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INSIDER TRANSACTIONS FOR
| Owner | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| BEDU-ADDO FRANK | President/CEO | Dec 02, 2022 | Option Exercise | $9.78 | 175,184 | 1,713,299 | 690,866 | Dec 02, 2022, 04:47 PM |
| BEDU-ADDO FRANK | President/CEO | Dec 02, 2022 | Option Exercise | $6.57 | 219,535 | 1,442,345 | 866,050 | Dec 02, 2022, 04:47 PM |
| HILL MATTHEW C | Chief Financial Officer | Dec 13, 2021 | Buy | $9.00 | 100 | 900 | 4,075 | Dec 14, 2021, 09:10 AM |
| HILL MATTHEW C | Chief Financial Officer | Dec 13, 2021 | Buy | $9.00 | 100 | 900 | 3,975 | Dec 14, 2021, 09:10 AM |
| HILL MATTHEW C | Chief Financial Officer | Dec 13, 2021 | Buy | $8.99 | 2,900 | 26,060 | 3,875 | Dec 14, 2021, 09:10 AM |
| Ali-Jackson Kamil | Director | Jun 15, 2021 | Buy | $8.50 | 11,764 | 99,994 | 11,764 | Jun 17, 2021, 07:09 PM |
| VAN VOORHEES SETH | Chief Financial Officer | Jun 15, 2021 | Buy | $8.50 | 17,647 | 150,000 | 17,647 | Jun 17, 2021, 06:52 PM |
| Freitag Gregory Gene | Director | Feb 14, 2020 | Option Exercise | $1.30 | 38,400 | 49,920 | 40,271 | Feb 19, 2020, 04:31 PM |
| SYKES RICHARD | Director | Feb 14, 2020 | Option Exercise | $1.30 | 384,615 | 499,999 | 445,108 | Feb 19, 2020, 04:30 PM |
| Saik Andrew | Chief Financial Officer | Feb 14, 2020 | Option Exercise | $1.30 | 38,400 | 49,920 | 42,549 | Feb 19, 2020, 04:30 PM |
| Glover Steve C | Director | Feb 14, 2020 | Option Exercise | $1.30 | 38,400 | 49,920 | 57,908 | Feb 19, 2020, 04:30 PM |
| Macdonald R. Loch | Chief Scientific Officer | Mar 22, 2018 | Sale | $16.41 | 2,500 | 41,025 | 570,602 | Mar 22, 2018, 04:03 PM |
| Macdonald R. Loch | Chief Scientific Officer | Mar 21, 2018 | Sale | $16.52 | 2,500 | 41,300 | 573,102 | Mar 21, 2018, 11:34 AM |
| Macdonald R. Loch | Chief Scientific Officer | Mar 20, 2018 | Sale | $16.47 | 5,000 | 82,350 | 575,602 | Mar 21, 2018, 11:34 AM |
| Macdonald R. Loch | Chief Scientific Officer | Mar 19, 2018 | Sale | $16.66 | 2,500 | 41,650 | 580,602 | Mar 21, 2018, 11:34 AM |
| Leuthner Brian A | President and CEO | Mar 02, 2018 | Sale | $15.08 | 2,500 | 37,700 | 70,236 | Mar 05, 2018, 08:19 AM |
| Leuthner Brian A | President and CEO | Mar 01, 2018 | Sale | $14.81 | 2,500 | 37,025 | 72,736 | Mar 05, 2018, 08:19 AM |
| Leuthner Brian A | President and CEO | Feb 23, 2018 | Sale | $15.37 | 2,500 | 38,425 | 75,236 | Feb 23, 2018, 05:28 PM |
| Leuthner Brian A | President and CEO | Feb 22, 2018 | Sale | $15.47 | 2,500 | 38,675 | 77,736 | Feb 23, 2018, 05:28 PM |
| Macdonald R. Loch | Chief Scientific Officer | Feb 22, 2018 | Sale | $14.49 | 2,500 | 36,225 | 583,102 | Feb 22, 2018, 05:00 PM |
| Macdonald R. Loch | Chief Scientific Officer | Feb 21, 2018 | Sale | $13.82 | 5,000 | 69,100 | 585,602 | Feb 22, 2018, 05:00 PM |
| Macdonald R. Loch | Chief Scientific Officer | Feb 20, 2018 | Sale | $13.75 | 5,000 | 68,750 | 590,602 | Feb 22, 2018, 05:00 PM |
| Leuthner Brian A | President and CEO | Feb 02, 2018 | Sale | $12.96 | 2,500 | 32,400 | 80,236 | Feb 02, 2018, 09:15 PM |
| Leuthner Brian A | President and CEO | Feb 01, 2018 | Sale | $13.14 | 2,500 | 32,850 | 82,736 | Feb 02, 2018, 09:15 PM |
| Leuthner Brian A | President and CEO | Jan 03, 2018 | Sale | $10.11 | 2,500 | 25,275 | 85,236 | Jan 03, 2018, 06:48 PM |
| Leuthner Brian A | President and CEO | Jan 02, 2018 | Sale | $10.11 | 2,500 | 25,275 | 87,736 | Jan 03, 2018, 06:48 PM |
| Leuthner Brian A | President and CEO | Dec 01, 2017 | Sale | $9.92 | 2,500 | 24,800 | 95,236 | Dec 05, 2017, 05:39 PM |
| Leuthner Brian A | President and CEO | Dec 05, 2017 | Sale | $9.68 | 2,500 | 24,200 | 90,236 | Dec 05, 2017, 05:39 PM |
| Leuthner Brian A | President and CEO | Dec 04, 2017 | Sale | $9.97 | 2,500 | 24,925 | 92,736 | Dec 05, 2017, 05:39 PM |
| MARCHIO ALBERT N II | Chief Accounting & Adm Officer | Nov 22, 2017 | Sale | $10.00 | 3,361 | 33,610 | 0 | Nov 22, 2017, 03:08 PM |
| Leuthner Brian A | President and CEO | Nov 03, 2017 | Sale | $10.86 | 2,500 | 27,150 | 97,736 | Nov 03, 2017, 05:53 PM |
| Leuthner Brian A | President and CEO | Nov 02, 2017 | Sale | $10.94 | 2,500 | 27,350 | 100,236 | Nov 03, 2017, 05:53 PM |
| Leuthner Brian A | President and CEO | Nov 01, 2017 | Sale | $10.92 | 2,500 | 27,300 | 102,736 | Nov 03, 2017, 05:53 PM |
| Leuthner Brian A | President and CEO | Oct 02, 2017 | Sale | $10.81 | 2,500 | 27,025 | 110,236 | Oct 04, 2017, 05:52 PM |
| Leuthner Brian A | President and CEO | Oct 04, 2017 | Sale | $11.14 | 2,500 | 27,850 | 105,236 | Oct 04, 2017, 05:52 PM |
| Leuthner Brian A | President and CEO | Oct 03, 2017 | Sale | $10.93 | 2,500 | 27,325 | 107,736 | Oct 04, 2017, 05:52 PM |
| Leuthner Brian A | President and CEO | Sep 06, 2017 | Sale | $10.31 | 2,500 | 25,775 | 112,736 | Sep 06, 2017, 08:01 PM |
| Leuthner Brian A | President and CEO | Sep 05, 2017 | Sale | $9.94 | 2,500 | 24,850 | 115,236 | Sep 06, 2017, 08:01 PM |
| Leuthner Brian A | President and CEO | Sep 01, 2017 | Sale | $10.37 | 2,500 | 25,925 | 117,736 | Sep 06, 2017, 08:01 PM |
| MARCHIO ALBERT N II | Chief Accounting & Adm Officer | Aug 29, 2017 | Sale | $10.42 | 2,500 | 26,050 | 3,361 | Aug 29, 2017, 05:30 PM |
| MARCHIO ALBERT N II | Chief Accounting & Adm Officer | Aug 23, 2017 | Sale | $10.39 | 1,000 | 10,390 | 5,861 | Aug 24, 2017, 04:11 PM |
| Leuthner Brian A | President and CEO | Aug 03, 2017 | Sale | $10.40 | 2,500 | 26,000 | 120,236 | Aug 03, 2017, 08:45 PM |
| Leuthner Brian A | President and CEO | Aug 02, 2017 | Sale | $10.53 | 2,500 | 26,325 | 122,736 | Aug 03, 2017, 08:45 PM |
| Leuthner Brian A | President and CEO | Aug 01, 2017 | Sale | $10.65 | 2,500 | 26,625 | 125,236 | Aug 03, 2017, 08:45 PM |
| BARER SOL J | Director | Jul 07, 2017 | Option Exercise | $2.39 | 12,530 | 29,947 | 658,075 | Jul 10, 2017, 03:51 PM |
| Leuthner Brian A | President and CEO | Jul 06, 2017 | Sale | $10.08 | 2,500 | 25,200 | 127,736 | Jul 06, 2017, 05:50 PM |
| Leuthner Brian A | President and CEO | Jul 05, 2017 | Sale | $10.21 | 2,500 | 25,525 | 130,236 | Jul 06, 2017, 05:50 PM |
| Leuthner Brian A | President and CEO | Jul 03, 2017 | Sale | $10.27 | 2,500 | 25,675 | 132,736 | Jul 06, 2017, 05:50 PM |
| Leuthner Brian A | President and CEO | Apr 26, 2017 | Sale | $11.10 | 100 | 1,110 | 135,236 | May 09, 2017, 03:33 PM |
| Einhorn Andrew J. | Chief Financial Officer | Mar 01, 2017 | Option Exercise | $2.39 | 1,567 | 3,745 | 43,223 | Mar 13, 2017, 01:47 PM |
| LOUGHLIN JAMES J | Director | Mar 06, 2017 | Buy | $9.24 | 3,000 | 27,720 | 6,000 | Mar 07, 2017, 03:33 PM |
| Leuthner Brian A | President and CEO | Feb 07, 2017 | Sale | $9.52 | 1,500 | 14,280 | 245,479 | Feb 08, 2017, 03:53 PM |
| Leuthner Brian A | President and CEO | Feb 06, 2017 | Sale | $9.52 | 1,500 | 14,280 | 246,979 | Feb 07, 2017, 04:12 PM |
| Leuthner Brian A | President and CEO | Feb 03, 2017 | Sale | $9.69 | 1,500 | 14,535 | 248,479 | Feb 07, 2017, 04:12 PM |
| Leuthner Brian A | President and CEO | Feb 02, 2017 | Sale | $9.61 | 1,500 | 14,415 | 249,979 | Feb 03, 2017, 03:25 PM |
| Leuthner Brian A | President and CEO | Feb 01, 2017 | Sale | $9.38 | 1,500 | 14,070 | 251,479 | Feb 03, 2017, 03:25 PM |
| Macdonald R. Loch | Chief Scientific Officer | Jan 23, 2017 | Option Exercise | $2.04 | 25,000 | 51,000 | 595,602 | Jan 25, 2017, 09:35 AM |
| Leuthner Brian A | President and CEO | Dec 01, 2016 | Sale | $11.60 | 7,500 | 87,000 | 252,979 | Dec 02, 2016, 03:00 PM |
| Leuthner Brian A | President and CEO | Oct 03, 2016 | Sale | $10.25 | 7,500 | 76,844 | 260,479 | Oct 04, 2016, 11:16 AM |
| MIDDLEKAUFF W BRADFORD | Senior VP, GC and Secretary | Aug 05, 2016 | Buy | $9.48 | 9,857 | 93,444 | 9,857 | Aug 09, 2016, 09:23 AM |
| MIDDLEKAUFF W BRADFORD | Senior VP, GC and Secretary | Aug 08, 2016 | Buy | $9.43 | 143 | 1,348 | 10,000 | Aug 09, 2016, 09:23 AM |
| Leuthner Brian A | President and CEO | Aug 01, 2016 | Sale | $9.54 | 7,500 | 71,581 | 267,979 | Aug 02, 2016, 03:41 PM |
| Vaish Renu | V.P., Global Reg. Affairs | Jun 16, 2016 | Option Exercise | $5.13 | 5,000 | 25,650 | 5,350 | Jun 20, 2016, 11:51 AM |
| HEALY JAMES | Director | Mar 11, 2016 | Buy | $7.30 | 541,343 | 3,951,641 | 2,852,711 | Mar 15, 2016, 05:57 PM |
| LOUGHLIN JAMES J | Director | Mar 11, 2016 | Buy | $7.63 | 3,000 | 22,901 | 3,000 | Mar 15, 2016, 04:04 PM |
| BARER SOL J | Director | Oct 06, 2015 | Option Exercise | $6.17 | 12,735 | 78,575 | 645,545 | Oct 08, 2015, 04:16 PM |
| BARER SOL J | Director | Oct 06, 2015 | Buy | $11.00 | 45,000 | 495,000 | 632,810 | Oct 08, 2015, 04:16 PM |
| LOUGHLIN JAMES J | Director | Oct 06, 2015 | Option Exercise | $8.60 | 364 | 3,130 | 19,625 | Oct 08, 2015, 04:16 PM |
| LOUGHLIN JAMES J | Director | Oct 06, 2015 | Buy | $11.00 | 7,000 | 77,000 | 19,261 | Oct 08, 2015, 04:16 PM |
| HEALY JAMES | Director | Oct 06, 2015 | Option Exercise | $8.60 | 53,665 | 461,519 | 2,311,368 | Oct 08, 2015, 04:14 PM |
| Spiegel Robert J. | Director | Oct 06, 2015 | Option Exercise | $7.91 | 1,549 | 12,253 | 38,661 | Oct 08, 2015, 04:14 PM |
| Spiegel Robert J. | Director | Oct 06, 2015 | Buy | $11.00 | 3,000 | 33,000 | 37,112 | Oct 08, 2015, 04:14 PM |
| HEALY JAMES | Director | Oct 06, 2015 | Buy | $11.00 | 450,000 | 4,950,000 | 2,257,703 | Oct 08, 2015, 04:14 PM |
| Macdonald R. Loch | Chief Scientific Officer | Oct 06, 2015 | Option Exercise | $7.90 | 194 | 1,533 | 570,602 | Oct 08, 2015, 04:14 PM |
| Einhorn Andrew J. | Chief Financial Officer | Oct 06, 2015 | Option Exercise | $7.75 | 1,651 | 12,795 | 83,592 | Oct 08, 2015, 04:13 PM |
| Einhorn Andrew J. | Chief Financial Officer | Oct 06, 2015 | Option Exercise | $6.79 | 2,377 | 16,140 | 41,656 | Oct 08, 2015, 04:13 PM |
| Einhorn Andrew J. | Chief Financial Officer | Oct 06, 2015 | Buy | $11.00 | 45,000 | 495,000 | 81,941 | Oct 08, 2015, 04:13 PM |
| Hove Anders D | Director | Oct 06, 2015 | Option Exercise | $8.60 | 46,665 | 401,319 | 2,068,582 | Oct 08, 2015, 04:11 PM |
| Hove Anders D | Director | Oct 06, 2015 | Buy | $11.00 | 450,000 | 4,950,000 | 2,021,917 | Oct 08, 2015, 04:11 PM |
| Leuthner Brian A | Chief Executive Officer | Oct 06, 2015 | Option Exercise | $8.60 | 80 | 688 | 550,958 | Oct 08, 2015, 04:11 PM |
| MARCHIO ALBERT N II | Chief Acct. & Op., Asst. Sec. | Oct 06, 2015 | Option Exercise | $7.24 | 357 | 2,585 | 6,861 | Oct 08, 2015, 04:10 PM |
| MARCHIO ALBERT N II | Chief Acct. & Op., Asst. Sec. | Oct 06, 2015 | Buy | $11.00 | 100 | 1,100 | 6,504 | Oct 08, 2015, 04:10 PM |
| Vaish Renu | V.P., Global Reg. Affairs | Oct 06, 2015 | Buy | $11.00 | 350 | 3,850 | 350 | Oct 08, 2015, 04:09 PM |
| Faleck Herbert J | Chief Medical Officer | Oct 06, 2015 | Buy | $11.00 | 500 | 5,500 | 500 | Oct 08, 2015, 04:07 PM |
Load More Insider Transactions
Buy
Sale
Option Exercise
| Owner | Relationship | Date | Value($) |
| BEDU-ADDO FRANK | President/CEO | 12/02/2022 | 1,713,299 |
| BEDU-ADDO FRANK | President/CEO | 12/02/2022 | 1,442,345 |
| HILL MATTHEW C | Chief Financial Officer | 12/13/2021 | 900 |
| HILL MATTHEW C | Chief Financial Officer | 12/13/2021 | 900 |
| HILL MATTHEW C | Chief Financial Officer | 12/13/2021 | 26,060 |
| Ali-Jackson Kamil | Director | 06/15/2021 | 99,994 |
| VAN VOORHEES SETH | Chief Financial Officer | 06/15/2021 | 150,000 |
| Freitag Gregory Gene | Director | 02/14/2020 | 49,920 |
| SYKES RICHARD | Director | 02/14/2020 | 499,999 |
| Saik Andrew | Chief Financial Officer | 02/14/2020 | 49,920 |
| Glover Steve C | Director | 02/14/2020 | 49,920 |
| Macdonald R. Loch | Chief Scientific Officer | 03/22/2018 | 41,025 |
| Macdonald R. Loch | Chief Scientific Officer | 03/21/2018 | 41,300 |
| Macdonald R. Loch | Chief Scientific Officer | 03/20/2018 | 82,350 |
| Macdonald R. Loch | Chief Scientific Officer | 03/19/2018 | 41,650 |
| Leuthner Brian A | President and CEO | 03/02/2018 | 37,700 |
| Leuthner Brian A | President and CEO | 03/01/2018 | 37,025 |
| Leuthner Brian A | President and CEO | 02/23/2018 | 38,425 |
| Leuthner Brian A | President and CEO | 02/22/2018 | 38,675 |
| Macdonald R. Loch | Chief Scientific Officer | 02/22/2018 | 36,225 |
| Macdonald R. Loch | Chief Scientific Officer | 02/21/2018 | 69,100 |
| Macdonald R. Loch | Chief Scientific Officer | 02/20/2018 | 68,750 |
| Leuthner Brian A | President and CEO | 02/02/2018 | 32,400 |
| Leuthner Brian A | President and CEO | 02/01/2018 | 32,850 |
| Leuthner Brian A | President and CEO | 01/03/2018 | 25,275 |
| Leuthner Brian A | President and CEO | 01/02/2018 | 25,275 |
| Leuthner Brian A | President and CEO | 12/01/2017 | 24,800 |
| Leuthner Brian A | President and CEO | 12/05/2017 | 24,200 |
| Leuthner Brian A | President and CEO | 12/04/2017 | 24,925 |
| MARCHIO ALBERT N II | Chief Accounting & Adm Officer | 11/22/2017 | 33,610 |
| Leuthner Brian A | President and CEO | 11/03/2017 | 27,150 |
| Leuthner Brian A | President and CEO | 11/02/2017 | 27,350 |
| Leuthner Brian A | President and CEO | 11/01/2017 | 27,300 |
| Leuthner Brian A | President and CEO | 10/02/2017 | 27,025 |
| Leuthner Brian A | President and CEO | 10/04/2017 | 27,850 |
| Leuthner Brian A | President and CEO | 10/03/2017 | 27,325 |
| Leuthner Brian A | President and CEO | 09/06/2017 | 25,775 |
| Leuthner Brian A | President and CEO | 09/05/2017 | 24,850 |
| Leuthner Brian A | President and CEO | 09/01/2017 | 25,925 |
| MARCHIO ALBERT N II | Chief Accounting & Adm Officer | 08/29/2017 | 26,050 |
| MARCHIO ALBERT N II | Chief Accounting & Adm Officer | 08/23/2017 | 10,390 |
| Leuthner Brian A | President and CEO | 08/03/2017 | 26,000 |
| Leuthner Brian A | President and CEO | 08/02/2017 | 26,325 |
| Leuthner Brian A | President and CEO | 08/01/2017 | 26,625 |
| BARER SOL J | Director | 07/07/2017 | 29,947 |
| Leuthner Brian A | President and CEO | 07/06/2017 | 25,200 |
| Leuthner Brian A | President and CEO | 07/05/2017 | 25,525 |
| Leuthner Brian A | President and CEO | 07/03/2017 | 25,675 |
| Leuthner Brian A | President and CEO | 04/26/2017 | 1,110 |
| Einhorn Andrew J. | Chief Financial Officer | 03/01/2017 | 3,745 |
| LOUGHLIN JAMES J | Director | 03/06/2017 | 27,720 |
| Leuthner Brian A | President and CEO | 02/07/2017 | 14,280 |
| Leuthner Brian A | President and CEO | 02/06/2017 | 14,280 |
| Leuthner Brian A | President and CEO | 02/03/2017 | 14,535 |
| Leuthner Brian A | President and CEO | 02/02/2017 | 14,415 |
| Leuthner Brian A | President and CEO | 02/01/2017 | 14,070 |
| Macdonald R. Loch | Chief Scientific Officer | 01/23/2017 | 51,000 |
| Leuthner Brian A | President and CEO | 12/01/2016 | 87,000 |
| Leuthner Brian A | President and CEO | 10/03/2016 | 76,844 |
| MIDDLEKAUFF W BRADFORD | Senior VP, GC and Secretary | 08/05/2016 | 93,444 |
| MIDDLEKAUFF W BRADFORD | Senior VP, GC and Secretary | 08/08/2016 | 1,348 |
| Leuthner Brian A | President and CEO | 08/01/2016 | 71,581 |
| Vaish Renu | V.P., Global Reg. Affairs | 06/16/2016 | 25,650 |
| HEALY JAMES | Director | 03/11/2016 | 3,951,641 |
| LOUGHLIN JAMES J | Director | 03/11/2016 | 22,901 |
| BARER SOL J | Director | 10/06/2015 | 78,575 |
| BARER SOL J | Director | 10/06/2015 | 495,000 |
| LOUGHLIN JAMES J | Director | 10/06/2015 | 3,130 |
| LOUGHLIN JAMES J | Director | 10/06/2015 | 77,000 |
| HEALY JAMES | Director | 10/06/2015 | 461,519 |
| Spiegel Robert J. | Director | 10/06/2015 | 12,253 |
| Spiegel Robert J. | Director | 10/06/2015 | 33,000 |
| HEALY JAMES | Director | 10/06/2015 | 4,950,000 |
| Macdonald R. Loch | Chief Scientific Officer | 10/06/2015 | 1,533 |
| Einhorn Andrew J. | Chief Financial Officer | 10/06/2015 | 12,795 |
| Einhorn Andrew J. | Chief Financial Officer | 10/06/2015 | 16,140 |
| Einhorn Andrew J. | Chief Financial Officer | 10/06/2015 | 495,000 |
| Hove Anders D | Director | 10/06/2015 | 401,319 |
| Hove Anders D | Director | 10/06/2015 | 4,950,000 |
| Leuthner Brian A | Chief Executive Officer | 10/06/2015 | 688 |
| MARCHIO ALBERT N II | Chief Acct. & Op., Asst. Sec. | 10/06/2015 | 2,585 |
| MARCHIO ALBERT N II | Chief Acct. & Op., Asst. Sec. | 10/06/2015 | 1,100 |
| Vaish Renu | V.P., Global Reg. Affairs | 10/06/2015 | 3,850 |
| Faleck Herbert J | Chief Medical Officer | 10/06/2015 | 5,500 |
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CHANGE IN SHARES OUTSTANDING FOR
STOCK BUYBACKS FOR
Period of Report
Previous Period
% Change in Shares
10-K/10-Q Filings
Quarter
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Period of Report: 12/31/2023
10-K/10-Q Filings: View
Previous Period
% Change in Shares
Quarter
09/30/2023
2.43%
1Q
06/30/2023
2.79%
2Q
03/31/2023
4.05%
3Q
12/31/2022
9.04%
4Q
09/30/2022
11.26%
5Q
06/30/2022
11.28%
6Q
03/31/2022
21.03%
7Q
12/31/2021
11.21%
8Q
09/30/2021
11.38%
9Q
06/30/2021
36.71%
10Q
03/31/2021
42.21%
11Q
12/31/2020
89.08%
12Q
09/30/2020
66.98%
13Q
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BUYBACK ANNOUNCEMENT(S) FOR
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