Nabriva Therapeutics Plc. (NBRV) NASDAQ
$2.06 -0.10 (-4.63%)
Market Cap: $137.08M
As of 09/29/22 04:00 PM EDT. Market closed.
Nabriva Therapeutics Plc. (NBRV) NASDAQ
$2.06 -0.10 (-4.63%)
Market Cap: $137.08M
As of 09/29/22 04:00 PM EDT. Market closed.
Nabriva Therapeutics is a biopharmaceutical company engaged in the commercialization and development of innovative anti-infective agents to treat serious infections. Nabriva Therapeutics received U.S. Food and Drug Administration approval for XENLETA® (lefamulin injection, lefamulin tablets), the first systemic pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP). Nabriva ... read more
Nabriva Therapeutics is a biopharmaceutical company engaged in the commercialization and development of innovative anti-infective agents to treat serious infections. Nabriva Therapeutics received U.S. Food and Drug Administration approval for XENLETA® (lefamulin injection, lefamulin tablets), the first systemic pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP). Nabriva Therapeutics is also developing CONTEPO™ (fosfomycin) for injection, a potential first-in-class epoxide antibiotic for complicated urinary tract infections (cUTI), including acute pyelonephritis. Nabriva entered into an exclusive agreement with subsidiaries of Merck & Co. Inc., Kenilworth, N.J., USA to market, sell and distribute SIVEXTRO® (tedizolid phosphate) in the United States and certain of its territories. read less
COMPANY PROFILE
Sector
Manufacturing
Industry
Medicinal and Botanical Manufacturing
CEO
Theodore Schroeder
Full Time Employees
72
Sector
Manufacturing
Industry
Medicinal and Botanical Manufacturing
CEO
Theodore Schroeder
Full Time Employees
72
URL
Address
56 Fitzwilliam Square North, DUBLIN.
PRICE CHART
From:
To:
NEWS
KEY STATS
Open
$0
Previous Close
$2.16
Days Range
$2.04 - $2.19
52 week range
$2.04 - $35
Volume
254
Avg. Volume (30 days)
419,731
Market Cap
$137.08M
Dividend Yield
0.00%
P/E
-
Shares Outstanding
66,544,703
Open
$0
Previous Close
$2.16
Days Range
$2.04 - $2.19
52 week range
$2.04 - $35
Volume
254
Avg. Volume (30 days)
419,731
Market Cap
$137.08M
Dividend Yield
0.00%
P/E
-
Shares Outstanding
66,544,703
Open in:
Open in:
INSIDER TRANSACTIONS FOR NABRIVA THERAPEUTICS PLC
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| Schroeder Theodore R | Chief Executive Officer | Sep 06, 2022 | Option Exercise | $0.16 | 225 | 35 | 311,977 | Sep 07, 2022, 06:00 PM |
| Gelone Steven P. | President and COO | Sep 06, 2022 | Option Exercise | $0.16 | 89 | 14 | 361,311 | Sep 07, 2022, 05:57 PM |
| Schroeder Theodore R | Chief Executive Officer | Aug 31, 2022 | Option Exercise | $0.16 | 107 | 18 | 312,202 | Sep 01, 2022, 06:38 PM |
| Gelone Steven P. | President and COO | Aug 31, 2022 | Option Exercise | $0.16 | 61 | 10 | 361,400 | Sep 01, 2022, 06:35 PM |
| Gelone Steven P. | President and COO | Aug 06, 2022 | Option Exercise | $0.18 | 89 | 16 | 361,461 | Aug 08, 2022, 05:45 PM |
| Schroeder Theodore R | Chief Executive Officer | Aug 06, 2022 | Option Exercise | $0.18 | 225 | 42 | 312,309 | Aug 08, 2022, 05:44 PM |
| BURGESS DANIEL D | Director | Aug 02, 2022 | Sale | $0.19 | 11,341 | 2,156 | 10,384 | Aug 04, 2022, 06:24 PM |
| Broom Colin MD | Director | Aug 02, 2022 | Sale | $0.19 | 5,339 | 1,015 | 36,523 | Aug 04, 2022, 06:22 PM |
| Webster Stephen W | Director | Aug 02, 2022 | Sale | $0.19 | 7,826 | 1,487 | 11,447 | Aug 04, 2022, 06:20 PM |
| CORRIGAN MARK | Director | Aug 02, 2022 | Sale | $0.19 | 10,297 | 1,956 | 7,203 | Aug 04, 2022, 06:19 PM |
| Rowland Charles A Jr | Director | Aug 01, 2022 | Sale | $0.17 | 8,496 | 1,487 | 15,277 | Aug 03, 2022, 09:48 PM |
| Bourdow Carrie L. | Director | Aug 01, 2022 | Sale | $0.17 | 8,540 | 1,487 | 9,933 | Aug 03, 2022, 09:47 PM |
| Dalton Lisa | Director | Jul 31, 2022 | Option Exercise | $0.18 | 8,400 | 1,504 | 9,100 | Aug 03, 2022, 09:46 PM |
| Schroeder Theodore R | Chief Executive Officer | Jul 31, 2022 | Option Exercise | $0.18 | 107 | 19 | 312,534 | Aug 03, 2022, 09:45 PM |
| Gelone Steven P. | President and COO | Jul 31, 2022 | Option Exercise | $0.18 | 61 | 11 | 361,550 | Aug 03, 2022, 09:43 PM |
| Schroeder Theodore R | Chief Executive Officer | Jul 06, 2022 | Option Exercise | $0.18 | 225 | 41 | 312,641 | Jul 07, 2022, 04:11 PM |
| Gelone Steven P. | President and COO | Jul 06, 2022 | Option Exercise | $0.18 | 89 | 16 | 361,611 | Jul 07, 2022, 04:10 PM |
| Schroeder Theodore R | Chief Executive Officer | Jun 30, 2022 | Option Exercise | $0.18 | 107 | 19 | 312,866 | Jul 01, 2022, 06:08 PM |
| Gelone Steven P. | President and COO | Jun 30, 2022 | Option Exercise | $0.18 | 61 | 11 | 361,700 | Jul 01, 2022, 06:06 PM |
| Schroeder Theodore R | Chief Executive Officer | Jun 06, 2022 | Option Exercise | $0.20 | 225 | 45 | 312,973 | Jun 07, 2022, 04:47 PM |
| Gelone Steven P. | President and COO | Jun 06, 2022 | Option Exercise | $0.20 | 89 | 18 | 361,761 | Jun 07, 2022, 04:46 PM |
| Schroeder Theodore R | Chief Executive Officer | May 31, 2022 | Option Exercise | $0.21 | 107 | 22 | 313,198 | Jun 02, 2022, 04:10 PM |
| Gelone Steven P. | President and COO | May 31, 2022 | Option Exercise | $0.21 | 61 | 13 | 361,850 | Jun 02, 2022, 04:09 PM |
| Gelone Steven P. | President and COO | May 06, 2022 | Option Exercise | $0.26 | 89 | 23 | 361,911 | May 09, 2022, 06:33 PM |
| Schroeder Theodore R | Chief Executive Officer | May 06, 2022 | Option Exercise | $0.26 | 225 | 58 | 313,305 | May 09, 2022, 06:32 PM |
| Schroeder Theodore R | Chief Executive Officer | Apr 30, 2022 | Option Exercise | $0.31 | 107 | 33 | 313,530 | May 03, 2022, 04:59 PM |
| Gelone Steven P. | President and COO | Apr 30, 2022 | Option Exercise | $0.31 | 61 | 19 | 362,000 | May 03, 2022, 04:58 PM |
| Schroeder Theodore R | Chief Executive Officer | Apr 06, 2022 | Option Exercise | $0.41 | 219 | 90 | 313,637 | Apr 08, 2022, 04:16 PM |
| Gelone Steven P. | President and COO | Apr 06, 2022 | Option Exercise | $0.41 | 89 | 36 | 362,061 | Apr 08, 2022, 04:15 PM |
| Schroeder Theodore R | Chief Executive Officer | Mar 31, 2022 | Option Exercise | $0.42 | 104 | 44 | 313,856 | Apr 04, 2022, 06:27 PM |
| Gelone Steven P. | President and COO | Mar 31, 2022 | Option Exercise | $0.42 | 61 | 26 | 362,150 | Apr 04, 2022, 06:26 PM |
| Gelone Steven P. | President and COO | Mar 06, 2022 | Option Exercise | $0.43 | 89 | 38 | 362,211 | Mar 08, 2022, 04:14 PM |
| Schroeder Theodore R | Chief Executive Officer | Mar 06, 2022 | Option Exercise | $0.43 | 263 | 113 | 313,960 | Mar 08, 2022, 04:12 PM |
| Schroeder Theodore R | Chief Executive Officer | Feb 28, 2022 | Option Exercise | $0.45 | 125 | 56 | 314,223 | Mar 02, 2022, 07:51 PM |
| Gelone Steven P. | President and COO | Feb 28, 2022 | Option Exercise | $0.45 | 61 | 27 | 362,300 | Mar 02, 2022, 07:50 PM |
| Gelone Steven P. | President and COO | Feb 06, 2022 | Option Exercise | $0.48 | 106 | 51 | 362,361 | Feb 08, 2022, 04:26 PM |
| Schroeder Theodore R | Chief Executive Officer | Feb 06, 2022 | Option Exercise | $0.48 | 263 | 126 | 314,348 | Feb 08, 2022, 04:25 PM |
| Schroeder Theodore R | Chief Executive Officer | Jan 31, 2022 | Option Exercise | $0.48 | 125 | 60 | 314,611 | Feb 01, 2022, 08:47 PM |
| Schroeder Theodore R | Chief Executive Officer | Jan 29, 2022 | Option Exercise | $0.45 | 10,766 | 4,845 | 314,736 | Feb 01, 2022, 08:47 PM |
| Gelone Steven P. | President and COO | Jan 31, 2022 | Option Exercise | $0.48 | 73 | 35 | 362,467 | Feb 01, 2022, 08:44 PM |
| Gelone Steven P. | President and COO | Jan 29, 2022 | Option Exercise | $0.45 | 3,483 | 1,567 | 362,540 | Feb 01, 2022, 08:44 PM |
| Schroeder Theodore R | Chief Executive Officer | Jan 06, 2022 | Option Exercise | $0.58 | 270 | 157 | 325,502 | Jan 10, 2022, 04:19 PM |
| Gelone Steven P. | President and COO | Jan 06, 2022 | Option Exercise | $0.58 | 110 | 64 | 366,023 | Jan 10, 2022, 04:18 PM |
| Schroeder Theodore R | Chief Executive Officer | Dec 28, 2021 | Buy | $0.57 | 100,000 | 57,320 | 325,879 | Dec 29, 2021, 09:32 PM |
| Naftzger J. Christopher | General Counsel and Corp Sec | Dec 27, 2021 | Buy | $0.59 | 7,000 | 4,130 | 7,000 | Dec 28, 2021, 07:04 PM |
| Schroeder Theodore R | Chief Executive Officer | Dec 06, 2021 | Option Exercise | $0.72 | 225 | 162 | 225,879 | Dec 08, 2021, 05:14 PM |
| Gelone Steven P. | President and COO | Dec 06, 2021 | Option Exercise | $0.72 | 92 | 66 | 366,196 | Dec 08, 2021, 05:13 PM |
| Schroeder Theodore R | Chief Executive Officer | Nov 30, 2021 | Option Exercise | $0.78 | 107 | 83 | 226,104 | Dec 02, 2021, 06:31 PM |
| Gelone Steven P. | President and COO | Nov 30, 2021 | Option Exercise | $0.78 | 63 | 49 | 366,288 | Dec 02, 2021, 06:28 PM |
| Schroeder Theodore R | Chief Executive Officer | Nov 06, 2021 | Option Exercise | $1.33 | 225 | 299 | 226,211 | Nov 09, 2021, 05:38 PM |
| Gelone Steven P. | President and COO | Nov 06, 2021 | Option Exercise | $1.33 | 92 | 122 | 366,351 | Nov 09, 2021, 05:36 PM |
| Schroeder Theodore R | Chief Executive Officer | Oct 31, 2021 | Option Exercise | $1.15 | 107 | 123 | 226,436 | Nov 01, 2021, 07:51 PM |
| Gelone Steven P. | President and COO | Oct 31, 2021 | Option Exercise | $1.15 | 63 | 72 | 366,443 | Nov 01, 2021, 07:50 PM |
| Gelone Steven P. | President and COO | Oct 06, 2021 | Option Exercise | $1.08 | 92 | 99 | 366,506 | Oct 08, 2021, 04:41 PM |
| Schroeder Theodore R | Chief Executive Officer | Oct 06, 2021 | Option Exercise | $1.08 | 225 | 243 | 226,543 | Oct 08, 2021, 04:39 PM |
| Schroeder Theodore R | Chief Executive Officer | Sep 30, 2021 | Option Exercise | $1.19 | 107 | 127 | 226,768 | Oct 04, 2021, 04:14 PM |
| Gelone Steven P. | President and COO | Sep 30, 2021 | Option Exercise | $1.19 | 63 | 75 | 366,598 | Oct 04, 2021, 04:09 PM |
| Schroeder Theodore R | Chief Executive Officer | Sep 14, 2021 | Buy | $1.13 | 50,000 | 56,500 | 226,875 | Sep 15, 2021, 08:00 PM |
| Schroeder Theodore R | Chief Executive Officer | Sep 06, 2021 | Option Exercise | $1.11 | 225 | 250 | 176,875 | Sep 08, 2021, 05:27 PM |
| Gelone Steven P. | President and COO | Sep 06, 2021 | Option Exercise | $1.11 | 93 | 103 | 366,661 | Sep 08, 2021, 05:25 PM |
| Gelone Steven P. | President and COO | Aug 31, 2021 | Option Exercise | $1.06 | 63 | 67 | 366,754 | Sep 02, 2021, 04:09 PM |
| Schroeder Theodore R | Chief Executive Officer | Aug 31, 2021 | Option Exercise | $1.06 | 107 | 113 | 177,100 | Sep 02, 2021, 04:07 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Aug 31, 2021 | Option Exercise | $1.06 | 37 | 39 | 41,194 | Sep 02, 2021, 04:06 PM |
| Schroeder Theodore R | Chief Executive Officer | Aug 06, 2021 | Option Exercise | $1.17 | 225 | 263 | 177,207 | Aug 10, 2021, 05:16 PM |
| Gelone Steven P. | President and COO | Aug 06, 2021 | Option Exercise | $1.17 | 92 | 108 | 366,817 | Aug 10, 2021, 05:15 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Aug 06, 2021 | Option Exercise | $1.17 | 74 | 87 | 41,231 | Aug 10, 2021, 05:13 PM |
| Webster Stephen W | Director | Aug 02, 2021 | Sale | $1.20 | 777 | 932 | 19,273 | Aug 04, 2021, 09:08 PM |
| BURGESS DANIEL D | Director | Aug 02, 2021 | Sale | $1.20 | 1,125 | 1,350 | 21,725 | Aug 04, 2021, 09:07 PM |
| Broom Colin MD | Director | Aug 02, 2021 | Sale | $1.20 | 531 | 637 | 41,862 | Aug 04, 2021, 09:06 PM |
| Rowland Charles A Jr | Director | Aug 02, 2021 | Sale | $1.20 | 777 | 932 | 23,773 | Aug 04, 2021, 09:05 PM |
| Bourdow Carrie L. | Director | Aug 02, 2021 | Sale | $1.20 | 777 | 932 | 18,473 | Aug 04, 2021, 09:04 PM |
| Schroeder Theodore R | Chief Executive Officer | Jul 31, 2021 | Option Exercise | $1.10 | 107 | 118 | 177,432 | Aug 03, 2021, 04:09 PM |
| Gelone Steven P. | President and COO | Jul 31, 2021 | Option Exercise | $1.10 | 63 | 69 | 366,909 | Aug 03, 2021, 04:07 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Jul 31, 2021 | Option Exercise | $1.10 | 37 | 41 | 41,305 | Aug 03, 2021, 04:06 PM |
| Schroeder Theodore R | Chief Executive Officer | Jul 06, 2021 | Option Exercise | $1.27 | 225 | 286 | 177,539 | Jul 08, 2021, 04:11 PM |
| Gelone Steven P. | President and COO | Jul 06, 2021 | Option Exercise | $1.27 | 92 | 117 | 366,972 | Jul 08, 2021, 04:09 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Jul 06, 2021 | Option Exercise | $1.27 | 74 | 94 | 41,342 | Jul 08, 2021, 04:09 PM |
| Schroeder Theodore R | Chief Executive Officer | Jun 30, 2021 | Option Exercise | $1.35 | 107 | 144 | 177,764 | Jul 02, 2021, 04:06 PM |
| Gelone Steven P. | President and COO | Jun 30, 2021 | Option Exercise | $1.35 | 63 | 85 | 367,064 | Jul 02, 2021, 04:05 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Jun 30, 2021 | Option Exercise | $1.35 | 37 | 50 | 41,416 | Jul 02, 2021, 04:04 PM |
| Gelone Steven P. | President and COO | Jun 06, 2021 | Option Exercise | $1.34 | 92 | 123 | 367,127 | Jun 08, 2021, 04:09 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Jun 06, 2021 | Option Exercise | $1.34 | 73 | 98 | 41,453 | Jun 08, 2021, 04:05 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | May 31, 2021 | Option Exercise | $1.38 | 37 | 51 | 41,526 | Jun 02, 2021, 04:11 PM |
| Schroeder Theodore R | Chief Executive Officer | May 06, 2021 | Option Exercise | $1.49 | 225 | 335 | 178,203 | May 10, 2021, 05:53 PM |
| Gelone Steven P. | President and COO | May 06, 2021 | Option Exercise | $1.49 | 92 | 137 | 367,282 | May 10, 2021, 05:52 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | May 06, 2021 | Option Exercise | $1.49 | 74 | 110 | 41,563 | May 10, 2021, 05:51 PM |
| Gelone Steven P. | President and COO | Apr 30, 2021 | Option Exercise | $1.78 | 63 | 112 | 367,374 | May 04, 2021, 04:04 PM |
| Schroeder Theodore R | Chief Executive Officer | Apr 30, 2021 | Option Exercise | $1.78 | 107 | 190 | 178,428 | May 04, 2021, 04:03 PM |
| Schroeder Theodore R | Chief Executive Officer | Feb 06, 2021 | Option Exercise | $2.90 | 2,695 | 7,816 | 178,985 | Apr 08, 2021, 09:48 PM |
| Schroeder Theodore R | Chief Executive Officer | Apr 06, 2021 | Option Exercise | $1.73 | 225 | 389 | 178,535 | Apr 08, 2021, 09:48 PM |
| Schroeder Theodore R | Chief Executive Officer | Mar 06, 2021 | Option Exercise | $1.79 | 225 | 403 | 178,760 | Apr 08, 2021, 09:48 PM |
| Gelone Steven P. | President and COO | Apr 06, 2021 | Option Exercise | $1.73 | 92 | 159 | 76,740 | Apr 08, 2021, 09:47 PM |
| Gelone Steven P. | President and COO | Mar 06, 2021 | Option Exercise | $1.79 | 92 | 165 | 76,832 | Apr 08, 2021, 09:47 PM |
| Gelone Steven P. | President and COO | Feb 06, 2021 | Option Exercise | $2.90 | 1,104 | 3,202 | 76,924 | Apr 08, 2021, 09:47 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Mar 06, 2021 | Option Exercise | $1.79 | 71 | 127 | 41,748 | Apr 08, 2021, 09:46 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Feb 06, 2021 | Option Exercise | $2.90 | 870 | 2,523 | 41,819 | Apr 08, 2021, 09:46 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Apr 06, 2021 | Option Exercise | $1.73 | 74 | 128 | 41,674 | Apr 08, 2021, 09:46 PM |
| Gelone Steven P. | President and COO | Mar 31, 2021 | Option Exercise | $1.66 | 63 | 105 | 78,028 | Apr 02, 2021, 06:14 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Mar 31, 2021 | Option Exercise | $1.66 | 37 | 61 | 42,689 | Apr 02, 2021, 06:12 PM |
| Sender Gary | Chief Financial Officer | Feb 28, 2021 | Option Exercise | $2.39 | 31 | 74 | 20,472 | Mar 02, 2021, 07:43 PM |
| Schroeder Theodore R | Chief Executive Officer | Feb 28, 2021 | Option Exercise | $2.39 | 106 | 253 | 181,787 | Mar 02, 2021, 07:42 PM |
| Schranz Jennifer | Chief Medical Officer | Feb 28, 2021 | Option Exercise | $2.39 | 33 | 79 | 39,125 | Mar 02, 2021, 07:40 PM |
| Gelone Steven P. | President and COO | Feb 28, 2021 | Option Exercise | $2.39 | 63 | 151 | 78,091 | Mar 02, 2021, 07:39 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Feb 28, 2021 | Option Exercise | $2.39 | 38 | 91 | 42,726 | Mar 02, 2021, 07:37 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Jan 31, 2021 | Option Exercise | $2.62 | 43 | 113 | 42,764 | Feb 02, 2021, 08:06 PM |
| Sender Gary | Chief Financial Officer | Jan 31, 2021 | Option Exercise | $2.62 | 37 | 97 | 20,503 | Feb 02, 2021, 08:01 PM |
| Schroeder Theodore R | Chief Executive Officer | Jan 31, 2021 | Option Exercise | $2.62 | 125 | 327 | 181,893 | Feb 02, 2021, 08:01 PM |
| Schranz Jennifer | Chief Medical Officer | Jan 31, 2021 | Option Exercise | $2.62 | 36 | 94 | 39,158 | Feb 02, 2021, 08:00 PM |
| Gelone Steven P. | President and COO | Jan 31, 2021 | Option Exercise | $2.62 | 75 | 196 | 78,154 | Feb 02, 2021, 07:57 PM |
| Sender Gary | Chief Financial Officer | Dec 31, 2020 | Option Exercise | $2.42 | 32 | 77 | 20,540 | Jan 05, 2021, 05:16 PM |
| Schroeder Theodore R | Chief Executive Officer | Dec 31, 2020 | Option Exercise | $2.42 | 121 | 293 | 64,518 | Jan 05, 2021, 05:15 PM |
| Gelone Steven P. | President and COO | Dec 31, 2020 | Option Exercise | $2.42 | 63 | 152 | 35,729 | Jan 05, 2021, 05:13 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Dec 31, 2020 | Option Exercise | $2.42 | 37 | 90 | 20,307 | Jan 05, 2021, 05:12 PM |
| Schranz Jennifer | Chief Medical Officer | Dec 31, 2020 | Option Exercise | $2.42 | 30 | 73 | 16,694 | Jan 05, 2021, 12:00 AM |
| Sender Gary | Chief Financial Officer | Nov 30, 2020 | Option Exercise | $0.43 | 312 | 133 | 205,728 | Dec 01, 2020, 08:22 PM |
| Schroeder Theodore R | Chief Executive Officer | Nov 30, 2020 | Option Exercise | $0.43 | 1,211 | 517 | 646,396 | Dec 01, 2020, 08:21 PM |
| Schranz Jennifer | Chief Medical Officer | Nov 30, 2020 | Option Exercise | $0.43 | 301 | 129 | 167,240 | Dec 01, 2020, 08:21 PM |
| Gelone Steven P. | President and COO | Nov 30, 2020 | Option Exercise | $0.43 | 628 | 268 | 357,926 | Dec 01, 2020, 08:20 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Nov 30, 2020 | Option Exercise | $0.43 | 368 | 157 | 203,444 | Dec 01, 2020, 08:20 PM |
| Sender Gary | Chief Financial Officer | Oct 31, 2020 | Option Exercise | $0.50 | 312 | 155 | 206,040 | Nov 02, 2020, 07:07 PM |
| Schroeder Theodore R | Chief Executive Officer | Oct 31, 2020 | Option Exercise | $0.50 | 1,211 | 600 | 647,607 | Nov 02, 2020, 07:07 PM |
| Schranz Jennifer | Chief Medical Officer | Oct 31, 2020 | Option Exercise | $0.50 | 301 | 149 | 167,541 | Nov 02, 2020, 07:07 PM |
| Gelone Steven P. | President and COO | Oct 31, 2020 | Option Exercise | $0.50 | 628 | 311 | 358,554 | Nov 02, 2020, 07:06 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Oct 31, 2020 | Option Exercise | $0.50 | 366 | 181 | 203,812 | Nov 02, 2020, 07:06 PM |
| Sender Gary | Chief Financial Officer | Sep 30, 2020 | Option Exercise | $0.53 | 312 | 166 | 206,352 | Oct 01, 2020, 04:32 PM |
| Schroeder Theodore R | Chief Executive Officer | Sep 30, 2020 | Option Exercise | $0.53 | 1,211 | 645 | 648,818 | Oct 01, 2020, 04:32 PM |
| Schranz Jennifer | Chief Medical Officer | Sep 30, 2020 | Option Exercise | $0.53 | 301 | 160 | 167,842 | Oct 01, 2020, 04:31 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Sep 30, 2020 | Option Exercise | $0.53 | 366 | 195 | 185,393 | Oct 01, 2020, 04:30 PM |
| Gelone Steven P. | President and COO | Sep 30, 2020 | Option Exercise | $0.53 | 628 | 335 | 359,182 | Oct 01, 2020, 04:30 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Sep 30, 2020 | Option Exercise | $0.53 | 366 | 195 | 204,178 | Oct 01, 2020, 04:30 PM |
| Sender Gary | Chief Financial Officer | Aug 31, 2020 | Option Exercise | $0.62 | 312 | 193 | 206,664 | Sep 02, 2020, 05:16 PM |
| Gelone Steven P. | President and COO | Aug 31, 2020 | Option Exercise | $0.62 | 628 | 389 | 359,810 | Sep 02, 2020, 05:15 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Aug 31, 2020 | Option Exercise | $0.62 | 366 | 227 | 185,759 | Sep 02, 2020, 05:15 PM |
| Schranz Jennifer | Chief Medical Officer | Aug 31, 2020 | Option Exercise | $0.62 | 301 | 186 | 168,143 | Sep 02, 2020, 05:15 PM |
| Schroeder Theodore R | Chief Executive Officer | Aug 31, 2020 | Option Exercise | $0.62 | 1,211 | 750 | 650,029 | Sep 02, 2020, 05:15 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Aug 31, 2020 | Option Exercise | $0.62 | 366 | 227 | 204,544 | Sep 02, 2020, 05:14 PM |
| Gelone Steven P. | President and COO | Aug 20, 2020 | Option Exercise | $0.65 | 7,761 | 5,026 | 364,995 | Aug 21, 2020, 07:04 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Aug 20, 2020 | Option Exercise | $0.65 | 3,759 | 2,434 | 186,125 | Aug 21, 2020, 07:03 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Aug 20, 2020 | Option Exercise | $0.65 | 3,759 | 2,434 | 204,910 | Aug 21, 2020, 07:03 PM |
| Broom Colin MD | Director | Aug 20, 2020 | Sale | $0.65 | 11,064 | 7,165 | 248,936 | Aug 21, 2020, 07:02 PM |
| Sender Gary | Chief Financial Officer | Aug 20, 2020 | Option Exercise | $0.65 | 3,204 | 2,075 | 206,976 | Aug 21, 2020, 07:02 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Jul 31, 2020 | Option Exercise | $0.76 | 366 | 278 | 197,419 | Aug 04, 2020, 04:57 PM |
| Gelone Steven P. | President and COO | Jul 31, 2020 | Option Exercise | $0.76 | 628 | 477 | 340,949 | Aug 04, 2020, 04:56 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Jul 31, 2020 | Option Exercise | $0.76 | 366 | 278 | 178,634 | Aug 04, 2020, 04:09 PM |
| Schranz Jennifer | Chief Medical Officer | Jul 31, 2020 | Option Exercise | $0.76 | 301 | 229 | 168,444 | Aug 04, 2020, 04:08 PM |
| Schroeder Theodore R | Chief Executive Officer | Jul 31, 2020 | Option Exercise | $0.76 | 1,211 | 920 | 651,240 | Aug 04, 2020, 04:08 PM |
| Sender Gary | Chief Financial Officer | Jul 31, 2020 | Option Exercise | $0.76 | 312 | 237 | 198,930 | Aug 04, 2020, 04:07 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Jun 30, 2020 | Option Exercise | $0.67 | 366 | 247 | 179,000 | Jul 02, 2020, 04:07 PM |
| Schranz Jennifer | Chief Medical Officer | Jun 30, 2020 | Option Exercise | $0.67 | 301 | 203 | 168,745 | Jul 02, 2020, 04:07 PM |
| Schroeder Theodore R | Chief Executive Officer | Jun 30, 2020 | Option Exercise | $0.67 | 1,211 | 817 | 652,451 | Jul 02, 2020, 04:06 PM |
| Sender Gary | Chief Financial Officer | Jun 30, 2020 | Option Exercise | $0.67 | 312 | 210 | 199,242 | Jul 02, 2020, 04:06 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Jun 30, 2020 | Option Exercise | $0.67 | 366 | 247 | 197,785 | Jul 02, 2020, 12:00 AM |
| Gelone Steven P. | President and COO | Jun 30, 2020 | Option Exercise | $0.67 | 628 | 424 | 341,577 | Jul 02, 2020, 12:00 AM |
| Sender Gary | Chief Financial Officer | May 31, 2020 | Option Exercise | $1.14 | 312 | 356 | 199,554 | Jun 03, 2020, 06:08 AM |
| Gelone Steven P. | President and COO | May 31, 2020 | Option Exercise | $1.14 | 628 | 716 | 342,205 | Jun 03, 2020, 06:07 AM |
| Schroeder Theodore R | Chief Executive Officer | May 31, 2020 | Option Exercise | $1.14 | 1,211 | 1,381 | 653,662 | Jun 03, 2020, 06:07 AM |
| Schranz Jennifer | Chief Medical Officer | May 31, 2020 | Option Exercise | $1.14 | 301 | 343 | 169,046 | Jun 03, 2020, 06:06 AM |
| Lavino Francesco Maria | Chief Commercial Officer | May 31, 2020 | Option Exercise | $1.14 | 366 | 417 | 179,366 | Jun 03, 2020, 06:06 AM |
| Crotty Robert | Gen Counsel & Corp Secretary | May 31, 2020 | Option Exercise | $1.14 | 366 | 417 | 198,151 | Jun 03, 2020, 06:05 AM |
| Crotty Robert | Gen Counsel & Corp Secretary | Apr 30, 2020 | Option Exercise | $0.55 | 366 | 201 | 198,517 | May 04, 2020, 06:33 PM |
| Sender Gary | Chief Financial Officer | Apr 30, 2020 | Option Exercise | $0.55 | 301 | 165 | 193,679 | May 04, 2020, 06:32 PM |
| Schranz Jennifer | Chief Medical Officer | Apr 30, 2020 | Option Exercise | $0.55 | 301 | 165 | 169,347 | May 04, 2020, 06:32 PM |
| Schroeder Theodore R | Chief Executive Officer | Apr 30, 2020 | Option Exercise | $0.55 | 1,211 | 664 | 648,686 | May 04, 2020, 06:31 PM |
| Gelone Steven P. | President and COO | Apr 30, 2020 | Option Exercise | $0.55 | 606 | 332 | 336,646 | May 04, 2020, 06:31 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Apr 30, 2020 | Option Exercise | $0.55 | 366 | 201 | 179,732 | May 04, 2020, 06:30 PM |
| Gelone Steven P. | President and COO | Mar 31, 2020 | Option Exercise | $0.57 | 606 | 348 | 337,252 | Apr 02, 2020, 05:49 PM |
| Sender Gary | Chief Financial Officer | Mar 31, 2020 | Option Exercise | $0.57 | 301 | 173 | 193,980 | Apr 02, 2020, 05:49 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Mar 31, 2020 | Option Exercise | $0.57 | 366 | 210 | 180,098 | Apr 02, 2020, 05:49 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Mar 31, 2020 | Option Exercise | $0.57 | 366 | 210 | 198,883 | Apr 02, 2020, 05:48 PM |
| Schroeder Theodore R | Chief Executive Officer | Mar 31, 2020 | Option Exercise | $0.57 | 1,211 | 696 | 649,897 | Apr 02, 2020, 05:48 PM |
| Schranz Jennifer | Chief Medical Officer | Mar 31, 2020 | Option Exercise | $0.57 | 301 | 173 | 169,648 | Apr 02, 2020, 05:47 PM |
| Schroeder Theodore R | Chief Executive Officer | Feb 28, 2020 | Option Exercise | $1.35 | 1,211 | 1,635 | 651,108 | Mar 03, 2020, 09:32 PM |
| Gelone Steven P. | President & COO | Feb 28, 2020 | Option Exercise | $1.35 | 606 | 818 | 337,858 | Mar 03, 2020, 09:32 PM |
| Sender Gary | Chief Financial Officer | Feb 28, 2020 | Option Exercise | $1.35 | 301 | 406 | 194,281 | Mar 03, 2020, 09:32 PM |
| Schranz Jennifer | Chief Medical Officer | Feb 28, 2020 | Option Exercise | $1.35 | 301 | 406 | 169,949 | Mar 03, 2020, 09:31 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Feb 28, 2020 | Option Exercise | $1.35 | 366 | 494 | 180,464 | Mar 03, 2020, 09:31 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Feb 28, 2020 | Option Exercise | $1.35 | 366 | 494 | 199,276 | Mar 03, 2020, 09:31 PM |
| Schranz Jennifer | Chief Medical Officer | Jan 31, 2020 | Option Exercise | $1.35 | 4,295 | 5,798 | 53,705 | Feb 04, 2020, 08:56 PM |
| Gelone Steven P. | President & COO | Jan 31, 2020 | Option Exercise | $1.35 | 8,651 | 11,679 | 171,919 | Feb 04, 2020, 08:56 PM |
| Sender Gary | Chief Financial Officer | Jan 31, 2020 | Option Exercise | $1.35 | 4,295 | 5,798 | 78,669 | Feb 04, 2020, 08:56 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Jan 31, 2020 | Option Exercise | $1.35 | 3,892 | 5,254 | 75,830 | Feb 04, 2020, 08:55 PM |
| Schroeder Theodore R | Chief Executive Officer | Jan 31, 2020 | Option Exercise | $1.35 | 16,276 | 21,973 | 302,760 | Feb 04, 2020, 08:55 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Jan 31, 2020 | Option Exercise | $1.35 | 3,892 | 5,254 | 83,097 | Feb 04, 2020, 08:55 PM |
| Broom Colin MD | Director | Aug 30, 2019 | Buy | $2.03 | 10,177 | 20,668 | 208,750 | Sep 03, 2019, 04:04 PM |
| Schroeder Theodore R | Chief Executive Officer | Aug 27, 2019 | Buy | $1.79 | 50,000 | 89,500 | 117,489 | Aug 28, 2019, 04:01 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Aug 22, 2019 | Buy | $2.04 | 4,800 | 9,780 | 15,972 | Aug 26, 2019, 09:49 PM |
| Broom Colin MD | Director | Aug 21, 2019 | Sale | $2.07 | 10,177 | 21,066 | 125,724 | Aug 26, 2019, 09:36 PM |
| Gelone Steven P. | President & COO | Aug 21, 2019 | Sale | $2.08 | 8,206 | 17,068 | 52,386 | Aug 26, 2019, 09:35 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Aug 21, 2019 | Sale | $2.08 | 3,797 | 7,898 | 23,239 | Aug 26, 2019, 09:35 PM |
| Sender Gary | Chief Financial Officer | Aug 21, 2019 | Sale | $2.08 | 3,390 | 7,051 | 19,214 | Aug 26, 2019, 09:35 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Aug 21, 2019 | Sale | $2.08 | 3,797 | 7,898 | 11,172 | Aug 26, 2019, 09:34 PM |
| Sender Gary | Chief Financial Officer | Aug 21, 2019 | Option Exercise | $2.08 | 3,390 | 7,051 | 19,214 | Aug 21, 2019, 09:22 PM |
| Broom Colin MD | Director | Aug 21, 2019 | Option Exercise | $2.07 | 10,177 | 21,066 | 125,724 | Aug 21, 2019, 09:22 PM |
| Crotty Robert | Gen Counsel & Corp Secretary | Aug 21, 2019 | Option Exercise | $2.08 | 3,797 | 7,898 | 23,239 | Aug 21, 2019, 09:22 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Aug 21, 2019 | Option Exercise | $2.08 | 3,797 | 7,898 | 11,172 | Aug 21, 2019, 09:21 PM |
| Gelone Steven P. | President and COO | Aug 21, 2019 | Option Exercise | $2.08 | 8,206 | 17,068 | 52,386 | Aug 21, 2019, 09:21 PM |
| Rowland Charles A Jr | Director | Dec 24, 2018 | Buy | $1.31 | 53,000 | 69,430 | 53,000 | Dec 27, 2018, 04:05 PM |
| Talbot George Harrison | Director | Jul 31, 2018 | Buy | $2.75 | 14,500 | 39,875 | 47,640 | Aug 02, 2018, 05:52 PM |
| BURGESS DANIEL D | Director | Jul 31, 2018 | Buy | $2.75 | 36,000 | 99,000 | 36,000 | Aug 02, 2018, 05:51 PM |
| Gelone Steven P. | Chief Scientific Officer | Jun 23, 2018 | Buy | $3.82 | 10,000 | 38,200 | 22,740 | Jun 26, 2018, 09:09 AM |
| Schranz Jennifer | Chief Medical Officer | Jun 22, 2018 | Buy | $3.73 | 5,500 | 20,515 | 5,500 | Jun 25, 2018, 09:47 AM |
| Broom Colin MD | CEO & Director | Jun 22, 2018 | Buy | $3.72 | 5,000 | 18,600 | 102,151 | Jun 25, 2018, 09:47 AM |
| Lavino Francesco Maria | Chief Commercial Officer | May 23, 2018 | Buy | $4.60 | 2,160 | 9,936 | 3,719 | May 29, 2018, 01:48 PM |
| Sender Gary | Chief Financial Officer | May 23, 2018 | Buy | $4.57 | 2,000 | 9,140 | 6,200 | May 23, 2018, 08:38 PM |
| Webster Stephen W | Director | May 23, 2018 | Buy | $4.59 | 8,000 | 36,720 | 8,000 | May 23, 2018, 08:37 PM |
| Broom Colin MD | CEO & Director | May 23, 2018 | Buy | $4.60 | 10,000 | 46,000 | 97,151 | May 23, 2018, 08:36 PM |
| Crotty Robert | General Counsel & Secretary | May 23, 2018 | Buy | $4.48 | 10,000 | 44,800 | 10,000 | May 23, 2018, 12:29 PM |
| Lavino Francesco Maria | Chief Commercial Officer | Nov 29, 2017 | Buy | $6.29 | 1,569 | 9,869 | 1,569 | Dec 01, 2017, 04:07 PM |
| Sender Gary | Chief Financial Officer | Sep 22, 2017 | Buy | $8.21 | 2,000 | 16,420 | 4,200 | Sep 26, 2017, 05:01 PM |
| Broom Colin MD | Chief Executive Officer | Sep 22, 2017 | Buy | $8.35 | 2,588 | 21,610 | 87,151 | Sep 26, 2017, 05:01 PM |
| Vivo Capital VIII, LLC | 10% Owner | Sep 18, 2017 | Buy | $9.46 | 6,386 | 60,412 | 494,329 | Sep 18, 2017, 09:13 PM |
| Vivo Capital VIII, LLC | 10% Owner | Sep 18, 2017 | Buy | $9.46 | 46,245 | 437,478 | 3,579,861 | Sep 18, 2017, 09:13 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Sep 13, 2017 | Sale | $8.54 | 22,721 | 193,956 | 2,337,557 | Sep 14, 2017, 08:21 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Sep 12, 2017 | Sale | $8.63 | 10,458 | 90,236 | 2,360,278 | Sep 14, 2017, 08:21 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Sep 14, 2017 | Sale | $8.52 | 3,429 | 29,224 | 2,334,128 | Sep 14, 2017, 08:21 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Aug 31, 2017 | Sale | $9.50 | 639 | 6,071 | 2,370,735 | Sep 05, 2017, 08:18 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Aug 08, 2017 | Sale | $10.50 | 2,013 | 21,137 | 2,371,374 | Aug 09, 2017, 08:54 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Aug 07, 2017 | Sale | $10.50 | 17,790 | 186,795 | 2,373,387 | Aug 09, 2017, 08:54 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Jul 28, 2017 | Sale | $10.51 | 6,585 | 69,195 | 2,391,177 | Aug 01, 2017, 09:21 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Jul 24, 2017 | Sale | $10.50 | 160 | 1,680 | 2,397,762 | Jul 26, 2017, 09:03 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Jul 20, 2017 | Sale | $10.50 | 23,445 | 246,173 | 2,397,922 | Jul 24, 2017, 09:10 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Jul 19, 2017 | Sale | $10.50 | 20,786 | 218,253 | 2,421,367 | Jul 24, 2017, 09:10 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Jun 30, 2017 | Sale | $10.94 | 1,775 | 19,420 | 2,583,229 | Jul 05, 2017, 08:58 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Jul 03, 2017 | Sale | $10.95 | 11,352 | 124,250 | 2,571,877 | Jul 05, 2017, 08:58 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Jun 29, 2017 | Sale | $10.72 | 1,603 | 17,189 | 2,585,004 | Jun 29, 2017, 09:33 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Jun 28, 2017 | Sale | $11.10 | 4,789 | 53,158 | 2,586,697 | Jun 29, 2017, 09:33 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Jun 27, 2017 | Sale | $10.83 | 2,166 | 23,457 | 2,591,396 | Jun 29, 2017, 09:33 PM |
| Talbot George Harrison | Director | Jun 15, 2017 | Sale | $94.10 | 100 | 9,410 | 3,249 | Jun 19, 2017, 06:14 PM |
| Talbot George Harrison | Director | Jun 19, 2017 | Sale | $91.00 | 46 | 4,186 | 3,179 | Jun 19, 2017, 06:14 PM |
| Talbot George Harrison | Director | Jun 16, 2017 | Sale | $93.50 | 24 | 2,244 | 3,225 | Jun 19, 2017, 06:14 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Jun 01, 2017 | Sale | $11.27 | 400 | 4,508 | 2,593,562 | Jun 05, 2017, 09:41 PM |
| Talbot George Harrison | Director | May 30, 2017 | Sale | $101.26 | 210 | 21,265 | 3,449 | Jun 01, 2017, 08:49 PM |
| Talbot George Harrison | Director | May 25, 2017 | Sale | $100.65 | 295 | 29,693 | 3,649 | May 25, 2017, 08:58 PM |
| Talbot George Harrison | Director | May 23, 2017 | Sale | $99.70 | 30 | 2,991 | 3,854 | May 25, 2017, 08:58 PM |
| Talbot George Harrison | Director | May 16, 2017 | Sale | $102.76 | 150 | 15,413 | 3,984 | May 17, 2017, 07:01 PM |
| Talbot George Harrison | Director | May 15, 2017 | Sale | $101.50 | 50 | 5,075 | 4,034 | May 17, 2017, 07:01 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 28, 2017 | Sale | $11.03 | 15,130 | 166,813 | 2,593,962 | Apr 28, 2017, 07:13 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 27, 2017 | Sale | $11.00 | 100 | 1,100 | 2,609,092 | Apr 28, 2017, 07:13 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 26, 2017 | Sale | $11.00 | 709 | 7,799 | 2,609,192 | Apr 28, 2017, 07:13 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 21, 2017 | Sale | $11.04 | 2,622 | 28,937 | 2,609,901 | Apr 25, 2017, 07:19 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 20, 2017 | Sale | $11.00 | 325 | 3,575 | 2,612,523 | Apr 20, 2017, 08:29 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 19, 2017 | Sale | $11.07 | 11,785 | 130,434 | 2,612,848 | Apr 20, 2017, 08:29 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 18, 2017 | Sale | $11.16 | 11,822 | 131,880 | 2,624,633 | Apr 20, 2017, 08:29 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 11, 2017 | Sale | $11.40 | 8,597 | 98,034 | 2,660,689 | Apr 13, 2017, 09:12 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 13, 2017 | Sale | $11.13 | 10,984 | 122,232 | 2,636,455 | Apr 13, 2017, 09:12 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 12, 2017 | Sale | $11.22 | 13,250 | 148,653 | 2,647,439 | Apr 13, 2017, 09:12 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 10, 2017 | Sale | $10.73 | 37,876 | 406,451 | 2,669,286 | Apr 11, 2017, 06:04 AM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 07, 2017 | Sale | $10.97 | 21,501 | 235,931 | 2,725,163 | Apr 11, 2017, 06:04 AM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 06, 2017 | Sale | $11.22 | 31,217 | 350,160 | 2,753,263 | Apr 11, 2017, 06:04 AM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 07, 2017 | Sale | $10.97 | 21,501 | 235,931 | 241,271 | Apr 10, 2017, 09:38 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 06, 2017 | Sale | $11.22 | 31,217 | 350,160 | 269,371 | Apr 10, 2017, 09:38 PM |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | Apr 10, 2017 | Sale | $10.73 | 37,876 | 406,451 | 185,394 | Apr 10, 2017, 09:38 PM |
Load More Insider Transactions
Buy
Sale
Option Exercise
| Owner | Relationship | Date | Value($) |
| Schroeder Theodore R | Chief Executive Officer | 09/06/2022 | 35 |
| Gelone Steven P. | President and COO | 09/06/2022 | 14 |
| Schroeder Theodore R | Chief Executive Officer | 08/31/2022 | 18 |
| Gelone Steven P. | President and COO | 08/31/2022 | 10 |
| Gelone Steven P. | President and COO | 08/06/2022 | 16 |
| Schroeder Theodore R | Chief Executive Officer | 08/06/2022 | 42 |
| BURGESS DANIEL D | Director | 08/02/2022 | 2,156 |
| Broom Colin MD | Director | 08/02/2022 | 1,015 |
| Webster Stephen W | Director | 08/02/2022 | 1,487 |
| CORRIGAN MARK | Director | 08/02/2022 | 1,956 |
| Rowland Charles A Jr | Director | 08/01/2022 | 1,487 |
| Bourdow Carrie L. | Director | 08/01/2022 | 1,487 |
| Dalton Lisa | Director | 07/31/2022 | 1,504 |
| Schroeder Theodore R | Chief Executive Officer | 07/31/2022 | 19 |
| Gelone Steven P. | President and COO | 07/31/2022 | 11 |
| Schroeder Theodore R | Chief Executive Officer | 07/06/2022 | 41 |
| Gelone Steven P. | President and COO | 07/06/2022 | 16 |
| Schroeder Theodore R | Chief Executive Officer | 06/30/2022 | 19 |
| Gelone Steven P. | President and COO | 06/30/2022 | 11 |
| Schroeder Theodore R | Chief Executive Officer | 06/06/2022 | 45 |
| Gelone Steven P. | President and COO | 06/06/2022 | 18 |
| Schroeder Theodore R | Chief Executive Officer | 05/31/2022 | 22 |
| Gelone Steven P. | President and COO | 05/31/2022 | 13 |
| Gelone Steven P. | President and COO | 05/06/2022 | 23 |
| Schroeder Theodore R | Chief Executive Officer | 05/06/2022 | 58 |
| Schroeder Theodore R | Chief Executive Officer | 04/30/2022 | 33 |
| Gelone Steven P. | President and COO | 04/30/2022 | 19 |
| Schroeder Theodore R | Chief Executive Officer | 04/06/2022 | 90 |
| Gelone Steven P. | President and COO | 04/06/2022 | 36 |
| Schroeder Theodore R | Chief Executive Officer | 03/31/2022 | 44 |
| Gelone Steven P. | President and COO | 03/31/2022 | 26 |
| Gelone Steven P. | President and COO | 03/06/2022 | 38 |
| Schroeder Theodore R | Chief Executive Officer | 03/06/2022 | 113 |
| Schroeder Theodore R | Chief Executive Officer | 02/28/2022 | 56 |
| Gelone Steven P. | President and COO | 02/28/2022 | 27 |
| Gelone Steven P. | President and COO | 02/06/2022 | 51 |
| Schroeder Theodore R | Chief Executive Officer | 02/06/2022 | 126 |
| Schroeder Theodore R | Chief Executive Officer | 01/31/2022 | 60 |
| Schroeder Theodore R | Chief Executive Officer | 01/29/2022 | 4,845 |
| Gelone Steven P. | President and COO | 01/31/2022 | 35 |
| Gelone Steven P. | President and COO | 01/29/2022 | 1,567 |
| Schroeder Theodore R | Chief Executive Officer | 01/06/2022 | 157 |
| Gelone Steven P. | President and COO | 01/06/2022 | 64 |
| Schroeder Theodore R | Chief Executive Officer | 12/28/2021 | 57,320 |
| Naftzger J. Christopher | General Counsel and Corp Sec | 12/27/2021 | 4,130 |
| Schroeder Theodore R | Chief Executive Officer | 12/06/2021 | 162 |
| Gelone Steven P. | President and COO | 12/06/2021 | 66 |
| Schroeder Theodore R | Chief Executive Officer | 11/30/2021 | 83 |
| Gelone Steven P. | President and COO | 11/30/2021 | 49 |
| Schroeder Theodore R | Chief Executive Officer | 11/06/2021 | 299 |
| Gelone Steven P. | President and COO | 11/06/2021 | 122 |
| Schroeder Theodore R | Chief Executive Officer | 10/31/2021 | 123 |
| Gelone Steven P. | President and COO | 10/31/2021 | 72 |
| Gelone Steven P. | President and COO | 10/06/2021 | 99 |
| Schroeder Theodore R | Chief Executive Officer | 10/06/2021 | 243 |
| Schroeder Theodore R | Chief Executive Officer | 09/30/2021 | 127 |
| Gelone Steven P. | President and COO | 09/30/2021 | 75 |
| Schroeder Theodore R | Chief Executive Officer | 09/14/2021 | 56,500 |
| Schroeder Theodore R | Chief Executive Officer | 09/06/2021 | 250 |
| Gelone Steven P. | President and COO | 09/06/2021 | 103 |
| Gelone Steven P. | President and COO | 08/31/2021 | 67 |
| Schroeder Theodore R | Chief Executive Officer | 08/31/2021 | 113 |
| Crotty Robert | Gen Counsel & Corp Secretary | 08/31/2021 | 39 |
| Schroeder Theodore R | Chief Executive Officer | 08/06/2021 | 263 |
| Gelone Steven P. | President and COO | 08/06/2021 | 108 |
| Crotty Robert | Gen Counsel & Corp Secretary | 08/06/2021 | 87 |
| Webster Stephen W | Director | 08/02/2021 | 932 |
| BURGESS DANIEL D | Director | 08/02/2021 | 1,350 |
| Broom Colin MD | Director | 08/02/2021 | 637 |
| Rowland Charles A Jr | Director | 08/02/2021 | 932 |
| Bourdow Carrie L. | Director | 08/02/2021 | 932 |
| Schroeder Theodore R | Chief Executive Officer | 07/31/2021 | 118 |
| Gelone Steven P. | President and COO | 07/31/2021 | 69 |
| Crotty Robert | Gen Counsel & Corp Secretary | 07/31/2021 | 41 |
| Schroeder Theodore R | Chief Executive Officer | 07/06/2021 | 286 |
| Gelone Steven P. | President and COO | 07/06/2021 | 117 |
| Crotty Robert | Gen Counsel & Corp Secretary | 07/06/2021 | 94 |
| Schroeder Theodore R | Chief Executive Officer | 06/30/2021 | 144 |
| Gelone Steven P. | President and COO | 06/30/2021 | 85 |
| Crotty Robert | Gen Counsel & Corp Secretary | 06/30/2021 | 50 |
| Gelone Steven P. | President and COO | 06/06/2021 | 123 |
| Crotty Robert | Gen Counsel & Corp Secretary | 06/06/2021 | 98 |
| Crotty Robert | Gen Counsel & Corp Secretary | 05/31/2021 | 51 |
| Schroeder Theodore R | Chief Executive Officer | 05/06/2021 | 335 |
| Gelone Steven P. | President and COO | 05/06/2021 | 137 |
| Crotty Robert | Gen Counsel & Corp Secretary | 05/06/2021 | 110 |
| Gelone Steven P. | President and COO | 04/30/2021 | 112 |
| Schroeder Theodore R | Chief Executive Officer | 04/30/2021 | 190 |
| Schroeder Theodore R | Chief Executive Officer | 02/06/2021 | 7,816 |
| Schroeder Theodore R | Chief Executive Officer | 04/06/2021 | 389 |
| Schroeder Theodore R | Chief Executive Officer | 03/06/2021 | 403 |
| Gelone Steven P. | President and COO | 04/06/2021 | 159 |
| Gelone Steven P. | President and COO | 03/06/2021 | 165 |
| Gelone Steven P. | President and COO | 02/06/2021 | 3,202 |
| Crotty Robert | Gen Counsel & Corp Secretary | 03/06/2021 | 127 |
| Crotty Robert | Gen Counsel & Corp Secretary | 02/06/2021 | 2,523 |
| Crotty Robert | Gen Counsel & Corp Secretary | 04/06/2021 | 128 |
| Gelone Steven P. | President and COO | 03/31/2021 | 105 |
| Crotty Robert | Gen Counsel & Corp Secretary | 03/31/2021 | 61 |
| Sender Gary | Chief Financial Officer | 02/28/2021 | 74 |
| Schroeder Theodore R | Chief Executive Officer | 02/28/2021 | 253 |
| Schranz Jennifer | Chief Medical Officer | 02/28/2021 | 79 |
| Gelone Steven P. | President and COO | 02/28/2021 | 151 |
| Crotty Robert | Gen Counsel & Corp Secretary | 02/28/2021 | 91 |
| Crotty Robert | Gen Counsel & Corp Secretary | 01/31/2021 | 113 |
| Sender Gary | Chief Financial Officer | 01/31/2021 | 97 |
| Schroeder Theodore R | Chief Executive Officer | 01/31/2021 | 327 |
| Schranz Jennifer | Chief Medical Officer | 01/31/2021 | 94 |
| Gelone Steven P. | President and COO | 01/31/2021 | 196 |
| Sender Gary | Chief Financial Officer | 12/31/2020 | 77 |
| Schroeder Theodore R | Chief Executive Officer | 12/31/2020 | 293 |
| Gelone Steven P. | President and COO | 12/31/2020 | 152 |
| Crotty Robert | Gen Counsel & Corp Secretary | 12/31/2020 | 90 |
| Schranz Jennifer | Chief Medical Officer | 12/31/2020 | 73 |
| Sender Gary | Chief Financial Officer | 11/30/2020 | 133 |
| Schroeder Theodore R | Chief Executive Officer | 11/30/2020 | 517 |
| Schranz Jennifer | Chief Medical Officer | 11/30/2020 | 129 |
| Gelone Steven P. | President and COO | 11/30/2020 | 268 |
| Crotty Robert | Gen Counsel & Corp Secretary | 11/30/2020 | 157 |
| Sender Gary | Chief Financial Officer | 10/31/2020 | 155 |
| Schroeder Theodore R | Chief Executive Officer | 10/31/2020 | 600 |
| Schranz Jennifer | Chief Medical Officer | 10/31/2020 | 149 |
| Gelone Steven P. | President and COO | 10/31/2020 | 311 |
| Crotty Robert | Gen Counsel & Corp Secretary | 10/31/2020 | 181 |
| Sender Gary | Chief Financial Officer | 09/30/2020 | 166 |
| Schroeder Theodore R | Chief Executive Officer | 09/30/2020 | 645 |
| Schranz Jennifer | Chief Medical Officer | 09/30/2020 | 160 |
| Lavino Francesco Maria | Chief Commercial Officer | 09/30/2020 | 195 |
| Gelone Steven P. | President and COO | 09/30/2020 | 335 |
| Crotty Robert | Gen Counsel & Corp Secretary | 09/30/2020 | 195 |
| Sender Gary | Chief Financial Officer | 08/31/2020 | 193 |
| Gelone Steven P. | President and COO | 08/31/2020 | 389 |
| Lavino Francesco Maria | Chief Commercial Officer | 08/31/2020 | 227 |
| Schranz Jennifer | Chief Medical Officer | 08/31/2020 | 186 |
| Schroeder Theodore R | Chief Executive Officer | 08/31/2020 | 750 |
| Crotty Robert | Gen Counsel & Corp Secretary | 08/31/2020 | 227 |
| Gelone Steven P. | President and COO | 08/20/2020 | 5,026 |
| Lavino Francesco Maria | Chief Commercial Officer | 08/20/2020 | 2,434 |
| Crotty Robert | Gen Counsel & Corp Secretary | 08/20/2020 | 2,434 |
| Broom Colin MD | Director | 08/20/2020 | 7,165 |
| Sender Gary | Chief Financial Officer | 08/20/2020 | 2,075 |
| Crotty Robert | Gen Counsel & Corp Secretary | 07/31/2020 | 278 |
| Gelone Steven P. | President and COO | 07/31/2020 | 477 |
| Lavino Francesco Maria | Chief Commercial Officer | 07/31/2020 | 278 |
| Schranz Jennifer | Chief Medical Officer | 07/31/2020 | 229 |
| Schroeder Theodore R | Chief Executive Officer | 07/31/2020 | 920 |
| Sender Gary | Chief Financial Officer | 07/31/2020 | 237 |
| Lavino Francesco Maria | Chief Commercial Officer | 06/30/2020 | 247 |
| Schranz Jennifer | Chief Medical Officer | 06/30/2020 | 203 |
| Schroeder Theodore R | Chief Executive Officer | 06/30/2020 | 817 |
| Sender Gary | Chief Financial Officer | 06/30/2020 | 210 |
| Crotty Robert | Gen Counsel & Corp Secretary | 06/30/2020 | 247 |
| Gelone Steven P. | President and COO | 06/30/2020 | 424 |
| Sender Gary | Chief Financial Officer | 05/31/2020 | 356 |
| Gelone Steven P. | President and COO | 05/31/2020 | 716 |
| Schroeder Theodore R | Chief Executive Officer | 05/31/2020 | 1,381 |
| Schranz Jennifer | Chief Medical Officer | 05/31/2020 | 343 |
| Lavino Francesco Maria | Chief Commercial Officer | 05/31/2020 | 417 |
| Crotty Robert | Gen Counsel & Corp Secretary | 05/31/2020 | 417 |
| Crotty Robert | Gen Counsel & Corp Secretary | 04/30/2020 | 201 |
| Sender Gary | Chief Financial Officer | 04/30/2020 | 165 |
| Schranz Jennifer | Chief Medical Officer | 04/30/2020 | 165 |
| Schroeder Theodore R | Chief Executive Officer | 04/30/2020 | 664 |
| Gelone Steven P. | President and COO | 04/30/2020 | 332 |
| Lavino Francesco Maria | Chief Commercial Officer | 04/30/2020 | 201 |
| Gelone Steven P. | President and COO | 03/31/2020 | 348 |
| Sender Gary | Chief Financial Officer | 03/31/2020 | 173 |
| Lavino Francesco Maria | Chief Commercial Officer | 03/31/2020 | 210 |
| Crotty Robert | Gen Counsel & Corp Secretary | 03/31/2020 | 210 |
| Schroeder Theodore R | Chief Executive Officer | 03/31/2020 | 696 |
| Schranz Jennifer | Chief Medical Officer | 03/31/2020 | 173 |
| Schroeder Theodore R | Chief Executive Officer | 02/28/2020 | 1,635 |
| Gelone Steven P. | President & COO | 02/28/2020 | 818 |
| Sender Gary | Chief Financial Officer | 02/28/2020 | 406 |
| Schranz Jennifer | Chief Medical Officer | 02/28/2020 | 406 |
| Lavino Francesco Maria | Chief Commercial Officer | 02/28/2020 | 494 |
| Crotty Robert | Gen Counsel & Corp Secretary | 02/28/2020 | 494 |
| Schranz Jennifer | Chief Medical Officer | 01/31/2020 | 5,798 |
| Gelone Steven P. | President & COO | 01/31/2020 | 11,679 |
| Sender Gary | Chief Financial Officer | 01/31/2020 | 5,798 |
| Lavino Francesco Maria | Chief Commercial Officer | 01/31/2020 | 5,254 |
| Schroeder Theodore R | Chief Executive Officer | 01/31/2020 | 21,973 |
| Crotty Robert | Gen Counsel & Corp Secretary | 01/31/2020 | 5,254 |
| Broom Colin MD | Director | 08/30/2019 | 20,668 |
| Schroeder Theodore R | Chief Executive Officer | 08/27/2019 | 89,500 |
| Lavino Francesco Maria | Chief Commercial Officer | 08/22/2019 | 9,780 |
| Broom Colin MD | Director | 08/21/2019 | 21,066 |
| Gelone Steven P. | President & COO | 08/21/2019 | 17,068 |
| Crotty Robert | Gen Counsel & Corp Secretary | 08/21/2019 | 7,898 |
| Sender Gary | Chief Financial Officer | 08/21/2019 | 7,051 |
| Lavino Francesco Maria | Chief Commercial Officer | 08/21/2019 | 7,898 |
| Sender Gary | Chief Financial Officer | 08/21/2019 | 7,051 |
| Broom Colin MD | Director | 08/21/2019 | 21,066 |
| Crotty Robert | Gen Counsel & Corp Secretary | 08/21/2019 | 7,898 |
| Lavino Francesco Maria | Chief Commercial Officer | 08/21/2019 | 7,898 |
| Gelone Steven P. | President and COO | 08/21/2019 | 17,068 |
| Rowland Charles A Jr | Director | 12/24/2018 | 69,430 |
| Talbot George Harrison | Director | 07/31/2018 | 39,875 |
| BURGESS DANIEL D | Director | 07/31/2018 | 99,000 |
| Gelone Steven P. | Chief Scientific Officer | 06/23/2018 | 38,200 |
| Schranz Jennifer | Chief Medical Officer | 06/22/2018 | 20,515 |
| Broom Colin MD | CEO & Director | 06/22/2018 | 18,600 |
| Lavino Francesco Maria | Chief Commercial Officer | 05/23/2018 | 9,936 |
| Sender Gary | Chief Financial Officer | 05/23/2018 | 9,140 |
| Webster Stephen W | Director | 05/23/2018 | 36,720 |
| Broom Colin MD | CEO & Director | 05/23/2018 | 46,000 |
| Crotty Robert | General Counsel & Secretary | 05/23/2018 | 44,800 |
| Lavino Francesco Maria | Chief Commercial Officer | 11/29/2017 | 9,869 |
| Sender Gary | Chief Financial Officer | 09/22/2017 | 16,420 |
| Broom Colin MD | Chief Executive Officer | 09/22/2017 | 21,610 |
| Vivo Capital VIII, LLC | 10% Owner | 09/18/2017 | 60,412 |
| Vivo Capital VIII, LLC | 10% Owner | 09/18/2017 | 437,478 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 09/13/2017 | 193,956 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 09/12/2017 | 90,236 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 09/14/2017 | 29,224 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 08/31/2017 | 6,071 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 08/08/2017 | 21,137 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 08/07/2017 | 186,795 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 07/28/2017 | 69,195 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 07/24/2017 | 1,680 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 07/20/2017 | 246,173 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 07/19/2017 | 218,253 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 06/30/2017 | 19,420 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 07/03/2017 | 124,250 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 06/29/2017 | 17,189 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 06/28/2017 | 53,158 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 06/27/2017 | 23,457 |
| Talbot George Harrison | Director | 06/15/2017 | 9,410 |
| Talbot George Harrison | Director | 06/19/2017 | 4,186 |
| Talbot George Harrison | Director | 06/16/2017 | 2,244 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 06/01/2017 | 4,508 |
| Talbot George Harrison | Director | 05/30/2017 | 21,265 |
| Talbot George Harrison | Director | 05/25/2017 | 29,693 |
| Talbot George Harrison | Director | 05/23/2017 | 2,991 |
| Talbot George Harrison | Director | 05/16/2017 | 15,413 |
| Talbot George Harrison | Director | 05/15/2017 | 5,075 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/28/2017 | 166,813 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/27/2017 | 1,100 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/26/2017 | 7,799 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/21/2017 | 28,937 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/20/2017 | 3,575 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/19/2017 | 130,434 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/18/2017 | 131,880 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/11/2017 | 98,034 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/13/2017 | 122,232 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/12/2017 | 148,653 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/10/2017 | 406,451 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/07/2017 | 235,931 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/06/2017 | 350,160 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/07/2017 | 235,931 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/06/2017 | 350,160 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 04/10/2017 | 406,451 |
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CHANGE IN SHARES OUTSTANDING
STOCK BUYBACKS
Period of Report
Previous Period
% Change in Shares
10-K/10-Q Filings
Quarter
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Period of Report: 12/31/2021
10-K/10-Q Filings: View
Previous Period
% Change in Shares
Quarter
06/30/2021
29.27%
2Q
12/31/2019
-41.58%
8Q
09/30/2019
-39.92%
9Q
03/31/2019
-36.90%
11Q
12/31/2018
-14.66%
12Q
09/30/2018
-4.45%
13Q
06/30/2018
11.95%
14Q
03/31/2018
17.44%
15Q
12/31/2017
45.32%
16Q
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