| RYTM | | RHYTHM PHARMACEUTICALS, INC. | Stuart A. Arbuckle | Director | Jun 23, 2026 | Option/RSU Exercise | - | 4,712 | - | 11,712 | Jun 25, 2026, 06:03 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Jul 01, 2025 | Tax Payment (Shares) | $450.23 | 37,243 | 16,767,916 | 63,368 | Jul 02, 2025, 04:16 PM |
| RYTM | | RHYTHM PHARMACEUTICALS, INC. | Stuart A. Arbuckle | Director | Jun 18, 2025 | Option/RSU Exercise | - | 4,000 | - | 7,000 | Jun 23, 2025, 04:51 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 26, 2025 | Tax Payment (Shares) | $479.61 | 7,071 | 3,391,322 | 62,935 | Feb 28, 2025, 04:31 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 24, 2025 | Tax Payment (Shares) | $483.28 | 4,716 | 2,279,148 | 70,006 | Feb 26, 2025, 04:07 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 14, 2025 | Tax Payment (Shares) | $463.46 | 2,724 | 1,262,465 | 74,722 | Feb 19, 2025, 04:25 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 10, 2025 | Tax Payment (Shares) | $467.98 | 3,220 | 1,506,896 | 69,543 | Feb 12, 2025, 04:26 PM |
| RYTM | | RHYTHM PHARMACEUTICALS, INC. | Stuart A. Arbuckle | Director | Jun 21, 2024 | Option/RSU Exercise | - | 3,000 | - | 3,000 | Jun 25, 2024, 04:41 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | May 15, 2024 | Sale | $430.93 | 69 | 29,734 | 49,691 | May 17, 2024, 04:24 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 26, 2024 | Sale | $425.70 | 5,034 | 2,142,974 | 49,691 | Feb 27, 2024, 04:37 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 23, 2024 | Tax Payment (Shares) | $431.79 | 4,714 | 2,035,458 | 54,725 | Feb 27, 2024, 04:37 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 21, 2024 | Sale | $421.77 | 3,603 | 1,519,637 | 59,439 | Feb 23, 2024, 04:12 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 16, 2024 | Tax Payment (Shares) | $424.01 | 4,499 | 1,907,621 | 71,219 | Feb 21, 2024, 04:19 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 20, 2024 | Tax Payment (Shares) | $420.58 | 3,373 | 1,418,616 | 67,846 | Feb 21, 2024, 04:19 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 20, 2024 | Sale | $420.79 | 4,804 | 2,021,475 | 63,042 | Feb 21, 2024, 04:19 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 09, 2024 | Tax Payment (Shares) | $422.74 | 3,177 | 1,343,045 | 80,013 | Feb 13, 2024, 04:51 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 12, 2024 | Sale | $420.24 | 4,295 | 1,804,931 | 75,718 | Feb 13, 2024, 04:51 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Dec 13, 2023 | Option/RSU Exercise | $187.53 | 8,603 | 1,613,321 | 65,159 | Dec 15, 2023, 04:20 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Dec 13, 2023 | Sale | $399.00 | 8,603 | 3,432,597 | 56,556 | Dec 15, 2023, 04:20 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Jun 15, 2023 | Sale | $349.00 | 8,603 | 3,002,447 | 56,556 | Jun 20, 2023, 04:07 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Jun 15, 2023 | Option/RSU Exercise | $187.53 | 8,603 | 1,613,321 | 65,159 | Jun 20, 2023, 04:07 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | May 30, 2023 | Sale | $329.82 | 82 | 27,045 | 56,556 | Jun 01, 2023, 04:16 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 24, 2023 | Tax Payment (Shares) | $289.12 | 4,714 | 1,362,912 | 61,590 | Feb 28, 2023, 04:47 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 27, 2023 | Sale | $287.47 | 5,034 | 1,447,143 | 57,756 | Feb 28, 2023, 04:47 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 22, 2023 | Sale | $294.33 | 2,401 | 706,679 | 68,576 | Feb 24, 2023, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 21, 2023 | Sale | $293.75 | 2,402 | 705,596 | 71,086 | Feb 22, 2023, 04:30 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 17, 2023 | Tax Payment (Shares) | $292.85 | 4,498 | 1,317,239 | 71,107 | Feb 22, 2023, 04:30 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 14, 2023 | Sale | $298.68 | 6,398 | 1,910,962 | 81,203 | Feb 16, 2023, 04:14 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 10, 2023 | Tax Payment (Shares) | $294.33 | 3,372 | 992,481 | 92,880 | Feb 14, 2023, 04:53 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 13, 2023 | Tax Payment (Shares) | $298.26 | 5,990 | 1,786,577 | 86,890 | Feb 14, 2023, 04:53 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 13, 2023 | Sale | $298.92 | 4,887 | 1,460,816 | 86,645 | Feb 14, 2023, 04:53 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Aug 15, 2022 | Option/RSU Exercise | $155.57 | 6,571 | 1,022,251 | 67,451 | Aug 17, 2022, 05:39 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Aug 15, 2022 | Sale | $303.93 | 22,173 | 6,738,991 | 66,197 | Aug 17, 2022, 05:39 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Aug 10, 2022 | Option/RSU Exercise | $155.57 | 64 | 9,956 | 61,060 | Aug 12, 2022, 04:05 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Aug 10, 2022 | Sale | $300.40 | 180 | 54,073 | 60,889 | Aug 12, 2022, 04:05 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Aug 09, 2022 | Sale | $300.67 | 5,690 | 1,710,817 | 61,896 | Aug 10, 2022, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Aug 09, 2022 | Option/RSU Exercise | $155.57 | 1,926 | 299,628 | 66,686 | Aug 10, 2022, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | May 16, 2022 | Sale | $251.19 | 133 | 33,408 | 64,882 | May 18, 2022, 04:21 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | May 02, 2022 | Sale | $263.98 | 306 | 80,778 | 64,760 | May 04, 2022, 05:21 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 24, 2022 | Tax Payment (Shares) | $227.86 | 7,246 | 1,651,074 | 65,066 | Feb 28, 2022, 05:19 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 17, 2022 | Tax Payment (Shares) | $232.51 | 4,126 | 959,336 | 72,312 | Feb 22, 2022, 04:54 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Feb 10, 2022 | Tax Payment (Shares) | $237.74 | 3,040 | 722,730 | 76,438 | Feb 14, 2022, 04:13 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, COO | Nov 15, 2021 | Sale | $187.26 | 3 | 562 | 41,104 | Nov 16, 2021, 04:05 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 24, 2021 | Tax Payment (Shares) | $217.57 | 2,898 | 630,518 | 44,737 | Feb 26, 2021, 04:07 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 25, 2021 | Sale | $213.54 | 3,634 | 775,989 | 44,357 | Feb 26, 2021, 04:07 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 17, 2021 | Tax Payment (Shares) | $211.75 | 6,240 | 1,321,320 | 55,460 | Feb 19, 2021, 04:08 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 18, 2021 | Sale | $211.82 | 7,825 | 1,657,481 | 54,438 | Feb 19, 2021, 04:08 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 11, 2021 | Sale | $210.55 | 5,156 | 1,085,593 | 62,500 | Feb 16, 2021, 04:07 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 10, 2021 | Tax Payment (Shares) | $214.16 | 3,101 | 664,110 | 66,856 | Feb 12, 2021, 04:04 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 03, 2021 | Option/RSU Exercise | $86.52 | 1,554 | 134,452 | 71,511 | Feb 05, 2021, 04:43 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 03, 2021 | Sale | $213.74 | 1,554 | 332,146 | 71,363 | Feb 05, 2021, 04:43 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Nov 16, 2020 | Sale | $223.64 | 7 | 1,565 | 35,184 | Nov 18, 2020, 04:11 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Nov 03, 2020 | Option/RSU Exercise | $86.52 | 1,553 | 134,366 | 36,732 | Nov 05, 2020, 04:16 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Nov 03, 2020 | Sale | $211.92 | 1,553 | 329,115 | 36,245 | Nov 05, 2020, 04:16 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Aug 03, 2020 | Option/RSU Exercise | $86.52 | 1,553 | 134,366 | 36,732 | Aug 05, 2020, 04:17 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Aug 03, 2020 | Sale | $278.39 | 1,553 | 432,337 | 36,561 | Aug 05, 2020, 04:17 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Jul 07, 2020 | Sale | $300.00 | 2,786 | 835,800 | 35,179 | Jul 09, 2020, 04:13 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Jul 07, 2020 | Option/RSU Exercise | $173.51 | 2,786 | 483,403 | 37,965 | Jul 09, 2020, 04:13 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | May 15, 2020 | Sale | $283.98 | 113 | 32,089 | 35,282 | May 19, 2020, 04:22 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | May 04, 2020 | Option/RSU Exercise | $86.52 | 1,553 | 134,366 | 36,732 | May 06, 2020, 04:38 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | May 04, 2020 | Sale | $260.76 | 1,553 | 404,957 | 36,092 | May 06, 2020, 04:38 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 25, 2020 | Sale | $233.74 | 3,634 | 849,418 | 38,003 | Feb 26, 2020, 04:30 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 24, 2020 | Tax Payment (Shares) | $239.23 | 2,898 | 693,289 | 38,813 | Feb 26, 2020, 04:30 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 17, 2020 | Tax Payment (Shares) | $241.50 | 2,496 | 602,784 | 44,839 | Feb 19, 2020, 04:32 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 18, 2020 | Sale | $243.56 | 3,128 | 761,842 | 44,079 | Feb 19, 2020, 04:32 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 10, 2020 | Tax Payment (Shares) | $240.95 | 8,942 | 2,154,575 | 58,621 | Feb 12, 2020, 05:13 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 11, 2020 | Sale | $246.09 | 11,286 | 2,777,325 | 57,691 | Feb 12, 2020, 05:13 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 06, 2020 | Sale | $239.42 | 2,787 | 667,253 | 68,839 | Feb 07, 2020, 04:08 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 06, 2020 | Option/RSU Exercise | $173.51 | 2,787 | 483,559 | 70,350 | Feb 07, 2020, 04:08 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Jan 31, 2020 | Option/RSU Exercise | $187.53 | 4,692 | 879,891 | 37,932 | Feb 04, 2020, 04:10 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Jan 31, 2020 | Sale | $238.65 | 4,692 | 1,119,746 | 33,240 | Feb 04, 2020, 04:10 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 03, 2020 | Option/RSU Exercise | $89.15 | 3,710 | 330,756 | 36,950 | Feb 04, 2020, 04:10 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVP, Chief Commercial Officer | Feb 03, 2020 | Sale | $231.12 | 3,710 | 857,465 | 36,510 | Feb 04, 2020, 04:10 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Nov 15, 2019 | Sale | $205.95 | 19 | 3,913 | 33,240 | Nov 19, 2019, 04:09 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Nov 13, 2019 | Option/RSU Exercise | $155.57 | 8,560 | 1,331,679 | 41,800 | Nov 15, 2019, 04:03 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Nov 13, 2019 | Sale | $205.57 | 8,560 | 1,759,679 | 33,240 | Nov 15, 2019, 04:03 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Nov 04, 2019 | Option/RSU Exercise | $89.15 | 3,708 | 330,578 | 35,395 | Nov 06, 2019, 04:11 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Nov 04, 2019 | Sale | $201.62 | 3,708 | 747,607 | 33,240 | Nov 06, 2019, 04:11 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Aug 08, 2019 | Option/RSU Exercise | $131.89 | 2,125 | 280,266 | 35,365 | Aug 12, 2019, 04:14 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Aug 08, 2019 | Sale | $181.89 | 2,125 | 386,516 | 33,240 | Aug 12, 2019, 04:14 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Aug 02, 2019 | Option/RSU Exercise | $91.05 | 2,155 | 196,213 | 34,395 | Aug 06, 2019, 04:41 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Aug 02, 2019 | Sale | $177.78 | 2,155 | 383,116 | 32,240 | Aug 06, 2019, 04:41 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Aug 05, 2019 | Option/RSU Exercise | $86.52 | 1,553 | 134,366 | 33,793 | Aug 06, 2019, 04:41 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Aug 05, 2019 | Sale | $176.44 | 1,553 | 274,011 | 32,240 | Aug 06, 2019, 04:41 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Jun 19, 2019 | Option/RSU Exercise | $131.89 | 2,125 | 280,266 | 35,365 | Jun 20, 2019, 04:53 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Jun 19, 2019 | Sale | $181.89 | 2,125 | 386,516 | 33,240 | Jun 20, 2019, 04:53 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | May 15, 2019 | Sale | $165.41 | 133 | 22,000 | 33,240 | May 17, 2019, 04:18 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | May 03, 2019 | Option/RSU Exercise | $86.52 | 1,553 | 134,366 | 34,793 | May 06, 2019, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | May 03, 2019 | Sale | $172.39 | 1,553 | 267,723 | 34,553 | May 06, 2019, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | May 02, 2019 | Option/RSU Exercise | $91.05 | 2,155 | 196,213 | 35,395 | May 06, 2019, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | May 02, 2019 | Sale | $169.27 | 2,155 | 364,768 | 34,197 | May 06, 2019, 04:06 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Apr 15, 2019 | Sale | $181.75 | 5,624 | 1,022,148 | 36,272 | Apr 17, 2019, 04:30 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Feb 11, 2019 | Sale | $180.21 | 33,073 | 5,959,969 | 61,280 | Feb 13, 2019, 04:37 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Feb 04, 2019 | Sale | $186.20 | 18,309 | 3,409,083 | 53,311 | Feb 06, 2019, 04:50 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Feb 04, 2019 | Option/RSU Exercise | $99.97 | 7,959 | 795,657 | 54,711 | Feb 06, 2019, 04:50 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Jan 22, 2019 | Option/RSU Exercise | $131.89 | 2,125 | 280,266 | 48,877 | Jan 24, 2019, 04:46 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Jan 22, 2019 | Sale | $193.48 | 2,125 | 411,145 | 46,752 | Jan 24, 2019, 04:46 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Nov 15, 2018 | Sale | $163.75 | 29 | 4,749 | 46,752 | Nov 19, 2018, 05:28 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Nov 07, 2018 | Sale | $179.00 | 2,125 | 380,375 | 46,752 | Nov 08, 2018, 04:26 PM |
| VRTX | | VERTEX PHARMACEUTICALS INC / MA | Stuart A. Arbuckle | EVPChief Commercial Officer | Nov 07, 2018 | Option/RSU Exercise | $131.89 | 2,125 | 280,266 | 48,877 | Nov 08, 2018, 04:26 PM |
