| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| ITOS | Chief Operating Officer | Mar 28, 2023 | Option Exercise | $2.95 | 40,226 | 118,667 | 93,898 | Mar 29, 2023, 08:00 PM |
| ITOS | Chief Operating Officer | Jul 30, 2021 | Option Exercise | $2.95 | 53,672 | 158,332 | 53,672 | Aug 05, 2021, 07:55 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| ITOS | Chief Operating Officer | Mar 28, 2023 | Option Exercise | 118,667 |
| ITOS | Chief Operating Officer | Jul 30, 2021 | Option Exercise | 158,332 |