| Symbol | Company | Owner | Relationship | Date | Transaction | Cost | # Shares | Value ($) | Total Shares | Filing | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDCO | MEDICINES CO /DE | KESSLER ARMIN M | Director | May 10, 2018 | Option Exercise | $18.30 | 7,500 | 137,250 | 138,493 | May 14, 2018, 05:07 PM | |
| MDCO | MEDICINES CO /DE | KESSLER ARMIN M | Director | Jan 16, 2018 | Sale | $27.37 | 10,000 | 273,700 | 140,993 | Apr 18, 2018, 05:51 PM | |
| MDCO | MEDICINES CO /DE | KESSLER ARMIN M | Director | Apr 16, 2018 | Sale | $30.05 | 10,000 | 300,500 | 130,993 | Apr 18, 2018, 05:51 PM | |
| MDCO | MEDICINES CO /DE | KESSLER ARMIN M | Director | Mar 13, 2017 | Option Exercise | $19.60 | 7,500 | 147,000 | 147,756 | Mar 15, 2017, 05:03 PM | |
| MDCO | MEDICINES CO /DE | KESSLER ARMIN M | Director | Mar 07, 2016 | Option Exercise | $24.29 | 23,100 | 561,042 | 144,930 | Mar 08, 2016, 05:44 PM | |
| MDCO | MEDICINES CO /DE | KESSLER ARMIN M | Director | May 13, 2015 | Sale | $23.46 | 27,475 | 644,473 | 137,874 | May 15, 2015, 05:15 PM | |
| MDCO | MEDICINES CO /DE | KESSLER ARMIN M | Director | May 29, 2013 | Sale | $27.14 | 21,250 | 576,687 | 123,185 | May 31, 2013, 06:39 PM | |
| MDCO | MEDICINES CO /DE | KESSLER ARMIN M | Director | Dec 14, 2012 | Sale | $21.76 | 11,500 | 250,240 | 110,685 | Dec 18, 2012, 04:05 PM | |
| GPRO | GEN PROBE INC | KESSLER ARMIN M | Director | Aug 01, 2012 | Option Exercise | $82.75 | 12,181 | 1,007,978 | 0 | Aug 02, 2012, 04:46 PM | |
| GPRO | GEN PROBE INC | KESSLER ARMIN M | Director | Apr 02, 2012 | Option Exercise | $67.26 | 156 | 10,493 | 12,181 | Apr 04, 2012, 05:22 PM | |
| MDCO | MEDICINES CO /DE | KESSLER ARMIN M | Director | Mar 14, 2012 | Option Exercise | $8.51 | 7,500 | 63,825 | 117,099 | Mar 15, 2012, 04:14 PM | |
| GPRO | GEN PROBE INC | KESSLER ARMIN M | Director | Mar 06, 2012 | Sale | $29.87 | 12,853 | 383,971 | 14,878 | Mar 08, 2012, 05:06 PM | |
| GPRO | GEN PROBE INC | KESSLER ARMIN M | Director | Jan 03, 2012 | Option Exercise | $58.93 | 178 | 10,490 | 4,878 | Jan 05, 2012, 05:38 PM | |
| GPRO | GEN PROBE INC | KESSLER ARMIN M | Director | Oct 03, 2011 | Option Exercise | $55.04 | 190 | 10,458 | 4,700 | Oct 05, 2011, 04:45 PM | |
| GPRO | GEN PROBE INC | KESSLER ARMIN M | Director | Jul 01, 2011 | Option Exercise | $69.79 | 150 | 10,469 | 4,510 | Jul 06, 2011, 05:24 PM | |
| MDCO | MEDICINES CO /DE | KESSLER ARMIN M | Director | May 18, 2011 | Option Exercise | $15.36 | 15,000 | 230,400 | 111,185 | May 20, 2011, 04:07 PM | |
| GPRO | GEN PROBE INC | KESSLER ARMIN M | Director | Apr 01, 2011 | Option Exercise | $66.06 | 158 | 10,437 | 4,360 | Apr 05, 2011, 04:15 PM | |
| GPRO | GEN PROBE INC | KESSLER ARMIN M | Director | Jan 03, 2011 | Option Exercise | $59.40 | 176 | 10,454 | 4,202 | Jan 05, 2011, 03:22 PM | |
| GPRO | GEN PROBE INC | KESSLER ARMIN M | Director | Nov 04, 2010 | Sale | $49.15 | 11,667 | 573,470 | 4,026 | Nov 05, 2010, 04:52 PM |
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