. (AMLN)
$30.98 - (-)
Market Cap: -
As of 09/21/12 12:00 AM EDT. Market closed.
. (AMLN)
$30.98
- (-)
Market Cap: -
As of 09/21/12 12:00 AM EDT. Market closed.
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52 week range
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INSIDER TRANSACTIONS FOR
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | Aug 08, 2012 | Option Exercise | $31.00 | 7,974 | 247,194 | 1,360 | Aug 10, 2012, 06:39 PM |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | Aug 08, 2012 | Option Exercise | $31.00 | 3,665 | 113,615 | 3,192 | Aug 10, 2012, 06:39 PM |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | Aug 08, 2012 | Option Exercise | $31.00 | 35,426 | 1,098,206 | 35,014 | Aug 10, 2012, 06:39 PM |
| FOLETTA MARK G | SVP, Chief Financial Officer | Aug 08, 2012 | Option Exercise | $31.00 | 129,404 | 4,011,524 | 138,072 | Aug 10, 2012, 06:39 PM |
| FOLETTA MARK G | SVP, Chief Financial Officer | Aug 08, 2012 | Option Exercise | $31.00 | 110 | 3,410 | 0 | Aug 10, 2012, 06:39 PM |
| FOLETTA MARK G | SVP, Chief Financial Officer | Aug 08, 2012 | Option Exercise | $31.00 | 7,974 | 247,194 | 2,889 | Aug 10, 2012, 06:39 PM |
| FOLETTA MARK G | SVP, Chief Financial Officer | Aug 08, 2012 | Option Exercise | $31.00 | 3,868 | 119,908 | 3,415 | Aug 10, 2012, 06:39 PM |
| FOLETTA MARK G | SVP, Chief Financial Officer | Aug 08, 2012 | Option Exercise | $31.00 | 73,370 | 2,274,470 | 129,817 | Aug 10, 2012, 06:39 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Aug 08, 2012 | Option Exercise | $31.00 | 431,052 | 13,362,612 | 313,471 | Aug 10, 2012, 06:39 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Aug 08, 2012 | Option Exercise | $31.00 | 23,923 | 741,613 | 14,460 | Aug 10, 2012, 06:39 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Aug 08, 2012 | Option Exercise | $31.00 | 36,931 | 1,144,861 | 0 | Aug 10, 2012, 06:39 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Aug 08, 2012 | Option Exercise | $31.00 | 7,974 | 247,194 | 4,519 | Aug 10, 2012, 06:39 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Aug 08, 2012 | Option Exercise | $31.00 | 13,456 | 417,136 | 13,003 | Aug 10, 2012, 06:39 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Aug 08, 2012 | Option Exercise | $31.00 | 42,897 | 1,329,807 | 0 | Aug 10, 2012, 06:39 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Aug 08, 2012 | Option Exercise | $31.00 | 97,945 | 3,036,295 | 3,327 | Aug 10, 2012, 06:39 PM |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | Aug 08, 2012 | Option Exercise | $31.00 | 7,974 | 247,194 | 1,360 | Aug 10, 2012, 06:38 PM |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | Aug 08, 2012 | Option Exercise | $31.00 | 2,087 | 64,697 | 1,161 | Aug 10, 2012, 06:38 PM |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | Aug 08, 2012 | Option Exercise | $31.00 | 62,469 | 1,936,539 | 412 | Aug 10, 2012, 06:38 PM |
| LEONHARDT HARRY J | SVP, Legal, Compl & Corp Secty | Aug 08, 2012 | Option Exercise | $31.00 | 7,386 | 228,966 | 4,227 | Aug 10, 2012, 06:38 PM |
| LEONHARDT HARRY J | SVP, Legal, Compl & Corp Secty | Aug 08, 2012 | Option Exercise | $31.00 | 727 | 22,537 | 0 | Aug 10, 2012, 06:38 PM |
| LEONHARDT HARRY J | SVP, Legal, Compl & Corp Secty | Aug 08, 2012 | Option Exercise | $31.00 | 38,706 | 1,199,886 | 6,361 | Aug 10, 2012, 06:38 PM |
| Marshall Paul | SVP, Operations | Aug 08, 2012 | Option Exercise | $31.00 | 2,105 | 65,255 | 473 | Aug 10, 2012, 06:38 PM |
| Marshall Paul | SVP, Operations | Aug 08, 2012 | Option Exercise | $31.00 | 31,723 | 983,413 | 0 | Aug 10, 2012, 06:38 PM |
| Marshall Paul | SVP, Operations | Aug 08, 2012 | Option Exercise | $31.00 | 7,974 | 247,194 | 2,990 | Aug 10, 2012, 06:38 PM |
| Mihalik Vincent P | SVP, Chief Commercial Officer | Aug 08, 2012 | Option Exercise | $31.00 | 4,519 | 140,089 | 2,720 | Aug 10, 2012, 06:38 PM |
| Mihalik Vincent P | SVP, Chief Commercial Officer | Aug 08, 2012 | Option Exercise | $31.00 | 1,338 | 41,478 | 453 | Aug 10, 2012, 06:38 PM |
| Mihalik Vincent P | SVP, Chief Commercial Officer | Aug 08, 2012 | Option Exercise | $31.00 | 39,917 | 1,237,427 | 0 | Aug 10, 2012, 06:38 PM |
| Weyer Christian | SVP, Research & Development | Aug 08, 2012 | Option Exercise | $31.00 | 359 | 11,129 | 0 | Aug 10, 2012, 06:37 PM |
| Weyer Christian | SVP, Research & Development | Aug 08, 2012 | Option Exercise | $31.00 | 1,339 | 41,509 | 886 | Aug 10, 2012, 06:37 PM |
| Weyer Christian | SVP, Research & Development | Aug 08, 2012 | Option Exercise | $31.00 | 34,207 | 1,060,417 | 1,012 | Aug 10, 2012, 06:37 PM |
| Weyer Christian | SVP, Research & Development | Aug 08, 2012 | Option Exercise | $31.00 | 7,974 | 247,194 | 3,159 | Aug 10, 2012, 06:37 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Aug 08, 2012 | Option Exercise | $31.00 | 142,698 | 4,423,638 | 263,910 | Aug 10, 2012, 06:37 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Aug 08, 2012 | Option Exercise | $31.00 | 12,767 | 395,777 | 0 | Aug 10, 2012, 06:37 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Aug 08, 2012 | Option Exercise | $31.00 | 192,561 | 5,969,391 | 415 | Aug 10, 2012, 06:37 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Aug 08, 2012 | Option Exercise | $31.00 | 7,974 | 247,194 | 2,990 | Aug 10, 2012, 06:37 PM |
| Gergen Mark J | SVP, Corporate Development | Aug 08, 2012 | Option Exercise | $31.00 | 106,362 | 3,297,222 | 53,181 | Aug 10, 2012, 06:37 PM |
| Gergen Mark J | SVP, Corporate Development | Aug 08, 2012 | Option Exercise | $31.00 | 64,750 | 2,007,250 | 412 | Aug 10, 2012, 06:37 PM |
| Gergen Mark J | SVP, Corporate Development | Aug 08, 2012 | Option Exercise | $31.00 | 7,974 | 247,194 | 1,360 | Aug 10, 2012, 06:37 PM |
| Gergen Mark J | SVP, Corporate Development | Aug 08, 2012 | Option Exercise | $31.00 | 2,609 | 80,879 | 473 | Aug 10, 2012, 06:37 PM |
| BECK TERESA | Director | Aug 08, 2012 | Option Exercise | $31.00 | 8,000 | 248,000 | 0 | Aug 10, 2012, 06:36 PM |
| ADAMS ADRIAN | Director | Aug 08, 2012 | Option Exercise | $31.00 | 21,000 | 651,000 | 10,200 | Aug 10, 2012, 06:36 PM |
| EASTHAM KARIN | Director | Aug 08, 2012 | Option Exercise | $31.00 | 6,000 | 186,000 | 0 | Aug 10, 2012, 06:36 PM |
| GAVIN JAMES R III | Director | Aug 08, 2012 | Option Exercise | $31.00 | 4,580 | 141,980 | 0 | Aug 10, 2012, 06:36 PM |
| SULLIVAN JOSEPH P | Director | Aug 08, 2012 | Option Exercise | $31.00 | 6,000 | 186,000 | 0 | Aug 10, 2012, 06:35 PM |
| SKYLER JAY S | Director | Aug 08, 2012 | Option Exercise | $31.00 | 201 | 6,231 | 0 | Aug 10, 2012, 06:35 PM |
| SKYLER JAY S | Director | Aug 08, 2012 | Option Exercise | $31.00 | 23,000 | 713,000 | 0 | Aug 10, 2012, 06:35 PM |
| SKYLER JAY S | Director | Aug 08, 2012 | Option Exercise | $31.00 | 98,286 | 3,046,866 | 0 | Aug 10, 2012, 06:35 PM |
| SKYLER JAY S | Director | Aug 08, 2012 | Option Exercise | $31.00 | 20,000 | 620,000 | 0 | Aug 10, 2012, 06:35 PM |
| SKYLER JAY S | Director | Aug 08, 2012 | Option Exercise | $31.00 | 6,675 | 206,925 | 0 | Aug 10, 2012, 06:35 PM |
| DENNER ALEXANDER J | Director | Aug 08, 2012 | Option Exercise | $31.00 | 10,161 | 314,991 | 1,104 | Aug 10, 2012, 06:35 PM |
| Costa Paulo F | Director | Aug 08, 2012 | Option Exercise | $31.00 | 26,000 | 806,000 | 1,067 | Aug 10, 2012, 06:35 PM |
| BEHRENS M KATHLEEN | Director | Aug 08, 2012 | Option Exercise | $31.00 | 6,000 | 186,000 | 0 | Aug 10, 2012, 06:34 PM |
| Weyer Christian | SVP, Research & Development | Jul 25, 2012 | Option Exercise | $14.62 | 39 | 570 | 34,207 | Jul 26, 2012, 08:07 PM |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | Jul 25, 2012 | Option Exercise | $14.62 | 823 | 12,032 | 35,426 | Jul 26, 2012, 08:06 PM |
| Mihalik Vincent P | SVP, Chief Commercial Officer | Jul 25, 2012 | Option Exercise | $14.62 | 890 | 13,012 | 39,917 | Jul 26, 2012, 08:06 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Jul 25, 2012 | Option Exercise | $14.62 | 1,376 | 20,117 | 185,653 | Jul 26, 2012, 08:06 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Jul 26, 2012 | Option Exercise | $30.80 | 13,392 | 412,407 | 194,338 | Jul 26, 2012, 08:06 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Jul 26, 2012 | Option Exercise | $11.95 | 20,300 | 242,585 | 198,744 | Jul 26, 2012, 08:06 PM |
| Gergen Mark J | SVP, Corporate Development | Jul 25, 2012 | Option Exercise | $14.62 | 936 | 13,684 | 64,750 | Jul 26, 2012, 08:06 PM |
| FOLETTA MARK G | SVP, Chief Financial Officer | Jul 25, 2012 | Option Exercise | $14.62 | 880 | 12,866 | 73,370 | Jul 26, 2012, 08:06 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Jul 26, 2012 | Option Exercise | $30.80 | 24,252 | 746,840 | 103,076 | Jul 26, 2012, 08:05 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Jul 26, 2012 | Option Exercise | $11.95 | 36,000 | 430,200 | 113,779 | Jul 26, 2012, 08:05 PM |
| SKYLER JAY S | Director | May 11, 2012 | Option Exercise | $9.29 | 18,000 | 167,280 | 95,286 | May 14, 2012, 06:30 PM |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | Mar 28, 2012 | Option Exercise | $9.02 | 5,000 | 45,100 | 42,603 | Mar 29, 2012, 07:17 PM |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | Mar 29, 2012 | Sale | $25.00 | 3,000 | 75,000 | 34,603 | Mar 29, 2012, 07:17 PM |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | Mar 28, 2012 | Sale | $22.83 | 5,000 | 114,150 | 37,603 | Mar 29, 2012, 07:17 PM |
| Weyer Christian | SVP, Research & Development | Mar 01, 2012 | Sale | $17.11 | 1,231 | 21,062 | 24,168 | Mar 02, 2012, 07:47 PM |
| Mihalik Vincent P | SVP, Chief Commercial Officer | Mar 01, 2012 | Sale | $17.11 | 1,231 | 21,062 | 29,027 | Mar 02, 2012, 07:46 PM |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | Mar 01, 2012 | Sale | $17.11 | 1,846 | 31,585 | 52,469 | Mar 02, 2012, 07:46 PM |
| LEONHARDT HARRY J | SVP, Legal, Compliance and Cor | Mar 01, 2012 | Sale | $17.11 | 1,231 | 21,062 | 23,705 | Mar 02, 2012, 07:46 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Mar 01, 2012 | Sale | $17.11 | 1,846 | 31,585 | 174,277 | Mar 02, 2012, 07:46 PM |
| Gergen Mark J | SVP, Corporate Development | Mar 01, 2012 | Sale | $17.11 | 1,846 | 31,585 | 53,814 | Mar 02, 2012, 07:45 PM |
| FOLETTA MARK G | SVP, Chief Financial Officer | Mar 01, 2012 | Sale | $17.11 | 1,846 | 31,585 | 62,490 | Mar 02, 2012, 07:45 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Mar 01, 2012 | Sale | $17.11 | 1,539 | 26,332 | 62,912 | Mar 02, 2012, 07:45 PM |
| Weyer Christian | SVP, Research & Development | Feb 23, 2012 | Sale | $17.03 | 2,519 | 42,899 | 24,597 | Feb 24, 2012, 05:03 PM |
| Mihalik Vincent P | SVP, Chief Commercial Officer | Feb 23, 2012 | Sale | $17.03 | 7,518 | 128,033 | 29,657 | Feb 24, 2012, 05:03 PM |
| Marshall Paul | SVP, Operations | Feb 23, 2012 | Sale | $17.03 | 5,638 | 96,016 | 21,723 | Feb 24, 2012, 05:02 PM |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | Feb 23, 2012 | Sale | $17.03 | 7,518 | 128,033 | 52,043 | Feb 24, 2012, 05:02 PM |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | Feb 08, 2012 | Sale | $16.62 | 5,653 | 93,927 | 39,561 | Feb 24, 2012, 05:02 PM |
| LEONHARDT HARRY J | SVP, Legal, Compliance and Cor | Feb 23, 2012 | Sale | $17.03 | 2,180 | 37,126 | 24,936 | Feb 24, 2012, 05:02 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Feb 23, 2012 | Sale | $17.03 | 5,638 | 96,016 | 175,182 | Feb 24, 2012, 05:02 PM |
| Gergen Mark J | SVP, Corporate Development | Feb 23, 2012 | Sale | $17.03 | 7,518 | 128,033 | 54,826 | Feb 24, 2012, 05:02 PM |
| FOLETTA MARK G | SVP, Chief Financial Officer | Feb 23, 2012 | Sale | $17.03 | 5,638 | 96,016 | 63,439 | Feb 24, 2012, 05:02 PM |
| Weyer Christian | SVP, Research & Development | Feb 08, 2012 | Sale | $16.62 | 3,843 | 63,853 | 20,416 | Feb 10, 2012, 08:55 PM |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | Feb 01, 2012 | Option Exercise | $15.53 | 473 | 7,346 | 2,087 | Feb 10, 2012, 08:55 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Feb 08, 2012 | Sale | $16.62 | 5,637 | 93,661 | 165,820 | Feb 10, 2012, 08:55 PM |
| LEONHARDT HARRY J | SVP, Legal, Compliance and Cor | Feb 08, 2012 | Option Exercise | $16.47 | 2,041 | 33,615 | 19,404 | Feb 10, 2012, 08:54 PM |
| Gergen Mark J | SVP, Corporate Development | Feb 08, 2012 | Option Exercise | $16.47 | 3,133 | 51,601 | 42,344 | Feb 10, 2012, 08:54 PM |
| FOLETTA MARK G | SVP, Chief Financial Officer | Feb 08, 2012 | Option Exercise | $16.47 | 3,122 | 51,419 | 54,565 | Feb 10, 2012, 08:54 PM |
| Marshall Paul | SVP, Operations | Feb 08, 2012 | Option Exercise | $16.47 | 3,139 | 51,699 | 12,361 | Feb 10, 2012, 08:53 PM |
| Mihalik Vincent P | SVP, Chief Commercial Officer | Feb 08, 2012 | Sale | $16.62 | 3,842 | 63,838 | 17,175 | Feb 10, 2012, 08:53 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Jan 18, 2012 | Option Exercise | $11.46 | 4,538 | 52,005 | 20,723 | Jan 19, 2012, 04:45 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Jan 18, 2012 | Option Exercise | $11.46 | 4,538 | 52,005 | 36,483 | Jan 19, 2012, 04:45 PM |
| DENNER ALEXANDER J | Director | Jan 17, 2012 | Sale | $11.59 | 1,832 | 21,233 | 7,161 | Jan 19, 2012, 04:45 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Oct 04, 2011 | Option Exercise | $8.75 | 28,979 | 253,566 | 40,275 | Oct 06, 2011, 05:36 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Oct 04, 2011 | Option Exercise | $5.73 | 45,000 | 257,850 | 60,624 | Oct 06, 2011, 05:36 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Oct 04, 2011 | Option Exercise | $8.75 | 1,636 | 14,315 | 156,457 | Oct 05, 2011, 04:19 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Oct 03, 2011 | Option Exercise | $5.73 | 15,000 | 85,950 | 168,093 | Oct 05, 2011, 04:19 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Oct 04, 2011 | Option Exercise | $5.73 | 2,500 | 14,325 | 158,031 | Oct 05, 2011, 04:19 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Oct 03, 2011 | Sale | $8.75 | 15,000 | 131,224 | 155,593 | Oct 05, 2011, 04:19 PM |
| Costa Paulo F | Director | Aug 19, 2011 | Option Exercise | $9.90 | 10,000 | 98,984 | 23,000 | Aug 19, 2011, 06:28 PM |
| Costa Paulo F | Director | Aug 17, 2011 | Option Exercise | $10.71 | 10,000 | 107,083 | 13,000 | Aug 18, 2011, 05:30 PM |
| ADAMS ADRIAN | Director | Aug 15, 2011 | Option Exercise | $10.74 | 15,000 | 161,095 | 18,000 | Aug 17, 2011, 04:32 PM |
| SKYLER JAY S | Director | May 24, 2011 | Option Exercise | $13.18 | 2,510 | 33,082 | 77,286 | May 25, 2011, 05:05 PM |
| SKYLER JAY S | Director | May 24, 2011 | Option Exercise | $11.03 | 3,000 | 33,090 | 79,796 | May 25, 2011, 05:05 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Mar 01, 2011 | Option Exercise | $10.14 | 13,750 | 139,481 | 161,386 | Mar 03, 2011, 07:05 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Mar 01, 2011 | Sale | $15.02 | 13,750 | 206,512 | 155,136 | Mar 03, 2011, 07:05 PM |
| GAVIN JAMES R III | Director | Jan 18, 2011 | Sale | $14.94 | 671 | 10,025 | 1,580 | Feb 15, 2011, 05:30 PM |
| GAVIN JAMES R III | Director | Jan 18, 2011 | Option Exercise | $14.94 | 2,251 | 33,630 | 2,251 | Feb 15, 2011, 05:30 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Feb 01, 2011 | Option Exercise | $11.13 | 2,500 | 27,813 | 154,139 | Feb 01, 2011, 06:38 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Feb 01, 2011 | Sale | $16.16 | 2,500 | 40,409 | 151,639 | Feb 01, 2011, 06:38 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Jan 18, 2011 | Option Exercise | $11.13 | 2,500 | 27,813 | 154,139 | Jan 18, 2011, 06:38 PM |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | Jan 18, 2011 | Sale | $15.00 | 2,500 | 37,500 | 151,639 | Jan 18, 2011, 06:38 PM |
| BRADBURY DANIEL | President & Chief Executive Of | Nov 22, 2010 | Option Exercise | $11.13 | 25,000 | 278,125 | 74,573 | Nov 22, 2010, 06:29 PM |
| Weyer Christian | SVP, Research & Development | Nov 19, 2010 | Sale | $13.42 | 1,314 | 17,634 | 3,357 | Nov 19, 2010, 08:06 PM |
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Option Exercise
| Owner | Relationship | Date | Value($) |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | 08/08/2012 | 247,194 |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | 08/08/2012 | 113,615 |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | 08/08/2012 | 1,098,206 |
| FOLETTA MARK G | SVP, Chief Financial Officer | 08/08/2012 | 4,011,524 |
| FOLETTA MARK G | SVP, Chief Financial Officer | 08/08/2012 | 3,410 |
| FOLETTA MARK G | SVP, Chief Financial Officer | 08/08/2012 | 247,194 |
| FOLETTA MARK G | SVP, Chief Financial Officer | 08/08/2012 | 119,908 |
| FOLETTA MARK G | SVP, Chief Financial Officer | 08/08/2012 | 2,274,470 |
| BRADBURY DANIEL | President & Chief Executive Of | 08/08/2012 | 13,362,612 |
| BRADBURY DANIEL | President & Chief Executive Of | 08/08/2012 | 741,613 |
| BRADBURY DANIEL | President & Chief Executive Of | 08/08/2012 | 1,144,861 |
| BRADBURY DANIEL | President & Chief Executive Of | 08/08/2012 | 247,194 |
| BRADBURY DANIEL | President & Chief Executive Of | 08/08/2012 | 417,136 |
| BRADBURY DANIEL | President & Chief Executive Of | 08/08/2012 | 1,329,807 |
| BRADBURY DANIEL | President & Chief Executive Of | 08/08/2012 | 3,036,295 |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | 08/08/2012 | 247,194 |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | 08/08/2012 | 64,697 |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | 08/08/2012 | 1,936,539 |
| LEONHARDT HARRY J | SVP, Legal, Compl & Corp Secty | 08/08/2012 | 228,966 |
| LEONHARDT HARRY J | SVP, Legal, Compl & Corp Secty | 08/08/2012 | 22,537 |
| LEONHARDT HARRY J | SVP, Legal, Compl & Corp Secty | 08/08/2012 | 1,199,886 |
| Marshall Paul | SVP, Operations | 08/08/2012 | 65,255 |
| Marshall Paul | SVP, Operations | 08/08/2012 | 983,413 |
| Marshall Paul | SVP, Operations | 08/08/2012 | 247,194 |
| Mihalik Vincent P | SVP, Chief Commercial Officer | 08/08/2012 | 140,089 |
| Mihalik Vincent P | SVP, Chief Commercial Officer | 08/08/2012 | 41,478 |
| Mihalik Vincent P | SVP, Chief Commercial Officer | 08/08/2012 | 1,237,427 |
| Weyer Christian | SVP, Research & Development | 08/08/2012 | 11,129 |
| Weyer Christian | SVP, Research & Development | 08/08/2012 | 41,509 |
| Weyer Christian | SVP, Research & Development | 08/08/2012 | 1,060,417 |
| Weyer Christian | SVP, Research & Development | 08/08/2012 | 247,194 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 08/08/2012 | 4,423,638 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 08/08/2012 | 395,777 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 08/08/2012 | 5,969,391 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 08/08/2012 | 247,194 |
| Gergen Mark J | SVP, Corporate Development | 08/08/2012 | 3,297,222 |
| Gergen Mark J | SVP, Corporate Development | 08/08/2012 | 2,007,250 |
| Gergen Mark J | SVP, Corporate Development | 08/08/2012 | 247,194 |
| Gergen Mark J | SVP, Corporate Development | 08/08/2012 | 80,879 |
| BECK TERESA | Director | 08/08/2012 | 248,000 |
| ADAMS ADRIAN | Director | 08/08/2012 | 651,000 |
| EASTHAM KARIN | Director | 08/08/2012 | 186,000 |
| GAVIN JAMES R III | Director | 08/08/2012 | 141,980 |
| SULLIVAN JOSEPH P | Director | 08/08/2012 | 186,000 |
| SKYLER JAY S | Director | 08/08/2012 | 6,231 |
| SKYLER JAY S | Director | 08/08/2012 | 713,000 |
| SKYLER JAY S | Director | 08/08/2012 | 3,046,866 |
| SKYLER JAY S | Director | 08/08/2012 | 620,000 |
| SKYLER JAY S | Director | 08/08/2012 | 206,925 |
| DENNER ALEXANDER J | Director | 08/08/2012 | 314,991 |
| Costa Paulo F | Director | 08/08/2012 | 806,000 |
| BEHRENS M KATHLEEN | Director | 08/08/2012 | 186,000 |
| Weyer Christian | SVP, Research & Development | 07/25/2012 | 570 |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | 07/25/2012 | 12,032 |
| Mihalik Vincent P | SVP, Chief Commercial Officer | 07/25/2012 | 13,012 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 07/25/2012 | 20,117 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 07/26/2012 | 412,407 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 07/26/2012 | 242,585 |
| Gergen Mark J | SVP, Corporate Development | 07/25/2012 | 13,684 |
| FOLETTA MARK G | SVP, Chief Financial Officer | 07/25/2012 | 12,866 |
| BRADBURY DANIEL | President & Chief Executive Of | 07/26/2012 | 746,840 |
| BRADBURY DANIEL | President & Chief Executive Of | 07/26/2012 | 430,200 |
| SKYLER JAY S | Director | 05/11/2012 | 167,280 |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | 03/28/2012 | 45,100 |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | 03/29/2012 | 75,000 |
| ROWLAND LLOYD A | VP, Chief Compliance Officer | 03/28/2012 | 114,150 |
| Weyer Christian | SVP, Research & Development | 03/01/2012 | 21,062 |
| Mihalik Vincent P | SVP, Chief Commercial Officer | 03/01/2012 | 21,062 |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | 03/01/2012 | 31,585 |
| LEONHARDT HARRY J | SVP, Legal, Compliance and Cor | 03/01/2012 | 21,062 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 03/01/2012 | 31,585 |
| Gergen Mark J | SVP, Corporate Development | 03/01/2012 | 31,585 |
| FOLETTA MARK G | SVP, Chief Financial Officer | 03/01/2012 | 31,585 |
| BRADBURY DANIEL | President & Chief Executive Of | 03/01/2012 | 26,332 |
| Weyer Christian | SVP, Research & Development | 02/23/2012 | 42,899 |
| Mihalik Vincent P | SVP, Chief Commercial Officer | 02/23/2012 | 128,033 |
| Marshall Paul | SVP, Operations | 02/23/2012 | 96,016 |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | 02/23/2012 | 128,033 |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | 02/08/2012 | 93,927 |
| LEONHARDT HARRY J | SVP, Legal, Compliance and Cor | 02/23/2012 | 37,126 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 02/23/2012 | 96,016 |
| Gergen Mark J | SVP, Corporate Development | 02/23/2012 | 128,033 |
| FOLETTA MARK G | SVP, Chief Financial Officer | 02/23/2012 | 96,016 |
| Weyer Christian | SVP, Research & Development | 02/08/2012 | 63,853 |
| Lloyd Marcea Bland | SVP, Chief Administrative Offi | 02/01/2012 | 7,346 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 02/08/2012 | 93,661 |
| LEONHARDT HARRY J | SVP, Legal, Compliance and Cor | 02/08/2012 | 33,615 |
| Gergen Mark J | SVP, Corporate Development | 02/08/2012 | 51,601 |
| FOLETTA MARK G | SVP, Chief Financial Officer | 02/08/2012 | 51,419 |
| Marshall Paul | SVP, Operations | 02/08/2012 | 51,699 |
| Mihalik Vincent P | SVP, Chief Commercial Officer | 02/08/2012 | 63,838 |
| BRADBURY DANIEL | President & Chief Executive Of | 01/18/2012 | 52,005 |
| BRADBURY DANIEL | President & Chief Executive Of | 01/18/2012 | 52,005 |
| DENNER ALEXANDER J | Director | 01/17/2012 | 21,233 |
| BRADBURY DANIEL | President & Chief Executive Of | 10/04/2011 | 253,566 |
| BRADBURY DANIEL | President & Chief Executive Of | 10/04/2011 | 257,850 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 10/04/2011 | 14,315 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 10/03/2011 | 85,950 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 10/04/2011 | 14,325 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 10/03/2011 | 131,224 |
| Costa Paulo F | Director | 08/19/2011 | 98,984 |
| Costa Paulo F | Director | 08/17/2011 | 107,083 |
| ADAMS ADRIAN | Director | 08/15/2011 | 161,095 |
| SKYLER JAY S | Director | 05/24/2011 | 33,082 |
| SKYLER JAY S | Director | 05/24/2011 | 33,090 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 03/01/2011 | 139,481 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 03/01/2011 | 206,512 |
| GAVIN JAMES R III | Director | 01/18/2011 | 10,025 |
| GAVIN JAMES R III | Director | 01/18/2011 | 33,630 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 02/01/2011 | 27,813 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 02/01/2011 | 40,409 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 01/18/2011 | 27,813 |
| KOLTERMAN ORVILLE G | SVP, Chief Medical Officer | 01/18/2011 | 37,500 |
| BRADBURY DANIEL | President & Chief Executive Of | 11/22/2010 | 278,125 |
| Weyer Christian | SVP, Research & Development | 11/19/2010 | 17,634 |
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