Aerpio Pharmaceuticals Inc. (ARPO) NASDAQ

$2.20 0 (0.00%)

Market Cap: $104.85M

As of 08/26/21 12:00 AM EDT. Market closed.

(ARPO)

Aerpio Pharmaceuticals Inc. (ARPO) NASDAQ

$2.20 0 (0.00%)

Market Cap: $104.85M

As of 08/26/21 12:00 AM EDT. Market closed.

Aerpio Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing compounds that activate Tie2 for indications in which the Company believes that activation of Tie2 may have therapeutic potential. The Company's lead compound, razuprotafib (formerly AKB-9778), a first-in-class small molecule inhibitor of vascular endothelial protein tyrosine phosphatase ("VE-PTP"). The Company is ... read more

Aerpio Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing compounds that activate Tie2 for indications in which the Company believes that activation of Tie2 may have therapeutic potential. The Company's lead compound, razuprotafib (formerly AKB-9778), a first-in-class small molecule inhibitor of vascular endothelial protein tyrosine phosphatase ("VE-PTP"). The Company is also evaluating development options for ARP-1536, a humanized monoclonal antibody, for its therapeutic potential in the treatment of diabetic vascular complications including nephropathy and diabetic macular edema ("DME"). The Company's third asset is a bispecific antibody that binds both VEGF and VE-PTP which is designed to inhibit VEGF activation and activate Tie2. This bispecific antibody has the potential to be an improved treatment for wet age-related macular degeneration and DME via intravitreal injection. Finally, the Company has exclusively out-licensed AKB-4924 (now called GB004), a first-in-class small molecule inhibitor of hypoxia-inducible factor-1 (HIF). GB004 is being developed by AKB-4924's exclusive licensor, Gossamer Bio, Inc.. In January 2021, the Company announced that it had initiated a process to explore and review a range of strategic alternatives focused on maximizing stockholder value from the Company's clinical assets and cash resources. read less

COMPANY PROFILE
Sector
Manufacturing
Industry
Medicinal and Botanical Manufacturing
URL
Address
9987 Carver Rd, Ohio, Blue Ash, 45242-5550.
Sector
Manufacturing
Industry
Medicinal and Botanical Manufacturing
Address
9987 Carver Rd, Ohio, Blue Ash, 45242-5550.
PRICE CHART
1w
1m
3m
6m
YTD
1y
5y
MAX
From: To:
KEY STATS
Open
$2.19
Previous Close
$2.20
Days Range
$2.16 - $2.30
52 week range
$0.95 - $3.32
Volume
826,001
Avg. Volume (30 days)
1,954,334
Market Cap
$104.85M
Dividend Yield
0.00%
P/E
-
Shares Outstanding
47,660,492
Open
$2.19
Previous Close
$2.20
Days Range
$2.16 - $2.30
52 week range
$0.95 - $3.32
Volume
826,001
Avg. Volume (30 days)
1,954,334
Market Cap
$104.85M
Dividend Yield
0.00%
P/E
-
Shares Outstanding
47,660,492

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

Open in: SeekingAlpha Yahoo Finance Fidelity MorningStar

INSIDER TRANSACTIONS FOR AERPIO PHARMACEUTICALS INC
Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
Desai Neil See Remarks Mar 18, 2022 Sale $20.07 3,550 71,234 1,915,543 Mar 22, 2022, 05:34 PM
Dalal Anupam Director Aug 26, 2021 Buy $13.08 1,529,402 19,999,989 1,529,402 Aug 31, 2021, 07:52 PM
Castelein Caley Director Aug 26, 2021 Buy $13.08 259,998 3,399,994 259,998 Aug 30, 2021, 09:11 PM
Dalal Anupam Director Aug 26, 2021 Buy $13.08 1,529,402 19,999,989 1,529,402 Aug 30, 2021, 08:39 PM
Aghazadeh Behzad Director Aug 26, 2021 Option Exercise $13.08 1,911,752 24,999,980 2,211,752 Aug 30, 2021, 07:39 PM
Dalal Anupam Director Jun 30, 2021 Option Exercise $1.52 7,400 11,248 16,959 Jul 02, 2021, 05:38 PM
Prelack Steven Director Jun 30, 2021 Option Exercise $1.52 12,334 18,748 24,485 Jul 02, 2021, 05:38 PM
Dugel Pravin Director Jun 30, 2021 Option Exercise $1.52 6,331 9,623 12,568 Jul 02, 2021, 05:38 PM
Castelein Caley Director Jun 30, 2021 Option Exercise $1.52 7,811 11,873 295,414 Jul 02, 2021, 05:37 PM
Cohen Cheryl Director Jun 30, 2021 Option Exercise $1.52 8,140 12,373 16,160 Jul 02, 2021, 05:34 PM
Cohen Cheryl Director Mar 31, 2021 Option Exercise $1.54 8,020 12,375 8,020 Apr 02, 2021, 08:30 PM
Dalal Anupam Director Mar 31, 2021 Option Exercise $1.54 7,290 11,248 9,559 Apr 02, 2021, 08:30 PM
Castelein Caley Director Mar 31, 2021 Option Exercise $1.54 7,696 11,875 287,603 Apr 02, 2021, 08:30 PM
ORBIMED ADVISORS LLC 10% Owner Dec 08, 2020 Sale $1.96 21,400 41,944 0 Dec 10, 2020, 05:04 PM
ORBIMED ADVISORS LLC 10% Owner Dec 08, 2020 Option Exercise $0.96 21,400 20,544 21,400 Dec 10, 2020, 05:04 PM
Gardner Joseph H. President Jul 10, 2019 Buy $0.81 5,000 4,074 453,019 Jul 10, 2019, 06:03 PM
Gardner Joseph H. President Jul 03, 2019 Buy $0.90 5,000 4,485 448,019 Jul 08, 2019, 05:51 PM
Novartis Bioventures Ltd 10% Owner Apr 26, 2019 Sale $1.03 138,704 142,865 4,049,804 Apr 29, 2019, 05:23 PM
Novartis Bioventures Ltd 10% Owner Apr 25, 2019 Sale $1.03 563,096 579,989 4,188,508 Apr 29, 2019, 05:23 PM
Novartis Bioventures Ltd 10% Owner Apr 24, 2019 Sale $1.03 16,403 16,895 4,751,604 Apr 24, 2019, 07:03 PM
Novartis Bioventures Ltd 10% Owner Apr 23, 2019 Sale $1.03 27,554 28,381 4,768,007 Apr 24, 2019, 07:03 PM
Novartis Bioventures Ltd 10% Owner Apr 22, 2019 Sale $0.97 7,100 6,887 4,795,561 Apr 24, 2019, 07:03 PM
Novartis Bioventures Ltd 10% Owner Apr 11, 2019 Sale $1.08 57,438 62,033 4,862,363 Apr 15, 2019, 09:26 PM
Novartis Bioventures Ltd 10% Owner Apr 15, 2019 Sale $0.99 28,794 28,506 4,802,661 Apr 15, 2019, 09:26 PM
Novartis Bioventures Ltd 10% Owner Apr 12, 2019 Sale $1.04 30,908 32,144 4,831,455 Apr 15, 2019, 09:26 PM
Novartis Bioventures Ltd 10% Owner Apr 10, 2019 Sale $1.09 140,230 152,851 4,919,801 Apr 10, 2019, 06:26 PM
Novartis Bioventures Ltd 10% Owner Apr 09, 2019 Sale $1.01 32,991 33,321 5,060,031 Apr 10, 2019, 06:26 PM
Novartis Bioventures Ltd 10% Owner Apr 08, 2019 Sale $1.02 27,525 28,075 5,093,022 Apr 10, 2019, 06:26 PM
Novartis Bioventures Ltd 10% Owner Apr 04, 2019 Sale $1.01 47,900 48,379 5,145,208 Apr 05, 2019, 05:14 PM
Novartis Bioventures Ltd 10% Owner Apr 03, 2019 Sale $0.96 58,033 55,712 5,193,108 Apr 05, 2019, 05:14 PM
Novartis Bioventures Ltd 10% Owner Apr 05, 2019 Sale $1.02 24,661 25,154 5,120,547 Apr 05, 2019, 05:14 PM
Novartis Bioventures Ltd 10% Owner Apr 02, 2019 Sale $0.97 51,754 50,201 5,251,141 Apr 02, 2019, 08:09 PM
Novartis Bioventures Ltd 10% Owner Apr 01, 2019 Sale $0.95 116,909 111,064 5,302,895 Apr 02, 2019, 08:09 PM
Novartis Bioventures Ltd 10% Owner Mar 29, 2019 Sale $0.91 63,100 57,421 5,419,804 Apr 02, 2019, 08:09 PM
Novartis Bioventures Ltd 10% Owner Mar 27, 2019 Sale $0.99 50,749 50,242 5,571,739 Mar 28, 2019, 05:16 PM
Novartis Bioventures Ltd 10% Owner Mar 26, 2019 Sale $1.01 177,762 179,540 5,622,488 Mar 28, 2019, 05:16 PM
Novartis Bioventures Ltd 10% Owner Mar 28, 2019 Sale $0.94 88,835 83,505 5,482,904 Mar 28, 2019, 05:16 PM
Satter Muneer A Director Jan 10, 2019 Buy $2.45 23,818 58,442 5,621,835 Jan 10, 2019, 09:00 PM
Satter Muneer A Director Jan 09, 2019 Buy $2.39 20,000 47,876 5,598,017 Jan 10, 2019, 09:00 PM
Satter Muneer A Director Jan 08, 2019 Buy $2.20 20,000 43,972 5,578,017 Jan 10, 2019, 09:00 PM
Satter Muneer A Director Jan 07, 2019 Buy $2.18 20,000 43,558 5,558,017 Jan 07, 2019, 09:00 PM
Satter Muneer A Director Jan 04, 2019 Buy $2.12 20,000 42,396 5,538,017 Jan 07, 2019, 09:00 PM
Satter Muneer A Director Jan 03, 2019 Buy $2.08 20,000 41,508 5,518,017 Jan 07, 2019, 09:00 PM
Satter Muneer A Director Dec 28, 2018 Buy $1.72 20,000 34,372 5,458,017 Jan 02, 2019, 09:01 PM
Satter Muneer A Director Jan 02, 2019 Buy $1.94 20,000 38,838 5,498,017 Jan 02, 2019, 09:01 PM
Satter Muneer A Director Dec 31, 2018 Buy $1.75 20,000 34,900 5,478,017 Jan 02, 2019, 09:01 PM
Satter Muneer A Director Dec 27, 2018 Buy $1.67 20,000 33,410 5,438,017 Dec 27, 2018, 07:13 PM
Satter Muneer A Director Dec 26, 2018 Buy $1.69 20,000 33,854 5,418,017 Dec 27, 2018, 07:13 PM
Satter Muneer A Director Dec 21, 2018 Buy $1.84 20,000 36,870 5,398,017 Dec 27, 2018, 07:13 PM
Satter Muneer A Director Dec 18, 2018 Buy $1.99 20,000 39,856 5,338,017 Dec 20, 2018, 07:04 PM
Satter Muneer A Director Dec 20, 2018 Buy $1.85 20,000 36,984 5,378,017 Dec 20, 2018, 07:04 PM
Satter Muneer A Director Dec 19, 2018 Buy $1.92 20,000 38,384 5,358,017 Dec 20, 2018, 07:04 PM
Satter Muneer A Director Dec 14, 2018 Buy $2.00 20,000 40,094 5,318,017 Dec 14, 2018, 08:55 PM
Satter Muneer A Director Dec 13, 2018 Buy $2.02 20,000 40,308 5,298,017 Dec 14, 2018, 08:55 PM
Satter Muneer A Director Dec 12, 2018 Buy $2.05 20,000 40,938 5,278,017 Dec 14, 2018, 08:55 PM
Satter Muneer A Director Dec 10, 2018 Buy $2.13 20,000 42,608 5,238,017 Dec 11, 2018, 08:52 PM
Satter Muneer A Director Dec 07, 2018 Buy $2.14 20,000 42,788 5,218,017 Dec 11, 2018, 08:52 PM
Satter Muneer A Director Dec 11, 2018 Buy $2.09 20,000 41,846 5,258,017 Dec 11, 2018, 08:52 PM
Satter Muneer A Director Dec 06, 2018 Buy $2.18 20,000 43,584 5,198,017 Dec 06, 2018, 08:54 PM
Satter Muneer A Director Dec 04, 2018 Buy $2.10 20,000 41,994 5,178,017 Dec 06, 2018, 08:54 PM
Satter Muneer A Director Dec 03, 2018 Buy $1.99 20,000 39,774 5,158,017 Dec 06, 2018, 08:54 PM
Satter Muneer A Director Nov 30, 2018 Buy $1.98 20,000 39,692 5,138,017 Nov 30, 2018, 09:00 PM
Satter Muneer A Director Nov 29, 2018 Buy $2.01 20,000 40,118 5,118,017 Nov 30, 2018, 09:00 PM
Satter Muneer A Director Nov 28, 2018 Buy $1.94 20,000 38,714 5,098,017 Nov 30, 2018, 09:00 PM
HOFFMAN STEPHEN J Chief Executive Officer Nov 12, 2018 Buy $2.01 30,000 60,300 31,967 Nov 14, 2018, 04:25 PM
HOFFMAN STEPHEN J Chief Executive Officer Nov 09, 2018 Buy $1.95 1,967 3,836 1,967 Nov 14, 2018, 04:25 PM
Novartis Bioventures Ltd 10% Owner Aug 20, 2018 Sale $3.90 5,300 20,670 5,800,250 Aug 22, 2018, 04:07 PM
ORBIMED ADVISORS LLC Director Jun 28, 2018 Buy $3.85 777,500 2,993,375 5,193,946 Jul 02, 2018, 04:56 PM
Khuong Chau Quang Director Jun 28, 2018 Buy $3.85 777,500 2,993,375 5,193,946 Jul 02, 2018, 04:51 PM
Satter Muneer A Director Jun 28, 2018 Buy $3.85 1,818,182 7,000,001 5,078,017 Jun 29, 2018, 04:17 PM
Satter Muneer A Director Mar 23, 2018 Buy $5.00 1,000 5,000 3,259,835 Mar 23, 2018, 06:23 PM
Satter Muneer A Director Mar 21, 2018 Buy $4.85 4,000 19,390 3,258,835 Mar 23, 2018, 06:23 PM
Satter Muneer A Director Mar 20, 2018 Buy $4.97 5,400 26,860 3,254,835 Mar 21, 2018, 04:52 PM
Satter Muneer A Director Mar 19, 2018 Buy $4.96 7,600 37,725 3,249,435 Mar 21, 2018, 04:52 PM
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Buy Sale Option Exercise
Owner Relationship Date Value($)
Desai Neil See Remarks 03/18/2022 71,234
Dalal Anupam Director 08/26/2021 19,999,989
Castelein Caley Director 08/26/2021 3,399,994
Dalal Anupam Director 08/26/2021 19,999,989
Aghazadeh Behzad Director 08/26/2021 24,999,980
Dalal Anupam Director 06/30/2021 11,248
Prelack Steven Director 06/30/2021 18,748
Dugel Pravin Director 06/30/2021 9,623
Castelein Caley Director 06/30/2021 11,873
Cohen Cheryl Director 06/30/2021 12,373
Cohen Cheryl Director 03/31/2021 12,375
Dalal Anupam Director 03/31/2021 11,248
Castelein Caley Director 03/31/2021 11,875
ORBIMED ADVISORS LLC 10% Owner 12/08/2020 41,944
ORBIMED ADVISORS LLC 10% Owner 12/08/2020 20,544
Gardner Joseph H. President 07/10/2019 4,074
Gardner Joseph H. President 07/03/2019 4,485
Novartis Bioventures Ltd 10% Owner 04/26/2019 142,865
Novartis Bioventures Ltd 10% Owner 04/25/2019 579,989
Novartis Bioventures Ltd 10% Owner 04/24/2019 16,895
Novartis Bioventures Ltd 10% Owner 04/23/2019 28,381
Novartis Bioventures Ltd 10% Owner 04/22/2019 6,887
Novartis Bioventures Ltd 10% Owner 04/11/2019 62,033
Novartis Bioventures Ltd 10% Owner 04/15/2019 28,506
Novartis Bioventures Ltd 10% Owner 04/12/2019 32,144
Novartis Bioventures Ltd 10% Owner 04/10/2019 152,851
Novartis Bioventures Ltd 10% Owner 04/09/2019 33,321
Novartis Bioventures Ltd 10% Owner 04/08/2019 28,075
Novartis Bioventures Ltd 10% Owner 04/04/2019 48,379
Novartis Bioventures Ltd 10% Owner 04/03/2019 55,712
Novartis Bioventures Ltd 10% Owner 04/05/2019 25,154
Novartis Bioventures Ltd 10% Owner 04/02/2019 50,201
Novartis Bioventures Ltd 10% Owner 04/01/2019 111,064
Novartis Bioventures Ltd 10% Owner 03/29/2019 57,421
Novartis Bioventures Ltd 10% Owner 03/27/2019 50,242
Novartis Bioventures Ltd 10% Owner 03/26/2019 179,540
Novartis Bioventures Ltd 10% Owner 03/28/2019 83,505
Satter Muneer A Director 01/10/2019 58,442
Satter Muneer A Director 01/09/2019 47,876
Satter Muneer A Director 01/08/2019 43,972
Satter Muneer A Director 01/07/2019 43,558
Satter Muneer A Director 01/04/2019 42,396
Satter Muneer A Director 01/03/2019 41,508
Satter Muneer A Director 12/28/2018 34,372
Satter Muneer A Director 01/02/2019 38,838
Satter Muneer A Director 12/31/2018 34,900
Satter Muneer A Director 12/27/2018 33,410
Satter Muneer A Director 12/26/2018 33,854
Satter Muneer A Director 12/21/2018 36,870
Satter Muneer A Director 12/18/2018 39,856
Satter Muneer A Director 12/20/2018 36,984
Satter Muneer A Director 12/19/2018 38,384
Satter Muneer A Director 12/14/2018 40,094
Satter Muneer A Director 12/13/2018 40,308
Satter Muneer A Director 12/12/2018 40,938
Satter Muneer A Director 12/10/2018 42,608
Satter Muneer A Director 12/07/2018 42,788
Satter Muneer A Director 12/11/2018 41,846
Satter Muneer A Director 12/06/2018 43,584
Satter Muneer A Director 12/04/2018 41,994
Satter Muneer A Director 12/03/2018 39,774
Satter Muneer A Director 11/30/2018 39,692
Satter Muneer A Director 11/29/2018 40,118
Satter Muneer A Director 11/28/2018 38,714
HOFFMAN STEPHEN J Chief Executive Officer 11/12/2018 60,300
HOFFMAN STEPHEN J Chief Executive Officer 11/09/2018 3,836
Novartis Bioventures Ltd 10% Owner 08/20/2018 20,670
ORBIMED ADVISORS LLC Director 06/28/2018 2,993,375
Khuong Chau Quang Director 06/28/2018 2,993,375
Satter Muneer A Director 06/28/2018 7,000,001
Satter Muneer A Director 03/23/2018 5,000
Satter Muneer A Director 03/21/2018 19,390
Satter Muneer A Director 03/20/2018 26,860
Satter Muneer A Director 03/19/2018 37,725
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