Bluebird bio Inc. (BLUE) NASDAQ
$3.04 (0.16) (-5.00%)
Market Cap: $325.14M
As of 09/22/23 04:00 PM EDT. Market closed.
Bluebird bio Inc. (BLUE)
NASDAQ
$3.04
(0.16) (-5.00%)
Market Cap: $325.14M
As of 09/22/23 04:00 PM EDT. Market closed.
we are leading the gene therapy revolution. our integrated product platforms encompass gene therapy, cancer immunotherapy and gene editing – providing us with the potential to treat, and hopefully cure, a broad range of serious diseases. we have a lot of energy, and it’s not just the abundance of coffee that keeps us going. find out what sparks our excitement and inspires us every ... read more
we are leading the gene therapy revolution. our integrated product platforms encompass gene therapy, cancer immunotherapy and gene editing – providing us with the potential to treat, and hopefully cure, a broad range of serious diseases. we have a lot of energy, and it’s not just the abundance of coffee that keeps us going. find out what sparks our excitement and inspires us every day. read less
COMPANY PROFILE
Sector
Manufacturing
Industry
Biological Product (except Diagnostic) Manufacturing
CEO Compensation (Base)
$610,000
CEO Compensation (Total)
$23.96M
Sector
Manufacturing
Industry
Biological Product (except Diagnostic) Manufacturing
Full Time Employees
733
CEO Compensation (Base)
$610,000
CEO Compensation (Total)
$23.96M
Address
.
PRICE CHART FOR BLUEBIRD BIO INC
From:
To:
NEWS
INSIDEARBITRAGE ARTICLES
KEY STATS
Open
-
Previous Close
$3.20
Days Range
$3.04 - $3.23
52 week range
$2.78 - $8.58
Volume
2,226
Avg. Volume (30 days)
3,345,785
Market Cap
$325.14M
Dividend Yield
-
P/E
(3.39)
Shares Outstanding
106,952,739
Open
-
Previous Close
$3.20
Days Range
$3.04 - $3.23
52 week range
$2.78 - $8.58
Volume
2,226
Avg. Volume (30 days)
3,345,785
Market Cap
$325.14M
Dividend Yield
-
P/E
(3.39)
Shares Outstanding
106,952,739
FINANCIAL STATEMENTS FOR BLUEBIRD BIO INC
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INSIDER TRANSACTIONS FOR BLUEBIRD BIO INC
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| Klima Thomas J | See Remarks | Sep 05, 2023 | Sale | $3.79 | 922 | 3,493 | 132,127 | Sep 06, 2023, 04:30 PM |
| Obenshain Andrew | President and CEO | Aug 10, 2023 | Sale | $3.54 | 16,929 | 59,956 | 291,941 | Aug 10, 2023, 05:00 PM |
| Klima Thomas J | See Remarks | Jun 02, 2023 | Sale | $3.50 | 4,130 | 14,451 | 133,049 | Jun 06, 2023, 04:06 PM |
| Leiderman Elisabeth | Director | Oct 17, 2022 | Sale | $6.46 | 1,004 | 6,490 | 11,466 | Mar 09, 2023, 04:06 PM |
| Klima Thomas J | See Remarks | Feb 01, 2023 | Option Exercise | $6.38 | 2,260 | 14,419 | 82,179 | Feb 03, 2023, 04:06 PM |
| Colvin Richard A | Chief Medical Officer | Feb 01, 2023 | Option Exercise | $6.38 | 1,153 | 7,356 | 73,078 | Feb 03, 2023, 04:05 PM |
| Obenshain Andrew | President and CEO | Feb 01, 2023 | Option Exercise | $6.38 | 1,420 | 9,060 | 241,270 | Feb 03, 2023, 04:05 PM |
| Obenshain Andrew | President and CEO | Jan 11, 2023 | Sale | $7.80 | 3,178 | 24,802 | 242,690 | Jan 13, 2023, 04:19 PM |
| Colvin Richard A | Chief Medical Officer | Jan 11, 2023 | Sale | $7.80 | 557 | 4,347 | 74,231 | Jan 13, 2023, 04:19 PM |
| Leschly Nick | Director | Jan 11, 2023 | Sale | $7.80 | 4,290 | 33,480 | 280,149 | Jan 13, 2023, 04:19 PM |
| Colvin Richard A | Chief Medical Officer | Nov 04, 2022 | Sale | $6.41 | 218 | 1,398 | 74,788 | Nov 08, 2022, 05:46 PM |
| Obenshain Andrew | President and CEO | Nov 04, 2022 | Sale | $6.41 | 1,263 | 8,101 | 245,868 | Nov 08, 2022, 05:46 PM |
| Cole Jason | Chief Strategy & Financial Off | Aug 19, 2022 | Sale | $5.53 | 14,194 | 78,473 | 189,546 | Aug 23, 2022, 04:50 PM |
| Cole Jason | Chief Strategy & Financial Off | Aug 04, 2022 | Sale | $4.39 | 7,448 | 32,707 | 203,740 | Aug 08, 2022, 04:16 PM |
| Obenshain Andrew | President and CEO | Aug 04, 2022 | Sale | $4.39 | 21,805 | 95,754 | 247,131 | Aug 08, 2022, 04:16 PM |
| Eggimann Anne-Virginie | Chief Regulatory Officer | Jul 12, 2022 | Sale | $4.95 | 1,358 | 6,722 | 42,252 | Jul 14, 2022, 04:15 PM |
| Klima Thomas J | Chief Commercial Officer | Jun 03, 2022 | Sale | $3.07 | 3,753 | 11,535 | 71,439 | Jun 07, 2022, 04:16 PM |
| Whitten Jessica | Chief Accounting Officer | Jan 11, 2022 | Sale | $9.64 | 279 | 2,690 | 49,413 | Jan 12, 2022, 09:16 PM |
| Whitten Jessica | Chief Accounting Officer | Jan 10, 2022 | Sale | $9.40 | 130 | 1,222 | 49,692 | Jan 12, 2022, 09:16 PM |
| Cole Jason | Chief Operating and | Jan 11, 2022 | Sale | $9.64 | 3,387 | 32,659 | 186,188 | Jan 12, 2022, 09:15 PM |
| Cole Jason | Chief Operating and | Jan 10, 2022 | Sale | $9.40 | 1,584 | 14,893 | 189,575 | Jan 12, 2022, 09:15 PM |
| Leschly Nick | Director | Jan 11, 2022 | Sale | $9.64 | 5,068 | 48,869 | 281,330 | Jan 12, 2022, 09:15 PM |
| Leschly Nick | Director | Jan 10, 2022 | Sale | $9.40 | 2,369 | 22,274 | 286,398 | Jan 12, 2022, 09:15 PM |
| Obenshain Andrew | President and CEO | Jan 11, 2022 | Sale | $9.64 | 4,683 | 45,156 | 246,696 | Jan 12, 2022, 09:15 PM |
| Obenshain Andrew | President and CEO | Jan 10, 2022 | Sale | $9.36 | 3,042 | 28,467 | 253,569 | Jan 12, 2022, 09:15 PM |
| Whitten Jessica | Chief Accounting Officer | Jan 05, 2022 | Sale | $10.44 | 2,984 | 31,143 | 49,822 | Jan 07, 2022, 04:28 PM |
| Obenshain Andrew | President and CEO | Dec 07, 2021 | Sale | $10.18 | 832 | 8,469 | 254,421 | Dec 09, 2021, 04:51 PM |
| Obenshain Andrew | President of SGD | Apr 05, 2021 | Sale | $30.21 | 29 | 876 | 40,137 | Apr 07, 2021, 04:43 PM |
| Gregory Philip D | Chief Scientific Officer | Apr 05, 2021 | Sale | $30.21 | 39 | 1,178 | 46,868 | Apr 07, 2021, 04:43 PM |
| Cole Jason | Chief Operating and | Apr 05, 2021 | Sale | $30.21 | 37 | 1,118 | 47,960 | Apr 07, 2021, 04:42 PM |
| Leschly Nick | President and CEO | Mar 04, 2021 | Option Exercise | $5.50 | 203,355 | 1,118,534 | 307,580 | Mar 08, 2021, 04:50 PM |
| Leschly Nick | President and CEO | Mar 02, 2021 | Sale | $29.58 | 444 | 13,134 | 104,225 | Mar 04, 2021, 04:46 PM |
| Obenshain Andrew | President of SGD | Mar 02, 2021 | Sale | $29.58 | 34 | 1,006 | 40,166 | Mar 04, 2021, 04:46 PM |
| Davidson David | Chief Medical Officer | Mar 02, 2021 | Sale | $29.58 | 42 | 1,242 | 47,829 | Mar 04, 2021, 04:46 PM |
| Cole Jason | Chief Operating and | Mar 02, 2021 | Sale | $29.58 | 38 | 1,124 | 47,997 | Mar 04, 2021, 04:46 PM |
| Gregory Philip D | Chief Scientific Officer | Mar 02, 2021 | Sale | $29.58 | 39 | 1,154 | 46,907 | Mar 04, 2021, 04:46 PM |
| Baird William D III | Chief Financial Officer | Feb 17, 2021 | Sale | $28.16 | 693 | 19,516 | 35,529 | Feb 18, 2021, 05:22 PM |
| Burnett Katy | Principal Accounting Officer | Feb 17, 2021 | Sale | $28.16 | 518 | 14,588 | 4,097 | Feb 18, 2021, 05:22 PM |
| Gregory Philip D | Chief Scientific Officer | Feb 17, 2021 | Sale | $28.16 | 664 | 18,699 | 46,946 | Feb 18, 2021, 05:22 PM |
| Obenshain Andrew | President of SGD | Feb 17, 2021 | Sale | $28.16 | 749 | 21,093 | 40,200 | Feb 18, 2021, 05:22 PM |
| Davidson David | Chief Medical Officer | Feb 17, 2021 | Sale | $28.16 | 698 | 19,657 | 47,871 | Feb 18, 2021, 05:22 PM |
| Cole Jason | Chief Operating and | Feb 17, 2021 | Sale | $28.16 | 665 | 18,727 | 48,035 | Feb 18, 2021, 05:22 PM |
| Baird William D III | Chief Financial Officer | Feb 12, 2021 | Sale | $45.52 | 1,216 | 55,352 | 21,581 | Feb 17, 2021, 05:23 PM |
| Obenshain Andrew | President of SGD | Feb 02, 2021 | Sale | $45.93 | 34 | 1,561 | 23,884 | Feb 04, 2021, 04:04 PM |
| Davidson David | Chief Medical Officer | Feb 02, 2021 | Sale | $45.93 | 63 | 2,893 | 36,298 | Feb 04, 2021, 04:04 PM |
| Leschly Nick | President and CEO | Feb 02, 2021 | Sale | $45.93 | 594 | 27,280 | 86,669 | Feb 04, 2021, 04:04 PM |
| Cole Jason | Chief Operating and | Feb 02, 2021 | Sale | $45.93 | 38 | 1,745 | 32,785 | Feb 04, 2021, 04:03 PM |
| Gregory Philip D | Chief Scientific Officer | Feb 02, 2021 | Sale | $45.93 | 59 | 2,710 | 32,948 | Feb 04, 2021, 04:03 PM |
| Leschly Nick | President and CEO | Jan 06, 2021 | Sale | $45.05 | 10,095 | 454,814 | 91,485 | Jan 08, 2021, 06:18 PM |
| Leschly Nick | President and CEO | Jan 05, 2021 | Sale | $44.95 | 333 | 14,969 | 97,358 | Jan 08, 2021, 06:18 PM |
| Baird William D III | Chief Financial Officer | Jan 06, 2021 | Sale | $45.05 | 949 | 42,756 | 23,194 | Jan 08, 2021, 05:57 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Jan 06, 2021 | Sale | $45.05 | 1,814 | 81,727 | 25,862 | Jan 08, 2021, 05:57 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Jan 05, 2021 | Sale | $44.95 | 40 | 1,798 | 26,917 | Jan 08, 2021, 05:57 PM |
| Davidson David | Chief Medical Officer | Jan 06, 2021 | Sale | $45.05 | 3,167 | 142,684 | 37,685 | Jan 08, 2021, 05:57 PM |
| Davidson David | Chief Medical Officer | Jan 05, 2021 | Sale | $44.95 | 48 | 2,158 | 39,528 | Jan 08, 2021, 05:57 PM |
| Cole Jason | Chief Operating and | Jan 06, 2021 | Sale | $45.05 | 2,358 | 106,236 | 33,809 | Jan 08, 2021, 05:56 PM |
| Cole Jason | Chief Operating and | Jan 05, 2021 | Sale | $44.95 | 43 | 1,933 | 35,181 | Jan 08, 2021, 05:56 PM |
| Smith-Farrell Joanne | COO, Oncology | Jan 06, 2021 | Sale | $45.05 | 1,287 | 57,984 | 21,147 | Jan 08, 2021, 05:56 PM |
| Smith-Farrell Joanne | COO, Oncology | Jan 05, 2021 | Sale | $44.95 | 42 | 1,888 | 21,896 | Jan 08, 2021, 05:56 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 06, 2021 | Sale | $45.05 | 2,754 | 124,077 | 34,159 | Jan 08, 2021, 05:56 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 05, 2021 | Sale | $44.95 | 45 | 2,023 | 35,761 | Jan 08, 2021, 05:56 PM |
| Burnett Katy | Principal Accounting Officer | Dec 03, 2020 | Sale | $46.09 | 123 | 5,669 | 1,460 | Dec 04, 2020, 04:49 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Dec 02, 2020 | Sale | $46.20 | 36 | 1,663 | 26,958 | Dec 04, 2020, 04:48 PM |
| Smith-Farrell Joanne | COO, Oncology | Dec 02, 2020 | Sale | $46.20 | 38 | 1,756 | 21,939 | Dec 04, 2020, 04:48 PM |
| Cole Jason | Chief Operating and | Dec 02, 2020 | Sale | $46.20 | 38 | 1,756 | 35,225 | Dec 04, 2020, 04:48 PM |
| Gregory Philip D | Chief Scientific Officer | Dec 02, 2020 | Sale | $46.20 | 59 | 2,726 | 35,808 | Dec 04, 2020, 04:48 PM |
| Davidson David | Chief Medical Officer | Dec 02, 2020 | Sale | $46.20 | 64 | 2,957 | 39,578 | Dec 04, 2020, 04:48 PM |
| Leschly Nick | President and CEO | Dec 02, 2020 | Sale | $46.20 | 444 | 20,512 | 97,705 | Dec 04, 2020, 04:48 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Nov 02, 2020 | Sale | $52.99 | 35 | 1,855 | 27,004 | Nov 04, 2020, 04:05 PM |
| Smith-Farrell Joanne | COO, Oncology | Nov 02, 2020 | Sale | $52.97 | 37 | 1,960 | 21,987 | Nov 04, 2020, 04:05 PM |
| Cole Jason | Chief Operating and | Nov 02, 2020 | Sale | $52.97 | 37 | 1,960 | 35,273 | Nov 04, 2020, 04:05 PM |
| Gregory Philip D | Chief Scientific Officer | Nov 02, 2020 | Sale | $52.93 | 59 | 3,123 | 35,881 | Nov 04, 2020, 04:05 PM |
| Davidson David | Chief Medical Officer | Nov 02, 2020 | Sale | $52.94 | 63 | 3,335 | 39,658 | Nov 04, 2020, 04:05 PM |
| Leschly Nick | President and CEO | Nov 02, 2020 | Sale | $52.94 | 444 | 23,506 | 98,260 | Nov 04, 2020, 04:04 PM |
| Davidson David | Chief Medical Officer | Oct 02, 2020 | Sale | $52.76 | 64 | 3,377 | 39,703 | Oct 06, 2020, 04:06 PM |
| Cole Jason | Chief Operating and | Oct 02, 2020 | Sale | $52.76 | 38 | 2,005 | 35,299 | Oct 06, 2020, 04:06 PM |
| Smith-Farrell Joanne | Chief Business Officer | Oct 02, 2020 | Sale | $52.76 | 38 | 2,005 | 22,013 | Oct 06, 2020, 04:06 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Oct 02, 2020 | Sale | $52.76 | 36 | 1,900 | 27,028 | Oct 06, 2020, 04:05 PM |
| Leschly Nick | President and CEO | Oct 02, 2020 | Sale | $52.76 | 450 | 23,744 | 98,579 | Oct 06, 2020, 04:05 PM |
| Gregory Philip D | Chief Scientific Officer | Oct 02, 2020 | Sale | $52.76 | 60 | 3,166 | 35,924 | Oct 06, 2020, 04:05 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Sep 03, 2020 | Sale | $58.60 | 35 | 2,051 | 27,063 | Sep 08, 2020, 04:08 PM |
| Smith-Farrell Joanne | Chief Business Officer | Sep 03, 2020 | Sale | $58.60 | 36 | 2,110 | 22,051 | Sep 08, 2020, 04:08 PM |
| Cole Jason | Chief Operating and | Sep 03, 2020 | Sale | $58.60 | 36 | 2,110 | 35,337 | Sep 08, 2020, 04:08 PM |
| Gregory Philip D | Chief Scientific Officer | Sep 03, 2020 | Sale | $58.60 | 58 | 3,399 | 35,984 | Sep 08, 2020, 04:08 PM |
| Davidson David | Chief Medical Officer | Sep 03, 2020 | Sale | $58.60 | 41 | 2,403 | 39,767 | Sep 08, 2020, 04:07 PM |
| Leschly Nick | President and CEO | Sep 03, 2020 | Sale | $58.60 | 431 | 25,257 | 99,029 | Sep 08, 2020, 04:07 PM |
| Smith-Farrell Joanne | Chief Business Officer | Aug 25, 2020 | Sale | $58.95 | 225 | 13,264 | 22,087 | Aug 27, 2020, 05:11 PM |
| WENTWORTH KORY JAMES | Principal Accounting Officer | Aug 03, 2020 | Sale | $61.00 | 82 | 5,002 | 9,512 | Aug 05, 2020, 04:06 PM |
| Davidson David | Chief Medical Officer | Aug 03, 2020 | Sale | $60.75 | 42 | 2,552 | 39,819 | Aug 05, 2020, 04:06 PM |
| Leschly Nick | President and CEO | Aug 03, 2020 | Sale | $60.49 | 444 | 26,856 | 99,572 | Aug 05, 2020, 04:05 PM |
| Cole Jason | Chief Operating and | Aug 03, 2020 | Sale | $60.48 | 37 | 2,238 | 35,382 | Aug 05, 2020, 04:05 PM |
| Smith-Farrell Joanne | Chief Business Officer | Aug 03, 2020 | Sale | $60.48 | 37 | 2,238 | 22,321 | Aug 05, 2020, 04:05 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Aug 03, 2020 | Sale | $60.49 | 35 | 2,117 | 27,107 | Aug 05, 2020, 04:05 PM |
| Gregory Philip D | Chief Scientific Officer | Aug 03, 2020 | Sale | $60.49 | 59 | 3,569 | 36,057 | Aug 05, 2020, 04:05 PM |
| WENTWORTH KORY JAMES | Principal Accounting Officer | Jul 20, 2020 | Sale | $66.38 | 596 | 39,562 | 9,594 | Jul 22, 2020, 05:22 PM |
| Davidson David | Chief Medical Officer | Jul 02, 2020 | Sale | $61.57 | 42 | 2,586 | 39,850 | Jul 07, 2020, 05:22 PM |
| Leschly Nick | President and CEO | Jul 02, 2020 | Sale | $61.57 | 443 | 27,277 | 99,904 | Jul 07, 2020, 05:19 PM |
| Cole Jason | Chief Operating and | Jul 02, 2020 | Sale | $61.57 | 38 | 2,340 | 35,410 | Jul 07, 2020, 05:18 PM |
| Smith-Farrell Joanne | Chief Business Officer | Jul 02, 2020 | Sale | $61.57 | 38 | 2,340 | 22,349 | Jul 07, 2020, 05:17 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Jul 02, 2020 | Sale | $61.57 | 36 | 2,217 | 27,133 | Jul 07, 2020, 05:16 PM |
| Gregory Philip D | Chief Scientific Officer | Jul 02, 2020 | Sale | $61.57 | 59 | 3,633 | 36,101 | Jul 07, 2020, 05:15 PM |
| WENTWORTH KORY JAMES | Principal Accounting Officer | Jun 04, 2020 | Sale | $65.23 | 154 | 10,045 | 10,252 | Jun 08, 2020, 04:24 PM |
| Smith-Farrell Joanne | Chief Business Officer | Jun 04, 2020 | Sale | $65.23 | 170 | 11,089 | 22,456 | Jun 08, 2020, 04:24 PM |
| Smith-Farrell Joanne | Chief Business Officer | Jun 02, 2020 | Sale | $64.03 | 37 | 2,369 | 22,585 | Jun 04, 2020, 05:44 PM |
| Cole Jason | Chief Operating and | Jun 02, 2020 | Sale | $64.03 | 38 | 2,433 | 35,477 | Jun 04, 2020, 05:44 PM |
| Davidson David | Chief Medical Officer | Jun 02, 2020 | Sale | $64.03 | 42 | 2,689 | 39,924 | Jun 04, 2020, 05:44 PM |
| Leschly Nick | President and CEO | Jun 02, 2020 | Sale | $64.04 | 444 | 28,433 | 100,688 | Jun 04, 2020, 05:44 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Jun 02, 2020 | Sale | $64.04 | 35 | 2,241 | 27,196 | Jun 04, 2020, 05:44 PM |
| Gregory Philip D | Chief Scientific Officer | Jun 02, 2020 | Sale | $64.03 | 59 | 3,778 | 36,205 | Jun 04, 2020, 05:43 PM |
| Smith-Farrell Joanne | Chief Business Officer | May 04, 2020 | Sale | $50.17 | 232 | 11,639 | 22,654 | May 05, 2020, 04:05 PM |
| Smith-Farrell Joanne | Chief Business Officer | Apr 06, 2020 | Sale | $43.73 | 583 | 25,495 | 21,393 | Apr 08, 2020, 04:12 PM |
| Baird William D III | Chief Financial Officer | Feb 13, 2020 | Sale | $90.60 | 1,254 | 113,612 | 13,746 | Feb 18, 2020, 07:14 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 10, 2020 | Option Exercise | $50.51 | 600 | 30,306 | 25,308 | Jan 14, 2020, 05:33 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 10, 2020 | Sale | $94.03 | 600 | 56,416 | 24,708 | Jan 14, 2020, 05:33 PM |
| Smith-Farrell Joanne | Chief Business Officer | Jan 07, 2020 | Sale | $89.97 | 408 | 36,708 | 11,976 | Jan 09, 2020, 05:33 PM |
| WENTWORTH KORY JAMES | Principal Accounting Officer | Jan 07, 2020 | Sale | $89.97 | 223 | 20,064 | 6,308 | Jan 09, 2020, 05:33 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Jan 07, 2020 | Sale | $89.97 | 1,049 | 94,380 | 18,148 | Jan 09, 2020, 05:33 PM |
| Cole Jason | Chief Operating and | Jan 07, 2020 | Sale | $89.97 | 1,957 | 176,074 | 25,049 | Jan 09, 2020, 05:33 PM |
| Davidson David | Chief Medical Officer | Jan 07, 2020 | Sale | $89.97 | 3,297 | 296,635 | 28,319 | Jan 09, 2020, 05:33 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 07, 2020 | Sale | $89.97 | 4,134 | 371,941 | 24,708 | Jan 09, 2020, 05:33 PM |
| Leschly Nick | President and CEO | Jan 07, 2020 | Sale | $89.97 | 10,163 | 914,377 | 56,712 | Jan 09, 2020, 05:33 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 06, 2020 | Sale | $86.66 | 250 | 21,665 | 28,842 | Jan 08, 2020, 05:13 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Jan 03, 2020 | Sale | $84.96 | 517 | 43,924 | 19,197 | Jan 07, 2020, 05:02 PM |
| WENTWORTH KORY JAMES | Principal Accounting Officer | Dec 19, 2019 | Sale | $92.59 | 397 | 36,758 | 6,449 | Dec 23, 2019, 05:00 PM |
| Gregory Philip D | Chief Scientific Officer | Dec 17, 2019 | Option Exercise | $50.51 | 1,800 | 90,918 | 30,892 | Dec 19, 2019, 04:54 PM |
| Gregory Philip D | Chief Scientific Officer | Dec 17, 2019 | Sale | $94.31 | 1,800 | 169,749 | 29,092 | Dec 19, 2019, 04:54 PM |
| Gregory Philip D | Chief Scientific Officer | Dec 05, 2019 | Sale | $80.57 | 250 | 20,142 | 29,092 | Dec 09, 2019, 05:01 PM |
| Gregory Philip D | Chief Scientific Officer | Nov 05, 2019 | Sale | $81.95 | 250 | 20,488 | 29,342 | Nov 07, 2019, 04:11 PM |
| Gregory Philip D | Chief Scientific Officer | Oct 07, 2019 | Sale | $89.07 | 250 | 22,267 | 29,592 | Oct 09, 2019, 04:14 PM |
| Davidson David | Chief Medical Officer | Sep 09, 2019 | Option Exercise | $50.51 | 3,000 | 151,530 | 34,616 | Sep 11, 2019, 04:29 PM |
| Davidson David | Chief Medical Officer | Sep 10, 2019 | Option Exercise | $50.51 | 2,060 | 104,051 | 33,676 | Sep 11, 2019, 04:29 PM |
| Davidson David | Chief Medical Officer | Sep 09, 2019 | Sale | $100.11 | 3,000 | 300,339 | 31,616 | Sep 11, 2019, 04:29 PM |
| Davidson David | Chief Medical Officer | Sep 10, 2019 | Sale | $100.16 | 2,060 | 206,323 | 31,616 | Sep 11, 2019, 04:29 PM |
| Gregory Philip D | Chief Scientific Officer | Sep 05, 2019 | Option Exercise | $50.51 | 600 | 30,306 | 30,692 | Sep 09, 2019, 04:54 PM |
| Gregory Philip D | Chief Scientific Officer | Sep 05, 2019 | Sale | $101.20 | 850 | 86,018 | 29,842 | Sep 09, 2019, 04:54 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | Aug 20, 2019 | Option Exercise | $24.47 | 500 | 12,235 | 41,421 | Aug 21, 2019, 04:06 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | Aug 20, 2019 | Sale | $124.00 | 500 | 62,000 | 40,921 | Aug 21, 2019, 04:06 PM |
| Gregory Philip D | Chief Scientific Officer | Aug 08, 2019 | Option Exercise | $75.60 | 700 | 52,920 | 31,042 | Aug 12, 2019, 04:08 PM |
| Gregory Philip D | Chief Scientific Officer | Aug 08, 2019 | Sale | $124.03 | 950 | 117,824 | 30,092 | Aug 12, 2019, 04:08 PM |
| Davidson David | Chief Medical Officer | Aug 06, 2019 | Option Exercise | $50.51 | 5,060 | 255,581 | 36,676 | Aug 08, 2019, 04:19 PM |
| Davidson David | Chief Medical Officer | Aug 06, 2019 | Sale | $116.08 | 5,060 | 587,388 | 33,716 | Aug 08, 2019, 04:19 PM |
| Gregory Philip D | Chief Scientific Officer | Aug 05, 2019 | Option Exercise | $50.51 | 600 | 30,306 | 31,192 | Aug 07, 2019, 04:14 PM |
| Gregory Philip D | Chief Scientific Officer | Aug 05, 2019 | Sale | $116.93 | 850 | 99,393 | 30,442 | Aug 07, 2019, 04:14 PM |
| Gregory Philip D | Chief Scientific Officer | Jul 05, 2019 | Option Exercise | $64.02 | 1,300 | 83,226 | 32,392 | Jul 09, 2019, 04:22 PM |
| Gregory Philip D | Chief Scientific Officer | Jul 05, 2019 | Sale | $129.13 | 1,800 | 232,427 | 31,303 | Jul 09, 2019, 04:22 PM |
| Davidson David | Chief Medical Officer | Jul 05, 2019 | Option Exercise | $48.57 | 7,660 | 372,053 | 39,276 | Jul 09, 2019, 04:20 PM |
| Davidson David | Chief Medical Officer | Jul 05, 2019 | Sale | $129.47 | 7,660 | 991,746 | 36,448 | Jul 09, 2019, 04:20 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | Jun 18, 2019 | Option Exercise | $24.47 | 100 | 2,447 | 41,021 | Jun 20, 2019, 04:52 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | Jun 18, 2019 | Sale | $126.12 | 100 | 12,612 | 40,921 | Jun 20, 2019, 04:52 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | Jun 10, 2019 | Option Exercise | $24.47 | 1,400 | 34,258 | 42,321 | Jun 12, 2019, 04:31 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | Jun 10, 2019 | Sale | $125.44 | 1,400 | 175,619 | 41,121 | Jun 12, 2019, 04:31 PM |
| Davidson David | Chief Medical Officer | Jun 06, 2019 | Option Exercise | $50.51 | 5,060 | 255,581 | 36,676 | Jun 10, 2019, 04:14 PM |
| Davidson David | Chief Medical Officer | Jun 06, 2019 | Sale | $122.64 | 5,060 | 620,539 | 34,460 | Jun 10, 2019, 04:14 PM |
| WENTWORTH KORY JAMES | Principal Accounting Officer | Jun 05, 2019 | Sale | $127.60 | 61 | 7,784 | 6,880 | Jun 07, 2019, 04:11 PM |
| Gregory Philip D | Chief Scientific Officer | Jun 05, 2019 | Option Exercise | $64.02 | 1,300 | 83,226 | 32,892 | Jun 07, 2019, 04:09 PM |
| Gregory Philip D | Chief Scientific Officer | Jun 05, 2019 | Sale | $128.60 | 1,800 | 231,489 | 31,893 | Jun 07, 2019, 04:09 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | May 10, 2019 | Option Exercise | $24.47 | 1,500 | 36,705 | 42,421 | May 14, 2019, 04:08 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | May 10, 2019 | Sale | $132.30 | 1,500 | 198,451 | 42,221 | May 14, 2019, 04:08 PM |
| Cole Jason | Chief Operating and | May 10, 2019 | Option Exercise | $50.51 | 562 | 28,387 | 27,006 | May 14, 2019, 04:07 PM |
| Gregory Philip D | Chief Scientific Officer | May 06, 2019 | Option Exercise | $64.02 | 1,300 | 83,226 | 33,392 | May 08, 2019, 04:35 PM |
| Gregory Philip D | Chief Scientific Officer | May 06, 2019 | Sale | $138.44 | 1,800 | 249,184 | 32,192 | May 08, 2019, 04:35 PM |
| Davidson David | Chief Medical Officer | May 06, 2019 | Option Exercise | $5.50 | 6,360 | 34,983 | 37,976 | May 08, 2019, 04:35 PM |
| Davidson David | Chief Medical Officer | May 06, 2019 | Sale | $138.95 | 6,360 | 883,718 | 35,276 | May 08, 2019, 04:35 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | Apr 10, 2019 | Option Exercise | $24.47 | 1,500 | 36,705 | 42,421 | Apr 12, 2019, 04:17 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | Apr 10, 2019 | Sale | $156.65 | 1,500 | 234,976 | 41,321 | Apr 12, 2019, 04:17 PM |
| Gregory Philip D | Chief Scientific Officer | Apr 05, 2019 | Option Exercise | $64.02 | 1,300 | 83,226 | 33,892 | Apr 09, 2019, 04:50 PM |
| Gregory Philip D | Chief Scientific Officer | Apr 05, 2019 | Sale | $157.60 | 1,800 | 283,682 | 33,092 | Apr 09, 2019, 04:50 PM |
| Davidson David | Chief Medical Officer | Apr 04, 2019 | Option Exercise | $5.50 | 6,360 | 34,983 | 37,976 | Apr 08, 2019, 04:11 PM |
| Davidson David | Chief Medical Officer | Apr 04, 2019 | Sale | $160.06 | 6,360 | 1,017,976 | 35,353 | Apr 08, 2019, 04:11 PM |
| Davidson David | Chief Medical Officer | Mar 13, 2019 | Option Exercise | $5.50 | 3,101 | 17,057 | 34,717 | Mar 15, 2019, 04:32 PM |
| Davidson David | Chief Medical Officer | Mar 13, 2019 | Sale | $146.41 | 3,101 | 454,004 | 33,017 | Mar 15, 2019, 04:32 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | Mar 11, 2019 | Option Exercise | $24.47 | 1,500 | 36,705 | 42,421 | Mar 13, 2019, 04:14 PM |
| Walsh Jeffrey T. | Chief Strategy Officer | Mar 11, 2019 | Sale | $139.80 | 1,500 | 209,698 | 40,921 | Mar 13, 2019, 04:14 PM |
| Gregory Philip D | Chief Scientific Officer | Mar 05, 2019 | Option Exercise | $64.02 | 1,300 | 83,226 | 34,392 | Mar 07, 2019, 04:26 PM |
| Gregory Philip D | Chief Scientific Officer | Mar 05, 2019 | Sale | $147.71 | 1,800 | 265,879 | 33,792 | Mar 07, 2019, 04:26 PM |
| Davidson David | Chief Medical Officer | Mar 04, 2019 | Option Exercise | $50.51 | 4,910 | 248,004 | 36,526 | Mar 06, 2019, 04:32 PM |
| Davidson David | Chief Medical Officer | Mar 04, 2019 | Sale | $155.77 | 4,910 | 764,833 | 34,579 | Mar 06, 2019, 04:32 PM |
| WENTWORTH KORY JAMES | Principal Accounting Officer | Feb 28, 2019 | Sale | $151.71 | 51 | 7,737 | 6,695 | Mar 04, 2019, 04:34 PM |
| Cole Jason | Chief Operating and | Feb 25, 2019 | Option Exercise | $40.44 | 6,248 | 252,687 | 32,692 | Feb 27, 2019, 04:59 PM |
| Cole Jason | Chief Operating and | Feb 25, 2019 | Sale | $150.24 | 6,248 | 938,697 | 26,969 | Feb 27, 2019, 04:59 PM |
| WENTWORTH KORY JAMES | Principal Accounting Officer | Feb 25, 2019 | Sale | $150.00 | 208 | 31,201 | 6,746 | Feb 27, 2019, 04:57 PM |
| Walsh Jeffrey T. | Chief Financial and | Feb 08, 2019 | Option Exercise | $24.47 | 1,500 | 36,705 | 42,421 | Feb 12, 2019, 04:11 PM |
| Walsh Jeffrey T. | Chief Financial and | Feb 08, 2019 | Sale | $131.29 | 1,500 | 196,928 | 41,421 | Feb 12, 2019, 04:11 PM |
| Gregory Philip D | Chief Scientific Officer | Feb 05, 2019 | Option Exercise | $64.02 | 1,300 | 83,226 | 34,892 | Feb 07, 2019, 05:21 PM |
| Gregory Philip D | Chief Scientific Officer | Feb 05, 2019 | Sale | $137.99 | 1,800 | 248,383 | 34,292 | Feb 07, 2019, 05:21 PM |
| Davidson David | Chief Medical Officer | Feb 04, 2019 | Option Exercise | $31.66 | 4,910 | 155,432 | 36,526 | Feb 05, 2019, 05:58 PM |
| Davidson David | Chief Medical Officer | Feb 04, 2019 | Sale | $134.30 | 4,910 | 659,416 | 35,926 | Feb 05, 2019, 05:58 PM |
| WENTWORTH KORY JAMES | Principal Accounting Officer | Jan 28, 2019 | Sale | $125.96 | 209 | 26,326 | 4,403 | Jan 30, 2019, 04:35 PM |
| Davidson David | Chief Medical Officer | Jan 18, 2019 | Option Exercise | $24.47 | 2,035 | 49,796 | 24,276 | Jan 23, 2019, 04:18 PM |
| Davidson David | Chief Medical Officer | Jan 18, 2019 | Sale | $130.05 | 2,035 | 264,644 | 22,241 | Jan 23, 2019, 04:18 PM |
| Walsh Jeffrey T. | Chief Financial | Jan 16, 2019 | Option Exercise | $24.47 | 3,000 | 73,410 | 35,483 | Jan 18, 2019, 04:06 PM |
| Walsh Jeffrey T. | Chief Financial | Jan 16, 2019 | Sale | $125.14 | 3,000 | 375,429 | 32,483 | Jan 18, 2019, 04:06 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 16, 2019 | Option Exercise | $75.60 | 1,400 | 105,840 | 28,742 | Jan 18, 2019, 04:03 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 16, 2019 | Sale | $124.25 | 1,900 | 236,069 | 26,842 | Jan 18, 2019, 04:03 PM |
| Walsh Jeffrey T. | Chief Financial | Jan 07, 2019 | Sale | $113.64 | 3,012 | 342,277 | 33,516 | Jan 09, 2019, 05:05 PM |
| Leschly Nick | President and CEO | Jan 07, 2019 | Sale | $113.64 | 7,374 | 837,965 | 195,732 | Jan 09, 2019, 05:03 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 07, 2019 | Option Exercise | $50.51 | 600 | 30,306 | 31,221 | Jan 09, 2019, 04:57 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 07, 2019 | Sale | $112.49 | 3,879 | 436,363 | 31,208 | Jan 09, 2019, 04:57 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Jan 07, 2019 | Sale | $113.64 | 643 | 73,068 | 14,767 | Jan 09, 2019, 04:53 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Jan 03, 2019 | Sale | $99.31 | 476 | 47,273 | 15,547 | Jan 09, 2019, 04:48 PM |
| Davidson David | Chief Medical Officer | Jan 07, 2019 | Sale | $113.64 | 2,664 | 302,733 | 23,157 | Jan 09, 2019, 04:46 PM |
| Cole Jason | Chief Legal Officer | Jan 07, 2019 | Sale | $113.64 | 1,416 | 160,914 | 20,682 | Jan 09, 2019, 04:39 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Jan 03, 2019 | Sale | $99.31 | 428 | 42,506 | 15,559 | Jan 07, 2019, 04:39 PM |
| Davidson David | Chief Medical Officer | Jan 03, 2019 | Option Exercise | $24.47 | 100 | 2,447 | 25,005 | Jan 04, 2019, 12:00 AM |
| Davidson David | Chief Medical Officer | Jan 02, 2019 | Option Exercise | $17.39 | 7,500 | 130,410 | 29,605 | Jan 04, 2019, 12:00 AM |
| Davidson David | Chief Medical Officer | Jan 03, 2019 | Sale | $100.32 | 100 | 10,032 | 24,905 | Jan 04, 2019, 12:00 AM |
| Davidson David | Chief Medical Officer | Jan 02, 2019 | Sale | $98.80 | 7,500 | 741,027 | 26,105 | Jan 04, 2019, 12:00 AM |
| WENTWORTH KORY JAMES | Principal Accounting Officer | Dec 19, 2018 | Sale | $103.05 | 388 | 39,983 | 4,612 | Dec 21, 2018, 04:26 PM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Dec 06, 2018 | Option Exercise | $68.65 | 15 | 1,030 | 15,625 | Dec 21, 2018, 04:11 PM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Dec 06, 2018 | Sale | $105.71 | 1,875 | 198,198 | 15,150 | Dec 21, 2018, 04:11 PM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Dec 06, 2018 | Sale | $105.71 | 1,875 | 198,198 | 15,135 | Dec 10, 2018, 04:11 PM |
| Gregory Philip D | Chief Scientific Officer | Dec 06, 2018 | Option Exercise | $50.51 | 600 | 30,306 | 31,471 | Dec 10, 2018, 04:09 PM |
| Gregory Philip D | Chief Scientific Officer | Dec 06, 2018 | Sale | $106.56 | 850 | 90,577 | 30,671 | Dec 10, 2018, 04:09 PM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Dec 03, 2018 | Sale | $113.83 | 1,890 | 215,135 | 15,610 | Dec 06, 2018, 04:14 PM |
| Davidson David | Chief Medical Officer | Dec 04, 2018 | Option Exercise | $5.50 | 2,000 | 11,001 | 26,905 | Dec 06, 2018, 04:12 PM |
| Davidson David | Chief Medical Officer | Dec 03, 2018 | Option Exercise | $5.50 | 6,000 | 33,002 | 30,905 | Dec 06, 2018, 04:12 PM |
| Davidson David | Chief Medical Officer | Dec 03, 2018 | Sale | $113.59 | 6,000 | 681,540 | 24,905 | Dec 06, 2018, 04:12 PM |
| Davidson David | Chief Medical Officer | Dec 04, 2018 | Sale | $121.05 | 2,000 | 242,108 | 26,005 | Dec 06, 2018, 04:12 PM |
| Walsh Jeffrey T. | Chief Financial | Nov 09, 2018 | Option Exercise | $24.47 | 1,500 | 36,705 | 36,995 | Nov 14, 2018, 04:10 PM |
| Walsh Jeffrey T. | Chief Financial | Nov 09, 2018 | Sale | $130.59 | 1,500 | 195,890 | 36,675 | Nov 14, 2018, 04:10 PM |
| Gregory Philip D | Chief Scientific Officer | Nov 05, 2018 | Option Exercise | $64.02 | 1,300 | 83,226 | 32,671 | Nov 07, 2018, 04:14 PM |
| Gregory Philip D | Chief Scientific Officer | Nov 05, 2018 | Sale | $137.38 | 1,800 | 247,277 | 32,071 | Nov 07, 2018, 04:14 PM |
| Davidson David | Chief Medical Officer | Nov 02, 2018 | Option Exercise | $5.50 | 5,000 | 27,502 | 29,905 | Nov 06, 2018, 04:15 PM |
| Davidson David | Chief Medical Officer | Nov 02, 2018 | Sale | $133.64 | 5,000 | 668,216 | 29,813 | Nov 06, 2018, 04:15 PM |
| Walsh Jeffrey T. | Chief Financial | Oct 10, 2018 | Option Exercise | $24.47 | 1,500 | 36,705 | 36,995 | Oct 12, 2018, 04:53 PM |
| Walsh Jeffrey T. | Chief Financial | Oct 10, 2018 | Sale | $135.23 | 1,500 | 202,839 | 35,895 | Oct 12, 2018, 04:53 PM |
| Gregory Philip D | Chief Scientific Officer | Oct 05, 2018 | Option Exercise | $64.02 | 1,300 | 83,226 | 33,171 | Oct 10, 2018, 04:17 PM |
| Gregory Philip D | Chief Scientific Officer | Oct 05, 2018 | Sale | $140.56 | 1,800 | 253,001 | 32,781 | Oct 10, 2018, 04:17 PM |
| Davidson David | Chief Medical Officer | Oct 02, 2018 | Option Exercise | $5.50 | 5,000 | 27,502 | 29,905 | Oct 04, 2018, 04:21 PM |
| Davidson David | Chief Medical Officer | Oct 02, 2018 | Sale | $139.32 | 5,000 | 696,588 | 25,353 | Oct 04, 2018, 04:21 PM |
| Walsh Jeffrey T. | Chief Financial | Sep 10, 2018 | Option Exercise | $24.47 | 1,500 | 36,705 | 36,995 | Sep 12, 2018, 12:00 AM |
| Mandell James | Director | Sep 10, 2018 | Sale | $150.77 | 1,000 | 150,771 | 1,568 | Sep 12, 2018, 12:00 AM |
| Walsh Jeffrey T. | Chief Financial | Sep 10, 2018 | Sale | $150.16 | 1,500 | 225,243 | 36,494 | Sep 12, 2018, 12:00 AM |
| Gregory Philip D | Chief Scientific Officer | Sep 05, 2018 | Option Exercise | $64.02 | 1,300 | 83,226 | 33,671 | Sep 07, 2018, 04:32 PM |
| Gregory Philip D | Chief Scientific Officer | Sep 05, 2018 | Sale | $163.02 | 1,800 | 293,441 | 32,894 | Sep 07, 2018, 04:32 PM |
| Davidson David | Chief Medical Officer | Sep 04, 2018 | Option Exercise | $5.50 | 7,000 | 38,503 | 31,905 | Sep 06, 2018, 04:12 PM |
| Davidson David | Chief Medical Officer | Sep 04, 2018 | Sale | $166.64 | 7,000 | 1,166,493 | 29,483 | Sep 06, 2018, 04:12 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 30, 2018 | Option Exercise | $10.88 | 20,000 | 217,689 | 55,495 | Sep 04, 2018, 05:03 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 30, 2018 | Sale | $175.40 | 20,000 | 3,507,948 | 36,473 | Sep 04, 2018, 05:03 PM |
| FINGER ALISON CECILY | Chief Commercial Officer | Aug 20, 2018 | Sale | $158.07 | 259 | 40,940 | 15,767 | Aug 22, 2018, 06:32 AM |
| Walsh Jeffrey T. | Chief Financial | Aug 10, 2018 | Option Exercise | $5.50 | 1,500 | 8,251 | 36,995 | Aug 14, 2018, 04:47 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 10, 2018 | Sale | $156.93 | 1,500 | 235,389 | 36,570 | Aug 14, 2018, 04:47 PM |
| Cole Jason | Chief Legal Officer | Aug 08, 2018 | Option Exercise | $22.53 | 4,438 | 99,988 | 21,610 | Aug 10, 2018, 06:48 AM |
| Gregory Philip D | Chief Scientific Officer | Aug 06, 2018 | Option Exercise | $64.02 | 1,300 | 83,226 | 34,171 | Aug 08, 2018, 04:06 PM |
| Gregory Philip D | Chief Scientific Officer | Aug 06, 2018 | Sale | $156.60 | 1,800 | 281,889 | 32,581 | Aug 08, 2018, 04:06 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 02, 2018 | Option Exercise | $5.50 | 21,500 | 118,259 | 56,995 | Aug 06, 2018, 04:10 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 02, 2018 | Sale | $152.02 | 21,500 | 3,268,495 | 49,030 | Aug 06, 2018, 04:10 PM |
| Davidson David | Chief Medical Officer | Aug 02, 2018 | Option Exercise | $5.50 | 7,000 | 38,503 | 31,905 | Aug 06, 2018, 04:08 PM |
| Davidson David | Chief Medical Officer | Aug 02, 2018 | Sale | $150.37 | 7,000 | 1,052,583 | 26,115 | Aug 06, 2018, 04:08 PM |
| Gregory Philip D | Chief Scientific Officer | Jun 18, 2018 | Sale | $178.41 | 3,901 | 695,978 | 34,971 | Jul 13, 2018, 04:34 PM |
| Davidson David | Chief Medical Officer | Jul 11, 2018 | Option Exercise | $5.50 | 3,000 | 16,501 | 27,905 | Jul 13, 2018, 04:31 PM |
| Davidson David | Chief Medical Officer | Jul 11, 2018 | Sale | $180.15 | 3,000 | 540,444 | 24,905 | Jul 13, 2018, 04:31 PM |
| Cole Jason | Chief Legal Officer | Jul 09, 2018 | Sale | $170.25 | 5,126 | 872,715 | 21,698 | Jul 11, 2018, 04:10 PM |
| Davidson David | Chief Medical Officer | Jul 02, 2018 | Option Exercise | $5.50 | 10,000 | 55,004 | 34,905 | Jul 03, 2018, 12:00 AM |
| Davidson David | Chief Medical Officer | Jul 02, 2018 | Sale | $153.96 | 10,000 | 1,539,601 | 32,087 | Jul 03, 2018, 12:00 AM |
| Gregory Philip D | Chief Scientific Officer | Jun 18, 2018 | Sale | $178.41 | 3,901 | 695,978 | 27,471 | Jun 20, 2018, 04:29 PM |
| Vachon Mark | Director | Jun 14, 2018 | Sale | $189.99 | 1,000 | 189,992 | 300 | Jun 18, 2018, 04:43 PM |
| Vachon Mark | Director | Jun 04, 2018 | Option Exercise | $42.07 | 6,000 | 252,420 | 7,000 | Jun 06, 2018, 04:42 PM |
| Vachon Mark | Director | Jun 04, 2018 | Sale | $188.22 | 6,000 | 1,129,302 | 4,000 | Jun 06, 2018, 04:42 PM |
| Davidson David | Chief Medical Officer | Jun 04, 2018 | Option Exercise | $24.47 | 13,000 | 318,110 | 37,905 | Jun 06, 2018, 04:39 PM |
| Davidson David | Chief Medical Officer | Jun 04, 2018 | Sale | $187.84 | 13,000 | 2,441,965 | 32,205 | Jun 06, 2018, 04:39 PM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Jun 04, 2018 | Option Exercise | $68.65 | 3,500 | 240,275 | 21,000 | Jun 06, 2018, 04:36 PM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Jun 04, 2018 | Sale | $199.11 | 3,500 | 696,892 | 17,500 | Jun 06, 2018, 04:36 PM |
| Cole Jason | Chief Legal Officer | May 04, 2018 | Sale | $170.89 | 3,750 | 640,849 | 25,948 | May 08, 2018, 04:18 PM |
| Davidson David | Chief Medical Officer | May 02, 2018 | Option Exercise | $24.47 | 13,000 | 318,110 | 37,905 | May 04, 2018, 04:39 PM |
| Davidson David | Chief Medical Officer | May 02, 2018 | Sale | $177.52 | 13,000 | 2,307,697 | 36,805 | May 04, 2018, 04:39 PM |
| Davidson David | Chief Medical Officer | Apr 12, 2018 | Option Exercise | $24.47 | 3,000 | 73,410 | 27,905 | Apr 16, 2018, 04:48 PM |
| Davidson David | Chief Medical Officer | Apr 12, 2018 | Sale | $180.17 | 3,000 | 540,507 | 24,905 | Apr 16, 2018, 04:48 PM |
| Gregory Philip D | Chief Scientific Officer | Apr 02, 2018 | Option Exercise | $50.51 | 1,250 | 63,137 | 31,522 | Apr 04, 2018, 04:50 PM |
| Gregory Philip D | Chief Scientific Officer | Apr 02, 2018 | Sale | $168.71 | 2,250 | 379,608 | 30,272 | Apr 04, 2018, 04:50 PM |
| Davidson David | Chief Medical Officer | Apr 02, 2018 | Option Exercise | $24.47 | 22,000 | 538,340 | 46,905 | Apr 04, 2018, 04:47 PM |
| Davidson David | Chief Medical Officer | Apr 02, 2018 | Sale | $167.52 | 22,000 | 3,685,383 | 45,950 | Apr 04, 2018, 04:47 PM |
| Vachon Mark | Director | Mar 15, 2018 | Option Exercise | $30.47 | 6,000 | 182,820 | 7,000 | Mar 19, 2018, 04:06 PM |
| Vachon Mark | Director | Mar 15, 2018 | Sale | $214.37 | 6,000 | 1,286,249 | 6,000 | Mar 19, 2018, 04:06 PM |
| Davidson David | Chief Medical Officer | Mar 02, 2018 | Option Exercise | $5.50 | 4,000 | 22,002 | 28,905 | Mar 06, 2018, 04:29 PM |
| Davidson David | Chief Medical Officer | Mar 02, 2018 | Sale | $201.19 | 4,000 | 804,751 | 26,905 | Mar 06, 2018, 04:29 PM |
| Gregory Philip D | Chief Scientific Officer | Mar 01, 2018 | Option Exercise | $50.51 | 1,250 | 63,137 | 32,522 | Mar 05, 2018, 05:14 PM |
| Gregory Philip D | Chief Scientific Officer | Mar 01, 2018 | Sale | $200.00 | 2,250 | 449,996 | 32,322 | Mar 05, 2018, 05:14 PM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Feb 28, 2018 | Option Exercise | $68.65 | 1,044 | 71,671 | 18,544 | Mar 02, 2018, 12:00 AM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Feb 28, 2018 | Sale | $202.67 | 1,044 | 211,592 | 18,144 | Mar 02, 2018, 12:00 AM |
| Gregory Philip D | Chief Scientific Officer | Feb 01, 2018 | Option Exercise | $50.51 | 1,250 | 63,137 | 33,522 | Feb 05, 2018, 04:02 PM |
| Gregory Philip D | Chief Scientific Officer | Feb 01, 2018 | Sale | $204.90 | 2,250 | 461,020 | 33,221 | Feb 05, 2018, 04:02 PM |
| Davidson David | Chief Medical Officer | Feb 02, 2018 | Option Exercise | $5.50 | 4,000 | 22,002 | 28,905 | Feb 05, 2018, 04:01 PM |
| Davidson David | Chief Medical Officer | Feb 02, 2018 | Sale | $202.36 | 4,000 | 809,440 | 26,305 | Feb 05, 2018, 04:01 PM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Jan 30, 2018 | Option Exercise | $68.65 | 14,794 | 1,015,608 | 28,512 | Feb 01, 2018, 04:31 PM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Jan 30, 2018 | Sale | $195.91 | 17,262 | 3,381,791 | 27,712 | Feb 01, 2018, 04:31 PM |
| Cole Jason | Chief Legal Officer | Jan 30, 2018 | Option Exercise | $22.53 | 25,000 | 563,250 | 44,798 | Feb 01, 2018, 04:30 PM |
| Cole Jason | Chief Legal Officer | Jan 30, 2018 | Sale | $195.91 | 25,000 | 4,897,744 | 43,638 | Feb 01, 2018, 04:30 PM |
| Walsh Jeffrey T. | Chief Financial | Jan 05, 2018 | Sale | $173.38 | 3,060 | 530,530 | 24,646 | Jan 09, 2018, 04:07 PM |
| Leschly Nick | President and CEO | Jan 05, 2018 | Sale | $173.38 | 5,435 | 942,297 | 171,009 | Jan 09, 2018, 04:06 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 05, 2018 | Sale | $173.38 | 1,712 | 296,820 | 23,995 | Jan 09, 2018, 04:06 PM |
| Davidson David | Chief Medical Officer | Jan 08, 2018 | Option Exercise | $5.50 | 1,200 | 6,600 | 14,855 | Jan 09, 2018, 04:05 PM |
| Davidson David | Chief Medical Officer | Jan 08, 2018 | Sale | $174.07 | 1,200 | 208,883 | 14,655 | Jan 09, 2018, 04:05 PM |
| Davidson David | Chief Medical Officer | Jan 05, 2018 | Sale | $173.38 | 2,322 | 402,578 | 13,959 | Jan 09, 2018, 04:05 PM |
| Cole Jason | Chief Legal Officer | Jan 05, 2018 | Sale | $173.38 | 1,129 | 195,742 | 19,945 | Jan 09, 2018, 04:05 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 03, 2018 | Option Exercise | $50.51 | 1,250 | 63,137 | 27,734 | Jan 05, 2018, 04:11 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 03, 2018 | Sale | $180.69 | 2,250 | 406,550 | 26,426 | Jan 05, 2018, 04:11 PM |
| Davidson David | Chief Medical Officer | Jan 03, 2018 | Option Exercise | $5.50 | 6,000 | 33,002 | 21,977 | Jan 05, 2018, 04:10 PM |
| Davidson David | Chief Medical Officer | Jan 03, 2018 | Sale | $180.30 | 6,000 | 1,081,781 | 19,477 | Jan 05, 2018, 04:10 PM |
| Leschly Nick | President and CEO | Dec 13, 2017 | Option Exercise | $5.50 | 37,873 | 208,317 | 293,232 | Dec 15, 2017, 04:09 PM |
| Leschly Nick | President and CEO | Dec 13, 2017 | Sale | $184.08 | 117,500 | 21,629,112 | 278,285 | Dec 15, 2017, 04:09 PM |
| Vachon Mark | Director | Dec 11, 2017 | Option Exercise | $30.47 | 6,000 | 182,820 | 8,000 | Dec 13, 2017, 04:10 PM |
| Vachon Mark | Director | Dec 11, 2017 | Sale | $216.64 | 7,000 | 1,516,466 | 7,700 | Dec 13, 2017, 04:10 PM |
| Walsh Jeffrey T. | Chief Financial | Dec 11, 2017 | Option Exercise | $24.47 | 9,900 | 242,253 | 37,205 | Dec 13, 2017, 04:09 PM |
| Walsh Jeffrey T. | Chief Financial | Dec 11, 2017 | Sale | $216.54 | 9,900 | 2,143,785 | 35,906 | Dec 13, 2017, 04:09 PM |
| HIGH SUSANNA GATTI | Chief Operating Officer | Dec 01, 2017 | Sale | $172.15 | 1,282 | 220,696 | 13,718 | Dec 05, 2017, 04:09 PM |
| Gregory Philip D | Chief Scientific Officer | Dec 01, 2017 | Option Exercise | $50.51 | 1,250 | 63,137 | 28,734 | Dec 05, 2017, 04:08 PM |
| Gregory Philip D | Chief Scientific Officer | Dec 01, 2017 | Sale | $172.54 | 2,250 | 388,211 | 27,784 | Dec 05, 2017, 04:08 PM |
| Davidson David | Chief Medical Officer | Dec 01, 2017 | Option Exercise | $5.50 | 4,000 | 22,002 | 19,977 | Dec 05, 2017, 04:08 PM |
| Davidson David | Chief Medical Officer | Dec 01, 2017 | Sale | $172.42 | 4,000 | 689,680 | 18,112 | Dec 05, 2017, 04:08 PM |
| Walsh Jeffrey T. | Chief Financial | Nov 10, 2017 | Option Exercise | $19.99 | 9,900 | 197,870 | 37,205 | Nov 14, 2017, 04:02 PM |
| Walsh Jeffrey T. | Chief Financial | Nov 10, 2017 | Sale | $149.58 | 9,900 | 1,480,863 | 35,105 | Nov 14, 2017, 04:02 PM |
| Walsh Jeffrey T. | Chief Financial | Nov 01, 2017 | Option Exercise | $5.50 | 35,000 | 192,514 | 62,305 | Nov 03, 2017, 04:08 PM |
| Walsh Jeffrey T. | Chief Financial | Nov 01, 2017 | Sale | $151.38 | 35,000 | 5,298,331 | 51,530 | Nov 03, 2017, 04:08 PM |
| Leschly Nick | President and CEO | Nov 01, 2017 | Option Exercise | $5.50 | 2,127 | 11,699 | 257,486 | Nov 03, 2017, 04:08 PM |
| Leschly Nick | President and CEO | Nov 01, 2017 | Sale | $145.17 | 2,127 | 308,779 | 255,359 | Nov 03, 2017, 04:08 PM |
| Gregory Philip D | Chief Scientific Officer | Nov 01, 2017 | Option Exercise | $50.51 | 1,250 | 63,137 | 29,734 | Nov 03, 2017, 04:07 PM |
| Gregory Philip D | Chief Scientific Officer | Nov 01, 2017 | Sale | $144.31 | 2,250 | 324,690 | 27,984 | Nov 03, 2017, 04:07 PM |
| Davidson David | Chief Medical Officer | Nov 01, 2017 | Option Exercise | $5.50 | 4,000 | 22,002 | 19,977 | Nov 03, 2017, 04:06 PM |
| Davidson David | Chief Medical Officer | Nov 01, 2017 | Sale | $145.21 | 4,000 | 580,821 | 18,349 | Nov 03, 2017, 04:06 PM |
| Leschly Nick | President and CEO | Oct 23, 2017 | Sale | $145.26 | 3,700 | 537,455 | 255,359 | Oct 24, 2017, 04:17 PM |
| Leschly Nick | President and CEO | Oct 20, 2017 | Sale | $145.02 | 3,350 | 485,814 | 259,059 | Oct 24, 2017, 04:17 PM |
| Leschly Nick | President and CEO | Oct 17, 2017 | Sale | $145.05 | 10,823 | 1,569,844 | 262,409 | Oct 19, 2017, 04:13 PM |
| Walsh Jeffrey T. | Chief Financial | Oct 10, 2017 | Option Exercise | $5.50 | 4,900 | 26,952 | 32,205 | Oct 11, 2017, 04:37 PM |
| Walsh Jeffrey T. | Chief Financial | Oct 10, 2017 | Sale | $129.94 | 4,900 | 636,724 | 29,405 | Oct 11, 2017, 04:37 PM |
| Gregory Philip D | Chief Scientific Officer | Oct 02, 2017 | Option Exercise | $50.51 | 1,250 | 63,137 | 30,734 | Oct 04, 2017, 04:02 PM |
| Gregory Philip D | Chief Scientific Officer | Oct 02, 2017 | Sale | $131.82 | 2,250 | 296,603 | 28,534 | Oct 04, 2017, 04:02 PM |
| Davidson David | Chief Medical Officer | Oct 02, 2017 | Option Exercise | $5.50 | 4,000 | 22,002 | 19,977 | Oct 04, 2017, 04:02 PM |
| Davidson David | Chief Medical Officer | Oct 02, 2017 | Sale | $131.31 | 4,000 | 525,248 | 18,636 | Oct 04, 2017, 04:02 PM |
| MARAGANORE JOHN | Director | Sep 14, 2017 | Option Exercise | $2.09 | 18,868 | 39,434 | 24,711 | Sep 18, 2017, 04:09 PM |
| MARAGANORE JOHN | Director | Sep 14, 2017 | Sale | $131.21 | 18,868 | 2,475,724 | 6,443 | Sep 18, 2017, 04:09 PM |
| Vachon Mark | Director | Sep 12, 2017 | Option Exercise | $30.47 | 6,000 | 182,820 | 8,000 | Sep 14, 2017, 04:09 PM |
| Vachon Mark | Director | Sep 12, 2017 | Sale | $126.82 | 6,000 | 760,921 | 6,730 | Sep 14, 2017, 04:09 PM |
| Walsh Jeffrey T. | Chief Financial | Sep 11, 2017 | Option Exercise | $5.50 | 4,900 | 26,952 | 32,205 | Sep 13, 2017, 04:07 PM |
| Walsh Jeffrey T. | Chief Financial | Sep 11, 2017 | Sale | $125.73 | 4,900 | 616,065 | 28,723 | Sep 13, 2017, 04:07 PM |
| Gregory Philip D | Chief Scientific Officer | Sep 01, 2017 | Option Exercise | $50.51 | 1,250 | 63,137 | 31,734 | Sep 06, 2017, 04:06 PM |
| Gregory Philip D | Chief Scientific Officer | Sep 01, 2017 | Sale | $126.06 | 2,250 | 283,635 | 30,184 | Sep 06, 2017, 04:06 PM |
| Davidson David | Chief Medical Officer | Sep 01, 2017 | Option Exercise | $5.50 | 12,000 | 66,005 | 27,977 | Sep 06, 2017, 04:06 PM |
| Davidson David | Chief Medical Officer | Sep 01, 2017 | Sale | $129.08 | 12,000 | 1,548,901 | 25,677 | Sep 06, 2017, 04:06 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 31, 2017 | Option Exercise | $5.50 | 12,000 | 66,005 | 39,305 | Sep 05, 2017, 04:02 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 31, 2017 | Sale | $125.01 | 12,000 | 1,500,096 | 27,305 | Sep 05, 2017, 04:02 PM |
| Schenkein David P | Director | Aug 31, 2017 | Option Exercise | $8.16 | 2,000 | 16,312 | 5,176 | Sep 05, 2017, 04:02 PM |
| Schenkein David P | Director | Aug 31, 2017 | Sale | $115.07 | 2,000 | 230,146 | 3,176 | Sep 05, 2017, 04:02 PM |
| LYNCH DANIEL | Director | Aug 31, 2017 | Option Exercise | $5.50 | 500 | 2,750 | 3,300 | Sep 05, 2017, 04:01 PM |
| LYNCH DANIEL | Director | Aug 31, 2017 | Sale | $120.00 | 500 | 60,000 | 2,800 | Sep 05, 2017, 04:01 PM |
| Leschly Nick | President and CEO | Sep 01, 2017 | Option Exercise | $5.50 | 6,364 | 35,005 | 295,732 | Sep 05, 2017, 04:01 PM |
| Leschly Nick | President and CEO | Aug 31, 2017 | Sale | $115.09 | 24,333 | 2,800,461 | 289,368 | Sep 05, 2017, 04:01 PM |
| Leschly Nick | President and CEO | Sep 01, 2017 | Sale | $130.04 | 22,500 | 2,925,990 | 273,232 | Sep 05, 2017, 04:01 PM |
| Leschly Nick | President and CEO | Aug 30, 2017 | Sale | $115.18 | 25,667 | 2,956,299 | 313,701 | Aug 31, 2017, 04:16 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 28, 2017 | Option Exercise | $5.50 | 1,250 | 6,876 | 28,555 | Aug 30, 2017, 04:17 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 28, 2017 | Sale | $107.06 | 1,250 | 133,826 | 27,305 | Aug 30, 2017, 04:17 PM |
| MARAGANORE JOHN | Director | Aug 24, 2017 | Option Exercise | $2.09 | 13,839 | 28,924 | 19,682 | Aug 28, 2017, 04:17 PM |
| MARAGANORE JOHN | Director | Aug 02, 2017 | Sale | $96.74 | 2,754 | 266,425 | 5,843 | Aug 28, 2017, 04:17 PM |
| MARAGANORE JOHN | Director | Aug 24, 2017 | Sale | $95.81 | 11,085 | 1,062,108 | 14,982 | Aug 28, 2017, 04:17 PM |
| Mandell James | Director | Aug 14, 2017 | Sale | $95.95 | 1,000 | 95,950 | 1,000 | Aug 15, 2017, 04:05 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 10, 2017 | Option Exercise | $5.50 | 1,250 | 6,876 | 28,555 | Aug 14, 2017, 04:03 PM |
| Walsh Jeffrey T. | Chief Financial | Aug 10, 2017 | Sale | $95.41 | 1,250 | 119,265 | 27,305 | Aug 14, 2017, 04:03 PM |
| Gregory Philip D | Chief Scientific Officer | Aug 07, 2017 | Option Exercise | $50.51 | 500 | 25,255 | 31,234 | Aug 09, 2017, 04:01 PM |
| Gregory Philip D | Chief Scientific Officer | Aug 07, 2017 | Sale | $99.00 | 750 | 74,250 | 30,484 | Aug 09, 2017, 04:01 PM |
| Sullivan Eric | Principal Accounting Officer | Aug 04, 2017 | Option Exercise | $53.68 | 445 | 23,890 | 6,119 | Aug 07, 2017, 04:02 PM |
| Sullivan Eric | Principal Accounting Officer | Aug 03, 2017 | Option Exercise | $22.20 | 416 | 9,237 | 6,090 | Aug 07, 2017, 04:02 PM |
| Sullivan Eric | Principal Accounting Officer | Aug 04, 2017 | Sale | $95.21 | 445 | 42,370 | 5,674 | Aug 07, 2017, 04:02 PM |
| Sullivan Eric | Principal Accounting Officer | Aug 03, 2017 | Sale | $92.35 | 416 | 38,418 | 5,674 | Aug 07, 2017, 04:02 PM |
| Gregory Philip D | Chief Scientific Officer | Aug 01, 2017 | Option Exercise | $50.51 | 750 | 37,882 | 32,234 | Aug 03, 2017, 04:04 PM |
| Gregory Philip D | Chief Scientific Officer | Aug 01, 2017 | Sale | $93.08 | 1,500 | 139,620 | 31,334 | Aug 03, 2017, 04:04 PM |
| Davidson David | Chief Medical Officer | Aug 01, 2017 | Option Exercise | $2.09 | 3,000 | 6,270 | 18,977 | Aug 03, 2017, 04:04 PM |
| Davidson David | Chief Medical Officer | Aug 01, 2017 | Sale | $92.37 | 3,000 | 277,099 | 17,177 | Aug 03, 2017, 04:04 PM |
| Walsh Jeffrey T. | Chief Financial | Jul 10, 2017 | Option Exercise | $5.50 | 2,500 | 13,751 | 29,805 | Jul 12, 2017, 04:15 PM |
| Walsh Jeffrey T. | Chief Financial | Jul 10, 2017 | Sale | $99.89 | 2,500 | 249,724 | 27,362 | Jul 12, 2017, 04:15 PM |
| Davidson David | Chief Medical Officer | Jul 07, 2017 | Sale | $100.49 | 1,200 | 120,583 | 16,077 | Jul 11, 2017, 04:07 PM |
| Gregory Philip D | Chief Scientific Officer | Jul 06, 2017 | Option Exercise | $50.51 | 1,250 | 63,137 | 33,734 | Jul 10, 2017, 04:03 PM |
| Gregory Philip D | Chief Scientific Officer | Jul 06, 2017 | Sale | $103.83 | 2,250 | 233,615 | 31,484 | Jul 10, 2017, 04:03 PM |
| Cole Jason | Chief Legal Officer | Jul 06, 2017 | Option Exercise | $22.53 | 5,126 | 115,489 | 20,927 | Jul 07, 2017, 04:04 PM |
| Sullivan Eric | Principal Accounting Officer | Jul 05, 2017 | Option Exercise | $51.75 | 3,580 | 185,252 | 9,987 | Jul 07, 2017, 04:03 PM |
| Sullivan Eric | Principal Accounting Officer | Jul 05, 2017 | Sale | $107.28 | 4,313 | 462,708 | 6,407 | Jul 07, 2017, 04:03 PM |
| Davidson David | Chief Medical Officer | Jul 05, 2017 | Option Exercise | $2.09 | 5,000 | 10,450 | 22,177 | Jul 07, 2017, 04:03 PM |
| Davidson David | Chief Medical Officer | Jul 05, 2017 | Sale | $105.28 | 5,000 | 526,394 | 17,277 | Jul 07, 2017, 04:03 PM |
| Sullivan Eric | Principal Accounting Officer | Jun 29, 2017 | Option Exercise | $36.62 | 6,728 | 246,411 | 13,194 | Jun 30, 2017, 04:01 PM |
| Sullivan Eric | Principal Accounting Officer | Jun 29, 2017 | Sale | $108.96 | 6,787 | 739,527 | 9,901 | Jun 30, 2017, 04:01 PM |
| Leschly Nick | President and CEO | Jun 27, 2017 | Sale | $108.05 | 25,000 | 2,701,168 | 360,656 | Jun 29, 2017, 04:01 PM |
| LYNCH DANIEL | Director | Jun 23, 2017 | Option Exercise | $3.79 | 4,000 | 15,146 | 6,800 | Jun 27, 2017, 04:05 PM |
| LYNCH DANIEL | Director | Jun 23, 2017 | Sale | $109.09 | 4,000 | 436,363 | 4,600 | Jun 27, 2017, 04:05 PM |
| LYNCH DANIEL | Director | Jun 20, 2017 | Option Exercise | $2.09 | 2,500 | 5,216 | 5,300 | Jun 22, 2017, 04:04 PM |
| LYNCH DANIEL | Director | Jun 20, 2017 | Sale | $120.03 | 2,500 | 300,070 | 2,800 | Jun 22, 2017, 04:04 PM |
| Gregory Philip D | Chief Scientific Officer | Jun 16, 2017 | Sale | $109.28 | 3,295 | 360,084 | 33,334 | Jun 22, 2017, 04:03 PM |
| Walsh Jeffrey T. | Chief Financial | Jun 12, 2017 | Option Exercise | $2.09 | 2,500 | 5,216 | 29,805 | Jun 14, 2017, 04:18 PM |
| Walsh Jeffrey T. | Chief Financial | Jun 12, 2017 | Sale | $109.53 | 2,500 | 273,832 | 27,886 | Jun 14, 2017, 04:18 PM |
| LYNCH DANIEL | Director | Jun 08, 2017 | Option Exercise | $2.09 | 2,500 | 5,216 | 5,300 | Jun 12, 2017, 04:57 PM |
| LYNCH DANIEL | Director | Jun 08, 2017 | Sale | $110.19 | 2,500 | 275,487 | 2,800 | Jun 12, 2017, 04:57 PM |
| Walsh Jeffrey T. | Chief Financial | Jun 06, 2017 | Option Exercise | $2.09 | 2,500 | 5,216 | 29,805 | Jun 08, 2017, 04:21 PM |
| Walsh Jeffrey T. | Chief Financial | Jun 06, 2017 | Sale | $100.05 | 2,500 | 250,135 | 27,305 | Jun 08, 2017, 04:21 PM |
| LYNCH DANIEL | Director | Jun 06, 2017 | Option Exercise | $2.09 | 2,263 | 4,722 | 3,663 | Jun 08, 2017, 04:20 PM |
| LYNCH DANIEL | Director | Jun 06, 2017 | Sale | $100.14 | 2,263 | 226,621 | 1,400 | Jun 08, 2017, 04:20 PM |
| Gregory Philip D | Chief Scientific Officer | Jun 06, 2017 | Option Exercise | $50.51 | 1,000 | 50,510 | 37,279 | Jun 08, 2017, 04:20 PM |
| Gregory Philip D | Chief Scientific Officer | Jun 06, 2017 | Sale | $99.04 | 1,500 | 148,560 | 35,779 | Jun 08, 2017, 04:20 PM |
| Cole Jason | Chief Legal Officer | Jun 07, 2017 | Option Exercise | $50.51 | 435 | 21,972 | 16,236 | Jun 08, 2017, 04:19 PM |
| Cole Jason | Chief Legal Officer | Jun 06, 2017 | Option Exercise | $25.43 | 16,810 | 427,415 | 32,611 | Jun 08, 2017, 04:19 PM |
| Cole Jason | Chief Legal Officer | Jun 06, 2017 | Sale | $100.22 | 16,810 | 1,684,698 | 15,801 | Jun 08, 2017, 04:19 PM |
| Cole Jason | Chief Legal Officer | Jun 07, 2017 | Sale | $100.05 | 435 | 43,522 | 15,801 | Jun 08, 2017, 04:19 PM |
| LYNCH DANIEL | Director | Jun 05, 2017 | Option Exercise | $2.09 | 1,000 | 2,086 | 2,400 | Jun 07, 2017, 04:47 PM |
| LYNCH DANIEL | Director | Jun 05, 2017 | Sale | $90.00 | 1,000 | 90,002 | 1,400 | Jun 07, 2017, 04:47 PM |
| Davidson David | Chief Medical Officer | Jun 05, 2017 | Option Exercise | $2.09 | 1,000 | 2,090 | 18,177 | Jun 07, 2017, 04:46 PM |
| Davidson David | Chief Medical Officer | Jun 05, 2017 | Sale | $90.00 | 1,000 | 90,002 | 17,177 | Jun 07, 2017, 04:46 PM |
| Gregory Philip D | Chief Scientific Officer | Jun 01, 2017 | Option Exercise | $50.51 | 750 | 37,882 | 37,779 | Jun 05, 2017, 04:34 PM |
| Gregory Philip D | Chief Scientific Officer | Jun 01, 2017 | Sale | $75.62 | 1,500 | 113,430 | 36,679 | Jun 05, 2017, 04:34 PM |
| Davidson David | Chief Medical Officer | Jun 01, 2017 | Option Exercise | $2.09 | 2,000 | 4,180 | 19,177 | Jun 05, 2017, 04:33 PM |
| Davidson David | Chief Medical Officer | Jun 01, 2017 | Sale | $75.42 | 2,000 | 150,849 | 17,177 | Jun 05, 2017, 04:33 PM |
| LYNCH DANIEL | Director | May 25, 2017 | Option Exercise | $2.09 | 2,000 | 4,173 | 3,400 | May 30, 2017, 04:07 PM |
| LYNCH DANIEL | Director | May 25, 2017 | Sale | $80.00 | 2,000 | 160,001 | 2,400 | May 30, 2017, 04:07 PM |
| Walsh Jeffrey T. | Chief Financial | May 10, 2017 | Option Exercise | $5.50 | 1,250 | 6,876 | 28,555 | May 12, 2017, 04:20 PM |
| Walsh Jeffrey T. | Chief Financial | May 10, 2017 | Sale | $88.77 | 1,250 | 110,966 | 27,308 | May 12, 2017, 04:20 PM |
| Gregory Philip D | Chief Scientific Officer | May 01, 2017 | Option Exercise | $50.51 | 750 | 37,882 | 38,529 | May 03, 2017, 04:26 PM |
| Gregory Philip D | Chief Scientific Officer | May 01, 2017 | Sale | $88.07 | 1,500 | 132,109 | 37,479 | May 03, 2017, 04:26 PM |
| Davidson David | Chief Medical Officer | May 01, 2017 | Option Exercise | $2.09 | 3,000 | 6,270 | 20,177 | May 03, 2017, 04:24 PM |
| Davidson David | Chief Medical Officer | May 01, 2017 | Sale | $88.74 | 3,000 | 266,208 | 19,167 | May 03, 2017, 04:24 PM |
| LYNCH DANIEL | Director | Apr 27, 2017 | Option Exercise | $2.09 | 1,000 | 2,086 | 2,400 | May 01, 2017, 04:05 PM |
| LYNCH DANIEL | Director | Apr 27, 2017 | Sale | $90.01 | 1,000 | 90,010 | 1,400 | May 01, 2017, 04:05 PM |
| Cole Jason | Chief Legal Officer | Apr 26, 2017 | Option Exercise | $22.53 | 3,750 | 84,488 | 15,801 | Apr 28, 2017, 04:04 PM |
| LYNCH DANIEL | Director | Apr 25, 2017 | Option Exercise | $2.09 | 2,000 | 4,173 | 3,400 | Apr 27, 2017, 04:08 PM |
| LYNCH DANIEL | Director | Apr 25, 2017 | Sale | $86.75 | 2,000 | 173,500 | 1,400 | Apr 27, 2017, 04:08 PM |
| Walsh Jeffrey T. | Chief Financial | Apr 10, 2017 | Option Exercise | $5.50 | 1,250 | 6,876 | 28,555 | Apr 12, 2017, 04:12 PM |
| Walsh Jeffrey T. | Chief Financial | Apr 10, 2017 | Sale | $87.38 | 1,250 | 109,225 | 27,305 | Apr 12, 2017, 04:12 PM |
| Davidson David | Chief Medical Officer | Apr 03, 2017 | Option Exercise | $2.09 | 3,000 | 6,270 | 20,177 | Apr 05, 2017, 04:09 PM |
| Davidson David | Chief Medical Officer | Apr 03, 2017 | Sale | $90.89 | 3,000 | 272,683 | 17,277 | Apr 05, 2017, 04:09 PM |
| LYNCH DANIEL | Director | Mar 27, 2017 | Option Exercise | $2.09 | 1,000 | 2,086 | 2,400 | Mar 28, 2017, 04:20 PM |
| LYNCH DANIEL | Director | Mar 24, 2017 | Option Exercise | $2.09 | 2,000 | 4,173 | 3,400 | Mar 28, 2017, 04:20 PM |
| LYNCH DANIEL | Director | Mar 27, 2017 | Sale | $90.00 | 1,000 | 90,000 | 1,400 | Mar 28, 2017, 04:20 PM |
| LYNCH DANIEL | Director | Mar 24, 2017 | Sale | $87.18 | 2,000 | 174,357 | 1,700 | Mar 28, 2017, 04:20 PM |
| Walsh Jeffrey T. | Chief Financial | Mar 16, 2017 | Option Exercise | $2.35 | 3,543 | 8,312 | 30,848 | Mar 20, 2017, 04:06 PM |
| Walsh Jeffrey T. | Chief Financial | Mar 16, 2017 | Sale | $100.07 | 3,543 | 354,562 | 27,305 | Mar 20, 2017, 04:06 PM |
| Sullivan Eric | Principal Accounting Officer | Mar 16, 2017 | Sale | $99.00 | 411 | 40,689 | 6,466 | Mar 20, 2017, 04:06 PM |
| LYNCH DANIEL | Director | Mar 16, 2017 | Option Exercise | $2.09 | 237 | 494 | 1,637 | Mar 20, 2017, 04:05 PM |
| LYNCH DANIEL | Director | Mar 16, 2017 | Sale | $100.07 | 237 | 23,718 | 1,400 | Mar 20, 2017, 04:05 PM |
| Cole Jason | Chief Legal Officer | Mar 16, 2017 | Option Exercise | $22.53 | 4,930 | 111,073 | 16,981 | Mar 20, 2017, 04:05 PM |
| Cole Jason | Chief Legal Officer | Mar 16, 2017 | Sale | $100.07 | 4,930 | 493,365 | 12,051 | Mar 20, 2017, 04:05 PM |
| MARAGANORE JOHN | Director | Mar 03, 2017 | Option Exercise | $5.20 | 13,839 | 71,923 | 18,682 | Mar 06, 2017, 05:24 PM |
| MARAGANORE JOHN | Director | Mar 03, 2017 | Sale | $85.02 | 13,839 | 1,176,646 | 4,843 | Mar 06, 2017, 05:24 PM |
| Schenkein David P | Director | Mar 01, 2017 | Option Exercise | $8.16 | 5,000 | 40,779 | 7,176 | Mar 03, 2017, 04:21 PM |
| Schenkein David P | Director | Mar 01, 2017 | Sale | $89.53 | 5,000 | 447,632 | 2,176 | Mar 03, 2017, 04:21 PM |
| LYNCH DANIEL | Director | Mar 01, 2017 | Option Exercise | $2.09 | 2,000 | 4,173 | 3,400 | Mar 03, 2017, 04:20 PM |
| LYNCH DANIEL | Director | Mar 01, 2017 | Sale | $90.32 | 2,000 | 180,636 | 1,400 | Mar 03, 2017, 04:20 PM |
| Sullivan Eric | Principal Accounting Officer | Feb 28, 2017 | Sale | $89.00 | 285 | 25,365 | 6,877 | Mar 02, 2017, 04:29 PM |
| Mandell James | Director | Feb 15, 2017 | Option Exercise | $25.16 | 1,050 | 26,418 | 2,050 | Feb 17, 2017, 08:41 AM |
| Mandell James | Director | Feb 15, 2017 | Sale | $80.22 | 1,050 | 84,235 | 1,000 | Feb 17, 2017, 08:41 AM |
| LYNCH DANIEL | Director | Feb 15, 2017 | Option Exercise | $2.09 | 150 | 313 | 1,550 | Feb 17, 2017, 08:40 AM |
| LYNCH DANIEL | Director | Feb 15, 2017 | Sale | $80.22 | 150 | 12,034 | 1,400 | Feb 17, 2017, 08:40 AM |
| Cole Jason | Chief Legal Officer | Feb 15, 2017 | Sale | $80.22 | 666 | 53,429 | 12,051 | Feb 17, 2017, 08:39 AM |
| Mandell James | Director | Feb 14, 2017 | Option Exercise | $22.65 | 5,950 | 134,782 | 6,950 | Feb 16, 2017, 08:17 AM |
| Mandell James | Director | Feb 14, 2017 | Sale | $80.01 | 5,950 | 476,076 | 1,000 | Feb 16, 2017, 08:17 AM |
| LYNCH DANIEL | Director | Feb 14, 2017 | Option Exercise | $2.09 | 850 | 1,773 | 2,250 | Feb 16, 2017, 08:16 AM |
| LYNCH DANIEL | Director | Feb 14, 2017 | Sale | $80.01 | 850 | 68,011 | 1,400 | Feb 16, 2017, 08:16 AM |
| Cole Jason | Chief Legal Officer | Feb 14, 2017 | Sale | $80.01 | 3,772 | 301,808 | 12,717 | Feb 16, 2017, 08:15 AM |
| Davidson David | Chief Medical Officer | Feb 01, 2017 | Option Exercise | $2.09 | 2,000 | 4,180 | 19,177 | Feb 03, 2017, 04:30 PM |
| Davidson David | Chief Medical Officer | Feb 01, 2017 | Sale | $74.09 | 2,000 | 148,187 | 18,307 | Feb 03, 2017, 04:30 PM |
| Mandell James | Director | Jan 31, 2017 | Option Exercise | $21.43 | 8,000 | 171,440 | 9,000 | Feb 02, 2017, 04:03 PM |
| Mandell James | Director | Jan 31, 2017 | Sale | $75.04 | 8,000 | 600,322 | 1,000 | Feb 02, 2017, 04:03 PM |
| Mandell James | Director | Jan 27, 2017 | Option Exercise | $21.43 | 5,000 | 107,150 | 6,000 | Jan 31, 2017, 04:29 PM |
| Mandell James | Director | Jan 27, 2017 | Sale | $70.10 | 5,000 | 350,499 | 1,000 | Jan 31, 2017, 04:29 PM |
| LYNCH DANIEL | Director | Jan 27, 2017 | Option Exercise | $2.09 | 1,000 | 2,086 | 2,400 | Jan 31, 2017, 04:28 PM |
| LYNCH DANIEL | Director | Jan 27, 2017 | Sale | $70.09 | 1,000 | 70,092 | 1,400 | Jan 31, 2017, 04:28 PM |
| Davidson David | Chief Medical Officer | Jan 27, 2017 | Option Exercise | $2.09 | 6,000 | 12,540 | 14,677 | Jan 31, 2017, 04:28 PM |
| Davidson David | Chief Medical Officer | Jan 27, 2017 | Sale | $69.02 | 6,000 | 414,149 | 13,545 | Jan 31, 2017, 04:28 PM |
| Walsh Jeffrey T. | Chief Financial | Jan 05, 2017 | Sale | $67.10 | 1,295 | 86,894 | 12,705 | Jan 09, 2017, 04:08 PM |
| Sullivan Eric | Principal Accounting Officer | Jan 05, 2017 | Sale | $67.10 | 229 | 15,366 | 5,412 | Jan 09, 2017, 04:08 PM |
| Leschly Nick | President and CEO | Jan 05, 2017 | Sale | $67.10 | 2,024 | 135,810 | 346,346 | Jan 09, 2017, 04:07 PM |
| Gregory Philip D | Chief Scientific Officer | Jan 05, 2017 | Sale | $67.10 | 790 | 53,009 | 29,279 | Jan 09, 2017, 04:07 PM |
| Davidson David | Chief Medical Officer | Jan 05, 2017 | Sale | $67.10 | 923 | 61,933 | 8,677 | Jan 09, 2017, 04:06 PM |
| Cole Jason | Chief Legal Officer | Jan 05, 2017 | Sale | $67.10 | 549 | 36,838 | 9,389 | Jan 09, 2017, 04:06 PM |
| Sullivan Eric | Principal Accounting Officer | Oct 03, 2016 | Option Exercise | $22.20 | 416 | 9,237 | 6,057 | Oct 05, 2016, 04:04 PM |
| Sullivan Eric | Principal Accounting Officer | Oct 03, 2016 | Sale | $67.00 | 416 | 27,871 | 5,641 | Oct 05, 2016, 04:04 PM |
| Sullivan Eric | Principal Accounting Officer | Sep 13, 2016 | Option Exercise | $22.20 | 416 | 9,237 | 6,057 | Sep 15, 2016, 04:03 PM |
| Sullivan Eric | Principal Accounting Officer | Sep 13, 2016 | Sale | $59.00 | 416 | 24,544 | 5,641 | Sep 15, 2016, 04:03 PM |
| Sullivan Eric | Principal Accounting Officer | Aug 03, 2016 | Option Exercise | $22.20 | 416 | 9,237 | 6,057 | Aug 05, 2016, 04:06 PM |
| Sullivan Eric | Principal Accounting Officer | Aug 03, 2016 | Sale | $59.00 | 416 | 24,544 | 5,641 | Aug 05, 2016, 04:06 PM |
| Sullivan Eric | Principal Accounting Officer | Jul 27, 2016 | Option Exercise | $22.20 | 2,912 | 64,659 | 5,618 | Jul 29, 2016, 04:11 PM |
| Sullivan Eric | Principal Accounting Officer | Jul 27, 2016 | Sale | $55.01 | 2,912 | 160,178 | 2,706 | Jul 29, 2016, 04:11 PM |
| Sullivan Eric | Principal Accounting Officer | Jul 20, 2016 | Sale | $44.88 | 1,950 | 87,510 | 2,807 | Jul 21, 2016, 04:08 PM |
| Sullivan Eric | Principal Accounting Officer | Jul 19, 2016 | Sale | $45.40 | 857 | 38,908 | 4,656 | Jul 21, 2016, 04:08 PM |
| Davidson David | Chief Medical Officer | Jul 15, 2016 | Option Exercise | $2.09 | 1,000 | 2,090 | 10,600 | Jul 19, 2016, 04:13 PM |
| Davidson David | Chief Medical Officer | Jul 15, 2016 | Sale | $45.08 | 1,000 | 45,078 | 9,600 | Jul 19, 2016, 04:13 PM |
| Leschly Nick | President and CEO | Jun 24, 2016 | Option Exercise | $3.85 | 19,826 | 76,239 | 355,870 | Jun 28, 2016, 04:11 PM |
| Davidson David | Chief Medical Officer | Jun 15, 2016 | Option Exercise | $2.09 | 1,000 | 2,090 | 10,600 | Jun 16, 2016, 04:17 PM |
| Davidson David | Chief Medical Officer | Jun 15, 2016 | Sale | $40.11 | 1,000 | 40,112 | 9,600 | Jun 16, 2016, 04:17 PM |
| Gregory Philip D | Chief Scientific Officer | Jun 16, 2016 | Sale | $39.52 | 2,931 | 115,833 | 30,069 | Jun 16, 2016, 04:16 PM |
| Davidson David | Chief Medical Officer | May 16, 2016 | Option Exercise | $2.09 | 1,000 | 2,090 | 10,600 | May 18, 2016, 04:14 PM |
| Davidson David | Chief Medical Officer | May 16, 2016 | Sale | $38.73 | 1,000 | 38,729 | 9,600 | May 18, 2016, 04:14 PM |
| Davidson David | Chief Medical Officer | Apr 15, 2016 | Option Exercise | $2.09 | 1,000 | 2,090 | 10,600 | Apr 19, 2016, 04:07 PM |
| Davidson David | Chief Medical Officer | Apr 15, 2016 | Sale | $49.63 | 1,000 | 49,630 | 9,600 | Apr 19, 2016, 04:07 PM |
| Davidson David | Chief Medical Officer | Mar 15, 2016 | Option Exercise | $2.09 | 1,000 | 2,090 | 10,600 | Mar 17, 2016, 04:13 PM |
| Davidson David | Chief Medical Officer | Mar 15, 2016 | Sale | $46.13 | 1,000 | 46,125 | 9,800 | Mar 17, 2016, 04:13 PM |
| Davidson David | Chief Medical Officer | Feb 16, 2016 | Option Exercise | $2.09 | 1,000 | 2,090 | 1,000 | Feb 18, 2016, 04:34 PM |
| Davidson David | Chief Medical Officer | Feb 16, 2016 | Sale | $45.18 | 1,000 | 45,176 | 0 | Feb 18, 2016, 04:34 PM |
| Davidson David | Chief Medical Officer | Jan 15, 2016 | Option Exercise | $2.09 | 1,000 | 2,090 | 1,000 | Jan 20, 2016, 04:08 PM |
| Davidson David | Chief Medical Officer | Jan 15, 2016 | Sale | $44.39 | 1,000 | 44,392 | 0 | Jan 20, 2016, 04:08 PM |
| Cole Jason | SVP, Secy. & General Counsel | Dec 21, 2015 | Option Exercise | $22.53 | 4,438 | 99,988 | 4,438 | Dec 22, 2015, 04:08 PM |
| Davidson David | Chief Medical Officer | Dec 15, 2015 | Option Exercise | $2.09 | 1,000 | 2,090 | 1,000 | Dec 17, 2015, 04:14 PM |
| Davidson David | Chief Medical Officer | Dec 15, 2015 | Sale | $58.55 | 1,000 | 58,546 | 0 | Dec 17, 2015, 04:14 PM |
| Leschly Nick | President and CEO | Dec 07, 2015 | Option Exercise | $2.36 | 66,720 | 157,418 | 313,241 | Dec 09, 2015, 04:02 PM |
| Leschly Nick | President and CEO | Dec 08, 2015 | Buy | $51.75 | 9,682 | 501,007 | 17,186 | Dec 09, 2015, 04:02 PM |
| Sullivan Eric | Principal Accounting Officer | Dec 02, 2015 | Option Exercise | $22.20 | 416 | 9,237 | 3,634 | Dec 04, 2015, 08:59 AM |
| Sullivan Eric | Principal Accounting Officer | Dec 02, 2015 | Sale | $81.13 | 416 | 33,751 | 3,218 | Dec 04, 2015, 08:59 AM |
| Davidson David | Chief Medical Officer | Nov 16, 2015 | Option Exercise | $2.09 | 2,000 | 4,180 | 2,000 | Nov 18, 2015, 04:09 PM |
| Davidson David | Chief Medical Officer | Nov 16, 2015 | Sale | $70.99 | 2,000 | 141,988 | 730 | Nov 18, 2015, 04:09 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Nov 10, 2015 | Option Exercise | $2.09 | 11,000 | 22,990 | 11,000 | Nov 12, 2015, 04:03 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Nov 10, 2015 | Sale | $74.60 | 11,000 | 820,649 | 0 | Nov 12, 2015, 04:03 PM |
| Sullivan Eric | Principal Accounting Officer | Nov 02, 2015 | Option Exercise | $22.20 | 416 | 9,237 | 3,634 | Nov 04, 2015, 08:48 AM |
| Sullivan Eric | Principal Accounting Officer | Nov 02, 2015 | Sale | $77.87 | 416 | 32,394 | 3,218 | Nov 04, 2015, 08:48 AM |
| Davidson David | Chief Medical Officer | Oct 15, 2015 | Option Exercise | $2.09 | 2,000 | 4,180 | 2,000 | Oct 19, 2015, 04:30 PM |
| Davidson David | Chief Medical Officer | Oct 15, 2015 | Sale | $79.70 | 2,000 | 159,399 | 1,425 | Oct 19, 2015, 04:30 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Oct 12, 2015 | Option Exercise | $2.09 | 11,000 | 22,990 | 11,000 | Oct 14, 2015, 04:03 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Oct 12, 2015 | Sale | $88.06 | 11,000 | 968,634 | 5,929 | Oct 14, 2015, 04:03 PM |
| Cole Jason | SVP, Secy. & General Counsel | Oct 09, 2015 | Option Exercise | $22.53 | 5,000 | 112,650 | 5,000 | Oct 13, 2015, 04:04 PM |
| Cole Jason | SVP, Secy. & General Counsel | Oct 09, 2015 | Sale | $86.91 | 5,000 | 434,541 | 3,000 | Oct 13, 2015, 04:04 PM |
| LYNCH DANIEL | Director | Oct 05, 2015 | Option Exercise | $2.09 | 3,000 | 6,259 | 3,000 | Oct 07, 2015, 04:06 PM |
| LYNCH DANIEL | Director | Oct 05, 2015 | Sale | $100.41 | 3,000 | 301,242 | 600 | Oct 07, 2015, 04:06 PM |
| Sullivan Eric | Principal Accounting Officer | Oct 02, 2015 | Option Exercise | $22.20 | 416 | 9,237 | 3,634 | Oct 06, 2015, 04:06 PM |
| Sullivan Eric | Principal Accounting Officer | Oct 02, 2015 | Sale | $86.10 | 416 | 35,820 | 3,318 | Oct 06, 2015, 04:06 PM |
| LYNCH DANIEL | Director | Sep 17, 2015 | Option Exercise | $2.09 | 1,500 | 3,130 | 1,500 | Sep 21, 2015, 04:13 PM |
| LYNCH DANIEL | Director | Sep 17, 2015 | Sale | $140.06 | 1,500 | 210,089 | 0 | Sep 21, 2015, 04:13 PM |
| Davidson David | Chief Medical Officer | Sep 15, 2015 | Option Exercise | $2.09 | 2,000 | 4,180 | 2,000 | Sep 17, 2015, 04:04 PM |
| Davidson David | Chief Medical Officer | Sep 15, 2015 | Sale | $129.98 | 2,000 | 259,962 | 721 | Sep 17, 2015, 04:04 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Sep 10, 2015 | Option Exercise | $5.50 | 11,000 | 60,504 | 11,000 | Sep 14, 2015, 04:08 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Sep 10, 2015 | Sale | $130.02 | 11,000 | 1,430,246 | 10,176 | Sep 14, 2015, 04:08 PM |
| Cole Jason | SVP, Secy. & General Counsel | Sep 09, 2015 | Option Exercise | $22.53 | 2,000 | 45,060 | 2,000 | Sep 11, 2015, 04:05 PM |
| Cole Jason | SVP, Secy. & General Counsel | Sep 09, 2015 | Sale | $136.56 | 2,000 | 273,120 | 1,300 | Sep 11, 2015, 04:05 PM |
| Leschly Nick | President and CEO | Sep 08, 2015 | Option Exercise | $5.50 | 125,000 | 687,550 | 371,521 | Sep 10, 2015, 04:06 PM |
| Leschly Nick | President and CEO | Sep 08, 2015 | Sale | $135.24 | 125,000 | 16,904,671 | 369,421 | Sep 10, 2015, 04:06 PM |
| LYNCH DANIEL | Director | Sep 08, 2015 | Option Exercise | $2.09 | 7,000 | 14,605 | 7,000 | Sep 10, 2015, 04:05 PM |
| LYNCH DANIEL | Director | Sep 08, 2015 | Sale | $132.75 | 7,000 | 929,254 | 6,500 | Sep 10, 2015, 04:05 PM |
| Sullivan Eric | Principal Accounting Officer | Sep 02, 2015 | Option Exercise | $22.20 | 416 | 9,237 | 3,634 | Sep 04, 2015, 08:33 AM |
| Sullivan Eric | Principal Accounting Officer | Sep 02, 2015 | Sale | $130.94 | 416 | 54,471 | 3,218 | Sep 04, 2015, 08:33 AM |
| Mandell James | Director | Sep 01, 2015 | Option Exercise | $21.43 | 1,500 | 32,145 | 1,500 | Sep 03, 2015, 04:01 PM |
| Mandell James | Director | Sep 01, 2015 | Sale | $125.96 | 1,500 | 188,938 | 858 | Sep 03, 2015, 04:01 PM |
| Davidson David | Chief Medical Officer | Aug 17, 2015 | Option Exercise | $2.09 | 2,000 | 4,180 | 2,000 | Aug 19, 2015, 04:14 PM |
| Davidson David | Chief Medical Officer | Aug 17, 2015 | Sale | $125.33 | 2,000 | 250,656 | 739 | Aug 19, 2015, 04:14 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Aug 10, 2015 | Option Exercise | $2.09 | 11,000 | 22,990 | 11,000 | Aug 12, 2015, 04:03 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Aug 10, 2015 | Sale | $148.44 | 11,000 | 1,632,855 | 6,437 | Aug 12, 2015, 04:03 PM |
| Cole Jason | SVP, Secy. & General Counsel | Aug 10, 2015 | Option Exercise | $22.53 | 30,000 | 675,900 | 2,000 | Aug 12, 2015, 04:03 PM |
| Cole Jason | SVP, Secy. & General Counsel | Aug 10, 2015 | Sale | $148.44 | 30,000 | 4,453,248 | 1,167 | Aug 12, 2015, 04:03 PM |
| Mandell James | Director | Aug 10, 2015 | Option Exercise | $21.43 | 1,500 | 32,145 | 1,500 | Aug 12, 2015, 04:02 PM |
| Mandell James | Director | Aug 10, 2015 | Sale | $148.44 | 1,500 | 222,662 | 874 | Aug 12, 2015, 04:02 PM |
| LYNCH DANIEL | Director | Aug 07, 2015 | Option Exercise | $2.09 | 29,500 | 61,549 | 29,500 | Aug 11, 2015, 03:29 PM |
| LYNCH DANIEL | Director | Aug 07, 2015 | Sale | $140.33 | 29,500 | 4,139,690 | 29,421 | Aug 11, 2015, 03:29 PM |
| Leschly Nick | President and CEO | Aug 07, 2015 | Option Exercise | $4.56 | 2,500,000 | 11,390,765 | 371,521 | Aug 11, 2015, 02:56 PM |
| Leschly Nick | President and CEO | Aug 07, 2015 | Sale | $139.32 | 2,500,000 | 348,311,581 | 371,102 | Aug 11, 2015, 02:56 PM |
| Sullivan Eric | Principal Accounting Officer | Aug 03, 2015 | Option Exercise | $22.20 | 416 | 9,237 | 3,634 | Aug 05, 2015, 04:02 PM |
| Sullivan Eric | Principal Accounting Officer | Aug 03, 2015 | Sale | $165.39 | 416 | 68,801 | 3,583 | Aug 05, 2015, 04:02 PM |
| Sullivan Eric | Principal Accounting Officer | Jul 20, 2015 | Sale | $162.56 | 682 | 110,869 | 3,260 | Jul 21, 2015, 04:02 PM |
| Sullivan Eric | Principal Accounting Officer | Jul 17, 2015 | Sale | $164.58 | 444 | 73,074 | 3,772 | Jul 21, 2015, 04:02 PM |
| Davidson David | Chief Medical Officer | Jul 15, 2015 | Option Exercise | $2.09 | 2,000 | 4,180 | 2,000 | Jul 17, 2015, 07:43 AM |
| Davidson David | Chief Medical Officer | Jul 15, 2015 | Sale | $165.96 | 2,000 | 331,927 | 575 | Jul 17, 2015, 07:43 AM |
| Walsh Jeffrey T. | Chief Operating Officer | Jul 10, 2015 | Option Exercise | $2.09 | 11,000 | 22,990 | 11,000 | Jul 13, 2015, 04:13 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jul 10, 2015 | Sale | $158.63 | 11,000 | 1,744,943 | 7,230 | Jul 13, 2015, 04:13 PM |
| Cole Jason | SVP, Secy. & General Counsel | Jul 09, 2015 | Option Exercise | $22.53 | 5,000 | 112,650 | 5,000 | Jul 13, 2015, 04:12 PM |
| Cole Jason | SVP, Secy. & General Counsel | Jul 09, 2015 | Sale | $158.19 | 5,000 | 790,961 | 4,600 | Jul 13, 2015, 04:12 PM |
| Sullivan Eric | Principal Accounting Officer | Jul 02, 2015 | Option Exercise | $22.20 | 416 | 9,237 | 4,632 | Jul 06, 2015, 04:11 PM |
| Sullivan Eric | Principal Accounting Officer | Jul 02, 2015 | Sale | $163.47 | 416 | 68,003 | 4,216 | Jul 06, 2015, 04:11 PM |
| Davidson David | Chief Medical Officer | Jun 15, 2015 | Option Exercise | $2.09 | 2,000 | 4,180 | 2,000 | Jun 17, 2015, 04:08 PM |
| Davidson David | Chief Medical Officer | Jun 15, 2015 | Sale | $183.34 | 2,000 | 366,673 | 1,356 | Jun 17, 2015, 04:08 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jun 10, 2015 | Option Exercise | $2.09 | 11,000 | 22,990 | 11,000 | Jun 11, 2015, 04:03 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jun 10, 2015 | Sale | $179.70 | 11,000 | 1,976,722 | 8,800 | Jun 11, 2015, 04:03 PM |
| Cole Jason | SVP, Secy. & General Counsel | Jun 09, 2015 | Option Exercise | $22.53 | 2,000 | 45,060 | 2,000 | Jun 11, 2015, 04:02 PM |
| Cole Jason | SVP, Secy. & General Counsel | Jun 09, 2015 | Sale | $186.09 | 2,000 | 372,177 | 1,868 | Jun 11, 2015, 04:02 PM |
| Sullivan Eric | Principal Accounting Officer | Jun 02, 2015 | Option Exercise | $22.20 | 416 | 9,237 | 732 | Jun 04, 2015, 04:01 PM |
| Sullivan Eric | Principal Accounting Officer | Jun 02, 2015 | Sale | $190.20 | 416 | 79,122 | 316 | Jun 04, 2015, 04:01 PM |
| Finer Mitchell H. | Chief Scientific Officer | Jun 01, 2015 | Option Exercise | $24.47 | 15,000 | 367,050 | 15,000 | Jun 03, 2015, 11:53 AM |
| Finer Mitchell H. | Chief Scientific Officer | Jun 01, 2015 | Sale | $190.25 | 15,000 | 2,853,802 | 10,158 | Jun 03, 2015, 11:53 AM |
| Finer Mitchell H. | Chief Scientific Officer | May 22, 2015 | Option Exercise | $5.50 | 15,000 | 82,506 | 15,000 | May 27, 2015, 04:11 PM |
| Finer Mitchell H. | Chief Scientific Officer | May 22, 2015 | Sale | $170.32 | 15,000 | 2,554,799 | 13,400 | May 27, 2015, 04:11 PM |
| Finer Mitchell H. | Chief Scientific Officer | May 15, 2015 | Option Exercise | $5.50 | 15,000 | 82,506 | 15,000 | May 19, 2015, 04:07 PM |
| Finer Mitchell H. | Chief Scientific Officer | May 15, 2015 | Sale | $154.33 | 15,000 | 2,315,019 | 10,151 | May 19, 2015, 04:07 PM |
| Davidson David | Chief Medical Officer | May 15, 2015 | Option Exercise | $2.09 | 2,000 | 4,180 | 2,000 | May 19, 2015, 04:07 PM |
| Davidson David | Chief Medical Officer | May 15, 2015 | Sale | $154.33 | 2,000 | 308,669 | 1,352 | May 19, 2015, 04:07 PM |
| Walsh Jeffrey T. | Chief Operating Officer | May 11, 2015 | Option Exercise | $2.09 | 11,000 | 22,990 | 11,000 | May 13, 2015, 04:05 PM |
| Walsh Jeffrey T. | Chief Operating Officer | May 11, 2015 | Sale | $163.92 | 11,000 | 1,803,132 | 9,880 | May 13, 2015, 04:05 PM |
| Cole Jason | SVP, Secy. & General Counsel | May 11, 2015 | Option Exercise | $22.53 | 9,000 | 202,770 | 9,000 | May 13, 2015, 04:05 PM |
| Cole Jason | SVP, Secy. & General Counsel | May 11, 2015 | Sale | $163.92 | 9,000 | 1,475,292 | 8,080 | May 13, 2015, 04:05 PM |
| Sullivan Eric | Principal Accounting Officer | May 04, 2015 | Option Exercise | $22.20 | 416 | 9,237 | 732 | May 06, 2015, 08:38 AM |
| Sullivan Eric | Principal Accounting Officer | May 04, 2015 | Sale | $131.84 | 416 | 54,844 | 543 | May 06, 2015, 08:38 AM |
| Finer Mitchell H. | Chief Scientific Officer | May 04, 2015 | Option Exercise | $5.31 | 15,000 | 79,724 | 15,000 | May 06, 2015, 08:38 AM |
| Finer Mitchell H. | Chief Scientific Officer | May 04, 2015 | Sale | $131.84 | 15,000 | 1,977,549 | 8,114 | May 06, 2015, 08:38 AM |
| Finer Mitchell H. | Chief Scientific Officer | Apr 20, 2015 | Option Exercise | $5.24 | 15,000 | 78,525 | 15,000 | Apr 22, 2015, 04:01 PM |
| Finer Mitchell H. | Chief Scientific Officer | Apr 20, 2015 | Sale | $126.03 | 15,000 | 1,890,408 | 12,480 | Apr 22, 2015, 04:01 PM |
| Davidson David | Chief Medical Officer | Apr 15, 2015 | Option Exercise | $2.09 | 2,000 | 4,180 | 2,000 | Apr 17, 2015, 04:04 PM |
| Davidson David | Chief Medical Officer | Apr 15, 2015 | Sale | $130.18 | 2,000 | 260,355 | 105 | Apr 17, 2015, 04:04 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Apr 10, 2015 | Option Exercise | $2.09 | 21,000 | 43,890 | 21,000 | Apr 14, 2015, 04:14 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Apr 10, 2015 | Sale | $126.21 | 21,000 | 2,650,458 | 19,240 | Apr 14, 2015, 04:14 PM |
| Finer Mitchell H. | Chief Scientific Officer | Apr 06, 2015 | Option Exercise | $3.56 | 15,000 | 53,412 | 15,000 | Apr 08, 2015, 04:13 PM |
| Finer Mitchell H. | Chief Scientific Officer | Apr 06, 2015 | Sale | $118.72 | 15,000 | 1,780,853 | 14,321 | Apr 08, 2015, 04:13 PM |
| Sullivan Eric | Principal Accounting Officer | Apr 02, 2015 | Option Exercise | $23.53 | 2,998 | 70,534 | 3,314 | Apr 03, 2015, 11:53 AM |
| Sullivan Eric | Principal Accounting Officer | Apr 02, 2015 | Sale | $117.81 | 2,998 | 353,194 | 1,321 | Apr 03, 2015, 11:53 AM |
| Finer Mitchell H. | Chief Scientific Officer | Apr 01, 2015 | Option Exercise | $2.09 | 30,000 | 62,592 | 30,000 | Apr 03, 2015, 11:45 AM |
| Finer Mitchell H. | Chief Scientific Officer | Apr 01, 2015 | Sale | $117.95 | 30,000 | 3,538,385 | 19,059 | Apr 03, 2015, 11:45 AM |
| Walsh Jeffrey T. | Chief Operating Officer | Mar 10, 2015 | Option Exercise | $2.09 | 10,500 | 21,945 | 10,500 | Mar 11, 2015, 04:16 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Mar 10, 2015 | Sale | $110.06 | 10,500 | 1,155,617 | 4,284 | Mar 11, 2015, 04:16 PM |
| Cole Jason | SVP, Secy. & General Counsel | Mar 09, 2015 | Option Exercise | $22.53 | 10,000 | 225,300 | 10,000 | Mar 11, 2015, 04:16 PM |
| Cole Jason | SVP, Secy. & General Counsel | Mar 09, 2015 | Sale | $111.52 | 10,000 | 1,115,168 | 5,520 | Mar 11, 2015, 04:16 PM |
| Davidson David | Chief Medical Officer | Mar 02, 2015 | Option Exercise | $2.09 | 4,000 | 8,360 | 4,000 | Mar 03, 2015, 04:13 PM |
| Davidson David | Chief Medical Officer | Mar 02, 2015 | Sale | $94.84 | 4,000 | 379,378 | 1,400 | Mar 03, 2015, 04:13 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Feb 10, 2015 | Option Exercise | $2.09 | 10,500 | 21,945 | 10,500 | Feb 12, 2015, 04:14 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Feb 10, 2015 | Sale | $85.34 | 10,500 | 896,095 | 2,976 | Feb 12, 2015, 04:14 PM |
| Davidson David | Chief Medical Officer | Feb 02, 2015 | Option Exercise | $2.09 | 4,000 | 8,346 | 4,000 | Feb 04, 2015, 04:06 PM |
| Davidson David | Chief Medical Officer | Feb 02, 2015 | Sale | $95.63 | 4,000 | 382,501 | 2,142 | Feb 04, 2015, 04:06 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jan 12, 2015 | Option Exercise | $2.09 | 10,500 | 21,945 | 10,500 | Jan 14, 2015, 08:08 AM |
| Walsh Jeffrey T. | Chief Operating Officer | Jan 12, 2015 | Sale | $103.57 | 10,500 | 1,087,453 | 9,304 | Jan 14, 2015, 08:08 AM |
| Sullivan Eric | Principal Accounting Officer | Jan 02, 2015 | Option Exercise | $20.95 | 3,750 | 78,568 | 3,750 | Jan 06, 2015, 04:05 PM |
| Sullivan Eric | Principal Accounting Officer | Jan 02, 2015 | Sale | $90.01 | 3,750 | 337,531 | 2,581 | Jan 06, 2015, 04:05 PM |
| Finer Mitchell H. | Chief Scientific Officer | Jan 02, 2015 | Option Exercise | $1.34 | 30,000 | 40,127 | 30,000 | Jan 06, 2015, 04:04 PM |
| Finer Mitchell H. | Chief Scientific Officer | Jan 02, 2015 | Sale | $90.01 | 30,000 | 2,700,248 | 20,645 | Jan 06, 2015, 04:04 PM |
| Davidson David | Chief Medical Officer | Jan 02, 2015 | Option Exercise | $2.09 | 4,000 | 8,346 | 4,000 | Jan 06, 2015, 04:04 PM |
| Davidson David | Chief Medical Officer | Jan 02, 2015 | Sale | $90.01 | 4,000 | 360,033 | 2,761 | Jan 06, 2015, 04:04 PM |
| Schenkein David P | Director | Dec 19, 2014 | Buy | $85.00 | 1,176 | 99,960 | 1,176 | Dec 22, 2014, 08:04 AM |
| MARAGANORE JOHN | Director | Dec 19, 2014 | Buy | $85.00 | 2,352 | 199,920 | 5,293 | Dec 22, 2014, 08:03 AM |
| Walsh Jeffrey T. | Chief Operating Officer | Dec 10, 2014 | Option Exercise | $2.09 | 10,500 | 21,945 | 10,500 | Dec 11, 2014, 04:13 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Dec 09, 2014 | Option Exercise | $2.09 | 33,000 | 68,970 | 33,000 | Dec 11, 2014, 04:13 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Dec 10, 2014 | Sale | $82.03 | 10,500 | 861,364 | 3,961 | Dec 11, 2014, 04:13 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Dec 09, 2014 | Sale | $76.80 | 33,000 | 2,534,281 | 20,517 | Dec 11, 2014, 04:13 PM |
| Davidson David | Chief Medical Officer | Dec 08, 2014 | Option Exercise | $2.09 | 13,788 | 28,767 | 13,788 | Dec 09, 2014, 04:12 PM |
| Davidson David | Chief Medical Officer | Dec 05, 2014 | Option Exercise | $2.09 | 1,212 | 2,529 | 1,212 | Dec 09, 2014, 04:12 PM |
| Davidson David | Chief Medical Officer | Dec 05, 2014 | Sale | $45.00 | 1,212 | 54,544 | 0 | Dec 09, 2014, 04:12 PM |
| Davidson David | Chief Medical Officer | Dec 08, 2014 | Sale | $46.20 | 13,788 | 637,008 | 4,937 | Dec 09, 2014, 04:12 PM |
| Davidson David | Chief Medical Officer | Dec 03, 2014 | Option Exercise | $2.09 | 3,000 | 6,259 | 3,000 | Dec 05, 2014, 08:24 AM |
| Davidson David | Chief Medical Officer | Dec 03, 2014 | Sale | $41.65 | 3,000 | 124,957 | 164 | Dec 05, 2014, 08:24 AM |
| Finer Mitchell H. | Chief Scientific Officer | Dec 01, 2014 | Option Exercise | $0.95 | 18,000 | 17,100 | 18,000 | Dec 03, 2014, 09:45 AM |
| Finer Mitchell H. | Chief Scientific Officer | Dec 01, 2014 | Sale | $39.70 | 18,000 | 714,625 | 5,602 | Dec 03, 2014, 09:45 AM |
| Leschly Nick | President and CEO | Dec 01, 2014 | Sale | $39.70 | 2,417 | 95,958 | 246,408 | Dec 03, 2014, 09:26 AM |
| Leschly Nick | President and CEO | Dec 01, 2014 | Sale | $39.70 | 2,417 | 95,958 | 246,408 | Dec 03, 2014, 09:25 AM |
| Walsh Jeffrey T. | Chief Operating Officer | Nov 10, 2014 | Option Exercise | $2.09 | 7,500 | 15,675 | 7,500 | Nov 12, 2014, 04:19 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Nov 10, 2014 | Sale | $41.27 | 7,500 | 309,527 | 900 | Nov 12, 2014, 04:19 PM |
| Davidson David | Chief Medical Officer | Nov 03, 2014 | Option Exercise | $2.09 | 3,000 | 6,259 | 3,000 | Nov 05, 2014, 08:21 AM |
| Davidson David | Chief Medical Officer | Nov 03, 2014 | Sale | $41.68 | 3,000 | 125,029 | 0 | Nov 05, 2014, 08:21 AM |
| Leschly Nick | President and CEO | Nov 03, 2014 | Sale | $41.68 | 25,000 | 1,041,912 | 248,070 | Nov 05, 2014, 08:20 AM |
| Leschly Nick | President and CEO | Sep 02, 2014 | Sale | $38.00 | 8,100 | 307,800 | 314,901 | Oct 29, 2014, 04:16 PM |
| Leschly Nick | President and CEO | Oct 24, 2014 | Sale | $40.22 | 33,900 | 1,363,458 | 273,170 | Oct 28, 2014, 08:28 AM |
| GILLIS STEVEN | Director | Oct 09, 2014 | Sale | $35.25 | 115,000 | 4,053,888 | 1,041,111 | Oct 14, 2014, 05:07 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Oct 10, 2014 | Option Exercise | $2.09 | 7,500 | 15,675 | 7,500 | Oct 14, 2014, 04:07 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Oct 10, 2014 | Sale | $33.16 | 7,500 | 248,700 | 0 | Oct 14, 2014, 04:07 PM |
| Finer Mitchell H. | Chief Scientific Officer | Oct 08, 2014 | Option Exercise | $2.09 | 34,518 | 72,143 | 15,926 | Oct 10, 2014, 07:59 AM |
| Finer Mitchell H. | Chief Scientific Officer | Oct 08, 2014 | Sale | $33.52 | 34,518 | 1,156,937 | 0 | Oct 10, 2014, 07:59 AM |
| GILLIS STEVEN | Director | Oct 07, 2014 | Sale | $35.15 | 6,700 | 235,505 | 1,156,111 | Oct 07, 2014, 05:34 PM |
| GILLIS STEVEN | Director | Oct 06, 2014 | Sale | $35.16 | 24,100 | 847,356 | 1,162,811 | Oct 07, 2014, 05:34 PM |
| GILLIS STEVEN | Director | Oct 03, 2014 | Sale | $35.74 | 26,635 | 951,935 | 1,186,911 | Oct 07, 2014, 05:34 PM |
| Leschly Nick | President and CEO | Oct 01, 2014 | Sale | $34.55 | 8,000 | 276,400 | 307,070 | Oct 03, 2014, 08:15 AM |
| Davidson David | Chief Medical Officer | Oct 01, 2014 | Option Exercise | $2.09 | 3,000 | 6,270 | 3,000 | Oct 03, 2014, 08:14 AM |
| Davidson David | Chief Medical Officer | Oct 01, 2014 | Sale | $34.55 | 3,000 | 103,650 | 0 | Oct 03, 2014, 08:14 AM |
| GILLIS STEVEN | Director | Oct 02, 2014 | Sale | $34.87 | 47,554 | 1,658,208 | 1,213,546 | Oct 02, 2014, 05:43 PM |
| GILLIS STEVEN | Director | Oct 01, 2014 | Sale | $34.75 | 11,516 | 400,181 | 1,261,100 | Oct 02, 2014, 05:43 PM |
| GILLIS STEVEN | Director | Sep 30, 2014 | Sale | $36.08 | 32,095 | 1,157,988 | 1,272,616 | Oct 02, 2014, 05:43 PM |
| TEPPER ROBERT I | Director | Sep 11, 2014 | Sale | $36.52 | 87,000 | 3,177,240 | 2,329,974 | Sep 12, 2014, 04:11 PM |
| TEPPER ROBERT I | Director | Sep 12, 2014 | Sale | $36.59 | 38,000 | 1,390,420 | 1,215,054 | Sep 12, 2014, 04:11 PM |
| THIRD ROCK VENTURES LP | 10% Owner | Sep 12, 2014 | Sale | $36.59 | 38,000 | 1,390,420 | 1,215,054 | Sep 12, 2014, 04:07 PM |
| THIRD ROCK VENTURES LP | 10% Owner | Sep 11, 2014 | Sale | $36.52 | 87,000 | 3,177,240 | 2,329,974 | Sep 12, 2014, 04:07 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Sep 10, 2014 | Option Exercise | $2.09 | 7,500 | 15,675 | 7,500 | Sep 12, 2014, 08:39 AM |
| Walsh Jeffrey T. | Chief Operating Officer | Sep 10, 2014 | Sale | $37.02 | 7,500 | 277,650 | 0 | Sep 12, 2014, 08:39 AM |
| Leschly Nick | President and CEO | Aug 29, 2014 | Sale | $40.01 | 2,300 | 92,023 | 323,001 | Sep 03, 2014, 04:04 PM |
| Leschly Nick | President and CEO | Sep 02, 2014 | Sale | $38.00 | 8,000 | 304,000 | 315,001 | Sep 03, 2014, 04:04 PM |
| Finer Mitchell H. | Chief Scientific Officer | Sep 02, 2014 | Option Exercise | $0.95 | 18,000 | 17,100 | 18,000 | Sep 03, 2014, 04:03 PM |
| Finer Mitchell H. | Chief Scientific Officer | Sep 02, 2014 | Sale | $38.00 | 18,000 | 684,000 | 0 | Sep 03, 2014, 04:03 PM |
| Davidson David | Chief Medical Officer | Sep 02, 2014 | Option Exercise | $2.09 | 3,000 | 6,270 | 3,000 | Sep 03, 2014, 04:02 PM |
| Davidson David | Chief Medical Officer | Sep 02, 2014 | Sale | $38.00 | 3,000 | 114,000 | 0 | Sep 03, 2014, 04:02 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Aug 11, 2014 | Option Exercise | $2.09 | 7,500 | 15,675 | 7,500 | Aug 13, 2014, 08:23 AM |
| Walsh Jeffrey T. | Chief Operating Officer | Aug 11, 2014 | Sale | $34.26 | 7,500 | 256,950 | 0 | Aug 13, 2014, 08:23 AM |
| Leschly Nick | President and CEO | Aug 01, 2014 | Sale | $33.62 | 8,000 | 268,960 | 325,301 | Aug 05, 2014, 08:05 AM |
| Davidson David | Chief Medical Officer | Aug 01, 2014 | Option Exercise | $2.09 | 3,000 | 6,270 | 3,000 | Aug 05, 2014, 08:03 AM |
| Davidson David | Chief Medical Officer | Aug 01, 2014 | Sale | $33.62 | 3,000 | 100,860 | 0 | Aug 05, 2014, 08:03 AM |
| MARAGANORE JOHN | Director | Jul 14, 2014 | Buy | $34.00 | 2,941 | 99,994 | 2,941 | Jul 14, 2014, 04:08 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jul 10, 2014 | Option Exercise | $2.09 | 7,500 | 15,675 | 7,500 | Jul 14, 2014, 04:04 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jul 10, 2014 | Sale | $33.20 | 7,500 | 249,000 | 0 | Jul 14, 2014, 04:04 PM |
| Leschly Nick | President and CEO | Jul 03, 2014 | Sale | $40.00 | 1,300 | 52,000 | 333,301 | Jul 03, 2014, 06:39 PM |
| Leschly Nick | President and CEO | Jul 02, 2014 | Sale | $40.02 | 943 | 37,739 | 334,601 | Jul 03, 2014, 06:39 PM |
| Leschly Nick | President and CEO | Jul 01, 2014 | Sale | $39.84 | 20,040 | 798,394 | 335,544 | Jul 03, 2014, 06:39 PM |
| Davidson David | Chief Medical Officer | Jul 01, 2014 | Option Exercise | $2.09 | 3,000 | 6,270 | 3,000 | Jul 03, 2014, 06:24 AM |
| Davidson David | Chief Medical Officer | Jul 01, 2014 | Sale | $39.55 | 3,000 | 118,650 | 0 | Jul 03, 2014, 06:24 AM |
| Leschly Nick | President and CEO | Jun 20, 2014 | Sale | $40.06 | 17,075 | 684,025 | 355,584 | Jun 24, 2014, 04:37 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jun 16, 2014 | Option Exercise | $2.09 | 1,500 | 3,135 | 1,500 | Jun 18, 2014, 04:25 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jun 16, 2014 | Sale | $39.86 | 1,500 | 59,790 | 0 | Jun 18, 2014, 04:25 PM |
| Finer Mitchell H. | Chief Scientific Officer | Jun 16, 2014 | Option Exercise | $0.95 | 10,000 | 9,500 | 10,000 | Jun 18, 2014, 04:24 PM |
| Finer Mitchell H. | Chief Scientific Officer | Jun 16, 2014 | Sale | $39.84 | 10,000 | 398,400 | 0 | Jun 18, 2014, 04:24 PM |
| Leschly Nick | President and CEO | Jun 16, 2014 | Sale | $40.02 | 42,925 | 1,717,776 | 406,584 | Jun 18, 2014, 04:23 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jun 10, 2014 | Option Exercise | $2.09 | 6,000 | 12,540 | 6,000 | Jun 12, 2014, 04:14 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jun 10, 2014 | Sale | $24.23 | 6,000 | 145,380 | 0 | Jun 12, 2014, 04:14 PM |
| Leschly Nick | President and CEO | Jun 02, 2014 | Sale | $22.21 | 5,000 | 111,050 | 415,584 | Jun 04, 2014, 08:55 AM |
| Finer Mitchell H. | Chief Scientific Officer | Jun 02, 2014 | Option Exercise | $0.95 | 8,000 | 7,600 | 8,000 | Jun 04, 2014, 08:54 AM |
| Finer Mitchell H. | Chief Scientific Officer | Jun 02, 2014 | Sale | $22.21 | 8,000 | 177,680 | 0 | Jun 04, 2014, 08:54 AM |
| Davidson David | Chief Medical Officer | Jun 02, 2014 | Option Exercise | $2.09 | 3,000 | 6,270 | 3,000 | Jun 04, 2014, 08:53 AM |
| Davidson David | Chief Medical Officer | Jun 02, 2014 | Sale | $22.21 | 3,000 | 66,630 | 0 | Jun 04, 2014, 08:53 AM |
| Walsh Jeffrey T. | Chief Operating Officer | May 14, 2014 | Option Exercise | $2.09 | 1,500 | 3,135 | 1,500 | May 16, 2014, 08:09 AM |
| Walsh Jeffrey T. | Chief Operating Officer | May 14, 2014 | Sale | $20.03 | 1,500 | 30,045 | 0 | May 16, 2014, 08:09 AM |
| Walsh Jeffrey T. | Chief Operating Officer | May 12, 2014 | Option Exercise | $2.09 | 4,500 | 9,405 | 4,500 | May 14, 2014, 08:15 AM |
| Walsh Jeffrey T. | Chief Operating Officer | May 12, 2014 | Sale | $18.93 | 4,500 | 85,185 | 0 | May 14, 2014, 08:15 AM |
| Leschly Nick | President and CEO | May 07, 2014 | Option Exercise | $2.09 | 116,266 | 242,996 | 420,584 | May 09, 2014, 08:41 AM |
| Leschly Nick | President and CEO | May 01, 2014 | Sale | $20.07 | 5,000 | 100,350 | 304,318 | May 02, 2014, 04:20 PM |
| Davidson David | Chief Medical Officer | May 01, 2014 | Option Exercise | $2.09 | 4,000 | 8,360 | 4,000 | May 02, 2014, 04:19 PM |
| Davidson David | Chief Medical Officer | May 01, 2014 | Sale | $19.85 | 4,000 | 79,400 | 0 | May 02, 2014, 04:19 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Apr 10, 2014 | Option Exercise | $2.09 | 6,000 | 12,540 | 6,000 | Apr 14, 2014, 04:07 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Apr 10, 2014 | Sale | $21.29 | 6,000 | 127,740 | 0 | Apr 14, 2014, 04:07 PM |
| Davidson David | Chief Medical Officer | Apr 01, 2014 | Option Exercise | $2.09 | 4,000 | 8,360 | 4,000 | Apr 03, 2014, 05:09 PM |
| Davidson David | Chief Medical Officer | Apr 01, 2014 | Sale | $22.74 | 4,000 | 90,960 | 0 | Apr 03, 2014, 05:09 PM |
| Leschly Nick | President and CEO | Apr 01, 2014 | Sale | $22.74 | 5,000 | 113,700 | 309,318 | Apr 03, 2014, 05:08 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Mar 10, 2014 | Option Exercise | $2.09 | 6,000 | 12,540 | 6,000 | Mar 12, 2014, 04:35 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Mar 10, 2014 | Sale | $25.80 | 6,000 | 154,800 | 0 | Mar 12, 2014, 04:35 PM |
| Leschly Nick | President and CEO | Mar 03, 2014 | Sale | $24.79 | 5,000 | 123,950 | 314,318 | Mar 05, 2014, 05:05 PM |
| Finer Mitchell H. | Chief Scientific Officer | Mar 03, 2014 | Option Exercise | $0.95 | 8,000 | 7,600 | 8,000 | Mar 05, 2014, 05:05 PM |
| Finer Mitchell H. | Chief Scientific Officer | Mar 03, 2014 | Sale | $24.79 | 8,000 | 198,320 | 0 | Mar 05, 2014, 05:05 PM |
| Davidson David | Chief Medical Officer | Mar 03, 2014 | Option Exercise | $2.09 | 8,000 | 16,720 | 8,000 | Mar 05, 2014, 05:04 PM |
| Davidson David | Chief Medical Officer | Mar 03, 2014 | Sale | $24.79 | 8,000 | 198,320 | 0 | Mar 05, 2014, 05:04 PM |
| Bain Linda | VP, Fin. & Business Operations | Mar 03, 2014 | Option Exercise | $2.09 | 2,500 | 5,225 | 2,500 | Mar 05, 2014, 05:04 PM |
| Bain Linda | VP, Fin. & Business Operations | Feb 26, 2014 | Option Exercise | $2.09 | 500 | 1,045 | 500 | Mar 05, 2014, 05:04 PM |
| Bain Linda | VP, Fin. & Business Operations | Mar 03, 2014 | Sale | $24.79 | 2,500 | 61,975 | 0 | Mar 05, 2014, 05:04 PM |
| Bain Linda | VP, Fin. & Business Operations | Feb 26, 2014 | Sale | $25.03 | 500 | 12,515 | 0 | Mar 05, 2014, 05:04 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Feb 10, 2014 | Option Exercise | $2.09 | 6,000 | 12,540 | 6,000 | Feb 12, 2014, 07:51 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Feb 10, 2014 | Sale | $21.08 | 6,000 | 126,480 | 0 | Feb 12, 2014, 07:51 PM |
| Bain Linda | VP, Fin. & Business Operations | Feb 11, 2014 | Option Exercise | $2.09 | 1,000 | 2,090 | 1,000 | Feb 12, 2014, 07:50 PM |
| Bain Linda | VP, Fin. & Business Operations | Feb 11, 2014 | Sale | $22.50 | 1,000 | 22,500 | 0 | Feb 12, 2014, 07:50 PM |
| Leschly Nick | President and CEO | Feb 03, 2014 | Sale | $21.30 | 5,000 | 106,500 | 319,318 | Feb 05, 2014, 05:02 PM |
| Davidson David | Chief Medical Officer | Feb 03, 2014 | Option Exercise | $2.09 | 8,000 | 16,720 | 8,000 | Feb 05, 2014, 05:02 PM |
| Davidson David | Chief Medical Officer | Feb 03, 2014 | Sale | $21.30 | 8,000 | 170,400 | 0 | Feb 05, 2014, 05:02 PM |
| Bain Linda | VP, Fin. & Business Operations | Feb 03, 2014 | Option Exercise | $2.09 | 3,500 | 7,315 | 3,500 | Feb 05, 2014, 05:01 PM |
| Bain Linda | VP, Fin. & Business Operations | Feb 03, 2014 | Sale | $21.30 | 3,500 | 74,550 | 0 | Feb 05, 2014, 05:01 PM |
| Bain Linda | VP, Fin. & Business Operations | Jan 22, 2014 | Option Exercise | $2.09 | 2,500 | 5,225 | 2,500 | Jan 24, 2014, 05:04 PM |
| Bain Linda | VP, Fin. & Business Operations | Jan 22, 2014 | Sale | $25.11 | 2,500 | 62,775 | 0 | Jan 24, 2014, 05:04 PM |
| TEPPER ROBERT I | Director | Jan 21, 2014 | Sale | $23.91 | 250,000 | 5,977,500 | 2,416,974 | Jan 23, 2014, 05:07 PM |
| THIRD ROCK VENTURES LP | 10% Owner | Jan 21, 2014 | Sale | $23.91 | 250,000 | 5,977,500 | 2,416,974 | Jan 23, 2014, 05:06 PM |
| Finer Mitchell H. | Chief Scientific Officer | Jan 16, 2014 | Option Exercise | $0.95 | 10,000 | 9,500 | 10,000 | Jan 17, 2014, 05:20 PM |
| Finer Mitchell H. | Chief Scientific Officer | Jan 16, 2014 | Sale | $23.52 | 10,000 | 235,200 | 0 | Jan 17, 2014, 05:20 PM |
| THIRD ROCK VENTURES LP | 10% Owner | Jan 17, 2014 | Sale | $23.96 | 14,000 | 335,440 | 2,666,974 | Jan 17, 2014, 05:12 PM |
| THIRD ROCK VENTURES LP | 10% Owner | Jan 16, 2014 | Sale | $24.02 | 33,000 | 792,660 | 2,680,974 | Jan 17, 2014, 05:12 PM |
| THIRD ROCK VENTURES LP | 10% Owner | Jan 15, 2014 | Sale | $22.14 | 260,000 | 5,756,400 | 2,713,974 | Jan 17, 2014, 05:12 PM |
| TEPPER ROBERT I | Director | Jan 15, 2014 | Sale | $22.14 | 260,000 | 5,756,400 | 2,713,974 | Jan 17, 2014, 05:11 PM |
| TEPPER ROBERT I | Director | Jan 17, 2014 | Sale | $23.96 | 14,000 | 335,440 | 2,666,974 | Jan 17, 2014, 05:11 PM |
| TEPPER ROBERT I | Director | Jan 16, 2014 | Sale | $24.02 | 33,000 | 792,660 | 2,680,974 | Jan 17, 2014, 05:11 PM |
| THIRD ROCK VENTURES LP | 10% Owner | Jan 14, 2014 | Sale | $21.91 | 270,000 | 5,915,700 | 2,973,974 | Jan 14, 2014, 07:27 PM |
| THIRD ROCK VENTURES LP | 10% Owner | Jan 13, 2014 | Sale | $21.80 | 45,000 | 981,000 | 3,243,974 | Jan 14, 2014, 07:27 PM |
| THIRD ROCK VENTURES LP | 10% Owner | Jan 10, 2014 | Sale | $21.98 | 25,000 | 549,500 | 3,288,974 | Jan 14, 2014, 07:27 PM |
| TEPPER ROBERT I | Director | Jan 10, 2014 | Sale | $21.98 | 25,000 | 549,500 | 3,288,974 | Jan 14, 2014, 07:26 PM |
| TEPPER ROBERT I | Director | Jan 14, 2014 | Sale | $21.91 | 270,000 | 5,915,700 | 2,973,974 | Jan 14, 2014, 07:26 PM |
| TEPPER ROBERT I | Director | Jan 13, 2014 | Sale | $21.80 | 45,000 | 981,000 | 3,243,974 | Jan 14, 2014, 07:26 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jan 10, 2014 | Option Exercise | $2.09 | 6,000 | 12,540 | 6,000 | Jan 10, 2014, 07:11 PM |
| Walsh Jeffrey T. | Chief Operating Officer | Jan 10, 2014 | Sale | $21.98 | 6,000 | 131,880 | 0 | Jan 10, 2014, 07:11 PM |
| Leschly Nick | President and CEO | Jan 02, 2014 | Sale | $20.83 | 5,000 | 104,150 | 324,318 | Jan 03, 2014, 05:51 PM |
| Davidson David | Chief Medical Officer | Jan 02, 2014 | Option Exercise | $2.09 | 10,000 | 20,900 | 10,000 | Jan 03, 2014, 05:50 PM |
| Davidson David | Chief Medical Officer | Jan 03, 2014 | Option Exercise | $2.09 | 5,000 | 10,450 | 5,000 | Jan 03, 2014, 05:50 PM |
| Davidson David | Chief Medical Officer | Jan 02, 2014 | Sale | $20.83 | 10,000 | 208,300 | 0 | Jan 03, 2014, 05:50 PM |
| Davidson David | Chief Medical Officer | Jan 03, 2014 | Sale | $20.99 | 5,000 | 104,950 | 0 | Jan 03, 2014, 05:50 PM |
| Bain Linda | VP, Fin. & Business Operations | Jan 02, 2014 | Option Exercise | $2.09 | 3,000 | 6,270 | 3,000 | Jan 03, 2014, 05:49 PM |
| Bain Linda | VP, Fin. & Business Operations | Jan 03, 2014 | Option Exercise | $2.09 | 2,000 | 4,180 | 2,000 | Jan 03, 2014, 05:49 PM |
| Bain Linda | VP, Fin. & Business Operations | Jan 02, 2014 | Sale | $20.83 | 3,000 | 62,490 | 0 | Jan 03, 2014, 05:49 PM |
| Bain Linda | VP, Fin. & Business Operations | Jan 03, 2014 | Sale | $20.99 | 2,000 | 41,980 | 0 | Jan 03, 2014, 05:49 PM |
| Finer Mitchell H. | Chief Scientific Officer | Dec 16, 2013 | Option Exercise | $0.95 | 18,000 | 17,100 | 18,000 | Dec 18, 2013, 05:12 PM |
| Finer Mitchell H. | Chief Scientific Officer | Dec 16, 2013 | Sale | $20.65 | 18,000 | 371,700 | 0 | Dec 18, 2013, 05:12 PM |
| Davidson David | Chief Medical Officer | Dec 16, 2013 | Option Exercise | $2.09 | 15,000 | 31,350 | 15,000 | Dec 18, 2013, 05:12 PM |
| Davidson David | Chief Medical Officer | Dec 16, 2013 | Sale | $20.65 | 15,000 | 309,750 | 0 | Dec 18, 2013, 05:12 PM |
| Bain Linda | VP, Fin. & Business Operations | Dec 16, 2013 | Option Exercise | $2.09 | 2,000 | 4,180 | 2,000 | Dec 18, 2013, 05:11 PM |
| Bain Linda | VP, Fin. & Business Operations | Dec 16, 2013 | Sale | $20.65 | 2,000 | 41,300 | 0 | Dec 18, 2013, 05:11 PM |
Load More Insider Transactions
Buy
Sale
Option Exercise
| Owner | Relationship | Date | Value($) |
| Klima Thomas J | See Remarks | 09/05/2023 | 3,493 |
| Obenshain Andrew | President and CEO | 08/10/2023 | 59,956 |
| Klima Thomas J | See Remarks | 06/02/2023 | 14,451 |
| Leiderman Elisabeth | Director | 10/17/2022 | 6,490 |
| Klima Thomas J | See Remarks | 02/01/2023 | 14,419 |
| Colvin Richard A | Chief Medical Officer | 02/01/2023 | 7,356 |
| Obenshain Andrew | President and CEO | 02/01/2023 | 9,060 |
| Obenshain Andrew | President and CEO | 01/11/2023 | 24,802 |
| Colvin Richard A | Chief Medical Officer | 01/11/2023 | 4,347 |
| Leschly Nick | Director | 01/11/2023 | 33,480 |
| Colvin Richard A | Chief Medical Officer | 11/04/2022 | 1,398 |
| Obenshain Andrew | President and CEO | 11/04/2022 | 8,101 |
| Cole Jason | Chief Strategy & Financial Off | 08/19/2022 | 78,473 |
| Cole Jason | Chief Strategy & Financial Off | 08/04/2022 | 32,707 |
| Obenshain Andrew | President and CEO | 08/04/2022 | 95,754 |
| Eggimann Anne-Virginie | Chief Regulatory Officer | 07/12/2022 | 6,722 |
| Klima Thomas J | Chief Commercial Officer | 06/03/2022 | 11,535 |
| Whitten Jessica | Chief Accounting Officer | 01/11/2022 | 2,690 |
| Whitten Jessica | Chief Accounting Officer | 01/10/2022 | 1,222 |
| Cole Jason | Chief Operating and | 01/11/2022 | 32,659 |
| Cole Jason | Chief Operating and | 01/10/2022 | 14,893 |
| Leschly Nick | Director | 01/11/2022 | 48,869 |
| Leschly Nick | Director | 01/10/2022 | 22,274 |
| Obenshain Andrew | President and CEO | 01/11/2022 | 45,156 |
| Obenshain Andrew | President and CEO | 01/10/2022 | 28,467 |
| Whitten Jessica | Chief Accounting Officer | 01/05/2022 | 31,143 |
| Obenshain Andrew | President and CEO | 12/07/2021 | 8,469 |
| Obenshain Andrew | President of SGD | 04/05/2021 | 876 |
| Gregory Philip D | Chief Scientific Officer | 04/05/2021 | 1,178 |
| Cole Jason | Chief Operating and | 04/05/2021 | 1,118 |
| Leschly Nick | President and CEO | 03/04/2021 | 1,118,534 |
| Leschly Nick | President and CEO | 03/02/2021 | 13,134 |
| Obenshain Andrew | President of SGD | 03/02/2021 | 1,006 |
| Davidson David | Chief Medical Officer | 03/02/2021 | 1,242 |
| Cole Jason | Chief Operating and | 03/02/2021 | 1,124 |
| Gregory Philip D | Chief Scientific Officer | 03/02/2021 | 1,154 |
| Baird William D III | Chief Financial Officer | 02/17/2021 | 19,516 |
| Burnett Katy | Principal Accounting Officer | 02/17/2021 | 14,588 |
| Gregory Philip D | Chief Scientific Officer | 02/17/2021 | 18,699 |
| Obenshain Andrew | President of SGD | 02/17/2021 | 21,093 |
| Davidson David | Chief Medical Officer | 02/17/2021 | 19,657 |
| Cole Jason | Chief Operating and | 02/17/2021 | 18,727 |
| Baird William D III | Chief Financial Officer | 02/12/2021 | 55,352 |
| Obenshain Andrew | President of SGD | 02/02/2021 | 1,561 |
| Davidson David | Chief Medical Officer | 02/02/2021 | 2,893 |
| Leschly Nick | President and CEO | 02/02/2021 | 27,280 |
| Cole Jason | Chief Operating and | 02/02/2021 | 1,745 |
| Gregory Philip D | Chief Scientific Officer | 02/02/2021 | 2,710 |
| Leschly Nick | President and CEO | 01/06/2021 | 454,814 |
| Leschly Nick | President and CEO | 01/05/2021 | 14,969 |
| Baird William D III | Chief Financial Officer | 01/06/2021 | 42,756 |
| FINGER ALISON CECILY | Chief Commercial Officer | 01/06/2021 | 81,727 |
| FINGER ALISON CECILY | Chief Commercial Officer | 01/05/2021 | 1,798 |
| Davidson David | Chief Medical Officer | 01/06/2021 | 142,684 |
| Davidson David | Chief Medical Officer | 01/05/2021 | 2,158 |
| Cole Jason | Chief Operating and | 01/06/2021 | 106,236 |
| Cole Jason | Chief Operating and | 01/05/2021 | 1,933 |
| Smith-Farrell Joanne | COO, Oncology | 01/06/2021 | 57,984 |
| Smith-Farrell Joanne | COO, Oncology | 01/05/2021 | 1,888 |
| Gregory Philip D | Chief Scientific Officer | 01/06/2021 | 124,077 |
| Gregory Philip D | Chief Scientific Officer | 01/05/2021 | 2,023 |
| Burnett Katy | Principal Accounting Officer | 12/03/2020 | 5,669 |
| FINGER ALISON CECILY | Chief Commercial Officer | 12/02/2020 | 1,663 |
| Smith-Farrell Joanne | COO, Oncology | 12/02/2020 | 1,756 |
| Cole Jason | Chief Operating and | 12/02/2020 | 1,756 |
| Gregory Philip D | Chief Scientific Officer | 12/02/2020 | 2,726 |
| Davidson David | Chief Medical Officer | 12/02/2020 | 2,957 |
| Leschly Nick | President and CEO | 12/02/2020 | 20,512 |
| FINGER ALISON CECILY | Chief Commercial Officer | 11/02/2020 | 1,855 |
| Smith-Farrell Joanne | COO, Oncology | 11/02/2020 | 1,960 |
| Cole Jason | Chief Operating and | 11/02/2020 | 1,960 |
| Gregory Philip D | Chief Scientific Officer | 11/02/2020 | 3,123 |
| Davidson David | Chief Medical Officer | 11/02/2020 | 3,335 |
| Leschly Nick | President and CEO | 11/02/2020 | 23,506 |
| Davidson David | Chief Medical Officer | 10/02/2020 | 3,377 |
| Cole Jason | Chief Operating and | 10/02/2020 | 2,005 |
| Smith-Farrell Joanne | Chief Business Officer | 10/02/2020 | 2,005 |
| FINGER ALISON CECILY | Chief Commercial Officer | 10/02/2020 | 1,900 |
| Leschly Nick | President and CEO | 10/02/2020 | 23,744 |
| Gregory Philip D | Chief Scientific Officer | 10/02/2020 | 3,166 |
| FINGER ALISON CECILY | Chief Commercial Officer | 09/03/2020 | 2,051 |
| Smith-Farrell Joanne | Chief Business Officer | 09/03/2020 | 2,110 |
| Cole Jason | Chief Operating and | 09/03/2020 | 2,110 |
| Gregory Philip D | Chief Scientific Officer | 09/03/2020 | 3,399 |
| Davidson David | Chief Medical Officer | 09/03/2020 | 2,403 |
| Leschly Nick | President and CEO | 09/03/2020 | 25,257 |
| Smith-Farrell Joanne | Chief Business Officer | 08/25/2020 | 13,264 |
| WENTWORTH KORY JAMES | Principal Accounting Officer | 08/03/2020 | 5,002 |
| Davidson David | Chief Medical Officer | 08/03/2020 | 2,552 |
| Leschly Nick | President and CEO | 08/03/2020 | 26,856 |
| Cole Jason | Chief Operating and | 08/03/2020 | 2,238 |
| Smith-Farrell Joanne | Chief Business Officer | 08/03/2020 | 2,238 |
| FINGER ALISON CECILY | Chief Commercial Officer | 08/03/2020 | 2,117 |
| Gregory Philip D | Chief Scientific Officer | 08/03/2020 | 3,569 |
| WENTWORTH KORY JAMES | Principal Accounting Officer | 07/20/2020 | 39,562 |
| Davidson David | Chief Medical Officer | 07/02/2020 | 2,586 |
| Leschly Nick | President and CEO | 07/02/2020 | 27,277 |
| Cole Jason | Chief Operating and | 07/02/2020 | 2,340 |
| Smith-Farrell Joanne | Chief Business Officer | 07/02/2020 | 2,340 |
| FINGER ALISON CECILY | Chief Commercial Officer | 07/02/2020 | 2,217 |
| Gregory Philip D | Chief Scientific Officer | 07/02/2020 | 3,633 |
| WENTWORTH KORY JAMES | Principal Accounting Officer | 06/04/2020 | 10,045 |
| Smith-Farrell Joanne | Chief Business Officer | 06/04/2020 | 11,089 |
| Smith-Farrell Joanne | Chief Business Officer | 06/02/2020 | 2,369 |
| Cole Jason | Chief Operating and | 06/02/2020 | 2,433 |
| Davidson David | Chief Medical Officer | 06/02/2020 | 2,689 |
| Leschly Nick | President and CEO | 06/02/2020 | 28,433 |
| FINGER ALISON CECILY | Chief Commercial Officer | 06/02/2020 | 2,241 |
| Gregory Philip D | Chief Scientific Officer | 06/02/2020 | 3,778 |
| Smith-Farrell Joanne | Chief Business Officer | 05/04/2020 | 11,639 |
| Smith-Farrell Joanne | Chief Business Officer | 04/06/2020 | 25,495 |
| Baird William D III | Chief Financial Officer | 02/13/2020 | 113,612 |
| Gregory Philip D | Chief Scientific Officer | 01/10/2020 | 30,306 |
| Gregory Philip D | Chief Scientific Officer | 01/10/2020 | 56,416 |
| Smith-Farrell Joanne | Chief Business Officer | 01/07/2020 | 36,708 |
| WENTWORTH KORY JAMES | Principal Accounting Officer | 01/07/2020 | 20,064 |
| FINGER ALISON CECILY | Chief Commercial Officer | 01/07/2020 | 94,380 |
| Cole Jason | Chief Operating and | 01/07/2020 | 176,074 |
| Davidson David | Chief Medical Officer | 01/07/2020 | 296,635 |
| Gregory Philip D | Chief Scientific Officer | 01/07/2020 | 371,941 |
| Leschly Nick | President and CEO | 01/07/2020 | 914,377 |
| Gregory Philip D | Chief Scientific Officer | 01/06/2020 | 21,665 |
| FINGER ALISON CECILY | Chief Commercial Officer | 01/03/2020 | 43,924 |
| WENTWORTH KORY JAMES | Principal Accounting Officer | 12/19/2019 | 36,758 |
| Gregory Philip D | Chief Scientific Officer | 12/17/2019 | 90,918 |
| Gregory Philip D | Chief Scientific Officer | 12/17/2019 | 169,749 |
| Gregory Philip D | Chief Scientific Officer | 12/05/2019 | 20,142 |
| Gregory Philip D | Chief Scientific Officer | 11/05/2019 | 20,488 |
| Gregory Philip D | Chief Scientific Officer | 10/07/2019 | 22,267 |
| Davidson David | Chief Medical Officer | 09/09/2019 | 151,530 |
| Davidson David | Chief Medical Officer | 09/10/2019 | 104,051 |
| Davidson David | Chief Medical Officer | 09/09/2019 | 300,339 |
| Davidson David | Chief Medical Officer | 09/10/2019 | 206,323 |
| Gregory Philip D | Chief Scientific Officer | 09/05/2019 | 30,306 |
| Gregory Philip D | Chief Scientific Officer | 09/05/2019 | 86,018 |
| Walsh Jeffrey T. | Chief Strategy Officer | 08/20/2019 | 12,235 |
| Walsh Jeffrey T. | Chief Strategy Officer | 08/20/2019 | 62,000 |
| Gregory Philip D | Chief Scientific Officer | 08/08/2019 | 52,920 |
| Gregory Philip D | Chief Scientific Officer | 08/08/2019 | 117,824 |
| Davidson David | Chief Medical Officer | 08/06/2019 | 255,581 |
| Davidson David | Chief Medical Officer | 08/06/2019 | 587,388 |
| Gregory Philip D | Chief Scientific Officer | 08/05/2019 | 30,306 |
| Gregory Philip D | Chief Scientific Officer | 08/05/2019 | 99,393 |
| Gregory Philip D | Chief Scientific Officer | 07/05/2019 | 83,226 |
| Gregory Philip D | Chief Scientific Officer | 07/05/2019 | 232,427 |
| Davidson David | Chief Medical Officer | 07/05/2019 | 372,053 |
| Davidson David | Chief Medical Officer | 07/05/2019 | 991,746 |
| Walsh Jeffrey T. | Chief Strategy Officer | 06/18/2019 | 2,447 |
| Walsh Jeffrey T. | Chief Strategy Officer | 06/18/2019 | 12,612 |
| Walsh Jeffrey T. | Chief Strategy Officer | 06/10/2019 | 34,258 |
| Walsh Jeffrey T. | Chief Strategy Officer | 06/10/2019 | 175,619 |
| Davidson David | Chief Medical Officer | 06/06/2019 | 255,581 |
| Davidson David | Chief Medical Officer | 06/06/2019 | 620,539 |
| WENTWORTH KORY JAMES | Principal Accounting Officer | 06/05/2019 | 7,784 |
| Gregory Philip D | Chief Scientific Officer | 06/05/2019 | 83,226 |
| Gregory Philip D | Chief Scientific Officer | 06/05/2019 | 231,489 |
| Walsh Jeffrey T. | Chief Strategy Officer | 05/10/2019 | 36,705 |
| Walsh Jeffrey T. | Chief Strategy Officer | 05/10/2019 | 198,451 |
| Cole Jason | Chief Operating and | 05/10/2019 | 28,387 |
| Gregory Philip D | Chief Scientific Officer | 05/06/2019 | 83,226 |
| Gregory Philip D | Chief Scientific Officer | 05/06/2019 | 249,184 |
| Davidson David | Chief Medical Officer | 05/06/2019 | 34,983 |
| Davidson David | Chief Medical Officer | 05/06/2019 | 883,718 |
| Walsh Jeffrey T. | Chief Strategy Officer | 04/10/2019 | 36,705 |
| Walsh Jeffrey T. | Chief Strategy Officer | 04/10/2019 | 234,976 |
| Gregory Philip D | Chief Scientific Officer | 04/05/2019 | 83,226 |
| Gregory Philip D | Chief Scientific Officer | 04/05/2019 | 283,682 |
| Davidson David | Chief Medical Officer | 04/04/2019 | 34,983 |
| Davidson David | Chief Medical Officer | 04/04/2019 | 1,017,976 |
| Davidson David | Chief Medical Officer | 03/13/2019 | 17,057 |
| Davidson David | Chief Medical Officer | 03/13/2019 | 454,004 |
| Walsh Jeffrey T. | Chief Strategy Officer | 03/11/2019 | 36,705 |
| Walsh Jeffrey T. | Chief Strategy Officer | 03/11/2019 | 209,698 |
| Gregory Philip D | Chief Scientific Officer | 03/05/2019 | 83,226 |
| Gregory Philip D | Chief Scientific Officer | 03/05/2019 | 265,879 |
| Davidson David | Chief Medical Officer | 03/04/2019 | 248,004 |
| Davidson David | Chief Medical Officer | 03/04/2019 | 764,833 |
| WENTWORTH KORY JAMES | Principal Accounting Officer | 02/28/2019 | 7,737 |
| Cole Jason | Chief Operating and | 02/25/2019 | 252,687 |
| Cole Jason | Chief Operating and | 02/25/2019 | 938,697 |
| WENTWORTH KORY JAMES | Principal Accounting Officer | 02/25/2019 | 31,201 |
| Walsh Jeffrey T. | Chief Financial and | 02/08/2019 | 36,705 |
| Walsh Jeffrey T. | Chief Financial and | 02/08/2019 | 196,928 |
| Gregory Philip D | Chief Scientific Officer | 02/05/2019 | 83,226 |
| Gregory Philip D | Chief Scientific Officer | 02/05/2019 | 248,383 |
| Davidson David | Chief Medical Officer | 02/04/2019 | 155,432 |
| Davidson David | Chief Medical Officer | 02/04/2019 | 659,416 |
| WENTWORTH KORY JAMES | Principal Accounting Officer | 01/28/2019 | 26,326 |
| Davidson David | Chief Medical Officer | 01/18/2019 | 49,796 |
| Davidson David | Chief Medical Officer | 01/18/2019 | 264,644 |
| Walsh Jeffrey T. | Chief Financial | 01/16/2019 | 73,410 |
| Walsh Jeffrey T. | Chief Financial | 01/16/2019 | 375,429 |
| Gregory Philip D | Chief Scientific Officer | 01/16/2019 | 105,840 |
| Gregory Philip D | Chief Scientific Officer | 01/16/2019 | 236,069 |
| Walsh Jeffrey T. | Chief Financial | 01/07/2019 | 342,277 |
| Leschly Nick | President and CEO | 01/07/2019 | 837,965 |
| Gregory Philip D | Chief Scientific Officer | 01/07/2019 | 30,306 |
| Gregory Philip D | Chief Scientific Officer | 01/07/2019 | 436,363 |
| FINGER ALISON CECILY | Chief Commercial Officer | 01/07/2019 | 73,068 |
| FINGER ALISON CECILY | Chief Commercial Officer | 01/03/2019 | 47,273 |
| Davidson David | Chief Medical Officer | 01/07/2019 | 302,733 |
| Cole Jason | Chief Legal Officer | 01/07/2019 | 160,914 |
| FINGER ALISON CECILY | Chief Commercial Officer | 01/03/2019 | 42,506 |
| Davidson David | Chief Medical Officer | 01/03/2019 | 2,447 |
| Davidson David | Chief Medical Officer | 01/02/2019 | 130,410 |
| Davidson David | Chief Medical Officer | 01/03/2019 | 10,032 |
| Davidson David | Chief Medical Officer | 01/02/2019 | 741,027 |
| WENTWORTH KORY JAMES | Principal Accounting Officer | 12/19/2018 | 39,983 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 12/06/2018 | 1,030 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 12/06/2018 | 198,198 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 12/06/2018 | 198,198 |
| Gregory Philip D | Chief Scientific Officer | 12/06/2018 | 30,306 |
| Gregory Philip D | Chief Scientific Officer | 12/06/2018 | 90,577 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 12/03/2018 | 215,135 |
| Davidson David | Chief Medical Officer | 12/04/2018 | 11,001 |
| Davidson David | Chief Medical Officer | 12/03/2018 | 33,002 |
| Davidson David | Chief Medical Officer | 12/03/2018 | 681,540 |
| Davidson David | Chief Medical Officer | 12/04/2018 | 242,108 |
| Walsh Jeffrey T. | Chief Financial | 11/09/2018 | 36,705 |
| Walsh Jeffrey T. | Chief Financial | 11/09/2018 | 195,890 |
| Gregory Philip D | Chief Scientific Officer | 11/05/2018 | 83,226 |
| Gregory Philip D | Chief Scientific Officer | 11/05/2018 | 247,277 |
| Davidson David | Chief Medical Officer | 11/02/2018 | 27,502 |
| Davidson David | Chief Medical Officer | 11/02/2018 | 668,216 |
| Walsh Jeffrey T. | Chief Financial | 10/10/2018 | 36,705 |
| Walsh Jeffrey T. | Chief Financial | 10/10/2018 | 202,839 |
| Gregory Philip D | Chief Scientific Officer | 10/05/2018 | 83,226 |
| Gregory Philip D | Chief Scientific Officer | 10/05/2018 | 253,001 |
| Davidson David | Chief Medical Officer | 10/02/2018 | 27,502 |
| Davidson David | Chief Medical Officer | 10/02/2018 | 696,588 |
| Walsh Jeffrey T. | Chief Financial | 09/10/2018 | 36,705 |
| Mandell James | Director | 09/10/2018 | 150,771 |
| Walsh Jeffrey T. | Chief Financial | 09/10/2018 | 225,243 |
| Gregory Philip D | Chief Scientific Officer | 09/05/2018 | 83,226 |
| Gregory Philip D | Chief Scientific Officer | 09/05/2018 | 293,441 |
| Davidson David | Chief Medical Officer | 09/04/2018 | 38,503 |
| Davidson David | Chief Medical Officer | 09/04/2018 | 1,166,493 |
| Walsh Jeffrey T. | Chief Financial | 08/30/2018 | 217,689 |
| Walsh Jeffrey T. | Chief Financial | 08/30/2018 | 3,507,948 |
| FINGER ALISON CECILY | Chief Commercial Officer | 08/20/2018 | 40,940 |
| Walsh Jeffrey T. | Chief Financial | 08/10/2018 | 8,251 |
| Walsh Jeffrey T. | Chief Financial | 08/10/2018 | 235,389 |
| Cole Jason | Chief Legal Officer | 08/08/2018 | 99,988 |
| Gregory Philip D | Chief Scientific Officer | 08/06/2018 | 83,226 |
| Gregory Philip D | Chief Scientific Officer | 08/06/2018 | 281,889 |
| Walsh Jeffrey T. | Chief Financial | 08/02/2018 | 118,259 |
| Walsh Jeffrey T. | Chief Financial | 08/02/2018 | 3,268,495 |
| Davidson David | Chief Medical Officer | 08/02/2018 | 38,503 |
| Davidson David | Chief Medical Officer | 08/02/2018 | 1,052,583 |
| Gregory Philip D | Chief Scientific Officer | 06/18/2018 | 695,978 |
| Davidson David | Chief Medical Officer | 07/11/2018 | 16,501 |
| Davidson David | Chief Medical Officer | 07/11/2018 | 540,444 |
| Cole Jason | Chief Legal Officer | 07/09/2018 | 872,715 |
| Davidson David | Chief Medical Officer | 07/02/2018 | 55,004 |
| Davidson David | Chief Medical Officer | 07/02/2018 | 1,539,601 |
| Gregory Philip D | Chief Scientific Officer | 06/18/2018 | 695,978 |
| Vachon Mark | Director | 06/14/2018 | 189,992 |
| Vachon Mark | Director | 06/04/2018 | 252,420 |
| Vachon Mark | Director | 06/04/2018 | 1,129,302 |
| Davidson David | Chief Medical Officer | 06/04/2018 | 318,110 |
| Davidson David | Chief Medical Officer | 06/04/2018 | 2,441,965 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 06/04/2018 | 240,275 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 06/04/2018 | 696,892 |
| Cole Jason | Chief Legal Officer | 05/04/2018 | 640,849 |
| Davidson David | Chief Medical Officer | 05/02/2018 | 318,110 |
| Davidson David | Chief Medical Officer | 05/02/2018 | 2,307,697 |
| Davidson David | Chief Medical Officer | 04/12/2018 | 73,410 |
| Davidson David | Chief Medical Officer | 04/12/2018 | 540,507 |
| Gregory Philip D | Chief Scientific Officer | 04/02/2018 | 63,137 |
| Gregory Philip D | Chief Scientific Officer | 04/02/2018 | 379,608 |
| Davidson David | Chief Medical Officer | 04/02/2018 | 538,340 |
| Davidson David | Chief Medical Officer | 04/02/2018 | 3,685,383 |
| Vachon Mark | Director | 03/15/2018 | 182,820 |
| Vachon Mark | Director | 03/15/2018 | 1,286,249 |
| Davidson David | Chief Medical Officer | 03/02/2018 | 22,002 |
| Davidson David | Chief Medical Officer | 03/02/2018 | 804,751 |
| Gregory Philip D | Chief Scientific Officer | 03/01/2018 | 63,137 |
| Gregory Philip D | Chief Scientific Officer | 03/01/2018 | 449,996 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 02/28/2018 | 71,671 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 02/28/2018 | 211,592 |
| Gregory Philip D | Chief Scientific Officer | 02/01/2018 | 63,137 |
| Gregory Philip D | Chief Scientific Officer | 02/01/2018 | 461,020 |
| Davidson David | Chief Medical Officer | 02/02/2018 | 22,002 |
| Davidson David | Chief Medical Officer | 02/02/2018 | 809,440 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 01/30/2018 | 1,015,608 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 01/30/2018 | 3,381,791 |
| Cole Jason | Chief Legal Officer | 01/30/2018 | 563,250 |
| Cole Jason | Chief Legal Officer | 01/30/2018 | 4,897,744 |
| Walsh Jeffrey T. | Chief Financial | 01/05/2018 | 530,530 |
| Leschly Nick | President and CEO | 01/05/2018 | 942,297 |
| Gregory Philip D | Chief Scientific Officer | 01/05/2018 | 296,820 |
| Davidson David | Chief Medical Officer | 01/08/2018 | 6,600 |
| Davidson David | Chief Medical Officer | 01/08/2018 | 208,883 |
| Davidson David | Chief Medical Officer | 01/05/2018 | 402,578 |
| Cole Jason | Chief Legal Officer | 01/05/2018 | 195,742 |
| Gregory Philip D | Chief Scientific Officer | 01/03/2018 | 63,137 |
| Gregory Philip D | Chief Scientific Officer | 01/03/2018 | 406,550 |
| Davidson David | Chief Medical Officer | 01/03/2018 | 33,002 |
| Davidson David | Chief Medical Officer | 01/03/2018 | 1,081,781 |
| Leschly Nick | President and CEO | 12/13/2017 | 208,317 |
| Leschly Nick | President and CEO | 12/13/2017 | 21,629,112 |
| Vachon Mark | Director | 12/11/2017 | 182,820 |
| Vachon Mark | Director | 12/11/2017 | 1,516,466 |
| Walsh Jeffrey T. | Chief Financial | 12/11/2017 | 242,253 |
| Walsh Jeffrey T. | Chief Financial | 12/11/2017 | 2,143,785 |
| HIGH SUSANNA GATTI | Chief Operating Officer | 12/01/2017 | 220,696 |
| Gregory Philip D | Chief Scientific Officer | 12/01/2017 | 63,137 |
| Gregory Philip D | Chief Scientific Officer | 12/01/2017 | 388,211 |
| Davidson David | Chief Medical Officer | 12/01/2017 | 22,002 |
| Davidson David | Chief Medical Officer | 12/01/2017 | 689,680 |
| Walsh Jeffrey T. | Chief Financial | 11/10/2017 | 197,870 |
| Walsh Jeffrey T. | Chief Financial | 11/10/2017 | 1,480,863 |
| Walsh Jeffrey T. | Chief Financial | 11/01/2017 | 192,514 |
| Walsh Jeffrey T. | Chief Financial | 11/01/2017 | 5,298,331 |
| Leschly Nick | President and CEO | 11/01/2017 | 11,699 |
| Leschly Nick | President and CEO | 11/01/2017 | 308,779 |
| Gregory Philip D | Chief Scientific Officer | 11/01/2017 | 63,137 |
| Gregory Philip D | Chief Scientific Officer | 11/01/2017 | 324,690 |
| Davidson David | Chief Medical Officer | 11/01/2017 | 22,002 |
| Davidson David | Chief Medical Officer | 11/01/2017 | 580,821 |
| Leschly Nick | President and CEO | 10/23/2017 | 537,455 |
| Leschly Nick | President and CEO | 10/20/2017 | 485,814 |
| Leschly Nick | President and CEO | 10/17/2017 | 1,569,844 |
| Walsh Jeffrey T. | Chief Financial | 10/10/2017 | 26,952 |
| Walsh Jeffrey T. | Chief Financial | 10/10/2017 | 636,724 |
| Gregory Philip D | Chief Scientific Officer | 10/02/2017 | 63,137 |
| Gregory Philip D | Chief Scientific Officer | 10/02/2017 | 296,603 |
| Davidson David | Chief Medical Officer | 10/02/2017 | 22,002 |
| Davidson David | Chief Medical Officer | 10/02/2017 | 525,248 |
| MARAGANORE JOHN | Director | 09/14/2017 | 39,434 |
| MARAGANORE JOHN | Director | 09/14/2017 | 2,475,724 |
| Vachon Mark | Director | 09/12/2017 | 182,820 |
| Vachon Mark | Director | 09/12/2017 | 760,921 |
| Walsh Jeffrey T. | Chief Financial | 09/11/2017 | 26,952 |
| Walsh Jeffrey T. | Chief Financial | 09/11/2017 | 616,065 |
| Gregory Philip D | Chief Scientific Officer | 09/01/2017 | 63,137 |
| Gregory Philip D | Chief Scientific Officer | 09/01/2017 | 283,635 |
| Davidson David | Chief Medical Officer | 09/01/2017 | 66,005 |
| Davidson David | Chief Medical Officer | 09/01/2017 | 1,548,901 |
| Walsh Jeffrey T. | Chief Financial | 08/31/2017 | 66,005 |
| Walsh Jeffrey T. | Chief Financial | 08/31/2017 | 1,500,096 |
| Schenkein David P | Director | 08/31/2017 | 16,312 |
| Schenkein David P | Director | 08/31/2017 | 230,146 |
| LYNCH DANIEL | Director | 08/31/2017 | 2,750 |
| LYNCH DANIEL | Director | 08/31/2017 | 60,000 |
| Leschly Nick | President and CEO | 09/01/2017 | 35,005 |
| Leschly Nick | President and CEO | 08/31/2017 | 2,800,461 |
| Leschly Nick | President and CEO | 09/01/2017 | 2,925,990 |
| Leschly Nick | President and CEO | 08/30/2017 | 2,956,299 |
| Walsh Jeffrey T. | Chief Financial | 08/28/2017 | 6,876 |
| Walsh Jeffrey T. | Chief Financial | 08/28/2017 | 133,826 |
| MARAGANORE JOHN | Director | 08/24/2017 | 28,924 |
| MARAGANORE JOHN | Director | 08/02/2017 | 266,425 |
| MARAGANORE JOHN | Director | 08/24/2017 | 1,062,108 |
| Mandell James | Director | 08/14/2017 | 95,950 |
| Walsh Jeffrey T. | Chief Financial | 08/10/2017 | 6,876 |
| Walsh Jeffrey T. | Chief Financial | 08/10/2017 | 119,265 |
| Gregory Philip D | Chief Scientific Officer | 08/07/2017 | 25,255 |
| Gregory Philip D | Chief Scientific Officer | 08/07/2017 | 74,250 |
| Sullivan Eric | Principal Accounting Officer | 08/04/2017 | 23,890 |
| Sullivan Eric | Principal Accounting Officer | 08/03/2017 | 9,237 |
| Sullivan Eric | Principal Accounting Officer | 08/04/2017 | 42,370 |
| Sullivan Eric | Principal Accounting Officer | 08/03/2017 | 38,418 |
| Gregory Philip D | Chief Scientific Officer | 08/01/2017 | 37,882 |
| Gregory Philip D | Chief Scientific Officer | 08/01/2017 | 139,620 |
| Davidson David | Chief Medical Officer</ |