Prelude Therapeutics Inc. (PRLD) NASDAQ

$4.45 -0.42 (-8.62%)

Market Cap: $212.25M

As of 05/18/22 04:00 PM EDT. Market closed.

(PRLD)

Prelude Therapeutics Inc. (PRLD) NASDAQ

$4.45 -0.42 (-8.62%)

Market Cap: $212.25M

As of 05/18/22 04:00 PM EDT. Market closed.

Prelude Therapeutics is a clinical-stage precision oncology company developing innovative drug candidates targeting critical cancer cell pathways. The Company’s lead product candidates are designed to be oral, potent, and selective inhibitors of PRMT5. Prelude’s first clinical candidate, PRT543, is in Phase 1 development for advanced solid tumors and select myeloid malignancies. Prelude is ... read more

Prelude Therapeutics is a clinical-stage precision oncology company developing innovative drug candidates targeting critical cancer cell pathways. The Company’s lead product candidates are designed to be oral, potent, and selective inhibitors of PRMT5. Prelude’s first clinical candidate, PRT543, is in Phase 1 development for advanced solid tumors and select myeloid malignancies. Prelude is also advancing PRT811, a second PRMT5 inhibitor optimized for high brain exposure, in a Phase 1 clinical trial including glioblastoma multiforme (GBM). The Company’s pipeline also includes its third clinical candidate, PRT1419, an orally available MCL1 inhibitor in Phase 1 development for patients with relapsed/refractory hematologic malignancies, and its two most advanced preclinical candidates, PRT2527, a CDK9 inhibitor, and PRT-SCA2, a SMARCA2 protein degrader. read less

COMPANY PROFILE
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
URL
Address
.
Sector
Manufacturing
Industry
Pharmaceutical Preparation Manufacturing
Full Time Employees
68
Address
.
PRICE CHART
1w
1m
3m
6m
YTD
1y
5y
MAX
From: To:
KEY STATS
Open
$4.68
Previous Close
$4.87
Days Range
$4.42 - $4.80
52 week range
$3.87 - $43.55
Volume
193,314
Avg. Volume (30 days)
326,248
Market Cap
$212.25M
Dividend Yield
0.00%
P/E
-
Shares Outstanding
47,695,639
Open
$4.68
Previous Close
$4.87
Days Range
$4.42 - $4.80
52 week range
$3.87 - $43.55
Volume
193,314
Avg. Volume (30 days)
326,248
Market Cap
$212.25M
Dividend Yield
0.00%
P/E
-
Shares Outstanding
47,695,639

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

INSIDER TRANSACTIONS FOR PRELUDE THERAPEUTICS INC
Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
Combs Andrew EVP, Head of Chemistry Mar 31, 2022 Option Exercise $1.89 36,062 68,157 304,442 Apr 04, 2022, 05:08 PM
Chardonnet Laurent Chief Financial Officer Mar 21, 2022 Option Exercise $7.51 6,500 48,815 14,500 Mar 22, 2022, 06:01 PM
Morosini Deborah EVP, Chief of Clinical Affairs Dec 15, 2021 Option Exercise $11.70 28,751 336,395 29,195 Dec 17, 2021, 05:20 PM
Morosini Deborah EVP, Chief of Clinical Affairs Dec 15, 2021 Sale $13.00 28,751 373,763 444 Dec 17, 2021, 05:20 PM
Combs Andrew EVP, Head of Chemistry Dec 14, 2021 Buy $11.60 4,000 46,400 268,380 Dec 15, 2021, 05:21 PM
Combs Andrew EVP, Head of Chemistry Dec 13, 2021 Buy $12.12 4,000 48,480 264,380 Dec 15, 2021, 05:21 PM
Chardonnet Laurent Chief Financial Officer Dec 13, 2021 Option Exercise $12.28 5,000 61,400 8,000 Dec 14, 2021, 05:37 PM
Vaddi Krishna President, CEO Dec 13, 2021 Option Exercise $12.13 8,000 97,035 1,053,519 Dec 14, 2021, 05:36 PM
Morosini Deborah EVP, Chief of Clinical Affairs Nov 16, 2021 Option Exercise $12.85 28,751 369,450 29,195 Nov 18, 2021, 06:42 PM
Morosini Deborah EVP, Chief of Clinical Affairs Nov 16, 2021 Sale $15.88 28,751 456,532 844 Nov 18, 2021, 06:42 PM
Mauro David J Chief Medical Officer Oct 05, 2021 Option Exercise $1.89 15,000 28,350 15,000 Oct 06, 2021, 06:02 PM
Mauro David J Chief Medical Officer Oct 05, 2021 Sale $30.96 15,000 464,350 9,092 Oct 06, 2021, 06:02 PM
Mauro David J Chief Medical Officer Sep 07, 2021 Option Exercise $1.89 15,000 28,350 15,000 Sep 09, 2021, 04:53 PM
Mauro David J Chief Medical Officer Sep 07, 2021 Sale $36.69 15,000 550,283 7,513 Sep 09, 2021, 04:53 PM
Pierce Christopher EVP and Chief of Business Oper Sep 02, 2021 Option Exercise $12.85 17,000 218,450 20,750 Sep 07, 2021, 07:17 PM
Pierce Christopher EVP and Chief of Business Oper Sep 02, 2021 Sale $41.68 17,000 708,493 17,407 Sep 07, 2021, 07:17 PM
Scherle Peggy Chief Scientific Officer Aug 26, 2021 Option Exercise $1.43 1,700 2,431 174,620 Aug 30, 2021, 05:16 PM
Scherle Peggy Chief Scientific Officer Aug 27, 2021 Option Exercise $1.43 6,014 8,600 178,934 Aug 30, 2021, 05:16 PM
Scherle Peggy Chief Scientific Officer Aug 27, 2021 Sale $35.91 6,014 215,967 176,234 Aug 30, 2021, 05:16 PM
Scherle Peggy Chief Scientific Officer Aug 26, 2021 Sale $35.19 1,700 59,819 172,920 Aug 30, 2021, 05:16 PM
Piper Brian Chief Financial Officer Aug 25, 2021 Option Exercise $1.89 8,333 15,749 8,333 Aug 27, 2021, 08:02 PM
Piper Brian Chief Financial Officer Aug 25, 2021 Sale $33.34 8,333 277,827 6,233 Aug 27, 2021, 08:02 PM
Scherle Peggy Chief Scientific Officer Aug 13, 2021 Option Exercise $1.54 2,286 3,526 175,206 Aug 17, 2021, 04:44 PM
Scherle Peggy Chief Scientific Officer Aug 13, 2021 Sale $35.07 2,286 80,161 172,920 Aug 17, 2021, 04:44 PM
Mauro David J Chief Medical Officer Aug 05, 2021 Option Exercise $1.89 15,000 28,350 15,000 Aug 09, 2021, 04:26 PM
Mauro David J Chief Medical Officer Aug 05, 2021 Sale $31.09 15,000 466,394 8,884 Aug 09, 2021, 04:26 PM
Scherle Peggy Chief Scientific Officer Jul 27, 2021 Option Exercise $1.43 20,000 28,600 192,920 Jul 29, 2021, 07:27 PM
Scherle Peggy Chief Scientific Officer Jul 27, 2021 Sale $35.47 20,000 709,380 173,600 Jul 29, 2021, 07:27 PM
Mauro David J Chief Medical Officer Jul 06, 2021 Option Exercise $1.89 15,000 28,350 15,000 Jul 08, 2021, 05:41 PM
Mauro David J Chief Medical Officer Jul 06, 2021 Sale $27.47 15,000 412,107 4,555 Jul 08, 2021, 05:41 PM
Mauro David J Chief Medical Officer Jun 07, 2021 Option Exercise $1.89 15,000 28,350 15,000 Jun 09, 2021, 06:24 PM
Mauro David J Chief Medical Officer Jun 07, 2021 Sale $32.44 15,000 486,622 13,600 Jun 09, 2021, 06:24 PM
Piper Brian Chief Financial Officer May 25, 2021 Option Exercise $1.89 8,333 15,749 8,333 May 27, 2021, 05:03 PM
Piper Brian Chief Financial Officer May 25, 2021 Sale $34.27 8,333 285,537 5,223 May 27, 2021, 05:03 PM
Scherle Peggy Chief Scientific Officer May 07, 2021 Option Exercise $1.43 10,000 14,300 182,920 May 11, 2021, 06:46 PM
Scherle Peggy Chief Scientific Officer May 07, 2021 Sale $40.82 10,000 408,192 178,956 May 11, 2021, 06:46 PM
Pierce Christopher EVP and Chief of Business Oper Apr 29, 2021 Option Exercise $1.89 3,295 6,228 7,045 Apr 30, 2021, 06:24 PM
Pierce Christopher EVP and Chief of Business Oper Apr 29, 2021 Sale $40.29 3,295 132,765 3,750 Apr 30, 2021, 06:24 PM
Morosini Deborah EVP, Chief of Clinical Affairs Apr 29, 2021 Option Exercise $1.89 3,223 6,091 3,667 Apr 30, 2021, 06:22 PM
Morosini Deborah EVP, Chief of Clinical Affairs Apr 29, 2021 Sale $40.29 3,223 129,853 444 Apr 30, 2021, 06:22 PM
Mauro David J Chief Medical Officer Apr 19, 2021 Option Exercise $1.89 25,000 47,250 25,000 Apr 21, 2021, 07:56 PM
Mauro David J Chief Medical Officer Apr 19, 2021 Sale $30.89 25,000 772,349 4,000 Apr 21, 2021, 07:56 PM
Pierce Christopher EVP and Chief of Business Oper Apr 08, 2021 Option Exercise $1.89 200 378 3,950 Apr 15, 2021, 07:12 PM
Pierce Christopher EVP and Chief of Business Oper Apr 08, 2021 Sale $40.00 200 8,000 3,750 Apr 15, 2021, 07:12 PM
Morosini Deborah EVP, Chief of Clinical Affairs Apr 08, 2021 Option Exercise $1.89 100 189 544 Apr 15, 2021, 07:11 PM
Morosini Deborah EVP, Chief of Clinical Affairs Apr 08, 2021 Sale $40.00 100 4,000 444 Apr 15, 2021, 07:11 PM
Mauro David J Chief Medical Officer Apr 08, 2021 Option Exercise $1.89 9,617 18,176 9,617 Apr 15, 2021, 07:09 PM
Mauro David J Chief Medical Officer Apr 08, 2021 Sale $38.35 9,617 368,852 6,343 Apr 15, 2021, 07:09 PM
Scherle Peggy Chief Scientific Officer Apr 07, 2021 Option Exercise $1.43 15,370 21,979 188,290 Apr 09, 2021, 05:55 PM
Scherle Peggy Chief Scientific Officer Apr 07, 2021 Sale $39.31 15,370 604,144 180,001 Apr 09, 2021, 05:55 PM
Pierce Christopher EVP and Chief of Business Oper Apr 07, 2021 Option Exercise $1.89 828 1,565 4,578 Apr 09, 2021, 05:53 PM
Pierce Christopher EVP and Chief of Business Oper Apr 07, 2021 Sale $40.08 828 33,188 3,750 Apr 09, 2021, 05:53 PM
Morosini Deborah EVP, Chief of Clinical Affairs Apr 07, 2021 Option Exercise $1.89 1,000 1,890 1,444 Apr 09, 2021, 05:52 PM
Morosini Deborah EVP, Chief of Clinical Affairs Apr 07, 2021 Sale $40.04 1,000 40,043 444 Apr 09, 2021, 05:52 PM
Mauro David J Chief Medical Officer Apr 07, 2021 Option Exercise $1.89 15,383 29,074 15,383 Apr 09, 2021, 05:50 PM
Mauro David J Chief Medical Officer Apr 07, 2021 Sale $39.33 15,383 605,023 7,083 Apr 09, 2021, 05:50 PM
BAKER BROS. ADVISORS LP Director Jan 27, 2021 Option Exercise $12.85 10,376 133,332 9,252,951 Jan 29, 2021, 07:04 PM
Bonita David P Director Sep 25, 2020 Buy $19.00 1,236,800 23,499,200 917,412 Sep 30, 2020, 07:52 PM
BAKER BROS. ADVISORS LP Director Sep 29, 2020 Buy $19.00 1,578,947 29,999,993 9,247,763 Sep 30, 2020, 06:37 PM
Combs Andrew EVP, Head of Chemistry Sep 29, 2020 Buy $19.00 1,000 19,000 260,380 Sep 29, 2020, 08:11 PM
ORBIMED ADVISORS LLC Director Sep 25, 2020 Buy $19.00 1,236,800 23,499,200 917,412 Sep 29, 2020, 08:10 PM
Dier Mardi Director Sep 29, 2020 Buy $19.00 10,000 190,000 10,000 Sep 29, 2020, 08:09 PM
Morosini Deborah EVP, Chief of Clinical Affairs Sep 29, 2020 Buy $19.00 444 8,436 444 Sep 29, 2020, 08:08 PM
Pierce Christopher EVP and Chief of Business Oper Sep 29, 2020 Buy $19.00 3,750 71,250 3,750 Sep 29, 2020, 08:07 PM
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Buy Sale Option Exercise
Owner Relationship Date Value($)
Combs Andrew EVP, Head of Chemistry 03/31/2022 68,157
Chardonnet Laurent Chief Financial Officer 03/21/2022 48,815
Morosini Deborah EVP, Chief of Clinical Affairs 12/15/2021 336,395
Morosini Deborah EVP, Chief of Clinical Affairs 12/15/2021 373,763
Combs Andrew EVP, Head of Chemistry 12/14/2021 46,400
Combs Andrew EVP, Head of Chemistry 12/13/2021 48,480
Chardonnet Laurent Chief Financial Officer 12/13/2021 61,400
Vaddi Krishna President, CEO 12/13/2021 97,035
Morosini Deborah EVP, Chief of Clinical Affairs 11/16/2021 369,450
Morosini Deborah EVP, Chief of Clinical Affairs 11/16/2021 456,532
Mauro David J Chief Medical Officer 10/05/2021 28,350
Mauro David J Chief Medical Officer 10/05/2021 464,350
Mauro David J Chief Medical Officer 09/07/2021 28,350
Mauro David J Chief Medical Officer 09/07/2021 550,283
Pierce Christopher EVP and Chief of Business Oper 09/02/2021 218,450
Pierce Christopher EVP and Chief of Business Oper 09/02/2021 708,493
Scherle Peggy Chief Scientific Officer 08/26/2021 2,431
Scherle Peggy Chief Scientific Officer 08/27/2021 8,600
Scherle Peggy Chief Scientific Officer 08/27/2021 215,967
Scherle Peggy Chief Scientific Officer 08/26/2021 59,819
Piper Brian Chief Financial Officer 08/25/2021 15,749
Piper Brian Chief Financial Officer 08/25/2021 277,827
Scherle Peggy Chief Scientific Officer 08/13/2021 3,526
Scherle Peggy Chief Scientific Officer 08/13/2021 80,161
Mauro David J Chief Medical Officer 08/05/2021 28,350
Mauro David J Chief Medical Officer 08/05/2021 466,394
Scherle Peggy Chief Scientific Officer 07/27/2021 28,600
Scherle Peggy Chief Scientific Officer 07/27/2021 709,380
Mauro David J Chief Medical Officer 07/06/2021 28,350
Mauro David J Chief Medical Officer 07/06/2021 412,107
Mauro David J Chief Medical Officer 06/07/2021 28,350
Mauro David J Chief Medical Officer 06/07/2021 486,622
Piper Brian Chief Financial Officer 05/25/2021 15,749
Piper Brian Chief Financial Officer 05/25/2021 285,537
Scherle Peggy Chief Scientific Officer 05/07/2021 14,300
Scherle Peggy Chief Scientific Officer 05/07/2021 408,192
Pierce Christopher EVP and Chief of Business Oper 04/29/2021 6,228
Pierce Christopher EVP and Chief of Business Oper 04/29/2021 132,765
Morosini Deborah EVP, Chief of Clinical Affairs 04/29/2021 6,091
Morosini Deborah EVP, Chief of Clinical Affairs 04/29/2021 129,853
Mauro David J Chief Medical Officer 04/19/2021 47,250
Mauro David J Chief Medical Officer 04/19/2021 772,349
Pierce Christopher EVP and Chief of Business Oper 04/08/2021 378
Pierce Christopher EVP and Chief of Business Oper 04/08/2021 8,000
Morosini Deborah EVP, Chief of Clinical Affairs 04/08/2021 189
Morosini Deborah EVP, Chief of Clinical Affairs 04/08/2021 4,000
Mauro David J Chief Medical Officer 04/08/2021 18,176
Mauro David J Chief Medical Officer 04/08/2021 368,852
Scherle Peggy Chief Scientific Officer 04/07/2021 21,979
Scherle Peggy Chief Scientific Officer 04/07/2021 604,144
Pierce Christopher EVP and Chief of Business Oper 04/07/2021 1,565
Pierce Christopher EVP and Chief of Business Oper 04/07/2021 33,188
Morosini Deborah EVP, Chief of Clinical Affairs 04/07/2021 1,890
Morosini Deborah EVP, Chief of Clinical Affairs 04/07/2021 40,043
Mauro David J Chief Medical Officer 04/07/2021 29,074
Mauro David J Chief Medical Officer 04/07/2021 605,023
BAKER BROS. ADVISORS LP Director 01/27/2021 133,332
Bonita David P Director 09/25/2020 23,499,200
BAKER BROS. ADVISORS LP Director 09/29/2020 29,999,993
Combs Andrew EVP, Head of Chemistry 09/29/2020 19,000
ORBIMED ADVISORS LLC Director 09/25/2020 23,499,200
Dier Mardi Director 09/29/2020 190,000
Morosini Deborah EVP, Chief of Clinical Affairs 09/29/2020 8,436
Pierce Christopher EVP and Chief of Business Oper 09/29/2020 71,250
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CHANGE IN SHARES OUTSTANDING
STOCK BUYBACKS
Period of Report
Previous Period
% Change in Shares
10-K/10-Q Filings
Quarter
03/31/2022
12/31/2021
2.21%
1Q
03/31/2022
09/30/2021
2.67%
2Q
03/31/2022
06/30/2021
3.23%
3Q
03/31/2022
03/31/2021
4.31%
4Q
Load More

Period of Report: 03/31/2022

10-K/10-Q Filings: View

Previous Period
% Change in Shares
Quarter
12/31/2021
2.21%
1Q
09/30/2021
2.67%
2Q
06/30/2021
3.23%
3Q
03/31/2021
4.31%
4Q
Load More