| Symbol | Company | Owner | Relationship | Date | Transaction | Cost | # Shares | Value ($) | Total Shares | Filing | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Nov 15, 2023 | Sale | $50.00 | 2,000 | 100,000 | 16,346 | Nov 17, 2023, 04:58 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Sep 26, 2023 | Sale | $45.13 | 2,000 | 90,254 | 18,346 | Sep 28, 2023, 06:03 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Jul 18, 2023 | Sale | $42.00 | 3,555 | 149,310 | 20,346 | Jul 19, 2023, 06:05 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Jan 17, 2023 | Sale | $40.00 | 2,000 | 80,000 | 16,791 | Jan 18, 2023, 08:19 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Jul 15, 2022 | Sale | $38.24 | 1,333 | 50,977 | 19,435 | Jul 19, 2022, 07:20 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Jul 15, 2021 | Sale | $35.30 | 4,334 | 152,989 | 18,126 | Jul 19, 2021, 08:14 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Oct 20, 2020 | Sale | $46.86 | 2,889 | 135,386 | 13,794 | Oct 22, 2020, 05:36 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Dec 23, 2019 | Option Exercise | $48.70 | 2,000 | 97,404 | 13,683 | Dec 23, 2019, 07:28 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Dec 16, 2019 | Option Exercise | $50.49 | 2,000 | 100,977 | 13,683 | Dec 18, 2019, 05:07 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Dec 09, 2019 | Sale | $49.64 | 2,000 | 99,275 | 13,683 | Dec 10, 2019, 06:54 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Dec 02, 2019 | Sale | $49.81 | 2,000 | 99,613 | 13,683 | Dec 04, 2019, 06:26 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Nov 25, 2019 | Sale | $62.90 | 812 | 51,075 | 12,683 | Nov 26, 2019, 05:43 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Nov 20, 2019 | Sale | $60.00 | 2,000 | 120,000 | 13,495 | Nov 21, 2019, 06:40 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Mar 29, 2018 | Sale | $35.29 | 4,000 | 141,140 | 11,939 | Mar 30, 2018, 03:51 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Mar 15, 2018 | Sale | $37.77 | 4,000 | 151,098 | 10,839 | Mar 16, 2018, 04:19 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Feb 28, 2018 | Sale | $43.72 | 6,000 | 262,317 | 12,039 | Mar 01, 2018, 05:52 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Feb 15, 2018 | Option Exercise | $42.26 | 6,000 | 253,574 | 11,539 | Feb 16, 2018, 06:00 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Jan 30, 2018 | Option Exercise | $44.19 | 6,000 | 265,170 | 12,939 | Jan 31, 2018, 04:18 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Jan 16, 2018 | Option Exercise | $44.03 | 6,000 | 264,156 | 11,539 | Jan 17, 2018, 09:28 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Dec 29, 2017 | Option Exercise | $39.52 | 6,000 | 237,090 | 12,939 | Jan 02, 2018, 05:50 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Dec 15, 2017 | Option Exercise | $40.08 | 6,000 | 240,480 | 12,939 | Dec 19, 2017, 08:27 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Nov 30, 2017 | Option Exercise | $41.01 | 6,000 | 246,060 | 12,939 | Dec 01, 2017, 07:04 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Nov 15, 2017 | Option Exercise | $41.02 | 4,500 | 184,568 | 9,377 | Nov 17, 2017, 05:57 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Nov 16, 2017 | Option Exercise | $12.94 | 2,812 | 36,387 | 9,939 | Nov 17, 2017, 05:57 PM | |
| IONS | IONIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Nov 13, 2017 | Sale | $55.39 | 3,000 | 166,170 | 7,127 | Nov 14, 2017, 06:29 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Nov 11, 2015 | Sale | $37.57 | 13,750 | 516,547 | 9,293 | Nov 12, 2015, 07:02 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Mar 05, 2015 | Sale | $35.20 | 17,000 | 598,481 | 11,095 | Mar 09, 2015, 07:25 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Jan 24, 2014 | Sale | $32.03 | 20,626 | 660,638 | 9,813 | Jan 24, 2014, 08:26 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Nov 25, 2013 | Sale | $36.86 | 6,000 | 221,156 | 2,313 | Nov 27, 2013, 04:40 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Aug 09, 2013 | Sale | $19.20 | 37,500 | 720,076 | 15,813 | Aug 13, 2013, 07:45 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Mar 20, 2013 | Option Exercise | $15.80 | 7,848 | 123,989 | 2,500 | Mar 21, 2013, 08:25 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Mar 19, 2013 | Option Exercise | $11.96 | 7,452 | 89,163 | 3,726 | Mar 21, 2013, 08:24 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Mar 19, 2013 | Option Exercise | $11.96 | 14,906 | 178,350 | 3,826 | Mar 21, 2013, 08:24 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Mar 20, 2013 | Sale | $15.17 | 23,682 | 359,256 | 4,167 | Mar 21, 2013, 08:24 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Mar 20, 2013 | Sale | $15.05 | 39,512 | 594,472 | 4,266 | Mar 21, 2013, 08:24 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Mar 13, 2013 | Sale | $11.60 | 27,734 | 321,800 | 6,766 | Mar 14, 2013, 09:00 PM | |
| ISIS | ISIS PHARMACEUTICALS INC | KLEIN JOSEPH III | Director | Mar 13, 2013 | Sale | $11.60 | 13,866 | 160,888 | 6,667 | Mar 14, 2013, 09:00 PM |
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