. (AEGR)
$1.97 - (-)
Market Cap: -
As of 01/13/17 12:00 AM EST. Market closed.
. (AEGR)
$1.97
- (-)
Market Cap: -
As of 01/13/17 12:00 AM EST. Market closed.
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Previous Close
$1.97
Days Range
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52 week range
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Volume
0
Avg. Volume (30 days)
0
Market Cap
-
Dividend Yield
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Open
-
Previous Close
$1.97
Days Range
- - -
52 week range
- - -
Volume
0
Avg. Volume (30 days)
0
Market Cap
-
Dividend Yield
-
P/E
-
Shares Outstanding
0
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INSIDER TRANSACTIONS FOR
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| Harshbarger Benjamin | General Counsel | Sep 17, 2016 | Option Exercise | $1.78 | 532 | 947 | 1,704 | Sep 20, 2016, 04:03 PM |
| Harshbarger Benjamin | General Counsel | Apr 01, 2016 | Option Exercise | $3.55 | 273 | 969 | 594 | Sep 20, 2016, 04:03 PM |
| Broadfin Healthcare Master Fund Ltd | 10% Owner | Sep 13, 2016 | Buy | $1.75 | 75,000 | 131,250 | 4,361,291 | Sep 14, 2016, 04:16 PM |
| Broadfin Healthcare Master Fund Ltd | 10% Owner | Sep 12, 2016 | Buy | $1.70 | 176,000 | 298,800 | 4,286,291 | Sep 12, 2016, 06:44 PM |
| Broadfin Healthcare Master Fund Ltd | 10% Owner | Sep 09, 2016 | Buy | $1.60 | 100,000 | 159,500 | 4,110,291 | Sep 12, 2016, 06:44 PM |
| SMITH SANDFORD D | Director | Jul 27, 2016 | Option Exercise | $1.55 | 777 | 1,204 | 2,890 | Jul 29, 2016, 04:01 PM |
| Broadfin Healthcare Master Fund Ltd | 10% Owner | Mar 18, 2016 | Option Exercise | $7.50 | 497,600 | 3,732,000 | 4,010,291 | Mar 21, 2016, 04:48 PM |
| Broadfin Healthcare Master Fund Ltd | 10% Owner | Mar 17, 2016 | Option Exercise | $7.50 | 2,400 | 18,000 | 3,512,691 | Mar 21, 2016, 04:48 PM |
| SMITH SANDFORD D | Director | Jan 27, 2016 | Option Exercise | $6.78 | 778 | 5,275 | 1,445 | Jan 29, 2016, 06:05 AM |
| Broadfin Healthcare Master Fund Ltd | 10% Owner | Nov 11, 2015 | Buy | $10.96 | 40,100 | 439,649 | 4,010,291 | Nov 13, 2015, 03:24 PM |
| Fitzpatrick Mark J. | Chief Financial Officer | Aug 19, 2014 | Buy | $30.64 | 1,150 | 35,236 | 9,500 | Aug 20, 2014, 09:36 AM |
| Beer Marc D | Chief Executive Officer | Jul 31, 2014 | Buy | $33.65 | 10,000 | 336,539 | 79,400 | Jul 31, 2014, 12:30 PM |
| Beer Marc D | Chief Executive Officer | Jun 03, 2014 | Buy | $30.12 | 10,000 | 301,200 | 69,400 | Jun 04, 2014, 09:30 AM |
| Beer Marc D | Chief Executive Officer | May 27, 2014 | Buy | $31.59 | 10,000 | 315,900 | 59,400 | May 27, 2014, 12:57 PM |
| Beer Marc D | Chief Executive Officer | May 21, 2014 | Option Exercise | $1.54 | 6,400 | 9,856 | 49,400 | May 22, 2014, 09:39 AM |
| Beer Marc D | Chief Executive Officer | May 20, 2014 | Buy | $30.53 | 10,000 | 305,300 | 43,000 | May 21, 2014, 09:40 AM |
| VANLENT ANNE | Director | May 08, 2014 | Buy | $33.78 | 4,000 | 135,110 | 4,000 | May 09, 2014, 09:24 AM |
| Beer Marc D | Chief Executive Officer | May 08, 2014 | Buy | $35.31 | 30,000 | 1,059,300 | 33,000 | May 08, 2014, 10:20 AM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Mar 31, 2014 | Option Exercise | $13.01 | 2,250 | 29,273 | 2,250 | Apr 02, 2014, 04:01 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Mar 31, 2014 | Sale | $46.20 | 2,250 | 103,947 | 1,101 | Apr 02, 2014, 04:01 PM |
| Beer Marc D | Chief Executive Officer | Mar 26, 2014 | Option Exercise | $1.54 | 3,000 | 4,620 | 3,000 | Mar 27, 2014, 05:26 PM |
| Sumeray Mark | Chief Medical Officer | Mar 14, 2014 | Option Exercise | $13.01 | 2,000 | 26,020 | 2,000 | Mar 18, 2014, 04:01 PM |
| Sumeray Mark | Chief Medical Officer | Mar 14, 2014 | Sale | $51.34 | 2,000 | 102,670 | 1,700 | Mar 18, 2014, 04:01 PM |
| Fitzpatrick Mark J. | Chief Financial Officer | Mar 04, 2014 | Option Exercise | $17.64 | 2,500 | 44,100 | 8,350 | Mar 05, 2014, 06:46 PM |
| Sumeray Mark | Chief Medical Officer | Feb 14, 2014 | Option Exercise | $13.01 | 2,000 | 26,020 | 2,000 | Feb 18, 2014, 04:05 PM |
| Sumeray Mark | Chief Medical Officer | Feb 14, 2014 | Sale | $63.48 | 2,000 | 126,970 | 500 | Feb 18, 2014, 04:05 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Feb 11, 2014 | Option Exercise | $13.01 | 2,250 | 29,273 | 2,250 | Feb 12, 2014, 04:01 PM |
| Fitzpatrick Mark J. | Chief Financial Officer | Feb 10, 2014 | Option Exercise | $17.64 | 7,500 | 132,300 | 13,350 | Feb 12, 2014, 04:01 PM |
| Fitzpatrick Mark J. | Chief Financial Officer | Feb 10, 2014 | Sale | $62.61 | 7,500 | 469,543 | 10,050 | Feb 12, 2014, 04:01 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Feb 11, 2014 | Sale | $67.00 | 2,250 | 150,750 | 0 | Feb 12, 2014, 04:01 PM |
| Sumeray Mark | Chief Medical Officer | Jan 16, 2014 | Option Exercise | $13.01 | 2,000 | 26,020 | 2,000 | Jan 21, 2014, 04:01 PM |
| Sumeray Mark | Chief Medical Officer | Jan 16, 2014 | Sale | $58.63 | 2,000 | 117,269 | 100 | Jan 21, 2014, 04:01 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Jan 02, 2014 | Option Exercise | $13.01 | 2,250 | 29,273 | 2,250 | Jan 06, 2014, 04:02 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Jan 02, 2014 | Sale | $71.11 | 2,250 | 159,998 | 1,350 | Jan 06, 2014, 04:02 PM |
| Sumeray Mark | Chief Medical Officer | Jan 02, 2014 | Option Exercise | $13.01 | 1,000 | 13,010 | 1,000 | Jan 06, 2014, 04:01 PM |
| Sumeray Mark | Chief Medical Officer | Jan 02, 2014 | Sale | $70.93 | 1,000 | 70,934 | 600 | Jan 06, 2014, 04:01 PM |
| Sumeray Mark | Chief Medical Officer | Dec 16, 2013 | Option Exercise | $13.01 | 2,000 | 26,020 | 2,000 | Dec 17, 2013, 04:06 PM |
| Sumeray Mark | Chief Medical Officer | Dec 16, 2013 | Sale | $66.34 | 2,000 | 132,687 | 200 | Dec 17, 2013, 04:06 PM |
| Beer Marc D | Chief Executive Officer | Dec 04, 2013 | Option Exercise | $1.54 | 4,380 | 6,745 | 4,380 | Dec 06, 2013, 07:24 AM |
| Sumeray Mark | Chief Medical Officer | Dec 02, 2013 | Option Exercise | $13.01 | 3,000 | 39,030 | 3,000 | Dec 04, 2013, 05:01 PM |
| Sumeray Mark | Chief Medical Officer | Dec 02, 2013 | Sale | $70.42 | 3,000 | 211,267 | 600 | Dec 04, 2013, 05:01 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Dec 02, 2013 | Option Exercise | $13.01 | 2,250 | 29,273 | 2,250 | Dec 04, 2013, 05:00 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Dec 02, 2013 | Sale | $70.41 | 2,250 | 158,423 | 700 | Dec 04, 2013, 05:00 PM |
| Sumeray Mark | Chief Medical Officer | Nov 15, 2013 | Option Exercise | $13.01 | 2,000 | 26,020 | 2,000 | Nov 19, 2013, 05:00 PM |
| Sumeray Mark | Chief Medical Officer | Nov 15, 2013 | Sale | $76.09 | 2,000 | 152,182 | 1,511 | Nov 19, 2013, 05:00 PM |
| Fitzpatrick Mark J. | Chief Financial Officer | Nov 11, 2013 | Option Exercise | $17.64 | 10,350 | 182,574 | 10,500 | Nov 13, 2013, 05:31 PM |
| Fitzpatrick Mark J. | Chief Financial Officer | Nov 11, 2013 | Sale | $79.04 | 7,500 | 592,829 | 10,300 | Nov 13, 2013, 05:31 PM |
| Beer Marc D | Chief Executive Officer | Nov 05, 2013 | Option Exercise | $1.54 | 39,000 | 60,060 | 234,726 | Nov 06, 2013, 05:05 PM |
| Carter Martha J. | Chief Regulatory Officer & SVP | Nov 01, 2013 | Option Exercise | $14.84 | 5,000 | 74,200 | 6,500 | Nov 05, 2013, 04:01 PM |
| Carter Martha J. | Chief Regulatory Officer & SVP | Nov 01, 2013 | Sale | $82.81 | 5,000 | 414,050 | 1,500 | Nov 05, 2013, 04:01 PM |
| Sumeray Mark | Chief Medical Officer | Nov 01, 2013 | Option Exercise | $13.01 | 3,500 | 45,535 | 3,500 | Nov 05, 2013, 04:00 PM |
| Sumeray Mark | Chief Medical Officer | Nov 01, 2013 | Sale | $83.28 | 3,500 | 291,481 | 2,100 | Nov 05, 2013, 04:00 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Nov 01, 2013 | Option Exercise | $13.01 | 2,250 | 29,273 | 2,250 | Nov 05, 2013, 04:00 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Nov 01, 2013 | Sale | $83.23 | 2,250 | 187,275 | 1,950 | Nov 05, 2013, 04:00 PM |
| Beer Marc D | Chief Executive Officer | Oct 30, 2013 | Option Exercise | $1.54 | 40,000 | 61,600 | 235,726 | Oct 31, 2013, 08:35 AM |
| Beer Marc D | Chief Executive Officer | Oct 30, 2013 | Sale | $87.79 | 40,000 | 3,511,665 | 232,926 | Oct 31, 2013, 08:35 AM |
| SMITH SANDFORD D | Director | Oct 29, 2013 | Option Exercise | $15.00 | 2,502 | 37,530 | 2,502 | Oct 31, 2013, 08:32 AM |
| SMITH SANDFORD D | Director | Oct 29, 2013 | Sale | $95.00 | 2,502 | 237,690 | 0 | Oct 31, 2013, 08:32 AM |
| Sumeray Mark | Chief Medical Officer | Oct 15, 2013 | Option Exercise | $13.01 | 2,000 | 26,020 | 2,000 | Oct 16, 2013, 05:04 PM |
| Sumeray Mark | Chief Medical Officer | Oct 15, 2013 | Sale | $80.33 | 2,000 | 160,659 | 1,000 | Oct 16, 2013, 05:04 PM |
| Sumeray Mark | Chief Medical Officer | Oct 07, 2013 | Option Exercise | $13.01 | 3,500 | 45,535 | 3,500 | Oct 08, 2013, 05:15 PM |
| Sumeray Mark | Chief Medical Officer | Oct 07, 2013 | Sale | $93.17 | 3,500 | 326,086 | 1,965 | Oct 08, 2013, 05:15 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Oct 07, 2013 | Option Exercise | $13.01 | 20,000 | 260,200 | 20,000 | Oct 08, 2013, 04:58 PM |
| Fraser Craig | Pres., US/Int. Comm. & Manuf. | Oct 07, 2013 | Sale | $93.16 | 20,000 | 1,863,146 | 10,992 | Oct 08, 2013, 04:58 PM |
| Sumeray Mark | Chief Medical Officer | Sep 16, 2013 | Option Exercise | $13.01 | 2,000 | 26,020 | 2,000 | Sep 18, 2013, 04:05 PM |
| Sumeray Mark | Chief Medical Officer | Sep 16, 2013 | Sale | $89.77 | 2,000 | 179,549 | 1,400 | Sep 18, 2013, 04:05 PM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Sep 05, 2013 | Sale | $89.20 | 750,000 | 66,899,998 | 2,873,426 | Sep 09, 2013, 06:15 PM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Jun 15, 2013 | Option Exercise | $25.00 | 200,000 | 5,000,000 | 3,573,426 | Sep 09, 2013, 06:15 PM |
| Fitzpatrick Mark J. | Chief Financial Officer | Aug 26, 2013 | Option Exercise | $17.64 | 2,500 | 44,100 | 3,000 | Aug 28, 2013, 04:30 PM |
| Scheer David | Director | Aug 21, 2013 | Sale | $84.58 | 20,000 | 1,691,638 | 620,554 | Aug 23, 2013, 08:00 AM |
| Sumeray Mark | Chief Medical Officer | Aug 16, 2013 | Option Exercise | $13.01 | 2,000 | 26,020 | 2,000 | Aug 20, 2013, 05:06 PM |
| Sumeray Mark | Chief Medical Officer | Aug 16, 2013 | Sale | $88.71 | 2,000 | 177,413 | 1,100 | Aug 20, 2013, 05:06 PM |
| Fitzpatrick Mark J. | Chief Financial Officer | Aug 14, 2013 | Option Exercise | $17.64 | 7,500 | 132,300 | 8,000 | Aug 16, 2013, 04:56 PM |
| Fitzpatrick Mark J. | Chief Financial Officer | Aug 14, 2013 | Sale | $93.44 | 7,500 | 700,816 | 5,488 | Aug 16, 2013, 04:56 PM |
| Beer Marc D | Chief Executive Officer | Aug 15, 2013 | Option Exercise | $1.54 | 60,000 | 92,400 | 259,061 | Aug 16, 2013, 04:56 PM |
| Beer Marc D | Chief Executive Officer | Aug 15, 2013 | Sale | $88.54 | 60,000 | 5,312,209 | 238,897 | Aug 16, 2013, 04:56 PM |
| SMITH SANDFORD D | Director | Aug 09, 2013 | Option Exercise | $16.05 | 10,000 | 160,518 | 10,000 | Aug 13, 2013, 04:00 PM |
| SMITH SANDFORD D | Director | Aug 12, 2013 | Sale | $92.25 | 1,537 | 141,791 | 0 | Aug 13, 2013, 04:00 PM |
| SMITH SANDFORD D | Director | Aug 09, 2013 | Sale | $92.33 | 8,463 | 781,414 | 1,537 | Aug 13, 2013, 04:00 PM |
| Sumeray Mark | Chief Medical Officer | Jul 15, 2013 | Option Exercise | $13.01 | 2,000 | 26,020 | 2,000 | Jul 16, 2013, 05:00 PM |
| Sumeray Mark | Chief Medical Officer | Jul 15, 2013 | Sale | $78.77 | 2,000 | 157,546 | 1,500 | Jul 16, 2013, 05:00 PM |
| Sumeray Mark | Chief Medical Officer | Jun 17, 2013 | Option Exercise | $13.01 | 6,000 | 78,060 | 6,000 | Jun 19, 2013, 04:00 PM |
| Sumeray Mark | Chief Medical Officer | Jun 17, 2013 | Sale | $65.27 | 6,000 | 391,620 | 4,191 | Jun 19, 2013, 04:00 PM |
| Sumeray Mark | Chief Medical Officer | May 15, 2013 | Option Exercise | $13.01 | 6,000 | 78,060 | 6,000 | May 17, 2013, 04:30 PM |
| Sumeray Mark | Chief Medical Officer | May 15, 2013 | Sale | $47.32 | 6,000 | 283,930 | 0 | May 17, 2013, 04:30 PM |
| Sumeray Mark | Chief Medical Officer | Apr 22, 2013 | Option Exercise | $13.01 | 6,000 | 78,060 | 6,000 | Apr 24, 2013, 02:23 PM |
| Sumeray Mark | Chief Medical Officer | Apr 22, 2013 | Sale | $40.74 | 6,000 | 244,451 | 2,150 | Apr 24, 2013, 02:23 PM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Feb 01, 2013 | Buy | $27.79 | 50,000 | 1,389,400 | 3,373,426 | Feb 05, 2013, 03:54 PM |
| Carter Martha J. | Chief Regulatory Officer & SVP | Jan 23, 2013 | Buy | $27.81 | 500 | 13,905 | 1,500 | Jan 24, 2013, 05:12 PM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Jan 18, 2013 | Buy | $27.62 | 50,000 | 1,381,000 | 3,323,426 | Jan 22, 2013, 01:16 PM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Jan 17, 2013 | Buy | $26.73 | 50,000 | 1,336,285 | 3,273,426 | Jan 18, 2013, 01:57 PM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Jan 11, 2013 | Buy | $27.07 | 475,000 | 12,857,220 | 3,223,426 | Jan 15, 2013, 06:07 PM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Dec 04, 2012 | Buy | $21.27 | 20,000 | 425,400 | 2,615,293 | Dec 05, 2012, 01:05 PM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Nov 29, 2012 | Buy | $22.71 | 30,000 | 681,300 | 2,595,293 | Dec 03, 2012, 02:29 PM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Nov 20, 2012 | Buy | $21.01 | 20,000 | 420,200 | 2,475,293 | Dec 03, 2012, 10:36 AM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Nov 15, 2012 | Buy | $19.50 | 10,000 | 195,000 | 2,455,293 | Dec 03, 2012, 10:36 AM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Nov 07, 2012 | Buy | $21.12 | 30,000 | 633,600 | 2,445,293 | Dec 03, 2012, 10:36 AM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Nov 28, 2012 | Buy | $21.76 | 70,000 | 1,523,200 | 2,565,293 | Dec 03, 2012, 10:36 AM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Nov 21, 2012 | Buy | $20.75 | 20,000 | 415,000 | 2,495,293 | Dec 03, 2012, 10:36 AM |
| PERCEPTIVE ADVISORS LLC | 10% Owner | Oct 19, 2012 | Option Exercise | $17.50 | 247,500 | 4,331,250 | 2,347,233 | Dec 03, 2012, 10:34 AM |
| ALTA BIOPHARMA PARTNERS III LP | 10% Owner | Oct 16, 2012 | Sale | $18.67 | 128,229 | 2,394,035 | 2,280,197 | Oct 17, 2012, 06:35 PM |
| ALTA BIOPHARMA PARTNERS III LP | 10% Owner | Oct 15, 2012 | Sale | $17.54 | 55,626 | 975,680 | 2,408,426 | Oct 17, 2012, 06:35 PM |
| ALTA BIOPHARMA PARTNERS III LP | 10% Owner | Oct 16, 2012 | Sale | $18.67 | 11,771 | 219,765 | 153,131 | Oct 17, 2012, 06:35 PM |
| ALTA BIOPHARMA PARTNERS III LP | 10% Owner | Oct 15, 2012 | Sale | $17.54 | 5,107 | 89,577 | 161,742 | Oct 17, 2012, 06:35 PM |
| Carter Martha J. | Chief Regulatory Officer | Mar 30, 2012 | Buy | $14.03 | 1,000 | 14,030 | 1,000 | Apr 02, 2012, 01:10 PM |
| Beer Marc D | Chief Executive Officer | Mar 29, 2012 | Buy | $13.74 | 1,000 | 13,735 | 199,061 | Mar 30, 2012, 09:19 AM |
| Fitzpatrick Mark J. | Chief Financial Officer | Mar 23, 2012 | Buy | $14.15 | 500 | 7,076 | 500 | Mar 26, 2012, 09:27 AM |
| Beer Marc D | Chief Executive Officer | Mar 22, 2012 | Buy | $13.96 | 1,000 | 13,964 | 198,061 | Mar 23, 2012, 10:02 AM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Mar 09, 2012 | Sale | $15.87 | 100,000 | 1,586,830 | 2,457,879 | Mar 14, 2012, 03:29 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Mar 09, 2012 | Sale | $15.87 | 98,897 | 1,569,327 | 2,430,765 | Mar 14, 2012, 03:19 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Mar 09, 2012 | Sale | $15.87 | 40,077 | 635,954 | 985,052 | Mar 14, 2012, 03:16 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Mar 09, 2012 | Sale | $15.87 | 58,820 | 933,373 | 1,445,713 | Mar 14, 2012, 03:09 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Mar 09, 2012 | Sale | $15.87 | 98,897 | 1,569,327 | 2,430,765 | Mar 14, 2012, 03:08 PM |
| Advent Partners HLS III Limited Partnership | Member of Group > 10% | Mar 09, 2012 | Sale | $15.87 | 1,103 | 17,503 | 27,114 | Mar 14, 2012, 03:04 PM |
| Index Venture Associates III Ltd | 10% Owner | Jan 30, 2012 | Sale | $17.08 | 50,000 | 854,000 | 2,081,827 | Feb 01, 2012, 08:18 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Jan 31, 2012 | Sale | $17.10 | 22,054 | 377,156 | 2,529,662 | Jan 31, 2012, 06:02 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Jan 30, 2012 | Sale | $17.06 | 2,670 | 45,563 | 2,551,716 | Jan 31, 2012, 06:02 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Jan 27, 2012 | Sale | $17.17 | 49,448 | 848,800 | 2,554,386 | Jan 31, 2012, 06:02 PM |
| Advent Partners HLS III Limited Partnership | Member of Group > 10% | Jan 31, 2012 | Sale | $17.10 | 246 | 4,207 | 28,217 | Jan 31, 2012, 06:01 PM |
| Advent Partners HLS III Limited Partnership | Member of Group > 10% | Jan 30, 2012 | Sale | $17.06 | 30 | 512 | 28,463 | Jan 31, 2012, 06:01 PM |
| Advent Partners HLS III Limited Partnership | Member of Group > 10% | Jan 27, 2012 | Sale | $17.17 | 552 | 9,475 | 28,493 | Jan 31, 2012, 06:01 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Jan 31, 2012 | Sale | $17.10 | 22,054 | 377,156 | 2,529,662 | Jan 31, 2012, 06:00 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Jan 30, 2012 | Sale | $17.06 | 2,670 | 45,563 | 2,551,716 | Jan 31, 2012, 06:00 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Jan 27, 2012 | Sale | $17.17 | 49,448 | 848,800 | 2,554,386 | Jan 31, 2012, 06:00 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Jan 31, 2012 | Sale | $17.10 | 22,300 | 381,363 | 2,557,879 | Jan 31, 2012, 05:59 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Jan 30, 2012 | Sale | $17.06 | 2,700 | 46,075 | 2,580,179 | Jan 31, 2012, 05:59 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Jan 27, 2012 | Sale | $17.17 | 50,000 | 858,275 | 2,582,879 | Jan 31, 2012, 05:59 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Jan 30, 2012 | Sale | $17.06 | 1,588 | 27,099 | 1,517,650 | Jan 31, 2012, 05:55 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Jan 27, 2012 | Sale | $17.17 | 29,409 | 504,820 | 1,519,238 | Jan 31, 2012, 05:55 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Jan 31, 2012 | Sale | $17.10 | 13,117 | 224,320 | 1,504,533 | Jan 31, 2012, 05:55 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Jan 31, 2012 | Sale | $17.10 | 8,937 | 152,836 | 1,025,129 | Jan 31, 2012, 05:53 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Jan 30, 2012 | Sale | $17.06 | 1,082 | 18,464 | 1,034,066 | Jan 31, 2012, 05:53 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Jan 27, 2012 | Sale | $17.17 | 20,039 | 343,979 | 1,035,148 | Jan 31, 2012, 05:53 PM |
| Advent Partners HLS III Limited Partnership | Member of Group > 10% | Dec 08, 2011 | Sale | $16.90 | 28 | 473 | 29,241 | Dec 09, 2011, 05:32 PM |
| Advent Partners HLS III Limited Partnership | Member of Group > 10% | Dec 09, 2011 | Sale | $16.89 | 196 | 3,311 | 29,045 | Dec 09, 2011, 05:32 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Dec 09, 2011 | Sale | $16.89 | 10,448 | 176,473 | 1,548,647 | Dec 09, 2011, 05:31 PM | |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Dec 08, 2011 | Sale | $16.90 | 1,470 | 24,836 | 1,559,095 | Dec 09, 2011, 05:31 PM | |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Dec 09, 2011 | Sale | $16.89 | 7,119 | 120,244 | 1,055,187 | Dec 09, 2011, 05:30 PM | |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Dec 08, 2011 | Sale | $16.90 | 1,002 | 16,929 | 1,062,306 | Dec 09, 2011, 05:30 PM | |
| AHLS III GP LIMITED PARTNERSHIP | Dec 09, 2011 | Sale | $16.89 | 17,567 | 296,717 | 2,603,834 | Dec 09, 2011, 05:30 PM | |
| AHLS III GP LIMITED PARTNERSHIP | Dec 08, 2011 | Sale | $16.90 | 2,472 | 41,765 | 2,621,401 | Dec 09, 2011, 05:30 PM | |
| ADVENT INTERNATIONAL LLC | Dec 09, 2011 | Sale | $16.89 | 17,567 | 296,717 | 2,603,834 | Dec 09, 2011, 05:29 PM | |
| ADVENT INTERNATIONAL LLC | Dec 08, 2011 | Sale | $16.90 | 2,472 | 41,765 | 2,621,401 | Dec 09, 2011, 05:29 PM | |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Dec 09, 2011 | Sale | $16.89 | 17,763 | 300,028 | 2,632,879 | Dec 09, 2011, 05:28 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Dec 08, 2011 | Sale | $16.90 | 2,500 | 42,238 | 2,650,642 | Dec 09, 2011, 05:28 PM |
| Advent Partners HLS III Limited Partnership | Member of Group > 10% | Dec 06, 2011 | Sale | $16.96 | 61 | 1,034 | 29,269 | Dec 08, 2011, 05:06 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Dec 06, 2011 | Sale | $16.96 | 3,274 | 55,520 | 1,560,565 | Dec 08, 2011, 05:06 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Dec 06, 2011 | Sale | $16.96 | 2,230 | 37,816 | 1,063,308 | Dec 08, 2011, 05:05 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Dec 06, 2011 | Sale | $16.96 | 5,504 | 93,337 | 2,623,873 | Dec 08, 2011, 05:03 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Dec 06, 2011 | Sale | $16.96 | 5,504 | 93,337 | 2,623,873 | Dec 08, 2011, 05:02 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Dec 06, 2011 | Sale | $16.96 | 5,565 | 94,371 | 2,653,142 | Dec 08, 2011, 05:01 PM |
| Beer Marc D | Chief Executive Officer | Sep 01, 2011 | Buy | $14.76 | 1,484 | 21,904 | 7,156 | Sep 06, 2011, 01:59 PM |
| Beer Marc D | Chief Executive Officer | Sep 01, 2011 | Buy | $14.75 | 5,270 | 77,733 | 197,061 | Sep 06, 2011, 01:59 PM |
| Beer Marc D | Chief Executive Officer | Aug 09, 2011 | Buy | $11.91 | 1,800 | 21,438 | 133,147 | Aug 10, 2011, 09:42 AM |
| Beer Marc D | Chief Executive Officer | Aug 09, 2011 | Buy | $11.96 | 8,265 | 98,849 | 131,347 | Aug 10, 2011, 09:42 AM |
| Kiley Alison | Director | Aug 08, 2011 | Buy | $12.43 | 4,200 | 52,204 | 2,684,751 | Aug 09, 2011, 05:40 PM |
| Kiley Alison | Director | Aug 09, 2011 | Buy | $12.45 | 5,500 | 68,497 | 2,690,251 | Aug 09, 2011, 05:40 PM |
| ALTA BIOPHARMA PARTNERS III LP | 10% Owner | Aug 09, 2011 | Buy | $12.45 | 5,500 | 68,497 | 2,464,052 | Aug 09, 2011, 05:37 PM |
| ALTA BIOPHARMA PARTNERS III LP | 10% Owner | Aug 08, 2011 | Buy | $12.43 | 4,200 | 52,204 | 2,459,014 | Aug 09, 2011, 05:37 PM |
| Beer Marc D | Chief Executive Officer | Aug 01, 2011 | Buy | $15.74 | 1,392 | 21,910 | 123,082 | Aug 03, 2011, 02:30 PM |
| Beer Marc D | Chief Executive Officer | Aug 01, 2011 | Buy | $15.74 | 4,938 | 77,724 | 121,690 | Aug 03, 2011, 02:30 PM |
| Index Venture Associates III Ltd | 10% Owner | Jul 29, 2011 | Sale | $14.61 | 36,788 | 537,425 | 2,131,827 | Aug 02, 2011, 12:12 PM |
| Ollier Michele | Director | Jul 29, 2011 | Sale | $14.61 | 36,788 | 537,425 | 2,131,827 | Aug 02, 2011, 12:02 PM |
| Advent Partners HLS III Limited Partnership | Member of Group > 10% | Jul 29, 2011 | Sale | $14.61 | 57 | 833 | 29,330 | Jul 29, 2011, 04:40 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Jul 29, 2011 | Sale | $14.61 | 3,015 | 44,045 | 1,563,839 | Jul 29, 2011, 04:39 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Jul 29, 2011 | Sale | $14.61 | 2,054 | 30,006 | 1,065,538 | Jul 29, 2011, 04:38 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Jul 29, 2011 | Sale | $14.61 | 5,069 | 74,051 | 2,629,377 | Jul 29, 2011, 04:38 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Jul 29, 2011 | Sale | $14.61 | 5,069 | 74,051 | 2,629,377 | Jul 29, 2011, 04:36 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Jul 29, 2011 | Sale | $14.61 | 5,126 | 74,884 | 2,658,707 | Jul 29, 2011, 04:35 PM |
| Index Venture Associates III Ltd | 10% Owner | Jun 29, 2011 | Sale | $14.61 | 877,723 | 12,822,392 | 2,168,435 | Jul 01, 2011, 02:38 PM |
| Ollier Michele | Director | Jun 29, 2011 | Sale | $14.61 | 877,723 | 12,822,392 | 2,168,435 | Jul 01, 2011, 02:25 PM |
| Advent Partners HLS III Limited Partnership | Member of Group > 10% | Jun 29, 2011 | Sale | $14.61 | 1,349 | 19,707 | 29,387 | Jun 29, 2011, 04:48 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Jun 29, 2011 | Sale | $14.61 | 71,923 | 1,050,702 | 1,566,854 | Jun 29, 2011, 04:47 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Jun 29, 2011 | Sale | $14.61 | 49,005 | 715,899 | 1,067,592 | Jun 29, 2011, 04:46 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Jun 29, 2011 | Sale | $14.61 | 120,928 | 1,766,601 | 2,634,446 | Jun 29, 2011, 04:44 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Jun 29, 2011 | Sale | $14.61 | 120,928 | 1,766,601 | 2,634,446 | Jun 29, 2011, 04:43 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Jun 29, 2011 | Sale | $14.61 | 122,277 | 1,786,308 | 2,663,833 | Jun 29, 2011, 04:42 PM |
| Beer Marc D | Chief Executive Officer | Jun 29, 2011 | Buy | $15.50 | 64,516 | 999,998 | 181,268 | Jun 29, 2011, 02:54 PM |
| Beer Marc D | Chief Executive Officer | Jun 01, 2011 | Buy | $18.73 | 1,170 | 21,914 | 116,752 | Jun 03, 2011, 09:00 AM |
| Beer Marc D | Chief Executive Officer | Jun 01, 2011 | Buy | $18.69 | 4,162 | 77,788 | 115,582 | Jun 03, 2011, 09:00 AM |
| Beer Marc D | Chief Executive Officer | Apr 04, 2011 | Buy | $16.73 | 4,647 | 77,744 | 110,110 | Apr 05, 2011, 05:00 PM |
| Beer Marc D | Chief Executive Officer | Apr 04, 2011 | Buy | $16.73 | 1,310 | 21,916 | 111,420 | Apr 05, 2011, 05:00 PM |
| Scheer David | Director | Mar 11, 2011 | Buy | $15.36 | 6,006 | 92,252 | 650,154 | Mar 14, 2011, 12:25 PM |
| Scheer David | Director | Mar 10, 2011 | Buy | $15.11 | 3,994 | 60,349 | 644,148 | Mar 14, 2011, 12:25 PM |
| Beer Marc D | Chief Executive Officer | Dec 15, 2010 | Buy | $12.33 | 200 | 2,465 | 105,463 | Dec 17, 2010, 05:27 PM |
| Kiley Alison | Director | Oct 27, 2010 | Buy | $9.50 | 315,789 | 2,999,996 | 2,680,551 | Nov 10, 2010, 03:47 PM |
| ALTA BIOPHARMA PARTNERS III LP | 10% Owner | Oct 27, 2010 | Option Exercise | $7.60 | 764,310 | 5,808,756 | 2,165,931 | Oct 27, 2010, 06:06 PM |
| ALTA BIOPHARMA PARTNERS III LP | 10% Owner | Oct 27, 2010 | Buy | $9.50 | 315,789 | 2,999,996 | 2,455,167 | Oct 27, 2010, 06:06 PM |
| Lewis William | President, PFO and Treasurer | Oct 27, 2010 | Option Exercise | $7.60 | 35,006 | 266,046 | 108,966 | Oct 27, 2010, 05:49 PM |
| Kiley Alison | Director | Oct 27, 2010 | Option Exercise | $7.60 | 764,310 | 5,808,756 | 2,364,762 | Oct 27, 2010, 05:48 PM |
| Kiley Alison | Director | Oct 27, 2010 | Buy | $9.50 | 315,789 | 2,999,996 | 2,860,551 | Oct 27, 2010, 05:48 PM |
| Index Venture Associates III Ltd | 10% Owner | Oct 27, 2010 | Option Exercise | $7.60 | 881,128 | 6,696,573 | 2,726,197 | Oct 27, 2010, 05:46 PM |
| Index Venture Associates III Ltd | 10% Owner | Oct 27, 2010 | Buy | $9.50 | 315,789 | 2,999,996 | 3,041,986 | Oct 27, 2010, 05:46 PM |
| FISHERMAN JASON S | Director | Oct 27, 2010 | Option Exercise | $7.60 | 2,286 | 17,374 | 7,109 | Oct 27, 2010, 05:44 PM |
| FISHERMAN JASON S | Director | Oct 27, 2010 | Option Exercise | $7.60 | 2,286 | 17,374 | 4,823 | Oct 27, 2010, 05:44 PM |
| FISHERMAN JASON S | Director | Oct 27, 2010 | Buy | $9.50 | 739 | 7,021 | 7,848 | Oct 27, 2010, 05:44 PM |
| FISHERMAN JASON S | Director | Oct 27, 2010 | Buy | $9.50 | 739 | 7,021 | 7,109 | Oct 27, 2010, 05:44 PM |
| Beer Marc D | Chief Executive Officer | Oct 27, 2010 | Buy | $9.50 | 105,263 | 999,999 | 105,263 | Oct 27, 2010, 05:43 PM |
| Ollier Michele | Director | Oct 27, 2010 | Option Exercise | $7.60 | 881,128 | 6,696,573 | 2,730,369 | Oct 27, 2010, 05:42 PM |
| Ollier Michele | Director | Oct 27, 2010 | Buy | $9.50 | 315,789 | 2,999,996 | 3,046,158 | Oct 27, 2010, 05:42 PM |
| Advent Partners HLS III Limited Partnership | Oct 27, 2010 | Option Exercise | $7.60 | 8,952 | 68,035 | 27,841 | Oct 27, 2010, 05:40 PM | |
| Advent Partners HLS III Limited Partnership | Oct 27, 2010 | Buy | $9.50 | 2,895 | 27,503 | 30,736 | Oct 27, 2010, 05:40 PM | |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Oct 27, 2010 | Option Exercise | $7.60 | 478,852 | 3,639,275 | 1,005,135 | Oct 27, 2010, 05:39 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Oct 27, 2010 | Option Exercise | $7.60 | 478,852 | 3,639,275 | 1,483,987 | Oct 27, 2010, 05:39 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Oct 27, 2010 | Buy | $9.50 | 154,790 | 1,470,505 | 1,483,987 | Oct 27, 2010, 05:39 PM |
| Advent Healthcare & Life Sciences III-A Limited Partnership | Member of Group > 10% | Oct 27, 2010 | Buy | $9.50 | 154,790 | 1,470,505 | 1,638,777 | Oct 27, 2010, 05:39 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Oct 27, 2010 | Option Exercise | $7.60 | 326,288 | 2,479,789 | 1,011,124 | Oct 27, 2010, 05:37 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Oct 27, 2010 | Option Exercise | $7.60 | 326,288 | 2,479,789 | 684,836 | Oct 27, 2010, 05:37 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Oct 27, 2010 | Buy | $9.50 | 105,473 | 1,001,994 | 1,116,597 | Oct 27, 2010, 05:37 PM |
| ADVENT HEALTHCARE & LIFE SCIENCES III LIMITED PARTNERSHIP | Member of Group > 10% | Oct 27, 2010 | Buy | $9.50 | 105,473 | 1,001,994 | 1,011,124 | Oct 27, 2010, 05:37 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Oct 27, 2010 | Option Exercise | $7.60 | 805,140 | 6,119,064 | 2,495,111 | Oct 27, 2010, 05:36 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Oct 27, 2010 | Option Exercise | $7.60 | 805,140 | 6,119,064 | 1,689,971 | Oct 27, 2010, 05:36 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Oct 27, 2010 | Buy | $9.50 | 260,263 | 2,472,499 | 2,755,374 | Oct 27, 2010, 05:36 PM |
| AHLS III GP LIMITED PARTNERSHIP | Member of Group > 10% | Oct 27, 2010 | Buy | $9.50 | 260,263 | 2,472,499 | 2,495,111 | Oct 27, 2010, 05:36 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Oct 27, 2010 | Option Exercise | $7.60 | 805,140 | 6,119,064 | 1,689,971 | Oct 27, 2010, 05:35 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Oct 27, 2010 | Option Exercise | $7.60 | 805,140 | 6,119,064 | 2,495,111 | Oct 27, 2010, 05:35 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Oct 27, 2010 | Buy | $9.50 | 260,263 | 2,472,499 | 2,755,374 | Oct 27, 2010, 05:35 PM |
| ADVENT INTERNATIONAL LLC | Member of Group > 10% | Oct 27, 2010 | Buy | $9.50 | 260,263 | 2,472,499 | 2,495,111 | Oct 27, 2010, 05:35 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Oct 27, 2010 | Option Exercise | $7.60 | 814,092 | 6,187,099 | 2,522,952 | Oct 27, 2010, 05:34 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Oct 27, 2010 | Option Exercise | $7.60 | 814,092 | 6,187,099 | 1,708,860 | Oct 27, 2010, 05:34 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Oct 27, 2010 | Buy | $9.50 | 263,158 | 2,500,001 | 2,786,110 | Oct 27, 2010, 05:34 PM |
| ADVENT INTERNATIONAL CORP/MA | Member of Group > 10% | Oct 27, 2010 | Buy | $9.50 | 263,158 | 2,500,001 | 2,522,952 | Oct 27, 2010, 05:34 PM |
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