| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 24, 2026 | Tax Payment (Shares) | $485.11 | 1,627 | 789,274 | 19,100 | Feb 26, 2026, 06:00 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 25, 2026 | Sale | $486.35 | 668 | 324,882 | 18,432 | Feb 26, 2026, 06:00 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 17, 2026 | Sale | $489.46 | 2,031 | 994,093 | 21,544 | Feb 19, 2026, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 18, 2026 | Sale | $473.68 | 817 | 386,997 | 20,727 | Feb 19, 2026, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 17, 2026 | Tax Payment (Shares) | $483.75 | 1,530 | 740,138 | 23,575 | Feb 19, 2026, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 13, 2026 | Tax Payment (Shares) | $487.76 | 1,903 | 928,207 | 20,143 | Feb 18, 2026, 04:19 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 10, 2026 | Tax Payment (Shares) | $468.41 | 872 | 408,454 | 23,797 | Feb 12, 2026, 04:50 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 11, 2026 | Sale | $460.43 | 1,751 | 806,213 | 22,046 | Feb 12, 2026, 04:50 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Nov 17, 2025 | Sale | $434.58 | 2,500 | 1,086,450 | 16,852 | Nov 19, 2025, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 26, 2025 | Tax Payment (Shares) | $479.61 | 2,482 | 1,190,392 | 22,002 | Feb 28, 2025, 04:36 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 27, 2025 | Sale | $475.34 | 2,650 | 1,259,651 | 19,352 | Feb 28, 2025, 04:36 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 24, 2025 | Tax Payment (Shares) | $483.28 | 1,656 | 800,312 | 26,251 | Feb 26, 2025, 04:09 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 25, 2025 | Sale | $480.95 | 1,767 | 849,839 | 24,484 | Feb 26, 2025, 04:09 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 14, 2025 | Tax Payment (Shares) | $463.46 | 1,529 | 708,630 | 27,907 | Feb 19, 2025, 04:26 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 11, 2025 | Sale | $459.83 | 1,747 | 803,323 | 23,225 | Feb 12, 2025, 04:29 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 10, 2025 | Tax Payment (Shares) | $467.98 | 876 | 409,950 | 24,972 | Feb 12, 2025, 04:29 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Jun 11, 2024 | Tax Payment (Shares) | $481.96 | 6,824 | 3,288,895 | 23,260 | Jun 13, 2024, 04:09 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Jun 12, 2024 | Sale | $478.00 | 7,288 | 3,483,664 | 15,972 | Jun 13, 2024, 04:09 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 23, 2024 | Tax Payment (Shares) | $431.79 | 1,654 | 714,181 | 16,855 | Feb 27, 2024, 04:44 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 26, 2024 | Sale | $425.70 | 883 | 375,893 | 15,972 | Feb 27, 2024, 04:44 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 21, 2024 | Sale | $421.77 | 1,201 | 506,546 | 18,509 | Feb 23, 2024, 04:16 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 16, 2024 | Tax Payment (Shares) | $424.01 | 1,501 | 636,439 | 21,636 | Feb 21, 2024, 04:23 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 20, 2024 | Tax Payment (Shares) | $420.58 | 1,125 | 473,152 | 20,511 | Feb 21, 2024, 04:23 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 20, 2024 | Sale | $420.79 | 801 | 337,053 | 19,710 | Feb 21, 2024, 04:23 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 12, 2024 | Sale | $420.24 | 913 | 383,679 | 23,137 | Feb 13, 2024, 04:54 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Edward Morrow Atkinson III | EVP, Chief Technical Ops. Off. | Feb 09, 2024 | Tax Payment (Shares) | $422.74 | 832 | 351,720 | 24,050 | Feb 13, 2024, 04:54 PM |
