exercise$10.121,25012,654109,525Jul 03, 2012, 05:47 PM
FOEHR MATTHEW WEVP and COOJun 29, 2012 Option Exercise$10.121,25012,65437,500Jul 03, 2012, 05:46 PM
Berkman Charles SVP, Gen. Counsel & SecretaryJun 29, 2012 Option Exercise$10.121,25012,65418,578Jul 03, 2012, 05:46 PM
Aryeh JasonDirectorJun 01, 2012 Buy$11.987008,386285,036Jun 05, 2012, 12:56 PM
Sabba Stephen LDirectorJun 01, 2012 Option Exercise$12.022,00024,04017,425Jun 04, 2012, 08:28 PM
KNOTT DAVID MDirectorMay 24, 2012 Buy$11.6223,900277,718264,661May 25, 2012, 01:50 PM
KNOTT DAVID MDirectorMay 24, 2012 Buy$11.62172,1001,999,802972,100May 25, 2012, 01:50 PM
KNOTT DAVID MDirectorMay 24, 2012 Sale$11.6298,6331,146,1150May 25, 2012, 01:50 PM
KNOTT DAVID MDirectorMay 24, 2012 Sale$11.6221,200246,34441,583May 25, 2012, 01:50 PM
KNOTT DAVID MDirectorMay 24, 2012 Sale$11.6276,167885,061331,396May 25, 2012, 01:50 PM
Patel SunilDirectorMay 23, 2012 Buy$11.381,50017,07029,705May 24, 2012, 02:01 PM
HIGGINS JOHN LPresident & CEOMay 04, 2012 Buy$12.041,00012,040108,275May 08, 2012, 01:54 PM
Berkman Charles SVP, Gen. Counsel & SecretaryMar 08, 2012 Sale$15.763,60656,83217,434Mar 08, 2012, 06:24 PM
HIGGINS JOHN LPresident & CEODec 30, 2011 Option Exercise$10.092102,11989,275Jan 06, 2012, 05:21 PM
FOEHR MATTHEW WEVP and COODec 30, 2011 Option Exercise$10.091,25012,61226,250Jan 06, 2012, 05:20 PM
Berkman Charles SVP, Gen. Counsel & SecretaryDec 30, 2011 Option Exercise$10.091,23812,49115,934Jan 06, 2012, 05:19 PM
BVF PARTNERS L P/IL10% OwnerNov 21, 2011 Buy$10.5998,1711,039,631725,036Nov 22, 2011, 04:29 PM
BVF PARTNERS L P/IL10% OwnerNov 18, 2011 Buy$11.0172,669799,7951,788,226Nov 22, 2011, 04:29 PM
BVF PARTNERS L P/IL10% OwnerNov 21, 2011 Buy$10.59340,2003,602,7182,068,326Nov 22, 2011, 04:29 PM
KOZARICH JOHN WDirectorNov 11, 2011 Buy$11.791,00011,78727,098Nov 14, 2011, 07:00 PM
Sabba Stephen LDirectorNov 14, 2011 Buy$11.501,00011,50012,704Nov 14, 2011, 06:31 PM
Sabba Stephen LDirectorNov 10, 2011 Buy$11.691,00011,69011,704Nov 14, 2011, 06:31 PM
KNOTT DAVID MDirectorNov 10, 2011 Buy$11.584,00046,32054,704Nov 14, 2011, 06:29 PM
Aryeh JasonDirectorNov 10, 2011 Buy$11.011,00011,010284,336Nov 10, 2011, 07:28 PM
Aryeh JasonDirectorNov 10, 2011 Buy$10.901,00010,9005,025Nov 10, 2011, 07:28 PM
Patel SunilDirectorNov 10, 2011 Buy$11.112,50027,77428,205Nov 10, 2011, 07:20 PM
BVF PARTNERS L P/IL10% OwnerOct 26, 2011 Buy$13.916,02083,7511,741,800Oct 28, 2011, 04:55 PM
BVF PARTNERS L P/IL10% OwnerOct 21, 2011 Buy$13.934,60064,0621,738,000Oct 25, 2011, 04:22 PM
BVF PARTNERS L P/IL10% OwnerOct 20, 2011 Buy$13.9311,900165,8091,735,000Oct 20, 2011, 05:40 PM
BVF PARTNERS L P/IL10% OwnerOct 18, 2011 Buy$13.732,20030,2151,727,400Oct 20, 2011, 05:40 PM
BVF PARTNERS L P/IL10% OwnerOct 13, 2011 Buy$13.5517,258233,8801,726,000Oct 14, 2011, 04:16 PM
BVF PARTNERS L P/IL10% OwnerOct 13, 2011 Buy$13.554,99567,692605,053Oct 14, 2011, 04:16 PM
BVF PARTNERS L P/IL10% OwnerOct 12, 2011 Buy$13.6953,100726,9921,711,762Oct 14, 2011, 04:16 PM
BVF PARTNERS L P/IL10% OwnerOct 04, 2011 Buy$12.7814,400183,9611,675,562Oct 06, 2011, 05:02 PM
KNOTT DAVID MDirectorSep 01, 2011 Buy$15.215,32080,917800,000Sep 06, 2011, 04:59 PM
KNOTT DAVID MDirectorSep 01, 2011 Buy$15.212,48037,721407,563Sep 06, 2011, 04:59 PM
KNOTT DAVID MDirectorSep 01, 2011 Buy$15.2170010,64798,633Sep 06, 2011, 04:59 PM
KNOTT DAVID MDirectorSep 01, 2011 Buy$15.211,50022,815240,761Sep 06, 2011, 04:59 PM
KNOTT DAVID MDirectorAug 30, 2011 Buy$14.8370010,38197,733Sep 01, 2011, 01:26 PM
KNOTT DAVID MDirectorAug 30, 2011 Buy$14.831,40020,762238,761Sep 01, 2011, 01:26 PM
KNOTT DAVID MDirectorAug 31, 2011 Buy$14.946008,964405,083Sep 01, 2011, 01:26 PM
KNOTT DAVID MDirectorAug 30, 2011 Buy$14.835,20077,116792,980Sep 01, 2011, 01:26 PM
KNOTT DAVID MDirectorAug 31, 2011 Buy$14.942002,98897,933Sep 01, 2011, 01:26 PM
KNOTT DAVID MDirectorAug 31, 2011 Buy$14.945007,470239,261Sep 01, 2011, 01:26 PM
KNOTT DAVID MDirectorAug 31, 2011 Buy$14.941,70025,398794,680Sep 01, 2011, 01:26 PM
KNOTT DAVID MDirectorAug 30, 2011 Buy$14.831,64024,321404,483Sep 01, 2011, 01:26 PM
KNOTT DAVID MDirectorAug 29, 2011 Buy$14.2110,400147,784787,780Aug 30, 2011, 05:00 PM
KNOTT DAVID MDirectorAug 26, 2011 Buy$12.5411,159139,934397,543Aug 30, 2011, 05:00 PM
KNOTT DAVID MDirectorAug 26, 2011 Buy$12.542,60032,60495,833Aug 30, 2011, 05:00 PM
KNOTT DAVID MDirectorAug 26, 2011 Buy$12.546,60082,764234,261Aug 30, 2011, 05:00 PM
KNOTT DAVID MDirectorAug 29, 2011 Buy$14.215,30075,313402,843Aug 30, 2011, 05:00 PM
KNOTT DAVID MDirectorAug 26, 2011 Buy$12.5421,200265,848777,380Aug 30, 2011, 05:00 PM
KNOTT DAVID MDirectorAug 29, 2011 Buy$14.211,20017,05297,033Aug 30, 2011, 05:00 PM
KNOTT DAVID MDirectorAug 29, 2011 Buy$14.213,10044,051237,361Aug 30, 2011, 05:00 PM
KNOTT DAVID MDirectorAug 25, 2011 Buy$12.572,50031,42593,233Aug 26, 2011, 05:48 PM
KNOTT DAVID MDirectorAug 25, 2011 Buy$12.575,80072,906227,661Aug 26, 2011, 05:48 PM
KNOTT DAVID MDirectorAug 25, 2011 Buy$12.5719,600246,372756,180Aug 26, 2011, 05:48 PM
KNOTT DAVID MDirectorAug 25, 2011 Buy$12.5717,200216,20462,783Aug 26, 2011, 05:48 PM
KNOTT DAVID MDirectorAug 25, 2011 Buy$12.579,900124,443386,384Aug 26, 2011, 05:48 PM
KNOTT DAVID MDirectorAug 24, 2011 Buy$12.9590011,65590,733Aug 25, 2011, 04:41 PM
KNOTT DAVID MDirectorAug 24, 2011 Buy$12.952,39030,950221,861Aug 25, 2011, 04:41 PM
KNOTT DAVID MDirectorAug 24, 2011 Buy$12.957,50097,125736,580Aug 25, 2011, 04:41 PM
KNOTT DAVID MDirectorAug 23, 2011 Buy$12.185,40065,772372,484Aug 25, 2011, 04:41 PM
KNOTT DAVID MDirectorAug 24, 2011 Buy$12.952,60033,67028,300Aug 25, 2011, 04:41 PM
KNOTT DAVID MDirectorAug 23, 2011 Buy$12.181,20014,61689,833Aug 25, 2011, 04:41 PM
KNOTT DAVID MDirectorAug 24, 2011 Buy$12.954,10053,09545,583Aug 25, 2011, 04:41 PM
KNOTT DAVID MDirectorAug 23, 2011 Buy$12.183,10037,758219,471Aug 25, 2011, 04:41 PM
KNOTT DAVID MDirectorAug 24, 2011 Buy$12.954,00051,800376,484Aug 25, 2011, 04:41 PM
KNOTT DAVID MDirectorAug 23, 2011 Buy$12.1810,300125,454729,080Aug 25, 2011, 04:41 PM
KNOTT DAVID MDirectorAug 22, 2011 Buy$12.005006,000216,371Aug 24, 2011, 06:16 AM
KNOTT DAVID MDirectorAug 22, 2011 Buy$12.001,06912,828367,084Aug 24, 2011, 06:16 AM
KNOTT DAVID MDirectorAug 22, 2011 Buy$12.001,70020,400718,780Aug 24, 2011, 06:16 AM
KNOTT DAVID MDirectorAug 22, 2011 Buy$12.002002,40088,633Aug 24, 2011, 06:16 AM
KNOTT DAVID MDirectorAug 19, 2011 Buy$11.967,40088,504366,015Aug 24, 2011, 06:16 AM
KNOTT DAVID MDirectorAug 19, 2011 Buy$11.961,80021,52888,433Aug 24, 2011, 06:16 AM
KNOTT DAVID MDirectorAug 19, 2011 Buy$11.964,30051,428215,871Aug 24, 2011, 06:16 AM
KNOTT DAVID MDirectorAug 19, 2011 Buy$11.9614,300171,028717,080Aug 24, 2011, 06:16 AM
BVF PARTNERS L P/IL10% OwnerAug 19, 2011 Buy$11.9321,300254,0201,671,562Aug 22, 2011, 06:05 PM
BVF PARTNERS L P/IL10% OwnerAug 18, 2011 Buy$11.9116,571197,3711,652,562Aug 22, 2011, 06:05 PM
KNOTT DAVID MDirectorAug 17, 2011 Buy$12.352,13326,343354,515Aug 19, 2011, 03:49 PM
KNOTT DAVID MDirectorAug 17, 2011 Buy$12.356007,41085,633Aug 19, 2011, 03:49 PM
KNOTT DAVID MDirectorAug 17, 2011 Buy$12.351,20014,820209,071Aug 19, 2011, 03:49 PM
KNOTT DAVID MDirectorAug 18, 2011 Buy$11.914,10048,831358,615Aug 19, 2011, 03:49 PM
KNOTT DAVID MDirectorAug 17, 2011 Buy$12.354,20051,870694,380Aug 19, 2011, 03:49 PM
KNOTT DAVID MDirectorAug 18, 2011 Buy$11.911,00011,91086,633Aug 19, 2011, 03:49 PM
KNOTT DAVID MDirectorAug 18, 2011 Buy$11.912,50029,775211,571Aug 19, 2011, 03:49 PM
KNOTT DAVID MDirectorAug 18, 2011 Buy$11.918,400100,044702,780Aug 19, 2011, 03:49 PM
BVF PARTNERS L P/IL10% OwnerAug 11, 2011 Buy$11.191,39415,6011,636,862Aug 15, 2011, 06:24 PM
KNOTT DAVID MDirectorAug 15, 2011 Buy$11.972,40028,728690,180Aug 15, 2011, 06:00 PM
KNOTT DAVID MDirectorAug 12, 2011 Buy$11.993,44841,342351,182Aug 15, 2011, 06:00 PM
KNOTT DAVID MDirectorAug 12, 2011 Buy$11.998009,59284,733Aug 15, 2011, 06:00 PM
KNOTT DAVID MDirectorAug 12, 2011 Buy$11.992,20026,378207,171Aug 15, 2011, 06:00 PM
KNOTT DAVID MDirectorAug 15, 2011 Buy$11.971,20014,364352,382Aug 15, 2011, 06:00 PM
KNOTT DAVID MDirectorAug 12, 2011 Buy$11.997,30087,527687,780Aug 15, 2011, 06:00 PM
KNOTT DAVID MDirectorAug 15, 2011 Buy$11.973003,59185,033Aug 15, 2011, 06:00 PM
KNOTT DAVID MDirectorAug 15, 2011 Buy$11.977008,379207,871Aug 15, 2011, 06:00 PM
KNOTT DAVID MDirectorAug 10, 2011 Buy$10.8080,600870,480667,780Aug 12, 2011, 04:13 PM
KNOTT DAVID MDirectorAug 11, 2011 Buy$11.453,90044,655204,971Aug 12, 2011, 04:13 PM
KNOTT DAVID MDirectorAug 11, 2011 Buy$11.4512,700145,415680,480Aug 12, 2011, 04:13 PM
KNOTT DAVID MDirectorAug 10, 2011 Buy$10.805,60060,48025,700Aug 12, 2011, 04:13 PM
KNOTT DAVID MDirectorAug 10, 2011 Buy$10.806,90074,52041,483Aug 12, 2011, 04:13 PM
KNOTT DAVID MDirectorAug 10, 2011 Buy$10.807,40079,92082,433Aug 12, 2011, 04:13 PM
KNOTT DAVID MDirectorAug 11, 2011 Buy$11.451,90021,755347,734Aug 12, 2011, 04:13 PM
KNOTT DAVID MDirectorAug 10, 2011 Buy$10.8024,500264,600201,071Aug 12, 2011, 04:13 PM
KNOTT DAVID MDirectorAug 11, 2011 Buy$11.451,50017,17583,933Aug 12, 2011, 04:13 PM
Davis Todd CDirectorAug 10, 2011 Buy$10.9015,000163,50029,201Aug 11, 2011, 08:08 PM
Patel SunilDirectorAug 10, 2011 Buy$10.745,00053,70525,705Aug 11, 2011, 06:00 PM
Aryeh JasonDirectorAug 10, 2011 Buy$10.572,00021,140283,336Aug 11, 2011, 02:20 PM
BVF PARTNERS L P/IL10% OwnerAug 08, 2011 Buy$11.20175,8001,969,6631,354,736Aug 10, 2011, 06:28 PM
BVF PARTNERS L P/IL10% OwnerAug 10, 2011 Buy$10.91233,0002,542,6591,635,936Aug 10, 2011, 06:28 PM
BVF PARTNERS L P/IL10% OwnerAug 09, 2011 Buy$10.86133,0001,444,9121,487,736Aug 10, 2011, 06:28 PM
BVF PARTNERS L P/IL10% OwnerAug 09, 2011 Buy$10.8657,900629,026527,236Aug 10, 2011, 06:28 PM
HIGGINS JOHN LPresident & CEOJun 30, 2011 Option Exercise$7.642772,11689,065Jul 26, 2011, 06:02 PM
HIGGINS JOHN LPresident & CEODec 31, 2010 Option Exercise$7.142942,09973,788Jul 26, 2011, 06:02 PM
Aryeh JasonDirectorMay 12, 2011 Buy$10.961,72518,906281,336May 13, 2011, 05:45 PM
Aryeh JasonDirectorMar 11, 2011 Buy$9.831,0009,8303,025May 13, 2011, 05:41 PM
Aryeh JasonDirectorMar 11, 2011 Buy$9.843,00029,525270,111May 13, 2011, 05:41 PM
Aryeh JasonDirectorMar 16, 2011 Buy$9.354,00037,405276,611Mar 16, 2011, 07:14 PM
Aryeh JasonDirectorMar 15, 2011 Buy$9.491,50014,235272,611Mar 16, 2011, 07:14 PM
Aryeh JasonDirectorMar 14, 2011 Buy$9.693,50033,900271,111Mar 15, 2011, 01:22 PM
LAMATTINA JOHN LDirectorMar 11, 2011 Buy$9.8010,00098,03011,666Mar 14, 2011, 04:12 PM
Aryeh JasonDirectorMar 10, 2011 Buy$10.051,00010,0453,025Mar 14, 2011, 03:24 PM
Aryeh JasonDirectorMar 10, 2011 Buy$10.165005,080267,611Mar 14, 2011, 03:24 PM
KNOTT DAVID MDirectorMar 03, 2011 Buy$11.0213,400147,66820,100Mar 07, 2011, 05:45 PM
KNOTT DAVID MDirectorMar 03, 2011 Buy$11.0223,000253,46034,583Mar 07, 2011, 05:45 PM
KNOTT DAVID MDirectorMar 03, 2011 Buy$11.021,00011,0201,666Mar 07, 2011, 05:45 PM
KOZARICH JOHN WDirectorFeb 25, 2011 Buy$9.991,78917,87218,726Mar 03, 2011, 01:59 PM
KOZARICH JOHN WDirectorFeb 24, 2011 Buy$9.983,21132,05616,937Mar 03, 2011, 01:59 PM
Kazmi SyedVP, Bus. Dev. & Strategic PlanFeb 28, 2011 Sale$10.691,16612,45915,296Mar 01, 2011, 03:06 PM
KOZARICH JOHN WDirectorFeb 24, 2011 Option Exercise$9.983,21132,05616,937Feb 28, 2011, 07:05 PM
KOZARICH JOHN WDirectorFeb 25, 2011 Option Exercise$9.991,78917,87218,726Feb 28, 2011, 07:05 PM
KNOTT DAVID MDirectorFeb 25, 2011 Buy$10.0214,432144,60933,248Feb 28, 2011, 04:19 PM
KNOTT DAVID MDirectorFeb 24, 2011 Buy$9.9916,316162,99718,816Feb 28, 2011, 04:19 PM
KNOTT DAVID MDirectorFeb 28, 2011 Buy$10.849,252100,29242,500Feb 28, 2011, 04:19 PM
KNOTT DAVID MDirectorFeb 23, 2011 Buy$9.952,20021,890176,571Feb 25, 2011, 01:46 PM
KNOTT DAVID MDirectorFeb 23, 2011 Buy$9.9565,200648,740587,180Feb 25, 2011, 01:46 PM
KNOTT DAVID MDirectorFeb 23, 2011 Buy$9.996,70066,9336,700Feb 25, 2011, 01:46 PM
KNOTT DAVID MDirectorFeb 23, 2011 Buy$9.9521,400212,93075,033Feb 25, 2011, 01:46 PM
KNOTT DAVID MDirectorFeb 23, 2011 Sale$9.9531,331311,7430Feb 25, 2011, 01:46 PM
KNOTT DAVID MDirectorFeb 23, 2011 Sale$9.9510,382103,3010Feb 25, 2011, 01:46 PM
KNOTT DAVID MDirectorFeb 23, 2011 Sale$9.9547,087468,516345,834Feb 25, 2011, 01:46 PM
Aryeh JasonDirectorFeb 23, 2011 Buy$9.945,00049,700267,111Feb 23, 2011, 05:02 PM
Berkman Charles SVP, Gen. Counsel & SecretaryFeb 16, 2011 Sale$9.755,00048,75111,696Feb 18, 2011, 05:38 PM
KOZARICH JOHN WDirectorFeb 17, 2011 Buy$9.901,0009,90013,726Feb 17, 2011, 06:07 PM
Patel SunilDirectorFeb 16, 2011 Buy$9.2210,00092,17413,333Feb 17, 2011, 01:57 PM
KOZARICH JOHN WDirectorNov 11, 2010 Buy$1.6010,00015,95476,357Nov 12, 2010, 02:03 PM
Load More Insider Transactions
Buy Sale Option Exercise
OwnerRelationshipDateValue($)
Davis Todd CChief Executive Officer03/25/2024919,147
Sabba Stephen LDirector03/05/2024140,650
Aryeh JasonDirector03/05/2024113,840
Espinoza OctavioChief Financial Officer02/28/202471,564
Espinoza OctavioChief Financial Officer02/28/202412,384
Reardon AndrewCHIEF LEGAL OFFICER &02/15/202444,267
Korenberg Matthew EPRESIDENT & CHIEF OPERATING02/15/2024356,678
Espinoza OctavioChief Financial Officer02/15/2024110,407
Davis Todd CCHIEF EXECUTIVE OFFICER02/15/2024103,092
Korenberg Matthew EPRESIDENT & CHIEF OPERATING01/02/2024210,928
Reardon AndrewCHIEF LEGAL OFFICER &12/29/202310,867
Espinoza OctavioChief Financial Officer12/05/202375,645
Korenberg Matthew EPRESIDENT & CHIEF OPERATING12/05/2023118,266
Espinoza OctavioChief Financial Officer10/01/202320,732
Davis Todd CCHIEF EXECUTIVE OFFICER09/22/2023237,529
Reardon AndrewCHIEF LEGAL OFFICER &08/10/202361,651
Korenberg Matthew EPRESIDENT & CHIEF OPERATING06/30/202321,349
Espinoza OctavioChief Financial Officer06/30/202321,292
Davis Todd CCHIEF EXECUTIVE OFFICER06/09/202330,979
KOZARICH JOHN WDirector05/16/2023343,081
Sabba Stephen LDirector05/10/2023494,225
KOZARICH JOHN WDirector05/08/2023120,599
KOZARICH JOHN WDirector05/08/2023490,628
Reardon AndrewSee Remarks03/24/202320,977
Korenberg Matthew EPresident & COO02/15/2023210,912
Espinoza OctavioChief Financial Officer02/15/202361,960
Espinoza OctavioChief Financial Officer12/30/202215,614
Korenberg Matthew EPresident & COO12/28/2022255,813
HIGGINS JOHN LDirector12/28/2022350,608
HIGGINS JOHN LDirector12/16/2022618,657
HIGGINS JOHN LDirector12/12/2022255,571
HIGGINS JOHN LDirector12/12/2022255,600
Korenberg Matthew EPresident & COO11/30/2022261,930
HIGGINS JOHN LChief Executive Officer11/30/2022714,639
Espinoza OctavioChief Financial Officer11/30/202286,532
Reardon AndrewSee Remarks11/30/202278,222
HIGGINS JOHN LChief Executive Officer11/18/2022127,800
HIGGINS JOHN LChief Executive Officer11/17/2022783,173
Espinoza OctavioChief Financial Officer11/09/2022128,283
HIGGINS JOHN LChief Executive Officer09/16/202288,060
HIGGINS JOHN LChief Executive Officer09/15/2022180,000
HIGGINS JOHN LChief Executive Officer09/16/2022268,050
Korenberg Matthew EEVP,Finance & Strategy and CFO06/30/202212,437
HIGGINS JOHN LChief Executive Officer06/30/202212,437
FOEHR MATTHEW WPresident and COO05/13/2022206,910
HIGGINS JOHN LChief Executive Officer05/09/2022175,360
FOEHR MATTHEW WPresident and COO02/15/2022438,569
HIGGINS JOHN LChief Executive Officer02/15/2022732,557
Korenberg Matthew EEVP,Finance & Strategy and CFO02/15/2022421,378
Korenberg Matthew EEVP,Finance & Strategy and CFO01/26/2022412,431
HIGGINS JOHN LChief Executive Officer01/26/20221,050,744
Berkman Charles SSVP, Gen. Counsel & Secretary01/26/2022245,094
FOEHR MATTHEW WPresident and COO01/26/2022582,610
LAMATTINA JOHN LDirector11/16/2021156,170
LAMATTINA JOHN LDirector11/16/2021782,579
HIGGINS JOHN LChief Executive Officer11/12/2021481,500
FOEHR MATTHEW WPresident and COO11/11/2021347,818
FOEHR MATTHEW WPresident and COO11/11/20211,819,259
FOEHR MATTHEW WPresident and COO08/04/2021291,745
FOEHR MATTHEW WPresident and COO08/04/2021969,509
HIGGINS JOHN LChief Executive Officer06/30/202121,220
Korenberg Matthew EEVP,Finance & Strategy and CFO06/30/202121,220
KOZARICH JOHN WDirector05/11/202150,267
KOZARICH JOHN WDirector05/11/202148,930
KOZARICH JOHN WDirector02/22/202125,300
Berkman Charles SSVP, Gen. Counsel & Secretary02/15/2021175,047
FOEHR MATTHEW WPresident and COO02/15/2021534,281
HIGGINS JOHN LChief Executive Officer02/15/2021898,862
Korenberg Matthew EEVP,Finance & Strategy and CFO02/15/2021398,210
Davis Todd CDirector02/11/2021484,681
Davis Todd CDirector02/10/20211,083,411
Sabba Stephen LDirector02/09/2021166,138
Sabba Stephen LDirector02/09/20213,059,123
HIGGINS JOHN LChief Executive Officer02/05/2021602,999
HIGGINS JOHN LChief Executive Officer02/05/20211,394,017
HIGGINS JOHN LChief Executive Officer02/05/202111,119,228
Berkman Charles SSVP, Gen. Counsel & Secretary02/04/20213,230,369
FOEHR MATTHEW WPresident and COO02/04/20211,050,890
FOEHR MATTHEW WPresident and COO02/04/20217,878,582
HIGGINS JOHN LChief Executive Officer01/25/20211,160,870
HIGGINS JOHN LChief Executive Officer01/27/20211,236,400
HIGGINS JOHN LChief Executive Officer01/25/2021723,500
HIGGINS JOHN LChief Executive Officer01/25/20217,950,000
HIGGINS JOHN LChief Executive Officer01/27/20217,280,000
FOEHR MATTHEW WPresident and COO01/25/2021518,733
Korenberg Matthew EEVP,Finance & Strategy and CFO01/25/2021329,337
Berkman Charles SSVP, Gen. Counsel & Secretary01/25/2021208,943
Davis Todd CDirector01/27/2021278,756
HIGGINS JOHN LChief Executive Officer12/31/202018,851
HIGGINS JOHN LChief Executive Officer12/08/2020147,296
HIGGINS JOHN LChief Executive Officer12/08/2020147,303
HIGGINS JOHN LChief Executive Officer11/09/2020200,991
HIGGINS JOHN LChief Executive Officer11/09/2020201,000
Patel SunilDirector11/02/202082,520
FOEHR MATTHEW WPresident and COO08/24/20201,710
FOEHR MATTHEW WPresident and COO08/21/2020163,338
FOEHR MATTHEW WPresident and COO08/24/20208,649
FOEHR MATTHEW WPresident and COO08/21/2020815,544
HIGGINS JOHN LChief Executive Officer07/07/2020302,098
Berkman Charles SSVP, Gen. Counsel & Secretary06/30/202021,189
Korenberg Matthew EEVP,Finance & Strategy and CFO06/30/202021,189
Berkman Charles SSVP, Gen. Counsel & Secretary06/04/20201,321,771
Korenberg Matthew EEVP,Finance & Strategy and CFO02/15/2019140,923
FOEHR MATTHEW WPresident and COO02/15/2019341,550
HIGGINS JOHN LChief Executive Officer02/15/2019594,269
FOEHR MATTHEW WPresident and COO03/13/202043,840
FOEHR MATTHEW WPresident and COO02/27/2020141,941
FOEHR MATTHEW WPresident and COO02/27/2020794,750
HIGGINS JOHN LChief Executive Officer02/15/2020497,429
HIGGINS JOHN LChief Executive Officer02/13/2020479,261
HIGGINS JOHN LChief Executive Officer02/13/2020479,325
FOEHR MATTHEW WPresident and COO02/15/2020241,714
FOEHR MATTHEW WPresident and COO02/14/2020104,546
FOEHR MATTHEW WPresident and COO02/13/202010,872
FOEHR MATTHEW WPresident and COO02/14/2020692,467
Berkman Charles SSVP, Gen. Counsel & Secretary02/15/202085,660
Korenberg Matthew EEVP,Finance & Strategy and CFO12/20/2019223,809
Berkman Charles SSVP, Gen. Counsel & Secretary12/20/2019119,739
FOEHR MATTHEW WPresident and COO12/20/2019386,849
HIGGINS JOHN LChief Executive Officer12/20/2019714,517
FOEHR MATTHEW WPresident and COO11/12/201921,942
FOEHR MATTHEW WPresident and COO09/05/201922,030
Aryeh JasonDirector09/03/201965,258
Korenberg Matthew EEVP,Finance & Strategy and CFO09/03/201943,091
FOEHR MATTHEW WPresident and COO08/12/201925,493
Aryeh JasonDirector08/05/201967,146
Berkman Charles SSVP, Gen. Counsel & Secretary08/05/201974,013
Davis Todd CDirector08/02/201993,594
LAMATTINA JOHN LDirector08/01/201980,958
LAMATTINA JOHN LDirector08/01/201980,750
Patel SunilDirector08/02/201995,980
Sabba Stephen LDirector07/31/2019386,395
HIGGINS JOHN LChief Executive Officer07/31/2019176,582
Aryeh JasonDirector07/31/201970,122
Aryeh JasonDirector07/30/2019300,663
Aryeh JasonDirector07/29/201926,503
Berkman Charles SSVP, Gen. Counsel & Secretary06/28/201917,659
Korenberg Matthew EEVP,Finance & Strategy and CFO06/28/201917,659
Aryeh JasonDirector06/11/201926,753
FOEHR MATTHEW WPresident and COO06/11/201922,008
HIGGINS JOHN LChief Executive Officer05/31/2019108,202
Aryeh JasonDirector05/31/201954,255
Aryeh JasonDirector05/30/201927,503
Aryeh JasonDirector05/29/201927,753
Aryeh JasonDirector05/20/201928,003
Aryeh JasonDirector05/14/201928,128
HIGGINS JOHN LChief Executive Officer05/14/2019283,750
KOZARICH JOHN WDirector05/14/201944,700
KOZARICH JOHN WDirector05/14/2019282,300
FOEHR MATTHEW WPresident and COO03/14/2019148,493
Aryeh JasonDirector03/13/201922,727
HIGGINS JOHN LChief Executive Officer03/13/2019285,725
FOEHR MATTHEW WPresident and COO01/23/2019287,051
HIGGINS JOHN LChief Executive Officer01/23/2019756,192
Korenberg Matthew EEVP,Finance & Strategy and CFO01/23/2019148,108
Berkman Charles SSVP, Gen. Counsel & Secretary01/10/2019187,029
HIGGINS JOHN LChief Executive Officer01/10/2019545,371
Berkman Charles SSVP, Gen. Counsel & Secretary12/17/201874,528
FOEHR MATTHEW WPresident and COO12/12/201879,750
Berkman Charles SSVP, Gen. Counsel & Secretary10/24/201865,462
Davis Todd CDirector10/12/2018525,021
Berkman Charles SSVP, Gen. Counsel & Secretary10/11/201828,940
Davis Todd CDirector10/08/2018634,977
KOZARICH JOHN WDirector10/01/2018687,610
FOEHR MATTHEW WPresident and COO10/01/2018194,457
FOEHR MATTHEW WPresident and COO10/01/20183,286,560
Berkman Charles SSVP, Gen. Counsel & Secretary09/17/2018282,369
Berkman Charles SSVP, Gen. Counsel & Secretary09/17/2018705,183
Sabba Stephen LDirector09/04/201866,150
Sabba Stephen LDirector09/04/20181,275,250
FOEHR MATTHEW WPresident and COO09/04/2018184,049
FOEHR MATTHEW WPresident and COO09/04/20183,060,084
Berkman Charles SSVP, Gen. Counsel & Secretary09/04/20181,358,796
Berkman Charles SSVP, Gen. Counsel & Secretary09/04/20184,951,063
LAMATTINA JOHN LDirector09/04/201841,788
LAMATTINA JOHN LDirector09/04/2018850,292
HIGGINS JOHN LChief Executive Officer08/30/2018903,875
Korenberg Matthew EEVP,Finance & Strategy and CFO08/29/2018990,017
Korenberg Matthew EEVP,Finance & Strategy and CFO08/29/20184,712,058
Aryeh JasonDirector08/16/2018264,600
Aryeh JasonDirector08/17/20186,495,554
Davis Todd CDirector08/17/2018758,497
Davis Todd CDirector08/16/20181,399,506
HIGGINS JOHN LChief Executive Officer08/17/2018188,009
HIGGINS JOHN LChief Executive Officer08/16/201843,511
HIGGINS JOHN LChief Executive Officer08/17/20183,157,299
HIGGINS JOHN LChief Executive Officer08/16/20185,190,263
Patel SunilDirector08/16/2018451,058
Patel SunilDirector08/16/201810,150,825
Korenberg Matthew EEVP,Finance & Strategy and CFO08/06/2018189,555
KOZARICH JOHN WDirector07/02/2018518,700
Korenberg Matthew EEVP,Finance & Strategy and CFO06/29/201821,210
Berkman Charles SSVP, Gen. Counsel & Secretary06/29/201821,210
LAMATTINA JOHN LDirector06/04/201850,120
LAMATTINA JOHN LDirector06/04/2018778,040
HIGGINS JOHN LChief Executive Officer05/15/2018200,217
HIGGINS JOHN LChief Executive Officer05/15/20182,232,491
FOEHR MATTHEW WPresident and COO05/10/2018139,026
FOEHR MATTHEW WPresident and COO05/10/20181,488,687
KOZARICH JOHN WDirector04/02/2018401,063
Sabba Stephen LDirector03/12/2018112,414
Aryeh JasonDirector03/09/2018705,900
Aryeh JasonDirector03/08/2018612,094
LAMATTINA JOHN LDirector03/05/201833,750
LAMATTINA JOHN LDirector03/05/2018536,605
Korenberg Matthew EEVP,Finance & Strategy and CFO03/06/201891,228
Berkman Charles SSVP, Gen. Counsel & Secretary03/06/201865,021
HIGGINS JOHN LChief Executive Officer03/06/2018494,624
FOEHR MATTHEW WPresident and COO03/06/2018241,673
Aryeh JasonDirector02/23/2018529,635
Davis Todd CDirector02/27/20181,873,711
Davis Todd CDirector02/26/2018742,535
FOEHR MATTHEW WPresident and COO02/23/201888,785
FOEHR MATTHEW WPresident and COO02/23/2018832,823
Berkman Charles SSVP, Gen. Counsel & Secretary02/15/2018162,838
FOEHR MATTHEW WPresident and COO02/15/2018575,750
HIGGINS JOHN LChief Executive Officer02/15/2018981,118
HIGGINS JOHN LChief Executive Officer02/15/20181,413,279
Korenberg Matthew EEVP,Finance & Strategy and CFO02/15/2018106,882
HIGGINS JOHN LChief Executive Officer01/24/20183,712,500
HIGGINS JOHN LChief Executive Officer01/19/2018262,259
HIGGINS JOHN LChief Executive Officer01/19/20184,318,906
KOZARICH JOHN WDirector01/10/2018362,500
Korenberg Matthew EVP, Finance and CFO12/28/2017212,150
FOEHR MATTHEW WPresident and COO12/28/2017411,959
HIGGINS JOHN LChief Executive Officer12/28/2017720,893
Berkman Charles SVP, Gen. Counsel & Secretary12/28/2017162,926
Sabba Stephen LDirector12/20/2017126,956
Aryeh JasonDirector11/17/20173,421,368
HIGGINS JOHN LChief Executive Officer11/17/2017316,888
LAMATTINA JOHN LDirector11/17/201740,480
LAMATTINA JOHN LDirector11/17/2017559,160
KOZARICH JOHN WDirector11/16/2017708,550
Korenberg Matthew EVP, Finance and CFO11/17/2017935,510
HIGGINS JOHN LChief Executive Officer11/16/2017750,991
HIGGINS JOHN LChief Executive Officer10/13/2017249,462
HIGGINS JOHN LChief Executive Officer10/13/2017249,537
HIGGINS JOHN LChief Executive Officer09/05/2017105,000
HIGGINS JOHN LChief Executive Officer09/05/2017650,000
Aryeh JasonDirector08/23/2017255,980
FOEHR MATTHEW WPresident and COO08/09/201769,292
FOEHR MATTHEW WPresident and COO08/09/2017777,823
Berkman Charles SVP, Gen. Counsel & Secretary08/09/20172,364,667
HIGGINS JOHN LChief Executive Officer08/08/2017115,143
HIGGINS JOHN LChief Executive Officer08/08/2017685,375
Korenberg Matthew EVP, Finance and CFO08/06/201774,335
Berkman Charles SVP, Gen. Counsel & Secretary06/30/201721,171
Korenberg Matthew EVP, Finance and CFO06/30/201721,171
HIGGINS JOHN LChief Executive Officer06/21/201797,986
HIGGINS JOHN LChief Executive Officer06/21/2017559,920
HIGGINS JOHN LChief Executive Officer06/09/2017252,000
HIGGINS JOHN LChief Executive Officer06/09/20171,378,440
FOEHR MATTHEW WPresident and COO05/15/201721,934
FOEHR MATTHEW WPresident and COO05/12/201756,041
FOEHR MATTHEW WPresident and COO05/12/2017630,648
Aryeh JasonDirector05/12/20171,631,332
Aryeh JasonDirector05/11/20172,494,034
HIGGINS JOHN LChief Executive Officer03/20/2017436,400
HIGGINS JOHN LChief Executive Officer03/08/2017157,493
HIGGINS JOHN LChief Executive Officer03/08/2017157,534
HIGGINS JOHN LChief Executive Officer03/08/2017428,240
FOEHR MATTHEW WPresident and COO03/03/201719,940
FOEHR MATTHEW WPresident and COO03/02/201768,584
FOEHR MATTHEW WPresident and COO03/02/2017711,213
Aryeh JasonDirector02/28/2017753,060
Aryeh JasonDirector02/27/20172,650,000
Korenberg Matthew EVP, Finance and CFO02/24/2017105,499
Korenberg Matthew EVP, Finance and CFO02/15/201740,773
Korenberg Matthew EVP, Finance and CFO08/06/201675,090
FOEHR MATTHEW WPresident and COO02/15/2017246,831
FOEHR MATTHEW WPresident and COO02/24/2017274,339
HIGGINS JOHN LChief Executive Officer02/15/2017448,821
HIGGINS JOHN LChief Executive Officer02/24/2017480,118
Korenberg Matthew EVP, Finance and CFO12/30/20163,455
Aryeh JasonDirector11/25/2016372,007
Aryeh JasonDirector11/22/20161,611,062
Aryeh JasonDirector11/18/2016525,000
Aryeh JasonDirector11/16/2016141,419
Davis Todd CDirector10/31/2016638,362
HIGGINS JOHN LChief Executive Officer09/22/2016352,020
KOZARICH JOHN WDirector09/07/2016115,000
KOZARICH JOHN WDirector09/01/201675,970
KOZARICH JOHN WDirector09/01/2016175,597
FOEHR MATTHEW WPresident and COO08/08/201641,126
FOEHR MATTHEW WPresident and COO08/05/2016124,625
FOEHR MATTHEW WPresident and COO08/05/20161,526,750
Berkman Charles SVP, Gen. Counsel & Secretary08/05/20161,661,857
Berkman Charles SVP, Gen. Counsel & Secretary08/05/20162,717,772
KOZARICH JOHN WDirector08/01/2016137,569
Korenberg Matthew EVP, Finance and CFO06/30/201617,072
Herman Melanie JDirector of Accounting06/30/201613,675
KOZARICH JOHN WDirector07/01/2016121,402
KOZARICH JOHN WDirector06/01/2016117,419
Herman Melanie JDirector of Accounting05/18/201640,247
Aryeh JasonDirector05/06/20161,777,830
Aryeh JasonDirector05/05/20161,202,120
KOZARICH JOHN WDirector05/02/2016121,568
KOZARICH JOHN WDirector04/06/2016575,000
FOEHR MATTHEW WPresident and COO03/17/201686,241
FOEHR MATTHEW WPresident and COO03/17/2016618,880
Aryeh JasonDirector03/08/201651,245
Aryeh JasonDirector03/07/2016568,895
HIGGINS JOHN LChief Executive Officer03/08/2016126,000
HIGGINS JOHN LChief Executive Officer03/07/20161,110,027
HIGGINS JOHN LChief Executive Officer02/15/2016214,237
FOEHR MATTHEW WPresident and COO02/15/2016141,163
Herman Melanie JDirector of Accounting02/15/201613,755
KOZARICH JOHN WDirector01/20/201698,960
KOZARICH JOHN WDirector01/20/2016158,173
Herman Melanie JDirector of Accounting12/31/201511,554
Aryeh JasonDirector11/11/2015304,470
Herman Melanie JDirector of Accounting11/11/2015365,034
Herman Melanie JDirector of Accounting11/11/2015779,619
KNOTT DAVID MDirector08/17/2015383,937
KNOTT DAVID MDirector08/12/201577,163
KNOTT DAVID MDirector08/13/2015695,014
KNOTT DAVID MDirector08/13/20152,626,143
KNOTT DAVID MDirector08/13/2015192,391
KNOTT DAVID MDirector08/12/2015250,781
KNOTT DAVID MDirector08/12/2015952,486
KNOTT DAVID MDirector08/07/201519,803
HIGGINS JOHN LChief Executive Officer08/06/2015516,946
Davis Todd CDirector08/06/2015232,288
Berkman Charles SVP, Gen. Counsel & Secretary07/13/201553,100
Berkman Charles SVP, Gen. Counsel & Secretary07/10/2015178,687
Berkman Charles SVP, Gen. Counsel & Secretary07/10/20151,394,610
Berkman Charles SVP, Gen. Counsel & Secretary06/30/201521,237
Herman Melanie JInterim CFO06/30/20157,536
FOEHR MATTHEW WPresident and COO06/29/201524,925
FOEHR MATTHEW WPresident and COO06/26/2015124,625
FOEHR MATTHEW WPresident and COO06/26/20151,262,125
FOEHR MATTHEW WPresident and COO06/22/2015249,709
FOEHR MATTHEW WPresident and COO06/22/20152,222,815
Herman Melanie JInterim CFO06/10/2015156,885
Herman Melanie JInterim CFO06/10/2015385,688
HIGGINS JOHN LChief Executive Officer06/09/2015928,809
Aryeh JasonDirector06/04/2015151,995
Aryeh JasonDirector05/20/201587,650
Aryeh JasonDirector05/19/2015198,957
Aryeh JasonDirector05/18/2015520,440
DeSilva Nishan MVP, Finance & Strategy and CFO05/13/2015436,408
DeSilva Nishan MVP, Finance & Strategy and CFO05/12/2015409,664
DeSilva Nishan MVP, Finance & Strategy and CFO05/14/20151,558,206
DeSilva Nishan MVP, Finance & Strategy and CFO05/12/20151,990,403
DeSilva Nishan MVP, Finance & Strategy and CFO05/14/20151,755,442
DeSilva Nishan MVP, Finance & Strategy and CFO05/13/20151,990,671
Patel SunilDirector03/19/2015341,662
Berkman Charles SVP, Gen. Counsel & Secretary03/16/2015106,939
Berkman Charles SVP, Gen. Counsel & Secretary03/16/2015839,649
Berkman Charles SVP, Gen. Counsel & Secretary12/31/20145,699
Herman Melanie JDirector of Accounting03/02/201532,469
Herman Melanie JDirector of Accounting12/31/20144,659
Herman Melanie JDirector of Accounting02/19/201529,498
DeSilva Nishan MVP, Corporate Development02/10/2015129,582
Berkman Charles SVP, Gen. Counsel & Secretary12/31/20145,699
FOEHR MATTHEW WEVP and COO12/31/20142,081
Herman Melanie JDirector of Accounting12/31/20144,659
KOZARICH JOHN WDirector10/15/201491,360
FOEHR MATTHEW WEVP and COO10/13/20149,970
FOEHR MATTHEW WEVP and COO10/10/20143,817
Sabba Stephen LDirector10/09/201486,230
KNOTT DAVID MDirector10/09/2014172,029
Sabba Stephen LDirector10/09/201486,230
KNOTT DAVID MDirector10/09/2014172,029
Aryeh JasonDirector10/09/2014472,890
KOZARICH JOHN WDirector10/07/201421,450
Aryeh JasonDirector10/01/2014236,920
Aryeh JasonDirector09/25/2014236,584
HIGGINS JOHN LPresident & CEO08/15/201454,970
Herman Melanie JDirector of Accounting06/30/20144,292
Berkman Charles SVP, Gen. Counsel & Secretary06/30/201414,408
FOEHR MATTHEW WEVP and COO06/30/201418,743
Herman Melanie JDirector of Accounting06/09/201413,741
Herman Melanie JDirector of Accounting06/09/201476,648
Berkman Charles SVP, Gen. Counsel & Secretary05/27/201447,007
Berkman Charles SVP, Gen. Counsel & Secretary05/27/2014479,434
BVF PARTNERS L P/ILSee Explanation of Responses03/25/2014713,734
BVF PARTNERS L P/ILSee Explanation of Responses03/25/20141,260,489
BVF PARTNERS L P/ILSee Explanation of Responses03/24/20141,284,483
BVF PARTNERS L P/ILSee Explanation of Responses03/24/20142,224,163
Davis Todd CDirector03/19/2014398,147
Davis Todd CDirector03/18/2014198,637
LAMATTINA JOHN LDirector03/18/201444,850
LAMATTINA JOHN LDirector03/18/2014394,150
Sabba Stephen LDirector02/27/201436,125
KNOTT DAVID MDirector02/20/201465,676
BVF PARTNERS L P/IL10% Owner02/18/201411,478,450
BVF PARTNERS L P/IL10% Owner02/20/20141,359,787
BVF PARTNERS L P/IL10% Owner02/18/20141,219,209
BVF PARTNERS L P/IL10% Owner02/19/2014202,375
BVF PARTNERS L P/IL10% Owner02/18/20141,262,808
BVF PARTNERS L P/IL10% Owner02/19/20144,189,921
BVF PARTNERS L P/IL10% Owner02/19/2014394,015
BVF PARTNERS L P/IL10% Owner02/20/2014391,464
BVF PARTNERS L P/IL10% Owner02/19/2014691,187
BVF PARTNERS L P/IL10% Owner02/20/20148,208,319
BVF PARTNERS L P/IL10% Owner02/18/20141,045,409
BVF PARTNERS L P/IL10% Owner02/20/2014771,167
KNOTT DAVID MDirector02/18/2014285,919
KNOTT DAVID MDirector02/18/2014845,368
KNOTT DAVID MDirector02/14/2014516,583
KNOTT DAVID MDirector02/14/20141,524,229
Aryeh JasonDirector02/14/2014749,265
Aryeh JasonDirector02/13/2014518,779
Aryeh JasonDirector02/12/20141,814,121
Sharp John PVP Finance and CFO02/12/20141,528,059
Sharp John PVP Finance and CFO02/12/20146,498,898
Berkman Charles SVP, Gen. Counsel & Secretary02/12/2014240,784
Berkman Charles SVP, Gen. Counsel & Secretary02/13/201428,940
Berkman Charles SVP, Gen. Counsel & Secretary02/12/20141,108,635
HIGGINS JOHN LPresident & CEO02/12/2014168,075
HIGGINS JOHN LPresident & CEO02/12/20141,265,625
FOEHR MATTHEW WEVP and COO02/14/2014258,662
FOEHR MATTHEW WEVP and COO02/14/20141,789,650
HIGGINS JOHN LPresident & CEO01/21/2014189,000
HIGGINS JOHN LPresident & CEO01/16/2014960,000
FOEHR MATTHEW WEVP and COO12/31/20132,849
Berkman Charles SVP, Gen. Counsel & Secretary12/31/20137,088
Sharp John PVP Finance and CFO12/12/20136,972
Sharp John PVP Finance and CFO12/12/201337,408
FOEHR MATTHEW WEVP and COO12/12/201359,820
FOEHR MATTHEW WEVP and COO12/12/2013320,400
Sharp John PVP Finance and CFO12/06/2013336,480
BVF PARTNERS L P/IL10% Owner11/27/201318,207,114
BVF PARTNERS L P/IL10% Owner11/26/201312,003,345
KOZARICH JOHN WDirector11/25/20138,833
KOZARICH JOHN WDirector11/18/20136,836
Sharp John PVP Finance and CFO11/18/20136,215
Sharp John PVP Finance and CFO11/18/201359,519
HIGGINS JOHN LPresident & CEO10/22/2013169,763
HIGGINS JOHN LPresident & CEO10/18/2013550,000
BVF PARTNERS L P/IL10% Owner09/23/201315,976,524
KNOTT DAVID MDirector09/12/20137,484,080
Berkman Charles SVP, Gen. Counsel & Secretary08/30/2013653,697
Berkman Charles SVP, Gen. Counsel & Secretary08/30/20131,346,456
Sharp John PVP Finance and CFO08/16/201374,700
Sharp John PVP Finance and CFO08/16/2013320,619
Berkman Charles SVP, Gen. Counsel & Secretary08/19/201343,054
Berkman Charles SVP, Gen. Counsel & Secretary08/16/2013145,247
Berkman Charles SVP, Gen. Counsel & Secretary08/16/2013621,732
HIGGINS JOHN LPresident & CEO08/19/2013105,814
HIGGINS JOHN LPresident & CEO08/16/2013428,500
DeSilva Nishan MVP, Corporate Development06/28/20132,934
FOEHR MATTHEW WEVP and COO06/28/201318,384
Berkman Charles SVP, Gen. Counsel & Secretary06/28/201314,148
Berkman Charles SVP, Gen. Counsel & Secretary05/10/2013106,640
BVF PARTNERS L P/IL10% Owner01/23/2013783,181
DeSilva Nishan MVP, Corporate Development12/31/20127,122
KOZARICH JOHN WDirector12/21/201240,196
BVF PARTNERS L P/IL10% Owner12/14/2012100,365
BVF PARTNERS L P/IL10% Owner12/06/2012898,959
FOEHR MATTHEW WEVP and COO12/05/20126,656
HIGGINS JOHN LPresident & CEO12/05/201236,060
KNOTT DAVID MDirector11/30/2012131,111
KNOTT DAVID MDirector11/29/2012266,960
KNOTT DAVID MDirector11/27/20121,270,750
KNOTT DAVID MDirector11/28/2012682,850
BVF PARTNERS L P/IL10% Owner10/31/201261,096
BVF PARTNERS L P/IL10% Owner10/26/2012190,926
KNOTT DAVID MDirector08/29/201244,875
BVF PARTNERS L P/IL10% Owner10/31/201261,096
BVF PARTNERS L P/IL10% Owner10/26/2012190,926
Berkman Charles SVP, Gen. Counsel & Secretary09/07/201279,754
HIGGINS JOHN LPresident & CEO08/13/20128,195
HIGGINS JOHN LPresident & CEO06/29/201212,654
FOEHR MATTHEW WEVP and COO06/29/201212,654
Berkman Charles SVP, Gen. Counsel & Secretary06/29/201212,654
Aryeh JasonDirector06/01/20128,386
Sabba Stephen LDirector06/01/201224,040
KNOTT DAVID MDirector05/24/2012277,718
KNOTT DAVID MDirector05/24/20121,999,802
KNOTT DAVID MDirector05/24/20121,146,115
KNOTT DAVID MDirector05/24/2012246,344
KNOTT DAVID MDirector05/24/2012885,061
Patel SunilDirector05/23/201217,070
HIGGINS JOHN LPresident & CEO05/04/201212,040
Berkman Charles SVP, Gen. Counsel & Secretary03/08/201256,832
HIGGINS JOHN LPresident & CEO12/30/20112,119
FOEHR MATTHEW WEVP and COO12/30/201112,612
Berkman Charles SVP, Gen. Counsel & Secretary12/30/201112,491
BVF PARTNERS L P/IL10% Owner11/21/20111,039,631
BVF PARTNERS L P/IL10% Owner11/18/2011799,795
BVF PARTNERS L P/IL10% Owner11/21/20113,602,718
KOZARICH JOHN WDirector11/11/201111,787
Sabba Stephen LDirector11/14/201111,500
Sabba Stephen LDirector11/10/201111,690
KNOTT DAVID MDirector11/10/201146,320
Aryeh JasonDirector11/10/201111,010
Aryeh JasonDirector11/10/201110,900
Patel SunilDirector11/10/201127,774
BVF PARTNERS L P/IL10% Owner10/26/201183,751
BVF PARTNERS L P/IL10% Owner10/21/201164,062
BVF PARTNERS L P/IL10% Owner10/20/2011165,809
BVF PARTNERS L P/IL10% Owner10/18/201130,215
BVF PARTNERS L P/IL10% Owner10/13/2011233,880
BVF PARTNERS L P/IL10% Owner10/13/201167,692
BVF PARTNERS L P/IL10% Owner10/12/2011726,992
BVF PARTNERS L P/IL10% Owner10/04/2011183,961
KNOTT DAVID MDirector09/01/201180,917
KNOTT DAVID MDirector09/01/201137,721
KNOTT DAVID MDirector09/01/201110,647
KNOTT DAVID MDirector09/01/201122,815
KNOTT DAVID MDirector08/30/201110,381
KNOTT DAVID MDirector08/30/201120,762
KNOTT DAVID MDirector08/31/20118,964
KNOTT DAVID MDirector08/30/201177,116
KNOTT DAVID MDirector08/31/20112,988
KNOTT DAVID MDirector08/31/20117,470
KNOTT DAVID MDirector08/31/201125,398
KNOTT DAVID MDirector08/30/201124,321
KNOTT DAVID MDirector08/29/2011147,784
KNOTT DAVID MDirector08/26/2011139,934
KNOTT DAVID MDirector08/26/201132,604
KNOTT DAVID MDirector08/26/201182,764
KNOTT DAVID MDirector08/29/201175,313
KNOTT DAVID MDirector08/26/2011265,848
KNOTT DAVID MDirector08/29/201117,052
KNOTT DAVID MDirector08/29/201144,051
KNOTT DAVID MDirector08/25/201131,425
KNOTT DAVID MDirector08/25/201172,906
KNOTT DAVID MDirector08/25/2011246,372
KNOTT DAVID MDirector08/25/2011216,204
KNOTT DAVID MDirector08/25/2011124,443
KNOTT DAVID MDirector08/24/201111,655
KNOTT DAVID MDirector08/24/201130,950
KNOTT DAVID MDirector08/24/201197,125
KNOTT DAVID MDirector08/23/201165,772
KNOTT DAVID MDirector08/24/201133,670
KNOTT DAVID MDirector08/23/201114,616
KNOTT DAVID MDirector08/24/201153,095
KNOTT DAVID MDirector08/23/201137,758
KNOTT DAVID MDirector08/24/201151,800
KNOTT DAVID MDirector08/23/2011125,454
KNOTT DAVID MDirector08/22/20116,000
KNOTT DAVID MDirector08/22/201112,828
KNOTT DAVID MDirector08/22/201120,400
KNOTT DAVID MDirector08/22/20112,400
KNOTT DAVID MDirector08/19/201188,504
KNOTT DAVID MDirector08/19/201121,528
KNOTT DAVID MDirector08/19/201151,428
KNOTT DAVID MDirector08/19/2011171,028
BVF PARTNERS L P/IL10% Owner08/19/2011254,020
BVF PARTNERS L P/IL10% Owner08/18/2011197,371
KNOTT DAVID MDirector08/17/201126,343
KNOTT DAVID MDirector08/17/20117,410
KNOTT DAVID MDirector08/17/201114,820
KNOTT DAVID MDirector08/18/201148,831
KNOTT DAVID MDirector08/17/201151,870
KNOTT DAVID MDirector08/18/201111,910
KNOTT DAVID MDirector08/18/201129,775
KNOTT DAVID MDirector08/18/2011100,044
BVF PARTNERS L P/IL10% Owner08/11/201115,601
KNOTT DAVID MDirector08/15/201128,728
KNOTT DAVID MDirector08/12/201141,342
KNOTT DAVID MDirector08/12/20119,592
KNOTT DAVID MDirector08/12/201126,378
KNOTT DAVID MDirector08/15/201114,364
KNOTT DAVID MDirector08/12/201187,527
KNOTT DAVID MDirector08/15/20113,591
KNOTT DAVID MDirector08/15/20118,379
KNOTT DAVID MDirector08/10/2011870,480
KNOTT DAVID MDirector08/11/201144,655
KNOTT DAVID MDirector08/11/2011145,415
KNOTT DAVID MDirector08/10/201160,480
KNOTT DAVID MDirector08/10/201174,520
KNOTT DAVID MDirector08/10/201179,920
KNOTT DAVID MDirector08/11/201121,755
KNOTT DAVID MDirector08/10/2011264,600
KNOTT DAVID MDirector08/11/201117,175
Davis Todd CDirector08/10/2011163,500
Patel SunilDirector08/10/201153,705
Aryeh JasonDirector08/10/201121,140
BVF PARTNERS L P/IL10% Owner08/08/20111,969,663
BVF PARTNERS L P/IL10% Owner08/10/20112,542,659
BVF PARTNERS L P/IL10% Owner08/09/20111,444,912
BVF PARTNERS L P/IL10% Owner08/09/2011629,026
HIGGINS JOHN LPresident & CEO06/30/20112,116
HIGGINS JOHN LPresident & CEO12/31/20102,099
Aryeh JasonDirector05/12/201118,906
Aryeh JasonDirector03/11/20119,830
Aryeh JasonDirector03/11/201129,525
Aryeh JasonDirector03/16/201137,405
Aryeh JasonDirector03/15/201114,235
Aryeh JasonDirector03/14/201133,900
LAMATTINA JOHN LDirector03/11/201198,030
Aryeh JasonDirector03/10/201110,045
Aryeh JasonDirector03/10/20115,080
KNOTT DAVID MDirector03/03/2011147,668
KNOTT DAVID MDirector03/03/2011253,460
KNOTT DAVID MDirector03/03/2011