Sangamo Therapeutics Inc. (SGMO) NASDAQ

$3.77 -0.18 (-4.56%)

Market Cap: $579.41M

As of 05/18/22 04:00 PM EDT. Market closed.

(SGMO)

Sangamo Therapeutics Inc. (SGMO) NASDAQ

$3.77 -0.18 (-4.56%)

Market Cap: $579.41M

As of 05/18/22 04:00 PM EDT. Market closed.

Sangamo Therapeutics is committed to translating ground-breaking science into genomic medicines with the potential to transform patients' lives using gene therapy, cell therapy, and genome ... read more

Sangamo Therapeutics is committed to translating ground-breaking science into genomic medicines with the potential to transform patients' lives using gene therapy, cell therapy, and genome engineering. read less

COMPANY PROFILE
Sector
Manufacturing
Industry
Biological Product (except Diagnostic) Manufacturing
CEO
Alexander Macrae
Full Time Employees
413
CEO Compensation (Base)
$636,480
CEO Compensation (Total)
$4.10M
URL
Address
7000 Marina Blvd, California, Brisbane, 94005.
Sector
Manufacturing
Industry
Biological Product (except Diagnostic) Manufacturing
CEO
Alexander Macrae
Full Time Employees
413
CEO Compensation (Base)
$636,480
CEO Compensation (Total)
$4.10M
Address
7000 Marina Blvd, California, Brisbane, 94005.
PRICE CHART
1w
1m
3m
6m
YTD
1y
5y
MAX
From: To:
KEY STATS
Open
$3.94
Previous Close
$3.95
Days Range
$3.68 - $3.97
52 week range
$3.48 - $12.83
Volume
1,895,999
Avg. Volume (30 days)
1,532,772
Market Cap
$579.41M
Dividend Yield
0.00%
P/E
-3.29
Shares Outstanding
146,687,251
Open
$3.94
Previous Close
$3.95
Days Range
$3.68 - $3.97
52 week range
$3.48 - $12.83
Volume
1,895,999
Avg. Volume (30 days)
1,532,772
Market Cap
$579.41M
Dividend Yield
0.00%
P/E
-3.29
Shares Outstanding
146,687,251

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

INSIDER TRANSACTIONS FOR SANGAMO THERAPEUTICS INC
Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
Willoughby Scott B. SVP, Gen. Counsel & Secretary Apr 29, 2022 Option Exercise $4.15 140 581 90,709 May 03, 2022, 05:09 PM
Fontenot Jason D. SVP, Chief Scientific Officer Apr 25, 2022 Option Exercise $4.83 826 3,990 103,167 Apr 27, 2022, 05:09 PM
Duraibabu Prathyusha Vice President, Finance Apr 25, 2022 Option Exercise $4.83 662 3,197 86,772 Apr 27, 2022, 05:08 PM
Willoughby Scott B. SVP, Gen. Counsel & Secretary Apr 24, 2022 Option Exercise $4.70 3,976 18,687 90,849 Apr 26, 2022, 05:37 PM
Duraibabu Prathyusha Vice President, Finance Mar 25, 2022 Option Exercise $5.75 345 1,984 87,434 Mar 29, 2022, 04:41 PM
Willoughby Scott B. SVP, Gen. Counsel & Secretary Feb 25, 2022 Option Exercise $5.90 1,566 9,239 53,825 Mar 01, 2022, 05:21 PM
Ramelmeier Rolf Andrew EVP, Technical Operations Feb 25, 2022 Option Exercise $5.90 12,388 73,089 88,429 Mar 01, 2022, 05:19 PM
Fontenot Jason D. SVP, Chief Scientific Officer Feb 25, 2022 Option Exercise $5.90 6,248 36,863 58,893 Mar 01, 2022, 05:18 PM
Duraibabu Prathyusha Vice President, Finance Feb 25, 2022 Option Exercise $5.90 3,474 20,497 46,779 Mar 01, 2022, 05:18 PM
McClung David Mark EVP, Chief Operating Officer Feb 25, 2022 Option Exercise $5.90 4,610 27,199 125,584 Mar 01, 2022, 05:17 PM
Macrae Sandy President, CEO and Director Feb 25, 2022 Option Exercise $5.90 49,890 294,351 297,176 Mar 01, 2022, 05:16 PM
Schott Robert J. SVP, Head of Development Feb 12, 2022 Option Exercise $5.76 5,463 31,467 34,537 Feb 24, 2022, 05:32 PM
BIOGEN INC. 10% Owner Dec 28, 2021 Sale $8.51 2,764 23,522 24,152,466 Dec 30, 2021, 05:12 PM
BIOGEN INC. 10% Owner Dec 23, 2021 Sale $8.55 81,187 694,530 24,155,830 Dec 28, 2021, 08:11 AM
BIOGEN INC. 10% Owner Dec 27, 2021 Sale $8.56 600 5,136 24,155,230 Dec 28, 2021, 08:11 AM
BIOGEN INC. 10% Owner Dec 09, 2021 Sale $8.56 23,660 202,541 24,237,017 Dec 10, 2021, 04:08 PM
BIOGEN INC. 10% Owner Dec 08, 2021 Sale $8.64 75,814 654,828 24,260,677 Dec 09, 2021, 04:08 PM
BIOGEN INC. 10% Owner Dec 07, 2021 Sale $8.52 52,178 444,437 24,336,491 Dec 09, 2021, 04:08 PM
BIOGEN INC. 10% Owner Dec 01, 2021 Sale $8.52 730 6,223 24,390,543 Dec 03, 2021, 04:09 PM
BIOGEN INC. 10% Owner Dec 02, 2021 Sale $8.51 1,874 15,943 24,388,669 Dec 03, 2021, 04:09 PM
BIOGEN INC. 10% Owner Nov 26, 2021 Sale $8.60 28,884 248,434 24,391,273 Nov 30, 2021, 04:20 PM
Willoughby Scott B. SVP, Gen. Counsel & Secretary Oct 29, 2021 Option Exercise $8.12 140 1,137 54,455 Nov 03, 2021, 03:30 PM
McClung David Mark EVP, Chief Business Officer Jun 25, 2021 Option Exercise $12.02 11,525 138,531 129,294 Jun 29, 2021, 07:55 PM
Fontenot Jason D. SVP, Chief Scientific Officer Apr 25, 2021 Option Exercise $11.71 811 9,497 62,496 Apr 27, 2021, 08:49 PM
Duraibabu Prathyusha VP, PFO and PAO Apr 25, 2021 Option Exercise $11.71 662 7,752 40,128 Apr 27, 2021, 08:49 PM
Duraibabu Prathyusha VP, PFO and PAO Mar 25, 2021 Option Exercise $12.27 345 4,233 40,790 Mar 29, 2021, 07:11 PM
LOEB GARY EVP, General Counsel & Sec. Mar 23, 2021 Option Exercise $11.02 11,981 132,031 100,762 Mar 25, 2021, 07:19 PM
LOEB GARY EVP, General Counsel & Sec. Mar 23, 2021 Sale $13.13 17,524 230,042 88,781 Mar 25, 2021, 07:19 PM
Duraibabu Prathyusha VP Principal Acct. Officer Feb 25, 2021 Option Exercise $11.19 1,863 20,847 27,385 Mar 01, 2021, 09:12 PM
Ramelmeier Rolf Andrew EVP, Technical Operations Feb 25, 2021 Option Exercise $11.19 7,779 87,047 58,199 Mar 01, 2021, 09:11 PM
LOEB GARY EVP, General Counsel & Sec. Feb 25, 2021 Option Exercise $11.19 5,762 64,477 44,781 Mar 01, 2021, 09:09 PM
Macrae Sandy President and CEO Feb 25, 2021 Option Exercise $11.19 35,311 395,130 208,691 Mar 01, 2021, 09:08 PM
Macrae Sandy President and CEO Jan 24, 2021 Option Exercise $14.95 3,977 59,456 244,002 Jan 26, 2021, 08:24 PM
Ramelmeier Rolf Andrew EVP, Technical Operations Dec 31, 2020 Sale $16.74 2,464 41,247 65,978 Jan 06, 2021, 04:27 PM
Ramelmeier Rolf Andrew EVP, Technical Operations Dec 24, 2020 Sale $18.13 3,331 60,391 68,442 Dec 30, 2020, 07:51 PM
Ramasastry Saira Director Dec 17, 2020 Option Exercise $5.99 10,000 59,900 25,000 Dec 18, 2020, 07:18 PM
Ramasastry Saira Director Dec 17, 2020 Sale $13.27 10,000 132,747 15,000 Dec 18, 2020, 07:18 PM
Lee Sung EVP, Chief Financial Officer Nov 25, 2020 Option Exercise $9.77 5,042 49,260 88,708 Nov 30, 2020, 07:46 PM
Boissel Stephane EVP, Corp. Strategy Jun 04, 2020 Option Exercise $11.23 14,907 167,406 70,116 Jun 05, 2020, 09:29 PM
Duraibabu Prathyusha VP Principal Acct. Officer Apr 25, 2020 Option Exercise $8.32 647 5,383 26,603 Apr 28, 2020, 06:59 PM
DILLY STEPHEN GEORGE Director Mar 19, 2020 Option Exercise $5.42 35,000 189,700 40,000 Mar 20, 2020, 05:00 PM
DILLY STEPHEN GEORGE Director Mar 19, 2020 Sale $6.00 35,000 210,000 5,000 Mar 20, 2020, 05:00 PM
PARKER H STEWART Director Mar 18, 2020 Buy $5.20 3,000 15,585 13,000 Mar 19, 2020, 07:55 PM
Zakrzewski Joseph S Director Mar 17, 2020 Buy $4.99 5,000 24,950 30,000 Mar 19, 2020, 05:00 PM
DILLY STEPHEN GEORGE Director Mar 16, 2020 Option Exercise $5.42 15,000 81,300 20,000 Mar 18, 2020, 09:09 PM
DILLY STEPHEN GEORGE Director Mar 16, 2020 Sale $6.02 15,000 90,261 5,000 Mar 18, 2020, 09:09 PM
Zakrzewski Joseph S Director Mar 13, 2020 Buy $5.67 5,000 28,350 25,000 Mar 13, 2020, 05:41 PM
Zakrzewski Joseph S Director Mar 12, 2020 Buy $6.31 15,000 94,650 20,000 Mar 13, 2020, 05:41 PM
Ramelmeier Rolf Andrew EVP, Technical Operations Feb 25, 2020 Option Exercise $6.80 1,703 11,580 14,128 Feb 26, 2020, 07:33 PM
Boissel Stephane EVP, Corp. Strategy Feb 25, 2020 Option Exercise $6.80 2,384 16,211 15,116 Feb 26, 2020, 07:31 PM
Macrae Sandy President and CEO Feb 25, 2020 Option Exercise $6.80 7,264 49,395 79,229 Feb 26, 2020, 07:29 PM
Macrae Sandy President and CEO Jan 24, 2020 Option Exercise $7.50 4,283 32,123 86,493 Jan 28, 2020, 07:11 PM
Boissel Stephane EVP, Corp. Strat. & Int. CFO Aug 12, 2019 Option Exercise $11.23 11,137 125,069 17,500 Aug 14, 2019, 05:10 PM
Yi Kathy EVP & Chief Financial Officer May 15, 2019 Option Exercise $4.55 5,000 22,750 30,512 May 17, 2019, 05:41 PM
Yi Kathy EVP & Chief Financial Officer May 15, 2019 Sale $10.00 5,000 50,000 25,512 May 17, 2019, 05:41 PM
Yi Kathy EVP & Chief Financial Officer Apr 15, 2019 Option Exercise $4.55 5,000 22,750 30,512 Apr 16, 2019, 07:27 PM
Yi Kathy EVP & Chief Financial Officer Apr 15, 2019 Sale $12.11 5,000 60,550 25,512 Apr 16, 2019, 07:27 PM
Yi Kathy EVP & Chief Financial Officer Mar 15, 2019 Option Exercise $4.55 5,000 22,750 30,512 Mar 18, 2019, 07:35 PM
Yi Kathy EVP & Chief Financial Officer Mar 15, 2019 Sale $10.00 5,000 50,000 25,512 Mar 18, 2019, 07:35 PM
Yi Kathy EVP & Chief Financial Officer Mar 01, 2019 Option Exercise $4.55 5,000 22,750 30,512 Mar 05, 2019, 08:21 PM
Yi Kathy EVP & Chief Financial Officer Mar 01, 2019 Sale $10.00 5,000 50,000 25,512 Mar 05, 2019, 08:21 PM
Conner Edward R. Sr. VP & Chief Medical Officer Jan 24, 2019 Option Exercise $11.10 834 9,257 11,291 Jan 28, 2019, 05:46 PM
Yi Kathy SVP & Chief Financial Officer Jan 24, 2019 Option Exercise $11.10 988 10,967 6,262 Jan 28, 2019, 05:45 PM
Macrae Sandy President and CEO Jan 24, 2018 Option Exercise $11.10 3,974 44,111 27,526 Jan 28, 2019, 05:45 PM
Yi Kathy SVP & Chief Financial Officer Jan 15, 2019 Option Exercise $4.55 5,000 22,750 12,250 Jan 16, 2019, 04:08 PM
Yi Kathy SVP & Chief Financial Officer Jan 15, 2019 Sale $11.04 5,000 55,200 7,250 Jan 16, 2019, 04:08 PM
Conner Edward R. Sr. VP & Chief Medical Officer Jan 07, 2019 Option Exercise $3.20 5,000 16,000 17,125 Jan 08, 2019, 05:38 PM
Conner Edward R. Sr. VP & Chief Medical Officer Jan 07, 2019 Sale $12.33 5,000 61,631 12,125 Jan 08, 2019, 05:38 PM
Yi Kathy SVP & Chief Financial Officer Dec 17, 2018 Option Exercise $4.55 5,000 22,750 12,250 Dec 18, 2018, 05:35 PM
Yi Kathy SVP & Chief Financial Officer Dec 17, 2018 Sale $11.44 5,000 57,200 7,250 Dec 18, 2018, 05:35 PM
Conner Edward R. Sr. VP & Chief Medical Officer Dec 06, 2018 Option Exercise $3.20 5,000 16,000 17,125 Dec 07, 2018, 07:46 PM
Conner Edward R. Sr. VP & Chief Medical Officer Dec 06, 2018 Sale $11.49 5,000 57,433 12,125 Dec 07, 2018, 07:46 PM
Yi Kathy SVP & Chief Financial Officer Nov 15, 2018 Option Exercise $4.55 5,000 22,750 12,250 Nov 16, 2018, 05:16 PM
Yi Kathy SVP & Chief Financial Officer Nov 15, 2018 Sale $10.00 5,000 50,000 7,250 Nov 16, 2018, 05:16 PM
PARKER H STEWART Director Nov 14, 2018 Buy $9.00 2,000 18,002 7,500 Nov 15, 2018, 07:08 PM
Conner Edward R. Sr. VP & Chief Medical Officer Nov 06, 2018 Option Exercise $3.20 5,000 16,000 17,125 Nov 07, 2018, 05:41 PM
Conner Edward R. Sr. VP & Chief Medical Officer Nov 06, 2018 Sale $13.73 5,000 68,650 12,125 Nov 07, 2018, 05:41 PM
Yi Kathy SVP & Chief Financial Officer Oct 15, 2018 Option Exercise $4.55 5,000 22,750 12,250 Oct 16, 2018, 07:25 PM
Yi Kathy SVP & Chief Financial Officer Oct 15, 2018 Sale $13.97 5,000 69,850 7,250 Oct 16, 2018, 07:25 PM
Conner Edward R. Sr. VP & Chief Medical Officer Oct 08, 2018 Option Exercise $3.20 5,000 16,000 15,125 Oct 09, 2018, 05:40 PM
Conner Edward R. Sr. VP & Chief Medical Officer Oct 08, 2018 Sale $14.55 5,000 72,773 10,125 Oct 09, 2018, 05:40 PM
Yi Kathy SVP & Chief Financial Officer Sep 17, 2018 Option Exercise $4.55 5,000 22,750 12,250 Sep 18, 2018, 05:06 PM
Yi Kathy SVP & Chief Financial Officer Sep 17, 2018 Sale $14.66 5,000 73,285 7,250 Sep 18, 2018, 05:06 PM
JEFFS ROGER Director Sep 07, 2018 Buy $13.56 7,408 100,487 9,908 Sep 07, 2018, 07:18 PM
PARKER H STEWART Director Sep 07, 2018 Buy $13.52 2,000 27,040 5,500 Sep 07, 2018, 05:45 PM
Conner Edward R. Sr. VP & Chief Medical Officer Sep 06, 2018 Option Exercise $3.20 5,000 16,000 15,125 Sep 07, 2018, 04:39 PM
Conner Edward R. Sr. VP & Chief Medical Officer Sep 06, 2018 Sale $14.17 5,000 70,845 10,125 Sep 07, 2018, 04:39 PM
Yi Kathy SVP & Chief Financial Officer Aug 16, 2018 Option Exercise $4.55 5,000 22,750 12,250 Aug 17, 2018, 04:17 PM
Yi Kathy SVP & Chief Financial Officer Aug 16, 2018 Sale $15.39 5,000 76,951 7,250 Aug 17, 2018, 04:17 PM
Conner Edward R. Sr. VP & Chief Medical Officer Aug 06, 2018 Option Exercise $3.20 5,000 16,000 15,125 Aug 07, 2018, 07:28 PM
Conner Edward R. Sr. VP & Chief Medical Officer Aug 06, 2018 Sale $13.45 5,000 67,250 10,125 Aug 07, 2018, 07:28 PM
Yi Kathy SVP & Chief Financial Officer Jul 16, 2018 Option Exercise $4.55 5,000 22,750 12,250 Jul 17, 2018, 04:16 PM
Yi Kathy SVP & Chief Financial Officer Jul 16, 2018 Sale $14.77 5,000 73,860 7,250 Jul 17, 2018, 04:16 PM
Conner Edward R. Sr. VP & Chief Medical Officer Jul 06, 2018 Option Exercise $3.20 5,000 16,000 15,125 Jul 09, 2018, 06:58 PM
Conner Edward R. Sr. VP & Chief Medical Officer Jul 06, 2018 Sale $15.80 5,000 78,975 10,125 Jul 09, 2018, 06:58 PM
Yi Kathy SVP & Chief Financial Officer Jun 15, 2018 Option Exercise $4.55 5,000 22,750 12,250 Jun 15, 2018, 07:43 PM
Yi Kathy SVP & Chief Financial Officer Jun 15, 2018 Sale $15.67 5,000 78,365 7,250 Jun 15, 2018, 07:43 PM
Conner Edward R. Sr. VP & Chief Medical Officer Jun 06, 2018 Option Exercise $3.20 5,000 16,000 15,125 Jun 07, 2018, 04:06 PM
Conner Edward R. Sr. VP & Chief Medical Officer Jun 06, 2018 Sale $16.67 5,000 83,350 10,125 Jun 07, 2018, 04:06 PM
Yi Kathy SVP & Chief Financial Officer May 15, 2018 Option Exercise $4.55 5,000 22,750 12,250 May 16, 2018, 06:38 PM
Yi Kathy SVP & Chief Financial Officer May 15, 2018 Sale $15.38 5,000 76,920 7,250 May 16, 2018, 06:38 PM
Conner Edward R. Sr. VP & Chief Medical Officer May 07, 2018 Option Exercise $3.20 5,000 16,000 15,125 May 09, 2018, 05:38 PM
Conner Edward R. Sr. VP & Chief Medical Officer May 07, 2018 Sale $16.36 5,000 81,814 10,125 May 09, 2018, 05:38 PM
Yi Kathy SVP & Chief Financial Officer Apr 16, 2018 Option Exercise $4.55 5,000 22,750 12,250 Apr 18, 2018, 04:04 PM
Yi Kathy SVP & Chief Financial Officer Apr 16, 2018 Sale $19.83 5,000 99,144 7,250 Apr 18, 2018, 04:04 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Apr 13, 2018 Option Exercise $14.07 8,163 114,853 22,788 Apr 17, 2018, 04:16 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Apr 13, 2018 Sale $20.00 8,163 163,260 14,625 Apr 17, 2018, 04:16 PM
Conner Edward R. Sr. VP & Chief Medical Officer Apr 06, 2018 Option Exercise $3.20 5,000 16,000 13,125 Apr 09, 2018, 06:43 PM
Conner Edward R. Sr. VP & Chief Medical Officer Apr 06, 2018 Sale $17.41 5,000 87,065 8,125 Apr 09, 2018, 06:43 PM
Mento Steven J Director Apr 02, 2018 Option Exercise $7.77 10,000 77,700 19,047 Apr 04, 2018, 04:10 PM
Mento Steven J Director Apr 02, 2018 Sale $18.40 7,215 132,758 11,932 Apr 04, 2018, 04:10 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Apr 02, 2018 Option Exercise $5.35 2,278 12,199 16,903 Apr 04, 2018, 04:09 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Apr 02, 2018 Sale $18.30 2,278 41,684 14,625 Apr 04, 2018, 04:09 PM
Yi Kathy SVP & Chief Financial Officer Mar 15, 2018 Option Exercise $4.55 5,000 22,750 12,250 Mar 16, 2018, 07:41 PM
Yi Kathy SVP & Chief Financial Officer Mar 15, 2018 Sale $25.56 5,000 127,812 7,250 Mar 16, 2018, 07:41 PM
Conner Edward R. Sr. VP & Chief Medical Officer Mar 06, 2018 Option Exercise $3.20 5,000 16,000 13,125 Mar 07, 2018, 08:43 PM
Conner Edward R. Sr. VP & Chief Medical Officer Mar 06, 2018 Sale $24.78 5,000 123,877 8,125 Mar 07, 2018, 08:43 PM
Mento Steven J Director Mar 01, 2018 Option Exercise $5.49 15,000 82,350 18,480 Mar 05, 2018, 06:50 PM
Mento Steven J Director Mar 01, 2018 Sale $23.27 9,433 219,546 9,047 Mar 05, 2018, 06:50 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Mar 01, 2018 Option Exercise $9.86 15,000 147,905 29,625 Mar 05, 2018, 06:39 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Mar 01, 2018 Sale $23.06 15,000 345,861 14,625 Mar 05, 2018, 06:39 PM
Ramasastry Saira Director Feb 26, 2018 Option Exercise $5.03 9,450 47,534 9,450 Feb 27, 2018, 06:41 PM
Ramasastry Saira Director Feb 26, 2018 Sale $24.88 9,450 235,080 0 Feb 27, 2018, 06:41 PM
Conner Edward R. Sr. VP & Chief Medical Officer Feb 06, 2018 Option Exercise $3.20 5,000 16,000 13,125 Feb 07, 2018, 05:17 PM
Conner Edward R. Sr. VP & Chief Medical Officer Feb 06, 2018 Sale $18.49 5,000 92,436 8,125 Feb 07, 2018, 05:17 PM
Mento Steven J Director Feb 01, 2018 Option Exercise $8.92 15,000 133,750 15,000 Feb 05, 2018, 08:05 PM
Mento Steven J Director Feb 01, 2018 Sale $20.59 11,520 237,159 3,480 Feb 05, 2018, 08:05 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Feb 01, 2018 Option Exercise $3.50 15,000 52,500 29,625 Feb 05, 2018, 08:04 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Feb 01, 2018 Sale $20.59 15,000 308,854 14,625 Feb 05, 2018, 08:04 PM
Conner Edward R. Sr. VP & Chief Medical Officer Jan 08, 2018 Option Exercise $3.20 5,000 16,000 7,000 Jan 10, 2018, 05:51 PM
Conner Edward R. Sr. VP & Chief Medical Officer Jan 08, 2018 Sale $17.11 5,000 85,545 2,000 Jan 10, 2018, 05:51 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Jan 03, 2018 Option Exercise $12.12 8,026 97,275 14,276 Jan 04, 2018, 07:34 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Jan 02, 2018 Option Exercise $9.30 991 9,212 13,224 Jan 04, 2018, 07:34 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Jan 03, 2018 Sale $18.05 8,026 144,869 6,250 Jan 04, 2018, 07:34 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Jan 02, 2018 Sale $16.35 6,974 114,025 6,250 Jan 04, 2018, 07:34 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Dec 08, 2017 Option Exercise $16.90 2,348 39,681 13,485 Dec 12, 2017, 06:08 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Dec 11, 2017 Option Exercise $15.85 1,252 19,844 12,233 Dec 12, 2017, 06:08 PM
Conner Edward R. Sr. VP & Chief Medical Officer Dec 06, 2017 Option Exercise $3.20 5,000 16,000 5,000 Dec 08, 2017, 06:53 PM
Conner Edward R. Sr. VP & Chief Medical Officer Dec 06, 2017 Sale $16.24 5,000 81,200 0 Dec 08, 2017, 06:53 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Dec 04, 2017 Option Exercise $12.12 11,803 143,052 27,636 Dec 06, 2017, 07:17 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Dec 04, 2017 Sale $18.00 11,803 212,454 15,833 Dec 06, 2017, 07:17 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Dec 01, 2017 Option Exercise $9.22 1,197 11,039 19,030 Dec 04, 2017, 08:06 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Nov 30, 2017 Option Exercise $9.41 13,433 126,405 31,266 Dec 04, 2017, 08:06 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Nov 30, 2017 Sale $16.00 13,433 214,928 17,833 Dec 04, 2017, 08:06 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Dec 01, 2017 Sale $16.70 3,197 53,390 15,833 Dec 04, 2017, 08:06 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Nov 30, 2017 Option Exercise $9.41 13,433 126,405 31,266 Dec 04, 2017, 07:39 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Dec 01, 2017 Option Exercise $9.22 1,197 11,039 19,030 Dec 04, 2017, 07:39 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Nov 30, 2017 Sale $16.00 13,433 214,928 17,833 Dec 04, 2017, 07:39 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Dec 01, 2017 Sale $16.70 3,197 53,390 15,833 Dec 04, 2017, 07:39 PM
Ramasastry Saira Director Nov 17, 2017 Option Exercise $5.03 5,000 25,150 5,000 Nov 21, 2017, 05:01 PM
Ramasastry Saira Director Nov 17, 2017 Sale $14.67 5,000 73,339 0 Nov 21, 2017, 05:01 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Oct 02, 2017 Option Exercise $7.66 15,000 114,905 21,663 Oct 04, 2017, 04:22 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Oct 02, 2017 Sale $15.25 15,000 228,754 15,833 Oct 04, 2017, 04:22 PM
RINGO WILLIAM R Director Sep 20, 2017 Option Exercise $6.05 31,000 187,550 31,800 Sep 22, 2017, 04:04 PM
RINGO WILLIAM R Director Sep 20, 2017 Sale $14.37 31,000 445,597 800 Sep 22, 2017, 04:04 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Sep 01, 2017 Option Exercise $5.41 10,316 55,810 26,149 Sep 01, 2017, 06:19 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Sep 01, 2017 Sale $15.00 15,000 225,000 15,833 Sep 01, 2017, 06:19 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Aug 14, 2017 Option Exercise $5.12 5,000 25,600 25,517 Aug 15, 2017, 05:31 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Aug 11, 2017 Option Exercise $3.32 6,474 21,511 26,991 Aug 15, 2017, 05:31 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Aug 11, 2017 Sale $10.00 6,474 64,740 20,517 Aug 15, 2017, 05:31 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Aug 14, 2017 Sale $11.00 5,000 55,000 20,517 Aug 15, 2017, 05:31 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Jul 14, 2017 Option Exercise $3.99 172 686 35,517 Jul 14, 2017, 08:06 PM
Herberts Curt A. III Sr.VP & Chief Business Officer Jul 14, 2017 Sale $10.00 15,000 150,000 35,345 Jul 14, 2017, 08:06 PM
Herberts Curt A. III Senior VP & CBO Jun 01, 2017 Sale $6.80 2,000 13,600 35,345 Jun 02, 2017, 08:26 PM
Herberts Curt A. III Senior VP & CBO May 12, 2017 Sale $8.50 2,000 17,000 37,345 May 15, 2017, 07:42 PM
Herberts Curt A. III Senior VP & CBO May 11, 2017 Sale $6.50 639 4,154 39,345 May 15, 2017, 07:42 PM
Herberts Curt A. III Senior VP & CBO Dec 12, 2016 Option Exercise $3.05 4,852 14,799 33,300 Dec 14, 2016, 08:11 PM
Wolff Henry Ward Exec VP & CFO Dec 12, 2015 Option Exercise $3.05 13,778 42,023 206,829 Dec 14, 2016, 08:03 PM
LANPHIER EDWARD O II Director Jun 13, 2016 Option Exercise $6.23 84,642 527,320 223,938 Jun 15, 2016, 08:22 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 11, 2015 Option Exercise $8.68 4,348 37,741 111,328 Dec 15, 2015, 05:12 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 12, 2015 Option Exercise $8.68 4,000 34,720 107,328 Dec 15, 2015, 05:12 PM
LANPHIER EDWARD O II President & CEO Dec 12, 2015 Option Exercise $8.68 13,045 113,231 293,906 Dec 15, 2015, 05:11 PM
LANPHIER EDWARD O II President & CEO Dec 11, 2015 Option Exercise $8.68 21,741 188,712 306,951 Dec 15, 2015, 05:11 PM
NICHOL GEOFFREY Executive Vice President, R&D Dec 12, 2015 Option Exercise $8.68 4,384 38,053 159,676 Dec 15, 2015, 05:11 PM
NICHOL GEOFFREY Executive Vice President, R&D Dec 11, 2015 Option Exercise $8.68 4,697 40,770 164,060 Dec 15, 2015, 05:11 PM
Wolff Henry Ward Exec VP & CFO Dec 11, 2015 Option Exercise $8.68 6,522 56,611 221,790 Dec 15, 2015, 05:09 PM
Wolff Henry Ward Exec VP & CFO Dec 12, 2015 Option Exercise $8.68 6,087 52,835 215,703 Dec 15, 2015, 05:09 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 07, 2015 Option Exercise $9.69 6,087 58,983 115,676 Dec 09, 2015, 04:53 PM
LANPHIER EDWARD O II President & CEO Dec 07, 2015 Option Exercise $9.69 31,308 303,375 328,692 Dec 09, 2015, 04:51 PM
NICHOL GEOFFREY Executive Vice President, R&D Dec 07, 2015 Option Exercise $9.69 6,889 66,754 168,757 Dec 09, 2015, 04:50 PM
Wolff Henry Ward Exec VP & CFO Dec 07, 2015 Option Exercise $9.69 7,060 68,411 228,312 Dec 09, 2015, 04:47 PM
LANPHIER EDWARD O II President & CEO Jul 15, 2015 Option Exercise $6.82 25,000 170,500 260,000 Jul 17, 2015, 04:49 PM
LANPHIER EDWARD O II President & CEO Jul 15, 2015 Sale $10.43 25,000 260,770 235,000 Jul 17, 2015, 04:49 PM
Wolff Henry Ward Exec VP & CFO Jul 10, 2015 Option Exercise $3.45 6,102 21,052 205,974 Jul 14, 2015, 04:46 PM
Wolff Henry Ward Exec VP & CFO Jul 13, 2015 Option Exercise $3.45 3,898 13,448 203,770 Jul 14, 2015, 04:46 PM
Wolff Henry Ward Exec VP & CFO Jul 13, 2015 Sale $10.00 5,898 58,980 199,872 Jul 14, 2015, 04:46 PM
Wolff Henry Ward Exec VP & CFO Jul 10, 2015 Sale $10.00 6,102 61,020 199,872 Jul 14, 2015, 04:46 PM
LANPHIER EDWARD O II President & CEO Jun 15, 2015 Option Exercise $6.82 25,000 170,500 260,000 Jun 17, 2015, 04:47 PM
LANPHIER EDWARD O II President & CEO Jun 15, 2015 Sale $11.08 25,000 277,078 235,000 Jun 17, 2015, 04:47 PM
Wolff Henry Ward Exec VP & CFO Jun 10, 2015 Option Exercise $3.45 10,000 34,500 211,872 Jun 12, 2015, 04:50 PM
Wolff Henry Ward Exec VP & CFO Jun 10, 2015 Sale $12.21 12,000 146,558 201,872 Jun 12, 2015, 04:50 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jun 05, 2015 Option Exercise $3.45 15,000 51,750 111,763 Jun 09, 2015, 05:26 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jun 05, 2015 Sale $12.29 15,000 184,394 96,763 Jun 09, 2015, 05:26 PM
RINGO WILLIAM R Director Jun 03, 2015 Option Exercise $6.05 2,200 13,310 3,000 Jun 03, 2015, 09:07 PM
RINGO WILLIAM R Director Jun 03, 2015 Sale $12.44 2,200 27,364 800 Jun 03, 2015, 09:07 PM
Gregory Philip D SVP of Research & CSO Jun 01, 2015 Option Exercise $5.13 15,000 77,000 131,410 Jun 03, 2015, 09:06 PM
Gregory Philip D SVP of Research & CSO Jun 01, 2015 Sale $12.39 15,000 185,816 116,410 Jun 03, 2015, 09:06 PM
LANPHIER EDWARD O II President & CEO May 15, 2015 Option Exercise $6.82 25,000 170,500 260,000 May 19, 2015, 05:26 PM
LANPHIER EDWARD O II President & CEO May 15, 2015 Sale $11.51 25,000 287,862 235,000 May 19, 2015, 05:26 PM
Wolff Henry Ward Exec VP & CFO May 11, 2015 Option Exercise $3.45 10,000 34,500 213,872 May 13, 2015, 04:40 PM
Wolff Henry Ward Exec VP & CFO May 11, 2015 Sale $13.25 12,000 158,949 203,872 May 13, 2015, 04:40 PM
ANDO DALE G VP, Therapeutic Dev. & CMO May 05, 2015 Option Exercise $3.45 15,000 51,750 110,376 May 05, 2015, 07:26 PM
ANDO DALE G VP, Therapeutic Dev. & CMO May 05, 2015 Sale $12.29 15,000 184,297 95,376 May 05, 2015, 07:26 PM
RINGO WILLIAM R Director May 04, 2015 Option Exercise $6.19 3,000 18,582 3,800 May 05, 2015, 07:23 PM
RINGO WILLIAM R Director May 04, 2015 Sale $12.98 3,000 38,927 800 May 05, 2015, 07:23 PM
Gregory Philip D SVP of Research & CSO May 01, 2015 Option Exercise $5.13 15,000 77,000 131,410 May 05, 2015, 07:05 PM
Gregory Philip D SVP of Research & CSO May 01, 2015 Sale $12.62 15,000 189,370 116,410 May 05, 2015, 07:05 PM
LANPHIER EDWARD O II President & CEO Apr 15, 2015 Option Exercise $6.82 25,000 170,500 260,000 Apr 17, 2015, 07:03 PM
LANPHIER EDWARD O II President & CEO Apr 15, 2015 Sale $15.33 25,000 383,260 235,000 Apr 17, 2015, 07:03 PM
Wolff Henry Ward Exec VP & CFO Apr 10, 2015 Option Exercise $3.45 10,000 34,500 214,849 Apr 14, 2015, 07:03 PM
Wolff Henry Ward Exec VP & CFO Apr 10, 2015 Sale $15.31 12,000 183,771 204,849 Apr 14, 2015, 07:03 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Apr 06, 2015 Option Exercise $3.45 15,000 51,750 110,376 Apr 08, 2015, 07:06 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Apr 06, 2015 Sale $14.94 15,000 224,172 95,376 Apr 08, 2015, 07:06 PM
RINGO WILLIAM R Director Apr 06, 2015 Option Exercise $6.41 2,200 14,102 3,000 Apr 08, 2015, 07:05 PM
RINGO WILLIAM R Director Apr 06, 2015 Sale $14.95 2,200 32,881 800 Apr 08, 2015, 07:05 PM
Gregory Philip D SVP of Research & CSO Apr 01, 2015 Option Exercise $5.13 15,000 77,000 131,410 Apr 03, 2015, 07:53 PM
Gregory Philip D SVP of Research & CSO Apr 01, 2015 Sale $15.15 15,000 227,192 116,410 Apr 03, 2015, 07:53 PM
Wolff Henry Ward Exec VP & CFO Mar 19, 2015 Option Exercise $14.27 10,000 142,700 214,849 Mar 20, 2015, 07:28 PM
Wolff Henry Ward Exec VP & CFO Mar 19, 2015 Sale $18.00 10,000 180,000 204,849 Mar 20, 2015, 07:28 PM
LANPHIER EDWARD O II President & CEO Mar 16, 2015 Option Exercise $6.82 25,000 170,500 260,000 Mar 18, 2015, 08:02 PM
LANPHIER EDWARD O II President & CEO Mar 16, 2015 Sale $17.29 25,000 432,305 235,000 Mar 18, 2015, 08:02 PM
Wolff Henry Ward Exec VP & CFO Mar 10, 2015 Option Exercise $3.45 10,000 34,500 216,849 Mar 12, 2015, 08:09 PM
Wolff Henry Ward Exec VP & CFO Mar 10, 2015 Sale $16.68 12,000 200,201 206,849 Mar 12, 2015, 08:09 PM
Wolff Henry Ward Exec VP & CFO Mar 04, 2015 Option Exercise $14.27 10,000 142,700 216,849 Mar 06, 2015, 07:04 PM
Wolff Henry Ward Exec VP & CFO Mar 04, 2015 Sale $18.00 10,000 180,000 206,849 Mar 06, 2015, 07:04 PM
Mento Steven J Director Mar 05, 2015 Option Exercise $4.54 10,000 45,400 18,771 Mar 06, 2015, 06:51 PM
Mento Steven J Director Mar 05, 2015 Sale $18.30 6,501 118,939 12,270 Mar 06, 2015, 06:51 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Mar 05, 2015 Option Exercise $3.45 15,000 51,750 110,376 Mar 06, 2015, 06:49 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Mar 05, 2015 Sale $18.29 15,000 274,282 95,376 Mar 06, 2015, 06:49 PM
RINGO WILLIAM R Director Mar 03, 2015 Option Exercise $6.41 2,200 14,102 3,000 Mar 04, 2015, 08:06 PM
RINGO WILLIAM R Director Mar 03, 2015 Sale $17.21 2,200 37,862 800 Mar 04, 2015, 08:06 PM
Gregory Philip D SVP of Research & CSO Mar 02, 2015 Option Exercise $7.34 15,000 110,120 131,410 Mar 04, 2015, 08:04 PM
Gregory Philip D SVP of Research & CSO Mar 02, 2015 Sale $17.26 15,000 258,938 116,410 Mar 04, 2015, 08:04 PM
LANPHIER EDWARD O II President & CEO Feb 17, 2015 Option Exercise $6.82 25,000 170,500 260,000 Feb 19, 2015, 08:05 PM
LANPHIER EDWARD O II President & CEO Feb 17, 2015 Sale $15.69 25,000 392,150 235,000 Feb 19, 2015, 08:05 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 17, 2014 Buy $12.26 37,215 456,211 2,199,753 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 30, 2014 Sale $12.42 109,590 1,361,606 1,946,194 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 01, 2014 Sale $16.01 82,700 1,323,999 2,212,158 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 29, 2014 Sale $12.41 1,407 17,464 1,966,786 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jun 16, 2014 Sale $16.55 250,500 4,146,531 2,493,900 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 28, 2014 Sale $12.11 60,081 727,474 2,003,464 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jun 09, 2014 Sale $15.50 83,500 1,294,159 2,518,283 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 25, 2014 Sale $12.31 47,429 583,951 2,028,274 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jun 06, 2014 Sale $14.29 135,101 1,930,949 2,704,487 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 24, 2014 Sale $12.28 124,050 1,523,235 2,075,703 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Aug 01, 2014 Sale $12.82 27,770 356,100 1,829,426 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jun 05, 2014 Sale $14.13 115,102 1,626,669 2,763,188 Feb 18, 2015, 09:54 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 07, 2014 Buy $12.09 35,736 431,870 4,857,972 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 28, 2014 Sale $13.43 148,689 1,996,952 4,193,136 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jun 05, 2014 Sale $13.06 970,361 12,669,888 2,881,303 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 08, 2014 Sale $12.40 83,300 1,032,587 4,837,147 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 27, 2014 Sale $13.55 263,437 3,570,473 4,426,386 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jun 04, 2014 Sale $13.10 70,640 925,227 3,849,783 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 23, 2014 Sale $13.27 51,597 684,713 4,580,960 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jun 03, 2014 Sale $12.86 76,833 988,072 3,870,442 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 22, 2014 Sale $13.56 56,396 764,537 4,673,375 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 30, 2014 Sale $13.40 65,884 883,147 3,971,508 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 13, 2014 Sale $13.12 56,060 735,305 4,688,953 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 29, 2014 Sale $13.53 155,675 2,106,559 4,159,444 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 12, 2014 Sale $13.03 29,659 386,330 4,755,283 Feb 18, 2015, 09:53 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 25, 2014 Buy $13.63 166,000 2,262,779 4,575,328 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 07, 2014 Buy $15.42 33,667 519,310 4,475,024 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 11, 2014 Buy $14.48 116,992 1,694,299 4,723,633 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 04, 2014 Buy $15.38 179,031 2,753,712 4,441,357 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 17, 2014 Buy $14.02 41,500 581,959 4,762,078 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner May 07, 2014 Buy $11.73 47,564 557,989 4,822,236 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 03, 2014 Buy $16.61 195,126 3,241,999 4,262,326 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 10, 2014 Buy $14.91 83,000 1,237,339 4,610,044 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 30, 2014 Buy $13.45 124,500 1,674,679 4,774,672 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 15, 2014 Buy $13.16 21,829 287,206 4,742,407 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 28, 2014 Buy $13.29 74,844 995,014 4,650,172 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 08, 2014 Buy $15.49 121,876 1,888,274 4,596,900 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 14, 2014 Sale $14.78 3,055 45,165 4,720,578 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 22, 2014 Sale $14.86 352,750 5,243,538 4,722,487 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 10, 2014 Sale $15.67 3,403 53,326 4,606,641 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 16, 2014 Sale $14.09 21,829 307,658 4,720,578 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 09, 2014 Sale $16.27 69,856 1,136,424 4,527,044 Feb 18, 2015, 09:52 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 27, 2014 Buy $17.65 256,187 4,522,356 4,233,200 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 17, 2014 Buy $23.02 52,161 1,200,835 3,683,000 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 26, 2014 Buy $18.14 210,013 3,808,711 3,977,013 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 13, 2014 Buy $22.76 71,319 1,623,356 3,683,000 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 25, 2014 Buy $19.42 84,000 1,631,041 3,767,000 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 21, 2014 Buy $21.22 101,808 2,159,989 3,683,000 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 10, 2014 Buy $22.30 12,522 279,180 3,683,000 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 28, 2014 Buy $17.10 84,000 1,436,056 4,317,200 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 07, 2014 Buy $22.25 258,377 5,748,552 3,683,000 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 18, 2014 Sale $23.74 84,000 1,994,573 3,683,000 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 06, 2014 Sale $24.10 61,483 1,481,538 3,683,000 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 12, 2014 Sale $23.40 123,480 2,889,432 3,683,000 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Apr 01, 2014 Sale $18.01 250,000 4,502,381 4,268,700 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 19, 2014 Sale $24.28 17,808 432,432 3,683,000 Feb 18, 2015, 09:51 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 05, 2014 Buy $18.23 42,000 765,828 3,725,002 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 26, 2014 Buy $19.57 74,194 1,452,243 3,757,196 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 12, 2014 Buy $18.04 42,000 757,621 3,767,002 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 06, 2014 Buy $22.50 84,001 1,890,245 3,683,000 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 11, 2014 Buy $19.65 42,000 825,275 3,725,002 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 28, 2014 Buy $18.10 42,000 760,145 3,767,000 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 14, 2014 Sale $18.61 15,380 286,166 3,736,213 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 27, 2014 Sale $19.37 32,196 623,499 3,742,243 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 13, 2014 Sale $18.46 15,409 284,438 3,751,593 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 06, 2014 Sale $23.28 293,417 6,831,412 3,683,000 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 20, 2014 Sale $18.40 35,319 649,869 3,718,282 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 19, 2014 Sale $18.51 6,720 124,420 3,718,321 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Mar 03, 2014 Sale $18.21 84,000 1,529,902 3,699,800 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 07, 2014 Sale $18.52 34,688 642,432 3,683,002 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 18, 2014 Sale $18.11 11,172 202,278 3,725,041 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Feb 06, 2014 Sale $18.42 7,312 134,683 3,717,690 Feb 18, 2015, 09:49 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner. Dec 13, 2013 Buy $12.09 5,040 60,921 4,043,002 Feb 18, 2015, 06:38 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner. Dec 12, 2013 Buy $12.09 9,600 116,071 4,037,962 Feb 18, 2015, 06:38 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner. Jan 09, 2014 Sale $18.35 72,440 1,329,365 4,015,519 Feb 18, 2015, 06:38 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 17, 2013 Buy $9.79 19,200 187,895 3,645,703 Feb 18, 2015, 06:37 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 23, 2013 Sale $9.37 5,012 46,938 3,487,088 Feb 18, 2015, 06:37 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 22, 2013 Sale $9.57 111,363 1,065,610 3,526,662 Feb 18, 2015, 06:37 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 19, 2013 Sale $9.84 209,894 2,065,714 3,603,463 Feb 18, 2015, 06:37 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 18, 2013 Sale $10.02 74,035 741,498 3,626,503 Feb 18, 2015, 06:37 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 17, 2013 Sale $10.22 48,270 493,401 3,626,503 Feb 18, 2015, 06:37 PM
RA CAPITAL MANAGEMENT, LLC Former 10% Owner Jul 25, 2013 Sale $9.71 368,870 3,582,848 3,483,017 Feb 18, 2015, 06:37 PM
Ramasastry Saira Director Feb 12, 2015 Option Exercise $5.03 10,000 50,300 10,000 Feb 13, 2015, 07:45 PM
Ramasastry Saira Director Feb 12, 2015 Sale $15.00 10,000 150,000 0 Feb 13, 2015, 07:45 PM
Wolff Henry Ward Exec VP & CFO Feb 10, 2015 Option Exercise $3.45 10,000 34,500 218,849 Feb 12, 2015, 08:14 PM
Wolff Henry Ward Exec VP & CFO Feb 10, 2015 Sale $12.65 12,000 151,750 208,849 Feb 12, 2015, 08:14 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Feb 05, 2015 Option Exercise $6.10 15,000 91,509 110,376 Feb 06, 2015, 07:50 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Feb 05, 2015 Sale $12.93 15,000 193,950 95,376 Feb 06, 2015, 07:50 PM
RINGO WILLIAM R Director Feb 03, 2015 Option Exercise $6.41 2,200 14,102 3,000 Feb 05, 2015, 08:19 PM
RINGO WILLIAM R Director Feb 03, 2015 Sale $12.70 2,200 27,940 800 Feb 05, 2015, 08:19 PM
Gregory Philip D SVP of Research & CSO Feb 02, 2015 Option Exercise $5.13 15,000 77,000 131,410 Feb 04, 2015, 07:31 PM
Gregory Philip D SVP of Research & CSO Feb 02, 2015 Sale $12.86 15,000 192,829 116,410 Feb 04, 2015, 07:31 PM
LANPHIER EDWARD O II President & CEO Jan 16, 2015 Option Exercise $6.82 10,000 68,200 245,000 Jan 16, 2015, 08:20 PM
LANPHIER EDWARD O II President & CEO Jan 15, 2015 Option Exercise $6.82 15,000 102,300 250,000 Jan 16, 2015, 08:20 PM
LANPHIER EDWARD O II President & CEO Jan 16, 2015 Sale $14.29 10,000 142,853 235,000 Jan 16, 2015, 08:20 PM
LANPHIER EDWARD O II President & CEO Jan 15, 2015 Sale $14.18 15,000 212,769 236,600 Jan 16, 2015, 08:20 PM
Wolff Henry Ward Exec VP & CFO Jan 12, 2015 Option Exercise $3.45 10,000 34,500 220,849 Jan 14, 2015, 07:02 PM
Wolff Henry Ward Exec VP & CFO Jan 12, 2015 Sale $15.87 12,000 190,450 210,849 Jan 14, 2015, 07:02 PM
RINGO WILLIAM R Director Jan 05, 2015 Option Exercise $6.41 2,200 14,102 3,000 Jan 06, 2015, 07:27 PM
RINGO WILLIAM R Director Jan 05, 2015 Sale $15.20 2,200 33,430 800 Jan 06, 2015, 07:27 PM
LARSON JOHN WILLIAM Director Jan 05, 2015 Option Exercise $6.86 15,000 102,850 229,660 Jan 06, 2015, 07:26 PM
LARSON JOHN WILLIAM Director Jan 05, 2015 Sale $15.10 15,000 226,550 214,660 Jan 06, 2015, 07:26 PM
Gregory Philip D SVP, Research & CSO Jan 02, 2015 Option Exercise $7.34 15,000 110,120 131,410 Jan 06, 2015, 07:25 PM
Gregory Philip D SVP, Research & CSO Jan 02, 2015 Sale $15.78 15,000 236,664 116,410 Jan 06, 2015, 07:25 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jan 05, 2015 Option Exercise $6.82 15,000 102,300 110,376 Jan 06, 2015, 07:24 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jan 05, 2015 Sale $15.19 15,000 227,854 95,976 Jan 06, 2015, 07:24 PM
Wolff Henry Ward Exec VP & CFO Dec 15, 2014 Option Exercise $14.74 40,004 589,587 210,849 Dec 17, 2014, 08:00 PM
NICHOL GEOFFREY Executive Vice President, R&D Dec 15, 2014 Option Exercise $14.74 41,743 615,217 138,146 Dec 15, 2014, 09:51 PM
LANPHIER EDWARD O II President & CEO Dec 15, 2014 Option Exercise $14.74 96,533 1,422,723 323,467 Dec 15, 2014, 09:49 PM
LANPHIER EDWARD O II President & CEO Dec 15, 2014 Option Exercise $4.11 25,000 102,750 348,467 Dec 15, 2014, 09:49 PM
LANPHIER EDWARD O II President & CEO Dec 15, 2014 Sale $15.40 25,000 384,912 339,467 Dec 15, 2014, 09:49 PM
LARSON JOHN WILLIAM Director Dec 15, 2014 Option Exercise $5.95 15,000 89,250 229,660 Dec 15, 2014, 09:23 PM
LARSON JOHN WILLIAM Director Dec 15, 2014 Sale $16.28 10,000 162,829 214,660 Dec 15, 2014, 09:23 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 15, 2014 Option Exercise $14.74 27,480 405,006 95,376 Dec 15, 2014, 09:23 PM
Gregory Philip D Vice President, Research & CSO Dec 15, 2014 Option Exercise $14.74 30,437 448,587 116,410 Dec 15, 2014, 09:22 PM
Wolff Henry Ward Exec VP & CFO Dec 15, 2014 Option Exercise $14.74 40,004 589,587 210,849 Dec 15, 2014, 09:20 PM
Mento Steven J Director Dec 11, 2014 Option Exercise $4.10 10,000 41,000 35,069 Dec 15, 2014, 08:00 PM
Mento Steven J Director Dec 11, 2014 Sale $15.00 6,354 95,310 28,715 Dec 15, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 05, 2014 Option Exercise $6.82 15,000 102,300 112,856 Dec 09, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 05, 2014 Sale $11.21 15,000 168,197 97,856 Dec 09, 2014, 08:00 PM
LARSON JOHN WILLIAM Director Dec 09, 2014 Option Exercise $4.54 10,000 45,400 224,660 Dec 09, 2014, 08:00 PM
LARSON JOHN WILLIAM Director Dec 09, 2014 Sale $12.00 10,000 120,000 214,660 Dec 09, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Dec 01, 2014 Option Exercise $5.13 15,000 77,000 124,347 Dec 03, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Dec 01, 2014 Sale $11.68 15,000 175,191 109,347 Dec 03, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Nov 17, 2014 Option Exercise $4.11 25,000 102,750 320,000 Nov 19, 2014, 08:01 PM
LANPHIER EDWARD O II President & CEO Nov 17, 2014 Sale $11.23 25,000 280,842 295,000 Nov 19, 2014, 08:01 PM
Wolff Henry Ward Exec VP & CFO Nov 10, 2014 Sale $11.37 2,000 22,748 213,353 Nov 13, 2014, 08:00 PM
LARSON JOHN WILLIAM Director Nov 12, 2014 Option Exercise $4.10 10,000 41,000 224,660 Nov 13, 2014, 08:00 PM
LARSON JOHN WILLIAM Director Nov 12, 2014 Sale $12.00 10,000 120,007 214,660 Nov 13, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Nov 05, 2014 Option Exercise $5.59 15,000 83,877 112,856 Nov 07, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Nov 05, 2014 Sale $11.35 15,000 170,258 97,856 Nov 07, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Nov 03, 2014 Option Exercise $5.28 15,000 79,240 124,347 Nov 05, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Nov 03, 2014 Sale $11.91 15,000 178,704 109,347 Nov 05, 2014, 08:00 PM
LARSON JOHN WILLIAM Director Oct 28, 2014 Option Exercise $7.28 10,000 72,800 224,660 Oct 30, 2014, 08:00 PM
LARSON JOHN WILLIAM Director Oct 28, 2014 Sale $12.02 10,000 120,153 214,660 Oct 30, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Oct 15, 2014 Option Exercise $4.11 25,000 102,750 320,000 Oct 17, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Oct 15, 2014 Sale $10.49 25,000 262,365 295,000 Oct 17, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Oct 10, 2014 Sale $10.10 2,000 20,200 214,347 Oct 14, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Oct 06, 2014 Option Exercise $4.11 15,000 61,650 111,579 Oct 08, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Oct 06, 2014 Sale $10.72 15,000 160,865 96,579 Oct 08, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Oct 01, 2014 Option Exercise $5.66 15,000 84,840 124,347 Oct 03, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Oct 01, 2014 Sale $10.80 15,000 162,028 109,347 Oct 03, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Sep 15, 2014 Option Exercise $4.11 25,000 102,750 320,000 Sep 17, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Sep 15, 2014 Sale $12.14 25,000 303,382 295,000 Sep 17, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Sep 10, 2014 Sale $12.31 2,000 24,620 216,347 Sep 12, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Sep 05, 2014 Option Exercise $4.11 15,000 61,650 111,579 Sep 05, 2014, 09:45 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Sep 05, 2014 Sale $12.20 15,000 183,072 96,579 Sep 05, 2014, 09:45 PM
LARSON JOHN WILLIAM Director Sep 04, 2014 Option Exercise $7.73 10,000 77,300 228,160 Sep 05, 2014, 05:00 PM
LARSON JOHN WILLIAM Director Sep 04, 2014 Sale $12.81 10,000 128,082 218,160 Sep 05, 2014, 05:00 PM
Gregory Philip D SVP of Research & CSO Sep 02, 2014 Option Exercise $5.66 15,000 84,840 124,347 Sep 04, 2014, 05:00 PM
Gregory Philip D SVP of Research & CSO Sep 02, 2014 Sale $13.45 15,000 201,798 109,347 Sep 04, 2014, 05:00 PM
LANPHIER EDWARD O II President & CEO Aug 15, 2014 Option Exercise $4.11 25,000 102,750 320,000 Aug 15, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Aug 15, 2014 Sale $13.95 25,000 348,797 295,000 Aug 15, 2014, 08:00 PM
Ramasastry Saira Director Aug 08, 2014 Option Exercise $5.03 10,000 50,300 10,000 Aug 12, 2014, 08:00 PM
Ramasastry Saira Director Aug 08, 2014 Sale $14.00 10,000 140,000 0 Aug 12, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Aug 11, 2014 Option Exercise $7.28 8,000 58,240 228,347 Aug 12, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Aug 11, 2014 Sale $14.17 10,000 141,677 220,347 Aug 12, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Aug 05, 2014 Option Exercise $4.11 13,202 54,260 111,579 Aug 05, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Aug 05, 2014 Sale $12.99 15,000 194,846 98,377 Aug 05, 2014, 08:00 PM
LARSON JOHN WILLIAM Director Aug 04, 2014 Option Exercise $4.00 10,000 40,000 228,160 Aug 05, 2014, 08:00 PM
LARSON JOHN WILLIAM Director Aug 04, 2014 Sale $12.56 10,000 125,578 218,160 Aug 05, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Aug 01, 2014 Option Exercise $5.66 15,000 84,840 124,347 Aug 05, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Aug 01, 2014 Sale $12.54 15,000 188,149 109,347 Aug 05, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Jul 18, 2014 Option Exercise $4.11 25,000 102,750 320,000 Jul 18, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Jul 18, 2014 Sale $12.16 25,000 303,940 295,000 Jul 18, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Jul 10, 2014 Option Exercise $7.66 13,000 99,590 235,347 Jul 11, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Jul 10, 2014 Sale $13.26 15,000 198,902 222,347 Jul 11, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Jul 01, 2014 Option Exercise $5.66 15,000 84,840 124,347 Jul 03, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Jul 01, 2014 Sale $15.66 15,000 234,865 109,347 Jul 03, 2014, 08:00 PM
Ramasastry Saira Director Jun 23, 2014 Option Exercise $5.03 5,550 27,917 5,550 Jun 25, 2014, 08:00 PM
Ramasastry Saira Director Jun 23, 2014 Sale $15.53 5,550 86,217 0 Jun 25, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Jun 16, 2014 Sale $16.41 25,000 410,138 1,516,054 Jun 18, 2014, 08:00 PM
Mento Steven J Director Jun 09, 2014 Option Exercise $7.28 5,834 42,472 29,397 Jun 11, 2014, 08:00 PM
Mento Steven J Director Jun 09, 2014 Sale $15.00 4,328 64,920 25,069 Jun 11, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Jun 10, 2014 Option Exercise $7.73 13,000 100,490 237,347 Jun 11, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Jun 10, 2014 Sale $15.62 15,000 234,328 224,347 Jun 11, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Jun 02, 2014 Option Exercise $5.66 15,000 84,840 124,347 Jun 04, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO Jun 02, 2014 Sale $12.85 15,000 192,723 109,347 Jun 04, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO May 27, 2014 Option Exercise $3.68 15,000 55,230 111,377 May 29, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO May 27, 2014 Sale $13.57 15,000 203,531 98,377 May 29, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO May 15, 2014 Sale $13.14 25,000 328,542 1,541,054 May 16, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO May 12, 2014 Option Exercise $7.73 13,000 100,490 239,347 May 14, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO May 12, 2014 Sale $12.85 15,000 192,756 226,347 May 14, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO May 01, 2014 Option Exercise $5.66 15,000 84,840 124,347 May 02, 2014, 08:00 PM
Gregory Philip D SVP of Research & CSO May 01, 2014 Sale $13.68 15,000 205,179 109,347 May 02, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Apr 28, 2014 Option Exercise $3.68 15,000 55,230 110,015 Apr 30, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Apr 28, 2014 Sale $13.64 15,000 204,532 97,015 Apr 30, 2014, 08:00 PM
LARSON JOHN WILLIAM Director Apr 28, 2014 Option Exercise $5.66 10,000 56,600 228,160 Apr 30, 2014, 08:00 PM
LARSON JOHN WILLIAM Director Apr 28, 2014 Sale $13.48 10,000 134,786 218,160 Apr 30, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Apr 15, 2014 Sale $14.20 25,000 355,012 1,566,054 Apr 17, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Apr 10, 2014 Option Exercise $7.73 13,000 100,490 240,347 Apr 11, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Apr 10, 2014 Sale $15.72 15,000 235,798 227,347 Apr 11, 2014, 08:00 PM
Gregory Philip D Sr. VP Res. & CSO Apr 01, 2014 Option Exercise $7.57 15,000 113,480 124,347 Apr 03, 2014, 08:01 PM
Gregory Philip D Sr. VP Res. & CSO Apr 01, 2014 Sale $17.80 15,000 267,000 109,347 Apr 03, 2014, 08:01 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Mar 26, 2014 Option Exercise $3.68 15,000 55,230 110,015 Mar 28, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Mar 26, 2014 Sale $18.65 15,000 279,695 97,215 Mar 28, 2014, 08:00 PM
Gregory Philip D See Remarks Mar 21, 2014 Option Exercise $7.64 15,000 114,662 124,347 Mar 25, 2014, 08:00 PM
Gregory Philip D See Remarks Mar 21, 2014 Sale $22.38 15,000 335,763 109,347 Mar 25, 2014, 08:00 PM
Ramasastry Saira Director Mar 17, 2014 Option Exercise $5.03 10,000 50,300 10,000 Mar 17, 2014, 08:02 PM
Ramasastry Saira Director Mar 17, 2014 Sale $23.26 10,000 232,608 0 Mar 17, 2014, 08:02 PM
Mento Steven J Director Mar 14, 2014 Option Exercise $3.87 9,722 37,624 29,666 Mar 17, 2014, 08:00 PM
Mento Steven J Director Mar 14, 2014 Sale $22.77 6,103 138,955 23,563 Mar 17, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Mar 17, 2014 Option Exercise $5.19 50,000 259,500 345,000 Mar 17, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Mar 17, 2014 Sale $23.22 50,000 1,160,930 295,000 Mar 17, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Mar 10, 2014 Option Exercise $3.45 10,000 34,500 237,347 Mar 12, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Mar 10, 2014 Sale $22.31 10,000 223,071 227,347 Mar 12, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Feb 26, 2014 Option Exercise $3.68 15,000 55,230 110,015 Feb 28, 2014, 08:01 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Feb 26, 2014 Sale $19.72 15,000 295,752 97,015 Feb 28, 2014, 08:01 PM
LANPHIER EDWARD O II President & CEO Feb 18, 2014 Option Exercise $5.19 50,000 259,500 345,000 Feb 19, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Feb 18, 2014 Sale $18.09 50,000 904,350 295,000 Feb 19, 2014, 08:00 PM
RINGO WILLIAM R Director Feb 14, 2014 Option Exercise $5.64 25,000 141,050 25,800 Feb 19, 2014, 08:00 PM
RINGO WILLIAM R Director Feb 14, 2014 Sale $18.06 25,000 451,575 800 Feb 19, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Feb 10, 2014 Option Exercise $3.45 10,000 34,500 237,347 Feb 12, 2014, 08:02 PM
Wolff Henry Ward Exec VP & CFO Feb 10, 2014 Sale $19.26 10,000 192,638 227,347 Feb 12, 2014, 08:02 PM
Gregory Philip D Vice President, Research & CSO Feb 03, 2014 Option Exercise $3.76 15,000 56,370 124,347 Feb 05, 2014, 08:00 PM
Gregory Philip D Vice President, Research & CSO Feb 03, 2014 Sale $18.83 15,000 282,516 109,347 Feb 05, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jan 27, 2014 Option Exercise $3.68 15,000 55,230 110,015 Jan 29, 2014, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jan 27, 2014 Sale $18.58 15,000 278,729 97,015 Jan 29, 2014, 08:00 PM
LANPHIER EDWARD O II President & CEO Jan 15, 2014 Option Exercise $6.39 50,000 319,500 345,000 Jan 17, 2014, 08:01 PM
LANPHIER EDWARD O II President & CEO Jan 15, 2014 Sale $18.51 50,000 925,675 295,000 Jan 17, 2014, 08:01 PM
Cleveland Paul B Director Jan 15, 2014 Option Exercise $5.03 8,333 41,915 8,333 Jan 17, 2014, 08:00 PM
Cleveland Paul B Director Jan 15, 2014 Sale $18.68 8,333 155,694 0 Jan 17, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Jan 10, 2014 Option Exercise $3.45 10,000 34,500 237,347 Jan 14, 2014, 08:00 PM
Wolff Henry Ward Exec VP & CFO Jan 10, 2014 Sale $18.69 10,000 186,893 227,347 Jan 14, 2014, 08:00 PM
Gregory Philip D Vice President, Research & CSO Jan 02, 2014 Option Exercise $3.76 15,000 56,370 124,347 Jan 03, 2014, 08:38 PM
Gregory Philip D Vice President, Research & CSO Jan 02, 2014 Sale $13.56 15,000 203,340 109,347 Jan 03, 2014, 08:38 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 26, 2013 Option Exercise $3.68 15,000 55,230 110,015 Dec 30, 2013, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 26, 2013 Sale $14.37 15,000 215,477 97,015 Dec 30, 2013, 08:00 PM
LANPHIER EDWARD O II President & CEO Dec 18, 2013 Option Exercise $6.39 50,000 319,500 345,000 Dec 20, 2013, 08:02 PM
LANPHIER EDWARD O II President & CEO Dec 18, 2013 Sale $12.47 50,000 623,705 295,000 Dec 20, 2013, 08:02 PM
Gregory Philip D Vice President, Research & CSO Dec 12, 2013 Option Exercise $12.12 15,653 189,714 109,347 Dec 13, 2013, 08:55 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 12, 2013 Option Exercise $12.12 14,783 179,170 97,015 Dec 13, 2013, 08:03 PM
LANPHIER EDWARD O II President & CEO Dec 12, 2013 Option Exercise $12.12 57,398 695,664 347,602 Dec 13, 2013, 07:59 PM
NICHOL GEOFFREY Executive Vice President, R&D Dec 12, 2013 Option Exercise $12.12 22,611 274,045 142,389 Dec 13, 2013, 07:58 PM
Wolff Henry Ward Exec VP & CFO Dec 12, 2013 Option Exercise $12.12 20,872 252,969 227,347 Dec 13, 2013, 07:58 PM
Wolff Henry Ward Exec VP & CFO Dec 10, 2013 Option Exercise $3.45 10,000 34,500 223,219 Dec 12, 2013, 08:00 PM
Wolff Henry Ward Exec VP & CFO Dec 10, 2013 Sale $11.97 10,000 119,670 213,219 Dec 12, 2013, 08:00 PM
Gregory Philip D Vice President, Research & CSO Dec 02, 2013 Option Exercise $3.76 15,000 56,370 105,000 Dec 04, 2013, 08:01 PM
Gregory Philip D Vice President, Research & CSO Dec 02, 2013 Sale $11.66 15,000 174,835 90,000 Dec 04, 2013, 08:01 PM
Cleveland Paul B Director Dec 02, 2013 Option Exercise $6.41 10,000 64,100 10,000 Dec 04, 2013, 08:00 PM
Cleveland Paul B Director Dec 02, 2013 Sale $11.64 10,000 116,393 0 Dec 04, 2013, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Nov 26, 2013 Option Exercise $3.90 15,000 58,570 100,798 Nov 29, 2013, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Nov 26, 2013 Sale $11.83 15,000 177,378 88,798 Nov 29, 2013, 08:00 PM
Wolff Henry Ward Exec VP & CFO Nov 13, 2013 Option Exercise $3.45 10,000 34,500 223,219 Nov 15, 2013, 08:01 PM
Wolff Henry Ward Exec VP & CFO Nov 13, 2013 Sale $10.00 10,000 100,000 213,219 Nov 15, 2013, 08:01 PM
LANPHIER EDWARD O II President & CEO Nov 15, 2013 Sale $10.11 25,000 252,723 1,542,452 Nov 15, 2013, 08:00 PM
Gregory Philip D Vice President, Research & CSO Nov 05, 2013 Option Exercise $4.11 7,000 28,770 97,000 Nov 05, 2013, 08:02 PM
Gregory Philip D Vice President, Research & CSO Nov 01, 2013 Option Exercise $3.45 8,000 27,600 98,000 Nov 05, 2013, 08:02 PM
Gregory Philip D Vice President, Research & CSO Nov 05, 2013 Sale $10.00 7,000 70,000 90,000 Nov 05, 2013, 08:02 PM
Gregory Philip D Vice President, Research & CSO Nov 01, 2013 Sale $9.26 8,000 74,065 90,000 Nov 05, 2013, 08:02 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Oct 28, 2013 Option Exercise $3.90 15,000 58,570 98,798 Oct 30, 2013, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Oct 28, 2013 Sale $10.39 15,000 155,779 86,798 Oct 30, 2013, 08:00 PM
Cleveland Paul B Director Oct 21, 2013 Option Exercise $4.54 10,000 45,400 10,000 Oct 23, 2013, 09:01 PM
Cleveland Paul B Director Oct 21, 2013 Sale $10.93 10,000 109,336 0 Oct 23, 2013, 09:01 PM
LANPHIER EDWARD O II President & CEO Oct 15, 2013 Sale $11.32 25,000 283,083 1,580,952 Oct 17, 2013, 08:01 PM
Wolff Henry Ward Exec VP & CFO Oct 10, 2013 Option Exercise $3.45 10,000 34,500 219,219 Oct 15, 2013, 08:02 PM
Wolff Henry Ward Exec VP & CFO Oct 10, 2013 Sale $11.28 10,000 112,763 209,219 Oct 15, 2013, 08:02 PM
Gregory Philip D Vice President, Research & CSO Oct 01, 2013 Option Exercise $4.26 15,000 63,930 105,000 Oct 04, 2013, 06:00 AM
Gregory Philip D Vice President, Research & CSO Oct 01, 2013 Sale $10.54 15,000 158,081 90,000 Oct 04, 2013, 06:00 AM
ANDO DALE G VP, Therapeutic Dev. & CMO Sep 26, 2013 Option Exercise $3.90 15,000 58,570 96,798 Sep 30, 2013, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Sep 26, 2013 Sale $10.57 15,000 158,574 84,798 Sep 30, 2013, 08:00 PM
LANPHIER EDWARD O II President & CEO Sep 16, 2013 Sale $11.29 25,000 282,127 1,605,952 Sep 18, 2013, 09:45 PM
Wolff Henry Ward Exec VP & CFO Sep 10, 2013 Option Exercise $3.45 10,000 34,500 219,219 Sep 12, 2013, 08:01 PM
Wolff Henry Ward Exec VP & CFO Sep 10, 2013 Sale $10.86 10,000 108,593 209,219 Sep 12, 2013, 08:01 PM
Gregory Philip D Vice President, Research & CSO Sep 03, 2013 Option Exercise $4.26 15,000 63,930 105,000 Sep 05, 2013, 08:02 PM
Gregory Philip D Vice President, Research & CSO Sep 03, 2013 Sale $10.33 15,000 154,981 90,000 Sep 05, 2013, 08:02 PM
Cleveland Paul B Director Sep 03, 2013 Option Exercise $2.04 7,278 14,847 7,278 Sep 05, 2013, 08:00 PM
Cleveland Paul B Director Sep 03, 2013 Sale $10.30 7,278 74,978 0 Sep 05, 2013, 08:00 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Aug 26, 2013 Option Exercise $3.84 13,000 49,930 97,798 Aug 28, 2013, 08:01 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Aug 26, 2013 Sale $10.04 15,000 150,606 86,798 Aug 28, 2013, 08:01 PM
LANPHIER EDWARD O II President & CEO Aug 15, 2013 Sale $10.12 25,000 252,880 1,630,952 Aug 16, 2013, 08:00 PM
Wolff Henry Ward Exec VP & CFO Aug 13, 2013 Option Exercise $3.45 10,000 34,500 219,219 Aug 15, 2013, 08:01 PM
Wolff Henry Ward Exec VP & CFO Aug 13, 2013 Sale $10.00 10,000 100,000 209,219 Aug 15, 2013, 08:01 PM
Gregory Philip D Vice President, Research & CSO Aug 01, 2013 Option Exercise $4.26 15,000 63,930 105,000 Aug 05, 2013, 04:20 PM
Gregory Philip D Vice President, Research & CSO Aug 01, 2013 Sale $9.89 15,000 148,321 90,000 Aug 05, 2013, 04:20 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jul 26, 2013 Option Exercise $3.84 13,000 49,930 99,798 Jul 30, 2013, 04:20 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jul 26, 2013 Sale $10.09 15,000 151,308 88,798 Jul 30, 2013, 04:20 PM
Gregory Philip D Vice President, Research & CSO Jul 29, 2013 Option Exercise $4.21 15,000 63,120 98,000 Jul 30, 2013, 04:20 PM
Gregory Philip D Vice President, Research & CSO Jul 29, 2013 Sale $10.04 15,000 150,556 90,000 Jul 30, 2013, 04:20 PM
LANPHIER EDWARD O II President & CEO Jul 17, 2013 Sale $10.00 25,000 250,003 1,655,952 Jul 19, 2013, 06:13 PM
Wolff Henry Ward Exec VP & CFO Jul 17, 2013 Option Exercise $3.45 10,000 34,500 219,219 Jul 19, 2013, 06:07 PM
Wolff Henry Ward Exec VP & CFO Jul 17, 2013 Sale $10.00 10,000 100,000 209,219 Jul 19, 2013, 06:07 PM
Cleveland Paul B Director Jul 15, 2013 Option Exercise $2.04 8,000 16,320 8,000 Jul 17, 2013, 04:30 PM
Cleveland Paul B Director Jul 15, 2013 Sale $9.59 8,000 76,718 0 Jul 17, 2013, 04:30 PM
Gregory Philip D Vice President, Research & CSO Jun 03, 2013 Option Exercise $3.45 3,000 10,350 93,000 Jun 05, 2013, 04:30 PM
Gregory Philip D Vice President, Research & CSO Jun 03, 2013 Sale $7.88 3,000 23,640 90,000 Jun 05, 2013, 04:30 PM
ANDO DALE G VP, Therapeutic Dev. & CMO May 28, 2013 Option Exercise $3.61 15,000 54,150 103,798 May 30, 2013, 04:31 PM
ANDO DALE G VP, Therapeutic Dev. & CMO May 28, 2013 Sale $8.32 15,000 124,818 88,798 May 30, 2013, 04:31 PM
LARSON JOHN WILLIAM Director May 07, 2013 Option Exercise $2.45 10,000 24,500 218,160 May 09, 2013, 04:50 PM
Gregory Philip D Vice President, Research & CSO May 01, 2013 Option Exercise $3.45 6,000 20,700 96,000 May 03, 2013, 05:36 PM
Gregory Philip D Vice President, Research & CSO May 01, 2013 Sale $10.09 6,000 60,557 90,000 May 03, 2013, 05:36 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Apr 26, 2013 Option Exercise $3.61 15,000 54,150 103,798 Apr 29, 2013, 06:16 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Apr 26, 2013 Sale $10.72 15,000 160,746 88,798 Apr 29, 2013, 06:16 PM
LANPHIER EDWARD O II President & CEO Apr 15, 2013 Sale $10.00 5,000 50,000 1,693,142 Apr 19, 2013, 06:00 AM
LANPHIER EDWARD O II President & CEO Apr 16, 2013 Sale $10.00 190 1,900 1,692,952 Apr 19, 2013, 06:00 AM
Wolff Henry Ward Exec VP & CFO Apr 10, 2013 Option Exercise $3.45 10,000 34,500 219,219 Apr 12, 2013, 04:30 PM
Wolff Henry Ward Exec VP & CFO Apr 10, 2013 Sale $10.00 10,000 100,000 209,219 Apr 12, 2013, 04:30 PM
Gregory Philip D Vice President, Research & CSO Apr 01, 2013 Option Exercise $3.45 6,000 20,700 96,000 Apr 03, 2013, 06:06 PM
Gregory Philip D Vice President, Research & CSO Apr 01, 2013 Sale $9.54 6,000 57,240 90,000 Apr 03, 2013, 06:06 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Mar 26, 2013 Option Exercise $3.61 15,000 54,150 103,798 Mar 28, 2013, 05:44 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Mar 26, 2013 Sale $9.18 15,000 137,724 88,798 Mar 28, 2013, 05:44 PM
Gregory Philip D Vice President, Research & CSO Mar 01, 2013 Option Exercise $4.92 6,000 29,520 96,000 Mar 01, 2013, 06:36 PM
Gregory Philip D Vice President, Research & CSO Mar 01, 2013 Sale $10.00 6,000 60,005 90,000 Mar 01, 2013, 06:36 PM
Wolff Henry Ward Exec VP & CFO Feb 28, 2013 Option Exercise $3.45 10,000 34,500 219,219 Mar 01, 2013, 06:34 PM
Wolff Henry Ward Exec VP & CFO Feb 28, 2013 Sale $10.00 10,000 100,000 209,219 Mar 01, 2013, 06:34 PM
LANPHIER EDWARD O II President & CEO Feb 28, 2013 Sale $10.00 25,000 250,000 1,698,142 Mar 01, 2013, 06:32 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Feb 26, 2013 Option Exercise $3.61 15,000 54,150 103,798 Feb 28, 2013, 06:15 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Feb 26, 2013 Sale $8.64 15,000 129,600 88,798 Feb 28, 2013, 06:15 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jan 28, 2013 Option Exercise $3.61 15,000 54,150 103,798 Feb 28, 2013, 06:11 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jan 28, 2013 Sale $9.68 15,000 145,158 88,798 Feb 28, 2013, 06:11 PM
Gregory Philip D Vice President, Research & CSO Feb 01, 2013 Option Exercise $4.92 6,000 29,520 96,000 Feb 05, 2013, 04:15 PM
Gregory Philip D Vice President, Research & CSO Feb 01, 2013 Sale $9.53 6,000 57,195 90,000 Feb 05, 2013, 04:15 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jan 28, 2012 Option Exercise $3.61 15,000 54,150 103,798 Jan 30, 2013, 04:17 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jan 28, 2012 Sale $9.68 15,000 145,158 88,798 Jan 30, 2013, 04:17 PM
Wolff Henry Ward Exec VP & CFO Jan 23, 2013 Option Exercise $3.45 8,000 27,600 219,219 Jan 28, 2013, 06:01 AM
Wolff Henry Ward Exec VP & CFO Jan 23, 2013 Sale $10.00 10,000 100,000 209,219 Jan 28, 2013, 06:01 AM
LANPHIER EDWARD O II President & CEO Jan 24, 2013 Sale $10.00 300 3,000 1,723,142 Jan 28, 2013, 06:01 AM
LANPHIER EDWARD O II President & CEO Jan 23, 2013 Sale $10.00 8,300 83,008 1,723,442 Jan 28, 2013, 06:01 AM
Gregory Philip D Vice President, Research & CSO Jan 02, 2013 Option Exercise $4.92 6,000 29,520 96,000 Jan 04, 2013, 06:14 PM
Gregory Philip D Vice President, Research & CSO Jan 02, 2013 Sale $6.05 6,000 36,300 90,000 Jan 04, 2013, 06:14 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 26, 2012 Option Exercise $3.61 15,000 54,150 103,798 Dec 28, 2012, 04:06 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Dec 26, 2012 Sale $5.92 17,000 100,718 88,798 Dec 28, 2012, 04:06 PM
Gregory Philip D Vice President, Research & CSO Dec 10, 2012 Sale $5.46 24,000 131,040 102,000 Dec 10, 2012, 08:40 PM
LARSON JOHN WILLIAM Director Dec 03, 2012 Sale $5.64 15,000 84,634 222,160 Dec 05, 2012, 06:06 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Nov 27, 2012 Option Exercise $3.61 15,000 54,150 70,798 Nov 28, 2012, 07:35 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Nov 26, 2012 Sale $5.33 4,736 25,232 55,798 Nov 28, 2012, 07:35 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Nov 27, 2012 Sale $5.60 15,000 84,000 55,798 Nov 28, 2012, 07:35 PM
LARSON JOHN WILLIAM Director Nov 01, 2012 Sale $5.52 15,000 82,764 223,160 Nov 05, 2012, 06:15 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Oct 26, 2012 Option Exercise $3.61 15,000 54,150 78,534 Oct 29, 2012, 09:53 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Oct 26, 2012 Sale $5.70 20,000 113,935 63,534 Oct 29, 2012, 09:53 PM
Gregory Philip D VP, Therapeutic Dev. & CMO Oct 17, 2012 Option Exercise $4.92 6,000 29,520 56,000 Oct 17, 2012, 09:05 PM
Gregory Philip D VP, Therapeutic Dev. & CMO Oct 17, 2012 Sale $6.00 6,000 36,000 50,000 Oct 17, 2012, 09:05 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Oct 15, 2012 Sale $5.66 5,000 28,283 67,534 Oct 17, 2012, 05:58 PM
LARSON JOHN WILLIAM Director Oct 01, 2012 Sale $6.20 15,000 93,035 252,860 Oct 03, 2012, 05:51 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Sep 05, 2012 Option Exercise $3.61 15,000 54,150 83,534 Sep 06, 2012, 05:51 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Sep 05, 2012 Sale $5.60 15,000 84,000 68,534 Sep 06, 2012, 05:51 PM
LARSON JOHN WILLIAM Director Sep 04, 2012 Sale $5.30 15,000 79,494 268,060 Sep 06, 2012, 05:46 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Aug 27, 2012 Sale $5.18 5,000 25,903 72,364 Aug 29, 2012, 07:07 PM
LARSON JOHN WILLIAM Director Aug 01, 2012 Sale $5.25 15,000 78,825 282,460 Aug 03, 2012, 05:27 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jul 27, 2012 Option Exercise $3.61 15,000 54,150 88,534 Jul 30, 2012, 04:58 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jul 27, 2012 Sale $5.60 15,000 84,000 73,534 Jul 30, 2012, 04:58 PM
ANDO DALE G VP, Therapeutic Dev. & CMO Jul 26, 2012 Sale $5.06 5,000 25,320 77,534 Jul 30, 2012, 04:58 PM
LARSON JOHN WILLIAM Director Jul 02, 2012 Sale $5.24 15,000 78,556 296,619 Jul 03, 2012, 04:02 PM
LARSON JOHN WILLIAM Director Jun 15, 2012 Sale $5.00 15,000 75,000 298,160 Jun 19, 2012, 05:18 PM
Wolff Henry Ward Exec VP & CFO Dec 30, 2011 Option Exercise $2.84 2,234 6,345 162,219 Jan 04, 2012, 06:08 PM
Wolff Henry Ward Exec VP & CFO Sep 30, 2011 Option Exercise $4.35 2,234 9,718 87,453 Oct 04, 2011, 04:48 PM
Gregory Philip D CSO & Vice President, Research Sep 09, 2011 Option Exercise $3.45 2,500 8,625 2,500 Sep 14, 2011, 07:18 PM
Gregory Philip D CSO & Vice President, Research Sep 09, 2011 Option Exercise $3.00 2,500 7,500 2,500 Sep 13, 2011, 08:48 PM
Gregory Philip D CSO & Vice President, Research Sep 09, 2011 Sale $6.00 2,500 15,000 0 Sep 13, 2011, 08:48 PM
Ichikawa David G Senior VP, Bus. Dev. Jul 07, 2011 Option Exercise $5.19 4,000 20,760 4,000 Jul 11, 2011, 08:04 PM
Ichikawa David G Senior VP, Bus. Dev. Jul 07, 2011 Sale $6.47 4,000 25,880 0 Jul 11, 2011, 08:04 PM
Wolff Henry Ward Exec VP & CFO Jun 30, 2011 Option Exercise $5.89 2,234 13,158 89,687 Jul 05, 2011, 05:17 PM
Gregory Philip D CSO & Vice President, Research Jul 01, 2011 Option Exercise $3.45 15,000 51,750 15,000 Jul 05, 2011, 05:15 PM
Gregory Philip D CSO & Vice President, Research Jul 01, 2011 Sale $6.00 15,000 90,000 0 Jul 05, 2011, 05:15 PM
Ichikawa David G Senior VP, Bus. Dev. Jun 06, 2011 Option Exercise $5.19 4,000 20,760 4,000 Jun 08, 2011, 06:05 PM
Ichikawa David G Senior VP, Bus. Dev. Jun 06, 2011 Sale $6.52 4,000 26,080 0 Jun 08, 2011, 06:05 PM
Gregory Philip D CSO & Vice President, Research Jun 01, 2011 Option Exercise $3.45 15,000 51,750 15,000 Jun 03, 2011, 05:32 PM
Gregory Philip D CSO & Vice President, Research Jun 01, 2011 Sale $6.80 15,000 102,012 14,894 Jun 03, 2011, 05:32 PM
Ichikawa David G Senior VP, Bus. Dev. May 05, 2011 Option Exercise $5.19 4,000 20,760 4,000 May 09, 2011, 05:20 PM
Ichikawa David G Senior VP, Bus. Dev. May 05, 2011 Sale $6.74 4,000 26,960 0 May 09, 2011, 05:20 PM
Gregory Philip D CSO & Vice President, Research May 02, 2011 Option Exercise $3.45 15,000 51,750 15,000 May 04, 2011, 05:57 PM
Gregory Philip D CSO & Vice President, Research May 02, 2011 Sale $7.33 15,000 109,930 13,500 May 04, 2011, 05:57 PM
Gregory Philip D CSO & Vice President, Research Apr 25, 2011 Option Exercise $3.32 15,000 49,856 19,433 Apr 27, 2011, 07:10 PM
Gregory Philip D CSO & Vice President, Research Apr 25, 2011 Sale $7.54 19,433 146,508 17,785 Apr 27, 2011, 07:10 PM
Ichikawa David G Senior VP, Bus. Dev. Apr 21, 2011 Option Exercise $5.19 8,000 41,520 8,000 Apr 25, 2011, 05:32 PM
Ichikawa David G Senior VP, Bus. Dev. Apr 21, 2011 Sale $7.70 8,000 61,625 7,900 Apr 25, 2011, 05:32 PM
Wolff Henry Ward Exec VP & CFO Mar 31, 2011 Option Exercise $8.33 2,235 18,618 89,921 Apr 04, 2011, 05:34 PM
Cleveland Paul B Director Feb 28, 2011 Option Exercise $2.04 1,388 2,832 1,388 Mar 02, 2011, 06:46 PM
Cleveland Paul B Director Feb 28, 2011 Sale $9.00 1,388 12,492 0 Mar 02, 2011, 06:46 PM
Gregory Philip D CSO & Vice President, Research Mar 01, 2011 Sale $8.29 2,500 20,715 6,893 Mar 02, 2011, 06:45 PM
Gregory Philip D CSO & Vice President, Research Feb 28, 2011 Sale $9.00 2,500 22,500 6,933 Mar 02, 2011, 06:45 PM
Gregory Philip D CSO & Vice President, Research Feb 01, 2011 Sale $7.97 2,500 19,925 11,633 Feb 03, 2011, 05:14 PM
Gregory Philip D CSO & Vice President, Research Jan 03, 2011 Sale $6.80 2,500 17,000 11,933 Jan 05, 2011, 04:42 PM
Wolff Henry Ward Exec VP & CFO Dec 31, 2010 Option Exercise $6.64 2,234 14,834 92,156 Jan 04, 2011, 04:36 PM
Cleveland Paul B Director Dec 22, 2010 Option Exercise $2.68 32,037 85,955 32,037 Dec 23, 2010, 07:52 PM
Cleveland Paul B Director Dec 22, 2010 Sale $7.00 32,037 224,259 10,000 Dec 23, 2010, 07:52 PM
Cleveland Paul B Director Dec 20, 2010 Option Exercise $2.04 11,297 23,046 11,297 Dec 22, 2010, 05:27 PM
Cleveland Paul B Director Dec 20, 2010 Sale $7.00 11,297 79,079 0 Dec 22, 2010, 05:27 PM
Gregory Philip D CSO & Vice President, Research Dec 08, 2010 Sale $6.00 2,500 15,000 12,433 Dec 10, 2010, 05:04 PM
Wolff Henry Ward Exec VP & CFO Sep 30, 2010 Option Exercise $3.43 2,239 7,680 92,390 Oct 04, 2010, 04:15 PM
LANPHIER EDWARD O II President & CEO Aug 30, 2010 Buy $3.01 10,000 30,050 1,661,242 Aug 30, 2010, 06:09 PM
Wolff Henry Ward Exec VP & CFO Aug 30, 2010 Buy $3.00 9,000 27,000 94,629 Aug 30, 2010, 06:09 PM
Load More Insider Transactions
Buy Sale Option Exercise
Owner Relationship Date Value($)
Willoughby Scott B. SVP, Gen. Counsel & Secretary 04/29/2022 581
Fontenot Jason D. SVP, Chief Scientific Officer 04/25/2022 3,990
Duraibabu Prathyusha Vice President, Finance 04/25/2022 3,197
Willoughby Scott B. SVP, Gen. Counsel & Secretary 04/24/2022 18,687
Duraibabu Prathyusha Vice President, Finance 03/25/2022 1,984
Willoughby Scott B. SVP, Gen. Counsel & Secretary 02/25/2022 9,239
Ramelmeier Rolf Andrew EVP, Technical Operations 02/25/2022 73,089
Fontenot Jason D. SVP, Chief Scientific Officer 02/25/2022 36,863
Duraibabu Prathyusha Vice President, Finance 02/25/2022 20,497
McClung David Mark EVP, Chief Operating Officer 02/25/2022 27,199
Macrae Sandy President, CEO and Director 02/25/2022 294,351
Schott Robert J. SVP, Head of Development 02/12/2022 31,467
BIOGEN INC. 10% Owner 12/28/2021 23,522
BIOGEN INC. 10% Owner 12/23/2021 694,530
BIOGEN INC. 10% Owner 12/27/2021 5,136
BIOGEN INC. 10% Owner 12/09/2021 202,541
BIOGEN INC. 10% Owner 12/08/2021 654,828
BIOGEN INC. 10% Owner 12/07/2021 444,437
BIOGEN INC. 10% Owner 12/01/2021 6,223
BIOGEN INC. 10% Owner 12/02/2021 15,943
BIOGEN INC. 10% Owner 11/26/2021 248,434
Willoughby Scott B. SVP, Gen. Counsel & Secretary 10/29/2021 1,137
McClung David Mark EVP, Chief Business Officer 06/25/2021 138,531
Fontenot Jason D. SVP, Chief Scientific Officer 04/25/2021 9,497
Duraibabu Prathyusha VP, PFO and PAO 04/25/2021 7,752
Duraibabu Prathyusha VP, PFO and PAO 03/25/2021 4,233
LOEB GARY EVP, General Counsel & Sec. 03/23/2021 132,031
LOEB GARY EVP, General Counsel & Sec. 03/23/2021 230,042
Duraibabu Prathyusha VP Principal Acct. Officer 02/25/2021 20,847
Ramelmeier Rolf Andrew EVP, Technical Operations 02/25/2021 87,047
LOEB GARY EVP, General Counsel & Sec. 02/25/2021 64,477
Macrae Sandy President and CEO 02/25/2021 395,130
Macrae Sandy President and CEO 01/24/2021 59,456
Ramelmeier Rolf Andrew EVP, Technical Operations 12/31/2020 41,247
Ramelmeier Rolf Andrew EVP, Technical Operations 12/24/2020 60,391
Ramasastry Saira Director 12/17/2020 59,900
Ramasastry Saira Director 12/17/2020 132,747
Lee Sung EVP, Chief Financial Officer 11/25/2020 49,260
Boissel Stephane EVP, Corp. Strategy 06/04/2020 167,406
Duraibabu Prathyusha VP Principal Acct. Officer 04/25/2020 5,383
DILLY STEPHEN GEORGE Director 03/19/2020 189,700
DILLY STEPHEN GEORGE Director 03/19/2020 210,000
PARKER H STEWART Director 03/18/2020 15,585
Zakrzewski Joseph S Director 03/17/2020 24,950
DILLY STEPHEN GEORGE Director 03/16/2020 81,300
DILLY STEPHEN GEORGE Director 03/16/2020 90,261
Zakrzewski Joseph S Director 03/13/2020 28,350
Zakrzewski Joseph S Director 03/12/2020 94,650
Ramelmeier Rolf Andrew EVP, Technical Operations 02/25/2020 11,580
Boissel Stephane EVP, Corp. Strategy 02/25/2020 16,211
Macrae Sandy President and CEO 02/25/2020 49,395
Macrae Sandy President and CEO 01/24/2020 32,123
Boissel Stephane EVP, Corp. Strat. & Int. CFO 08/12/2019 125,069
Yi Kathy EVP & Chief Financial Officer 05/15/2019 22,750
Yi Kathy EVP & Chief Financial Officer 05/15/2019 50,000
Yi Kathy EVP & Chief Financial Officer 04/15/2019 22,750
Yi Kathy EVP & Chief Financial Officer 04/15/2019 60,550
Yi Kathy EVP & Chief Financial Officer 03/15/2019 22,750
Yi Kathy EVP & Chief Financial Officer 03/15/2019 50,000
Yi Kathy EVP & Chief Financial Officer 03/01/2019 22,750
Yi Kathy EVP & Chief Financial Officer 03/01/2019 50,000
Conner Edward R. Sr. VP & Chief Medical Officer 01/24/2019 9,257
Yi Kathy SVP & Chief Financial Officer 01/24/2019 10,967
Macrae Sandy President and CEO 01/24/2018 44,111
Yi Kathy SVP & Chief Financial Officer 01/15/2019 22,750
Yi Kathy SVP & Chief Financial Officer 01/15/2019 55,200
Conner Edward R. Sr. VP & Chief Medical Officer 01/07/2019 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 01/07/2019 61,631
Yi Kathy SVP & Chief Financial Officer 12/17/2018 22,750
Yi Kathy SVP & Chief Financial Officer 12/17/2018 57,200
Conner Edward R. Sr. VP & Chief Medical Officer 12/06/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 12/06/2018 57,433
Yi Kathy SVP & Chief Financial Officer 11/15/2018 22,750
Yi Kathy SVP & Chief Financial Officer 11/15/2018 50,000
PARKER H STEWART Director 11/14/2018 18,002
Conner Edward R. Sr. VP & Chief Medical Officer 11/06/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 11/06/2018 68,650
Yi Kathy SVP & Chief Financial Officer 10/15/2018 22,750
Yi Kathy SVP & Chief Financial Officer 10/15/2018 69,850
Conner Edward R. Sr. VP & Chief Medical Officer 10/08/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 10/08/2018 72,773
Yi Kathy SVP & Chief Financial Officer 09/17/2018 22,750
Yi Kathy SVP & Chief Financial Officer 09/17/2018 73,285
JEFFS ROGER Director 09/07/2018 100,487
PARKER H STEWART Director 09/07/2018 27,040
Conner Edward R. Sr. VP & Chief Medical Officer 09/06/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 09/06/2018 70,845
Yi Kathy SVP & Chief Financial Officer 08/16/2018 22,750
Yi Kathy SVP & Chief Financial Officer 08/16/2018 76,951
Conner Edward R. Sr. VP & Chief Medical Officer 08/06/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 08/06/2018 67,250
Yi Kathy SVP & Chief Financial Officer 07/16/2018 22,750
Yi Kathy SVP & Chief Financial Officer 07/16/2018 73,860
Conner Edward R. Sr. VP & Chief Medical Officer 07/06/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 07/06/2018 78,975
Yi Kathy SVP & Chief Financial Officer 06/15/2018 22,750
Yi Kathy SVP & Chief Financial Officer 06/15/2018 78,365
Conner Edward R. Sr. VP & Chief Medical Officer 06/06/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 06/06/2018 83,350
Yi Kathy SVP & Chief Financial Officer 05/15/2018 22,750
Yi Kathy SVP & Chief Financial Officer 05/15/2018 76,920
Conner Edward R. Sr. VP & Chief Medical Officer 05/07/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 05/07/2018 81,814
Yi Kathy SVP & Chief Financial Officer 04/16/2018 22,750
Yi Kathy SVP & Chief Financial Officer 04/16/2018 99,144
Herberts Curt A. III Sr.VP & Chief Business Officer 04/13/2018 114,853
Herberts Curt A. III Sr.VP & Chief Business Officer 04/13/2018 163,260
Conner Edward R. Sr. VP & Chief Medical Officer 04/06/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 04/06/2018 87,065
Mento Steven J Director 04/02/2018 77,700
Mento Steven J Director 04/02/2018 132,758
Herberts Curt A. III Sr.VP & Chief Business Officer 04/02/2018 12,199
Herberts Curt A. III Sr.VP & Chief Business Officer 04/02/2018 41,684
Yi Kathy SVP & Chief Financial Officer 03/15/2018 22,750
Yi Kathy SVP & Chief Financial Officer 03/15/2018 127,812
Conner Edward R. Sr. VP & Chief Medical Officer 03/06/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 03/06/2018 123,877
Mento Steven J Director 03/01/2018 82,350
Mento Steven J Director 03/01/2018 219,546
Herberts Curt A. III Sr.VP & Chief Business Officer 03/01/2018 147,905
Herberts Curt A. III Sr.VP & Chief Business Officer 03/01/2018 345,861
Ramasastry Saira Director 02/26/2018 47,534
Ramasastry Saira Director 02/26/2018 235,080
Conner Edward R. Sr. VP & Chief Medical Officer 02/06/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 02/06/2018 92,436
Mento Steven J Director 02/01/2018 133,750
Mento Steven J Director 02/01/2018 237,159
Herberts Curt A. III Sr.VP & Chief Business Officer 02/01/2018 52,500
Herberts Curt A. III Sr.VP & Chief Business Officer 02/01/2018 308,854
Conner Edward R. Sr. VP & Chief Medical Officer 01/08/2018 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 01/08/2018 85,545
Herberts Curt A. III Sr.VP & Chief Business Officer 01/03/2018 97,275
Herberts Curt A. III Sr.VP & Chief Business Officer 01/02/2018 9,212
Herberts Curt A. III Sr.VP & Chief Business Officer 01/03/2018 144,869
Herberts Curt A. III Sr.VP & Chief Business Officer 01/02/2018 114,025
Herberts Curt A. III Sr.VP & Chief Business Officer 12/08/2017 39,681
Herberts Curt A. III Sr.VP & Chief Business Officer 12/11/2017 19,844
Conner Edward R. Sr. VP & Chief Medical Officer 12/06/2017 16,000
Conner Edward R. Sr. VP & Chief Medical Officer 12/06/2017 81,200
Herberts Curt A. III Sr.VP & Chief Business Officer 12/04/2017 143,052
Herberts Curt A. III Sr.VP & Chief Business Officer 12/04/2017 212,454
Herberts Curt A. III Sr.VP & Chief Business Officer 12/01/2017 11,039
Herberts Curt A. III Sr.VP & Chief Business Officer 11/30/2017 126,405
Herberts Curt A. III Sr.VP & Chief Business Officer 11/30/2017 214,928
Herberts Curt A. III Sr.VP & Chief Business Officer 12/01/2017 53,390
Herberts Curt A. III Sr.VP & Chief Business Officer 11/30/2017 126,405
Herberts Curt A. III Sr.VP & Chief Business Officer 12/01/2017 11,039
Herberts Curt A. III Sr.VP & Chief Business Officer 11/30/2017 214,928
Herberts Curt A. III Sr.VP & Chief Business Officer 12/01/2017 53,390
Ramasastry Saira Director 11/17/2017 25,150
Ramasastry Saira Director 11/17/2017 73,339
Herberts Curt A. III Sr.VP & Chief Business Officer 10/02/2017 114,905
Herberts Curt A. III Sr.VP & Chief Business Officer 10/02/2017 228,754
RINGO WILLIAM R Director 09/20/2017 187,550
RINGO WILLIAM R Director 09/20/2017 445,597
Herberts Curt A. III Sr.VP & Chief Business Officer 09/01/2017 55,810
Herberts Curt A. III Sr.VP & Chief Business Officer 09/01/2017 225,000
Herberts Curt A. III Sr.VP & Chief Business Officer 08/14/2017 25,600
Herberts Curt A. III Sr.VP & Chief Business Officer 08/11/2017 21,511
Herberts Curt A. III Sr.VP & Chief Business Officer 08/11/2017 64,740
Herberts Curt A. III Sr.VP & Chief Business Officer 08/14/2017 55,000
Herberts Curt A. III Sr.VP & Chief Business Officer 07/14/2017 686
Herberts Curt A. III Sr.VP & Chief Business Officer 07/14/2017 150,000
Herberts Curt A. III Senior VP & CBO 06/01/2017 13,600
Herberts Curt A. III Senior VP & CBO 05/12/2017 17,000
Herberts Curt A. III Senior VP & CBO 05/11/2017 4,154
Herberts Curt A. III Senior VP & CBO 12/12/2016 14,799
Wolff Henry Ward Exec VP & CFO 12/12/2015 42,023
LANPHIER EDWARD O II Director 06/13/2016 527,320
ANDO DALE G VP, Therapeutic Dev. & CMO 12/11/2015 37,741
ANDO DALE G VP, Therapeutic Dev. & CMO 12/12/2015 34,720
LANPHIER EDWARD O II President & CEO 12/12/2015 113,231
LANPHIER EDWARD O II President & CEO 12/11/2015 188,712
NICHOL GEOFFREY Executive Vice President, R&D 12/12/2015 38,053
NICHOL GEOFFREY Executive Vice President, R&D 12/11/2015 40,770
Wolff Henry Ward Exec VP & CFO 12/11/2015 56,611
Wolff Henry Ward Exec VP & CFO 12/12/2015 52,835
ANDO DALE G VP, Therapeutic Dev. & CMO 12/07/2015 58,983
LANPHIER EDWARD O II President & CEO 12/07/2015 303,375
NICHOL GEOFFREY Executive Vice President, R&D 12/07/2015 66,754
Wolff Henry Ward Exec VP & CFO 12/07/2015 68,411
LANPHIER EDWARD O II President & CEO 07/15/2015 170,500
LANPHIER EDWARD O II President & CEO 07/15/2015 260,770
Wolff Henry Ward Exec VP & CFO 07/10/2015 21,052
Wolff Henry Ward Exec VP & CFO 07/13/2015 13,448
Wolff Henry Ward Exec VP & CFO