| Symbol | Company | Owner | Relationship | Date | Transaction | Cost | # Shares | Value ($) | Total Shares | Filing | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Mar 14, 2024 | Option Exercise | $1.60 | 250,000 | 400,000 | 978,388 | Mar 15, 2024, 04:19 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Apr 13, 2023 | Option Exercise | $0.90 | 222,198 | 200,000 | 728,388 | Apr 14, 2023, 04:39 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | Feb 22, 2022 | Sale | $19.56 | 84,515 | 1,653,113 | 1,220,036 | Feb 24, 2022, 08:22 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Nov 30, 2021 | Option Exercise | $0.36 | 2,222,222 | 800,000 | 5,061,929 | Dec 01, 2021, 04:12 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | May 11, 2021 | Sale | $7.33 | 140,770 | 1,031,194 | 1,293,600 | May 13, 2021, 08:32 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Dec 04, 2020 | Option Exercise | $0.63 | 793,528 | 500,002 | 2,839,707 | Jan 27, 2021, 08:16 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Dec 04, 2020 | Option Exercise | $0.63 | 793,528 | 500,002 | 1,986,729 | Dec 07, 2020, 04:21 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | May 13, 2020 | Option Exercise | $5.82 | 120,791 | 703,004 | 1,173,359 | May 15, 2020, 08:18 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | May 08, 2020 | Sale | $15.43 | 90,000 | 1,389,000 | 1,097,568 | May 08, 2020, 09:18 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | May 07, 2019 | Option Exercise | $1.08 | 370,370 | 400,000 | 1,189,872 | May 21, 2019, 04:46 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | May 07, 2019 | Buy | $1.08 | 370,370 | 400,000 | 1,189,872 | May 08, 2019, 05:13 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | Feb 21, 2019 | Sale | $12.82 | 52,500 | 673,163 | 1,068,501 | Feb 22, 2019, 07:35 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Dec 28, 2018 | Buy | $1.09 | 50,000 | 54,570 | 835,073 | Jan 02, 2019, 04:12 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Dec 26, 2018 | Buy | $0.95 | 90,000 | 85,878 | 758,672 | Dec 28, 2018, 04:21 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Dec 27, 2018 | Buy | $1.04 | 26,401 | 27,460 | 785,073 | Dec 28, 2018, 04:21 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Nov 15, 2018 | Buy | $1.33 | 200,000 | 265,080 | 368,672 | Nov 19, 2018, 04:03 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Nov 16, 2018 | Buy | $1.38 | 300,000 | 415,470 | 668,672 | Nov 19, 2018, 04:03 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | May 07, 2018 | Sale | $16.90 | 30,000 | 507,150 | 1,049,314 | May 07, 2018, 08:07 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | Mar 02, 2018 | Sale | $16.01 | 30,000 | 480,300 | 1,049,314 | Mar 02, 2018, 08:03 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Dec 04, 2017 | Option Exercise | $0.89 | 96,629 | 86,000 | 1,797,306 | Dec 06, 2017, 07:41 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | Sep 22, 2017 | Sale | $25.40 | 10,000 | 254,000 | 0 | Sep 22, 2017, 07:07 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | Sep 18, 2017 | Sale | $27.76 | 72,210 | 2,004,550 | 1,162,104 | Sep 20, 2017, 06:48 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | Sep 19, 2017 | Sale | $27.63 | 127,790 | 3,530,838 | 1,034,314 | Sep 20, 2017, 06:48 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Jul 25, 2017 | Buy | $0.91 | 1,000,000 | 910,000 | 1,770,677 | Jul 25, 2017, 06:06 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Mar 21, 2017 | Buy | $1.20 | 200,000 | 239,800 | 400,677 | Mar 23, 2017, 04:26 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Mar 22, 2017 | Buy | $1.23 | 300,000 | 368,100 | 700,677 | Mar 23, 2017, 04:26 PM | |
| EXEL | EXELIXIS, INC. | PAPADOPOULOS STELIOS | Director | Mar 20, 2017 | Sale | $16.09 | 20,000 | 321,900 | 1,238,471 | Mar 21, 2017, 07:28 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Aug 07, 2015 | Option Exercise | $1.55 | 50,677 | 78,801 | 200,677 | Aug 07, 2015, 06:05 PM | |
| BIIB | BIOGEN INC. | PAPADOPOULOS STELIOS | Director | Jul 27, 2015 | Buy | $304.78 | 5,000 | 1,523,880 | 5,000 | Jul 27, 2015, 05:03 PM | |
| BIIB | BIOGEN INC. | PAPADOPOULOS STELIOS | Director | Jul 27, 2015 | Buy | $304.98 | 5,000 | 1,524,895 | 5,000 | Jul 27, 2015, 05:03 PM | |
| RGLS | Regulus Therapeutics Inc. | PAPADOPOULOS STELIOS | Director | Dec 12, 2014 | Option Exercise | $0.38 | 150,000 | 57,000 | 150,000 | Dec 15, 2014, 12:58 PM | |
| BIIB | BIOGEN IDEC INC. | PAPADOPOULOS STELIOS | Director | Jun 11, 2013 | Sale | $219.62 | 2,020 | 443,632 | 12,930 | Jun 13, 2013, 04:27 PM | |
| BIIB | BIOGEN IDEC INC. | PAPADOPOULOS STELIOS | Director | Mar 11, 2013 | Sale | $115.35 | 93,350 | 10,767,466 | 49,950 | Mar 12, 2013, 02:22 PM | |
| BGMD | BG Medicine, Inc. | PAPADOPOULOS STELIOS | Director | Jan 30, 2013 | Buy | $2.00 | 250,000 | 500,000 | 1,187,713 | Feb 01, 2013, 04:50 PM | |
| BGMD | BG Medicine, Inc. | PAPADOPOULOS STELIOS | Director | Nov 29, 2011 | Sale | $0.06 | 152,694 | 8,626 | 937,742 | Dec 01, 2011, 04:57 PM | |
| BGMD | BG Medicine, Inc. | PAPADOPOULOS STELIOS | Director | Nov 09, 2011 | Option Exercise | $0.90 | 336,441 | 302,797 | 787,175 | Nov 14, 2011, 07:53 AM | |
| BGMD | BG Medicine, Inc. | PAPADOPOULOS STELIOS | Director | Feb 09, 2011 | Option Exercise | $7.00 | 112,907 | 790,349 | 450,734 | Feb 11, 2011, 05:31 PM | |
| EXEL | EXELIXIS INC | PAPADOPOULOS STELIOS | Director | Aug 24, 2010 | Buy | $3.05 | 200,000 | 610,197 | 1,143,956 | Aug 25, 2010, 08:48 PM |
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