. (DNAI)
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Market Cap: -
As of 12/31/69 07:00 PM EST. Market closed.
. (DNAI)
-
- (-)
Market Cap: -
As of 12/31/69 07:00 PM EST. Market closed.
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INSIDER TRANSACTIONS FOR
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| Vivo Opportunity, LLC | Director | Jul 01, 2022 | Option Exercise | $55.00 | 2,735,853 | 150,471,915 | 0 | Jul 01, 2022, 04:59 PM |
| Vivo Opportunity, LLC | Director | Jul 01, 2022 | Option Exercise | $55.00 | 161,712 | 8,894,160 | 0 | Jul 01, 2022, 04:59 PM |
| Vivo Opportunity, LLC | Director | Jul 01, 2022 | Option Exercise | $55.00 | 431,947 | 23,757,085 | 0 | Jul 01, 2022, 04:59 PM |
| ORBIMED ADVISORS LLC | Director | Jul 01, 2022 | Option Exercise | $55.00 | 1,964,770 | 108,062,350 | 0 | Jul 01, 2022, 04:50 PM |
| Ashiya Mona | Director | Jul 01, 2022 | Option Exercise | $55.00 | 1,964,770 | 108,062,350 | 0 | Jul 01, 2022, 04:46 PM |
| Aggarwal Gaurav | Director | Jul 01, 2022 | Option Exercise | $55.00 | 2,735,853 | 150,471,915 | 0 | Jul 01, 2022, 04:45 PM |
| Sinclair Andrew | Director | Jul 01, 2022 | Option Exercise | $55.00 | 1,314,127 | 72,276,985 | 0 | Jul 01, 2022, 04:44 PM |
| Klencke Barbara | Chief Medical Officer | Jul 01, 2022 | Option Exercise | $55.00 | 5,000 | 275,000 | 0 | Jul 01, 2022, 04:43 PM |
| Klencke Barbara | Chief Medical Officer | Jul 01, 2022 | Option Exercise | $55.00 | 10,000 | 550,000 | 0 | Jul 01, 2022, 04:43 PM |
| Allen Andrew R | Director | Jul 01, 2022 | Option Exercise | $55.00 | 1,650 | 90,750 | 0 | Jul 01, 2022, 04:38 PM |
| Collard Craig A | Director | Jul 01, 2022 | Option Exercise | $55.00 | 13,500 | 742,500 | 0 | Jul 01, 2022, 04:37 PM |
| DILLY STEPHEN GEORGE | CEO and President | Jul 01, 2022 | Option Exercise | $55.00 | 5,000 | 275,000 | 0 | Jul 01, 2022, 04:35 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Apr 06, 2022 | Option Exercise | $12.05 | 6,347 | 76,481 | 6,347 | Apr 07, 2022, 04:12 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Apr 05, 2022 | Option Exercise | $12.05 | 100 | 1,205 | 100 | Apr 07, 2022, 04:12 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Apr 05, 2022 | Sale | $37.09 | 100 | 3,709 | 0 | Apr 07, 2022, 04:12 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Apr 06, 2022 | Sale | $37.25 | 6,347 | 236,409 | 0 | Apr 07, 2022, 04:12 PM |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | Apr 04, 2022 | Option Exercise | $13.04 | 2,000 | 26,080 | 2,000 | Apr 04, 2022, 07:25 PM |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | Apr 04, 2022 | Sale | $35.14 | 2,000 | 70,277 | 0 | Apr 04, 2022, 07:25 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Mar 18, 2022 | Option Exercise | $12.05 | 100 | 1,205 | 100 | Mar 22, 2022, 04:15 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Mar 18, 2022 | Sale | $37.05 | 100 | 3,705 | 0 | Mar 22, 2022, 04:15 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Mar 17, 2022 | Option Exercise | $12.05 | 3,453 | 41,609 | 3,453 | Mar 17, 2022, 06:33 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Mar 17, 2022 | Sale | $37.06 | 3,453 | 127,954 | 0 | Mar 17, 2022, 06:33 PM |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | Mar 04, 2022 | Option Exercise | $13.04 | 2,000 | 26,080 | 2,000 | Mar 04, 2022, 04:12 PM |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | Mar 04, 2022 | Sale | $30.60 | 2,000 | 61,196 | 0 | Mar 04, 2022, 04:12 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Feb 07, 2022 | Option Exercise | $12.05 | 10,000 | 120,500 | 10,000 | Feb 08, 2022, 04:03 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Feb 07, 2022 | Sale | $32.32 | 10,000 | 323,225 | 0 | Feb 08, 2022, 04:03 PM |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | Feb 04, 2022 | Option Exercise | $13.04 | 2,000 | 26,080 | 2,000 | Feb 04, 2022, 04:08 PM |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | Feb 04, 2022 | Sale | $29.78 | 2,000 | 59,560 | 0 | Feb 04, 2022, 04:08 PM |
| Longitude Capital Partners III, LLC | 10% Owner | Feb 02, 2022 | Buy | $27.00 | 175,000 | 4,725,000 | 175,000 | Feb 02, 2022, 09:25 PM |
| Richardson Joshua | Director | Feb 02, 2022 | Buy | $27.00 | 175,000 | 4,725,000 | 175,000 | Feb 02, 2022, 09:24 PM |
| Sinclair Andrew | Director | Jan 31, 2022 | Buy | $27.00 | 150,000 | 4,050,000 | 1,314,127 | Feb 01, 2022, 05:04 PM |
| Sinclair Andrew | Director | Jan 28, 2022 | Option Exercise | $13.20 | 287,471 | 3,794,617 | 1,164,127 | Feb 01, 2022, 05:04 PM |
| Abingworth LLP | 10% Owner | Jan 31, 2022 | Buy | $27.00 | 150,000 | 4,050,000 | 1,314,127 | Feb 01, 2022, 05:00 PM |
| Abingworth LLP | 10% Owner | Jan 28, 2022 | Option Exercise | $13.20 | 287,471 | 3,794,617 | 1,164,127 | Feb 01, 2022, 05:00 PM |
| Vivo Opportunity, LLC | 10% Owner | Jan 31, 2022 | Buy | $27.00 | 800,000 | 21,600,000 | 2,735,853 | Jan 31, 2022, 09:30 PM |
| Aggarwal Gaurav | Director | Jan 31, 2022 | Buy | $27.00 | 800,000 | 21,600,000 | 2,735,853 | Jan 31, 2022, 06:47 PM |
| Ashiya Mona | Director | Jan 26, 2022 | Option Exercise | $13.20 | 56,244 | 742,421 | 226,704 | Jan 28, 2022, 09:23 PM |
| Ashiya Mona | Director | Jan 26, 2022 | Option Exercise | $13.20 | 431,206 | 5,691,919 | 1,511,362 | Jan 28, 2022, 09:23 PM |
| ORBIMED ADVISORS LLC | Director | Jan 26, 2022 | Option Exercise | $13.20 | 56,244 | 742,421 | 226,704 | Jan 28, 2022, 09:22 PM |
| ORBIMED ADVISORS LLC | Director | Jan 26, 2022 | Option Exercise | $13.20 | 431,206 | 5,691,919 | 1,511,362 | Jan 28, 2022, 09:22 PM |
| Vivo Opportunity, LLC | 10% Owner | Jan 26, 2022 | Option Exercise | $13.20 | 24,996 | 329,947 | 161,712 | Jan 28, 2022, 08:12 PM |
| Vivo Opportunity, LLC | 10% Owner | Jan 26, 2022 | Option Exercise | $13.20 | 107,164 | 1,414,565 | 431,947 | Jan 28, 2022, 08:12 PM |
| Vivo Opportunity, LLC | 10% Owner | Jan 26, 2022 | Option Exercise | $13.20 | 480,277 | 6,339,656 | 1,935,853 | Jan 28, 2022, 08:12 PM |
| Aggarwal Gaurav | Director | Jan 26, 2022 | Option Exercise | $13.20 | 480,277 | 6,339,656 | 1,935,853 | Jan 28, 2022, 07:53 PM |
| Thomson Mary Christina | General Counsel & Secretary | Jan 26, 2022 | Option Exercise | $13.04 | 2,000 | 26,080 | 2,000 | Jan 28, 2022, 04:47 PM |
| Thomson Mary Christina | General Counsel & Secretary | Jan 26, 2022 | Sale | $29.00 | 2,000 | 58,000 | 0 | Jan 28, 2022, 04:47 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Jan 26, 2022 | Option Exercise | $12.05 | 5,000 | 60,250 | 5,000 | Jan 28, 2022, 04:39 PM |
| Turner William D. | Chief Reg & Tech Ops Officer | Jan 26, 2022 | Sale | $27.05 | 5,000 | 135,250 | 0 | Jan 28, 2022, 04:39 PM |
| Longitude Capital Partners III, LLC | 10% Owner | Jan 25, 2022 | Option Exercise | $13.20 | 487,451 | 6,434,353 | 1,964,771 | Jan 27, 2022, 09:23 PM |
| Richardson Joshua | Director | Jan 25, 2022 | Option Exercise | $13.20 | 487,451 | 6,434,353 | 1,964,771 | Jan 27, 2022, 09:22 PM |
| Collard Craig A | Director | Nov 24, 2021 | Buy | $23.08 | 7,899 | 182,348 | 13,500 | Nov 24, 2021, 07:07 PM |
| Collard Craig A | Director | Nov 23, 2021 | Buy | $22.94 | 5,601 | 128,515 | 5,601 | Nov 24, 2021, 07:07 PM |
| DILLY STEPHEN GEORGE | CEO and President | May 19, 2021 | Buy | $17.83 | 5,000 | 89,150 | 5,000 | May 20, 2021, 06:59 PM |
| Klencke Barbara | Chief Development Officer | Aug 18, 2020 | Buy | $12.25 | 3,325 | 40,738 | 5,000 | Aug 18, 2020, 08:16 PM |
| Klencke Barbara | Chief Development Officer | Aug 18, 2020 | Buy | $12.22 | 5,950 | 72,710 | 10,000 | Aug 18, 2020, 08:16 PM |
| Klencke Barbara | Chief Development Officer | Aug 23, 2019 | Buy | $0.44 | 108,000 | 47,380 | 162,000 | Aug 26, 2019, 05:07 PM |
| Klencke Barbara | Chief Development Officer | Aug 22, 2019 | Buy | $0.45 | 54,000 | 24,295 | 54,000 | Aug 26, 2019, 05:07 PM |
| Klencke Barbara | Chief Development Officer | Aug 22, 2019 | Buy | $0.43 | 67,000 | 28,964 | 67,000 | Aug 26, 2019, 05:07 PM |
| Allen Andrew R | Director | Dec 10, 2018 | Buy | $1.64 | 66,000 | 108,240 | 66,000 | Dec 11, 2018, 05:38 PM |
| You Angie | Chief Bus. & Strat. Officer | Mar 08, 2017 | Buy | $1.43 | 30,000 | 42,900 | 133,252 | Mar 09, 2017, 06:01 PM |
| Topper James N | Director | Feb 14, 2017 | Buy | $1.35 | 5,925,926 | 8,000,000 | 5,925,926 | Feb 16, 2017, 05:11 PM |
| Chapman Wendy | SVP Clinical Operations | Mar 22, 2016 | Option Exercise | $0.97 | 3,000 | 2,907 | 3,000 | Mar 24, 2016, 05:17 PM |
| Chapman Wendy | SVP Clinical Operations | Mar 22, 2016 | Sale | $7.01 | 3,000 | 21,023 | 0 | Mar 24, 2016, 05:17 PM |
| Chapman Wendy | SVP Clinical Operations | Feb 22, 2016 | Option Exercise | $0.97 | 3,000 | 2,907 | 3,000 | Feb 24, 2016, 05:07 PM |
| Chapman Wendy | SVP Clinical Operations | Feb 22, 2016 | Sale | $7.06 | 3,000 | 21,180 | 0 | Feb 24, 2016, 05:07 PM |
| Chapman Wendy | SVP Clinical Operations | Jan 22, 2016 | Option Exercise | $0.97 | 5,000 | 4,845 | 5,000 | Jan 25, 2016, 07:20 PM |
| Chapman Wendy | SVP Clinical Operations | Jan 22, 2016 | Sale | $9.39 | 5,000 | 46,973 | 0 | Jan 25, 2016, 07:20 PM |
| Rodigueza Wendi | Chief Scientific Officer | Jan 21, 2016 | Sale | $10.32 | 1,000 | 10,323 | 157,276 | Jan 22, 2016, 04:55 PM |
| Rodigueza Wendi | Chief Scientific Officer | Jan 20, 2016 | Sale | $9.59 | 1,000 | 9,590 | 158,276 | Jan 22, 2016, 04:55 PM |
| Rodigueza Wendi | Chief Scientific Officer | Jan 22, 2016 | Sale | $9.66 | 1,000 | 9,660 | 156,276 | Jan 22, 2016, 04:55 PM |
| Glover Nicholas | CEO and President | Jan 15, 2016 | Option Exercise | $0.97 | 5,000 | 4,845 | 5,000 | Jan 19, 2016, 07:00 PM |
| Glover Nicholas | CEO and President | Jan 15, 2016 | Sale | $10.04 | 5,000 | 50,223 | 0 | Jan 19, 2016, 07:00 PM |
| Lovejoy Chandra D | SVP of Reg. Affairs & Quality | Jan 12, 2016 | Option Exercise | $0.97 | 7,551 | 7,317 | 20,973 | Jan 14, 2016, 05:16 PM |
| Lovejoy Chandra D | SVP of Reg. Affairs & Quality | Jan 12, 2016 | Sale | $11.29 | 20,973 | 236,833 | 5,562 | Jan 14, 2016, 05:16 PM |
| VIVO VENTURES VII, LLC | Former 10% holder | Jul 21, 2015 | Option Exercise | $5.22 | 2,324 | 12,120 | 2,218,270 | Jul 21, 2015, 07:06 PM |
| VIVO VENTURES VII, LLC | Former 10% holder | Jul 21, 2015 | Option Exercise | $5.22 | 106,647 | 556,164 | 2,215,946 | Jul 21, 2015, 07:06 PM |
| VIVO VENTURES VII, LLC | Former 10% holder | Jul 21, 2015 | Buy | $17.00 | 4,693 | 79,781 | 2,438,270 | Jul 21, 2015, 07:06 PM |
| VIVO VENTURES VII, LLC | Former 10% holder | Jul 21, 2015 | Buy | $17.00 | 215,307 | 3,660,219 | 2,433,577 | Jul 21, 2015, 07:06 PM |
| Vitangcol Alvin | Director | Jul 21, 2015 | Option Exercise | $5.22 | 39,889 | 208,021 | 798,762 | Jul 21, 2015, 07:05 PM |
| Topper James N | Director | Jul 21, 2015 | Option Exercise | $5.22 | 96,589 | 503,712 | 1,966,195 | Jul 21, 2015, 07:04 PM |
| Topper James N | Director | Jul 21, 2015 | Buy | $17.00 | 220,000 | 3,740,000 | 2,186,195 | Jul 21, 2015, 07:04 PM |
| Thompson Peter A. | Director | Jul 21, 2015 | Option Exercise | $5.22 | 89,159 | 464,964 | 1,814,949 | Jul 21, 2015, 07:03 PM |
| Thompson Peter A. | Director | Jul 21, 2015 | Buy | $17.00 | 175,000 | 2,975,000 | 1,989,949 | Jul 21, 2015, 07:03 PM |
| Parfet Donald R | Chairman of the Board | Jul 21, 2015 | Option Exercise | $5.22 | 819 | 4,271 | 65,779 | Jul 21, 2015, 07:02 PM |
| Parfet Donald R | Chairman of the Board | Jul 21, 2015 | Option Exercise | $5.22 | 4,119 | 21,481 | 217,903 | Jul 21, 2015, 07:02 PM |
| Parfet Donald R | Chairman of the Board | Jul 21, 2015 | Option Exercise | $5.22 | 1,552 | 8,094 | 770,045 | Jul 21, 2015, 07:02 PM |
| Parfet Donald R | Chairman of the Board | Jul 21, 2015 | Option Exercise | $5.22 | 4,413 | 23,014 | 142,255 | Jul 21, 2015, 07:02 PM |
| ORBIMED ADVISORS LLC | Director | Jul 21, 2015 | Option Exercise | $5.22 | 89,159 | 464,964 | 1,814,949 | Jul 21, 2015, 07:00 PM |
| ORBIMED ADVISORS LLC | Director | Jul 21, 2015 | Buy | $17.00 | 175,000 | 2,975,000 | 1,989,949 | Jul 21, 2015, 07:00 PM |
| CHA ALBERT | Director | Jul 21, 2015 | Option Exercise | $5.22 | 2,324 | 12,120 | 2,218,270 | Jul 21, 2015, 06:59 PM |
| CHA ALBERT | Director | Jul 21, 2015 | Option Exercise | $5.22 | 106,647 | 556,164 | 2,215,946 | Jul 21, 2015, 06:59 PM |
| CHA ALBERT | Director | Jul 21, 2015 | Buy | $17.00 | 4,693 | 79,781 | 2,438,270 | Jul 21, 2015, 06:59 PM |
| CHA ALBERT | Director | Jul 21, 2015 | Buy | $17.00 | 215,307 | 3,660,219 | 2,433,577 | Jul 21, 2015, 06:59 PM |
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Sale
Option Exercise
| Owner | Relationship | Date | Value($) |
| Vivo Opportunity, LLC | Director | 07/01/2022 | 150,471,915 |
| Vivo Opportunity, LLC | Director | 07/01/2022 | 8,894,160 |
| Vivo Opportunity, LLC | Director | 07/01/2022 | 23,757,085 |
| ORBIMED ADVISORS LLC | Director | 07/01/2022 | 108,062,350 |
| Ashiya Mona | Director | 07/01/2022 | 108,062,350 |
| Aggarwal Gaurav | Director | 07/01/2022 | 150,471,915 |
| Sinclair Andrew | Director | 07/01/2022 | 72,276,985 |
| Klencke Barbara | Chief Medical Officer | 07/01/2022 | 275,000 |
| Klencke Barbara | Chief Medical Officer | 07/01/2022 | 550,000 |
| Allen Andrew R | Director | 07/01/2022 | 90,750 |
| Collard Craig A | Director | 07/01/2022 | 742,500 |
| DILLY STEPHEN GEORGE | CEO and President | 07/01/2022 | 275,000 |
| Turner William D. | Chief Reg & Tech Ops Officer | 04/06/2022 | 76,481 |
| Turner William D. | Chief Reg & Tech Ops Officer | 04/05/2022 | 1,205 |
| Turner William D. | Chief Reg & Tech Ops Officer | 04/05/2022 | 3,709 |
| Turner William D. | Chief Reg & Tech Ops Officer | 04/06/2022 | 236,409 |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | 04/04/2022 | 26,080 |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | 04/04/2022 | 70,277 |
| Turner William D. | Chief Reg & Tech Ops Officer | 03/18/2022 | 1,205 |
| Turner William D. | Chief Reg & Tech Ops Officer | 03/18/2022 | 3,705 |
| Turner William D. | Chief Reg & Tech Ops Officer | 03/17/2022 | 41,609 |
| Turner William D. | Chief Reg & Tech Ops Officer | 03/17/2022 | 127,954 |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | 03/04/2022 | 26,080 |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | 03/04/2022 | 61,196 |
| Turner William D. | Chief Reg & Tech Ops Officer | 02/07/2022 | 120,500 |
| Turner William D. | Chief Reg & Tech Ops Officer | 02/07/2022 | 323,225 |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | 02/04/2022 | 26,080 |
| Thomson Mary Christina | General Counsel, CCO & Sec'y | 02/04/2022 | 59,560 |
| Longitude Capital Partners III, LLC | 10% Owner | 02/02/2022 | 4,725,000 |
| Richardson Joshua | Director | 02/02/2022 | 4,725,000 |
| Sinclair Andrew | Director | 01/31/2022 | 4,050,000 |
| Sinclair Andrew | Director | 01/28/2022 | 3,794,617 |
| Abingworth LLP | 10% Owner | 01/31/2022 | 4,050,000 |
| Abingworth LLP | 10% Owner | 01/28/2022 | 3,794,617 |
| Vivo Opportunity, LLC | 10% Owner | 01/31/2022 | 21,600,000 |
| Aggarwal Gaurav | Director | 01/31/2022 | 21,600,000 |
| Ashiya Mona | Director | 01/26/2022 | 742,421 |
| Ashiya Mona | Director | 01/26/2022 | 5,691,919 |
| ORBIMED ADVISORS LLC | Director | 01/26/2022 | 742,421 |
| ORBIMED ADVISORS LLC | Director | 01/26/2022 | 5,691,919 |
| Vivo Opportunity, LLC | 10% Owner | 01/26/2022 | 329,947 |
| Vivo Opportunity, LLC | 10% Owner | 01/26/2022 | 1,414,565 |
| Vivo Opportunity, LLC | 10% Owner | 01/26/2022 | 6,339,656 |
| Aggarwal Gaurav | Director | 01/26/2022 | 6,339,656 |
| Thomson Mary Christina | General Counsel & Secretary | 01/26/2022 | 26,080 |
| Thomson Mary Christina | General Counsel & Secretary | 01/26/2022 | 58,000 |
| Turner William D. | Chief Reg & Tech Ops Officer | 01/26/2022 | 60,250 |
| Turner William D. | Chief Reg & Tech Ops Officer | 01/26/2022 | 135,250 |
| Longitude Capital Partners III, LLC | 10% Owner | 01/25/2022 | 6,434,353 |
| Richardson Joshua | Director | 01/25/2022 | 6,434,353 |
| Collard Craig A | Director | 11/24/2021 | 182,348 |
| Collard Craig A | Director | 11/23/2021 | 128,515 |
| DILLY STEPHEN GEORGE | CEO and President | 05/19/2021 | 89,150 |
| Klencke Barbara | Chief Development Officer | 08/18/2020 | 40,738 |
| Klencke Barbara | Chief Development Officer | 08/18/2020 | 72,710 |
| Klencke Barbara | Chief Development Officer | 08/23/2019 | 47,380 |
| Klencke Barbara | Chief Development Officer | 08/22/2019 | 24,295 |
| Klencke Barbara | Chief Development Officer | 08/22/2019 | 28,964 |
| Allen Andrew R | Director | 12/10/2018 | 108,240 |
| You Angie | Chief Bus. & Strat. Officer | 03/08/2017 | 42,900 |
| Topper James N | Director | 02/14/2017 | 8,000,000 |
| Chapman Wendy | SVP Clinical Operations | 03/22/2016 | 2,907 |
| Chapman Wendy | SVP Clinical Operations | 03/22/2016 | 21,023 |
| Chapman Wendy | SVP Clinical Operations | 02/22/2016 | 2,907 |
| Chapman Wendy | SVP Clinical Operations | 02/22/2016 | 21,180 |
| Chapman Wendy | SVP Clinical Operations | 01/22/2016 | 4,845 |
| Chapman Wendy | SVP Clinical Operations | 01/22/2016 | 46,973 |
| Rodigueza Wendi | Chief Scientific Officer | 01/21/2016 | 10,323 |
| Rodigueza Wendi | Chief Scientific Officer | 01/20/2016 | 9,590 |
| Rodigueza Wendi | Chief Scientific Officer | 01/22/2016 | 9,660 |
| Glover Nicholas | CEO and President | 01/15/2016 | 4,845 |
| Glover Nicholas | CEO and President | 01/15/2016 | 50,223 |
| Lovejoy Chandra D | SVP of Reg. Affairs & Quality | 01/12/2016 | 7,317 |
| Lovejoy Chandra D | SVP of Reg. Affairs & Quality | 01/12/2016 | 236,833 |
| VIVO VENTURES VII, LLC | Former 10% holder | 07/21/2015 | 12,120 |
| VIVO VENTURES VII, LLC | Former 10% holder | 07/21/2015 | 556,164 |
| VIVO VENTURES VII, LLC | Former 10% holder | 07/21/2015 | 79,781 |
| VIVO VENTURES VII, LLC | Former 10% holder | 07/21/2015 | 3,660,219 |
| Vitangcol Alvin | Director | 07/21/2015 | 208,021 |
| Topper James N | Director | 07/21/2015 | 503,712 |
| Topper James N | Director | 07/21/2015 | 3,740,000 |
| Thompson Peter A. | Director | 07/21/2015 | 464,964 |
| Thompson Peter A. | Director | 07/21/2015 | 2,975,000 |
| Parfet Donald R | Chairman of the Board | 07/21/2015 | 4,271 |
| Parfet Donald R | Chairman of the Board | 07/21/2015 | 21,481 |
| Parfet Donald R | Chairman of the Board | 07/21/2015 | 8,094 |
| Parfet Donald R | Chairman of the Board | 07/21/2015 | 23,014 |
| ORBIMED ADVISORS LLC | Director | 07/21/2015 | 464,964 |
| ORBIMED ADVISORS LLC | Director | 07/21/2015 | 2,975,000 |
| CHA ALBERT | Director | 07/21/2015 | 12,120 |
| CHA ALBERT | Director | 07/21/2015 | 556,164 |
| CHA ALBERT | Director | 07/21/2015 | 79,781 |
| CHA ALBERT | Director | 07/21/2015 | 3,660,219 |
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