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Capstone Holding Corp. (CAPS) OTC MARKETS

$5.20 - (-)

Market Cap: $819572

As of 11/28/23 12:00 AM EST. Market closed.

(CAPS)

Capstone Holding Corp. (CAPS)
OTC MARKETS

$5.20
- (-)

Market Cap: $819572

As of 11/28/23 12:00 AM EST. Market closed.

Add to Portfolio

capstone therapeutics (otcqb: caps) is a clinical stage biotechnology company developing a family of new peptide drugs to serve cardiovascular patients with high cholesterol and triglyceride levels otherwise unaddressable through standard therapy. capstone holds an fda orphan drug designation for its lead molecule, aem-28, for homozygous familial hypercholesterolemia (hofh) and may also target ... read more

capstone therapeutics (otcqb: caps) is a clinical stage biotechnology company developing a family of new peptide drugs to serve cardiovascular patients with high cholesterol and triglyceride levels otherwise unaddressable through standard therapy. capstone holds an fda orphan drug designation for its lead molecule, aem-28, for homozygous familial hypercholesterolemia (hofh) and may also target indications in acute coronary syndrome, peripheral artery disease and type 2 diabetes. read less

COMPANY PROFILE
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
John Holliman
Full Time Employees
8
URL
Address
1275 W Washington St Ste 101, Arizona, Tempe, 85281-1859.
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
CEO
John Holliman
Full Time Employees
8
Address
1275 W Washington St Ste 101, Arizona, Tempe, 85281-1859.
PRICE CHART FOR CAPSTONE HOLDING CORP
1w
1m
3m
6m
YTD
1y
5y
MAX
From: To:
NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
-
Previous Close
$5.20
Days Range
$5 - $5.25
52 week range
$4.90 - $20
Volume
379
Avg. Volume (30 days)
0
Market Cap
$819572
Dividend Yield
-
P/E
-
Shares Outstanding
157,610
Open
-
Previous Close
$5.20
Days Range
$5 - $5.25
52 week range
$4.90 - $20
Volume
379
Avg. Volume (30 days)
0
Market Cap
$819572
Dividend Yield
-
P/E
-
Shares Outstanding
157,610
FINANCIAL STATEMENTS FOR CAPSTONE HOLDING CORP
LOADING...

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

INSIDER TRANSACTIONS FOR CAPSTONE HOLDING CORP
OwnerRelationshipDateTransactionCost# SharesValue($)Total SharesForm 4
SUBIN NEIL S10% OwnerDec 21, 2018 Buy$0.05103,0005,356727,100Dec 28, 2018, 12:36 PM
SUBIN NEIL S10% OwnerDec 21, 2018 Sale$0.05206,00010,7122,708,484Dec 28, 2018, 12:36 PM
MILLER LLOYD I III10% OwnerOct 05, 2017 Sale$0.06100,0006,000624,100Oct 10, 2017, 03:00 PM
BVF PARTNERS L P/ILSee Explanation of ResponsesJul 14, 2017 Sale$0.06242,23614,5341,377,652Jul 18, 2017, 07:59 PM
BVF PARTNERS L P/ILSee Explanation of ResponsesJul 14, 2017 Sale$0.063,993,637239,6180Jul 18, 2017, 07:59 PM
BVF PARTNERS L P/ILSee Explanation of ResponsesJul 14, 2017 Sale$0.06105,7136,343890,487Jul 18, 2017, 07:59 PM
TAEGER LESLIE MSVP Chief Financial OfficerJan 04, 2017 Buy$0.0750,0003,50094,574Jan 06, 2017, 05:00 PM
MILLER LLOYD I III10% OwnerDec 16, 2016 Sale$0.0438,9671,5590Dec 19, 2016, 02:30 PM
MILLER LLOYD I III10% OwnerDec 15, 2016 Sale$0.0420,00080038,967Dec 16, 2016, 02:14 PM
MILLER LLOYD I III10% OwnerAug 12, 2016 Sale$0.0516,0008805,828,968Aug 15, 2016, 03:38 PM
MILLER LLOYD I III10% OwnerAug 01, 2016 Sale$0.0680,0004,8645,844,968Aug 02, 2016, 04:46 PM
MILLER LLOYD I III10% OwnerJun 08, 2016 Sale$0.0814,0001,1205,924,968Jun 09, 2016, 12:25 PM
BVF PARTNERS L P/IL10% OwnerJul 01, 2014 Option Exercise$0.30616,563184,9693,993,637Jul 03, 2014, 07:56 PM
HOLLIMAN JOHN M IIIExecutive ChairmanDec 06, 2013 Buy$0.2625,0006,500507,614Dec 06, 2013, 03:54 PM
MILLER LLOYD I III10% OwnerAug 07, 2013 Buy$0.2387,50019,7405,938,968Aug 09, 2013, 11:21 AM
MILLER LLOYD I III10% OwnerJul 30, 2013 Buy$0.201,139,000227,8005,851,468Aug 01, 2013, 02:54 PM
MILLER LLOYD I III10% OwnerJun 10, 2013 Buy$0.18300,00054,0004,712,468Jun 11, 2013, 02:39 PM
FELDMAN FREDRIC JDirectorApr 08, 2013 Buy$0.2125,0005,250225,564Apr 10, 2013, 01:15 PM
MILLER LLOYD I III10% OwnerDec 17, 2012 Buy$0.16175,00028,1224,412,468Dec 18, 2012, 03:47 PM
MILLER LLOYD I III10% OwnerDec 07, 2012 Buy$0.1697,25015,8234,237,468Dec 10, 2012, 12:44 PM
MILLER LLOYD I III10% OwnerDec 06, 2012 Buy$0.1619,7503,2494,140,218Dec 07, 2012, 12:50 PM
MILLER LLOYD I III10% OwnerJul 11, 2012 Buy$0.1863,00011,170374,817Nov 29, 2012, 04:37 PM
MILLER LLOYD I III10% OwnerSep 17, 2012 Buy$0.1430,1024,06457,327Nov 29, 2012, 04:37 PM
MILLER LLOYD I III10% OwnerJul 06, 2012 Buy$0.168,7501,400311,817Nov 29, 2012, 04:37 PM
MILLER LLOYD I III10% OwnerSep 14, 2012 Buy$0.1427,2253,67527,225Nov 29, 2012, 04:37 PM
MILLER LLOYD I III10% OwnerJul 05, 2012 Buy$0.161,114178303,067Nov 29, 2012, 04:37 PM
MILLER LLOYD I III10% OwnerJul 23, 2012 Buy$0.1735,9176,138472,792Nov 29, 2012, 04:37 PM
MILLER LLOYD I III10% OwnerJul 18, 2012 Buy$0.1722,0003,850436,875Nov 29, 2012, 04:37 PM
MILLER LLOYD I III10% OwnerJul 16, 2012 Buy$0.1823,0584,150414,875Nov 29, 2012, 04:37 PM
MILLER LLOYD I III10% OwnerJul 13, 2012 Buy$0.1817,0003,060391,817Nov 29, 2012, 04:37 PM
MILLER LLOYD I III10% OwnerSep 19, 2012 Buy$0.1433,0174,45790,344Nov 29, 2012, 04:37 PM
MILLER LLOYD I III10% OwnerJun 27, 2012 Buy$0.1619,7473,160252,498Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerSep 12, 2012 Buy$0.144,6566293,752,268Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerNov 26, 2012 Buy$0.14100,00014,1004,120,468Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 11, 2012 Buy$0.1512,1271,819186,602Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerSep 10, 2012 Buy$0.14913,747,612Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 25, 2012 Buy$0.1618,7503,000232,751Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerNov 23, 2012 Buy$0.141,0001414,020,468Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 08, 2012 Buy$0.1510,4761,571174,475Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerSep 07, 2012 Buy$0.1415,0142,0283,747,603Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 22, 2012 Buy$0.1611,0021,760214,001Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerNov 21, 2012 Buy$0.14107,50015,1584,019,468Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 07, 2012 Buy$0.1572,00010,800163,999Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerSep 06, 2012 Buy$0.142,5003383,732,589Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 21, 2012 Buy$0.1650080202,999Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerOct 19, 2012 Buy$0.1425,0003,5003,911,968Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJul 03, 2012 Buy$0.1623,7503,800301,953Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 06, 2012 Buy$0.1789,79914,81791,999Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerSep 05, 2012 Buy$0.14104143,730,089Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 19, 2012 Buy$0.165,000800202,499Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerOct 15, 2012 Buy$0.1495,00013,1103,886,968Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJul 02, 2012 Buy$0.163,960634278,203Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerOct 03, 2012 Buy$0.1334,7004,5113,791,968Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 05, 2012 Buy$0.171,0001652,200Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerAug 30, 2012 Buy$0.1574,08211,1123,729,985Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 18, 2012 Buy$0.165,500880197,499Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 29, 2012 Buy$0.1621,7453,479274,243Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerSep 13, 2012 Buy$0.145,0006753,757,268Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 04, 2012 Buy$0.171,2001981,200Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerAug 29, 2012 Buy$0.1525,7543,8633,655,903Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerJun 12, 2012 Buy$0.155,397810191,999Nov 29, 2012, 04:33 PM
MILLER LLOYD I III10% OwnerMay 22, 2012 Buy$0.1717,5002,8882,811,180Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 20, 2012 Buy$0.1619,4583,0353,549,443Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerJul 26, 2012 Buy$0.169,6361,5512,857,207Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 28, 2012 Buy$0.15164253,630,149Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 03, 2012 Buy$0.163,5535763,131,466Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerMay 21, 2012 Buy$0.176,5001,0732,793,680Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 17, 2012 Buy$0.1666,00010,6263,529,985Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerJul 25, 2012 Buy$0.1617,2502,7772,847,571Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 27, 2012 Buy$0.1617,2762,6953,629,985Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 02, 2012 Buy$0.165,7009233,127,913Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerMay 17, 2012 Buy$0.1730,9555,1082,787,180Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 15, 2012 Buy$0.1620,0003,2203,463,985Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerJul 24, 2012 Buy$0.169,0001,4492,830,321Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 24, 2012 Buy$0.1619,3813,0233,612,709Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 01, 2012 Buy$0.16208,60033,5853,122,213Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerMay 16, 2012 Buy$0.1754,1408,9332,756,225Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 14, 2012 Buy$0.16100,61716,1993,443,985Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerMay 31, 2012 Buy$0.171,5002482,821,321Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 23, 2012 Buy$0.164,6007183,593,328Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerJul 31, 2012 Buy$0.1631,7685,1152,913,613Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerMay 14, 2012 Buy$0.1710,0001,6502,702,085Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 13, 2012 Buy$0.16113,38318,2553,343,368Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerMay 30, 2012 Buy$0.176,5011,0732,819,821Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 22, 2012 Buy$0.1619,2313,0003,588,728Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerJul 30, 2012 Buy$0.1614,1182,2732,881,845Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 07, 2012 Buy$0.1795,00015,6753,229,985Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerMay 23, 2012 Buy$0.172,1403532,813,320Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 21, 2012 Buy$0.1620,0543,1283,569,497Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerJul 27, 2012 Buy$0.1610,5201,6942,867,727Nov 29, 2012, 04:29 PM
MILLER LLOYD I III10% OwnerAug 06, 2012 Buy$0.173,5195813,134,985Nov 29, 2012, 04:29 PM
HOLLIMAN JOHN M IIIExecutive ChairmanOct 19, 2012 Buy$0.1450,0007,000482,614Oct 19, 2012, 05:15 PM
HOLLIMAN JOHN M IIIExecutive ChairmanOct 18, 2012 Buy$0.14100,00014,000432,614Oct 19, 2012, 05:15 PM
BVF PARTNERS L P/IL10% OwnerSep 06, 2011 Buy$0.26312,90081,0414,610,200Sep 08, 2011, 04:26 PM
BVF PARTNERS L P/IL10% OwnerAug 22, 2011 Buy$0.268,8002,2884,410,600Aug 22, 2011, 06:04 PM
BVF PARTNERS L P/IL10% OwnerAug 19, 2011 Buy$0.2638,90010,1144,404,900Aug 22, 2011, 06:04 PM
BVF PARTNERS L P/IL10% OwnerAug 18, 2011 Buy$0.2631,2008,1124,377,100Aug 22, 2011, 06:04 PM
BVF PARTNERS L P/IL10% OwnerJul 29, 2011 Buy$0.25931,200232,8004,345,900Aug 01, 2011, 06:17 PM
BVF PARTNERS L P/IL10% OwnerJul 28, 2011 Buy$0.2523,0505,7633,747,400Aug 01, 2011, 06:17 PM
BVF PARTNERS L P/IL10% OwnerJul 26, 2011 Buy$0.2518,4004,6003,730,300Jul 28, 2011, 04:26 PM
BVF PARTNERS L P/IL10% OwnerJul 20, 2011 Buy$0.25252,60063,0993,716,400Jul 22, 2011, 04:38 PM
BVF PARTNERS L P/IL10% OwnerJul 18, 2011 Buy$0.25338,90084,4203,522,300Jul 18, 2011, 06:11 PM
BVF PARTNERS L P/IL10% OwnerJul 14, 2011 Buy$0.2519,7004,9253,212,300Jul 18, 2011, 06:11 PM
BVF INVESTMENTS LLCSee Explanation of ResponsesJul 11, 2011 Buy$0.259,0002,2503,192,600Jul 13, 2011, 06:01 PM
BVF PARTNERS L P/IL10% OwnerJun 30, 2011 Buy$0.254,7001,1723,183,600Jul 05, 2011, 04:50 PM
BVF PARTNERS L P/IL10% OwnerJun 28, 2011 Buy$0.2530,4007,6003,173,650Jun 29, 2011, 06:55 PM
BVF PARTNERS L P/IL10% OwnerJun 27, 2011 Buy$0.2556,70014,1753,155,200Jun 29, 2011, 06:55 PM
BVF PARTNERS L P/IL10% OwnerJun 29, 2011 Buy$0.2512,9503,2153,180,750Jun 29, 2011, 06:55 PM
WARDELL WILLIAM MDirectorJan 14, 2011 Buy$0.644,3002,752150,702Jan 14, 2011, 12:10 PM
WARDELL WILLIAM MDirectorJan 12, 2011 Buy$0.562,7001,512146,402Jan 13, 2011, 05:45 PM
WARDELL WILLIAM MDirectorJan 11, 2011 Buy$0.5926,50015,635143,702Jan 13, 2011, 05:45 PM
FELDMAN FREDRIC JDirectorJan 06, 2011 Buy$0.5913,0007,670190,564Jan 07, 2011, 04:00 PM
WHITE AUGUSTUS ADirectorJan 03, 2011 Buy$0.5810,3456,000179,031Jan 04, 2011, 01:34 PM
WHITE AUGUSTUS ADirectorDec 28, 2010 Buy$0.5614,4148,072168,686Dec 29, 2010, 04:21 PM
WHITE AUGUSTUS ADirectorDec 23, 2010 Buy$0.5716,7719,559154,272Dec 28, 2010, 11:26 AM
HOWSE ELWOOD DDirectorDec 22, 2010 Buy$0.4950,00024,500212,703Dec 23, 2010, 10:56 AM
HOLLIMAN JOHN M IIIExecutive ChairmanDec 21, 2010 Buy$0.4525,00011,250272,614Dec 21, 2010, 03:22 PM
HOLLIMAN JOHN M IIIExecutive ChairmanDec 20, 2010 Buy$0.4725,00011,750247,614Dec 21, 2010, 03:22 PM
Load More Insider Transactions
Buy Sale Option Exercise
OwnerRelationshipDateValue($)
SUBIN NEIL S10% Owner12/21/20185,356
SUBIN NEIL S10% Owner12/21/201810,712
MILLER LLOYD I III10% Owner10/05/20176,000
BVF PARTNERS L P/ILSee Explanation of Responses07/14/201714,534
BVF PARTNERS L P/ILSee Explanation of Responses07/14/2017239,618
BVF PARTNERS L P/ILSee Explanation of Responses07/14/20176,343
TAEGER LESLIE MSVP Chief Financial Officer01/04/20173,500
MILLER LLOYD I III10% Owner12/16/20161,559
MILLER LLOYD I III10% Owner12/15/2016800
MILLER LLOYD I III10% Owner08/12/2016880
MILLER LLOYD I III10% Owner08/01/20164,864
MILLER LLOYD I III10% Owner06/08/20161,120
BVF PARTNERS L P/IL10% Owner07/01/2014184,969
HOLLIMAN JOHN M IIIExecutive Chairman12/06/20136,500
MILLER LLOYD I III10% Owner08/07/201319,740
MILLER LLOYD I III10% Owner07/30/2013227,800
MILLER LLOYD I III10% Owner06/10/201354,000
FELDMAN FREDRIC JDirector04/08/20135,250
MILLER LLOYD I III10% Owner12/17/201228,122
MILLER LLOYD I III10% Owner12/07/201215,823
MILLER LLOYD I III10% Owner12/06/20123,249
MILLER LLOYD I III10% Owner07/11/201211,170
MILLER LLOYD I III10% Owner09/17/20124,064
MILLER LLOYD I III10% Owner07/06/20121,400
MILLER LLOYD I III10% Owner09/14/20123,675
MILLER LLOYD I III10% Owner07/05/2012178
MILLER LLOYD I III10% Owner07/23/20126,138
MILLER LLOYD I III10% Owner07/18/20123,850
MILLER LLOYD I III10% Owner07/16/20124,150
MILLER LLOYD I III10% Owner07/13/20123,060
MILLER LLOYD I III10% Owner09/19/20124,457
MILLER LLOYD I III10% Owner06/27/20123,160
MILLER LLOYD I III10% Owner09/12/2012629
MILLER LLOYD I III10% Owner11/26/201214,100
MILLER LLOYD I III10% Owner06/11/20121,819
MILLER LLOYD I III10% Owner09/10/20121
MILLER LLOYD I III10% Owner06/25/20123,000
MILLER LLOYD I III10% Owner11/23/2012141
MILLER LLOYD I III10% Owner06/08/20121,571
MILLER LLOYD I III10% Owner09/07/20122,028
MILLER LLOYD I III10% Owner06/22/20121,760
MILLER LLOYD I III10% Owner11/21/201215,158
MILLER LLOYD I III10% Owner06/07/201210,800
MILLER LLOYD I III10% Owner09/06/2012338
MILLER LLOYD I III10% Owner06/21/201280
MILLER LLOYD I III10% Owner10/19/20123,500
MILLER LLOYD I III10% Owner07/03/20123,800
MILLER LLOYD I III10% Owner06/06/201214,817
MILLER LLOYD I III10% Owner09/05/201214
MILLER LLOYD I III10% Owner06/19/2012800
MILLER LLOYD I III10% Owner10/15/201213,110
MILLER LLOYD I III10% Owner07/02/2012634
MILLER LLOYD I III10% Owner10/03/20124,511
MILLER LLOYD I III10% Owner06/05/2012165
MILLER LLOYD I III10% Owner08/30/201211,112
MILLER LLOYD I III10% Owner06/18/2012880
MILLER LLOYD I III10% Owner06/29/20123,479
MILLER LLOYD I III10% Owner09/13/2012675
MILLER LLOYD I III10% Owner06/04/2012198
MILLER LLOYD I III10% Owner08/29/20123,863
MILLER LLOYD I III10% Owner06/12/2012810
MILLER LLOYD I III10% Owner05/22/20122,888
MILLER LLOYD I III10% Owner08/20/20123,035
MILLER LLOYD I III10% Owner07/26/20121,551
MILLER LLOYD I III10% Owner08/28/201225
MILLER LLOYD I III10% Owner08/03/2012576
MILLER LLOYD I III10% Owner05/21/20121,073
MILLER LLOYD I III10% Owner08/17/201210,626
MILLER LLOYD I III10% Owner07/25/20122,777
MILLER LLOYD I III10% Owner08/27/20122,695
MILLER LLOYD I III10% Owner08/02/2012923
MILLER LLOYD I III10% Owner05/17/20125,108
MILLER LLOYD I III10% Owner08/15/20123,220
MILLER LLOYD I III10% Owner07/24/20121,449
MILLER LLOYD I III10% Owner08/24/20123,023
MILLER LLOYD I III10% Owner08/01/201233,585
MILLER LLOYD I III10% Owner05/16/20128,933
MILLER LLOYD I III10% Owner08/14/201216,199
MILLER LLOYD I III10% Owner05/31/2012248
MILLER LLOYD I III10% Owner08/23/2012718
MILLER LLOYD I III10% Owner07/31/20125,115
MILLER LLOYD I III10% Owner05/14/20121,650
MILLER LLOYD I III10% Owner08/13/201218,255
MILLER LLOYD I III10% Owner05/30/20121,073
MILLER LLOYD I III10% Owner08/22/20123,000
MILLER LLOYD I III10% Owner07/30/20122,273
MILLER LLOYD I III10% Owner08/07/201215,675
MILLER LLOYD I III10% Owner05/23/2012353
MILLER LLOYD I III10% Owner08/21/20123,128
MILLER LLOYD I III10% Owner07/27/20121,694
MILLER LLOYD I III10% Owner08/06/2012581
HOLLIMAN JOHN M IIIExecutive Chairman10/19/20127,000
HOLLIMAN JOHN M IIIExecutive Chairman10/18/201214,000
BVF PARTNERS L P/IL10% Owner09/06/201181,041
BVF PARTNERS L P/IL10% Owner08/22/20112,288
BVF PARTNERS L P/IL10% Owner08/19/201110,114
BVF PARTNERS L P/IL10% Owner08/18/20118,112
BVF PARTNERS L P/IL10% Owner07/29/2011232,800
BVF PARTNERS L P/IL10% Owner07/28/20115,763
BVF PARTNERS L P/IL10% Owner07/26/20114,600
BVF PARTNERS L P/IL10% Owner07/20/201163,099
BVF PARTNERS L P/IL10% Owner07/18/201184,420
BVF PARTNERS L P/IL10% Owner07/14/20114,925
BVF INVESTMENTS LLCSee Explanation of Responses07/11/20112,250
BVF PARTNERS L P/IL10% Owner06/30/20111,172
BVF PARTNERS L P/IL10% Owner06/28/20117,600
BVF PARTNERS L P/IL10% Owner06/27/201114,175
BVF PARTNERS L P/IL10% Owner06/29/20113,215
WARDELL WILLIAM MDirector01/14/20112,752
WARDELL WILLIAM MDirector01/12/20111,512
WARDELL WILLIAM MDirector01/11/201115,635
FELDMAN FREDRIC JDirector01/06/20117,670
WHITE AUGUSTUS ADirector01/03/20116,000
WHITE AUGUSTUS ADirector12/28/20108,072
WHITE AUGUSTUS ADirector12/23/20109,559
HOWSE ELWOOD DDirector12/22/201024,500
HOLLIMAN JOHN M IIIExecutive Chairman12/21/201011,250
HOLLIMAN JOHN M IIIExecutive Chairman12/20/201011,750
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