. (THLD)

$0 0 (0.00%)

Market Cap: $0

As of 12/31/69 07:00 PM EST. Market closed.

(THLD)

. (THLD)

$0 0 (0.00%)

Market Cap: $0

As of 12/31/69 07:00 PM EST. Market closed.

COMPANY PROFILE
Sector
Industry
URL
Address
.
Sector
Industry
URL
Address
.
KEY STATS
Open
$0
Previous Close
$0
Days Range
$0 - $0
52 week range
$0 - $0
Volume
0
Avg. Volume (30 days)
0
Market Cap
$0
Dividend Yield
0.00%
P/E
-
Shares Outstanding
0
Open
$0
Previous Close
$0
Days Range
$0 - $0
52 week range
$0 - $0
Volume
0
Avg. Volume (30 days)
0
Market Cap
$0
Dividend Yield
0.00%
P/E
-
Shares Outstanding
0

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

INSIDER TRANSACTIONS FOR
Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
BIOTECH TARGET N V 10% Owner Sep 21, 2021 Buy $6.00 750,000 4,500,000 10,792,003 Sep 23, 2021, 11:50 AM
BIOTECH TARGET N V 10% Owner Sep 16, 2021 Buy $6.13 100,000 613,000 10,042,003 Sep 20, 2021, 12:17 PM
BIOTECH TARGET N V 10% Owner Jul 27, 2021 Buy $7.09 75,000 531,840 9,942,003 Jul 28, 2021, 12:23 PM
BIOTECH TARGET N V 10% Owner Jul 26, 2021 Buy $7.00 80,000 559,816 9,867,003 Jul 28, 2021, 12:23 PM
BIOTECH TARGET N V 10% Owner Jul 19, 2021 Buy $6.96 119,382 830,827 9,662,003 Jul 21, 2021, 02:02 PM
BIOTECH TARGET N V 10% Owner Jul 20, 2021 Buy $7.13 125,000 891,675 9,787,003 Jul 21, 2021, 02:02 PM
Poma Eric E See remarks Jul 06, 2021 Option Exercise $0.71 3,563 2,530 243,459 Jul 07, 2021, 07:30 AM
Kim Jason S. See remarks Jun 28, 2021 Option Exercise $0.71 32,038 22,747 86,174 Jun 29, 2021, 08:59 PM
Kim Jason S. See remarks Jun 28, 2021 Sale $8.36 2,770 23,157 83,404 Jun 29, 2021, 08:59 PM
BIOTECH TARGET N V 10% Owner Apr 19, 2021 Buy $8.08 40,852 329,941 9,542,621 Apr 21, 2021, 11:22 AM
BIOTECH TARGET N V 10% Owner Apr 15, 2021 Buy $8.62 150,000 1,292,655 9,501,769 Apr 19, 2021, 01:14 PM
BIOTECH TARGET N V 10% Owner Apr 12, 2021 Buy $8.02 50,000 400,830 9,101,769 Apr 13, 2021, 03:51 PM
BIOTECH TARGET N V 10% Owner Apr 09, 2021 Buy $8.23 235,664 1,939,633 9,051,769 Apr 13, 2021, 03:51 PM
BIOTECH TARGET N V 10% Owner Apr 08, 2021 Buy $8.22 300,000 2,466,660 8,816,105 Apr 09, 2021, 01:52 PM
BIOTECH TARGET N V 10% Owner Apr 07, 2021 Buy $8.24 200,000 1,648,160 8,516,105 Apr 09, 2021, 01:52 PM
BIOTECH TARGET N V 10% Owner Mar 29, 2021 Buy $11.45 80,000 915,848 8,116,105 Mar 31, 2021, 01:44 PM
BIOTECH TARGET N V 10% Owner Feb 23, 2021 Buy $11.29 235,004 2,653,031 7,961,105 Feb 25, 2021, 02:46 PM
BIOTECH TARGET N V 10% Owner Feb 24, 2021 Buy $11.48 75,000 860,835 8,036,105 Feb 25, 2021, 02:46 PM
BIOTECH TARGET N V 10% Owner Feb 18, 2021 Buy $12.65 1,185,770 14,999,990 7,726,101 Feb 19, 2021, 05:28 PM
BIOTECH TARGET N V 10% Owner Feb 01, 2021 Buy $11.69 80,000 935,344 6,540,331 Feb 03, 2021, 01:33 PM
BIOTECH TARGET N V 10% Owner Jan 29, 2021 Buy $11.94 80,000 955,000 6,460,331 Feb 01, 2021, 04:58 PM
BIOTECH TARGET N V 10% Owner Dec 10, 2020 Buy $8.28 320,000 2,649,841 6,380,331 Dec 11, 2020, 12:36 PM
BIOTECH TARGET N V 10% Owner Dec 09, 2020 Buy $8.62 125,000 1,077,600 6,060,331 Dec 11, 2020, 12:36 PM
BIOTECH TARGET N V 10% Owner Nov 10, 2020 Buy $9.16 80,000 732,472 5,935,331 Nov 12, 2020, 06:30 AM
BIOTECH TARGET N V 10% Owner Nov 09, 2020 Buy $9.05 80,000 724,144 5,855,331 Nov 12, 2020, 06:30 AM
BIOTECH TARGET N V 10% Owner Nov 06, 2020 Buy $8.33 470,335 3,919,960 5,775,331 Nov 09, 2020, 04:09 PM
BIOTECH TARGET N V 10% Owner Nov 05, 2020 Buy $10.86 75,000 814,230 5,304,996 Nov 09, 2020, 04:09 PM
BIOTECH TARGET N V 10% Owner Oct 30, 2020 Buy $8.83 80,000 706,312 5,229,996 Nov 04, 2020, 03:05 PM
BIOTECH TARGET N V 10% Owner Oct 28, 2020 Buy $9.40 80,000 751,688 5,149,996 Nov 04, 2020, 03:05 PM
LALANDE KEVIN M. Director Sep 16, 2020 Sale $13.05 500,000 6,525,000 6,097,298 Sep 18, 2020, 04:39 PM
SHV Management Services, LLC 10% Owner Sep 16, 2020 Sale $13.05 500,000 6,525,000 6,097,298 Sep 18, 2020, 04:38 PM
Longitude Capital Partners III, LLC 10% Owner Aug 28, 2020 Sale $10.75 3,496 37,568 0 Sep 01, 2020, 07:33 PM
LALANDE KEVIN M. Director May 20, 2020 Sale $16.51 300,000 4,953,000 6,597,298 May 22, 2020, 04:17 PM
SHV Management Services, LLC 10% Owner May 20, 2020 Sale $16.51 300,000 4,953,000 6,597,298 May 22, 2020, 04:16 PM
Kim Jason S. See Remarks Jan 03, 2020 Option Exercise $0.42 54,136 22,737 54,136 Jan 03, 2020, 04:41 PM
Hirsch David Director Nov 25, 2019 Buy $8.00 937,500 7,500,000 4,199,035 Dec 05, 2019, 04:16 PM
Longitude Capital Partners III, LLC 10% Owner Nov 25, 2019 Buy $8.00 937,500 7,500,000 4,199,035 Dec 05, 2019, 04:16 PM
Longitude Capital Partners III, LLC 10% Owner Nov 25, 2019 Buy $8.00 937,000 7,496,000 4,198,535 Nov 27, 2019, 04:47 PM
Hirsch David Director Nov 25, 2019 Buy $8.00 937,000 7,496,000 4,198,535 Nov 27, 2019, 04:43 PM
Morenstein Scott D Director Nov 21, 2019 Buy $8.00 468,750 3,750,000 2,052,991 Nov 25, 2019, 04:24 PM
CDK ASSOCIATES, L.L.C. Director Dec 26, 2018 Buy $3.45 25,000 86,250 1,584,241 Dec 28, 2018, 05:30 PM
Poma Eric E See Remarks Nov 26, 2018 Option Exercise $0.53 239,896 125,972 239,896 Nov 29, 2018, 05:34 PM
Morenstein Scott D Director Sep 25, 2018 Buy $5.50 545,454 2,999,997 1,559,241 Sep 27, 2018, 03:11 PM
Longitude Capital Partners III, LLC 10% Owner Sep 21, 2018 Buy $5.50 365,000 2,007,500 3,261,535 Sep 25, 2018, 04:43 PM
Hirsch David Director Sep 21, 2018 Buy $5.50 365,000 2,007,500 3,261,535 Sep 25, 2018, 04:18 PM
BIRD JEFFREY W Director Jun 01, 2017 Buy $0.57 37,626 21,349 377,782 Jun 02, 2017, 06:17 PM
BIRD JEFFREY W Director Jun 01, 2017 Buy $0.57 473,077 268,424 3,940,573 Jun 02, 2017, 06:17 PM
Fernandes Joel A Senior Vice President Sep 28, 2015 Buy $3.96 3,562 14,106 28,120 Apr 29, 2016, 04:03 PM
PARKER GEORGE GC Director Mar 18, 2015 Option Exercise $1.30 2,500 3,250 8,572 Mar 17, 2016, 04:14 PM
JAEGER WILFRED E Director Feb 18, 2015 Buy $3.74 25,000 93,625 80,000 Feb 20, 2015, 12:47 PM
Davar Nipun Vice President Oct 13, 2014 Buy $2.98 3,000 8,955 3,000 Oct 14, 2014, 06:58 PM
YOUNGER WILLIAM H JR 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:10 PM
YOUNGER WILLIAM H JR 10% Owner Oct 01, 2014 Sale $3.77 1,332 5,024 89,275 Oct 03, 2014, 07:10 PM
YOUNGER WILLIAM H JR 10% Owner Oct 01, 2014 Sale $3.77 14,407 54,343 112,480 Oct 03, 2014, 07:10 PM
YOUNGER WILLIAM H JR 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:10 PM
YOUNGER WILLIAM H JR 10% Owner Oct 01, 2014 Option Exercise $2.05 2,452 5,027 90,607 Oct 03, 2014, 07:10 PM
YOUNGER WILLIAM H JR 10% Owner Oct 01, 2014 Option Exercise $2.05 26,509 54,343 126,887 Oct 03, 2014, 07:10 PM
WHITE JAMES N 10% Owner Oct 01, 2014 Sale $3.77 12,881 48,587 264,669 Oct 03, 2014, 07:09 PM
WHITE JAMES N 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:09 PM
WHITE JAMES N 10% Owner Oct 01, 2014 Option Exercise $2.05 23,704 48,593 277,550 Oct 03, 2014, 07:09 PM
WHITE JAMES N 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:09 PM
SWEET DAVID E 10% Owner Oct 01, 2014 Sale $3.77 2,064 7,785 39,795 Oct 03, 2014, 07:09 PM
SWEET DAVID E 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:09 PM
SWEET DAVID E 10% Owner Oct 01, 2014 Sale $3.77 433 1,633 11,312 Oct 03, 2014, 07:09 PM
SWEET DAVID E 10% Owner Oct 01, 2014 Option Exercise $2.05 3,798 7,786 41,859 Oct 03, 2014, 07:09 PM
SWEET DAVID E 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:09 PM
SWEET DAVID E 10% Owner Oct 01, 2014 Option Exercise $2.05 797 1,634 11,745 Oct 03, 2014, 07:09 PM
Speiser Michael L 10% Owner Oct 01, 2014 Sale $3.77 571 2,154 11,884 Oct 03, 2014, 07:03 PM
Speiser Michael L 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:03 PM
Speiser Michael L 10% Owner Oct 01, 2014 Option Exercise $2.05 1,051 2,155 12,455 Oct 03, 2014, 07:03 PM
Speiser Michael L 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:03 PM
SHEEHAN ANDREW T 10% Owner Oct 01, 2014 Sale $3.77 3,695 13,938 78,165 Oct 03, 2014, 07:03 PM
SHEEHAN ANDREW T 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:03 PM
SHEEHAN ANDREW T 10% Owner Oct 01, 2014 Option Exercise $2.05 6,802 13,944 81,860 Oct 03, 2014, 07:03 PM
SHEEHAN ANDREW T 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:03 PM
Pullara Samuel J III 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:01 PM
Pullara Samuel J III 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:01 PM
GAITHER JAMES C 10% Owner Oct 01, 2014 Sale $3.77 4,630 17,464 49,601 Oct 03, 2014, 07:01 PM
GAITHER JAMES C 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:01 PM
GAITHER JAMES C 10% Owner Oct 01, 2014 Option Exercise $2.05 8,521 17,468 54,231 Oct 03, 2014, 07:01 PM
GAITHER JAMES C 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:01 PM
Dyckerhoff Stefan A 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:01 PM
Dyckerhoff Stefan A 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:01 PM
COXE TENCH 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:01 PM
COXE TENCH 10% Owner Oct 01, 2014 Sale $3.77 5,477 20,659 294,880 Oct 03, 2014, 07:01 PM
COXE TENCH 10% Owner Oct 01, 2014 Sale $3.77 33,020 124,551 182,828 Oct 03, 2014, 07:01 PM
COXE TENCH 10% Owner Oct 01, 2014 Option Exercise $2.05 60,758 124,554 215,848 Oct 03, 2014, 07:01 PM
COXE TENCH 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:01 PM
COXE TENCH 10% Owner Oct 01, 2014 Option Exercise $2.05 10,078 20,660 300,357 Oct 03, 2014, 07:01 PM
BIRD JEFFREY W Director Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:01 PM
BIRD JEFFREY W Director Oct 01, 2014 Sale $3.77 11,863 44,747 244,146 Oct 03, 2014, 07:01 PM
BIRD JEFFREY W Director Oct 01, 2014 Option Exercise $2.05 21,829 44,749 256,009 Oct 03, 2014, 07:01 PM
BIRD JEFFREY W Director Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:01 PM
BAKER G LEONARD JR 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:01 PM
BAKER G LEONARD JR 10% Owner Oct 01, 2014 Sale $3.77 6,316 23,824 132,161 Oct 03, 2014, 07:01 PM
BAKER G LEONARD JR 10% Owner Oct 01, 2014 Sale $3.77 3,791 14,300 74,610 Oct 03, 2014, 07:01 PM
BAKER G LEONARD JR 10% Owner Oct 01, 2014 Option Exercise $2.05 11,623 23,827 138,477 Oct 03, 2014, 07:01 PM
BAKER G LEONARD JR 10% Owner Oct 01, 2014 Option Exercise $2.05 6,977 14,303 78,401 Oct 03, 2014, 07:01 PM
BAKER G LEONARD JR 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:01 PM
ANDERSON DAVID L 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:00 PM
ANDERSON DAVID L 10% Owner Oct 01, 2014 Sale $3.77 435 1,641 15,891 Oct 03, 2014, 07:00 PM
ANDERSON DAVID L 10% Owner Oct 01, 2014 Sale $3.77 2,995 11,297 37,110 Oct 03, 2014, 07:00 PM
ANDERSON DAVID L 10% Owner Oct 01, 2014 Sale $3.77 2,995 11,297 78,038 Oct 03, 2014, 07:00 PM
ANDERSON DAVID L 10% Owner Oct 01, 2014 Option Exercise $2.05 5,511 11,298 40,105 Oct 03, 2014, 07:00 PM
ANDERSON DAVID L 10% Owner Oct 01, 2014 Option Exercise $2.05 5,511 11,298 81,033 Oct 03, 2014, 07:00 PM
ANDERSON DAVID L 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:00 PM
ANDERSON DAVID L 10% Owner Oct 01, 2014 Option Exercise $2.05 801 1,642 16,326 Oct 03, 2014, 07:00 PM
SUTTER HILL VENTURES 10% Owner Oct 01, 2014 Sale $3.77 226,657 854,950 4,715,398 Oct 03, 2014, 07:00 PM
SUTTER HILL VENTURES 10% Owner Oct 01, 2014 Option Exercise $2.05 417,050 854,952 4,942,055 Oct 03, 2014, 07:00 PM
SELICK HAROLD E Chief Executive Officer Oct 02, 2014 Option Exercise $2.05 20,942 42,931 433,870 Oct 03, 2014, 05:17 PM
YOUNGER WILLIAM H JR 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:11 PM
YOUNGER WILLIAM H JR 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:11 PM
WHITE JAMES N 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:11 PM
WHITE JAMES N 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:11 PM
SWEET DAVID E 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:11 PM
SWEET DAVID E 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:11 PM
SUTTER HILL ENTREPRENEURS FUND QP LP 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:10 PM
SUTTER HILL ENTREPRENEURS FUND AI LP 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:10 PM
Speiser Michael L 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:10 PM
Speiser Michael L 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:10 PM
SHEEHAN ANDREW T 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:10 PM
SHEEHAN ANDREW T 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:10 PM
Pullara Samuel J III 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:10 PM
Pullara Samuel J III 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:10 PM
GAITHER JAMES C 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:09 PM
GAITHER JAMES C 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:09 PM
Dyckerhoff Stefan A 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:09 PM
Dyckerhoff Stefan A 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:09 PM
COXE TENCH 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:09 PM
COXE TENCH 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:09 PM
BIRD JEFFREY W Director Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:09 PM
BIRD JEFFREY W Director Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:09 PM
BAKER G LEONARD JR 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:09 PM
BAKER G LEONARD JR 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:09 PM
ANDERSON DAVID L 10% Owner Jun 20, 2014 Sale $4.01 3,960 15,872 0 Jun 23, 2014, 06:09 PM
ANDERSON DAVID L 10% Owner Jun 20, 2014 Sale $4.01 10,028 40,193 0 Jun 23, 2014, 06:09 PM
JAEGER WILFRED E Director Jan 16, 2014 Sale $4.86 96,356 467,972 0 Jan 17, 2014, 07:15 PM
JAEGER WILFRED E Director Jan 14, 2014 Sale $4.87 98,000 476,868 281,245 Jan 15, 2014, 05:06 PM
JAEGER WILFRED E Director Jan 13, 2014 Sale $4.89 126,956 621,450 374,245 Jan 15, 2014, 05:06 PM
JAEGER WILFRED E Director Jan 15, 2014 Sale $4.86 200,000 971,400 91,449 Jan 15, 2014, 05:06 PM
JAEGER WILFRED E Director Jan 08, 2014 Sale $4.90 243,900 1,194,744 950,234 Jan 10, 2014, 05:33 PM
JAEGER WILFRED E Director Jan 10, 2014 Sale $4.87 280,000 1,364,076 494,724 Jan 10, 2014, 05:33 PM
JAEGER WILFRED E Director Jan 09, 2014 Sale $4.87 200,000 973,500 760,438 Jan 10, 2014, 05:33 PM
JAEGER WILFRED E Director Jul 12, 2013 Sale $5.54 232,800 1,289,479 1,266,338 Jul 16, 2013, 04:53 PM
JAEGER WILFRED E Director Jul 15, 2013 Sale $5.52 89,200 492,206 1,181,690 Jul 16, 2013, 04:53 PM
JAEGER WILFRED E Director Jul 11, 2013 Sale $5.52 116,000 640,401 1,487,261 Jul 12, 2013, 02:47 PM
JAEGER WILFRED E Director Jul 10, 2013 Sale $5.50 62,000 341,068 1,597,343 Jul 12, 2013, 02:47 PM
JAEGER WILFRED E Director Jul 03, 2013 Sale $5.56 123,700 687,772 1,747,250 Jul 08, 2013, 04:31 PM
JAEGER WILFRED E Director Jul 05, 2013 Sale $5.48 95,967 525,899 1,656,180 Jul 08, 2013, 04:31 PM
JAEGER WILFRED E Director Jun 19, 2013 Sale $5.50 2,000 11,007 1,864,639 Jun 21, 2013, 05:50 PM
JAEGER WILFRED E Director Jun 18, 2013 Sale $5.50 71,511 393,411 1,866,537 Jun 19, 2013, 12:07 PM
JAEGER WILFRED E Director Jun 17, 2013 Sale $5.53 53,222 294,158 1,934,399 Jun 19, 2013, 12:07 PM
SELICK HAROLD E Chief Executive Officer Jun 17, 2013 Option Exercise $1.86 19,607 36,469 403,928 Jun 18, 2013, 07:16 PM
JAEGER WILFRED E Director Jun 10, 2013 Sale $5.50 53,600 294,816 1,984,906 Jun 11, 2013, 06:34 PM
JAEGER WILFRED E Director Jun 07, 2013 Sale $5.47 100,000 546,710 2,035,771 Jun 11, 2013, 06:34 PM
Speiser Michael L 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:32 PM
Speiser Michael L 10% Owner May 31, 2013 Sale $5.72 656 3,755 11,404 Jun 04, 2013, 05:32 PM
Speiser Michael L 10% Owner May 31, 2013 Option Exercise $1.86 2,021 3,759 12,060 Jun 04, 2013, 05:32 PM
Speiser Michael L 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:32 PM
SHEEHAN ANDREW T 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:32 PM
SHEEHAN ANDREW T 10% Owner May 31, 2013 Sale $5.72 4,773 27,321 75,058 Jun 04, 2013, 05:32 PM
SHEEHAN ANDREW T 10% Owner May 31, 2013 Option Exercise $1.86 14,691 27,325 79,831 Jun 04, 2013, 05:32 PM
SHEEHAN ANDREW T 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:32 PM
BIRD JEFFREY W Director May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:32 PM
BIRD JEFFREY W Director May 31, 2013 Sale $5.72 12,589 72,059 234,180 Jun 04, 2013, 05:32 PM
BIRD JEFFREY W Director May 31, 2013 Option Exercise $1.86 38,747 72,069 246,769 Jun 04, 2013, 05:32 PM
BIRD JEFFREY W Director May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:32 PM
WHITE JAMES N 10% Owner May 31, 2013 Sale $5.72 14,937 85,499 253,846 Jun 04, 2013, 05:31 PM
WHITE JAMES N 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:31 PM
WHITE JAMES N 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:31 PM
WHITE JAMES N 10% Owner May 31, 2013 Option Exercise $1.86 45,971 85,506 268,783 Jun 04, 2013, 05:31 PM
GAITHER JAMES C 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:30 PM
GAITHER JAMES C 10% Owner May 31, 2013 Sale $5.72 3,811 21,814 19,811 Jun 04, 2013, 05:30 PM
GAITHER JAMES C 10% Owner May 31, 2013 Sale $5.72 957 5,478 45,710 Jun 04, 2013, 05:30 PM
GAITHER JAMES C 10% Owner May 31, 2013 Option Exercise $1.86 2,947 5,481 46,667 Jun 04, 2013, 05:30 PM
GAITHER JAMES C 10% Owner May 31, 2013 Option Exercise $1.86 11,729 21,816 23,622 Jun 04, 2013, 05:30 PM
GAITHER JAMES C 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:30 PM
COXE TENCH 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:30 PM
COXE TENCH 10% Owner May 31, 2013 Sale $5.72 41,858 239,595 290,279 Jun 04, 2013, 05:30 PM
COXE TENCH 10% Owner May 31, 2013 Option Exercise $1.86 128,816 239,598 332,137 Jun 04, 2013, 05:30 PM
COXE TENCH 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:30 PM
YOUNGER WILLIAM H JR 10% Owner May 31, 2013 Sale $5.72 7,311 41,848 71,752 Jun 04, 2013, 05:30 PM
YOUNGER WILLIAM H JR 10% Owner May 31, 2013 Sale $5.72 6,371 36,468 100,378 Jun 04, 2013, 05:30 PM
YOUNGER WILLIAM H JR 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:30 PM
YOUNGER WILLIAM H JR 10% Owner May 31, 2013 Sale $5.72 1,532 8,769 88,155 Jun 04, 2013, 05:30 PM
YOUNGER WILLIAM H JR 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:30 PM
YOUNGER WILLIAM H JR 10% Owner May 31, 2013 Option Exercise $1.86 4,716 8,772 89,687 Jun 04, 2013, 05:30 PM
YOUNGER WILLIAM H JR 10% Owner May 31, 2013 Option Exercise $2.34 22,502 52,655 79,063 Jun 04, 2013, 05:30 PM
YOUNGER WILLIAM H JR 10% Owner May 31, 2013 Option Exercise $1.86 19,607 36,469 106,749 Jun 04, 2013, 05:30 PM
BAKER G LEONARD JR 10% Owner May 31, 2013 Sale $5.72 3,523 20,166 71,424 Jun 04, 2013, 05:30 PM
BAKER G LEONARD JR 10% Owner May 31, 2013 Sale $5.72 6,153 35,220 126,854 Jun 04, 2013, 05:30 PM
BAKER G LEONARD JR 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:30 PM
BAKER G LEONARD JR 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:30 PM
BAKER G LEONARD JR 10% Owner May 31, 2013 Option Exercise $1.86 10,844 20,170 74,947 Jun 04, 2013, 05:30 PM
BAKER G LEONARD JR 10% Owner May 31, 2013 Option Exercise $1.86 18,939 35,227 133,007 Jun 04, 2013, 05:30 PM
Dyckerhoff Stefan A 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:29 PM
Dyckerhoff Stefan A 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:29 PM
SWEET DAVID E 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:29 PM
SWEET DAVID E 10% Owner May 31, 2013 Sale $5.72 497 2,845 10,948 Jun 04, 2013, 05:29 PM
SWEET DAVID E 10% Owner May 31, 2013 Sale $5.72 1,905 10,904 38,061 Jun 04, 2013, 05:29 PM
SWEET DAVID E 10% Owner May 31, 2013 Option Exercise $1.86 5,864 10,907 39,966 Jun 04, 2013, 05:29 PM
SWEET DAVID E 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:29 PM
SWEET DAVID E 10% Owner May 31, 2013 Option Exercise $1.86 1,532 2,850 11,445 Jun 04, 2013, 05:29 PM
Pullara Samuel J III 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:29 PM
Pullara Samuel J III 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:29 PM
SUTTER HILL VENTURES 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:28 PM
SUTTER HILL VENTURES 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:28 PM
ANDERSON DAVID L 10% Owner May 31, 2013 Sale $5.72 5,450 31,196 75,522 Jun 04, 2013, 05:28 PM
ANDERSON DAVID L 10% Owner May 31, 2013 Sale $5.72 500 2,862 15,525 Jun 04, 2013, 05:28 PM
ANDERSON DAVID L 10% Owner May 31, 2013 Sale $5.72 260,592 1,491,629 4,525,005 Jun 04, 2013, 05:28 PM
ANDERSON DAVID L 10% Owner May 31, 2013 Option Exercise $1.86 1,540 2,864 16,025 Jun 04, 2013, 05:28 PM
ANDERSON DAVID L 10% Owner May 31, 2013 Option Exercise $1.86 801,952 1,491,631 4,785,597 Jun 04, 2013, 05:28 PM
ANDERSON DAVID L 10% Owner May 31, 2013 Option Exercise $1.86 16,773 31,198 80,972 Jun 04, 2013, 05:28 PM
Pearce Tillman Chief Medical Officer May 22, 2013 Option Exercise $3.46 20,000 69,200 20,000 May 24, 2013, 02:13 PM
Pearce Tillman Chief Medical Officer May 22, 2013 Sale $5.63 20,000 112,660 0 May 24, 2013, 02:13 PM
PARKER GEORGE GC Director Oct 11, 2012 Option Exercise $1.78 22,500 40,000 28,572 Oct 15, 2012, 07:58 PM
PARKER GEORGE GC Director Oct 11, 2012 Sale $5.65 22,500 127,100 6,072 Oct 15, 2012, 07:58 PM
JAEGER WILFRED E Director Sep 04, 2012 Option Exercise $1.48 55,000 81,150 55,000 Sep 06, 2012, 08:27 PM
Fernandes Joel A VP, Finance and Controller Aug 24, 2012 Sale $8.10 9,500 76,950 18,558 Aug 28, 2012, 06:14 PM
JAEGER WILFRED E Director Aug 27, 2012 Sale $7.98 286,400 2,284,727 2,129,669 Aug 27, 2012, 07:29 PM
JAEGER WILFRED E Director Aug 24, 2012 Sale $8.02 500,000 4,011,150 2,401,457 Aug 27, 2012, 07:29 PM
JAEGER WILFRED E Director Aug 22, 2012 Sale $7.52 59,600 447,966 2,875,947 Aug 23, 2012, 04:06 PM
JAEGER WILFRED E Director Aug 21, 2012 Sale $7.50 30,000 225,000 2,932,557 Aug 23, 2012, 04:06 PM
JAEGER WILFRED E Director Aug 09, 2012 Option Exercise $1.96 811,003 1,588,046 2,961,026 Aug 10, 2012, 04:35 PM
JAEGER WILFRED E Director Jul 13, 2012 Sale $8.01 125,000 1,001,662 2,191,399 Jul 17, 2012, 05:24 PM
Frazier Healthcare VI, L.P. 10% Owner Feb 21, 2012 Sale $5.88 4,579,081 26,907,609 3,550,239 Feb 23, 2012, 04:29 PM
Frazier Healthcare VI, L.P. 10% Owner Feb 21, 2012 Sale $5.88 9,158,162 53,815,218 3,550,239 Feb 23, 2012, 04:29 PM
Frazier Healthcare VI, L.P. 10% Owner Feb 07, 2012 Sale $3.02 300,000 906,000 4,579,081 Feb 08, 2012, 04:47 PM
Frazier Healthcare VI, L.P. 10% Owner Feb 07, 2012 Sale $3.02 600,000 1,812,000 4,579,081 Feb 08, 2012, 04:47 PM
Frazier Healthcare VI, L.P. 10% Owner Mar 16, 2011 Buy $2.05 952,380 1,952,379 4,879,081 Mar 16, 2011, 09:06 PM
Frazier Healthcare VI, L.P. 10% Owner Mar 16, 2011 Buy $2.05 1,904,760 3,904,758 4,879,081 Mar 16, 2011, 09:06 PM
SUTTER HILL VENTURES 10% Owner Mar 11, 2011 Buy $2.10 690,969 1,451,035 4,369,952 Mar 15, 2011, 09:56 PM
SUTTER HILL VENTURES 10% Owner Mar 11, 2011 Buy $2.10 690,969 1,451,035 4,369,952 Mar 15, 2011, 09:13 PM
YOUNGER WILLIAM H JR 10% Owner Mar 11, 2011 Buy $2.10 40,039 84,082 61,546 Mar 15, 2011, 07:06 PM
WHITE JAMES N 10% Owner Mar 11, 2011 Buy $2.10 22,727 47,727 140,119 Mar 15, 2011, 07:04 PM
SWEET DAVID E 10% Owner Mar 11, 2011 Buy $2.10 5,738 12,050 34,102 Mar 15, 2011, 07:03 PM
SHEEHAN ANDREW T 10% Owner Mar 11, 2011 Buy $2.10 7,948 16,691 50,428 Mar 15, 2011, 07:00 PM
SELICK HAROLD E Chief Executive Officer Mar 11, 2011 Buy $2.10 47,619 100,000 372,321 Mar 15, 2011, 06:59 PM
Curd John G President and CMO Mar 11, 2011 Buy $2.10 11,904 24,998 127,841 Mar 15, 2011, 06:59 PM
Fernandes Joel A Sr Director Finance/Controller Mar 11, 2011 Buy $2.10 7,142 14,998 19,059 Mar 15, 2011, 06:58 PM
SANDS GREGORY P 10% Owner Mar 11, 2011 Buy $2.10 14,910 31,311 90,583 Mar 15, 2011, 06:58 PM
GAITHER JAMES C 10% Owner Mar 11, 2011 Buy $2.10 5,278 11,084 29,079 Mar 15, 2011, 06:56 PM
GAITHER JAMES C 10% Owner Mar 11, 2011 Buy $2.10 5,278 11,084 11,893 Mar 15, 2011, 06:56 PM
COXE TENCH 10% Owner Mar 11, 2011 Buy $2.10 91,766 192,709 91,766 Mar 15, 2011, 06:53 PM
BIRD JEFFREY W Director Mar 11, 2011 Buy $2.10 20,962 44,020 132,078 Mar 15, 2011, 06:51 PM
BAKER G LEONARD JR 10% Owner Mar 11, 2011 Buy $2.10 13,970 29,337 91,391 Mar 15, 2011, 06:50 PM
BAKER G LEONARD JR 10% Owner Mar 11, 2011 Buy $2.10 10,538 22,130 64,103 Mar 15, 2011, 06:50 PM
ANDERSON DAVID L 10% Owner Mar 11, 2011 Buy $2.10 16,649 34,963 34,594 Mar 15, 2011, 06:46 PM
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Buy Sale Option Exercise
Owner Relationship Date Value($)
BIOTECH TARGET N V 10% Owner 09/21/2021 4,500,000
BIOTECH TARGET N V 10% Owner 09/16/2021 613,000
BIOTECH TARGET N V 10% Owner 07/27/2021 531,840
BIOTECH TARGET N V 10% Owner 07/26/2021 559,816
BIOTECH TARGET N V 10% Owner 07/19/2021 830,827
BIOTECH TARGET N V 10% Owner 07/20/2021 891,675
Poma Eric E See remarks 07/06/2021 2,530
Kim Jason S. See remarks 06/28/2021 22,747
Kim Jason S. See remarks 06/28/2021 23,157
BIOTECH TARGET N V 10% Owner 04/19/2021 329,941
BIOTECH TARGET N V 10% Owner 04/15/2021 1,292,655
BIOTECH TARGET N V 10% Owner 04/12/2021 400,830
BIOTECH TARGET N V 10% Owner 04/09/2021 1,939,633
BIOTECH TARGET N V 10% Owner 04/08/2021 2,466,660
BIOTECH TARGET N V 10% Owner 04/07/2021 1,648,160
BIOTECH TARGET N V 10% Owner 03/29/2021 915,848
BIOTECH TARGET N V 10% Owner 02/23/2021 2,653,031
BIOTECH TARGET N V 10% Owner 02/24/2021 860,835
BIOTECH TARGET N V 10% Owner 02/18/2021 14,999,990
BIOTECH TARGET N V 10% Owner 02/01/2021 935,344
BIOTECH TARGET N V 10% Owner 01/29/2021 955,000
BIOTECH TARGET N V 10% Owner 12/10/2020 2,649,841
BIOTECH TARGET N V 10% Owner 12/09/2020 1,077,600
BIOTECH TARGET N V 10% Owner 11/10/2020 732,472
BIOTECH TARGET N V 10% Owner 11/09/2020 724,144
BIOTECH TARGET N V 10% Owner 11/06/2020 3,919,960
BIOTECH TARGET N V 10% Owner 11/05/2020 814,230
BIOTECH TARGET N V 10% Owner 10/30/2020 706,312
BIOTECH TARGET N V 10% Owner 10/28/2020 751,688
LALANDE KEVIN M. Director 09/16/2020 6,525,000
SHV Management Services, LLC 10% Owner 09/16/2020 6,525,000
Longitude Capital Partners III, LLC 10% Owner 08/28/2020 37,568
LALANDE KEVIN M. Director 05/20/2020 4,953,000
SHV Management Services, LLC 10% Owner 05/20/2020 4,953,000
Kim Jason S. See Remarks 01/03/2020 22,737
Hirsch David Director 11/25/2019 7,500,000
Longitude Capital Partners III, LLC 10% Owner 11/25/2019 7,500,000
Longitude Capital Partners III, LLC 10% Owner 11/25/2019 7,496,000
Hirsch David Director 11/25/2019 7,496,000
Morenstein Scott D Director 11/21/2019 3,750,000
CDK ASSOCIATES, L.L.C. Director 12/26/2018 86,250
Poma Eric E See Remarks 11/26/2018 125,972
Morenstein Scott D Director 09/25/2018 2,999,997
Longitude Capital Partners III, LLC 10% Owner 09/21/2018 2,007,500
Hirsch David Director 09/21/2018 2,007,500
BIRD JEFFREY W Director 06/01/2017 21,349
BIRD JEFFREY W Director 06/01/2017 268,424
Fernandes Joel A Senior Vice President 09/28/2015 14,106
PARKER GEORGE GC Director 03/18/2015 3,250
JAEGER WILFRED E Director 02/18/2015 93,625
Davar Nipun Vice President 10/13/2014 8,955
YOUNGER WILLIAM H JR 10% Owner 10/01/2014 854,950
YOUNGER WILLIAM H JR 10% Owner 10/01/2014 5,024
YOUNGER WILLIAM H JR 10% Owner 10/01/2014 54,343
YOUNGER WILLIAM H JR 10% Owner 10/01/2014 854,952
YOUNGER WILLIAM H JR 10% Owner 10/01/2014 5,027
YOUNGER WILLIAM H JR 10% Owner 10/01/2014 54,343
WHITE JAMES N 10% Owner 10/01/2014 48,587
WHITE JAMES N 10% Owner 10/01/2014 854,950
WHITE JAMES N 10% Owner 10/01/2014 48,593
WHITE JAMES N 10% Owner 10/01/2014 854,952
SWEET DAVID E 10% Owner 10/01/2014 7,785
SWEET DAVID E 10% Owner 10/01/2014 854,950
SWEET DAVID E 10% Owner 10/01/2014 1,633
SWEET DAVID E 10% Owner 10/01/2014 7,786
SWEET DAVID E 10% Owner 10/01/2014 854,952
SWEET DAVID E 10% Owner 10/01/2014 1,634
Speiser Michael L 10% Owner 10/01/2014 2,154
Speiser Michael L 10% Owner 10/01/2014 854,950
Speiser Michael L 10% Owner 10/01/2014 2,155
Speiser Michael L 10% Owner 10/01/2014 854,952
SHEEHAN ANDREW T 10% Owner 10/01/2014 13,938
SHEEHAN ANDREW T 10% Owner 10/01/2014 854,950
SHEEHAN ANDREW T 10% Owner 10/01/2014 13,944
SHEEHAN ANDREW T 10% Owner 10/01/2014 854,952
Pullara Samuel J III 10% Owner 10/01/2014 854,950
Pullara Samuel J III 10% Owner 10/01/2014 854,952
GAITHER JAMES C 10% Owner 10/01/2014 17,464
GAITHER JAMES C 10% Owner 10/01/2014 854,950
GAITHER JAMES C 10% Owner 10/01/2014 17,468
GAITHER JAMES C 10% Owner 10/01/2014 854,952
Dyckerhoff Stefan A 10% Owner 10/01/2014 854,950
Dyckerhoff Stefan A 10% Owner 10/01/2014 854,952
COXE TENCH 10% Owner 10/01/2014 854,950
COXE TENCH 10% Owner 10/01/2014 20,659
COXE TENCH 10% Owner 10/01/2014 124,551
COXE TENCH 10% Owner 10/01/2014 124,554
COXE TENCH 10% Owner 10/01/2014 854,952
COXE TENCH 10% Owner 10/01/2014 20,660
BIRD JEFFREY W Director 10/01/2014 854,950
BIRD JEFFREY W Director 10/01/2014 44,747
BIRD JEFFREY W Director 10/01/2014 44,749
BIRD JEFFREY W Director 10/01/2014 854,952
BAKER G LEONARD JR 10% Owner 10/01/2014 854,950
BAKER G LEONARD JR 10% Owner 10/01/2014 23,824
BAKER G LEONARD JR 10% Owner 10/01/2014 14,300
BAKER G LEONARD JR 10% Owner 10/01/2014 23,827
BAKER G LEONARD JR 10% Owner 10/01/2014 14,303
BAKER G LEONARD JR 10% Owner 10/01/2014 854,952
ANDERSON DAVID L 10% Owner 10/01/2014 854,950
ANDERSON DAVID L 10% Owner 10/01/2014 1,641
ANDERSON DAVID L 10% Owner 10/01/2014 11,297
ANDERSON DAVID L 10% Owner 10/01/2014 11,297
ANDERSON DAVID L 10% Owner 10/01/2014 11,298
ANDERSON DAVID L 10% Owner 10/01/2014 11,298
ANDERSON DAVID L 10% Owner 10/01/2014 854,952
ANDERSON DAVID L 10% Owner 10/01/2014 1,642
SUTTER HILL VENTURES 10% Owner 10/01/2014 854,950
SUTTER HILL VENTURES 10% Owner 10/01/2014 854,952
SELICK HAROLD E Chief Executive Officer 10/02/2014 42,931
YOUNGER WILLIAM H JR 10% Owner 06/20/2014 40,193
YOUNGER WILLIAM H JR 10% Owner 06/20/2014 15,872
WHITE JAMES N 10% Owner 06/20/2014 40,193
WHITE JAMES N 10% Owner 06/20/2014 15,872
SWEET DAVID E 10% Owner 06/20/2014 40,193
SWEET DAVID E 10% Owner 06/20/2014 15,872
SUTTER HILL ENTREPRENEURS FUND QP LP 10% Owner 06/20/2014 40,193
SUTTER HILL ENTREPRENEURS FUND AI LP 10% Owner 06/20/2014 15,872
Speiser Michael L 10% Owner 06/20/2014 40,193
Speiser Michael L 10% Owner 06/20/2014 15,872
SHEEHAN ANDREW T 10% Owner 06/20/2014 40,193
SHEEHAN ANDREW T 10% Owner 06/20/2014 15,872
Pullara Samuel J III 10% Owner 06/20/2014 40,193
Pullara Samuel J III 10% Owner 06/20/2014 15,872
GAITHER JAMES C 10% Owner 06/20/2014 40,193
GAITHER JAMES C 10% Owner 06/20/2014 15,872
Dyckerhoff Stefan A 10% Owner 06/20/2014 40,193
Dyckerhoff Stefan A 10% Owner 06/20/2014 15,872
COXE TENCH 10% Owner 06/20/2014 40,193
COXE TENCH 10% Owner 06/20/2014 15,872
BIRD JEFFREY W Director 06/20/2014 40,193
BIRD JEFFREY W Director 06/20/2014 15,872
BAKER G LEONARD JR 10% Owner 06/20/2014 40,193
BAKER G LEONARD JR 10% Owner 06/20/2014 15,872
ANDERSON DAVID L 10% Owner 06/20/2014 15,872
ANDERSON DAVID L 10% Owner 06/20/2014 40,193
JAEGER WILFRED E Director 01/16/2014 467,972
JAEGER WILFRED E Director 01/14/2014 476,868
JAEGER WILFRED E Director 01/13/2014 621,450
JAEGER WILFRED E Director 01/15/2014 971,400
JAEGER WILFRED E Director 01/08/2014 1,194,744
JAEGER WILFRED E Director 01/10/2014 1,364,076
JAEGER WILFRED E Director 01/09/2014 973,500
JAEGER WILFRED E Director 07/12/2013 1,289,479
JAEGER WILFRED E Director 07/15/2013 492,206
JAEGER WILFRED E Director 07/11/2013 640,401
JAEGER WILFRED E Director 07/10/2013 341,068
JAEGER WILFRED E Director 07/03/2013 687,772
JAEGER WILFRED E Director 07/05/2013 525,899
JAEGER WILFRED E Director 06/19/2013 11,007
JAEGER WILFRED E Director 06/18/2013 393,411
JAEGER WILFRED E Director 06/17/2013 294,158
SELICK HAROLD E Chief Executive Officer 06/17/2013 36,469
JAEGER WILFRED E Director 06/10/2013 294,816
JAEGER WILFRED E Director 06/07/2013 546,710
Speiser Michael L 10% Owner 05/31/2013 1,491,629
Speiser Michael L 10% Owner 05/31/2013 3,755
Speiser Michael L 10% Owner 05/31/2013 3,759
Speiser Michael L 10% Owner 05/31/2013 1,491,631
SHEEHAN ANDREW T 10% Owner 05/31/2013 1,491,629
SHEEHAN ANDREW T 10% Owner 05/31/2013 27,321
SHEEHAN ANDREW T 10% Owner 05/31/2013 27,325
SHEEHAN ANDREW T 10% Owner 05/31/2013 1,491,631
BIRD JEFFREY W Director 05/31/2013 1,491,629
BIRD JEFFREY W Director 05/31/2013 72,059
BIRD JEFFREY W Director 05/31/2013 72,069
BIRD JEFFREY W Director 05/31/2013 1,491,631
WHITE JAMES N 10% Owner 05/31/2013 85,499
WHITE JAMES N 10% Owner 05/31/2013 1,491,629
WHITE JAMES N 10% Owner 05/31/2013 1,491,631
WHITE JAMES N 10% Owner 05/31/2013 85,506
GAITHER JAMES C 10% Owner 05/31/2013 1,491,629
GAITHER JAMES C 10% Owner 05/31/2013 21,814
GAITHER JAMES C 10% Owner 05/31/2013 5,478
GAITHER JAMES C 10% Owner 05/31/2013 5,481
GAITHER JAMES C 10% Owner 05/31/2013 21,816
GAITHER JAMES C 10% Owner 05/31/2013 1,491,631
COXE TENCH 10% Owner 05/31/2013 1,491,629
COXE TENCH 10% Owner 05/31/2013 239,595
COXE TENCH 10% Owner 05/31/2013 239,598
COXE TENCH 10% Owner 05/31/2013 1,491,631
YOUNGER WILLIAM H JR 10% Owner 05/31/2013 41,848
YOUNGER WILLIAM H JR 10% Owner 05/31/2013 36,468
YOUNGER WILLIAM H JR 10% Owner 05/31/2013 1,491,629
YOUNGER WILLIAM H JR 10% Owner 05/31/2013 8,769
YOUNGER WILLIAM H JR 10% Owner 05/31/2013 1,491,631
YOUNGER WILLIAM H JR 10% Owner 05/31/2013 8,772
YOUNGER WILLIAM H JR 10% Owner 05/31/2013 52,655
YOUNGER WILLIAM H JR 10% Owner 05/31/2013 36,469
BAKER G LEONARD JR 10% Owner 05/31/2013 20,166
BAKER G LEONARD JR 10% Owner 05/31/2013 35,220
BAKER G LEONARD JR 10% Owner 05/31/2013 1,491,629
BAKER G LEONARD JR 10% Owner 05/31/2013 1,491,631
BAKER G LEONARD JR 10% Owner 05/31/2013 20,170
BAKER G LEONARD JR 10% Owner 05/31/2013 35,227
Dyckerhoff Stefan A 10% Owner 05/31/2013 1,491,629
Dyckerhoff Stefan A 10% Owner 05/31/2013 1,491,631
SWEET DAVID E 10% Owner 05/31/2013 1,491,629
SWEET DAVID E 10% Owner 05/31/2013 2,845
SWEET DAVID E 10% Owner 05/31/2013 10,904
SWEET DAVID E 10% Owner 05/31/2013 10,907
SWEET DAVID E 10% Owner 05/31/2013 1,491,631
SWEET DAVID E 10% Owner 05/31/2013 2,850
Pullara Samuel J III 10% Owner 05/31/2013 1,491,629
Pullara Samuel J III 10% Owner 05/31/2013 1,491,631
SUTTER HILL VENTURES 10% Owner 05/31/2013 1,491,629
SUTTER HILL VENTURES 10% Owner 05/31/2013 1,491,631
ANDERSON DAVID L 10% Owner 05/31/2013 31,196
ANDERSON DAVID L 10% Owner 05/31/2013 2,862
ANDERSON DAVID L 10% Owner 05/31/2013 1,491,629
ANDERSON DAVID L 10% Owner 05/31/2013 2,864
ANDERSON DAVID L 10% Owner 05/31/2013 1,491,631
ANDERSON DAVID L 10% Owner 05/31/2013 31,198
Pearce Tillman Chief Medical Officer 05/22/2013 69,200
Pearce Tillman Chief Medical Officer 05/22/2013 112,660
PARKER GEORGE GC Director 10/11/2012 40,000
PARKER GEORGE GC Director 10/11/2012 127,100
JAEGER WILFRED E Director 09/04/2012 81,150
Fernandes Joel A VP, Finance and Controller 08/24/2012 76,950
JAEGER WILFRED E Director 08/27/2012 2,284,727
JAEGER WILFRED E Director 08/24/2012 4,011,150
JAEGER WILFRED E Director 08/22/2012 447,966
JAEGER WILFRED E Director 08/21/2012 225,000
JAEGER WILFRED E Director 08/09/2012 1,588,046
JAEGER WILFRED E Director 07/13/2012 1,001,662
Frazier Healthcare VI, L.P. 10% Owner 02/21/2012 26,907,609
Frazier Healthcare VI, L.P. 10% Owner 02/21/2012 53,815,218
Frazier Healthcare VI, L.P. 10% Owner 02/07/2012 906,000
Frazier Healthcare VI, L.P. 10% Owner 02/07/2012 1,812,000
Frazier Healthcare VI, L.P. 10% Owner 03/16/2011 1,952,379
Frazier Healthcare VI, L.P. 10% Owner 03/16/2011 3,904,758
SUTTER HILL VENTURES 10% Owner 03/11/2011 1,451,035
SUTTER HILL VENTURES 10% Owner 03/11/2011 1,451,035
YOUNGER WILLIAM H JR 10% Owner 03/11/2011 84,082
WHITE JAMES N 10% Owner 03/11/2011 47,727
SWEET DAVID E 10% Owner 03/11/2011 12,050
SHEEHAN ANDREW T 10% Owner 03/11/2011 16,691
SELICK HAROLD E Chief Executive Officer 03/11/2011 100,000
Curd John G President and CMO 03/11/2011 24,998
Fernandes Joel A Sr Director Finance/Controller 03/11/2011 14,998
SANDS GREGORY P 10% Owner 03/11/2011 31,311
GAITHER JAMES C 10% Owner 03/11/2011 11,084
GAITHER JAMES C 10% Owner 03/11/2011 11,084
COXE TENCH 10% Owner 03/11/2011 192,709
BIRD JEFFREY W Director 03/11/2011 44,020
BAKER G LEONARD JR 10% Owner 03/11/2011 29,337
BAKER G LEONARD JR 10% Owner 03/11/2011 22,130
ANDERSON DAVID L 10% Owner 03/11/2011 34,963
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